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Compile Data Set for Download or QSAR

Found 59 hits Enz. Inhib. hit(s) with Target = 'Ornithine decarboxylase' AND taxid = 10116   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Ornithine decarboxylase


(Rattus norvegicus)
BDBM50028199
PNG
(2,5-Diamino-2-fluoromethyl-pent-3-enoic acid | CHE...)
Show SMILES NC\C=C\C(N)(CF)C(O)=O
Show InChI InChI=1S/C6H11FN2O2/c7-4-6(9,5(10)11)2-1-3-8/h1-2H,3-4,8-9H2,(H,10,11)/b2-1+
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2.70E+3n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
The apparent dissociation constant for irreversible inhibition of rat liver ornithine decarboxylase (ODC)


J Med Chem 26: 1551-6 (1983)

More data for this
Ligand-Target Pair
Ornithine decarboxylase


(Rattus norvegicus)
BDBM50020273
PNG
(2,5-Diamino-2-fluoromethyl-pentanoic acid | CHEMBL...)
Show SMILES NCCCC(N)(CF)C(O)=O
Show InChI InChI=1S/C6H13FN2O2/c7-4-6(9,5(10)11)2-1-3-8/h1-4,8-9H2,(H,10,11)
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2.70E+3n/an/an/an/an/an/an/an/a



Merrell Dow Research Institute

Curated by ChEMBL


Assay Description
In vitro inhibition against ornithine decarboxylase


J Med Chem 32: 170-3 (1989)

More data for this
Ligand-Target Pair
Ornithine decarboxylase


(Rattus norvegicus)
BDBM50028200
PNG
(2,5-Diamino-2-methyl-pent-3-enoic acid | CHEMBL400...)
Show SMILES CC(N)(\C=C\CN)C(O)=O
Show InChI InChI=1S/C6H12N2O2/c1-6(8,5(9)10)3-2-4-7/h2-3H,4,7-8H2,1H3,(H,9,10)/b3-2+
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2.70E+3n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
The apparent dissociation constant for irreversible inhibition of rat liver ornithine decarboxylase (ODC)


J Med Chem 26: 1551-6 (1983)

More data for this
Ligand-Target Pair
Ornithine decarboxylase


(Rattus norvegicus)
BDBM50020275
PNG
(CHEMBL413056 | Hept-6-yne-2,5-diamine)
Show SMILES C[C@H](N)CC[C@H](N)C#C
Show InChI InChI=1S/C7H14N2/c1-3-7(9)5-4-6(2)8/h1,6-7H,4-5,8-9H2,2H3/t6-,7+/m0/s1
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3.00E+3n/an/an/an/an/an/an/an/a



Merrell Dow Research Institute

Curated by ChEMBL


Assay Description
In vitro inhibition against ornithine decarboxylase


J Med Chem 32: 170-3 (1989)

More data for this
Ligand-Target Pair
Ornithine decarboxylase


(Rattus norvegicus)
BDBM50009841
PNG
(CHEMBL3247544)
Show SMILES NC\C=C\C(N)C(O)=O
Show InChI InChI=1S/C5H10N2O2/c6-3-1-2-4(7)5(8)9/h1-2,4H,3,6-7H2,(H,8,9)/b2-1+
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4.40E+3n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of rat liver ornithine decarboxylase


J Med Chem 21: 50-5 (1978)

More data for this
Ligand-Target Pair
Ornithine decarboxylase


(Rattus norvegicus)
BDBM50020274
PNG
(2,2-Difluoro-hex-5-yne-1,4-diamonium; dichloride |...)
Show SMILES [NH3+]CC(F)(F)CC([NH3+])C#C
Show InChI InChI=1S/C6H10F2N2/c1-2-5(10)3-6(7,8)4-9/h1,5H,3-4,9-10H2/p+2
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1.00E+4n/an/an/an/an/an/an/an/a



Merrell Dow Research Institute

Curated by ChEMBL


Assay Description
In vitro inhibition against ornithine decarboxylase


J Med Chem 32: 170-3 (1989)

More data for this
Ligand-Target Pair
Ornithine decarboxylase


(Rattus norvegicus)
BDBM50009922
PNG
(CHEMBL3247533)
Show SMILES C[C@](N)(CCCN)C(O)=O
Show InChI InChI=1S/C6H14N2O2.ClH/c1-6(8,5(9)10)3-2-4-7;/h2-4,7-8H2,1H3,(H,9,10);1H/t6-;/m0./s1
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1.90E+4n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Competitive inhibition of rat liver ornithine decarboxylase using DL-[1-14C]ornithine as substrate after 1 hr by dixon plot analysis


J Med Chem 21: 50-5 (1978)

More data for this
Ligand-Target Pair
Ornithine decarboxylase


(Rattus norvegicus)
BDBM50009922
PNG
(CHEMBL3247533)
Show SMILES C[C@](N)(CCCN)C(O)=O
Show InChI InChI=1S/C6H14N2O2.ClH/c1-6(8,5(9)10)3-2-4-7;/h2-4,7-8H2,1H3,(H,9,10);1H/t6-;/m0./s1
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2.00E+4n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Competitive inhibition of ornithine decarboxylase in rat HTC cells using DL-[1-14C]ornithine as substrate after 1 hr by dixon plot analysis


J Med Chem 21: 50-5 (1978)

More data for this
Ligand-Target Pair
Ornithine decarboxylase


(Rattus norvegicus)
BDBM50028198
PNG
(2,5-Diamino-2-difluoromethyl-pent-3-enoic acid | C...)
Show SMILES NC\C=C\C(N)(C(F)F)C(O)=O
Show InChI InChI=1S/C6H10F2N2O2/c7-4(8)6(10,5(11)12)2-1-3-9/h1-2,4H,3,9-10H2,(H,11,12)/b2-1+
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3.00E+4n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
The apparent dissociation constant for irreversible inhibition of rat liver ornithine decarboxylase (ODC)


J Med Chem 26: 1551-6 (1983)

More data for this
Ligand-Target Pair
Ornithine decarboxylase


(Rattus norvegicus)
BDBM50028194
PNG
(5,5-Difluoro-pentane-1,4-diamine | CHEMBL39264)
Show SMILES NCCCC(N)C(F)F
Show InChI InChI=1S/C5H12F2N2/c6-5(7)4(9)2-1-3-8/h4-5H,1-3,8-9H2
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3.00E+4n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
The apparent dissociation constant for irreversible inhibition of rat liver ornithine decarboxylase (ODC)


J Med Chem 26: 1551-6 (1983)

More data for this
Ligand-Target Pair
Ornithine decarboxylase


(Rattus norvegicus)
BDBM50028197
PNG
(2-(difluoromethyl)ornithine | CHEMBL830 | EFLORNIT...)
Show SMILES NCCCC(N)(C(F)F)C(O)=O
Show InChI InChI=1S/C6H12F2N2O2/c7-4(8)6(10,5(11)12)2-1-3-9/h4H,1-3,9-10H2,(H,11,12)
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3.90E+4n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
The apparent dissociation constant for irreversible inhibition of rat liver ornithine decarboxylase (ODC)


J Med Chem 26: 1551-6 (1983)

More data for this
Ligand-Target Pair
Ornithine decarboxylase


(Rattus norvegicus)
BDBM50028201
PNG
(2,5-Diamino-2-methyl-pentanoic acid | CHEMBL36743)
Show SMILES CC(N)(CCCN)C(O)=O
Show InChI InChI=1S/C6H14N2O2/c1-6(8,5(9)10)3-2-4-7/h2-4,7-8H2,1H3,(H,9,10)
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4.00E+4n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Competitive inhibition of rat liver ornithine decarboxylase using DL-[1-14C]ornithine as substrate after 1 hr by dixon plot analysis


J Med Chem 21: 50-5 (1978)

More data for this
Ligand-Target Pair
Ornithine decarboxylase


(Rattus norvegicus)
BDBM50028201
PNG
(2,5-Diamino-2-methyl-pentanoic acid | CHEMBL36743)
Show SMILES CC(N)(CCCN)C(O)=O
Show InChI InChI=1S/C6H14N2O2/c1-6(8,5(9)10)3-2-4-7/h2-4,7-8H2,1H3,(H,9,10)
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4.00E+4n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
The apparent dissociation constant for irreversible inhibition of rat liver ornithine decarboxylase (ODC)


J Med Chem 26: 1551-6 (1983)

More data for this
Ligand-Target Pair
Ornithine decarboxylase


(Rattus norvegicus)
BDBM50028201
PNG
(2,5-Diamino-2-methyl-pentanoic acid | CHEMBL36743)
Show SMILES CC(N)(CCCN)C(O)=O
Show InChI InChI=1S/C6H14N2O2/c1-6(8,5(9)10)3-2-4-7/h2-4,7-8H2,1H3,(H,9,10)
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4.00E+4n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Competitive inhibition of ornithine decarboxylase in rat HTC cells using DL-[1-14C]ornithine as substrate after 1 hr by dixon plot analysis


J Med Chem 21: 50-5 (1978)

More data for this
Ligand-Target Pair
Ornithine decarboxylase


(Rattus norvegicus)
BDBM50028193
PNG
(5-Fluoro-pent-2-ene-1,4-diamine | CHEMBL288059)
Show SMILES NC\C=C\C(N)CF
Show InChI InChI=1S/C5H11FN2/c6-4-5(8)2-1-3-7/h1-2,5H,3-4,7-8H2/b2-1+
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4.20E+4n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
The apparent dissociation constant for irreversible inhibition of rat liver ornithine decarboxylase (ODC)


J Med Chem 26: 1551-6 (1983)

More data for this
Ligand-Target Pair
Ornithine decarboxylase


(Rattus norvegicus)
BDBM50028195
PNG
(5-Fluoro-pentane-1,4-diamine | CHEMBL290500)
Show SMILES NCCCC(N)CF
Show InChI InChI=1S/C5H13FN2/c6-4-5(8)2-1-3-7/h5H,1-4,7-8H2
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5.60E+4n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
The apparent dissociation constant for irreversible inhibition of rat liver ornithine decarboxylase (ODC)


J Med Chem 26: 1551-6 (1983)

More data for this
Ligand-Target Pair
Ornithine decarboxylase


(Rattus norvegicus)
BDBM50028196
PNG
(5,5-Difluoro-pent-2-ene-1,4-diamine | CHEMBL41597)
Show SMILES NC\C=C\C(N)C(F)F
Show InChI InChI=1S/C5H10F2N2/c6-5(7)4(9)2-1-3-8/h1-2,4-5H,3,8-9H2/b2-1+
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6.00E+4n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
The apparent dissociation constant for irreversible inhibition of rat liver ornithine decarboxylase (ODC)


J Med Chem 26: 1551-6 (1983)

More data for this
Ligand-Target Pair
Ornithine decarboxylase


(Rattus norvegicus)
BDBM50009924
PNG
(CHEMBL3247542)
Show SMILES N[C@H]1CC[C@@](N)(CC1)C(O)=O
Show InChI InChI=1S/C7H14N2O2/c8-5-1-3-7(9,4-2-5)6(10)11/h5H,1-4,8-9H2,(H,10,11)/t5-,7+
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7.00E+4n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Competitive inhibition of ornithine decarboxylase in rat HTC cells using DL-[1-14C]ornithine as substrate after 1 hr by dixon plot analysis


J Med Chem 21: 50-5 (1978)

More data for this
Ligand-Target Pair
Ornithine decarboxylase


(Rattus norvegicus)
BDBM50009924
PNG
(CHEMBL3247542)
Show SMILES N[C@H]1CC[C@@](N)(CC1)C(O)=O
Show InChI InChI=1S/C7H14N2O2/c8-5-1-3-7(9,4-2-5)6(10)11/h5H,1-4,8-9H2,(H,10,11)/t5-,7+
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7.00E+4n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Competitive inhibition of rat liver ornithine decarboxylase using DL-[1-14C]ornithine as substrate after 1 hr by dixon plot analysis


J Med Chem 21: 50-5 (1978)

More data for this
Ligand-Target Pair
Ornithine decarboxylase


(Rattus norvegicus)
BDBM50020273
PNG
(2,5-Diamino-2-fluoromethyl-pentanoic acid | CHEMBL...)
Show SMILES NCCCC(N)(CF)C(O)=O
Show InChI InChI=1S/C6H13FN2O2/c7-4-6(9,5(10)11)2-1-3-8/h1-4,8-9H2,(H,10,11)
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7.50E+4n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
The apparent dissociation constant for irreversible inhibition of rat liver ornithine decarboxylase (ODC)


J Med Chem 26: 1551-6 (1983)

More data for this
Ligand-Target Pair
Ornithine decarboxylase


(Rattus norvegicus)
BDBM50009740
PNG
(CHEMBL3247539)
Show SMILES Cl.NCCCC(N)c1nnn[nH]1
Show InChI InChI=1S/C5H12N6.ClH/c6-3-1-2-4(7)5-8-10-11-9-5;/h4H,1-3,6-7H2,(H,8,9,10,11);1H
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1.20E+5n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Competitive inhibition of rat liver ornithine decarboxylase using DL-[1-14C]ornithine as substrate after 1 hr by dixon plot analysis


J Med Chem 21: 50-5 (1978)

More data for this
Ligand-Target Pair
Ornithine decarboxylase


(Rattus norvegicus)
BDBM50009740
PNG
(CHEMBL3247539)
Show SMILES Cl.NCCCC(N)c1nnn[nH]1
Show InChI InChI=1S/C5H12N6.ClH/c6-3-1-2-4(7)5-8-10-11-9-5;/h4H,1-3,6-7H2,(H,8,9,10,11);1H
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1.40E+5n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Competitive inhibition of ornithine decarboxylase in rat HTC cells using DL-[1-14C]ornithine as substrate after 1 hr by dixon plot analysis


J Med Chem 21: 50-5 (1978)

More data for this
Ligand-Target Pair
Ornithine decarboxylase


(Rattus norvegicus)
BDBM50009921
PNG
(CHEMBL3247530)
Show SMILES CNCCCC(C)(N)C(O)=O
Show InChI InChI=1S/C7H16N2O2/c1-7(8,6(10)11)4-3-5-9-2/h9H,3-5,8H2,1-2H3,(H,10,11)
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5.00E+5n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Competitive inhibition of rat liver ornithine decarboxylase using DL-[1-14C]ornithine as substrate after 1 hr by dixon plot analysis


J Med Chem 21: 50-5 (1978)

More data for this
Ligand-Target Pair
Ornithine decarboxylase


(Rattus norvegicus)
BDBM50029359
PNG
(4-Amino-2-aminomethyl-3-methyl-butyric acid | CHEM...)
Show SMILES CC(CN)C(CN)C(O)=O
Show InChI InChI=1S/C6H14N2O2/c1-4(2-7)5(3-8)6(9)10/h4-5H,2-3,7-8H2,1H3,(H,9,10)
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7.20E+5n/an/an/an/an/an/an/an/a



Universidad de Buenos Aires

Curated by ChEMBL


Assay Description
Inhibition of liver Ornithine decarboxylase in thioacetamide-treated rat


J Med Chem 38: 4337-41 (1995)

More data for this
Ligand-Target Pair
Ornithine decarboxylase


(Rattus norvegicus)
BDBM50009923
PNG
(CHEMBL3247534)
Show SMILES C[C@@](N)(CCCN)C(O)=O
Show InChI InChI=1S/C6H14N2O2.ClH/c1-6(8,5(9)10)3-2-4-7;/h2-4,7-8H2,1H3,(H,9,10);1H/t6-;/m1./s1
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1.05E+6n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Competitive inhibition of ornithine decarboxylase in rat HTC cells using DL-[1-14C]ornithine as substrate after 1 hr by dixon plot analysis


J Med Chem 21: 50-5 (1978)

More data for this
Ligand-Target Pair
Ornithine decarboxylase


(Rattus norvegicus)
BDBM50009923
PNG
(CHEMBL3247534)
Show SMILES C[C@@](N)(CCCN)C(O)=O
Show InChI InChI=1S/C6H14N2O2.ClH/c1-6(8,5(9)10)3-2-4-7;/h2-4,7-8H2,1H3,(H,9,10);1H/t6-;/m1./s1
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1.30E+6n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Competitive inhibition of rat liver ornithine decarboxylase using DL-[1-14C]ornithine as substrate after 1 hr by dixon plot analysis


J Med Chem 21: 50-5 (1978)

More data for this
Ligand-Target Pair
Ornithine decarboxylase


(Rattus norvegicus)
BDBM50029357
PNG
(4-Amino-2-aminomethyl-2,3-dimethyl-butyric acid | ...)
Show SMILES CC(CN)C(C)(CN)C(O)=O
Show InChI InChI=1S/C7H16N2O2/c1-5(3-8)7(2,4-9)6(10)11/h5H,3-4,8-9H2,1-2H3,(H,10,11)
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1.65E+6n/an/an/an/an/an/an/an/a



Universidad de Buenos Aires

Curated by ChEMBL


Assay Description
Inhibition of liver Ornithine decarboxylase in thioacetamide-treated rat


J Med Chem 38: 4337-41 (1995)

More data for this
Ligand-Target Pair
Ornithine decarboxylase


(Rattus norvegicus)
BDBM50029366
PNG
(4-Amino-2-aminomethyl-butyric acid | CHEMBL139503)
Show SMILES NCCC(CN)C(O)=O
Show InChI InChI=1S/C5H12N2O2/c6-2-1-4(3-7)5(8)9/h4H,1-3,6-7H2,(H,8,9)
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1.79E+6n/an/an/an/an/an/an/an/a



Universidad de Buenos Aires

Curated by ChEMBL


Assay Description
Inhibition of liver Ornithine decarboxylase in thioacetamide-treated rat


J Med Chem 38: 4337-41 (1995)

More data for this
Ligand-Target Pair
Ornithine decarboxylase


(Rattus norvegicus)
BDBM50009353
PNG
(1,5,10-triazadecane | 4-azaoctamethylenediamine | ...)
Show SMILES NCCCCNCCCN
Show InChI InChI=1S/C7H19N3/c8-4-1-2-6-10-7-3-5-9/h10H,1-9H2
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2.70E+6n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Competitive inhibition of Sprague-Dawley rat prostate ornithine decarboxylase using DL-[1-14C]ornithine as substrate by liquid scintillation counting...


J Med Chem 21: 50-5 (1978)

More data for this
Ligand-Target Pair
Ornithine decarboxylase


(Rattus norvegicus)
BDBM50015684
PNG
((racemic+meso) 2-Methyl-pentane-1,4-diamine | CHEM...)
Show SMILES CC(N)CC(C)CN
Show InChI InChI=1S/C6H16N2/c1-5(4-7)3-6(2)8/h5-6H,3-4,7-8H2,1-2H3
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2.90E+6n/an/an/an/an/an/an/an/a



Universidad de Buenos Aires

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against Ornithine Decarboxylase (ODC) isolated from the livers of thioactamide treated rats.


J Med Chem 33: 1969-74 (1990)

More data for this
Ligand-Target Pair
Ornithine decarboxylase


(Rattus norvegicus)
BDBM50015683
PNG
(CHEMBL59625 | N*1*,N*1*-Dimethyl-butane-1,4-diamin...)
Show SMILES CN(C)CCCCN
Show InChI InChI=1S/C6H16N2/c1-8(2)6-4-3-5-7/h3-7H2,1-2H3
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3.00E+6n/an/an/an/an/an/an/an/a



Universidad de Buenos Aires

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against Ornithine Decarboxylase (ODC) isolated from the livers of thioactamide treated rats.


J Med Chem 33: 1969-74 (1990)

More data for this
Ligand-Target Pair
Ornithine decarboxylase


(Rattus norvegicus)
BDBM50009385
PNG
(1,4-butylenediamine | 1,4-tetramethylenediamine | ...)
Show InChI InChI=1S/C4H12N2/c5-3-1-2-4-6/h1-6H2
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3.30E+6n/an/an/an/an/an/an/an/a



Universidad de Buenos Aires

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against Ornithine Decarboxylase (ODC) isolated from the livers of thioactamide treated rats.


J Med Chem 33: 1969-74 (1990)

More data for this
Ligand-Target Pair
Ornithine decarboxylase


(Rattus norvegicus)
BDBM50009385
PNG
(1,4-butylenediamine | 1,4-tetramethylenediamine | ...)
Show InChI InChI=1S/C4H12N2/c5-3-1-2-4-6/h1-6H2
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3.50E+6n/an/an/an/an/an/an/an/a



Universidad de Buenos Aires

Curated by ChEMBL


Assay Description
Inhibition of liver Ornithine decarboxylase in thioacetamide-treated rat


J Med Chem 38: 4337-41 (1995)

More data for this
Ligand-Target Pair
Ornithine decarboxylase


(Rattus norvegicus)
BDBM50015686
PNG
((racemic+meso) 3-Methyl-pentane-1,4-diamine | CHEM...)
Show SMILES CC(N)C(C)CCN
Show InChI InChI=1S/C6H16N2/c1-5(3-4-7)6(2)8/h5-6H,3-4,7-8H2,1-2H3
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3.80E+6n/an/an/an/an/an/an/an/a



Universidad de Buenos Aires

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against Ornithine Decarboxylase (ODC) isolated from the livers of thioactamide treated rats.


J Med Chem 33: 1969-74 (1990)

More data for this
Ligand-Target Pair
Ornithine decarboxylase


(Rattus norvegicus)
BDBM50029364
PNG
(2,3-dimethyl-1,4-butanediammonium)
Show SMILES CC(C[NH3+])C(C)C[NH3+]
Show InChI InChI=1S/C6H16N2/c1-5(3-7)6(2)4-8/h5-6H,3-4,7-8H2,1-2H3/p+2
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6.10E+6n/an/an/an/an/an/an/an/a



Universidad de Buenos Aires

Curated by ChEMBL


Assay Description
Inhibition of liver Ornithine decarboxylase in thioacetamide-treated rat


J Med Chem 38: 4337-41 (1995)

More data for this
Ligand-Target Pair
Ornithine decarboxylase


(Rattus norvegicus)
BDBM50029360
PNG
(2,2-dimethyl-1,4-butanediammonium)
Show SMILES CC(C)(C[NH3+])CC[NH3+]
Show InChI InChI=1S/C6H16N2/c1-6(2,5-8)3-4-7/h3-5,7-8H2,1-2H3/p+2
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>1.00E+7n/an/an/an/an/an/an/an/a



Universidad de Buenos Aires

Curated by ChEMBL


Assay Description
Inhibition of liver Ornithine decarboxylase in thioacetamide-treated rat


J Med Chem 38: 4337-41 (1995)

More data for this
Ligand-Target Pair
Ornithine decarboxylase


(Rattus norvegicus)
BDBM50029362
PNG
(2,2,3-trimethyl-1,4-butanediammonium)
Show SMILES CC(C[NH3+])C(C)(C)C[NH3+]
Show InChI InChI=1S/C7H18N2/c1-6(4-8)7(2,3)5-9/h6H,4-5,8-9H2,1-3H3/p+2
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>1.05E+7n/an/an/an/an/an/an/an/a



Universidad de Buenos Aires

Curated by ChEMBL


Assay Description
Inhibition of liver Ornithine decarboxylase in thioacetamide-treated rat


J Med Chem 38: 4337-41 (1995)

More data for this
Ligand-Target Pair
Ornithine decarboxylase


(Rattus norvegicus)
BDBM50029365
PNG
(4-Amino-2-aminomethyl-3,3-dimethyl-butyric acid | ...)
Show SMILES CC(C)(CN)C(CN)C(O)=O
Show InChI InChI=1S/C7H16N2O2/c1-7(2,4-9)5(3-8)6(10)11/h5H,3-4,8-9H2,1-2H3,(H,10,11)
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>1.10E+7n/an/an/an/an/an/an/an/a



Universidad de Buenos Aires

Curated by ChEMBL


Assay Description
Inhibition of liver Ornithine decarboxylase in thioacetamide-treated rat


J Med Chem 38: 4337-41 (1995)

More data for this
Ligand-Target Pair
Ornithine decarboxylase


(Rattus norvegicus)
BDBM50029361
PNG
(2,2,3,3-tetramethyl-1,4-butanediammonium)
Show SMILES CC(C)(C[NH3+])C(C)(C)C[NH3+]
Show InChI InChI=1S/C8H20N2/c1-7(2,5-9)8(3,4)6-10/h5-6,9-10H2,1-4H3/p+2
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>1.10E+7n/an/an/an/an/an/an/an/a



Universidad de Buenos Aires

Curated by ChEMBL


Assay Description
Inhibition of liver Ornithine decarboxylase in thioacetamide-treated rat


J Med Chem 38: 4337-41 (1995)

More data for this
Ligand-Target Pair
Ornithine decarboxylase


(Rattus norvegicus)
BDBM50029358
PNG
(4-Amino-2-aminomethyl-2-methyl-butyric acid | CHEM...)
Show SMILES CC(CN)(CCN)C(O)=O
Show InChI InChI=1S/C6H14N2O2/c1-6(4-8,2-3-7)5(9)10/h2-4,7-8H2,1H3,(H,9,10)
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>1.10E+7n/an/an/an/an/an/an/an/a



Universidad de Buenos Aires

Curated by ChEMBL


Assay Description
Inhibition of liver Ornithine decarboxylase in thioacetamide-treated rat


J Med Chem 38: 4337-41 (1995)

More data for this
Ligand-Target Pair
Ornithine decarboxylase


(Rattus norvegicus)
BDBM50029363
PNG
(4-Amino-2-aminomethyl-2,3,3-trimethyl-butyric acid...)
Show SMILES CC(C)(CN)C(C)(CN)C(O)=O
Show InChI InChI=1S/C8H18N2O2/c1-7(2,4-9)8(3,5-10)6(11)12/h4-5,9-10H2,1-3H3,(H,11,12)
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>1.10E+7n/an/an/an/an/an/an/an/a



Universidad de Buenos Aires

Curated by ChEMBL


Assay Description
Inhibition of liver Ornithine decarboxylase in thioacetamide-treated rat


J Med Chem 38: 4337-41 (1995)

More data for this
Ligand-Target Pair
Ornithine decarboxylase


(Rattus norvegicus)
BDBM50005726
PNG
(CHEMBL27061 | O-(3-Amino-2-fluoro-propyl)-hydroxyl...)
Show SMILES NCC(F)CON
Show InChI InChI=1S/C3H9FN2O/c4-3(1-5)2-7-6/h3H,1-2,5-6H2
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n/an/a 14n/an/an/an/an/an/a



Ciba-Geigy AG.

Curated by ChEMBL


Assay Description
Inhibitory activity against Rat liver ornithine decarboxylase(ODC)


J Med Chem 35: 1339-44 (1992)

More data for this
Ligand-Target Pair
Ornithine decarboxylase


(Rattus norvegicus)
BDBM50005712
PNG
((S)1-Amino-3-aminooxy-propan-2-ol | CHEMBL26435)
Show SMILES NC[C@H](O)CON
Show InChI InChI=1S/C3H10N2O2/c4-1-3(6)2-7-5/h3,6H,1-2,4-5H2/t3-/m0/s1
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n/an/a 33n/an/an/an/an/an/a



Ciba-Geigy AG.

Curated by ChEMBL


Assay Description
Inhibitory activity against Rat liver ornithine decarboxylase(ODC)


J Med Chem 35: 1339-44 (1992)

More data for this
Ligand-Target Pair
Ornithine decarboxylase


(Rattus norvegicus)
BDBM50005719
PNG
((APA)O-(3-Amino-propyl)-hydroxylamine | 3-AMINOOXY...)
Show InChI InChI=1S/C3H10N2O/c4-2-1-3-6-5/h1-5H2
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n/an/a 35n/an/an/an/an/an/a



University of Dundee

Curated by ChEMBL


Assay Description
Inhibition of rat liver ornithine decarboxylase


Citation and Details
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Ornithine decarboxylase


(Rattus norvegicus)
BDBM50005719
PNG
((APA)O-(3-Amino-propyl)-hydroxylamine | 3-AMINOOXY...)
Show InChI InChI=1S/C3H10N2O/c4-2-1-3-6-5/h1-5H2
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n/an/a 35n/an/an/an/an/an/a



Ciba-Geigy AG.

Curated by ChEMBL


Assay Description
Inhibitory activity against Rat liver ornithine decarboxylase(ODC)


J Med Chem 35: 1339-44 (1992)

More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Ornithine decarboxylase


(Rattus norvegicus)
BDBM50005727
PNG
(1-Amino-3-aminooxy-propan-2-ol | CHEMBL26857)
Show SMILES NCC(O)CON
Show InChI InChI=1S/C3H10N2O2/c4-1-3(6)2-7-5/h3,6H,1-2,4-5H2
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n/an/a 39n/an/an/an/an/an/a



University of Dundee

Curated by ChEMBL


Assay Description
Inhibition of rat liver ornithine decarboxylase


Citation and Details
More data for this
Ligand-Target Pair
Ornithine decarboxylase


(Rattus norvegicus)
BDBM50005727
PNG
(1-Amino-3-aminooxy-propan-2-ol | CHEMBL26857)
Show SMILES NCC(O)CON
Show InChI InChI=1S/C3H10N2O2/c4-1-3(6)2-7-5/h3,6H,1-2,4-5H2
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n/an/a 39n/an/an/an/an/an/a



Ciba-Geigy AG.

Curated by ChEMBL


Assay Description
Inhibitory activity against Rat liver ornithine decarboxylase(ODC)


J Med Chem 35: 1339-44 (1992)

More data for this
Ligand-Target Pair
Ornithine decarboxylase


(Rattus norvegicus)
BDBM50005725
PNG
((R)1-Amino-3-aminooxy-propan-2-ol | CHEMBL284573)
Show SMILES NC[C@@H](O)CON
Show InChI InChI=1S/C3H10N2O2/c4-1-3(6)2-7-5/h3,6H,1-2,4-5H2/t3-/m1/s1
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n/an/a 49n/an/an/an/an/an/a



Ciba-Geigy AG.

Curated by ChEMBL


Assay Description
Inhibitory activity against Rat liver ornithine decarboxylase(ODC)


J Med Chem 35: 1339-44 (1992)

More data for this
Ligand-Target Pair
Ornithine decarboxylase


(Rattus norvegicus)
BDBM50005714
PNG
(CHEMBL15650 | O-(3-Amino-2-chloro-propyl)-hydroxyl...)
Show SMILES NCC(Cl)CON
Show InChI InChI=1S/C3H9ClN2O/c4-3(1-5)2-7-6/h3H,1-2,5-6H2
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n/an/a 93n/an/an/an/an/an/a



Ciba-Geigy AG.

Curated by ChEMBL


Assay Description
Inhibitory activity against Rat liver ornithine decarboxylase(ODC)


J Med Chem 35: 1339-44 (1992)

More data for this
Ligand-Target Pair
Ornithine decarboxylase


(Rattus norvegicus)
BDBM50005713
PNG
(CHEMBL282411 | Methanesulfonic acid 1-aminomethyl-...)
Show SMILES CS(=O)(=O)OC(CN)CON
Show InChI InChI=1S/C4H12N2O4S/c1-11(7,8)10-4(2-5)3-9-6/h4H,2-3,5-6H2,1H3
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n/an/a 1.10E+3n/an/an/an/an/an/a



Ciba-Geigy AG.

Curated by ChEMBL


Assay Description
Inhibitory activity against Rat liver ornithine decarboxylase(ODC)


J Med Chem 35: 1339-44 (1992)

More data for this
Ligand-Target Pair
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