BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 43 hits Enz. Inhib. hit(s) with Target = 'Neurotensin receptor 3' AND taxid = 9606   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Neurotensin receptor 3


(Homo sapiens)
BDBM50445041
PNG
(CHEMBL3098768)
Show SMILES OC(=O)c1cc(ccc1C(=O)Nc1ccc2CCCCc2n1)C(F)(F)F
Show InChI InChI=1S/C18H15F3N2O3/c19-18(20,21)11-6-7-12(13(9-11)17(25)26)16(24)23-15-8-5-10-3-1-2-4-14(10)22-15/h5-9H,1-4H2,(H,25,26)(H,22,23,24)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 100n/an/an/an/an/an/a



H. Lundbeck A/S

Curated by ChEMBL


Assay Description
Displacement of [3H]-neurotensin from sortilin (unknown origin) incubated 30 mins prior to [3H]-neurotensin addition measured after 6 hrs by scintill...


Citation and Details
More data for this
Ligand-Target Pair
Neurotensin receptor 3


(Homo sapiens)
BDBM50445042
PNG
(CHEMBL3098767)
Show SMILES Cc1ccc(NC(=O)c2ccc(cc2C(O)=O)C(F)(F)F)nc1C
Show InChI InChI=1S/C16H13F3N2O3/c1-8-3-6-13(20-9(8)2)21-14(22)11-5-4-10(16(17,18)19)7-12(11)15(23)24/h3-7H,1-2H3,(H,23,24)(H,20,21,22)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 170n/an/an/an/an/an/a



H. Lundbeck A/S

Curated by ChEMBL


Assay Description
Displacement of [3H]-neurotensin from sortilin (unknown origin) incubated 30 mins prior to [3H]-neurotensin addition measured after 6 hrs by scintill...


Citation and Details
More data for this
Ligand-Target Pair
Neurotensin receptor 3


(Homo sapiens)
BDBM50248034
PNG
(2-{[1-(7-Chloro-quinolin-4-yl)-5-(2,6-dimethoxy-ph...)
Show SMILES COc1cccc(OC)c1-c1cc(nn1-c1ccnc2cc(Cl)ccc12)C(=O)NC1(C2CC3CC(C2)CC1C3)C(O)=O
Show InChI InChI=1S/C32H31ClN4O5/c1-41-27-4-3-5-28(42-2)29(27)26-16-24(36-37(26)25-8-9-34-23-15-21(33)6-7-22(23)25)30(38)35-32(31(39)40)19-11-17-10-18(13-19)14-20(32)12-17/h3-9,15-20H,10-14H2,1-2H3,(H,35,38)(H,39,40)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
Article
PubMed
n/an/a 238n/an/an/an/an/an/a



Durham University

Curated by ChEMBL


Assay Description
Binding affinity to NTR3 (unknown origin)


Citation and Details
More data for this
Ligand-Target Pair
Neurotensin receptor 3


(Homo sapiens)
BDBM50445054
PNG
(CHEMBL3098745)
Show SMILES Cc1cccc(NC(=O)c2ccc(cc2C(O)=O)C(F)(F)F)n1
Show InChI InChI=1S/C15H11F3N2O3/c1-8-3-2-4-12(19-8)20-13(21)10-6-5-9(15(16,17)18)7-11(10)14(22)23/h2-7H,1H3,(H,22,23)(H,19,20,21)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
PDB
UniChem

Similars

AffyNet 
PDB
Article
PubMed
n/an/a 330n/an/an/an/an/an/a



H. Lundbeck A/S

Curated by ChEMBL


Assay Description
Displacement of [3H]-neurotensin from sortilin (unknown origin) incubated 30 mins prior to [3H]-neurotensin addition measured after 6 hrs by scintill...


Citation and Details
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Neurotensin receptor 3


(Homo sapiens)
BDBM50130880
PNG
(CHEMBL407196 | NT(1-13) | neurotensin | pGlu-Leu-T...)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCCN)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H]1CCC(=O)N1)C(=O)N[C@@H](CC(C)C)C(O)=O
Show InChI InChI=1S/C78H121N21O20/c1-7-43(6)63(73(115)96-57(76(118)119)37-42(4)5)97-70(112)55(39-45-21-25-47(101)26-22-45)95-72(114)59-18-13-35-99(59)75(117)52(16-11-33-86-78(83)84)90-64(106)48(15-10-32-85-77(81)82)89-71(113)58-17-12-34-98(58)74(116)51(14-8-9-31-79)91-69(111)56(40-60(80)102)94-66(108)50(28-30-62(104)105)88-68(110)54(38-44-19-23-46(100)24-20-44)93-67(109)53(36-41(2)3)92-65(107)49-27-29-61(103)87-49/h19-26,41-43,48-59,63,100-101H,7-18,27-40,79H2,1-6H3,(H2,80,102)(H,87,103)(H,88,110)(H,89,113)(H,90,106)(H,91,111)(H,92,107)(H,93,109)(H,94,108)(H,95,114)(H,96,115)(H,97,112)(H,104,105)(H,118,119)(H4,81,82,85)(H4,83,84,86)/t43-,48-,49-,50-,51-,52-,53-,54-,55-,56-,57-,58-,59-,63-/m0/s1
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 360n/an/an/an/an/an/a



H. Lundbeck A/S

Curated by ChEMBL


Assay Description
Displacement of [3H]-neurotensin from human sortilin incubated 30 mins prior to [3H]-neurotensin addition measured after 6 hrs by scintillation proxi...


