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Compile Data Set for Download or QSAR

Found 15 hits Enz. Inhib. hit(s) with Target = 'Placenta growth factor' AND taxid = 10090   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Placenta growth factor


(Mus musculus)
BDBM50339214
PNG
(CHEMBL1689480)
Show SMILES CC[C@H](C)[C@@H]1NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@@H]2CCCN2C(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCNC(=O)COCC(=O)Nc2ccc(CCC(=O)N3CCC3=O)cc2)NC1=O)C(=O)N[C@H]([C@@H](C)O)C(=O)N[C@H](CCCN=C(N)N)C(=O)N[C@H](Cc1ccc(O)cc1)C(N)=O)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](Cc1ccccc1)NC(C)=O)C(C)C
Show InChI InChI=1S/C106H146N26O26S2/c1-9-59(6)89-103(155)119-71(19-13-14-39-112-83(137)51-158-52-84(138)117-66-29-22-62(23-30-66)28-36-85(139)132-42-38-86(132)140)93(145)125-79(43-57(2)3)105(157)131-41-16-21-82(131)101(153)124-78(48-68-50-111-56-115-68)97(149)126-81(100(152)130-90(60(7)133)104(156)120-72(20-15-40-113-106(108)109)92(144)121-74(91(107)143)44-64-24-31-69(135)32-25-64)54-160-159-53-80(99(151)123-77(47-67-49-110-55-114-67)96(148)122-76(98(150)129-89)46-65-26-33-70(136)34-27-65)127-102(154)88(58(4)5)128-94(146)73(35-37-87(141)142)118-95(147)75(116-61(8)134)45-63-17-11-10-12-18-63/h10-12,17-18,22-27,29-34,49-50,55-60,71-82,88-90,133,135-136H,9,13-16,19-21,28,35-48,51-54H2,1-8H3,(H2,107,143)(H,110,114)(H,111,115)(H,112,137)(H,116,134)(H,117,138)(H,118,147)(H,119,155)(H,120,156)(H,121,144)(H,122,148)(H,123,151)(H,124,153)(H,125,145)(H,126,149)(H,127,154)(H,128,146)(H,129,150)(H,130,152)(H,141,142)(H4,108,109,113)/t59-,60+,71-,72+,73-,74+,75-,76-,77-,78-,79-,80-,81-,82-,88-,89-,90+/m0/s1
Reactome pathway
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UniProtKB/SwissProt

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UniChem

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Article
PubMed
n/an/a 0.200n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Inhibition of mouse PlGF-VEGFR-1 interaction by ELISA


Citation and Details
More data for this
Ligand-Target Pair
Placenta growth factor


(Mus musculus)
BDBM50339209
PNG
(CHEMBL1689479)
Show SMILES CC[C@H](C)[C@@H]1NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@@H]2CCCN2C(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCNC(=O)COCC(=O)Nc2ccc(CCC(=O)N3CCC3=O)cc2)NC1=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](Cc1ccccc1)NC(C)=O)C(C)C
Show InChI InChI=1S/C106H146N26O26S2/c1-9-59(6)89-103(155)119-71(19-13-14-39-112-83(137)51-158-52-84(138)117-66-29-22-62(23-30-66)28-36-85(139)132-42-38-86(132)140)93(145)125-79(43-57(2)3)105(157)131-41-16-21-82(131)101(153)124-78(48-68-50-111-56-115-68)97(149)126-81(100(152)130-90(60(7)133)104(156)120-72(20-15-40-113-106(108)109)92(144)121-74(91(107)143)44-64-24-31-69(135)32-25-64)54-160-159-53-80(99(151)123-77(47-67-49-110-55-114-67)96(148)122-76(98(150)129-89)46-65-26-33-70(136)34-27-65)127-102(154)88(58(4)5)128-94(146)73(35-37-87(141)142)118-95(147)75(116-61(8)134)45-63-17-11-10-12-18-63/h10-12,17-18,22-27,29-34,49-50,55-60,71-82,88-90,133,135-136H,9,13-16,19-21,28,35-48,51-54H2,1-8H3,(H2,107,143)(H,110,114)(H,111,115)(H,112,137)(H,116,134)(H,117,138)(H,118,147)(H,119,155)(H,120,156)(H,121,144)(H,122,148)(H,123,151)(H,124,153)(H,125,145)(H,126,149)(H,127,154)(H,128,146)(H,129,150)(H,130,152)(H,141,142)(H4,108,109,113)/t59-,60+,71-,72-,73-,74-,75-,76-,77-,78-,79-,80-,81-,82-,88-,89-,90-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
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CHEMBL
PC cid
PC sid
UniChem

