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Found 16 hits Enz. Inhib. hit(s) with Target = 'Potassium channel (ATP modulatory)' AND taxid = 9823   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Potassium channel (ATP modulatory)


(GUINEA PIG)
BDBM86244
PNG
(A-312110)
Show SMILES Fc1ccc(cc1I)[C@@H]1C2C(=O)COCC2=NC2=C1S(=O)(=O)CC2
Show InChI InChI=1S/C16H13FINO4S/c17-9-2-1-8(5-10(9)18)14-15-12(6-23-7-13(15)20)19-11-3-4-24(21,22)16(11)14/h1-2,5,14-15H,3-4,6-7H2/t14-,15?/m1/s1
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4.90n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by PDSP Ki Database




Mol Pharmacol 64: 143-53 (2003)

More data for this
Ligand-Target Pair
Potassium channel (ATP modulatory)


(GUINEA PIG)
BDBM86250
PNG
(CAS_60559-98-0 | NSC_43345 | P1075)
Show SMILES CCC(C)(C)N=C(NC#N)Nc1cccnc1
Show InChI InChI=1S/C12H17N5/c1-4-12(2,3)17-11(15-9-13)16-10-6-5-7-14-8-10/h5-8H,4H2,1-3H3,(H2,15,16,17)
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10.5n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by PDSP Ki Database




Mol Pharmacol 64: 143-53 (2003)

More data for this
Ligand-Target Pair
Potassium channel (ATP modulatory)


(GUINEA PIG)
BDBM86250
PNG
(CAS_60559-98-0 | NSC_43345 | P1075)
Show SMILES CCC(C)(C)N=C(NC#N)Nc1cccnc1
Show InChI InChI=1S/C12H17N5/c1-4-12(2,3)17-11(15-9-13)16-10-6-5-7-14-8-10/h5-8H,4H2,1-3H3,(H2,15,16,17)
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10.7n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by PDSP Ki Database




Br J Pharmacol 143: 81-90 (2004)

More data for this
Ligand-Target Pair
Potassium channel (ATP modulatory)


(GUINEA PIG)
BDBM86247
PNG
(BAY X 9228 | CAS_3038059 | NSC_3038059)
Show SMILES CCOc1ccccc1N=C(C[N+]([O-])=O)NC(C)C(C)(C)C
Show InChI InChI=1S/C16H25N3O3/c1-6-22-14-10-8-7-9-13(14)18-15(11-19(20)21)17-12(2)16(3,4)5/h7-10,12H,6,11H2,1-5H3,(H,17,18)
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16n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by PDSP Ki Database




Mol Pharmacol 64: 143-53 (2003)

More data for this
Ligand-Target Pair
Potassium channel (ATP modulatory)


(GUINEA PIG)
BDBM86250
PNG
(CAS_60559-98-0 | NSC_43345 | P1075)
Show SMILES CCC(C)(C)N=C(NC#N)Nc1cccnc1
Show InChI InChI=1S/C12H17N5/c1-4-12(2,3)17-11(15-9-13)16-10-6-5-7-14-8-10/h5-8H,4H2,1-3H3,(H2,15,16,17)
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20.6n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by PDSP Ki Database




Mol Pharmacol 64: 143-53 (2003)

More data for this
Ligand-Target Pair
Potassium channel (ATP modulatory)


(GUINEA PIG)
BDBM86247
PNG
(BAY X 9228 | CAS_3038059 | NSC_3038059)
Show SMILES CCOc1ccccc1N=C(C[N+]([O-])=O)NC(C)C(C)(C)C
Show InChI InChI=1S/C16H25N3O3/c1-6-22-14-10-8-7-9-13(14)18-15(11-19(20)21)17-12(2)16(3,4)5/h7-10,12H,6,11H2,1-5H3,(H,17,18)
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41.3n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by PDSP Ki Database




Mol Pharmacol 64: 143-53 (2003)

More data for this
Ligand-Target Pair
Potassium channel (ATP modulatory)


(GUINEA PIG)
BDBM86245
PNG
(CAS_85371-64-8 | NSC_4826 | PINACIDIL)
Show SMILES CC(N=C(NC#N)Nc1ccncc1)C(C)(C)C
Show InChI InChI=1S/C13H19N5/c1-10(13(2,3)4)17-12(16-9-14)18-11-5-7-15-8-6-11/h5-8,10H,1-4H3,(H2,15,16,17,18)
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104n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by PDSP Ki Database




Mol Pharmacol 64: 143-53 (2003)

More data for this
Ligand-Target Pair
Potassium channel (ATP modulatory)


(GUINEA PIG)
BDBM86251
PNG
(CAS_94535-50-9 | CROMAKALIM (-) | NSC_93504)
Show SMILES CC1(C)Oc2ccc(cc2C(C1O)N1CCCC1=O)C#N
Show InChI InChI=1S/C16H18N2O3/c1-16(2)15(20)14(18-7-3-4-13(18)19)11-8-10(9-17)5-6-12(11)21-16/h5-6,8,14-15,20H,3-4,7H2,1-2H3
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157n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by PDSP Ki Database




Mol Pharmacol 64: 143-53 (2003)

More data for this
Ligand-Target Pair
Potassium channel (ATP modulatory)


(GUINEA PIG)
BDBM86245
PNG
(CAS_85371-64-8 | NSC_4826 | PINACIDIL)
Show SMILES CC(N=C(NC#N)Nc1ccncc1)C(C)(C)C
Show InChI InChI=1S/C13H19N5/c1-10(13(2,3)4)17-12(16-9-14)18-11-5-7-15-8-6-11/h5-8,10H,1-4H3,(H2,15,16,17,18)
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251n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by PDSP Ki Database




Mol Pharmacol 64: 143-53 (2003)

More data for this
Ligand-Target Pair
Potassium channel (ATP modulatory)


(GUINEA PIG)
BDBM86249
PNG
(ZD 6169 | ZD-6169)
Show SMILES C[C@](O)(C(=O)Nc1ccc(cc1)C(=O)c1ccccc1)C(F)(F)F
Show InChI InChI=1S/C17H14F3NO3/c1-16(24,17(18,19)20)15(23)21-13-9-7-12(8-10-13)14(22)11-5-3-2-4-6-11/h2-10,24H,1H3,(H,21,23)/t16-/m0/s1
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451n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by PDSP Ki Database




Mol Pharmacol 64: 143-53 (2003)

More data for this
Ligand-Target Pair
Potassium channel (ATP modulatory)


(GUINEA PIG)
BDBM86251
PNG
(CAS_94535-50-9 | CROMAKALIM (-) | NSC_93504)
Show SMILES CC1(C)Oc2ccc(cc2C(C1O)N1CCCC1=O)C#N
Show InChI InChI=1S/C16H18N2O3/c1-16(2)15(20)14(18-7-3-4-13(18)19)11-8-10(9-17)5-6-12(11)21-16/h5-6,8,14-15,20H,3-4,7H2,1-2H3
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542n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by PDSP Ki Database




Mol Pharmacol 64: 143-53 (2003)

More data for this
Ligand-Target Pair
Potassium channel (ATP modulatory)


(GUINEA PIG)
BDBM86249
PNG
(ZD 6169 | ZD-6169)
Show SMILES C[C@](O)(C(=O)Nc1ccc(cc1)C(=O)c1ccccc1)C(F)(F)F
Show InChI InChI=1S/C17H14F3NO3/c1-16(24,17(18,19)20)15(23)21-13-9-7-12(8-10-13)14(22)11-5-3-2-4-6-11/h2-10,24H,1H3,(H,21,23)/t16-/m0/s1
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630n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by PDSP Ki Database




Mol Pharmacol 64: 143-53 (2003)

More data for this
Ligand-Target Pair
Potassium channel (ATP modulatory)


(GUINEA PIG)
BDBM86246
PNG
(zm244085)
Show SMILES O=C1CCCC2=NC3=C(C(C12)c1cccc(c1)C#N)C(=O)CCC3
Show InChI InChI=1S/C20H18N2O2/c21-11-12-4-1-5-13(10-12)18-19-14(6-2-8-16(19)23)22-15-7-3-9-17(24)20(15)18/h1,4-5,10,18-19H,2-3,6-9H2
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671n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by PDSP Ki Database




Mol Pharmacol 64: 143-53 (2003)

More data for this
Ligand-Target Pair
Potassium channel (ATP modulatory)


(GUINEA PIG)
BDBM86246
PNG
(zm244085)
Show SMILES O=C1CCCC2=NC3=C(C(C12)c1cccc(c1)C#N)C(=O)CCC3
Show InChI InChI=1S/C20H18N2O2/c21-11-12-4-1-5-13(10-12)18-19-14(6-2-8-16(19)23)22-15-7-3-9-17(24)20(15)18/h1,4-5,10,18-19H,2-3,6-9H2
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2.77E+3n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by PDSP Ki Database




Mol Pharmacol 64: 143-53 (2003)

More data for this
Ligand-Target Pair
Potassium channel (ATP modulatory)


(GUINEA PIG)
BDBM86248
PNG
(CAS_364-98-7 | DIAZOXIDE | NSC_3019 | diazoxide)
Show SMILES CC1=Nc2ccc(Cl)cc2S(=O)(=O)N1
Show InChI InChI=1S/C8H7ClN2O2S/c1-5-10-7-3-2-6(9)4-8(7)14(12,13)11-5/h2-4H,1H3,(H,10,11)
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>1.00E+4n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by PDSP Ki Database




Mol Pharmacol 64: 143-53 (2003)

More data for this
Ligand-Target Pair
Potassium channel (ATP modulatory)


(GUINEA PIG)
BDBM86248
PNG
(CAS_364-98-7 | DIAZOXIDE | NSC_3019 | diazoxide)
Show SMILES CC1=Nc2ccc(Cl)cc2S(=O)(=O)N1
Show InChI InChI=1S/C8H7ClN2O2S/c1-5-10-7-3-2-6(9)4-8(7)14(12,13)11-5/h2-4H,1H3,(H,10,11)
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>1.00E+4n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by PDSP Ki Database




Mol Pharmacol 64: 143-53 (2003)

More data for this
Ligand-Target Pair