Citation and Details
More data for this
Ligand-Target Pair
Neurotensin receptor 3


(Homo sapiens)
BDBM50133194
PNG
(CHEMBL133849 | Compound KK2)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)CCCN=C(N)NC(=O)[C@@H](N)CCCCCNC)C(=O)N[C@@H](CC(C)C)C(O)=O
Show InChI InChI=1S/C40H68N10O8/c1-6-25(4)33(37(55)47-31(39(57)58)22-24(2)3)48-35(53)30(23-26-15-17-27(51)18-16-26)46-36(54)32-14-11-21-50(32)38(56)29(42)13-10-20-45-40(43)49-34(52)28(41)12-8-7-9-19-44-5/h15-18,24-25,28-33,44,51H,6-14,19-23,41-42H2,1-5H3,(H,46,54)(H,47,55)(H,48,53)(H,57,58)(H3,43,45,49,52)/t25-,28-,29-,30-,31-,32-,33-/m0/s1
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 400n/an/an/an/an/an/a



Medical University of South Carolina

Curated by ChEMBL


Assay Description
Evaluated for binding affinity by inhibiting binding of [125I]Tyr(3)-NT to human Neurotensin receptor 3


Citation and Details
More data for this
Ligand-Target Pair
Neurotensin receptor 3


(Homo sapiens)
BDBM50133192
PNG
(CHEMBL439494 | Compound NT)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCCN)NC(=O)[C@H](CC(N)=O)NC(=O)CNC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)CCC(O)=O)C(O)=O
Show InChI InChI=1S/C69H108N20O18/c1-5-38(4)56(67(106)107)87-62(101)49(34-40-19-23-42(91)24-20-40)86-64(103)52-16-11-31-89(52)66(105)46(14-9-29-78-69(75)76)82-59(98)44(13-8-28-77-68(73)74)81-63(102)51-15-10-30-88(51)65(104)45(12-6-7-27-70)83-61(100)50(35-53(72)92)80-54(93)36-79-58(97)48(33-39-17-21-41(90)22-18-39)85-60(99)47(32-37(2)3)84-57(96)43(71)25-26-55(94)95/h17-24,37-38,43-52,56,90-91H,5-16,25-36,70-71H2,1-4H3,(H2,72,92)(H,79,97)(H,80,93)(H,81,102)(H,82,98)(H,83,100)(H,84,96)(H,85,99)(H,86,103)(H,87,101)(H,94,95)(H,106,107)(H4,73,74,77)(H4,75,76,78)/t38-,43-,44-,45-,46-,47-,48-,49-,50-,51-,52-,56-/m0/s1
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 440n/an/an/an/an/an/a



Medical University of South Carolina

Curated by ChEMBL


Assay Description
Evaluated for binding affinity by inhibiting binding of [125I]Tyr(3)-NT to human Neurotensin receptor 3


Citation and Details
More data for this
Ligand-Target Pair
Neurotensin receptor 3


(Homo sapiens)
BDBM50133188
PNG
(CHEMBL336836 | Compound KK17)
Show SMILES CCNC(N)=NCCC[C@H](N)C(=O)NC(N)=NCCC[C@H](N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(O)=O
Show InChI InChI=1S/C40H68N12O8/c1-6-24(5)32(36(57)49-30(38(59)60)21-23(3)4)50-34(55)29(22-25-14-16-26(53)17-15-25)48-35(56)31-13-10-20-52(31)37(58)28(42)12-9-19-47-40(44)51-33(54)27(41)11-8-18-46-39(43)45-7-2/h14-17,23-24,27-32,53H,6-13,18-22,41-42H2,1-5H3,(H,48,56)(H,49,57)(H,50,55)(H,59,60)(H3,43,45,46)(H3,44,47,51,54)/t24-,27-,28-,29-,30-,31-,32-/m0/s1
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 480n/an/an/an/an/an/a



Medical University of South Carolina

Curated by ChEMBL


Assay Description
Evaluated for binding affinity by inhibiting binding of [125I]Tyr(3)-NT to human Neurotensin receptor 3


Citation and Details
More data for this
Ligand-Target Pair
Neurotensin receptor 3


(Homo sapiens)
BDBM50133207
PNG
(CHEMBL133378 | Compound KK11)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)CCCN=C(N)NC(=O)[C@@H](N)CCCN(C)C)C(=O)N[C@@H](CC(C)C)C(O)=O
Show InChI InChI=1S/C39H66N10O8/c1-7-24(4)32(36(54)45-30(38(56)57)21-23(2)3)46-34(52)29(22-25-14-16-26(50)17-15-25)44-35(53)31-13-10-20-49(31)37(55)28(41)11-8-18-43-39(42)47-33(51)27(40)12-9-19-48(5)6/h14-17,23-24,27-32,50H,7-13,18-22,40-41H2,1-6H3,(H,44,53)(H,45,54)(H,46,52)(H,56,57)(H3,42,43,47,51)/t24-,27-,28-,29-,30-,31-,32-/m0/s1
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 480n/an/an/an/an/an/a



Medical University of South Carolina

Curated by ChEMBL


Assay Description
Evaluated for binding affinity by inhibiting binding of [125I]Tyr(3)-NT to human Neurotensin receptor 3


Citation and Details
More data for this
Ligand-Target Pair
Neurotensin receptor 3


(Homo sapiens)
BDBM50445044
PNG
(CHEMBL3098765)
Show SMILES Cc1nccc(NC(=O)c2ccc(Br)cc2C(O)=O)n1
Show InChI InChI=1S/C13H10BrN3O3/c1-7-15-5-4-11(16-7)17-12(18)9-3-2-8(14)6-10(9)13(19)20/h2-6H,1H3,(H,19,20)(H,15,16,17,18)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
AffyNet 
Article
PubMed
n/an/a 490n/an/an/an/an/an/a



H. Lundbeck A/S

Curated by ChEMBL


Assay Description
Displacement of [3H]-neurotensin from sortilin (unknown origin) incubated 30 mins prior to [3H]-neurotensin addition measured after 6 hrs by scintill...


