BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 114 hits Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma' AND taxid = 9606   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma


(Homo sapiens)
BDBM50333221
PNG
(6-(pyridin-4-yl)benzo[d]thiazol-2-amine | CHEMBL16...)
Show SMILES Nc1nc2ccc(cc2s1)-c1ccncc1
Show InChI InChI=1S/C12H9N3S/c13-12-15-10-2-1-9(7-11(10)16-12)8-3-5-14-6-4-8/h1-7H,(H2,13,15)
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 2.51E+3n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Inhibition of PIP5K1C (unknown origin) using D-myo-phosphatidylinositol 4-phosphate substrate and ATP by ADP-Glo kinase Assay


Bioorg Med Chem Lett 25: 3189-93 (2015)

More data for this
Ligand-Target Pair
Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma


(Homo sapiens)
BDBM50107268
PNG
(CHEMBL3600693)
Show SMILES CS(=O)(=O)c1ccc(cn1)-c1ccc2nc(N)sc2c1
Show InChI InChI=1S/C13H11N3O2S2/c1-20(17,18)12-5-3-9(7-15-12)8-2-4-10-11(6-8)19-13(14)16-10/h2-7H,1H3,(H2,14,16)
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 1.00E+4n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Inhibition of PIP5K1C (unknown origin) using D-myo-phosphatidylinositol 4-phosphate substrate and ATP by ADP-Glo kinase Assay


Bioorg Med Chem Lett 25: 3189-93 (2015)

More data for this
Ligand-Target Pair
Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma


(Homo sapiens)
BDBM50106970
PNG
(CHEMBL3600767)
Show SMILES Nc1nc2ccc(cc2s1)-c1cc[nH]c(=O)c1
Show InChI InChI=1S/C12H9N3OS/c13-12-15-9-2-1-7(5-10(9)17-12)8-3-4-14-11(16)6-8/h1-6H,(H2,13,15)(H,14,16)
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
AffyNet 
PubMed
n/an/a 1.58E+4n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Inhibition of PIP5K1C (unknown origin) using D-myo-phosphatidylinositol 4-phosphate substrate and ATP by ADP-Glo kinase Assay


Bioorg Med Chem Lett 25: 3189-93 (2015)

More data for this
Ligand-Target Pair
Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma


(Homo sapiens)
BDBM50333219
PNG
(6-(6-methoxypyridin-3-yl)benzo[d]thiazol-2-amine |...)
Show SMILES COc1ccc(cn1)-c1ccc2nc(N)sc2c1
Show InChI InChI=1S/C13H11N3OS/c1-17-12-5-3-9(7-15-12)8-2-4-10-11(6-8)18-13(14)16-10/h2-7H,1H3,(H2,14,16)
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
AffyNet 
PubMed
n/an/a 2.51E+4n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Inhibition of PIP5K1C (unknown origin) using D-myo-phosphatidylinositol 4-phosphate substrate and ATP by ADP-Glo kinase Assay


Bioorg Med Chem Lett 25: 3189-93 (2015)

More data for this
Ligand-Target Pair
Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma


(Homo sapiens)
BDBM50107255
PNG
(CHEMBL3600783)
Show SMILES C[C@H](Nc1nc2ccc(cc2s1)-c1ccn(CC2CC2)c(=O)c1)C1CCOCC1
Show InChI InChI=1/C23H27N3O2S/c1-15(17-7-10-28-11-8-17)24-23-25-20-5-4-18(12-21(20)29-23)19-6-9-26(22(27)13-19)14-16-2-3-16/h4-6,9,12-13,15-17H,2-3,7-8,10-11,14H2,1H3,(H,24,25)/t15-/s2
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 2.51E+4n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Inhibition of PIP5K1C (unknown origin) using D-myo-phosphatidylinositol 4-phosphate substrate and ATP by ADP-Glo kinase Assay


Bioorg Med Chem Lett 25: 3189-93 (2015)

More data for this
Ligand-Target Pair
Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma


(Homo sapiens)
BDBM50107015
PNG
(CHEMBL3600772)
Show SMILES CCCn1cc(cn1)-c1ccc2nc(N)sc2c1
Show InChI InChI=1S/C13H14N4S/c1-2-5-17-8-10(7-15-17)9-3-4-11-12(6-9)18-13(14)16-11/h3-4,6-8H,2,5H2,1H3,(H2,14,16)
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 2.51E+4n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Inhibition of PIP5K1C (unknown origin) using D-myo-phosphatidylinositol 4-phosphate substrate and ATP by ADP-Glo kinase Assay


Bioorg Med Chem Lett 25: 3189-93 (2015)

More data for this
Ligand-Target Pair
Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma


(Homo sapiens)
BDBM50107264
PNG
(CHEMBL3600688)
Show SMILES CCNc1ccc(cn1)-c1ccc2nc(N)sc2c1
Show InChI InChI=1S/C14H14N4S/c1-2-16-13-6-4-10(8-17-13)9-3-5-11-12(7-9)19-14(15)18-11/h3-8H,2H2,1H3,(H2,15,18)(H,16,17)
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 3.16E+4n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Inhibition of PIP5K1C (unknown origin) using D-myo-phosphatidylinositol 4-phosphate substrate and ATP by ADP-Glo kinase Assay


Bioorg Med Chem Lett 25: 3189-93 (2015)

More data for this
Ligand-Target Pair
Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma


(Homo sapiens)
BDBM50106927
PNG
(CHEMBL3600702)
Show SMILES Nc1nc2ccc(cc2s1)-c1ncccn1
Show InChI InChI=1S/C11H8N4S/c12-11-15-8-3-2-7(6-9(8)16-11)10-13-4-1-5-14-10/h1-6H,(H2,12,15)
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
PubMed
n/an/a 3.16E+4n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Inhibition of PIP5K1C (unknown origin) using D-myo-phosphatidylinositol 4-phosphate substrate and ATP by ADP-Glo kinase Assay


Bioorg Med Chem Lett 25: 3189-93 (2015)

More data for this
Ligand-Target Pair
Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma


(Homo sapiens)
BDBM50107276
PNG
(CHEMBL3600696)
Show SMILES CNC(=O)c1ccc(cn1)-c1ccc2nc(N)sc2c1
Show InChI InChI=1S/C14H12N4OS/c1-16-13(19)11-5-3-9(7-17-11)8-2-4-10-12(6-8)20-14(15)18-10/h2-7H,1H3,(H2,15,18)(H,16,19)
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 3.16E+4n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Inhibition of PIP5K1C (unknown origin) using D-myo-phosphatidylinositol 4-phosphate substrate and ATP by ADP-Glo kinase Assay


Bioorg Med Chem Lett 25: 3189-93 (2015)

More data for this
Ligand-Target Pair
Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma


(Homo sapiens)
BDBM50106926
PNG
(CHEMBL3600701)
Show SMILES Nc1nc2ccc(cc2s1)-c1cccnc1
Show InChI InChI=1S/C12H9N3S/c13-12-15-10-4-3-8(6-11(10)16-12)9-2-1-5-14-7-9/h1-7H,(H2,13,15)
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 3.16E+4n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Inhibition of PIP5K1C (unknown origin) using D-myo-phosphatidylinositol 4-phosphate substrate and ATP by ADP-Glo kinase Assay


Bioorg Med Chem Lett 25: 3189-93 (2015)

More data for this
Ligand-Target Pair
Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma


(Homo sapiens)
BDBM50107272
PNG
(CHEMBL3600698)
Show SMILES CC(C)Oc1cncc(c1)-c1ccc2nc(N)sc2c1
Show InChI InChI=1S/C15H15N3OS/c1-9(2)19-12-5-11(7-17-8-12)10-3-4-13-14(6-10)20-15(16)18-13/h3-9H,1-2H3,(H2,16,18)
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 3.16E+4n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Inhibition of PIP5K1C (unknown origin) using D-myo-phosphatidylinositol 4-phosphate substrate and ATP by ADP-Glo kinase Assay


Bioorg Med Chem Lett 25: 3189-93 (2015)

More data for this
Ligand-Target Pair
Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma


(Homo sapiens)
BDBM50106969
PNG
(CHEMBL3600766)
Show SMILES Nc1nc2ccc(cc2s1)-c1ccc(=O)[nH]c1
Show InChI InChI=1S/C12H9N3OS/c13-12-15-9-3-1-7(5-10(9)17-12)8-2-4-11(16)14-6-8/h1-6H,(H2,13,15)(H,14,16)
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 3.98E+4n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Inhibition of PIP5K1C (unknown origin) using D-myo-phosphatidylinositol 4-phosphate substrate and ATP by ADP-Glo kinase Assay


Bioorg Med Chem Lett 25: 3189-93 (2015)

More data for this
Ligand-Target Pair
Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma


(Homo sapiens)
BDBM50107016
PNG
(CHEMBL3600773)
Show SMILES CC(C)n1cc(cn1)-c1ccc2nc(N)sc2c1
Show InChI InChI=1S/C13H14N4S/c1-8(2)17-7-10(6-15-17)9-3-4-11-12(5-9)18-13(14)16-11/h3-8H,1-2H3,(H2,14,16)
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 6.31E+4n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Inhibition of PIP5K1C (unknown origin) using D-myo-phosphatidylinositol 4-phosphate substrate and ATP by ADP-Glo kinase Assay


Bioorg Med Chem Lett 25: 3189-93 (2015)

More data for this
Ligand-Target Pair
Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma


(Homo sapiens)
BDBM50107011
PNG
(CHEMBL3600768)
Show SMILES Cn1ccc(n1)-c1ccc2nc(N)sc2c1
Show InChI InChI=1S/C11H10N4S/c1-15-5-4-8(14-15)7-2-3-9-10(6-7)16-11(12)13-9/h2-6H,1H3,(H2,12,13)
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 6.31E+4n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Inhibition of PIP5K1C (unknown origin) using D-myo-phosphatidylinositol 4-phosphate substrate and ATP by ADP-Glo kinase Assay


Bioorg Med Chem Lett 25: 3189-93 (2015)

More data for this
Ligand-Target Pair
Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma


(Homo sapiens)
BDBM50107243
PNG
(CHEMBL3600779)
Show SMILES Nc1nc2ccc(cc2s1)-c1ccn(CC2CC2)c(=O)c1
Show InChI InChI=1S/C16H15N3OS/c17-16-18-13-4-3-11(7-14(13)21-16)12-5-6-19(15(20)8-12)9-10-1-2-10/h3-8,10H,1-2,9H2,(H2,17,18)
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a<7.94E+4n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Inhibition of PIP5K1C (unknown origin) using D-myo-phosphatidylinositol 4-phosphate substrate and ATP by ADP-Glo kinase Assay


Bioorg Med Chem Lett 25: 3189-93 (2015)

More data for this
Ligand-Target Pair
Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma


(Homo sapiens)
BDBM50107277
PNG
(CHEMBL97245)
Show SMILES Nc1nc2ccc(cc2s1)-c1ccccc1
Show InChI InChI=1S/C13H10N2S/c14-13-15-11-7-6-10(8-12(11)16-13)9-4-2-1-3-5-9/h1-8H,(H2,14,15)
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a<1.00E+5n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Inhibition of PIP5K1C (unknown origin) using D-myo-phosphatidylinositol 4-phosphate substrate and ATP by ADP-Glo kinase Assay


Bioorg Med Chem Lett 25: 3189-93 (2015)

More data for this
Ligand-Target Pair
Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma


(Homo sapiens)
BDBM50107274
PNG
(CHEMBL3600700)
Show SMILES Nc1nc2ccc(cc2s1)-c1ccccn1
Show InChI InChI=1S/C12H9N3S/c13-12-15-10-5-4-8(7-11(10)16-12)9-3-1-2-6-14-9/h1-7H,(H2,13,15)
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a<1.00E+5n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Inhibition of PIP5K1C (unknown origin) using D-myo-phosphatidylinositol 4-phosphate substrate and ATP by ADP-Glo kinase Assay


Bioorg Med Chem Lett 25: 3189-93 (2015)

More data for this
Ligand-Target Pair
Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma


(Homo sapiens)
BDBM50107256
PNG
(CHEMBL3600784)
Show SMILES O=c1cc(ccn1CC1CC1)-c1ccc2nc(NCC3CCS(=O)(=O)CC3)sc2c1
Show InChI InChI=1S/C22H25N3O3S2/c26-21-12-18(5-8-25(21)14-16-1-2-16)17-3-4-19-20(11-17)29-22(24-19)23-13-15-6-9-30(27,28)10-7-15/h3-5,8,11-12,15-16H,1-2,6-7,9-10,13-14H2,(H,23,24)
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a<1.00E+5n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Inhibition of PIP5K1C (unknown origin) using D-myo-phosphatidylinositol 4-phosphate substrate and ATP by ADP-Glo kinase Assay


Bioorg Med Chem Lett 25: 3189-93 (2015)

More data for this
Ligand-Target Pair
Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma


(Homo sapiens)
BDBM50106928
PNG
(CHEMBL3600765)
Show SMILES Nc1nc2ccc(cc2s1)-c1cnccn1
Show InChI InChI=1S/C11H8N4S/c12-11-15-8-2-1-7(5-10(8)16-11)9-6-13-3-4-14-9/h1-6H,(H2,12,15)
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a<1.00E+5n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Inhibition of PIP5K1C (unknown origin) using D-myo-phosphatidylinositol 4-phosphate substrate and ATP by ADP-Glo kinase Assay


Bioorg Med Chem Lett 25: 3189-93 (2015)

More data for this
Ligand-Target Pair
Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma


(Homo sapiens)
BDBM50107258
PNG
(CHEMBL3600683)
Show SMILES CCOc1ccc(cn1)-c1ccc2nc(N)sc2c1
Show InChI InChI=1S/C14H13N3OS/c1-2-18-13-6-4-10(8-16-13)9-3-5-11-12(7-9)19-14(15)17-11/h3-8H,2H2,1H3,(H2,15,17)
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a<1.00E+5n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Inhibition of PIP5K1C (unknown origin) using D-myo-phosphatidylinositol 4-phosphate substrate and ATP by ADP-Glo kinase Assay


Bioorg Med Chem Lett 25: 3189-93 (2015)

More data for this
Ligand-Target Pair
Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma


(Homo sapiens)
BDBM50107012
PNG
(CHEMBL3600769)
Show SMILES Cn1nccc1-c1ccc2nc(N)sc2c1
Show InChI InChI=1S/C11H10N4S/c1-15-9(4-5-13-15)7-2-3-8-10(6-7)16-11(12)14-8/h2-6H,1H3,(H2,12,14)
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a<1.00E+5n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Inhibition of PIP5K1C (unknown origin) using D-myo-phosphatidylinositol 4-phosphate substrate and ATP by ADP-Glo kinase Assay


Bioorg Med Chem Lett 25: 3189-93 (2015)

More data for this
Ligand-Target Pair
Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma


(Homo sapiens)
BDBM50107013
PNG
(CHEMBL3600770)
Show SMILES Cn1cc(cn1)-c1ccc2nc(N)sc2c1
Show InChI InChI=1S/C11H10N4S/c1-15-6-8(5-13-15)7-2-3-9-10(4-7)16-11(12)14-9/h2-6H,1H3,(H2,12,14)
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a<1.00E+5n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Inhibition of PIP5K1C (unknown origin) using D-myo-phosphatidylinositol 4-phosphate substrate and ATP by ADP-Glo kinase Assay


Bioorg Med Chem Lett 25: 3189-93 (2015)

More data for this
Ligand-Target Pair
Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma


(Homo sapiens)
BDBM50107014
PNG
(CHEMBL3600771)
Show SMILES CCn1cc(cn1)-c1ccc2nc(N)sc2c1
Show InChI InChI=1S/C12H12N4S/c1-2-16-7-9(6-14-16)8-3-4-10-11(5-8)17-12(13)15-10/h3-7H,2H2,1H3,(H2,13,15)
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a<1.00E+5n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Inhibition of PIP5K1C (unknown origin) using D-myo-phosphatidylinositol 4-phosphate substrate and ATP by ADP-Glo kinase Assay


Bioorg Med Chem Lett 25: 3189-93 (2015)

More data for this
Ligand-Target Pair
Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma


(Homo sapiens)
BDBM50107254
PNG
(CHEMBL3600782)
Show SMILES C[C@@H](Nc1nc2ccc(cc2s1)-c1ccn(CC2CC2)c(=O)c1)C1CCOCC1
Show InChI InChI=1/C23H27N3O2S/c1-15(17-7-10-28-11-8-17)24-23-25-20-5-4-18(12-21(20)29-23)19-6-9-26(22(27)13-19)14-16-2-3-16/h4-6,9,12-13,15-17H,2-3,7-8,10-11,14H2,1H3,(H,24,25)/t15-/s2
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a<1.00E+5n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Inhibition of PIP5K1C (unknown origin) using D-myo-phosphatidylinositol 4-phosphate substrate and ATP by ADP-Glo kinase Assay


Bioorg Med Chem Lett 25: 3189-93 (2015)

More data for this
Ligand-Target Pair
Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma


(Homo sapiens)
BDBM50107091
PNG
(CHEMBL3600774)
Show SMILES Nc1nc2ccc(cc2s1)-c1cnn(c1)C1CC1
Show InChI InChI=1S/C13H12N4S/c14-13-16-11-4-1-8(5-12(11)18-13)9-6-15-17(7-9)10-2-3-10/h1,4-7,10H,2-3H2,(H2,14,16)
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a<1.00E+5n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Inhibition of PIP5K1C (unknown origin) using D-myo-phosphatidylinositol 4-phosphate substrate and ATP by ADP-Glo kinase Assay


Bioorg Med Chem Lett 25: 3189-93 (2015)

More data for this
Ligand-Target Pair
Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma


(Homo sapiens)
BDBM50107238
PNG
(CHEMBL3600776)
Show SMILES Nc1nc2ccc(cc2s1)-c1cnn(Cc2ccccc2)c1
Show InChI InChI=1S/C17H14N4S/c18-17-20-15-7-6-13(8-16(15)22-17)14-9-19-21(11-14)10-12-4-2-1-3-5-12/h1-9,11H,10H2,(H2,18,20)
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a<1.00E+5n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Inhibition of PIP5K1C (unknown origin) using D-myo-phosphatidylinositol 4-phosphate substrate and ATP by ADP-Glo kinase Assay


Bioorg Med Chem Lett 25: 3189-93 (2015)

More data for this
Ligand-Target Pair
Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma


(Homo sapiens)
BDBM50107241
PNG
(CHEMBL3600777)
Show SMILES Cn1ccc(cc1=O)-c1ccc2nc(N)sc2c1
Show InChI InChI=1S/C13H11N3OS/c1-16-5-4-9(7-12(16)17)8-2-3-10-11(6-8)18-13(14)15-10/h2-7H,1H3,(H2,14,15)
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a<1.00E+5n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Inhibition of PIP5K1C (unknown origin) using D-myo-phosphatidylinositol 4-phosphate substrate and ATP by ADP-Glo kinase Assay


Bioorg Med Chem Lett 25: 3189-93 (2015)

More data for this
Ligand-Target Pair
Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma


(Homo sapiens)
BDBM50107242
PNG
(CHEMBL3600778)
Show SMILES CCn1ccc(cc1=O)-c1ccc2nc(N)sc2c1
Show InChI InChI=1S/C14H13N3OS/c1-2-17-6-5-10(8-13(17)18)9-3-4-11-12(7-9)19-14(15)16-11/h3-8H,2H2,1H3,(H2,15,16)
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a<1.00E+5n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Inhibition of PIP5K1C (unknown origin) using D-myo-phosphatidylinositol 4-phosphate substrate and ATP by ADP-Glo kinase Assay


Bioorg Med Chem Lett 25: 3189-93 (2015)

More data for this
Ligand-Target Pair
Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma


(Homo sapiens)
BDBM50107244
PNG
(CHEMBL3600780)
Show SMILES COCCOn1ccc(cc1=O)-c1ccc2nc(N)sc2c1
Show InChI InChI=1S/C15H15N3O3S/c1-20-6-7-21-18-5-4-11(9-14(18)19)10-2-3-12-13(8-10)22-15(16)17-12/h2-5,8-9H,6-7H2,1H3,(H2,16,17)
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a<1.00E+5n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Inhibition of PIP5K1C (unknown origin) using D-myo-phosphatidylinositol 4-phosphate substrate and ATP by ADP-Glo kinase Assay


Bioorg Med Chem Lett 25: 3189-93 (2015)

More data for this
Ligand-Target Pair
Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma


(Homo sapiens)
BDBM50107248
PNG
(CHEMBL3600781)
Show SMILES O=c1cc(ccn1CC1CC1)-c1ccc2nc(NCC3CCOCC3)sc2c1
Show InChI InChI=1S/C22H25N3O2S/c26-21-12-18(5-8-25(21)14-16-1-2-16)17-3-4-19-20(11-17)28-22(24-19)23-13-15-6-9-27-10-7-15/h3-5,8,11-12,15-16H,1-2,6-7,9-10,13-14H2,(H,23,24)
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a<1.00E+5n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Inhibition of PIP5K1C (unknown origin) using D-myo-phosphatidylinositol 4-phosphate substrate and ATP by ADP-Glo kinase Assay


Bioorg Med Chem Lett 25: 3189-93 (2015)

More data for this
Ligand-Target Pair
Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma


(Homo sapiens)
BDBM50107263
PNG
(CHEMBL3600687)
Show SMILES CC(C)Oc1ccc(cn1)-c1ccc2nc(N)sc2c1
Show InChI InChI=1S/C15H15N3OS/c1-9(2)19-14-6-4-11(8-17-14)10-3-5-12-13(7-10)20-15(16)18-12/h3-9H,1-2H3,(H2,16,18)
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a<1.00E+5n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Inhibition of PIP5K1C (unknown origin) using D-myo-phosphatidylinositol 4-phosphate substrate and ATP by ADP-Glo kinase Assay


Bioorg Med Chem Lett 25: 3189-93 (2015)

More data for this
Ligand-Target Pair
Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma


(Homo sapiens)
BDBM50107262
PNG
(CHEMBL3600686)
Show SMILES CNCc1ccc(cn1)-c1ccc2nc(N)sc2c1
Show InChI InChI=1S/C14H14N4S/c1-16-8-11-4-2-10(7-17-11)9-3-5-12-13(6-9)19-14(15)18-12/h2-7,16H,8H2,1H3,(H2,15,18)
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a<1.00E+5n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Inhibition of PIP5K1C (unknown origin) using D-myo-phosphatidylinositol 4-phosphate substrate and ATP by ADP-Glo kinase Assay


Bioorg Med Chem Lett 25: 3189-93 (2015)

More data for this
Ligand-Target Pair
Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma


(Homo sapiens)
BDBM50107273
PNG
(CHEMBL3600699)
Show SMILES CS(=O)(=O)c1cncc(c1)-c1ccc2nc(N)sc2c1
Show InChI InChI=1S/C13H11N3O2S2/c1-20(17,18)10-4-9(6-15-7-10)8-2-3-11-12(5-8)19-13(14)16-11/h2-7H,1H3,(H2,14,16)
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a<1.00E+5n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Inhibition of PIP5K1C (unknown origin) using D-myo-phosphatidylinositol 4-phosphate substrate and ATP by ADP-Glo kinase Assay


Bioorg Med Chem Lett 25: 3189-93 (2015)

More data for this
Ligand-Target Pair
Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma


(Homo sapiens)
BDBM50107271
PNG
(CHEMBL3600697)
Show SMILES CN(C)C(=O)c1ccc(cn1)-c1ccc2nc(N)sc2c1
Show InChI InChI=1S/C15H14N4OS/c1-19(2)14(20)12-6-4-10(8-17-12)9-3-5-11-13(7-9)21-15(16)18-11/h3-8H,1-2H3,(H2,16,18)
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a<1.00E+5n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Inhibition of PIP5K1C (unknown origin) using D-myo-phosphatidylinositol 4-phosphate substrate and ATP by ADP-Glo kinase Assay


Bioorg Med Chem Lett 25: 3189-93 (2015)

More data for this
Ligand-Target Pair
Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma


(Homo sapiens)
BDBM50107270
PNG
(CHEMBL3600695)
Show SMILES COCCOc1ccc(cn1)-c1ccc2nc(N)sc2c1
Show InChI InChI=1S/C15H15N3O2S/c1-19-6-7-20-14-5-3-11(9-17-14)10-2-4-12-13(8-10)21-15(16)18-12/h2-5,8-9H,6-7H2,1H3,(H2,16,18)
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a<1.00E+5n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Inhibition of PIP5K1C (unknown origin) using D-myo-phosphatidylinositol 4-phosphate substrate and ATP by ADP-Glo kinase Assay


Bioorg Med Chem Lett 25: 3189-93 (2015)

More data for this
Ligand-Target Pair
Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma


(Homo sapiens)
BDBM50107269
PNG
(CHEMBL3600694)
Show SMILES Nc1nc2ccc(cc2s1)-c1ccc(OCCO)nc1
Show InChI InChI=1S/C14H13N3O2S/c15-14-17-11-3-1-9(7-12(11)20-14)10-2-4-13(16-8-10)19-6-5-18/h1-4,7-8,18H,5-6H2,(H2,15,17)
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a<1.00E+5n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Inhibition of PIP5K1C (unknown origin) using D-myo-phosphatidylinositol 4-phosphate substrate and ATP by ADP-Glo kinase Assay


Bioorg Med Chem Lett 25: 3189-93 (2015)

More data for this
Ligand-Target Pair
Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma


(Homo sapiens)
BDBM50107260
PNG
(CHEMBL3600684)
Show SMILES CCSc1ccc(cn1)-c1ccc2nc(N)sc2c1
Show InChI InChI=1S/C14H13N3S2/c1-2-18-13-6-4-10(8-16-13)9-3-5-11-12(7-9)19-14(15)17-11/h3-8H,2H2,1H3,(H2,15,17)
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a<1.00E+5n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Inhibition of PIP5K1C (unknown origin) using D-myo-phosphatidylinositol 4-phosphate substrate and ATP by ADP-Glo kinase Assay


Bioorg Med Chem Lett 25: 3189-93 (2015)

More data for this
Ligand-Target Pair
Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma


(Homo sapiens)
BDBM50107267
PNG
(CHEMBL3600692)
Show SMILES Nc1nc2ccc(cc2s1)-c1ccc(nc1)C(F)(F)F
Show InChI InChI=1S/C13H8F3N3S/c14-13(15,16)11-4-2-8(6-18-11)7-1-3-9-10(5-7)20-12(17)19-9/h1-6H,(H2,17,19)
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
PubMed
n/an/a<1.00E+5n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Inhibition of PIP5K1C (unknown origin) using D-myo-phosphatidylinositol 4-phosphate substrate and ATP by ADP-Glo kinase Assay


Bioorg Med Chem Lett 25: 3189-93 (2015)

More data for this
Ligand-Target Pair
Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma


(Homo sapiens)
BDBM50107266
PNG
(CHEMBL3600691)
Show SMILES Cc1ccc(cn1)-c1ccc2nc(N)sc2c1
Show InChI InChI=1S/C13H11N3S/c1-8-2-3-10(7-15-8)9-4-5-11-12(6-9)17-13(14)16-11/h2-7H,1H3,(H2,14,16)
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a<1.00E+5n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Inhibition of PIP5K1C (unknown origin) using D-myo-phosphatidylinositol 4-phosphate substrate and ATP by ADP-Glo kinase Assay


Bioorg Med Chem Lett 25: 3189-93 (2015)

More data for this
Ligand-Target Pair
Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma


(Homo sapiens)
BDBM50107275
PNG
(CHEMBL3600690)
Show SMILES Nc1nc2ccc(cc2s1)-c1ccc(CO)nc1
Show InChI InChI=1S/C13H11N3OS/c14-13-16-11-4-2-8(5-12(11)18-13)9-1-3-10(7-17)15-6-9/h1-6,17H,7H2,(H2,14,16)
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a<1.00E+5n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Inhibition of PIP5K1C (unknown origin) using D-myo-phosphatidylinositol 4-phosphate substrate and ATP by ADP-Glo kinase Assay


Bioorg Med Chem Lett 25: 3189-93 (2015)

More data for this
Ligand-Target Pair
Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma


(Homo sapiens)
BDBM50107261
PNG
(CHEMBL3600685)
Show SMILES COCc1ccc(cn1)-c1ccc2nc(N)sc2c1
Show InChI InChI=1S/C14H13N3OS/c1-18-8-11-4-2-10(7-16-11)9-3-5-12-13(6-9)19-14(15)17-12/h2-7H,8H2,1H3,(H2,15,17)
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
PubMed
n/an/a<1.00E+5n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Inhibition of PIP5K1C (unknown origin) using D-myo-phosphatidylinositol 4-phosphate substrate and ATP by ADP-Glo kinase Assay


Bioorg Med Chem Lett 25: 3189-93 (2015)

More data for this
Ligand-Target Pair
Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma


(Homo sapiens)
BDBM50107265
PNG
(CHEMBL3600689)
Show SMILES CCN(C)c1ccc(cn1)-c1ccc2nc(N)sc2c1
Show InChI InChI=1S/C15H16N4S/c1-3-19(2)14-7-5-11(9-17-14)10-4-6-12-13(8-10)20-15(16)18-12/h4-9H,3H2,1-2H3,(H2,16,18)
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a<1.00E+5n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Inhibition of PIP5K1C (unknown origin) using D-myo-phosphatidylinositol 4-phosphate substrate and ATP by ADP-Glo kinase Assay


Bioorg Med Chem Lett 25: 3189-93 (2015)

More data for this
Ligand-Target Pair
Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma


(Homo sapiens)
BDBM50355499
PNG
(CHEMBL1908395 | CHEMBL1908842)
Show SMILES CN(C)CC(=O)N1CCC(CC1)c1ccc(NC(=O)c2ncc([nH]2)C#N)c(c1)C1=CCCCC1
Show InChI InChI=1S/C26H32N6O2/c1-31(2)17-24(33)32-12-10-18(11-13-32)20-8-9-23(22(14-20)19-6-4-3-5-7-19)30-26(34)25-28-16-21(15-27)29-25/h6,8-9,14,16,18H,3-5,7,10-13,17H2,1-2H3,(H,28,29)(H,30,34)
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/a>1.00E+4n/an/an/an/an/a



Ambit Biosciences

Curated by ChEMBL


Assay Description
Binding constant for PIP5K1C kinase domain


Citation and Details
More data for this
Ligand-Target Pair
Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma


(Homo sapiens)
BDBM13535
PNG
(4-[6-methoxy-7-(3-piperidin-1-ylpropoxy)quinazolin...)
Show SMILES COc1cc2c(ncnc2cc1OCCCN1CCCCC1)N1CCN(CC1)C(=O)Nc1ccc(OC(C)C)cc1
Show InChI InChI=1S/C31H42N6O4/c1-23(2)41-25-10-8-24(9-11-25)34-31(38)37-17-15-36(16-18-37)30-26-20-28(39-3)29(21-27(26)32-22-33-30)40-19-7-14-35-12-5-4-6-13-35/h8-11,20-23H,4-7,12-19H2,1-3H3,(H,34,38)
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
Article
PubMed
n/an/an/a>1.00E+4n/an/an/an/an/a



Ambit Biosciences

Curated by ChEMBL


Assay Description
Binding constant for PIP5K1C kinase domain


Citation and Details
More data for this
Ligand-Target Pair
Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma


(Homo sapiens)
BDBM13216
PNG
(BMS-354825 | CHEMBL1421 | DASATINIB | N-(2-Chloro-...)
Show SMILES Cc1nc(Nc2ncc(s2)C(=O)Nc2c(C)cccc2Cl)cc(n1)N1CCN(CCO)CC1
Show InChI InChI=1S/C22H26ClN7O2S/c1-14-4-3-5-16(23)20(14)28-21(32)17-13-24-22(33-17)27-18-12-19(26-15(2)25-18)30-8-6-29(7-9-30)10-11-31/h3-5,12-13,31H,6-11H2,1-2H3,(H,28,32)(H,24,25,26,27)
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
UniChem

Patents


Similars

AffyNet 
Article
PubMed
n/an/an/a>1.00E+4n/an/an/an/an/a



Ambit Biosciences

Curated by ChEMBL


Assay Description
Binding constant for PIP5K1C kinase domain


Citation and Details
More data for this
Ligand-Target Pair
Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma


(Homo sapiens)
BDBM50242737
PNG
((R,Z)-5-(2,6-dichlorobenzylsulfonyl)-3-((3,5-dimet...)
Show SMILES Cc1[nH]c(\C=C2/C(=O)Nc3ccc(cc23)S(=O)(=O)Cc2c(Cl)cccc2Cl)c(C)c1C(=O)N1CCC[C@@H]1CN1CCCC1
Show InChI InChI=1S/C32H34Cl2N4O4S/c1-19-29(35-20(2)30(19)32(40)38-14-6-7-21(38)17-37-12-3-4-13-37)16-24-23-15-22(10-11-28(23)36-31(24)39)43(41,42)18-25-26(33)8-5-9-27(25)34/h5,8-11,15-16,21,35H,3-4,6-7,12-14,17-18H2,1-2H3,(H,36,39)/b24-16-/t21-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
Article
PubMed
n/an/an/a>1.00E+4n/an/an/an/an/a



Ambit Biosciences

Curated by ChEMBL


Assay Description
Binding constant for PIP5K1C kinase domain


Citation and Details
More data for this
Ligand-Target Pair
Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma


(Homo sapiens)
BDBM16673
PNG
(4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamo...)
Show SMILES CNC(=O)c1cc(Oc2ccc(NC(=O)Nc3ccc(Cl)c(c3)C(F)(F)F)cc2)ccn1
Show InChI InChI=1S/C21H16ClF3N4O3/c1-26-19(30)18-11-15(8-9-27-18)32-14-5-2-12(3-6-14)28-20(31)29-13-4-7-17(22)16(10-13)21(23,24)25/h2-11H,1H3,(H,26,30)(H2,28,29,31)
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
UniChem

Patents


Similars

AffyNet 
Article
PubMed
n/an/an/a>1.00E+4n/an/an/an/an/a



Ambit Biosciences

Curated by ChEMBL


Assay Description
Binding constant for PIP5K1C kinase domain


Citation and Details
More data for this
Ligand-Target Pair
Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma


(Homo sapiens)
BDBM50322823
PNG
((S)-N-(4-(3-chloro-4-fluorophenylamino)-7-(tetrahy...)
Show SMILES CN(C)C\C=C\C(=O)Nc1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2cc1O[C@H]1CCOC1
Show InChI InChI=1S/C24H25ClFN5O3/c1-31(2)8-3-4-23(32)30-21-11-17-20(12-22(21)34-16-7-9-33-13-16)27-14-28-24(17)29-15-5-6-19(26)18(25)10-15/h3-6,10-12,14,16H,7-9,13H2,1-2H3,(H,30,32)(H,27,28,29)/b4-3+/t16-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
UniChem

Patents


Similars

AffyNet 
Article
PubMed
n/an/an/a>1.00E+4n/an/an/an/an/a



Ambit Biosciences

Curated by ChEMBL


Assay Description
Binding constant for PIP5K1C kinase domain


Citation and Details
More data for this
Ligand-Target Pair
Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma


(Homo sapiens)
BDBM5445
PNG
(CHEMBL554 | GW572016 | LAPATINIB | Lapatinib | N-{...)
Show SMILES CS(=O)(=O)CCNCc1ccc(o1)-c1ccc2ncnc(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c2c1
Show InChI InChI=1S/C29H26ClFN4O4S/c1-40(36,37)12-11-32-16-23-7-10-27(39-23)20-5-8-26-24(14-20)29(34-18-33-26)35-22-6-9-28(25(30)15-22)38-17-19-3-2-4-21(31)13-19/h2-10,13-15,18,32H,11-12,16-17H2,1H3,(H,33,34,35)
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
UniChem

Patents


Similars

AffyNet 
Article
PubMed
n/an/an/a>1.00E+4n/an/an/an/an/a



Ambit Biosciences

Curated by ChEMBL


Assay Description
Binding constant for PIP5K1C kinase domain


Citation and Details
More data for this
Ligand-Target Pair
Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma


(Homo sapiens)
BDBM50161957
PNG
(4-Dimethylamino-but-2-enoic acid {4-[3-chloro-4-(p...)
Show SMILES CCOc1cc2ncc(C#N)c(Nc3ccc(OCc4ccccn4)c(Cl)c3)c2cc1NC(=O)\C=C\CN(C)C
Show InChI InChI=1S/C30H29ClN6O3/c1-4-39-28-16-25-23(15-26(28)36-29(38)9-7-13-37(2)3)30(20(17-32)18-34-25)35-21-10-11-27(24(31)14-21)40-19-22-8-5-6-12-33-22/h5-12,14-16,18H,4,13,19H2,1-3H3,(H,34,35)(H,36,38)/b9-7+
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
Article
PubMed
n/an/an/a>1.00E+4n/an/an/an/an/a



Ambit Biosciences

Curated by ChEMBL


Assay Description
Binding constant for PIP5K1C kinase domain


Citation and Details
More data for this
Ligand-Target Pair
Displayed 1 to 50 (of 114 total )  |  Next  |  Last  >>
Jump to: