BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 54 hits Enz. Inhib. hit(s) with Target = 'Nicotinic acetylcholine receptor alpha9/alpha10' AND taxid = 10116   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Nicotinic acetylcholine receptor alpha9/alpha10


(Rattus norvegicus)
BDBM50287851
PNG
((S)-2-(3-Fluoro-phenoxymethyl)-azetidine | CHEMBL3...)
Show SMILES Fc1cccc(OC[C@@H]2CCN2)c1
Show InChI InChI=1S/C10H12FNO/c11-8-2-1-3-10(6-8)13-7-9-4-5-12-9/h1-3,6,9,12H,4-5,7H2/t9-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
3.10n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]-Cytisine as radioligand in whole rat brain


Bioorg Med Chem Lett 6: 2283-2288 (1996)

More data for this
Ligand-Target Pair
Nicotinic acetylcholine receptor alpha9/alpha10


(Rattus norvegicus)
BDBM50287814
PNG
((S)-2-(3-Fluoro-phenoxymethyl)-1-methyl-pyrrolidin...)
Show SMILES CN1CCC[C@H]1COc1cccc(F)c1
Show InChI InChI=1S/C12H16FNO/c1-14-7-3-5-11(14)9-15-12-6-2-4-10(13)8-12/h2,4,6,8,11H,3,5,7,9H2,1H3/t11-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
5n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]-Cytisine as radioligand in whole rat brain


Bioorg Med Chem Lett 6: 2283-2288 (1996)

More data for this
Ligand-Target Pair
Nicotinic acetylcholine receptor alpha9/alpha10


(Rattus norvegicus)
BDBM50287829
PNG
((R)-2-(3-Fluoro-phenoxymethyl)-pyrrolidine | CHEMB...)
Show SMILES Fc1cccc(OC[C@H]2CCCN2)c1
Show InChI InChI=1S/C11H14FNO/c12-9-3-1-5-11(7-9)14-8-10-4-2-6-13-10/h1,3,5,7,10,13H,2,4,6,8H2/t10-/m1/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
13n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]-Cytisine as radioligand in whole rat brain


Bioorg Med Chem Lett 6: 2283-2288 (1996)

More data for this
Ligand-Target Pair
Nicotinic acetylcholine receptor alpha9/alpha10


(Rattus norvegicus)
BDBM50287812
PNG
((S)-2-(3-Fluoro-phenoxymethyl)-pyrrolidine | CHEMB...)
Show SMILES Fc1cccc(OC[C@@H]2CCCN2)c1
Show InChI InChI=1S/C11H14FNO/c12-9-3-1-5-11(7-9)14-8-10-4-2-6-13-10/h1,3,5,7,10,13H,2,4,6,8H2/t10-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
Article
14.3n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]-Cytisine as radioligand in whole rat brain


Bioorg Med Chem Lett 6: 2283-2288 (1996)

More data for this
Ligand-Target Pair
Nicotinic acetylcholine receptor alpha9/alpha10


(Rattus norvegicus)
BDBM50287821
PNG
((S)-2-(3-Fluoro-phenoxymethyl)-1-methyl-azetidine ...)
Show SMILES CN1CC[C@H]1COc1cccc(F)c1
Show InChI InChI=1S/C11H14FNO/c1-13-6-5-10(13)8-14-11-4-2-3-9(12)7-11/h2-4,7,10H,5-6,8H2,1H3/t10-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
14.4n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]-Cytisine as radioligand in whole rat brain


Bioorg Med Chem Lett 6: 2283-2288 (1996)

More data for this
Ligand-Target Pair
Nicotinic acetylcholine receptor alpha9/alpha10


(Rattus norvegicus)
BDBM50287838
PNG
((S)-2-(3,4-Difluoro-phenoxymethyl)-pyrrolidine | C...)
Show SMILES Fc1ccc(OC[C@@H]2CCCN2)cc1F
Show InChI InChI=1S/C11H13F2NO/c12-10-4-3-9(6-11(10)13)15-7-8-2-1-5-14-8/h3-4,6,8,14H,1-2,5,7H2/t8-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
17.3n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]-Cytisine as radioligand in whole rat brain


Bioorg Med Chem Lett 6: 2283-2288 (1996)

More data for this
Ligand-Target Pair
Nicotinic acetylcholine receptor alpha9/alpha10