Citation and Details
More data for this
Ligand-Target Pair
Neurotensin receptor 3


(Homo sapiens)
BDBM50133201
PNG
(CHEMBL132524 | Compound KK18)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)CCCN=C(N)NC(=O)[C@@H](N)CCCNC1NCCN1)C(=O)N[C@@H](CC(C)C)C(O)=O
Show InChI InChI=1S/C40H68N12O8/c1-5-24(4)32(36(57)49-30(38(59)60)21-23(2)3)50-34(55)29(22-25-12-14-26(53)15-13-25)48-35(56)31-11-8-20-52(31)37(58)28(42)10-7-16-44-39(43)51-33(54)27(41)9-6-17-45-40-46-18-19-47-40/h12-15,23-24,27-32,40,45-47,53H,5-11,16-22,41-42H2,1-4H3,(H,48,56)(H,49,57)(H,50,55)(H,59,60)(H3,43,44,51,54)/t24-,27-,28-,29-,30-,31-,32-/m0/s1
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 510n/an/an/an/an/an/a



Medical University of South Carolina

Curated by ChEMBL


Assay Description
Evaluated for binding affinity by inhibiting binding of [125I]Tyr(3)-NT to human Neurotensin receptor 3


Citation and Details
More data for this
Ligand-Target Pair
Neurotensin receptor 3


(Homo sapiens)
BDBM50133190
PNG
(CHEMBL430910 | Compound KK5)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)CCCN=C(N)NC(=O)[C@@H](N)CCCCN)C(=O)N[C@@H](CC(C)C)C(O)=O
Show InChI InChI=1S/C38H64N10O8/c1-5-23(4)31(35(53)45-29(37(55)56)20-22(2)3)46-33(51)28(21-24-13-15-25(49)16-14-24)44-34(52)30-12-9-19-48(30)36(54)27(41)11-8-18-43-38(42)47-32(50)26(40)10-6-7-17-39/h13-16,22-23,26-31,49H,5-12,17-21,39-41H2,1-4H3,(H,44,52)(H,45,53)(H,46,51)(H,55,56)(H3,42,43,47,50)/t23-,26-,27-,28-,29-,30-,31-/m0/s1
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 512n/an/an/an/an/an/a



Medical University of South Carolina

Curated by ChEMBL


Assay Description
Evaluated for binding affinity by inhibiting binding of [125I]Tyr(3)-NT to human Neurotensin receptor 3


Citation and Details
More data for this
Ligand-Target Pair
Neurotensin receptor 3


(Homo sapiens)
BDBM50133202
PNG
(CHEMBL132794 | Compound KK4)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)CCCN=C(N)NC(=O)[C@@H](N)CCCCC[N+](C)(C)C)C(=O)N[C@@H](CC(C)C)C(O)=O
Show InChI InChI=1S/C42H72N10O8/c1-8-27(4)35(39(57)48-33(41(59)60)24-26(2)3)49-37(55)32(25-28-17-19-29(53)20-18-28)47-38(56)34-16-13-22-51(34)40(58)31(44)15-12-21-46-42(45)50-36(54)30(43)14-10-9-11-23-52(5,6)7/h17-20,26-27,30-35H,8-16,21-25,43-44H2,1-7H3,(H7-,45,46,47,48,49,50,53,54,55,56,57,59,60)/p+1/t27-,30-,31-,32-,33-,34-,35-/m0/s1
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 550n/an/an/an/an/an/a



Medical University of South Carolina

Curated by ChEMBL


Assay Description
Evaluated for binding affinity by inhibiting binding of [125I]Tyr(3)-NT to human Neurotensin receptor 3


Citation and Details
More data for this
Ligand-Target Pair
Neurotensin receptor 3


(Homo sapiens)
BDBM50133193
PNG
(CHEMBL337721 | Neurotensin analogue)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)CCCN=C(N)NC(=O)[C@@H](N)CCCN1CCN=C1N)C(=O)N[C@@H](CC(C)C)C(O)=O
Show InChI InChI=1S/C40H66N12O8/c1-5-24(4)32(36(57)48-30(38(59)60)21-23(2)3)49-34(55)29(22-25-12-14-26(53)15-13-25)47-35(56)31-11-8-19-52(31)37(58)28(42)9-6-16-45-39(43)50-33(54)27(41)10-7-18-51-20-17-46-40(51)44/h12-15,23-24,27-32,53H,5-11,16-22,41-42H2,1-4H3,(H2,44,46)(H,47,56)(H,48,57)(H,49,55)(H,59,60)(H3,43,45,50,54)/t24-,27-,28-,29-,30-,31-,32-/m0/s1
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 590n/an/an/an/an/an/a



Medical University of South Carolina

Curated by ChEMBL


Assay Description
Evaluated for binding affinity by inhibiting binding of [125I]Tyr(3)-NT to human Neurotensin receptor 3


Citation and Details
More data for this
Ligand-Target Pair
Neurotensin receptor 3


(Homo sapiens)
BDBM50240845
PNG
((S)-2-{(2S,3R)-2-[(S)-2-({(S)-1-[(S)-2-((S)-2-Amin...)
Show SMILES CC[C@@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCCN=C(N)N)C(=O)N[C@@H](CC(C)C)C(O)=O
Show InChI InChI=1S/C38H64N12O8/c1-5-22(4)30(34(55)48-28(36(57)58)19-21(2)3)49-32(53)27(20-23-12-14-24(51)15-13-23)47-33(54)29-11-8-18-50(29)35(56)26(10-7-17-45-38(42)43)46-31(52)25(39)9-6-16-44-37(40)41/h12-15,21-22,25-30,51H,5-11,16-20,39H2,1-4H3,(H,46,52)(H,47,54)(H,48,55)(H,49,53)(H,57,58)(H4,40,41,44)(H4,42,43,45)/t22-,25+,26+,27+,28+,29+,30+/m1/s1
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 640n/an/an/an/an/an/a