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AffyNet 
Article
PubMed
n/an/a 0.700n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Inhibition of mouse PlGF-VEGFR-1 interaction by ELISA


Citation and Details
More data for this
Ligand-Target Pair
Placenta growth factor


(Mus musculus)
BDBM50339193
PNG
(CHEMBL1689463)
Show SMILES CSCC[C@H](NC(=O)[C@H](CCCCNC(=O)COCC(=O)Nc1ccc(CCC(=O)N2CCC2=O)cc1)NC(=O)[C@H](CCCCNC(C)=O)NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc2ccccc2)NC(C)=O)C(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)N2CCC[C@H]2C(=O)N[C@@H](Cc2cnc[nH]2)C(=O)N1)C(N)=O
Show InChI InChI=1S/C102H144N24O26S3/c1-54(2)41-75-102(151)125-38-20-27-78(125)98(147)118-72(44-64-48-105-53-109-64)92(141)120-76(96(145)114-69(25-16-18-36-106-58(8)128)90(139)113-68(89(138)112-67(88(104)137)35-40-153-10)26-17-19-37-107-80(131)49-152-50-81(132)111-63-31-28-60(29-32-63)30-33-82(133)126-39-34-83(126)134)51-154-155-52-77(121-99(148)85(55(3)4)122-95(144)74(46-84(135)136)117-91(140)70(110-59(9)129)42-61-21-12-11-13-22-61)97(146)116-73(45-79(103)130)93(142)115-71(43-62-47-108-66-24-15-14-23-65(62)66)94(143)123-86(56(5)6)100(149)124-87(57(7)127)101(150)119-75/h11-15,21-24,28-29,31-32,47-48,53-57,67-78,85-87,108,127H,16-20,25-27,30,33-46,49-52H2,1-10H3,(H2,103,130)(H2,104,137)(H,105,109)(H,106,128)(H,107,131)(H,110,129)(H,111,132)(H,112,138)(H,113,139)(H,114,145)(H,115,142)(H,116,146)(H,117,140)(H,118,147)(H,119,150)(H,120,141)(H,121,148)(H,122,144)(H,123,143)(H,124,149)(H,135,136)/t57-,67+,68+,69+,70+,71+,72+,73+,74+,75+,76+,77+,78+,85+,86+,87+/m1/s1
Reactome pathway
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UniProtKB/SwissProt

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UniChem

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Article
PubMed
n/an/a 4n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Inhibition of mouse PlGF-VEGFR-1 interaction by ELISA


Citation and Details
More data for this
Ligand-Target Pair
Placenta growth factor


(Mus musculus)
BDBM50339201
PNG
(CHEMBL1689470)
Show SMILES CSCC[C@H](NC(=O)[C@@H](NC(=O)[C@H](CCCCNC(C)=O)NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc2ccccc2)NC(C)=O)C(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCNC(=O)COCC(=O)Nc2ccc(CCC(=O)N3CCC3=O)cc2)C(=O)N[C@@H](CC(C)C)C(=O)N2CCC[C@H]2C(=O)N[C@@H](Cc2cnc[nH]2)C(=O)N1)C(C)C)C(N)=O
Show InChI InChI=1S/C103H146N24O25S3/c1-55(2)42-76-103(151)126-39-21-28-79(126)99(147)119-73(45-65-49-106-54-110-65)93(141)121-77(97(145)114-70(27-17-19-37-107-59(9)128)91(139)123-86(56(3)4)100(148)113-68(89(105)137)36-41-153-11)52-154-155-53-78(122-102(150)88(58(7)8)125-96(144)75(47-85(135)136)118-92(140)71(111-60(10)129)43-62-22-13-12-14-23-62)98(146)117-74(46-80(104)130)94(142)116-72(44-63-48-109-67-25-16-15-24-66(63)67)95(143)124-87(57(5)6)101(149)115-69(90(138)120-76)26-18-20-38-108-81(131)50-152-51-82(132)112-64-32-29-61(30-33-64)31-34-83(133)127-40-35-84(127)134/h12-16,22-25,29-30,32-33,48-49,54-58,68-79,86-88,109H,17-21,26-28,31,34-47,50-53H2,1-11H3,(H2,104,130)(H2,105,137)(H,106,110)(H,107,128)(H,108,131)(H,111,129)(H,112,132)(H,113,148)(H,114,145)(H,115,149)(H,116,142)(H,117,146)(H,118,140)(H,119,147)(H,120,138)(H,121,141)(H,122,150)(H,123,139)(H,124,143)(H,125,144)(H,135,136)/t68-,69-,70-,71-,72-,73-,74-,75-,76-,77-,78-,79-,86-,87-,88-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
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CHEMBL
PC cid
PC sid
UniChem

