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Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Prenyl protein specific protease' AND taxid = 9606   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Prenyl protein specific protease


(Homo sapiens)
BDBM50096860
PNG
((E)-3-Biphenyl-4-yl-N-{2-[3-(2,3-dimethyl-phenylsu...)
Show SMILES Cc1cccc(NS(=O)(=O)c2cccc(NC(=O)CCNC(=O)\C=C\c3ccc(cc3)-c3ccccc3)c2)c1C
Show InChI InChI=1S/C32H31N3O4S/c1-23-8-6-13-30(24(23)2)35-40(38,39)29-12-7-11-28(22-29)34-32(37)20-21-33-31(36)19-16-25-14-17-27(18-15-25)26-9-4-3-5-10-26/h3-19,22,35H,20-21H2,1-2H3,(H,33,36)(H,34,37)/b19-16+
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
AffyNet 
PubMed
n/an/a 7.00E+3n/an/an/an/an/an/a



Philipps-Universität Marburg

Curated by ChEMBL


Assay Description
Inhibition of recombinant prenyl protein-specific protease Rce1 expressed in Sf9 cells at 10 uM


Bioorg Med Chem Lett 11: 425-7 (2001)

More data for this
Ligand-Target Pair
Prenyl protein specific protease


(Homo sapiens)
BDBM50096861
PNG
(CHEMBL440905 | Heptadecanoic acid {[3-(2,3-dimethy...)
Show SMILES CCCCCCCCCCCCCCCCC(=O)NCC(=O)Nc1cccc(c1)S(=O)(=O)Nc1cccc(C)c1C
Show InChI InChI=1S/C33H51N3O4S/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-24-32(37)34-26-33(38)35-29-21-19-22-30(25-29)41(39,40)36-31-23-18-20-27(2)28(31)3/h18-23,25,36H,4-17,24,26H2,1-3H3,(H,34,37)(H,35,38)
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 7.00E+3n/an/an/an/an/an/a



Philipps-Universität Marburg

Curated by ChEMBL


Assay Description
Inhibition of recombinant prenyl protein-specific protease Rce1 expressed in Sf9 cells at 10 uM


Bioorg Med Chem Lett 11: 425-7 (2001)

More data for this
Ligand-Target Pair
Prenyl protein specific protease


(Homo sapiens)
BDBM50096862
PNG
((9Z,12Z)-Octadeca-9,12-dienoic acid {2-[3-(2,3-dim...)
Show SMILES CCCCC\C=C/C\C=C/CCCCCCCC(=O)NCCC(=O)Nc1cccc(c1)S(=O)(=O)Nc1cccc(C)c1C
Show InChI InChI=1S/C35H51N3O4S/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-25-34(39)36-27-26-35(40)37-31-22-20-23-32(28-31)43(41,42)38-33-24-19-21-29(2)30(33)3/h8-9,11-12,19-24,28,38H,4-7,10,13-18,25-27H2,1-3H3,(H,36,39)(H,37,40)/b9-8-,12-11-
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 1.40E+4n/an/an/an/an/an/a



Philipps-Universität Marburg

Curated by ChEMBL


Assay Description
Inhibition of recombinant prenyl protein-specific protease Rcel expressed in Sf9 cells


Bioorg Med Chem Lett 11: 425-7 (2001)

More data for this
Ligand-Target Pair