(Rattus norvegicus)
BDBM50287848
PNG
((S)-2-(3,4-Difluoro-phenoxymethyl)-1-methyl-pyrrol...)
Show SMILES CN1CCC[C@H]1COc1ccc(F)c(F)c1
Show InChI InChI=1S/C12H15F2NO/c1-15-6-2-3-9(15)8-16-10-4-5-11(13)12(14)7-10/h4-5,7,9H,2-3,6,8H2,1H3/t9-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
17.6n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]-Cytisine as radioligand in whole rat brain


Bioorg Med Chem Lett 6: 2283-2288 (1996)

More data for this
Ligand-Target Pair
Nicotinic acetylcholine receptor alpha9/alpha10


(Rattus norvegicus)
BDBM50287816
PNG
((S)-2-(3,5-Difluoro-phenoxymethyl)-pyrrolidine | C...)
Show SMILES Fc1cc(F)cc(OC[C@@H]2CCCN2)c1
Show InChI InChI=1S/C11H13F2NO/c12-8-4-9(13)6-11(5-8)15-7-10-2-1-3-14-10/h4-6,10,14H,1-3,7H2/t10-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
18n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]-Cytisine as radioligand in whole rat brain


Bioorg Med Chem Lett 6: 2283-2288 (1996)

More data for this
Ligand-Target Pair
Nicotinic acetylcholine receptor alpha9/alpha10


(Rattus norvegicus)
BDBM50287834
PNG
(3-((S)-1-Pyrrolidin-2-ylmethoxy)-benzonitrile | CH...)
Show SMILES N#Cc1cccc(OC[C@@H]2CCCN2)c1
Show InChI InChI=1S/C12H14N2O/c13-8-10-3-1-5-12(7-10)15-9-11-4-2-6-14-11/h1,3,5,7,11,14H,2,4,6,9H2/t11-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
Article
18n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]-Cytisine as radioligand in whole rat brain


Bioorg Med Chem Lett 6: 2283-2288 (1996)

More data for this
Ligand-Target Pair
Nicotinic acetylcholine receptor alpha9/alpha10


(Rattus norvegicus)
BDBM50287849
PNG
((S)-2-(3,5-Difluoro-phenoxymethyl)-1-methyl-pyrrol...)
Show SMILES CN1CCC[C@H]1COc1cc(F)cc(F)c1
Show InChI InChI=1S/C12H15F2NO/c1-15-4-2-3-11(15)8-16-12-6-9(13)5-10(14)7-12/h5-7,11H,2-4,8H2,1H3/t11-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
19.3n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]-Cytisine as radioligand in whole rat brain


Bioorg Med Chem Lett 6: 2283-2288 (1996)

More data for this
Ligand-Target Pair
Nicotinic acetylcholine receptor alpha9/alpha10


(Rattus norvegicus)
BDBM50287852
PNG
((S)-2-(3-Chloro-phenoxymethyl)-1-methyl-pyrrolidin...)
Show SMILES CN1CCC[C@H]1COc1cccc(Cl)c1
Show InChI InChI=1S/C12H16ClNO/c1-14-7-3-5-11(14)9-15-12-6-2-4-10(13)8-12/h2,4,6,8,11H,3,5,7,9H2,1H3/t11-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
Article
37n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]-Cytisine as radioligand in whole rat brain


Bioorg Med Chem Lett 6: 2283-2288 (1996)

More data for this
Ligand-Target Pair
Nicotinic acetylcholine receptor alpha9/alpha10


(Rattus norvegicus)
BDBM50287824
PNG
((S)-1-Methyl-2-phenoxymethyl-pyrrolidine | CHEMBL7...)
Show SMILES CN1CCC[C@H]1COc1ccccc1
Show InChI InChI=1S/C12H17NO/c1-13-9-5-6-11(13)10-14-12-7-3-2-4-8-12/h2-4,7-8,11H,5-6,9-10H2,1H3/t11-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
42n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]-Cytisine as radioligand in whole rat brain


Bioorg Med Chem Lett 6: 2283-2288 (1996)

More data for this
Ligand-Target Pair
Nicotinic acetylcholine receptor alpha9/alpha10


(Rattus norvegicus)
BDBM50287820
PNG
(3-((S)-1-Methyl-pyrrolidin-2-ylmethoxy)-benzonitri...)
Show SMILES CN1CCC[C@H]1COc1cccc(c1)C#N
Show InChI InChI=1S/C13H16N2O/c1-15-7-3-5-12(15)10-16-13-6-2-4-11(8-13)9-14/h2,4,6,8,12H,3,5,7,10H2,1H3/t12-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
51n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]-Cytisine as radioligand in whole rat brain


Bioorg Med Chem Lett 6: 2283-2288 (1996)

More data for this
Ligand-Target Pair
Nicotinic acetylcholine receptor alpha9/alpha10


(Rattus norvegicus)
BDBM50287843
PNG
((S)-2-Phenoxymethyl-azetidine | CHEMBL72031)
Show SMILES C(Oc1ccccc1)[C@@H]1CCN1
Show InChI InChI=1S/C10H13NO/c1-2-4-10(5-3-1)12-8-9-6-7-11-9/h1-5,9,11H,6-8H2/t9-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
52n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]-Cytisine as radioligand in whole rat brain


Bioorg Med Chem Lett 6: 2283-2288 (1996)

More data for this
Ligand-Target Pair
Nicotinic acetylcholine receptor alpha9/alpha10


(Rattus norvegicus)
BDBM50287825
PNG
((S)-2-(2,3-Difluoro-phenoxymethyl)-1-methyl-pyrrol...)
Show SMILES CN1CCC[C@H]1COc1cccc(F)c1F
Show InChI InChI=1S/C12H15F2NO/c1-15-7-3-4-9(15)8-16-11-6-2-5-10(13)12(11)14/h2,5-6,9H,3-4,7-8H2,1H3/t9-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
69n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]-Cytisine as radioligand in whole rat brain


Bioorg Med Chem Lett 6: 2283-2288 (1996)

More data for this
Ligand-Target Pair
Nicotinic acetylcholine receptor alpha9/alpha10


(Rattus norvegicus)
BDBM50287846
PNG
((S)-2-(2,3-Difluoro-phenoxymethyl)-pyrrolidine | C...)
Show SMILES Fc1cccc(OC[C@@H]2CCCN2)c1F
Show InChI InChI=1S/C11H13F2NO/c12-9-4-1-5-10(11(9)13)15-7-8-3-2-6-14-8/h1,4-5,8,14H,2-3,6-7H2/t8-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
77n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]-Cytisine as radioligand in whole rat brain


Bioorg Med Chem Lett 6: 2283-2288 (1996)

More data for this
Ligand-Target Pair
Nicotinic acetylcholine receptor alpha9/alpha10


(Rattus norvegicus)
BDBM50287854
PNG
((R)-2-(3-Fluoro-phenoxymethyl)-1-methyl-pyrrolidin...)
Show SMILES CN1CCC[C@@H]1COc1cccc(F)c1
Show InChI InChI=1S/C12H16FNO/c1-14-7-3-5-11(14)9-15-12-6-2-4-10(13)8-12/h2,4,6,8,11H,3,5,7,9H2,1H3/t11-/m1/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
78n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]-Cytisine as radioligand in whole rat brain


Bioorg Med Chem Lett 6: 2283-2288 (1996)

More data for this
Ligand-Target Pair
Nicotinic acetylcholine receptor alpha9/alpha10


(Rattus norvegicus)
BDBM50287842
PNG
((S)-1-Methyl-2-phenoxymethyl-azetidine | CHEMBL754...)
Show SMILES CN1CC[C@H]1COc1ccccc1
Show InChI InChI=1S/C11H15NO/c1-12-8-7-10(12)9-13-11-5-3-2-4-6-11/h2-6,10H,7-9H2,1H3/t10-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
101n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]-Cytisine as radioligand in whole rat brain


Bioorg Med Chem Lett 6: 2283-2288 (1996)

More data for this
Ligand-Target Pair
Nicotinic acetylcholine receptor alpha9/alpha10


(Rattus norvegicus)
BDBM50287830
PNG
((R)-2-Phenoxymethyl-pyrrolidine | CHEMBL73784)
Show SMILES C(Oc1ccccc1)[C@H]1CCCN1
Show InChI InChI=1S/C11H15NO/c1-2-6-11(7-3-1)13-9-10-5-4-8-12-10/h1-3,6-7,10,12H,4-5,8-9H2/t10-/m1/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
Article
107n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]-Cytisine as radioligand in whole rat brain


Bioorg Med Chem Lett 6: 2283-2288 (1996)

More data for this
Ligand-Target Pair
Nicotinic acetylcholine receptor alpha9/alpha10


(Rattus norvegicus)
BDBM50287844
PNG
((S)-2-(3,4-Dichloro-phenoxymethyl)-1-methyl-pyrrol...)
Show SMILES CN1CCC[C@H]1COc1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C12H15Cl2NO/c1-15-6-2-3-9(15)8-16-10-4-5-11(13)12(14)7-10/h4-5,7,9H,2-3,6,8H2,1H3/t9-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
Article
112n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]-Cytisine as radioligand in whole rat brain


Bioorg Med Chem Lett 6: 2283-2288 (1996)

More data for this
Ligand-Target Pair
Nicotinic acetylcholine receptor alpha9/alpha10


(Rattus norvegicus)
BDBM50287855
PNG
(3-((S)-1-Pyrrolidin-2-ylmethoxy)-benzamide | CHEMB...)
Show SMILES NC(=O)c1cccc(OC[C@@H]2CCCN2)c1
Show InChI InChI=1S/C12H16N2O2/c13-12(15)9-3-1-5-11(7-9)16-8-10-4-2-6-14-10/h1,3,5,7,10,14H,2,4,6,8H2,(H2,13,15)/t10-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
AffyNet 
Article
136n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]-Cytisine as radioligand in whole rat brain


Bioorg Med Chem Lett 6: 2283-2288 (1996)

More data for this
Ligand-Target Pair
Nicotinic acetylcholine receptor alpha9/alpha10


(Rattus norvegicus)
BDBM50287835
PNG
((S)-2-(Benzo[1,3]dioxol-5-yloxymethyl)-1-methyl-py...)
Show SMILES CN1CCC[C@H]1COc1ccc2OCOc2c1
Show InChI InChI=1S/C13H17NO3/c1-14-6-2-3-10(14)8-15-11-4-5-12-13(7-11)17-9-16-12/h4-5,7,10H,2-3,6,8-9H2,1H3/t10-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
AffyNet 
Article
169n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]-Cytisine as radioligand in whole rat brain


Bioorg Med Chem Lett 6: 2283-2288 (1996)

More data for this
Ligand-Target Pair
Nicotinic acetylcholine receptor alpha9/alpha10


(Rattus norvegicus)
BDBM50287850
PNG
((S)-2-(3-Methoxy-phenoxymethyl)-1-methyl-pyrrolidi...)
Show SMILES COc1cccc(OC[C@@H]2CCCN2C)c1
Show InChI InChI=1S/C13H19NO2/c1-14-8-4-5-11(14)10-16-13-7-3-6-12(9-13)15-2/h3,6-7,9,11H,4-5,8,10H2,1-2H3/t11-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
175n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]-Cytisine as radioligand in whole rat brain


Bioorg Med Chem Lett 6: 2283-2288 (1996)

More data for this
Ligand-Target Pair
Nicotinic acetylcholine receptor alpha9/alpha10


(Rattus norvegicus)
BDBM50287813
PNG
((S)-2-Phenoxymethyl-pyrrolidine | CHEMBL418900)
Show SMILES C(Oc1ccccc1)[C@@H]1CCCN1
Show InChI InChI=1S/C11H15NO/c1-2-6-11(7-3-1)13-9-10-5-4-8-12-10/h1-3,6-7,10,12H,4-5,8-9H2/t10-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
Article
195n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]-Cytisine as radioligand in whole rat brain


Bioorg Med Chem Lett 6: 2283-2288 (1996)

More data for this
Ligand-Target Pair
Nicotinic acetylcholine receptor alpha9/alpha10


(Rattus norvegicus)
BDBM50287826
PNG
((R)-1-Methyl-2-phenoxymethyl-pyrrolidine | CHEMBL7...)
Show SMILES CN1CCC[C@@H]1COc1ccccc1
Show InChI InChI=1S/C12H17NO/c1-13-9-5-6-11(13)10-14-12-7-3-2-4-8-12/h2-4,7-8,11H,5-6,9-10H2,1H3/t11-/m1/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
204n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]-Cytisine as radioligand in whole rat brain


Bioorg Med Chem Lett 6: 2283-2288 (1996)

More data for this
Ligand-Target Pair
Nicotinic acetylcholine receptor alpha9/alpha10


(Rattus norvegicus)
BDBM50287828
PNG
((S)-2-(2-Fluoro-phenoxymethyl)-1-methyl-pyrrolidin...)
Show SMILES CN1CCC[C@H]1COc1ccccc1F
Show InChI InChI=1S/C12H16FNO/c1-14-8-4-5-10(14)9-15-12-7-3-2-6-11(12)13/h2-3,6-7,10H,4-5,8-9H2,1H3/t10-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
304n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]-Cytisine as radioligand in whole rat brain


Bioorg Med Chem Lett 6: 2283-2288 (1996)

More data for this
Ligand-Target Pair
Nicotinic acetylcholine receptor alpha9/alpha10


