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Compile Data Set for Download or QSAR

Found 623 hits Enz. Inhib. hit(s) with Target = 'PTK2B protein tyrosine kinase 2 beta (PTK2B)' AND taxid = 9606   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM50341636
PNG
((3Z)-N-(3-CHLOROPHENYL)-3-({3,5-DIMETHYL-4-[(4-MET...)
Show SMILES CN(c1cccc(Cl)c1)S(=O)(=O)c1ccc2NC(=O)\C(=C/c3[nH]c(C)c(C(=O)N4CCN(C)CC4)c3C)c2c1
Show InChI InChI=1S/C28H30ClN5O4S/c1-17-25(30-18(2)26(17)28(36)34-12-10-32(3)11-13-34)16-23-22-15-21(8-9-24(22)31-27(23)35)39(37,38)33(4)20-7-5-6-19(29)14-20/h5-9,14-16,30H,10-13H2,1-4H3,(H,31,35)/b23-16-
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10.5n/an/an/an/an/an/an/an/a



Sandia National Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PYK2 by ESI-MS analysis


J Med Chem 55: 1926-39 (2012)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM4339
PNG
((3,4-Dihydroxybenzylidene)malononitrile | 2-[(3,4-...)
Show SMILES Oc1ccc(C=C(C#N)C#N)cc1O
Show InChI InChI=1S/C10H6N2O2/c11-5-8(6-12)3-7-1-2-9(13)10(14)4-7/h1-4,13-14H
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162n/an/an/an/an/an/an/an/a



Sandia National Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PYK2 by ESI-MS analysis


J Med Chem 55: 1926-39 (2012)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM50020310
PNG
(CHEMBL3288854)
Show SMILES CN1CCN(CCC(=O)Nc2c(C)[nH]c(\C=C3/C(=O)Nc4ccc(F)cc34)c2C)CC1
Show InChI InChI=1S/C23H28FN5O2/c1-14-20(13-18-17-12-16(24)4-5-19(17)26-23(18)31)25-15(2)22(14)27-21(30)6-7-29-10-8-28(3)9-11-29/h4-5,12-13,25H,6-11H2,1-3H3,(H,26,31)(H,27,30)/b18-13-
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340n/an/an/an/an/an/an/an/a



Qilu Pharmaceutical Co, Ltd

Curated by ChEMBL


Assay Description
Binding affinity to PYK2 (unknown origin)


Eur J Med Chem 82: 139-51 (2014)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM7364
PNG
(6-phenyl[5H]pyrrolo[2,3-b]pyrazine (aloisine) 38 |...)
Show SMILES CCCCc1c([nH]c2nccnc12)-c1ccc(OC)cc1
Show InChI InChI=1S/C17H19N3O/c1-3-4-5-14-15(12-6-8-13(21-2)9-7-12)20-17-16(14)18-10-11-19-17/h6-11H,3-5H2,1-2H3,(H,19,20)
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933n/an/an/an/an/an/an/an/a



Sandia National Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PYK2 by ESI-MS analysis


J Med Chem 55: 1926-39 (2012)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM92422
PNG
(CHEMBL407391 | PU09)
Show SMILES CN(C)c1ncnc2nc[nH]c12
Show InChI InChI=1S/C7H9N5/c1-12(2)7-5-6(9-3-8-5)10-4-11-7/h3-4H,1-2H3,(H,8,9,10,11)
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>1.00E+4n/an/an/an/an/an/an/an/a



Sandia National Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PYK2 by ESI-MS analysis


J Med Chem 55: 1926-39 (2012)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM7680
PNG
(4-[2-(5-Bromo-2-oxo-1,2-dihydro-3H-indol-3-ylidene...)
Show SMILES NS(=O)(=O)c1ccc(NN=C2C(=O)Nc3ccc(Br)cc23)cc1
Show InChI InChI=1S/C14H11BrN4O3S/c15-8-1-6-12-11(7-8)13(14(20)17-12)19-18-9-2-4-10(5-3-9)23(16,21)22/h1-7,18H,(H2,16,21,22)(H,17,19,20)
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>1.00E+4n/an/an/an/an/an/an/an/a



Sandia National Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PYK2 by ESI-MS analysis


J Med Chem 55: 1926-39 (2012)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM50383081
PNG
(SCYTONEMIN)
Show SMILES Oc1ccc(\C=C2/C3Nc4ccccc4C3=C(C2=O)C2=C3C(=Nc4ccccc34)\C(=C/c3ccc(O)cc3)C2=O)cc1
Show InChI InChI=1S/C36H22N2O4/c39-21-13-9-19(10-14-21)17-25-33-29(23-5-1-3-7-27(23)37-33)31(35(25)41)32-30-24-6-2-4-8-28(24)38-34(30)26(36(32)42)18-20-11-15-22(40)16-12-20/h1-18,33,37,39-40H/b25-17+,26-18+
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>1.00E+4n/an/an/an/an/an/an/an/a



Sandia National Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PYK2 by ESI-MS analysis


J Med Chem 55: 1926-39 (2012)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM5544
PNG
(4-{[6-(cyclohexylmethoxy)-9H-purin-2-yl]amino}benz...)
Show SMILES NS(=O)(=O)c1ccc(Nc2nc(OCC3CCCCC3)c3[nH]cnc3n2)cc1
Show InChI InChI=1S/C18H22N6O3S/c19-28(25,26)14-8-6-13(7-9-14)22-18-23-16-15(20-11-21-16)17(24-18)27-10-12-4-2-1-3-5-12/h6-9,11-12H,1-5,10H2,(H2,19,25,26)(H2,20,21,22,23,24)
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>1.00E+4n/an/an/an/an/an/an/an/a



Sandia National Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PYK2 by ESI-MS analysis


J Med Chem 55: 1926-39 (2012)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM50246378
PNG
(CHEMBL452341 | N-(2-{[2-(2,2-Dioxo-2,3-dihydro-1H-...)
Show SMILES CN(c1ccccc1CNc1nc(Nc2ccc3NS(=O)(=O)Cc3c2)ncc1C(F)(F)F)S(C)(=O)=O
Show InChI InChI=1S/C21H21F3N6O4S2/c1-30(35(2,31)32)18-6-4-3-5-13(18)10-25-19-16(21(22,23)24)11-26-20(28-19)27-15-7-8-17-14(9-15)12-36(33,34)29-17/h3-9,11,29H,10,12H2,1-2H3,(H2,25,26,27,28)
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n/an/a 2n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibition of GST-tagged pyk2 (unknown origin) assessed as inhibition of poly-Glu-Tyr phosphorylation


Bioorg Med Chem Lett 18: 6071-7 (2008)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM50246239
PNG
(CHEMBL487229 | N-methyl-N-(2-((2-(1-oxoisoindolin-...)
Show SMILES CN(c1ccccc1CNc1nc(Nc2ccc3C(=O)NCc3c2)ncc1C(F)(F)F)S(C)(=O)=O
Show InChI InChI=1S/C22H21F3N6O3S/c1-31(35(2,33)34)18-6-4-3-5-13(18)10-26-19-17(22(23,24)25)12-28-21(30-19)29-15-7-8-16-14(9-15)11-27-20(16)32/h3-9,12H,10-11H2,1-2H3,(H,27,32)(H2,26,28,29,30)
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n/an/a 5n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibition of GST-tagged pyk2 (unknown origin) assessed as inhibition of poly-Glu-Tyr phosphorylation


Bioorg Med Chem Lett 18: 6071-7 (2008)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM50246330
PNG
(1-{6-[4-((1R,2R)-2-Dimethylamino-cyclopentylamino)...)
Show SMILES CN(C)[C@@H]1CCC[C@H]1Nc1nc(Nc2ccc3C4CCC(N4C(C)=O)c3c2)ncc1C(F)(F)F
Show InChI InChI=1S/C24H29F3N6O/c1-13(34)33-19-9-10-20(33)16-11-14(7-8-15(16)19)29-23-28-12-17(24(25,26)27)22(31-23)30-18-5-4-6-21(18)32(2)3/h7-8,11-12,18-21H,4-6,9-10H2,1-3H3,(H2,28,29,30,31)/t18-,19?,20?,21-/m1/s1
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n/an/a 6n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibition of GST-tagged pyk2 (unknown origin) assessed as inhibition of poly-Glu-Tyr phosphorylation


Bioorg Med Chem Lett 18: 6071-7 (2008)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM50402996
PNG
(CHEMBL2207440)
Show SMILES Cc1ccc(cc1)-n1nc(cc1NC(=O)Nc1cc(n[nH]1)-c1ccc2ncccc2c1)C(C)(C)C
Show InChI InChI=1S/C27H27N7O/c1-17-7-10-20(11-8-17)34-25(16-23(33-34)27(2,3)4)30-26(35)29-24-15-22(31-32-24)19-9-12-21-18(14-19)6-5-13-28-21/h5-16H,1-4H3,(H3,29,30,31,32,35)
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n/an/a 6.40n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Inhibition of human recombinant C-terminal His-tagged PYK2 using ATP as substrate incubated for 1 hr prior to substrate addition


Bioorg Med Chem Lett 22: 7523-9 (2012)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM50418579
PNG
(CHEMBL2029181)
Show SMILES CCNS(=C)(=O)c1ccc(Nc2ncc(c(N[C@@H]3CCC[C@H]3N(C)C)n2)C(F)(F)F)cc1
Show InChI InChI=1S/C21H29F3N6OS/c1-5-26-32(4,31)15-11-9-14(10-12-15)27-20-25-13-16(21(22,23)24)19(29-20)28-17-7-6-8-18(17)30(2)3/h9-13,17-18H,4-8H2,1-3H3,(H,26,31)(H2,25,27,28,29)/t17-,18-,32?/m1/s1
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n/an/a 10n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Inhibition of PYK2 by PYK2-LI-COR cellular assay


Bioorg Med Chem Lett 19: 3253-8 (2009)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM50246060
PNG
(CHEMBL472212 | CHEMBL541649 | N-methyl-N-(2-((2-(2...)
Show SMILES CN(c1ccccc1CNc1nc(Nc2ccc3NC(=O)Cc3c2)ncc1C(F)(F)F)S(C)(=O)=O
Show InChI InChI=1S/C22H21F3N6O3S/c1-31(35(2,33)34)18-6-4-3-5-13(18)11-26-20-16(22(23,24)25)12-27-21(30-20)28-15-7-8-17-14(9-15)10-19(32)29-17/h3-9,12H,10-11H2,1-2H3,(H,29,32)(H2,26,27,28,30)
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n/an/a 11n/an/an/an/an/an/a



Amgen, Inc.

Curated by ChEMBL


Assay Description
Inhibition of PYK2


J Med Chem 53: 4332-53 (2010)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM50448785
PNG
(CHEMBL3128069)
Show SMILES C[C@@H](Oc1cc(cnc1N)-c1sc(nc1C)[C@](C)(O)CO)c1cc(F)ccc1-n1nccn1
Show InChI InChI=1S/C22H23FN6O3S/c1-12-19(33-21(28-12)22(3,31)11-30)14-8-18(20(24)25-10-14)32-13(2)16-9-15(23)4-5-17(16)29-26-6-7-27-29/h4-10,13,30-31H,11H2,1-3H3,(H2,24,25)/t13-,22-/m1/s1
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n/an/a 12n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Inhibition of PTK2B (unknown origin) using Km levels of ATP


J Med Chem 57: 1170-87 (2014)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM50402999
PNG
(CHEMBL2207441)
Show SMILES Cc1ccc(cc1)-n1nc(cc1NC(=O)Nc1cc(n[nH]1)-c1ccc2nccnc2c1)C(C)(C)C
Show InChI InChI=1S/C26H26N8O/c1-16-5-8-18(9-6-16)34-24(15-22(33-34)26(2,3)4)30-25(35)29-23-14-20(31-32-23)17-7-10-19-21(13-17)28-12-11-27-19/h5-15H,1-4H3,(H3,29,30,31,32,35)
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n/an/a 13n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Inhibition of human recombinant C-terminal His-tagged PYK2 using ATP as substrate incubated for 1 hr prior to substrate addition


Bioorg Med Chem Lett 22: 7523-9 (2012)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM50318884
PNG
(CHEMBL1084546 | CHEMBL2430359 | N-methyl-N-(3-((2-...)
Show SMILES CN(c1ncccc1CNc1nc(Nc2ccc3NC(=O)Cc3c2)ncc1C(F)(F)F)S(C)(=O)=O
Show InChI InChI=1S/C21H20F3N7O3S/c1-31(35(2,33)34)19-12(4-3-7-25-19)10-26-18-15(21(22,23)24)11-27-20(30-18)28-14-5-6-16-13(8-14)9-17(32)29-16/h3-8,11H,9-10H2,1-2H3,(H,29,32)(H2,26,27,28,30)
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n/an/a 14n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of Pyk2 (unknown origin)


Citation and Details
More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM50018830
PNG
(CHEMBL3286830)
Show SMILES C[C@H]1Oc2cc(cnc2N)-c2c(CN(C)C(=O)c3ccc(F)cc13)nn(C)c2C#N
Show InChI InChI=1S/C21H19FN6O2/c1-11-15-7-13(22)4-5-14(15)21(29)27(2)10-16-19(17(8-23)28(3)26-16)12-6-18(30-11)20(24)25-9-12/h4-7,9,11H,10H2,1-3H3,(H2,24,25)/t11-/m1/s1
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n/an/a 14n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Inhibition of PTK2B (unknown origin) by TR-FRET-based Z'-LYTE assay


J Med Chem 57: 4720-44 (2014)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM50318884
PNG
(CHEMBL1084546 | CHEMBL2430359 | N-methyl-N-(3-((2-...)
Show SMILES CN(c1ncccc1CNc1nc(Nc2ccc3NC(=O)Cc3c2)ncc1C(F)(F)F)S(C)(=O)=O
Show InChI InChI=1S/C21H20F3N7O3S/c1-31(35(2,33)34)19-12(4-3-7-25-19)10-26-18-15(21(22,23)24)11-27-20(30-18)28-14-5-6-16-13(8-14)9-17(32)29-16/h3-8,11H,9-10H2,1-2H3,(H,29,32)(H2,26,27,28,30)
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n/an/a 14n/an/an/an/an/an/a



Amgen, Inc.

Curated by ChEMBL


Assay Description
Inhibition of PYK2


J Med Chem 53: 4332-53 (2010)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM50246188
PNG
(5-(4-(2-(methylsulfonyl)benzylamino)-5-(trifluorom...)
Show SMILES CS(=O)(=O)c1ccccc1CNc1nc(Nc2ccc3NC(=O)Cc3c2)ncc1C(F)(F)F
Show InChI InChI=1S/C21H18F3N5O3S/c1-33(31,32)17-5-3-2-4-12(17)10-25-19-15(21(22,23)24)11-26-20(29-19)27-14-6-7-16-13(8-14)9-18(30)28-16/h2-8,11H,9-10H2,1H3,(H,28,30)(H2,25,26,27,29)
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n/an/a 15n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibition of GST-tagged pyk2 (unknown origin) assessed as inhibition of poly-Glu-Tyr phosphorylation


Bioorg Med Chem Lett 18: 6071-7 (2008)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM50418579
PNG
(CHEMBL2029181)
Show SMILES CCNS(=C)(=O)c1ccc(Nc2ncc(c(N[C@@H]3CCC[C@H]3N(C)C)n2)C(F)(F)F)cc1
Show InChI InChI=1S/C21H29F3N6OS/c1-5-26-32(4,31)15-11-9-14(10-12-15)27-20-25-13-16(21(22,23)24)19(29-20)28-17-7-6-8-18(17)30(2)3/h9-13,17-18H,4-8H2,1-3H3,(H,26,31)(H2,25,27,28,29)/t17-,18-,32?/m1/s1
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n/an/a 16n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Inhibition of PYK2 assessed as reduction in peptide substrate phosphoryltion by fluorimetric method


Bioorg Med Chem Lett 19: 3253-8 (2009)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM50246189
PNG
(5-(4-(2-(pyrrolidin-1-ylsulfonyl)benzylamino)-5-(t...)
Show SMILES FC(F)(F)c1cnc(Nc2ccc3NC(=O)Cc3c2)nc1NCc1ccccc1S(=O)(=O)N1CCCC1
Show InChI InChI=1S/C24H23F3N6O3S/c25-24(26,27)18-14-29-23(30-17-7-8-19-16(11-17)12-21(34)31-19)32-22(18)28-13-15-5-1-2-6-20(15)37(35,36)33-9-3-4-10-33/h1-2,5-8,11,14H,3-4,9-10,12-13H2,(H,31,34)(H2,28,29,30,32)
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n/an/a 17n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibition of GST-tagged pyk2 (unknown origin) assessed as inhibition of poly-Glu-Tyr phosphorylation


Bioorg Med Chem Lett 18: 6071-7 (2008)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM245634
PNG
(US9428508, 89)
Show SMILES COc1cc(ccc1Nc1nc2NCCc2c(Nc2ccccc2S(=O)(=O)NC(C)C)n1)N1CCC(C1)N(C)C
Show InChI InChI=1/C28H38N8O3S/c1-18(2)34-40(37,38)25-9-7-6-8-23(25)30-27-21-12-14-29-26(21)32-28(33-27)31-22-11-10-19(16-24(22)39-5)36-15-13-20(17-36)35(3)4/h6-11,16,18,20,34H,12-15,17H2,1-5H3,(H3,29,30,31,32,33)
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n/an/a<20n/an/an/an/an/an/a



Centaurus BioPharma Co., Ltd.

US Patent


Assay Description
To measure inhibitory activity of FAK/PYK2 inhibitors, compounds were first prepare as a 1 mM stock in 100% DMSO and 3-fold serial dilution was perfo...


US Patent US9428508 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM245635
PNG
(US9428508, 90)
Show SMILES COc1cc(ccc1Nc1nc2NCCc2c(Nc2ccccc2S(=O)(=O)NC(C)C)n1)-n1cc(C)nc1C
Show InChI InChI=1S/C27H32N8O3S/c1-16(2)34-39(36,37)24-9-7-6-8-22(24)30-26-20-12-13-28-25(20)32-27(33-26)31-21-11-10-19(14-23(21)38-5)35-15-17(3)29-18(35)4/h6-11,14-16,34H,12-13H2,1-5H3,(H3,28,30,31,32,33)
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Centaurus BioPharma Co., Ltd.

US Patent


Assay Description
To measure inhibitory activity of FAK/PYK2 inhibitors, compounds were first prepare as a 1 mM stock in 100% DMSO and 3-fold serial dilution was perfo...


US Patent US9428508 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM245637
PNG
(US9428508, 92)
Show SMILES COc1cc(ccc1Nc1nc2NCCc2c(Nc2ccccc2S(=O)(=O)NC(C)C)n1)N1CCC(CC1)N1CCCCC1
Show InChI InChI=1S/C32H44N8O3S/c1-22(2)38-44(41,42)29-10-6-5-9-27(29)34-31-25-13-16-33-30(25)36-32(37-31)35-26-12-11-24(21-28(26)43-3)40-19-14-23(15-20-40)39-17-7-4-8-18-39/h5-6,9-12,21-23,38H,4,7-8,13-20H2,1-3H3,(H3,33,34,35,36,37)
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Centaurus BioPharma Co., Ltd.

US Patent


Assay Description
To measure inhibitory activity of FAK/PYK2 inhibitors, compounds were first prepare as a 1 mM stock in 100% DMSO and 3-fold serial dilution was perfo...


US Patent US9428508 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM245551
PNG
(US9428508, 5)
Show SMILES CCCNS(=O)(=O)c1ccccc1Nc1nc(Nc2ccc(cc2OC)N2CCOCC2)nc2NCCc12
Show InChI InChI=1S/C26H33N7O4S/c1-3-11-28-38(34,35)23-7-5-4-6-21(23)29-25-19-10-12-27-24(19)31-26(32-25)30-20-9-8-18(17-22(20)36-2)33-13-15-37-16-14-33/h4-9,17,28H,3,10-16H2,1-2H3,(H3,27,29,30,31,32)
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Centaurus BioPharma Co., Ltd.

US Patent


Assay Description
To measure inhibitory activity of FAK/PYK2 inhibitors, compounds were first prepare as a 1 mM stock in 100% DMSO and 3-fold serial dilution was perfo...


US Patent US9428508 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM245552
PNG
(US9428508, 6)
Show SMILES COc1cc(ccc1Nc1nc2NCCc2c(Nc2ccccc2S(=O)(=O)NC2CCC2)n1)N1CCOCC1
Show InChI InChI=1S/C27H33N7O4S/c1-37-23-17-19(34-13-15-38-16-14-34)9-10-21(23)30-27-31-25-20(11-12-28-25)26(32-27)29-22-7-2-3-8-24(22)39(35,36)33-18-5-4-6-18/h2-3,7-10,17-18,33H,4-6,11-16H2,1H3,(H3,28,29,30,31,32)
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Centaurus BioPharma Co., Ltd.

US Patent


Assay Description
To measure inhibitory activity of FAK/PYK2 inhibitors, compounds were first prepare as a 1 mM stock in 100% DMSO and 3-fold serial dilution was perfo...


US Patent US9428508 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM245570
PNG
(US9428508, 25)
Show SMILES CNS(=O)(=O)c1ccccc1Nc1nc(Nc2ccc(cc2OC)N2CCOCC2)nc2NCC(C)c12
Show InChI InChI=1/C25H31N7O4S/c1-16-15-27-23-22(16)24(28-19-6-4-5-7-21(19)37(33,34)26-2)31-25(30-23)29-18-9-8-17(14-20(18)35-3)32-10-12-36-13-11-32/h4-9,14,16,26H,10-13,15H2,1-3H3,(H3,27,28,29,30,31)
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Centaurus BioPharma Co., Ltd.

US Patent


Assay Description
To measure inhibitory activity of FAK/PYK2 inhibitors, compounds were first prepare as a 1 mM stock in 100% DMSO and 3-fold serial dilution was perfo...


US Patent US9428508 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM245571
PNG
(US9428508, 26)
Show SMILES CCCNS(=O)(=O)c1ccccc1Nc1nc(Nc2ccc(cc2OC)N2CCOCC2)nc2NCC(C)c12
Show InChI InChI=1/C27H35N7O4S/c1-4-11-29-39(35,36)23-8-6-5-7-21(23)30-26-24-18(2)17-28-25(24)32-27(33-26)31-20-10-9-19(16-22(20)37-3)34-12-14-38-15-13-34/h5-10,16,18,29H,4,11-15,17H2,1-3H3,(H3,28,30,31,32,33)
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Centaurus BioPharma Co., Ltd.

US Patent


Assay Description
To measure inhibitory activity of FAK/PYK2 inhibitors, compounds were first prepare as a 1 mM stock in 100% DMSO and 3-fold serial dilution was perfo...


US Patent US9428508 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM245572
PNG
(US9428508, 27)
Show SMILES COc1cc(ccc1Nc1nc2NCC(C)c2c(Nc2ccccc2S(=O)(=O)NC2CCC2)n1)N1CCOCC1
Show InChI InChI=1/C28H35N7O4S/c1-18-17-29-26-25(18)27(30-22-8-3-4-9-24(22)40(36,37)34-19-6-5-7-19)33-28(32-26)31-21-11-10-20(16-23(21)38-2)35-12-14-39-15-13-35/h3-4,8-11,16,18-19,34H,5-7,12-15,17H2,1-2H3,(H3,29,30,31,32,33)
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Centaurus BioPharma Co., Ltd.

US Patent


Assay Description
To measure inhibitory activity of FAK/PYK2 inhibitors, compounds were first prepare as a 1 mM stock in 100% DMSO and 3-fold serial dilution was perfo...


US Patent US9428508 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM245702
PNG
(US9428508, 157)
Show SMILES CNS(=O)(=O)c1ccccc1Nc1nc(Nc2cc(OC)c(OC)c(OC)c2)nc2NCC3(CC3)c12
Show InChI InChI=1S/C24H28N6O5S/c1-25-36(31,32)18-8-6-5-7-15(18)28-22-19-21(26-13-24(19)9-10-24)29-23(30-22)27-14-11-16(33-2)20(35-4)17(12-14)34-3/h5-8,11-12,25H,9-10,13H2,1-4H3,(H3,26,27,28,29,30)
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Centaurus BioPharma Co., Ltd.

US Patent


Assay Description
To measure inhibitory activity of FAK/PYK2 inhibitors, compounds were first prepare as a 1 mM stock in 100% DMSO and 3-fold serial dilution was perfo...


US Patent US9428508 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM245638
PNG
(US9428508, 93)
Show SMILES COc1cc(ccc1Nc1nc2NCCc2c(Nc2ccccc2S(=O)(=O)NC(C)C)n1)N1CCC(CC1)N1CCCC1
Show InChI InChI=1S/C31H42N8O3S/c1-21(2)37-43(40,41)28-9-5-4-8-26(28)33-30-24-12-15-32-29(24)35-31(36-30)34-25-11-10-23(20-27(25)42-3)39-18-13-22(14-19-39)38-16-6-7-17-38/h4-5,8-11,20-22,37H,6-7,12-19H2,1-3H3,(H3,32,33,34,35,36)
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Centaurus BioPharma Co., Ltd.

US Patent


Assay Description
To measure inhibitory activity of FAK/PYK2 inhibitors, compounds were first prepare as a 1 mM stock in 100% DMSO and 3-fold serial dilution was perfo...


US Patent US9428508 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM245640
PNG
(US9428508, 95)
Show SMILES COc1cc(ccc1Nc1nc2NCCc2c(Nc2ccccc2S(=O)(=O)NC(C)C)n1)N1CCC(CC1)N1CCOCC1
Show InChI InChI=1S/C31H42N8O4S/c1-21(2)37-44(40,41)28-7-5-4-6-26(28)33-30-24-10-13-32-29(24)35-31(36-30)34-25-9-8-23(20-27(25)42-3)38-14-11-22(12-15-38)39-16-18-43-19-17-39/h4-9,20-22,37H,10-19H2,1-3H3,(H3,32,33,34,35,36)
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Centaurus BioPharma Co., Ltd.

US Patent


Assay Description
To measure inhibitory activity of FAK/PYK2 inhibitors, compounds were first prepare as a 1 mM stock in 100% DMSO and 3-fold serial dilution was perfo...


US Patent US9428508 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM245641
PNG
(US9428508, 96)
Show SMILES COc1cc(ccc1Nc1nc2NCCc2c(Nc2ccccc2S(=O)(=O)NC(C)C)n1)N1CCC(CC1)N1CCN(C)CC1
Show InChI InChI=1S/C32H45N9O3S/c1-22(2)38-45(42,43)29-8-6-5-7-27(29)34-31-25-11-14-33-30(25)36-32(37-31)35-26-10-9-24(21-28(26)44-4)40-15-12-23(13-16-40)41-19-17-39(3)18-20-41/h5-10,21-23,38H,11-20H2,1-4H3,(H3,33,34,35,36,37)
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Centaurus BioPharma Co., Ltd.

US Patent


Assay Description
To measure inhibitory activity of FAK/PYK2 inhibitors, compounds were first prepare as a 1 mM stock in 100% DMSO and 3-fold serial dilution was perfo...


US Patent US9428508 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM245643
PNG
(US9428508, 98)
Show SMILES COc1cc(ccc1Nc1nc2NCCc2c(Nc2ccccc2S(=O)(=O)NC(C)C)n1)N1CCCCC1=O
Show InChI InChI=1S/C27H33N7O4S/c1-17(2)33-39(36,37)23-9-5-4-8-21(23)29-26-19-13-14-28-25(19)31-27(32-26)30-20-12-11-18(16-22(20)38-3)34-15-7-6-10-24(34)35/h4-5,8-9,11-12,16-17,33H,6-7,10,13-15H2,1-3H3,(H3,28,29,30,31,32)
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Centaurus BioPharma Co., Ltd.

US Patent


Assay Description
To measure inhibitory activity of FAK/PYK2 inhibitors, compounds were first prepare as a 1 mM stock in 100% DMSO and 3-fold serial dilution was perfo...


US Patent US9428508 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM245646
PNG
(US9428508, 101)
Show SMILES COc1cc(ccc1Nc1nc2NCC(C)c2c(Nc2ccccc2S(=O)(=O)NC(C)C)n1)N1CCOCC1
Show InChI InChI=1/C27H35N7O4S/c1-17(2)33-39(35,36)23-8-6-5-7-21(23)29-26-24-18(3)16-28-25(24)31-27(32-26)30-20-10-9-19(15-22(20)37-4)34-11-13-38-14-12-34/h5-10,15,17-18,33H,11-14,16H2,1-4H3,(H3,28,29,30,31,32)
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Centaurus BioPharma Co., Ltd.

US Patent


Assay Description
To measure inhibitory activity of FAK/PYK2 inhibitors, compounds were first prepare as a 1 mM stock in 100% DMSO and 3-fold serial dilution was perfo...


US Patent US9428508 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM245648
PNG
(US9428508, 103)
Show SMILES CNS(=O)(=O)c1ccccc1Nc1nc(Nc2ccc(cc2OC)N2CCOCC2)nc2NCC(C)(C)c12
Show InChI InChI=1S/C26H33N7O4S/c1-26(2)16-28-23-22(26)24(29-19-7-5-6-8-21(19)38(34,35)27-3)32-25(31-23)30-18-10-9-17(15-20(18)36-4)33-11-13-37-14-12-33/h5-10,15,27H,11-14,16H2,1-4H3,(H3,28,29,30,31,32)
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Centaurus BioPharma Co., Ltd.

US Patent


Assay Description
To measure inhibitory activity of FAK/PYK2 inhibitors, compounds were first prepare as a 1 mM stock in 100% DMSO and 3-fold serial dilution was perfo...


US Patent US9428508 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM245649
PNG
(US9428508, 104)
Show SMILES COc1cc(ccc1Nc1nc2NCC(C)(C)c2c(Nc2ccccc2S(=O)(=O)NC2CCC2)n1)N1CCOCC1
Show InChI InChI=1S/C29H37N7O4S/c1-29(2)18-30-26-25(29)27(31-22-9-4-5-10-24(22)41(37,38)35-19-7-6-8-19)34-28(33-26)32-21-12-11-20(17-23(21)39-3)36-13-15-40-16-14-36/h4-5,9-12,17,19,35H,6-8,13-16,18H2,1-3H3,(H3,30,31,32,33,34)
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Centaurus BioPharma Co., Ltd.

US Patent


Assay Description
To measure inhibitory activity of FAK/PYK2 inhibitors, compounds were first prepare as a 1 mM stock in 100% DMSO and 3-fold serial dilution was perfo...


US Patent US9428508 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM245650
PNG
(US9428508, 105)
Show SMILES COc1cc(ccc1Nc1nc2NCC(C)(C)c2c(Nc2ccccc2S(=O)(=O)NC(C)C)n1)N1CCOCC1
Show InChI InChI=1S/C28H37N7O4S/c1-18(2)34-40(36,37)23-9-7-6-8-21(23)30-26-24-25(29-17-28(24,3)4)32-27(33-26)31-20-11-10-19(16-22(20)38-5)35-12-14-39-15-13-35/h6-11,16,18,34H,12-15,17H2,1-5H3,(H3,29,30,31,32,33)
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Centaurus BioPharma Co., Ltd.

US Patent


Assay Description
To measure inhibitory activity of FAK/PYK2 inhibitors, compounds were first prepare as a 1 mM stock in 100% DMSO and 3-fold serial dilution was perfo...


US Patent US9428508 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM245651
PNG
(US9428508, 106)
Show SMILES CCCNS(=O)(=O)c1ccccc1Nc1nc(Nc2ccc(cc2OC)N2CCOCC2)nc2NCC(C)(C)c12
Show InChI InChI=1S/C28H37N7O4S/c1-5-12-30-40(36,37)23-9-7-6-8-21(23)31-26-24-25(29-18-28(24,2)3)33-27(34-26)32-20-11-10-19(17-22(20)38-4)35-13-15-39-16-14-35/h6-11,17,30H,5,12-16,18H2,1-4H3,(H3,29,31,32,33,34)
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Centaurus BioPharma Co., Ltd.

US Patent


Assay Description
To measure inhibitory activity of FAK/PYK2 inhibitors, compounds were first prepare as a 1 mM stock in 100% DMSO and 3-fold serial dilution was perfo...


US Patent US9428508 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM245652
PNG
(US9428508, 107)
Show SMILES COc1cc(ccc1Nc1nc2NCC(C)(C)c2c(Nc2ccccc2S(=O)(=O)NCC(C)C)n1)N1CCOCC1
Show InChI InChI=1S/C29H39N7O4S/c1-19(2)17-31-41(37,38)24-9-7-6-8-22(24)32-27-25-26(30-18-29(25,3)4)34-28(35-27)33-21-11-10-20(16-23(21)39-5)36-12-14-40-15-13-36/h6-11,16,19,31H,12-15,17-18H2,1-5H3,(H3,30,32,33,34,35)
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Centaurus BioPharma Co., Ltd.

US Patent


Assay Description
To measure inhibitory activity of FAK/PYK2 inhibitors, compounds were first prepare as a 1 mM stock in 100% DMSO and 3-fold serial dilution was perfo...


US Patent US9428508 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM245655
PNG
(US9428508, 110)
Show SMILES CCCCNS(=O)(=O)c1ccccc1Nc1nc(Nc2ccc(cc2OC)N2CCOCC2)nc2NCC(C)(C)c12
Show InChI InChI=1S/C29H39N7O4S/c1-5-6-13-31-41(37,38)24-10-8-7-9-22(24)32-27-25-26(30-19-29(25,2)3)34-28(35-27)33-21-12-11-20(18-23(21)39-4)36-14-16-40-17-15-36/h7-12,18,31H,5-6,13-17,19H2,1-4H3,(H3,30,32,33,34,35)
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Centaurus BioPharma Co., Ltd.

US Patent


Assay Description
To measure inhibitory activity of FAK/PYK2 inhibitors, compounds were first prepare as a 1 mM stock in 100% DMSO and 3-fold serial dilution was perfo...


US Patent US9428508 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM245656
PNG
(US9428508, 111)
Show SMILES COc1cc(ccc1Nc1nc2NCC(C)(C)c2c(Nc2ccccc2S(=O)(=O)N(C)C)n1)N1CCOCC1
Show InChI InChI=1S/C27H35N7O4S/c1-27(2)17-28-24-23(27)25(29-20-8-6-7-9-22(20)39(35,36)33(3)4)32-26(31-24)30-19-11-10-18(16-21(19)37-5)34-12-14-38-15-13-34/h6-11,16H,12-15,17H2,1-5H3,(H3,28,29,30,31,32)
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Centaurus BioPharma Co., Ltd.

US Patent


Assay Description
To measure inhibitory activity of FAK/PYK2 inhibitors, compounds were first prepare as a 1 mM stock in 100% DMSO and 3-fold serial dilution was perfo...


US Patent US9428508 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM245657
PNG
(US9428508, 112)
Show SMILES CCC(C)NS(=O)(=O)c1ccccc1Nc1nc(Nc2ccc(cc2OC)N2CCOCC2)nc2NCC(C)(C)c12
Show InChI InChI=1/C29H39N7O4S/c1-6-19(2)35-41(37,38)24-10-8-7-9-22(24)31-27-25-26(30-18-29(25,3)4)33-28(34-27)32-21-12-11-20(17-23(21)39-5)36-13-15-40-16-14-36/h7-12,17,19,35H,6,13-16,18H2,1-5H3,(H3,30,31,32,33,34)
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Centaurus BioPharma Co., Ltd.

US Patent


Assay Description
To measure inhibitory activity of FAK/PYK2 inhibitors, compounds were first prepare as a 1 mM stock in 100% DMSO and 3-fold serial dilution was perfo...


US Patent US9428508 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM245658
PNG
(US9428508, 113)
Show SMILES CCNS(=O)(=O)c1ccccc1Nc1nc(Nc2ccc(cc2OC)N2CCOCC2)nc2NCC(C)(C)c12
Show InChI InChI=1S/C27H35N7O4S/c1-5-29-39(35,36)22-9-7-6-8-20(22)30-25-23-24(28-17-27(23,2)3)32-26(33-25)31-19-11-10-18(16-21(19)37-4)34-12-14-38-15-13-34/h6-11,16,29H,5,12-15,17H2,1-4H3,(H3,28,30,31,32,33)
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Centaurus BioPharma Co., Ltd.

US Patent


Assay Description
To measure inhibitory activity of FAK/PYK2 inhibitors, compounds were first prepare as a 1 mM stock in 100% DMSO and 3-fold serial dilution was perfo...


US Patent US9428508 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM245659
PNG
(US9428508, 114)
Show SMILES COCCCNS(=O)(=O)c1ccccc1Nc1nc(Nc2ccc(cc2OC)N2CCOCC2)nc2NCC(C)(C)c12
Show InChI InChI=1S/C29H39N7O5S/c1-29(2)19-30-26-25(29)27(32-22-8-5-6-9-24(22)42(37,38)31-12-7-15-39-3)35-28(34-26)33-21-11-10-20(18-23(21)40-4)36-13-16-41-17-14-36/h5-6,8-11,18,31H,7,12-17,19H2,1-4H3,(H3,30,32,33,34,35)
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Centaurus BioPharma Co., Ltd.

US Patent


Assay Description
To measure inhibitory activity of FAK/PYK2 inhibitors, compounds were first prepare as a 1 mM stock in 100% DMSO and 3-fold serial dilution was perfo...


US Patent US9428508 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM245660
PNG
(US9428508, 115)
Show SMILES COCCNS(=O)(=O)c1ccccc1Nc1nc(Nc2ccc(cc2OC)N2CCOCC2)nc2NCC(C)(C)c12
Show InChI InChI=1S/C28H37N7O5S/c1-28(2)18-29-25-24(28)26(31-21-7-5-6-8-23(21)41(36,37)30-11-14-38-3)34-27(33-25)32-20-10-9-19(17-22(20)39-4)35-12-15-40-16-13-35/h5-10,17,30H,11-16,18H2,1-4H3,(H3,29,31,32,33,34)
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Centaurus BioPharma Co., Ltd.

US Patent


Assay Description
To measure inhibitory activity of FAK/PYK2 inhibitors, compounds were first prepare as a 1 mM stock in 100% DMSO and 3-fold serial dilution was perfo...


US Patent US9428508 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM245662
PNG
(US9428508, 117)
Show SMILES COc1cc(ccc1Nc1nc2NCC(C)(C)c2c(Nc2ccccc2S(=O)(=O)NC(C)(C)C)n1)N1CCOCC1
Show InChI InChI=1S/C29H39N7O4S/c1-28(2,3)35-41(37,38)23-10-8-7-9-21(23)31-26-24-25(30-18-29(24,4)5)33-27(34-26)32-20-12-11-19(17-22(20)39-6)36-13-15-40-16-14-36/h7-12,17,35H,13-16,18H2,1-6H3,(H3,30,31,32,33,34)
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Centaurus BioPharma Co., Ltd.

US Patent


Assay Description
To measure inhibitory activity of FAK/PYK2 inhibitors, compounds were first prepare as a 1 mM stock in 100% DMSO and 3-fold serial dilution was perfo...


US Patent US9428508 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM245673
PNG
(US9428508, 128)
Show SMILES CNC(=O)c1ccccc1Nc1nc(Nc2cccc3OCCOc23)nc2NCC(C)(C)c12
Show InChI InChI=1S/C24H26N6O3/c1-24(2)13-26-20-18(24)21(27-15-8-5-4-7-14(15)22(31)25-3)30-23(29-20)28-16-9-6-10-17-19(16)33-12-11-32-17/h4-10H,11-13H2,1-3H3,(H,25,31)(H3,26,27,28,29,30)
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Centaurus BioPharma Co., Ltd.

US Patent


Assay Description
To measure inhibitory activity of FAK/PYK2 inhibitors, compounds were first prepare as a 1 mM stock in 100% DMSO and 3-fold serial dilution was perfo...


US Patent US9428508 (2016)

More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM245676
PNG
(US9428508, 131)
Show SMILES CNC(=O)c1ccccc1Nc1nc(Nc2cccc3ccoc23)nc2NCC(C)(C)c12
Show InChI InChI=1S/C24H24N6O2/c1-24(2)13-26-20-18(24)21(27-16-9-5-4-8-15(16)22(31)25-3)30-23(29-20)28-17-10-6-7-14-11-12-32-19(14)17/h4-12H,13H2,1-3H3,(H,25,31)(H3,26,27,28,29,30)
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Centaurus BioPharma Co., Ltd.

US Patent


Assay Description
To measure inhibitory activity of FAK/PYK2 inhibitors, compounds were first prepare as a 1 mM stock in 100% DMSO and 3-fold serial dilution was perfo...


US Patent US9428508 (2016)

More data for this
Ligand-Target Pair
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