Medical University of South Carolina

Curated by ChEMBL


Assay Description
Evaluated for binding affinity by inhibiting binding of [125I]Tyr(3)-NT to human Neurotensin receptor 3


Citation and Details
More data for this
Ligand-Target Pair
Neurotensin receptor 3


(Homo sapiens)
BDBM50133195
PNG
(CHEMBL133340 | Compound KK10)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)CCCN=C(N)NC(=O)[C@@H](N)CCCNC)C(=O)N[C@@H](CC(C)C)C(O)=O
Show InChI InChI=1S/C38H64N10O8/c1-6-23(4)31(35(53)45-29(37(55)56)20-22(2)3)46-33(51)28(21-24-13-15-25(49)16-14-24)44-34(52)30-12-9-19-48(30)36(54)27(40)11-8-18-43-38(41)47-32(50)26(39)10-7-17-42-5/h13-16,22-23,26-31,42,49H,6-12,17-21,39-40H2,1-5H3,(H,44,52)(H,45,53)(H,46,51)(H,55,56)(H3,41,43,47,50)/t23-,26-,27-,28-,29-,30-,31-/m0/s1
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 640n/an/an/an/an/an/a



Medical University of South Carolina

Curated by ChEMBL


Assay Description
Evaluated for binding affinity by inhibiting binding of [125I]Tyr(3)-NT to human Neurotensin receptor 3


Citation and Details
More data for this
Ligand-Target Pair
Neurotensin receptor 3


(Homo sapiens)
BDBM50133187
PNG
(CHEMBL133850 | Compound KK3)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)CCCN=C(N)NC(=O)[C@@H](N)CCCCCN(C)C)C(=O)N[C@@H](CC(C)C)C(O)=O
Show InChI InChI=1S/C41H70N10O8/c1-7-26(4)34(38(56)47-32(40(58)59)23-25(2)3)48-36(54)31(24-27-16-18-28(52)19-17-27)46-37(55)33-15-12-22-51(33)39(57)30(43)14-11-20-45-41(44)49-35(53)29(42)13-9-8-10-21-50(5)6/h16-19,25-26,29-34,52H,7-15,20-24,42-43H2,1-6H3,(H,46,55)(H,47,56)(H,48,54)(H,58,59)(H3,44,45,49,53)/t26-,29-,30-,31-,32-,33-,34-/m0/s1
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 700n/an/an/an/an/an/a



Medical University of South Carolina

Curated by ChEMBL


Assay Description
Evaluated for binding affinity by inhibiting binding of [125I]Tyr(3)-NT to human Neurotensin receptor 3


Citation and Details
More data for this
Ligand-Target Pair
Neurotensin receptor 3


(Homo sapiens)
BDBM50445058
PNG
(CHEMBL3098741)
Show SMILES Cc1cccc(NC(=O)c2ccc(Br)cc2C(O)=O)n1
Show InChI InChI=1S/C14H11BrN2O3/c1-8-3-2-4-12(16-8)17-13(18)10-6-5-9(15)7-11(10)14(19)20/h2-7H,1H3,(H,19,20)(H,16,17,18)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 710n/an/an/an/an/an/a



H. Lundbeck A/S

Curated by ChEMBL


Assay Description
Displacement of [3H]-neurotensin from sortilin (unknown origin) incubated 30 mins prior to [3H]-neurotensin addition measured after 6 hrs by scintill...


Citation and Details
More data for this
Ligand-Target Pair
Neurotensin receptor 3


(Homo sapiens)
BDBM50133198
PNG
(CHEMBL434227 | Compound KK16)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)CCCN=C(N)NC(=O)[C@@H](N)CCCN=C(N)NC)C(=O)N[C@@H](CC(C)C)C(O)=O
Show InChI InChI=1S/C39H66N12O8/c1-6-23(4)31(35(56)48-29(37(58)59)20-22(2)3)49-33(54)28(21-24-13-15-25(52)16-14-24)47-34(55)30-12-9-19-51(30)36(57)27(41)11-8-18-46-39(43)50-32(53)26(40)10-7-17-45-38(42)44-5/h13-16,22-23,26-31,52H,6-12,17-21,40-41H2,1-5H3,(H,47,55)(H,48,56)(H,49,54)(H,58,59)(H3,42,44,45)(H3,43,46,50,53)/t23-,26-,27-,28-,29-,30-,31-/m0/s1
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 720n/an/an/an/an/an/a



Medical University of South Carolina

Curated by ChEMBL


Assay Description
Evaluated for binding affinity by inhibiting binding of [125I]Tyr(3)-NT to human Neurotensin receptor 3


Citation and Details
More data for this
Ligand-Target Pair
Neurotensin receptor 3


(Homo sapiens)
BDBM50445051
PNG
(CHEMBL3098752)
Show SMILES Cc1cccc(NC(=O)c2cc(Cl)c(Cl)cc2C(O)=O)n1
Show InChI InChI=1S/C14H10Cl2N2O3/c1-7-3-2-4-12(17-7)18-13(19)8-5-10(15)11(16)6-9(8)14(20)21/h2-6H,1H3,(H,20,21)(H,17,18,19)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 830n/an/an/an/an/an/a



H. Lundbeck A/S

Curated by ChEMBL


Assay Description
Displacement of [3H]-neurotensin from sortilin (unknown origin) incubated 30 mins prior to [3H]-neurotensin addition measured after 6 hrs by scintill...


Citation and Details
More data for this
Ligand-Target Pair
Neurotensin receptor 3


(Homo sapiens)
BDBM50445055
PNG
(CHEMBL3098744)
Show SMILES CC(C)c1ccc(C(=O)Nc2cccc(C)n2)c(c1)C(O)=O
Show InChI InChI=1S/C17H18N2O3/c1-10(2)12-7-8-13(14(9-12)17(21)22)16(20)19-15-6-4-5-11(3)18-15/h4-10H,1-3H3,(H,21,22)(H,18,19,20)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 1.10E+3n/an/an/an/an/an/a



H. Lundbeck A/S

Curated by ChEMBL


Assay Description
Displacement of [3H]-neurotensin from sortilin (unknown origin) incubated 30 mins prior to [3H]-neurotensin addition measured after 6 hrs by scintill...


Citation and Details
More data for this
Ligand-Target Pair
Neurotensin receptor 3


(Homo sapiens)
BDBM50133196
PNG
(CHEMBL337260 | Compound KK6)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)CCCN=C(N)NC(=O)[C@@H](N)CCCCNC)C(=O)N[C@@H](CC(C)C)C(O)=O
Show InChI InChI=1S/C39H66N10O8/c1-6-24(4)32(36(54)46-30(38(56)57)21-23(2)3)47-34(52)29(22-25-14-16-26(50)17-15-25)45-35(53)31-13-10-20-49(31)37(55)28(41)12-9-19-44-39(42)48-33(51)27(40)11-7-8-18-43-5/h14-17,23-24,27-32,43,50H,6-13,18-22,40-41H2,1-5H3,(H,45,53)(H,46,54)(H,47,52)(H,56,57)(H3,42,44,48,51)/t24-,27-,28-,29-,30-,31-,32-/m0/s1
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 1.15E+3n/an/an/an/an/an/a



Medical University of South Carolina

Curated by ChEMBL


Assay Description
Evaluated for binding affinity by inhibiting binding of [125I]Tyr(3)-NT to human Neurotensin receptor 3


Citation and Details
More data for this
Ligand-Target Pair
Neurotensin receptor 3


(Homo sapiens)
BDBM50133206
PNG
(CHEMBL337644 | Compound KK1)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)CCCN=C(N)NC(=O)[C@@H](N)CCCCCN)C(=O)N[C@@H](CC(C)C)C(O)=O
Show InChI InChI=1S/C39H66N10O8/c1-5-24(4)32(36(54)46-30(38(56)57)21-23(2)3)47-34(52)29(22-25-14-16-26(50)17-15-25)45-35(53)31-13-10-20-49(31)37(55)28(42)12-9-19-44-39(43)48-33(51)27(41)11-7-6-8-18-40/h14-17,23-24,27-32,50H,5-13,18-22,40-42H2,1-4H3,(H,45,53)(H,46,54)(H,47,52)(H,56,57)(H3,43,44,48,51)/t24-,27-,28-,29-,30-,31-,32-/m0/s1
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 1.20E+3n/an/an/an/an/an/a



Medical University of South Carolina

Curated by ChEMBL


Assay Description
Evaluated for binding affinity by inhibiting binding of [125I]Tyr(3)-NT to human Neurotensin receptor 3


Citation and Details
More data for this
Ligand-Target Pair
Neurotensin receptor 3


(Homo sapiens)
BDBM50445043
PNG
(CHEMBL3098766)
Show SMILES COc1cccc(NC(=O)c2ccc(cc2C(O)=O)C(F)(F)F)n1
Show InChI InChI=1S/C15H11F3N2O4/c1-24-12-4-2-3-11(19-12)20-13(21)9-6-5-8(15(16,17)18)7-10(9)14(22)23/h2-7H,1H3,(H,22,23)(H,19,20,21)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
AffyNet 
Article
PubMed
n/an/a 1.30E+3n/an/an/an/an/an/a



H. Lundbeck A/S

Curated by ChEMBL


Assay Description
Displacement of [3H]-neurotensin from sortilin (unknown origin) incubated 30 mins prior to [3H]-neurotensin addition measured after 6 hrs by scintill...


Citation and Details
More data for this
Ligand-Target Pair
Neurotensin receptor 3


(Homo sapiens)
BDBM50445057
PNG
(CHEMBL3098742)
Show SMILES Cc1cccc(NC(=O)c2ccc(Cl)cc2C(O)=O)n1
Show InChI InChI=1S/C14H11ClN2O3/c1-8-3-2-4-12(16-8)17-13(18)10-6-5-9(15)7-11(10)14(19)20/h2-7H,1H3,(H,19,20)(H,16,17,18)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 1.40E+3n/an/an/an/an/an/a



H. Lundbeck A/S

Curated by ChEMBL


Assay Description
Displacement of [3H]-neurotensin from sortilin (unknown origin) incubated 30 mins prior to [3H]-neurotensin addition measured after 6 hrs by scintill...


Citation and Details
More data for this
Ligand-Target Pair
Neurotensin receptor 3


(Homo sapiens)
BDBM50133199
PNG
(CHEMBL339139 | Compound KK9)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)CCCN=C(N)NC(=O)[C@@H](N)CCCN)C(=O)N[C@@H](CC(C)C)C(O)=O
Show InChI InChI=1S/C37H62N10O8/c1-5-22(4)30(34(52)44-28(36(54)55)19-21(2)3)45-32(50)27(20-23-12-14-24(48)15-13-23)43-33(51)29-11-8-18-47(29)35(53)26(40)10-7-17-42-37(41)46-31(49)25(39)9-6-16-38/h12-15,21-22,25-30,48H,5-11,16-20,38-40H2,1-4H3,(H,43,51)(H,44,52)(H,45,50)(H,54,55)(H3,41,42,46,49)/t22-,25-,26-,27-,28-,29-,30-/m0/s1
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 1.40E+3n/an/an/an/an/an/a



Medical University of South Carolina

Curated by ChEMBL


Assay Description
Evaluated for binding affinity by inhibiting binding of [125I]Tyr(3)-NT to human Neurotensin receptor 3


Citation and Details
More data for this
Ligand-Target Pair
Neurotensin receptor 3


(Homo sapiens)
BDBM50445047
PNG
(CHEMBL3098760)
Show SMILES OC(=O)c1cc(Br)ccc1C(=O)Nc1cccc(Cl)n1
Show InChI InChI=1S/C13H8BrClN2O3/c14-7-4-5-8(9(6-7)13(19)20)12(18)17-11-3-1-2-10(15)16-11/h1-6H,(H,19,20)(H,16,17,18)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 1.60E+3n/an/an/an/an/an/a



H. Lundbeck A/S

Curated by ChEMBL


Assay Description
Displacement of [3H]-neurotensin from sortilin (unknown origin) incubated 30 mins prior to [3H]-neurotensin addition measured after 6 hrs by scintill...


Citation and Details
More data for this
Ligand-Target Pair
Neurotensin receptor 3


(Homo sapiens)
BDBM50133191
PNG
(CHEMBL132507 | Compound KK7)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)CCCN=C(N)NC(=O)[C@@H](N)CCCCN(C)C)C(=O)N[C@@H](CC(C)C)C(O)=O
Show InChI InChI=1S/C40H68N10O8/c1-7-25(4)33(37(55)46-31(39(57)58)22-24(2)3)47-35(53)30(23-26-15-17-27(51)18-16-26)45-36(54)32-14-11-21-50(32)38(56)29(42)13-10-19-44-40(43)48-34(52)28(41)12-8-9-20-49(5)6/h15-18,24-25,28-33,51H,7-14,19-23,41-42H2,1-6H3,(H,45,54)(H,46,55)(H,47,53)(H,57,58)(H3,43,44,48,52)/t25-,28-,29-,30-,31-,32-,33-/m0/s1
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 1.62E+3n/an/an/an/an/an/a



Medical University of South Carolina

Curated by ChEMBL


Assay Description
Evaluated for binding affinity by inhibiting binding of [125I]Tyr(3)-NT to human Neurotensin receptor 3


Citation and Details
More data for this
Ligand-Target Pair
Neurotensin receptor 3


(Homo sapiens)
BDBM50445053
PNG
(CHEMBL3098746)
Show SMILES Cc1cccc(NC(=O)c2ccc(cc2C(O)=O)[N+]([O-])=O)n1
Show InChI InChI=1S/C14H11N3O5/c1-8-3-2-4-12(15-8)16-13(18)10-6-5-9(17(21)22)7-11(10)14(19)20/h2-7H,1H3,(H,19,20)(H,15,16,18)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
AffyNet 
Article
PubMed
n/an/a 1.70E+3n/an/an/an/an/an/a



H. Lundbeck A/S

Curated by ChEMBL


Assay Description
Displacement of [3H]-neurotensin from sortilin (unknown origin) incubated 30 mins prior to [3H]-neurotensin addition measured after 6 hrs by scintill...


Citation and Details
More data for this
Ligand-Target Pair
Neurotensin receptor 3


(Homo sapiens)
BDBM50133204
PNG
(CHEMBL132409 | Compound KK15)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)CCCN=C(N)NC(=O)[C@@H](N)CCCN=C(N)N)C(=O)N[C@@H](CC(C)C)C(O)=O
Show InChI InChI=1S/C38H64N12O8/c1-5-22(4)30(34(55)47-28(36(57)58)19-21(2)3)48-32(53)27(20-23-12-14-24(51)15-13-23)46-33(54)29-11-8-18-50(29)35(56)26(40)10-7-17-45-38(43)49-31(52)25(39)9-6-16-44-37(41)42/h12-15,21-22,25-30,51H,5-11,16-20,39-40H2,1-4H3,(H,46,54)(H,47,55)(H,48,53)(H,57,58)(H4,41,42,44)(H3,43,45,49,52)/t22-,25-,26-,27-,28-,29-,30-/m0/s1
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 1.74E+3n/an/an/an/an/an/a



Medical University of South Carolina

Curated by ChEMBL


Assay Description
Evaluated for binding affinity by inhibiting binding of [125I]Tyr(3)-NT to human Neurotensin receptor 3


Citation and Details
More data for this
Ligand-Target Pair
Neurotensin receptor 3


(Homo sapiens)
BDBM50445045
PNG
(CHEMBL3098764)
Show SMILES Cc1cc(NC(=O)c2ccc(Br)cc2C(O)=O)ccn1
Show InChI InChI=1S/C14H11BrN2O3/c1-8-6-10(4-5-16-8)17-13(18)11-3-2-9(15)7-12(11)14(19)20/h2-7H,1H3,(H,19,20)(H,16,17,18)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
AffyNet 
Article
PubMed
n/an/a 1.80E+3n/an/an/an/an/an/a



H. Lundbeck A/S

Curated by ChEMBL


Assay Description
Displacement of [3H]-neurotensin from sortilin (unknown origin) incubated 30 mins prior to [3H]-neurotensin addition measured after 6 hrs by scintill...


Citation and Details
More data for this
Ligand-Target Pair
Neurotensin receptor 3


(Homo sapiens)
BDBM50133200
PNG
(CHEMBL129953 | Compound KK12)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)CCCN=C(N)NC(=O)[C@@H](N)CCC[N+](C)(C)C)C(=O)N[C@@H](CC(C)C)C(O)=O
Show InChI InChI=1S/C40H68N10O8/c1-8-25(4)33(37(55)46-31(39(57)58)22-24(2)3)47-35(53)30(23-26-15-17-27(51)18-16-26)45-36(54)32-14-10-20-49(32)38(56)29(42)12-9-19-44-40(43)48-34(52)28(41)13-11-21-50(5,6)7/h15-18,24-25,28-33H,8-14,19-23,41-42H2,1-7H3,(H7-,43,44,45,46,47,48,51,52,53,54,55,57,58)/p+1/t25-,28-,29-,30-,31-,32-,33-/m0/s1
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 2.00E+3n/an/an/an/an/an/a



Medical University of South Carolina

Curated by ChEMBL


Assay Description
Evaluated for binding affinity by inhibiting binding of [125I]Tyr(3)-NT to human Neurotensin receptor 3


Citation and Details
More data for this
Ligand-Target Pair
Neurotensin receptor 3


(Homo sapiens)
BDBM50445046
PNG
(CHEMBL3098761)
Show SMILES Cc1ccnc(NC(=O)c2ccc(Br)cc2C(O)=O)c1
Show InChI InChI=1S/C14H11BrN2O3/c1-8-4-5-16-12(6-8)17-13(18)10-3-2-9(15)7-11(10)14(19)20/h2-7H,1H3,(H,19,20)(H,16,17,18)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 2.40E+3n/an/an/an/an/an/a



H. Lundbeck A/S

Curated by ChEMBL


Assay Description
Displacement of [3H]-neurotensin from sortilin (unknown origin) incubated 30 mins prior to [3H]-neurotensin addition measured after 6 hrs by scintill...


Citation and Details
More data for this
Ligand-Target Pair
Neurotensin receptor 3


(Homo sapiens)
BDBM50445050
PNG
(CHEMBL3098753)
Show SMILES Cc1cccc(NC(=O)c2cc(C)c(C)cc2C(O)=O)n1
Show InChI InChI=1S/C16H16N2O3/c1-9-7-12(13(16(20)21)8-10(9)2)15(19)18-14-6-4-5-11(3)17-14/h4-8H,1-3H3,(H,20,21)(H,17,18,19)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 3.40E+3n/an/an/an/an/an/a



H. Lundbeck A/S

Curated by ChEMBL


Assay Description
Displacement of [3H]-neurotensin from sortilin (unknown origin) incubated 30 mins prior to [3H]-neurotensin addition measured after 6 hrs by scintill...


Citation and Details
More data for this
Ligand-Target Pair
Neurotensin receptor 3


(Homo sapiens)
BDBM50133205
PNG
(CHEMBL133798 | Compound KK8)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)CCCN=C(N)NC(=O)[C@@H](N)CCCC[N+](C)(C)C)C(=O)N[C@@H](CC(C)C)C(O)=O
Show InChI InChI=1S/C41H70N10O8/c1-8-26(4)34(38(56)47-32(40(58)59)23-25(2)3)48-36(54)31(24-27-16-18-28(52)19-17-27)46-37(55)33-15-12-21-50(33)39(57)30(43)14-11-20-45-41(44)49-35(53)29(42)13-9-10-22-51(5,6)7/h16-19,25-26,29-34H,8-15,20-24,42-43H2,1-7H3,(H7-,44,45,46,47,48,49,52,53,54,55,56,58,59)/p+1/t26-,29-,30-,31-,32-,33-,34-/m0/s1
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 3.50E+3n/an/an/an/an/an/a



Medical University of South Carolina

Curated by ChEMBL


Assay Description
Evaluated for binding affinity by inhibiting binding of [125I]Tyr(3)-NT to human Neurotensin receptor 3


Citation and Details
More data for this
Ligand-Target Pair
Neurotensin receptor 3


(Homo sapiens)
BDBM50445048
PNG
(CHEMBL3098759)
Show SMILES OC(=O)c1cc(Br)ccc1C(=O)Nc1ccccn1
Show InChI InChI=1S/C13H9BrN2O3/c14-8-4-5-9(10(7-8)13(18)19)12(17)16-11-3-1-2-6-15-11/h1-7H,(H,18,19)(H,15,16,17)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 3.60E+3n/an/an/an/an/an/a



H. Lundbeck A/S

Curated by ChEMBL


Assay Description
Displacement of [3H]-neurotensin from sortilin (unknown origin) incubated 30 mins prior to [3H]-neurotensin addition measured after 6 hrs by scintill...


Citation and Details
More data for this
Ligand-Target Pair
Neurotensin receptor 3


(Homo sapiens)
BDBM50133197
PNG
(CHEMBL335846 | Compound KK13)
Show SMILES CC(C)C[C@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)CCCN=C(N)NC(=O)[C@@H](N)CCCCCN)C(C)(C)C)C(O)=O
Show InChI InChI=1S/C39H66N10O8/c1-23(2)21-29(37(56)57)46-35(54)31(39(3,4)5)47-33(52)28(22-24-14-16-25(50)17-15-24)45-34(53)30-13-10-20-49(30)36(55)27(42)12-9-19-44-38(43)48-32(51)26(41)11-7-6-8-18-40/h14-17,23,26-31,50H,6-13,18-22,40-42H2,1-5H3,(H,45,53)(H,46,54)(H,47,52)(H,56,57)(H3,43,44,48,51)/t26-,27-,28-,29-,30-,31+/m0/s1
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 4.00E+3n/an/an/an/an/an/a



Medical University of South Carolina

Curated by ChEMBL


Assay Description
Evaluated for binding affinity by inhibiting binding of [125I]Tyr(3)-NT to human Neurotensin receptor 3


Citation and Details
More data for this
Ligand-Target Pair
Neurotensin receptor 3


(Homo sapiens)
BDBM50445039
PNG
(CHEMBL3098769)
Show SMILES CC(C)C[C@H](NCc1c(O)ccc2c(C)cc(=O)oc12)C(O)=O
Show InChI InChI=1S/C17H21NO5/c1-9(2)6-13(17(21)22)18-8-12-14(19)5-4-11-10(3)7-15(20)23-16(11)12/h4-5,7,9,13,18-19H,6,8H2,1-3H3,(H,21,22)/t13-/m0/s1
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
PDB
UniChem
AffyNet 
PDB
Article
PubMed
n/an/a 4.00E+3n/an/an/an/an/an/a



H. Lundbeck A/S

Curated by ChEMBL


Assay Description
Displacement of [3H]-neurotensin from sortilin (unknown origin) incubated 30 mins prior to [3H]-neurotensin addition measured after 6 hrs by scintill...


Citation and Details
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Neurotensin receptor 3


(Homo sapiens)
BDBM50445049
PNG
(CHEMBL3098758)
Show SMILES Cc1cccc(NC(=O)c2ccc(Br)cc2C(O)=O)c1
Show InChI InChI=1S/C15H12BrNO3/c1-9-3-2-4-11(7-9)17-14(18)12-6-5-10(16)8-13(12)15(19)20/h2-8H,1H3,(H,17,18)(H,19,20)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
AffyNet 
Article
PubMed
n/an/a 5.20E+3n/an/an/an/an/an/a



H. Lundbeck A/S

Curated by ChEMBL


Assay Description
Displacement of [3H]-neurotensin from sortilin (unknown origin) incubated 30 mins prior to [3H]-neurotensin addition measured after 6 hrs by scintill...


Citation and Details
More data for this
Ligand-Target Pair
Neurotensin receptor 3


(Homo sapiens)
BDBM50445056
PNG
(CHEMBL3098743)
Show SMILES Cc1ccc(C(=O)Nc2cccc(C)n2)c(c1)C(O)=O
Show InChI InChI=1S/C15H14N2O3/c1-9-6-7-11(12(8-9)15(19)20)14(18)17-13-5-3-4-10(2)16-13/h3-8H,1-2H3,(H,19,20)(H,16,17,18)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 6.40E+3n/an/an/an/an/an/a



H. Lundbeck A/S

Curated by ChEMBL


Assay Description
Displacement of [3H]-neurotensin from sortilin (unknown origin) incubated 30 mins prior to [3H]-neurotensin addition measured after 6 hrs by scintill...


Citation and Details
More data for this
Ligand-Target Pair
Neurotensin receptor 3


(Homo sapiens)
BDBM50445040
PNG
(CHEMBL3098751)
Show SMILES Cc1cccc(NC(=O)c2cc(ccc2C(O)=O)C(F)(F)F)n1
Show InChI InChI=1S/C15H11F3N2O3/c1-8-3-2-4-12(19-8)20-13(21)11-7-9(15(16,17)18)5-6-10(11)14(22)23/h2-7H,1H3,(H,22,23)(H,19,20,21)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 9.10E+3n/an/an/an/an/an/a



H. Lundbeck A/S

Curated by ChEMBL


Assay Description
Displacement of [3H]-neurotensin from sortilin (unknown origin) incubated 30 mins prior to [3H]-neurotensin addition measured after 6 hrs by scintill...


Citation and Details
More data for this
Ligand-Target Pair
Neurotensin receptor 3


(Homo sapiens)
BDBM50445052
PNG
(CHEMBL3098748)
Show SMILES Cc1cccc(NC(=O)c2cc(Br)ccc2C(O)=O)n1
Show InChI InChI=1S/C14H11BrN2O3/c1-8-3-2-4-12(16-8)17-13(18)11-7-9(15)5-6-10(11)14(19)20/h2-7H,1H3,(H,19,20)(H,16,17,18)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 1.20E+4n/an/an/an/an/an/a



H. Lundbeck A/S

Curated by ChEMBL


Assay Description
Displacement of [3H]-neurotensin from sortilin (unknown origin) incubated 30 mins prior to [3H]-neurotensin addition measured after 6 hrs by scintill...


Citation and Details
More data for this
Ligand-Target Pair
Neurotensin receptor 3


(Homo sapiens)
BDBM50133189
PNG
(CHEMBL435199 | Compound KK14)
Show SMILES CC(C)C[C@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)CCCN=C(N)NC(=O)[C@@H](N)CCCCCN)C(C)(C)C)C(O)=O
Show InChI InChI=1S/C41H67N11O7/c1-24(2)21-31(39(58)59)49-37(56)33(41(3,4)5)50-35(54)30(22-25-23-47-29-16-9-8-13-26(25)29)48-36(55)32-17-12-20-52(32)38(57)28(44)15-11-19-46-40(45)51-34(53)27(43)14-7-6-10-18-42/h8-9,13,16,23-24,27-28,30-33,47H,6-7,10-12,14-15,17-22,42-44H2,1-5H3,(H,48,55)(H,49,56)(H,50,54)(H,58,59)(H3,45,46,51,53)/t27-,28-,30-,31-,32-,33+/m0/s1
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 5.37E+4n/an/an/an/an/an/a



Medical University of South Carolina

Curated by ChEMBL


Assay Description
Evaluated for binding affinity by inhibiting binding of [125I]Tyr(3)-NT to human Neurotensin receptor 3


Citation and Details
More data for this
Ligand-Target Pair