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Compile Data Set for Download or QSAR

Found 21 hits Enz. Inhib. hit(s) with Target = 'Probable G-protein coupled receptor 139' AND taxid = 9606   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Probable G-protein coupled receptor 139


(Homo sapiens)
BDBM50131895
PNG
(CHEMBL3633896)
Show SMILES C[C@@H](NC(=O)CNC(=O)c1cccc(Cl)c1)c1ccccc1
UniProtKB/SwissProt

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PubMed
n/an/an/an/a 2.10E+3n/an/an/an/a



Janssen Research& Development, LLC

Curated by ChEMBL


Assay Description
Binding affinity against delta opioid receptor in mouse hot plate test


ACS Med Chem Lett 6: 1015-8 (2015)

More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 139


(Homo sapiens)
BDBM50132143
PNG
(CHEMBL3633720)
Show SMILES C[C@H](NC(=O)CNC(=O)c1cccc(Cl)c1)c1ccccc1
UniProtKB/SwissProt

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PubMed
n/an/an/an/a 16n/an/an/an/a



Janssen Research& Development, LLC

Curated by ChEMBL


Assay Description
Inhibition of [3H]-U-69,593 binding to Opioid receptor kappa 1


ACS Med Chem Lett 6: 1015-8 (2015)

More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 139


(Homo sapiens)
BDBM50131897
PNG
(CHEMBL3633894)
Show SMILES CC(NC(=O)CSC(=O)c1ccccc1)c1ccccc1
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PubMed
n/an/an/an/a 670n/an/an/an/a



Janssen Research& Development, LLC

Curated by ChEMBL


Assay Description
Binding affinity against delta opioid receptor in mouse hot plate test


ACS Med Chem Lett 6: 1015-8 (2015)

More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 139


(Homo sapiens)
BDBM50131899
PNG
(CHEMBL3633893)
Show SMILES COc1cc(OC)cc(c1)C(=O)NNC(=O)Nc1cccc2ccccc12
UniProtKB/SwissProt

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PubMed
n/an/an/an/a 43n/an/an/an/a



Janssen Research& Development, LLC

Curated by ChEMBL


Assay Description
Binding affinity against delta opioid receptor in mouse hot plate test


ACS Med Chem Lett 6: 1015-8 (2015)

More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 139


(Homo sapiens)
BDBM50131900
PNG
(CHEMBL3633892)
Show SMILES C[C@H](NC(=O)CNCc1cccc(Cl)c1)c1ccccc1
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PubMed
n/an/an/an/a>1.00E+4n/an/an/an/a



Janssen Research& Development, LLC

Curated by ChEMBL


Assay Description
Binding affinity against delta opioid receptor in mouse hot plate test


ACS Med Chem Lett 6: 1015-8 (2015)

More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 139


(Homo sapiens)
BDBM50131901
PNG
(CHEMBL3633891)
Show SMILES C[C@H](NCCNC(=O)c1cccc(Cl)c1)c1ccccc1
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PubMed
n/an/an/an/a>1.00E+4n/an/an/an/a



Janssen Research& Development, LLC

Curated by ChEMBL


Assay Description
Binding affinity against delta opioid receptor in mouse hot plate test


ACS Med Chem Lett 6: 1015-8 (2015)

More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 139


(Homo sapiens)
BDBM50131902
PNG
(CHEMBL3633890)
Show SMILES COc1cc(OC)cc(c1)C(=O)NCC(=O)N[C@@H](C)c1ccccc1
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PubMed
n/an/an/an/a 32n/an/an/an/a



Janssen Research& Development, LLC

Curated by ChEMBL


Assay Description
Binding affinity against delta opioid receptor in mouse hot plate test


ACS Med Chem Lett 6: 1015-8 (2015)

More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 139


(Homo sapiens)
BDBM50131903
PNG
(CHEMBL3633889)
Show SMILES C[C@H](NC(=O)CNC(=O)c1cc(Cl)cc(Br)c1)c1ccccc1
UniProtKB/SwissProt

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PubMed
n/an/an/an/a 78n/an/an/an/a



Janssen Research& Development, LLC

Curated by ChEMBL


Assay Description
Binding affinity against delta opioid receptor in mouse hot plate test


ACS Med Chem Lett 6: 1015-8 (2015)

More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 139


(Homo sapiens)
BDBM50131904
PNG
(CHEMBL3633888)
Show SMILES C[C@H](NC(=O)CNC(=O)c1cc(F)cc(Cl)c1)c1ccccc1
UniProtKB/SwissProt

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PubMed
n/an/an/an/a 24n/an/an/an/a



Janssen Research& Development, LLC

Curated by ChEMBL


Assay Description
Inhibition of [3H]-FPP incorporation into H-ras CVLS by farnesyltransferase


ACS Med Chem Lett 6: 1015-8 (2015)

More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 139


(Homo sapiens)
BDBM50131905
PNG
(CHEMBL3633887)
Show SMILES C[C@H](NC(=O)CNC(=O)c1cc(Cl)cc(Cl)c1)c1ccccc1
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PubMed
n/an/an/an/a 46n/an/an/an/a



Janssen Research& Development, LLC

Curated by ChEMBL


Assay Description
Inhibition of [3H]-FPP incorporation into H-ras CVLS by farnesyltransferase


ACS Med Chem Lett 6: 1015-8 (2015)

More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 139


(Homo sapiens)
BDBM50131906
PNG
(CHEMBL3633886)
Show SMILES C[C@H](NC(=O)CNC(=O)c1cc(Cl)ccc1Cl)c1ccccc1
UniProtKB/SwissProt

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PubMed
n/an/an/an/a 40n/an/an/an/a



Janssen Research& Development, LLC

Curated by ChEMBL


Assay Description
Inhibition of [3H]-FPP incorporation into H-ras CVLS by farnesyltransferase


ACS Med Chem Lett 6: 1015-8 (2015)

More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 139


(Homo sapiens)
BDBM50131931
PNG
(CHEMBL3633885)
Show SMILES C[C@H](NC(=O)CNC(=O)c1ccc(Cl)c(Cl)c1)c1ccccc1
UniProtKB/SwissProt

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PubMed
n/an/an/an/a 193n/an/an/an/a



Janssen Research& Development, LLC

Curated by ChEMBL


Assay Description
Inhibition of [3H]-FPP incorporation into H-ras CVLS by farnesyltransferase


ACS Med Chem Lett 6: 1015-8 (2015)

More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 139


(Homo sapiens)
BDBM50131946
PNG
(CHEMBL3633884)
Show SMILES C[C@H](NC(=O)CNC(=O)c1cccc(Cl)c1Cl)c1ccccc1
UniProtKB/SwissProt

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PubMed
n/an/an/an/a 52n/an/an/an/a



Janssen Research& Development, LLC

Curated by ChEMBL


Assay Description
Inhibition of [3H]-FPP incorporation into H-ras CVLS by farnesyltransferase


ACS Med Chem Lett 6: 1015-8 (2015)

More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 139


(Homo sapiens)
BDBM50131993
PNG
(CHEMBL3633883)
Show SMILES C[C@H](NC(=O)CNC(=O)c1cccc(OC(F)(F)F)c1)c1ccccc1
UniProtKB/SwissProt

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PubMed
n/an/an/an/a 46n/an/an/an/a



Janssen Research& Development, LLC

Curated by ChEMBL


Assay Description
Inhibition of [3H]-U-69,593 binding to Opioid receptor kappa 1


ACS Med Chem Lett 6: 1015-8 (2015)

More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 139


(Homo sapiens)
BDBM50131994
PNG
(CHEMBL3633882)
Show SMILES C[C@H](NC(=O)CNC(=O)c1cccc(c1)C(F)(F)F)c1ccccc1
UniProtKB/SwissProt

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n/an/an/an/a 52n/an/an/an/a



Janssen Research& Development, LLC

Curated by ChEMBL


Assay Description
Inhibition of [3H]-U-69,593 binding to Opioid receptor kappa 1


ACS Med Chem Lett 6: 1015-8 (2015)

More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 139


(Homo sapiens)
BDBM50131999
PNG
(CHEMBL3633881)
Show SMILES COc1cccc(c1)C(=O)NCC(=O)N[C@@H](C)c1ccccc1
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PubMed
n/an/an/an/a 33n/an/an/an/a



Janssen Research& Development, LLC

Curated by ChEMBL


Assay Description
Inhibition of [3H]-U-69,593 binding to Opioid receptor kappa 1


ACS Med Chem Lett 6: 1015-8 (2015)

More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 139


(Homo sapiens)
BDBM50132000
PNG
(CHEMBL3633880)
Show SMILES C[C@H](NC(=O)CNC(=O)c1cccc(F)c1)c1ccccc1
UniProtKB/SwissProt

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PubMed
n/an/an/an/a 54n/an/an/an/a



Janssen Research& Development, LLC

Curated by ChEMBL


Assay Description
Inhibition of [3H]-U-69,593 binding to Opioid receptor kappa 1


ACS Med Chem Lett 6: 1015-8 (2015)

More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 139


(Homo sapiens)
BDBM50132131
PNG
(CHEMBL3633879)
Show SMILES C[C@H](NC(=O)CNC(=O)c1cccc(c1)C#N)c1ccccc1
UniProtKB/SwissProt

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PubMed
n/an/an/an/a 59n/an/an/an/a



Janssen Research& Development, LLC

Curated by ChEMBL


Assay Description
Inhibition of [3H]-U-69,593 binding to Opioid receptor kappa 1


ACS Med Chem Lett 6: 1015-8 (2015)

More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 139


(Homo sapiens)
BDBM50132137
PNG
(CHEMBL3633878)
Show SMILES C[C@H](NC(=O)CNC(=O)c1cccc(C)c1)c1ccccc1
UniProtKB/SwissProt

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CHEMBL
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PubMed
n/an/an/an/a 24n/an/an/an/a



Janssen Research& Development, LLC

Curated by ChEMBL


Assay Description
Inhibition of [3H]-U-69,593 binding to Opioid receptor kappa 1


ACS Med Chem Lett 6: 1015-8 (2015)

More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 139


(Homo sapiens)
BDBM50132141
PNG
(CHEMBL3633721)
Show SMILES C[C@H](NC(=O)CNC(=O)c1ccc(Cl)cc1)c1ccccc1
UniProtKB/SwissProt

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PubMed
n/an/an/an/a 118n/an/an/an/a



Janssen Research& Development, LLC

Curated by ChEMBL


Assay Description
Inhibition of [3H]-U-69,593 binding to Opioid receptor kappa 1


ACS Med Chem Lett 6: 1015-8 (2015)

More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 139


(Homo sapiens)
BDBM50131896
PNG
(CHEMBL3633895)
Show SMILES COc1cccc(c1)C(=O)NCC(=O)N[C@H](C)c1ccccc1
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PubMed
n/an/an/an/a 1.70E+3n/an/an/an/a



Janssen Research& Development, LLC

Curated by ChEMBL


Assay Description
Binding affinity against delta opioid receptor in mouse hot plate test


ACS Med Chem Lett 6: 1015-8 (2015)

More data for this
Ligand-Target Pair