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AffyNet 
Article
PubMed
n/an/a 4n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Inhibition of mouse PlGF-VEGFR-1 interaction by ELISA


Citation and Details
More data for this
Ligand-Target Pair
Placenta growth factor


(Mus musculus)
BDBM50339197
PNG
(CHEMBL1689466)
Show SMILES CSCC[C@H](NC(=O)[C@@H](NC(=O)[C@H](CCCCNC(=O)COCC(=O)Nc1ccc(CCC(=O)N2CCC2=O)cc1)NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc2ccccc2)NC(C)=O)C(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)N2CCC[C@H]2C(=O)N[C@@H](Cc2cnc[nH]2)C(=O)N1)C(C)C)C(N)=O
Show InChI InChI=1S/C99H139N23O25S3/c1-51(2)38-71-99(146)121-35-19-25-74(121)94(141)113-68(41-61-45-102-50-105-61)88(135)115-72(92(139)109-65(86(133)117-81(52(3)4)95(142)108-64(85(101)132)33-37-148-11)24-17-18-34-103-76(126)46-147-47-77(127)107-60-29-26-57(27-30-60)28-31-78(128)122-36-32-79(122)129)48-149-150-49-73(116-96(143)82(53(5)6)118-91(138)70(43-80(130)131)112-87(134)66(106-56(10)124)39-58-20-13-12-14-21-58)93(140)111-69(42-75(100)125)89(136)110-67(40-59-44-104-63-23-16-15-22-62(59)63)90(137)119-83(54(7)8)97(144)120-84(55(9)123)98(145)114-71/h12-16,20-23,26-27,29-30,44-45,50-55,64-74,81-84,104,123H,17-19,24-25,28,31-43,46-49H2,1-11H3,(H2,100,125)(H2,101,132)(H,102,105)(H,103,126)(H,106,124)(H,107,127)(H,108,142)(H,109,139)(H,110,136)(H,111,140)(H,112,134)(H,113,141)(H,114,145)(H,115,135)(H,116,143)(H,117,133)(H,118,138)(H,119,137)(H,120,144)(H,130,131)/t55-,64+,65+,66+,67+,68+,69+,70+,71+,72+,73+,74+,81+,82+,83+,84+/m1/s1
Reactome pathway
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UniProtKB/SwissProt

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UniChem

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Article
PubMed
n/an/a 54n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Inhibition of mouse PlGF-VEGFR-1 interaction by ELISA


Citation and Details
More data for this
Ligand-Target Pair
Placenta growth factor


(Mus musculus)
BDBM50339213
PNG
(CHEMBL1689478)
Show SMILES CC[C@H](C)[C@@H]1NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@@H]2CCCN2C(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCN=C(N)N)NC1=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](Cc1ccccc1)NC(C)=O)C(C)C
Show InChI InChI=1S/C90H130N26O21S2/c1-9-48(6)72-86(135)104-59(19-14-32-99-90(94)95)76(125)110-66(34-46(2)3)88(137)116-33-15-20-69(116)84(133)109-65(39-55-41-97-45-101-55)80(129)111-68(83(132)115-73(49(7)117)87(136)105-58(18-13-31-98-89(92)93)75(124)106-61(74(91)123)35-52-21-25-56(119)26-22-52)43-139-138-42-67(82(131)108-64(38-54-40-96-44-100-54)79(128)107-63(81(130)114-72)37-53-23-27-57(120)28-24-53)112-85(134)71(47(4)5)113-77(126)60(29-30-70(121)122)103-78(127)62(102-50(8)118)36-51-16-11-10-12-17-51/h10-12,16-17,21-28,40-41,44-49,58-69,71-73,117,119-120H,9,13-15,18-20,29-39,42-43H2,1-8H3,(H2,91,123)(H,96,100)(H,97,101)(H,102,118)(H,103,127)(H,104,135)(H,105,136)(H,106,124)(H,107,128)(H,108,131)(H,109,133)(H,110,125)(H,111,129)(H,112,134)(H,113,126)(H,114,130)(H,115,132)(H,121,122)(H4,92,93,98)(H4,94,95,99)/t48-,49+,58-,59-,60-,61-,62-,63-,64-,65-,66-,67-,68-,69-,71-,72-,73-/m0/s1
Reactome pathway
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Article
PubMed
n/an/a 400n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Inhibition of mouse PlGF-VEGFR-1 interaction by ELISA


Citation and Details
More data for this
Ligand-Target Pair
Placenta growth factor


(Mus musculus)
BDBM50339204
PNG
(CHEMBL1689473)
Show SMILES CSCC[C@H](NC(=O)[C@@H](NC(=O)[C@H](CCCCNC(C)=O)NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc2ccccc2)NC(C)=O)C(C)C)C(=O)N[C@@H](CCCCNC(=O)COCC(=O)Nc2ccc(CCC(=O)N3CCC3=O)cc2)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)N2CCC[C@H]2C(=O)N[C@@H](Cc2cnc[nH]2)C(=O)N1)C(C)C)C(N)=O
Show InChI InChI=1S/C103H147N23O25S3/c1-55(2)43-76-103(150)125-40-22-29-79(125)98(145)117-74(46-66-49-105-54-109-66)93(140)119-77(96(143)114-71(28-18-20-38-106-60(10)128)91(138)121-85(56(3)4)99(146)112-69(89(104)136)37-42-152-12)52-153-154-53-78(120-100(147)86(57(5)6)122-95(142)75(47-84(134)135)116-92(139)72(110-61(11)129)44-63-23-14-13-15-24-63)97(144)113-70(27-19-21-39-107-80(130)50-151-51-81(131)111-65-33-30-62(31-34-65)32-35-82(132)126-41-36-83(126)133)90(137)115-73(45-64-48-108-68-26-17-16-25-67(64)68)94(141)123-87(58(7)8)101(148)124-88(59(9)127)102(149)118-76/h13-17,23-26,30-31,33-34,48-49,54-59,69-79,85-88,108,127H,18-22,27-29,32,35-47,50-53H2,1-12H3,(H2,104,136)(H,105,109)(H,106,128)(H,107,130)(H,110,129)(H,111,131)(H,112,146)(H,113,144)(H,114,143)(H,115,137)(H,116,139)(H,117,145)(H,118,149)(H,119,140)(H,120,147)(H,121,138)(H,122,142)(H,123,141)(H,124,148)(H,134,135)/t59-,69+,70+,71+,72+,73+,74+,75+,76+,77+,78+,79+,85+,86+,87+,88+/m1/s1
Reactome pathway
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UniProtKB/SwissProt

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UniChem

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AffyNet 
Article
PubMed
n/an/a 624n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Inhibition of mouse PlGF-VEGFR-1 interaction by ELISA


Citation and Details
More data for this
Ligand-Target Pair
Placenta growth factor


(Mus musculus)
BDBM50339205
PNG
(CHEMBL1689474)
Show SMILES CSCC[C@H](NC(=O)[C@@H](NC(=O)[C@H](CCCCNC(C)=O)NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@H](CCCCNC(=O)COCC(=O)Nc2ccc(CCC(=O)N3CCC3=O)cc2)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc2ccccc2)NC(C)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)N2CCC[C@H]2C(=O)N[C@@H](Cc2cnc[nH]2)C(=O)N1)C(C)C)C(N)=O
Show InChI InChI=1S/C102H144N24O26S3/c1-54(2)41-75-102(151)125-38-20-27-78(125)98(147)118-72(44-64-48-105-53-109-64)92(141)121-76(96(145)114-69(26-16-18-36-106-58(8)128)90(139)122-85(55(3)4)99(148)112-67(88(104)137)35-40-153-10)51-154-155-52-77(97(146)116-73(45-79(103)130)93(142)115-71(43-62-47-108-66-24-15-14-23-65(62)66)95(144)123-86(56(5)6)100(149)124-87(57(7)127)101(150)119-75)120-89(138)68(113-94(143)74(46-84(135)136)117-91(140)70(110-59(9)129)42-61-21-12-11-13-22-61)25-17-19-37-107-80(131)49-152-50-81(132)111-63-31-28-60(29-32-63)30-33-82(133)126-39-34-83(126)134/h11-15,21-24,28-29,31-32,47-48,53-57,67-78,85-87,108,127H,16-20,25-27,30,33-46,49-52H2,1-10H3,(H2,103,130)(H2,104,137)(H,105,109)(H,106,128)(H,107,131)(H,110,129)(H,111,132)(H,112,148)(H,113,143)(H,114,145)(H,115,142)(H,116,146)(H,117,140)(H,118,147)(H,119,150)(H,120,138)(H,121,141)(H,122,139)(H,123,144)(H,124,149)(H,135,136)/t57-,67+,68+,69+,70+,71+,72+,73+,74+,75+,76+,77+,78+,85+,86+,87+/m1/s1
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n/an/a>1.00E+3n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Inhibition of mouse PlGF-VEGFR-1 interaction by ELISA


Citation and Details
More data for this
Ligand-Target Pair
Placenta growth factor


(Mus musculus)
BDBM50339202
PNG
(CHEMBL1689471)
Show SMILES CSCC[C@H](NC(=O)[C@@H](NC(=O)[C@H](CCCCNC(C)=O)NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc2ccccc2)NC(C)=O)C(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCNC(=O)COCC(=O)Nc2ccc(CCC(=O)N3CCC3=O)cc2)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)N2CCC[C@H]2C(=O)N[C@@H](Cc2cnc[nH]2)C(=O)N1)C(C)C)C(N)=O
Show InChI InChI=1S/C102H144N24O26S3/c1-54(2)41-75-102(151)125-38-20-27-78(125)98(147)118-72(44-64-48-105-53-109-64)93(142)120-76(96(145)114-68(25-16-18-36-106-58(8)128)89(138)122-85(55(3)4)99(148)112-67(88(104)137)35-40-153-10)51-154-155-52-77(121-100(149)86(56(5)6)123-95(144)74(46-84(135)136)117-91(140)70(110-59(9)129)42-61-21-12-11-13-22-61)97(146)116-73(45-79(103)130)94(143)115-71(43-62-47-108-66-24-15-14-23-65(62)66)92(141)113-69(90(139)124-87(57(7)127)101(150)119-75)26-17-19-37-107-80(131)49-152-50-81(132)111-63-31-28-60(29-32-63)30-33-82(133)126-39-34-83(126)134/h11-15,21-24,28-29,31-32,47-48,53-57,67-78,85-87,108,127H,16-20,25-27,30,33-46,49-52H2,1-10H3,(H2,103,130)(H2,104,137)(H,105,109)(H,106,128)(H,107,131)(H,110,129)(H,111,132)(H,112,148)(H,113,141)(H,114,145)(H,115,143)(H,116,146)(H,117,140)(H,118,147)(H,119,150)(H,120,142)(H,121,149)(H,122,138)(H,123,144)(H,124,139)(H,135,136)/t57-,67+,68+,69+,70+,71+,72+,73+,74+,75+,76+,77+,78+,85+,86+,87+/m1/s1
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n/an/a>1.00E+3n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Inhibition of mouse PlGF-VEGFR-1 interaction by ELISA


Citation and Details
More data for this
Ligand-Target Pair
Placenta growth factor


(Mus musculus)
BDBM50339200
PNG
(CHEMBL1689469)
Show SMILES CSCC[C@H](NC(=O)[C@@H](NC(=O)[C@H](CCCCNC(C)=O)NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc2ccccc2)NC(C)=O)C(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCNC(=O)COCC(=O)Nc2ccc(CCC(=O)N3CCC3=O)cc2)C(=O)N2CCC[C@H]2C(=O)N[C@@H](Cc2cnc[nH]2)C(=O)N1)C(C)C)C(N)=O
Show InChI InChI=1S/C101H142N24O26S3/c1-53(2)83(97(146)111-66(87(103)136)35-40-152-10)120-88(137)67(25-16-18-36-105-57(8)127)112-94(143)74-50-153-154-51-75(119-98(147)84(54(3)4)121-93(142)73(45-82(134)135)116-89(138)69(109-58(9)128)41-60-21-12-11-13-22-60)95(144)115-72(44-77(102)129)91(140)114-70(42-61-46-107-65-24-15-14-23-64(61)65)92(141)122-85(55(5)6)99(148)123-86(56(7)126)100(149)113-68(101(150)124-38-20-27-76(124)96(145)117-71(90(139)118-74)43-63-47-104-52-108-63)26-17-19-37-106-78(130)48-151-49-79(131)110-62-31-28-59(29-32-62)30-33-80(132)125-39-34-81(125)133/h11-15,21-24,28-29,31-32,46-47,52-56,66-76,83-86,107,126H,16-20,25-27,30,33-45,48-51H2,1-10H3,(H2,102,129)(H2,103,136)(H,104,108)(H,105,127)(H,106,130)(H,109,128)(H,110,131)(H,111,146)(H,112,143)(H,113,149)(H,114,140)(H,115,144)(H,116,138)(H,117,145)(H,118,139)(H,119,147)(H,120,137)(H,121,142)(H,122,141)(H,123,148)(H,134,135)/t56-,66+,67+,68+,69+,70+,71+,72+,73+,74+,75+,76+,83+,84+,85+,86+/m1/s1
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n/an/a>1.00E+3n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Inhibition of mouse PlGF-VEGFR-1 interaction by ELISA


Citation and Details
More data for this
Ligand-Target Pair
Placenta growth factor


(Mus musculus)
BDBM50339199
PNG
(CHEMBL1689468)
Show SMILES CSCC[C@H](NC(=O)[C@@H](NC(=O)[C@H](CCCCNC(C)=O)NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc2ccccc2)NC(C)=O)C(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCNC(=O)COCC(=O)Nc2ccc(CCC(=O)N3CCC3=O)cc2)C(=O)N[C@@H](Cc2cnc[nH]2)C(=O)N1)C(C)C)C(N)=O
Show InChI InChI=1S/C102H146N24O26S3/c1-53(2)40-70-91(140)113-68(26-19-21-37-107-79(131)48-152-49-80(132)111-63-31-28-60(29-32-63)30-33-81(133)126-38-34-82(126)134)89(138)116-73(43-64-47-105-52-109-64)93(142)120-76(97(146)114-69(27-18-20-36-106-58(10)128)90(139)122-84(54(3)4)99(148)112-67(88(104)137)35-39-153-12)50-154-155-51-77(121-100(149)85(55(5)6)123-96(145)75(45-83(135)136)118-92(141)71(110-59(11)129)41-61-22-14-13-15-23-61)98(147)117-74(44-78(103)130)94(143)115-72(42-62-46-108-66-25-17-16-24-65(62)66)95(144)124-86(56(7)8)101(150)125-87(57(9)127)102(151)119-70/h13-17,22-25,28-29,31-32,46-47,52-57,67-77,84-87,108,127H,18-21,26-27,30,33-45,48-51H2,1-12H3,(H2,103,130)(H2,104,137)(H,105,109)(H,106,128)(H,107,131)(H,110,129)(H,111,132)(H,112,148)(H,113,140)(H,114,146)(H,115,143)(H,116,138)(H,117,147)(H,118,141)(H,119,151)(H,120,142)(H,121,149)(H,122,139)(H,123,145)(H,124,144)(H,125,150)(H,135,136)/t57-,67+,68+,69+,70+,71+,72+,73+,74+,75+,76+,77+,84+,85+,86+,87+/m1/s1
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n/an/a>1.00E+3n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Inhibition of mouse PlGF-VEGFR-1 interaction by ELISA


Citation and Details
More data for this
Ligand-Target Pair
Placenta growth factor


(Mus musculus)
BDBM50339198
PNG
(CHEMBL1689467)
Show SMILES CSCC[C@H](NC(=O)[C@@H](NC(=O)[C@H](CCCCNC(C)=O)NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc2ccccc2)NC(C)=O)C(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)N2CCC[C@H]2C(=O)N[C@@H](CCCCNC(=O)COCC(=O)Nc2ccc(CCC(=O)N3CCC3=O)cc2)C(=O)N1)C(C)C)C(N)=O
Show InChI InChI=1S/C101H146N22O26S3/c1-53(2)43-73-101(148)122-40-22-29-76(122)96(143)111-67(27-19-21-39-105-78(128)49-149-50-79(129)108-63-33-30-60(31-34-63)32-35-80(130)123-41-36-81(123)131)88(135)116-74(94(141)110-68(28-18-20-38-104-58(10)125)89(136)118-83(54(3)4)97(144)109-66(87(103)134)37-42-150-12)51-151-152-52-75(117-98(145)84(55(5)6)119-93(140)72(47-82(132)133)114-90(137)69(107-59(11)126)44-61-23-14-13-15-24-61)95(142)113-71(46-77(102)127)91(138)112-70(45-62-48-106-65-26-17-16-25-64(62)65)92(139)120-85(56(7)8)99(146)121-86(57(9)124)100(147)115-73/h13-17,23-26,30-31,33-34,48,53-57,66-76,83-86,106,124H,18-22,27-29,32,35-47,49-52H2,1-12H3,(H2,102,127)(H2,103,134)(H,104,125)(H,105,128)(H,107,126)(H,108,129)(H,109,144)(H,110,141)(H,111,143)(H,112,138)(H,113,142)(H,114,137)(H,115,147)(H,116,135)(H,117,145)(H,118,136)(H,119,140)(H,120,139)(H,121,146)(H,132,133)/t57-,66+,67+,68+,69+,70+,71+,72+,73+,74+,75+,76+,83+,84+,85+,86+/m1/s1
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n/an/a>1.00E+3n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Inhibition of mouse PlGF-VEGFR-1 interaction by ELISA


Citation and Details
More data for this
Ligand-Target Pair
Placenta growth factor


(Mus musculus)
BDBM50339203
PNG
(CHEMBL1689472)
Show SMILES CSCC[C@H](NC(=O)[C@@H](NC(=O)[C@H](CCCCNC(C)=O)NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc2ccccc2)NC(C)=O)C(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCCNC(=O)COCC(=O)Nc2ccc(CCC(=O)N3CCC3=O)cc2)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)N2CCC[C@H]2C(=O)N[C@@H](Cc2cnc[nH]2)C(=O)N1)C(C)C)C(N)=O
Show InChI InChI=1S/C96H143N23O26S3/c1-50(2)39-68-96(144)118-36-20-25-71(118)91(139)110-65(41-60-44-99-49-102-60)86(134)112-69(89(137)107-63(23-16-18-34-100-55(10)121)84(132)114-78(51(3)4)92(140)105-61(82(98)130)33-38-146-12)47-147-148-48-70(113-93(141)79(52(5)6)116-88(136)67(43-77(128)129)109-85(133)64(103-56(11)122)40-58-21-14-13-15-22-58)90(138)108-66(42-72(97)123)87(135)106-62(83(131)115-80(53(7)8)94(142)117-81(54(9)120)95(143)111-68)24-17-19-35-101-73(124)45-145-46-74(125)104-59-29-26-57(27-30-59)28-31-75(126)119-37-32-76(119)127/h13-15,21-22,26-27,29-30,44,49-54,61-71,78-81,120H,16-20,23-25,28,31-43,45-48H2,1-12H3,(H2,97,123)(H2,98,130)(H,99,102)(H,100,121)(H,101,124)(H,103,122)(H,104,125)(H,105,140)(H,106,135)(H,107,137)(H,108,138)(H,109,133)(H,110,139)(H,111,143)(H,112,134)(H,113,141)(H,114,132)(H,115,131)(H,116,136)(H,117,142)(H,128,129)/t54-,61+,62+,63+,64+,65+,66+,67+,68+,69+,70+,71+,78+,79+,80+,81+/m1/s1
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n/an/a>1.00E+3n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Inhibition of mouse PlGF-VEGFR-1 interaction by ELISA


Citation and Details
More data for this
Ligand-Target Pair
Placenta growth factor


(Mus musculus)
BDBM50339191
PNG
(CHEMBL1689460)
Show SMILES CSCC[C@H](NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc2ccccc2)NC(C)=O)C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)N2CCC[C@H]2C(=O)N[C@@H](Cc2cnc[nH]2)C(=O)N1)C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NC(=O)COCC(=O)Nc1ccc(CCC(=O)N2CCC2=O)cc1
Show InChI InChI=1S/C107H157N25O25S3/c1-58(2)46-79-107(156)131-43-23-31-82(131)102(151)122-77(49-68-52-111-57-113-68)97(146)124-80(100(149)118-73(30-19-22-42-110)95(144)127-88(59(3)4)103(152)119-74(39-45-158-11)93(142)116-72(29-18-21-41-109)94(143)126-84(136)54-157-53-83(135)115-67-35-32-64(33-36-67)34-37-85(137)132-44-38-86(132)138)55-159-160-56-81(125-104(153)89(60(5)6)128-99(148)78(50-87(139)140)121-96(145)75(114-63(10)134)47-65-24-13-12-14-25-65)101(150)117-71(28-17-20-40-108)92(141)120-76(48-66-51-112-70-27-16-15-26-69(66)70)98(147)129-90(61(7)8)105(154)130-91(62(9)133)106(155)123-79/h12-16,24-27,32-33,35-36,51-52,57-62,71-82,88-91,112,133H,17-23,28-31,34,37-50,53-56,108-110H2,1-11H3,(H,111,113)(H,114,134)(H,115,135)(H,116,142)(H,117,150)(H,118,149)(H,119,152)(H,120,141)(H,121,145)(H,122,151)(H,123,155)(H,124,146)(H,125,153)(H,127,144)(H,128,148)(H,129,147)(H,130,154)(H,139,140)(H,126,136,143)/t62-,71+,72+,73+,74+,75+,76+,77+,78+,79+,80+,81+,82+,88+,89+,90+,91+/m1/s1
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n/an/an/a 400n/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Binding affinity to mouse PlGF


Citation and Details
More data for this
Ligand-Target Pair
Placenta growth factor


(Mus musculus)
BDBM50339212
PNG
(CHEMBL1689483)
Show SMILES CC[C@H](C)[C@@H]1NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@@H](Cc2cnc[nH]2)NC(=O)C(C)(C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCNC(=O)COCC(=O)Nc2ccc(CCC(=O)N3CCC3=O)cc2)NC1=O)C(=O)N[C@H]([C@@H](C)O)C(=O)N[C@@H](CCCCNC(C)=O)C(=O)NC(C)(C)C(N)=O)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)N(C)C(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](C)NC(C)=O)C(C)C
Show InChI InChI=1S/C116H168N28O32S2/c1-18-62(6)94-110(171)128-76(28-23-25-44-121-87(149)54-176-55-88(150)127-72-35-30-69(31-36-72)34-40-89(151)144-45-42-90(144)152)99(160)131-78(46-60(2)3)107(168)142-116(15,16)114(175)137-81(50-74-53-119-59-123-74)102(163)135-85(105(166)140-95(66(10)145)111(172)129-77(29-22-24-43-120-67(11)146)106(167)141-115(13,14)113(117)174)57-178-177-56-84(104(165)133-80(49-73-52-118-58-122-73)101(162)132-79(103(164)139-94)47-71-32-37-75(148)38-33-71)136-109(170)93(61(4)5)138-108(169)86(39-41-91(153)154)143(17)112(173)83(48-70-26-20-19-21-27-70)134-98(159)65(9)125-96(157)64(8)126-100(161)82(51-92(155)156)130-97(158)63(7)124-68(12)147/h19-21,26-27,30-33,35-38,52-53,58-66,76-86,93-95,145,148H,18,22-25,28-29,34,39-51,54-57H2,1-17H3,(H2,117,174)(H,118,122)(H,119,123)(H,120,146)(H,121,149)(H,124,147)(H,125,157)(H,126,161)(H,127,150)(H,128,171)(H,129,172)(H,130,158)(H,131,160)(H,132,162)(H,133,165)(H,134,159)(H,135,163)(H,136,170)(H,137,175)(H,138,169)(H,139,164)(H,140,166)(H,141,167)(H,142,168)(H,153,154)(H,155,156)/t62-,63-,64-,65-,66+,76-,77-,78-,79-,80-,81?,82-,83-,84-,85-,86-,93-,94-,95+/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/a 70n/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Binding affinity to mouse PlGF


Citation and Details
More data for this
Ligand-Target Pair