(Rattus norvegicus)
BDBM50287832
PNG
(6-((S)-1-Methyl-pyrrolidin-2-ylmethoxy)-3,3-dioxo-...)
Show SMILES CN1CCC[C@H]1COc1ccc2c(OC(=O)S2(=O)=O)c1
Show InChI InChI=1S/C13H15NO5S/c1-14-6-2-3-9(14)8-18-10-4-5-12-11(7-10)19-13(15)20(12,16)17/h4-5,7,9H,2-3,6,8H2,1H3/t9-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
AffyNet 
Article
339n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]-Cytisine as radioligand in whole rat brain


Bioorg Med Chem Lett 6: 2283-2288 (1996)

More data for this
Ligand-Target Pair
Nicotinic acetylcholine receptor alpha9/alpha10


(Rattus norvegicus)
BDBM50287819
PNG
((S)-2-(3-Methoxy-phenoxymethyl)-pyrrolidine | CHEM...)
Show SMILES COc1cccc(OC[C@@H]2CCCN2)c1
Show InChI InChI=1S/C12H17NO2/c1-14-11-5-2-6-12(8-11)15-9-10-4-3-7-13-10/h2,5-6,8,10,13H,3-4,7,9H2,1H3/t10-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
468n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]-Cytisine as radioligand in whole rat brain


Bioorg Med Chem Lett 6: 2283-2288 (1996)

More data for this
Ligand-Target Pair
Nicotinic acetylcholine receptor alpha9/alpha10


(Rattus norvegicus)
BDBM50287840
PNG
((S)-2-(3-Trifluoromethyl-phenoxymethyl)-pyrrolidin...)
Show SMILES FC(F)(F)c1cccc(OC[C@@H]2CCCN2)c1
Show InChI InChI=1S/C12H14F3NO/c13-12(14,15)9-3-1-5-11(7-9)17-8-10-4-2-6-16-10/h1,3,5,7,10,16H,2,4,6,8H2/t10-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
523n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]-Cytisine as radioligand in whole rat brain


Bioorg Med Chem Lett 6: 2283-2288 (1996)

More data for this
Ligand-Target Pair
Nicotinic acetylcholine receptor alpha9/alpha10


(Rattus norvegicus)
BDBM50287837
PNG
((S)-1-Methyl-2-(3-trifluoromethyl-phenoxymethyl)-p...)
Show SMILES CN1CCC[C@H]1COc1cccc(c1)C(F)(F)F
Show InChI InChI=1S/C13H16F3NO/c1-17-7-3-5-11(17)9-18-12-6-2-4-10(8-12)13(14,15)16/h2,4,6,8,11H,3,5,7,9H2,1H3/t11-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
557n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]-Cytisine as radioligand in whole rat brain


Bioorg Med Chem Lett 6: 2283-2288 (1996)

More data for this
Ligand-Target Pair
Nicotinic acetylcholine receptor alpha9/alpha10


(Rattus norvegicus)
BDBM50287827
PNG
((S)-1-Methyl-2-(naphthalen-1-yloxymethyl)-pyrrolid...)
Show SMILES CN1CCC[C@H]1COc1cccc2ccccc12
Show InChI InChI=1S/C16H19NO/c1-17-11-5-8-14(17)12-18-16-10-4-7-13-6-2-3-9-15(13)16/h2-4,6-7,9-10,14H,5,8,11-12H2,1H3/t14-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
592n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]-Cytisine as radioligand in whole rat brain


Bioorg Med Chem Lett 6: 2283-2288 (1996)

More data for this
Ligand-Target Pair
Nicotinic acetylcholine receptor alpha9/alpha10


(Rattus norvegicus)
BDBM50287845
PNG
((S)-2-(4-Chloro-phenoxymethyl)-1-methyl-pyrrolidin...)
Show SMILES CN1CCC[C@H]1COc1ccc(Cl)cc1
Show InChI InChI=1S/C12H16ClNO/c1-14-8-2-3-11(14)9-15-12-6-4-10(13)5-7-12/h4-7,11H,2-3,8-9H2,1H3/t11-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
603n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]-Cytisine as radioligand in whole rat brain


Bioorg Med Chem Lett 6: 2283-2288 (1996)

More data for this
Ligand-Target Pair
Nicotinic acetylcholine receptor alpha9/alpha10


(Rattus norvegicus)
BDBM50287818
PNG
(((S)-2-Phenoxymethyl-pyrrolidin-1-yl)-acetonitrile...)
Show SMILES N#CCN1CCC[C@H]1COc1ccccc1
Show InChI InChI=1S/C13H16N2O/c14-8-10-15-9-4-5-12(15)11-16-13-6-2-1-3-7-13/h1-3,6-7,12H,4-5,9-11H2/t12-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
1.06E+3n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]-Cytisine as radioligand in whole rat brain


Bioorg Med Chem Lett 6: 2283-2288 (1996)

More data for this
Ligand-Target Pair
Nicotinic acetylcholine receptor alpha9/alpha10


(Rattus norvegicus)
BDBM50287853
PNG
((S)-2-(3-Fluoro-phenylsulfanylmethyl)-1-methyl-pyr...)
Show SMILES CN1CCC[C@H]1CSc1cccc(F)c1
Show InChI InChI=1S/C12H16FNS/c1-14-7-3-5-11(14)9-15-12-6-2-4-10(13)8-12/h2,4,6,8,11H,3,5,7,9H2,1H3/t11-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
1.19E+3n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]-Cytisine as radioligand in whole rat brain


Bioorg Med Chem Lett 6: 2283-2288 (1996)

More data for this
Ligand-Target Pair
Nicotinic acetylcholine receptor alpha9/alpha10


(Rattus norvegicus)
BDBM50366779
PNG
(METHYLLYCACONITINE)
Show SMILES CCN1C[C@]2(COC(=O)c3ccccc3-n3c(O)cc(C)c3O)CC[C@H](OC)[C@@]34[C@@H]5C[C@H]6[C@H](OC)[C@@H]5[C@](O)(C[C@@H]6OC)[C@](O)([C@@H](OC)[C@H]23)[C@H]14
Show InChI InChI=1S/C37H50N2O10/c1-7-38-17-34(18-49-32(42)20-10-8-9-11-23(20)39-26(40)14-19(2)31(39)41)13-12-25(46-4)36-22-15-21-24(45-3)16-35(43,27(22)28(21)47-5)37(44,33(36)38)30(48-6)29(34)36/h8-11,14,21-22,24-25,27-30,33,40-41,43-44H,7,12-13,15-18H2,1-6H3/t21-,22-,24+,25+,27-,28+,29-,30+,33-,34+,35-,36+,37+/m1/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
1.30E+3n/an/an/an/an/an/an/an/a



Ohio University

Curated by ChEMBL


Assay Description
Binding affinity towards alpha3-beta4 neuronal nicotinic acetylcholine receptor


Bioorg Med Chem Lett 14: 3739-42 (2004)

More data for this
Ligand-Target Pair
Nicotinic acetylcholine receptor alpha9/alpha10


(Rattus norvegicus)
BDBM50287857
PNG
((S)-2-(7-Chloro-indan-4-yloxymethyl)-1-methyl-pyrr...)
Show SMILES CN1CCC[C@H]1COc1ccc(Cl)c2CCCc12
Show InChI InChI=1S/C15H20ClNO/c1-17-9-3-4-11(17)10-18-15-8-7-14(16)12-5-2-6-13(12)15/h7-8,11H,2-6,9-10H2,1H3/t11-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
AffyNet 
Article
1.87E+3n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]-Cytisine as radioligand in whole rat brain


Bioorg Med Chem Lett 6: 2283-2288 (1996)

More data for this
Ligand-Target Pair
Nicotinic acetylcholine receptor alpha9/alpha10


(Rattus norvegicus)
BDBM50287817
PNG
((S)-1-Methyl-2-(2-trifluoromethyl-phenoxymethyl)-p...)
Show SMILES CN1CCC[C@H]1COc1ccccc1C(F)(F)F
Show InChI InChI=1S/C13H16F3NO/c1-17-8-4-5-10(17)9-18-12-7-3-2-6-11(12)13(14,15)16/h2-3,6-7,10H,4-5,8-9H2,1H3/t10-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
2.43E+3n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]-Cytisine as radioligand in whole rat brain


Bioorg Med Chem Lett 6: 2283-2288 (1996)

More data for this
Ligand-Target Pair
Nicotinic acetylcholine receptor alpha9/alpha10


(Rattus norvegicus)
BDBM50287831
PNG
((S)-2-(Naphthalen-1-yloxymethyl)-pyrrolidine | CHE...)
Show SMILES C(Oc1cccc2ccccc12)[C@@H]1CCCN1
Show InChI InChI=1S/C15H17NO/c1-2-8-14-12(5-1)6-3-9-15(14)17-11-13-7-4-10-16-13/h1-3,5-6,8-9,13,16H,4,7,10-11H2/t13-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
2.89E+3n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]-Cytisine as radioligand in whole rat brain


Bioorg Med Chem Lett 6: 2283-2288 (1996)

More data for this
Ligand-Target Pair
Nicotinic acetylcholine receptor alpha9/alpha10


(Rattus norvegicus)
BDBM50287847
PNG
((S)-2-Pentafluorophenyloxymethyl-pyrrolidine | CHE...)
Show SMILES Fc1c(F)c(F)c(OC[C@@H]2CCCN2)c(F)c1F
Show InChI InChI=1S/C11H10F5NO/c12-6-7(13)9(15)11(10(16)8(6)14)18-4-5-2-1-3-17-5/h5,17H,1-4H2/t5-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
3.07E+3n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]-Cytisine as radioligand in whole rat brain


Bioorg Med Chem Lett 6: 2283-2288 (1996)

More data for this
Ligand-Target Pair
Nicotinic acetylcholine receptor alpha9/alpha10


(Rattus norvegicus)
BDBM50287815
PNG
(1-[2-((S)-1-Methyl-pyrrolidin-2-ylmethoxy)-phenyl]...)
Show SMILES CN1CCC[C@H]1COc1ccccc1C(C)=O
Show InChI InChI=1S/C14H19NO2/c1-11(16)13-7-3-4-8-14(13)17-10-12-6-5-9-15(12)2/h3-4,7-8,12H,5-6,9-10H2,1-2H3/t12-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
AffyNet 
Article
3.33E+3n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]-Cytisine as radioligand in whole rat brain


Bioorg Med Chem Lett 6: 2283-2288 (1996)

More data for this
Ligand-Target Pair
Nicotinic acetylcholine receptor alpha9/alpha10


(Rattus norvegicus)
BDBM50287833
PNG
(7-((S)-1-Methyl-pyrrolidin-2-ylmethoxy)-quinoline ...)
Show SMILES CN1CCC[C@H]1COc1ccc2cccnc2c1
Show InChI InChI=1S/C15H18N2O/c1-17-9-3-5-13(17)11-18-14-7-6-12-4-2-8-16-15(12)10-14/h2,4,6-8,10,13H,3,5,9,11H2,1H3/t13-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
AffyNet 
Article
5.00E+3n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]-Cytisine as radioligand in whole rat brain


Bioorg Med Chem Lett 6: 2283-2288 (1996)

More data for this
Ligand-Target Pair
Nicotinic acetylcholine receptor alpha9/alpha10


(Rattus norvegicus)
BDBM50287822
PNG
(CHEMBL309428 | Phenyl-(S)-1-pyrrolidin-2-ylmethyl-...)
Show SMILES C(Nc1ccccc1)[C@@H]1CCCN1
Show InChI InChI=1S/C11H16N2/c1-2-5-10(6-3-1)13-9-11-7-4-8-12-11/h1-3,5-6,11-13H,4,7-9H2/t11-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents

AffyNet 
Article
5.09E+3n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]-Cytisine as radioligand in whole rat brain


Bioorg Med Chem Lett 6: 2283-2288 (1996)

More data for this
Ligand-Target Pair
Nicotinic acetylcholine receptor alpha9/alpha10


(Rattus norvegicus)
BDBM50287841
PNG
((S)-1-Ethyl-2-phenoxymethyl-pyrrolidine | CHEMBL30...)
Show SMILES CCN1CCC[C@H]1COc1ccccc1
Show InChI InChI=1S/C13H19NO/c1-2-14-10-6-7-12(14)11-15-13-8-4-3-5-9-13/h3-5,8-9,12H,2,6-7,10-11H2,1H3/t12-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
5.17E+3n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]-Cytisine as radioligand in whole rat brain


Bioorg Med Chem Lett 6: 2283-2288 (1996)

More data for this
Ligand-Target Pair
Nicotinic acetylcholine receptor alpha9/alpha10


(Rattus norvegicus)
BDBM50287836
PNG
((S)-2-(3-Fluoro-phenylsulfanylmethyl)-pyrrolidine ...)
Show SMILES Fc1cccc(SC[C@@H]2CCCN2)c1
Show InChI InChI=1S/C11H14FNS/c12-9-3-1-5-11(7-9)14-8-10-4-2-6-13-10/h1,3,5,7,10,13H,2,4,6,8H2/t10-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
5.41E+3n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]-Cytisine as radioligand in whole rat brain


Bioorg Med Chem Lett 6: 2283-2288 (1996)

