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Compile Data Set for Download or QSAR

Found 5 hits Enz. Inhib. hit(s) with Target = 'Polymerase acidic protein' AND taxid = 518987   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Polymerase acidic protein


(Influenza B virus (B/Lee/40))
BDBM50409801
PNG
(CHEMBL16525)
Show SMILES OC(=O)c1cccc(NC(=O)Nc2ccc3c(C(=O)c4ccccc4)c(O)n(O)c3c2)c1
Show InChI InChI=1S/C23H17N3O6/c27-20(13-5-2-1-3-6-13)19-17-10-9-16(12-18(17)26(32)21(19)28)25-23(31)24-15-8-4-7-14(11-15)22(29)30/h1-12,28,32H,(H,29,30)(H2,24,25,31)
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

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Article
PubMed
n/an/a 6.00E+3n/an/an/an/an/an/a



Roche Discovery Welwyn

Curated by ChEMBL


Assay Description
Inhibitory concentration against cap-dependent endonuclease activity of influenza B/Lee/40 RNP


Citation and Details
More data for this
Ligand-Target Pair
Polymerase acidic protein


(Influenza B virus (B/Lee/40))
BDBM50409787
PNG
(CHEMBL16377)
Show SMILES CC(=O)c1c(O)n(O)c2cc(NC(=O)c3ccc4ccccc4c3)ccc12
Show InChI InChI=1S/C21H16N2O4/c1-12(24)19-17-9-8-16(11-18(17)23(27)21(19)26)22-20(25)15-7-6-13-4-2-3-5-14(13)10-15/h2-11,26-27H,1H3,(H,22,25)
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 1.80E+4n/an/an/an/an/an/a



Roche Discovery Welwyn

Curated by ChEMBL


Assay Description
Inhibitory concentration against cap-dependent endonuclease activity of influenza B/Lee/40 RNP


Citation and Details
More data for this
Ligand-Target Pair
Polymerase acidic protein


(Influenza B virus (B/Lee/40))
BDBM50409802
PNG
(CHEMBL277536)
Show SMILES Oc1c(C(=O)c2ccccc2)c2ccc(NC(=O)\C=C\c3ccccc3Cl)cc2n1O
Show InChI InChI=1S/C24H17ClN2O4/c25-19-9-5-4-6-15(19)10-13-21(28)26-17-11-12-18-20(14-17)27(31)24(30)22(18)23(29)16-7-2-1-3-8-16/h1-14,30-31H,(H,26,28)/b13-10+
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 2.60E+4n/an/an/an/an/an/a



Roche Discovery Welwyn

Curated by ChEMBL


Assay Description
Inhibitory concentration against cap-dependent endonuclease activity of influenza B/Lee/40 RNP


Citation and Details
More data for this
Ligand-Target Pair
Polymerase acidic protein


(Influenza B virus (B/Lee/40))
BDBM50409780
PNG
(CHEMBL16239)
Show SMILES Oc1c(C(=O)c2ccccc2)c2ccc(NC(=O)c3ccc4ccccc4c3)cc2n1O
Show InChI InChI=1S/C26H18N2O4/c29-24(17-7-2-1-3-8-17)23-21-13-12-20(15-22(21)28(32)26(23)31)27-25(30)19-11-10-16-6-4-5-9-18(16)14-19/h1-15,31-32H,(H,27,30)
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 2.90E+4n/an/an/an/an/an/a



Roche Discovery Welwyn

Curated by ChEMBL


Assay Description
Inhibitory concentration against cap-dependent endonuclease activity of influenza B/Lee/40 RNP


Citation and Details
More data for this
Ligand-Target Pair
Polymerase acidic protein


(Influenza B virus (B/Lee/40))
BDBM50409792
PNG
(CHEMBL275631)
Show SMILES Oc1c(C(=O)c2ccccc2)c2ccc(NC(=O)c3ccccc3)cc2n1O
Show InChI InChI=1S/C22H16N2O4/c25-20(14-7-3-1-4-8-14)19-17-12-11-16(13-18(17)24(28)22(19)27)23-21(26)15-9-5-2-6-10-15/h1-13,27-28H,(H,23,26)
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 5.60E+4n/an/an/an/an/an/a



Roche Discovery Welwyn

Curated by ChEMBL


Assay Description
Inhibitory concentration against cap-dependent endonuclease activity of influenza B/Lee/40 RNP


Citation and Details
More data for this
Ligand-Target Pair