More data for this
Ligand-Target Pair
Nicotinic acetylcholine receptor alpha9/alpha10


(Rattus norvegicus)
BDBM50287823
PNG
((S)-2-(Naphthalen-2-yloxymethyl)-pyrrolidine | CHE...)
Show SMILES C(Oc1ccc2ccccc2c1)[C@@H]1CCCN1
Show InChI InChI=1S/C15H17NO/c1-2-5-13-10-15(8-7-12(13)4-1)17-11-14-6-3-9-16-14/h1-2,4-5,7-8,10,14,16H,3,6,9,11H2/t14-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
6.89E+3n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]-Cytisine as radioligand in whole rat brain


Bioorg Med Chem Lett 6: 2283-2288 (1996)

More data for this
Ligand-Target Pair
Nicotinic acetylcholine receptor alpha9/alpha10


(Rattus norvegicus)
BDBM50287839
PNG
((S)-2-(2-Trifluoromethyl-phenoxymethyl)-pyrrolidin...)
Show SMILES FC(F)(F)c1ccccc1OC[C@@H]1CCCN1
Show InChI InChI=1S/C12H14F3NO/c13-12(14,15)10-5-1-2-6-11(10)17-8-9-4-3-7-16-9/h1-2,5-6,9,16H,3-4,7-8H2/t9-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
>1.00E+4n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]-Cytisine as radioligand in whole rat brain


Bioorg Med Chem Lett 6: 2283-2288 (1996)

More data for this
Ligand-Target Pair
Nicotinic acetylcholine receptor alpha9/alpha10


(Rattus norvegicus)
BDBM50287856
PNG
((S)-1-Methyl-2-pentafluorophenyloxymethyl-pyrrolid...)
Show SMILES CN1CCC[C@H]1COc1c(F)c(F)c(F)c(F)c1F
Show InChI InChI=1S/C12H12F5NO/c1-18-4-2-3-6(18)5-19-12-10(16)8(14)7(13)9(15)11(12)17/h6H,2-5H2,1H3/t6-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
>1.00E+4n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]-Cytisine as radioligand in whole rat brain


Bioorg Med Chem Lett 6: 2283-2288 (1996)

More data for this
Ligand-Target Pair
Nicotinic acetylcholine receptor alpha9/alpha10


(Rattus norvegicus)
BDBM50081496
PNG
(5-((S)-1-Azetidin-2-ylmethoxy)-pyrimidine | CHEMBL...)
Show SMILES C(Oc1cncnc1)[C@@H]1CCN1
Show InChI InChI=1S/C8H11N3O/c1-2-11-7(1)5-12-8-3-9-6-10-4-8/h3-4,6-7,11H,1-2,5H2/t7-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Nicotinic acetylcholine receptor binding activity was determined by ability of the compound to displace [125I]-alpha-BgT binding to rat brain membran...


Bioorg Med Chem Lett 9: 2747-52 (1999)

More data for this
Ligand-Target Pair
Nicotinic acetylcholine receptor alpha9/alpha10


(Rattus norvegicus)
BDBM50081484
PNG
(3-((S)-1-Methyl-pyrrolidin-3-yloxy)-pyridine | CHE...)
Show SMILES CN1CC[C@@H](C1)Oc1cccnc1
Show InChI InChI=1S/C10H14N2O/c1-12-6-4-10(8-12)13-9-3-2-5-11-7-9/h2-3,5,7,10H,4,6,8H2,1H3/t10-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Nicotinic acetylcholine receptor binding activity was determined by ability of the compound to displace [125I]-alpha-BgT binding to rat brain membran...


Bioorg Med Chem Lett 9: 2747-52 (1999)

More data for this
Ligand-Target Pair
Nicotinic acetylcholine receptor alpha9/alpha10


(Rattus norvegicus)
BDBM50081483
PNG
(3-((R)-1-Methyl-pyrrolidin-3-yloxy)-pyridine | CHE...)
Show SMILES CN1CC[C@H](C1)Oc1cccnc1
Show InChI InChI=1S/C10H14N2O/c1-12-6-4-10(8-12)13-9-3-2-5-11-7-9/h2-3,5,7,10H,4,6,8H2,1H3/t10-/m1/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Nicotinic acetylcholine receptor binding activity was determined by ability of the compound to displace [125I]-alpha-BgT binding to rat brain membran...


Bioorg Med Chem Lett 9: 2747-52 (1999)

More data for this
Ligand-Target Pair
Displayed 1 to 50 (of 54 total )  |  Next  |  Last  >>
Jump to: