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Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'Probable G-protein coupled receptor 142' AND taxid = 10090   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Probable G-protein coupled receptor 142


(Mus musculus)
BDBM50395775
PNG
(CHEMBL2164857)
Show SMILES CNc1cc(ccn1)-c1nnc(NC(=O)[C@H](Cc2ccccc2)NCc2cscn2)s1
Show InChI InChI=1S/C21H21N7OS2/c1-22-18-10-15(7-8-23-18)20-27-28-21(31-20)26-19(29)17(9-14-5-3-2-4-6-14)24-11-16-12-30-13-25-16/h2-8,10,12-13,17,24H,9,11H2,1H3,(H,22,23)(H,26,28,29)/t17-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

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Article
PubMed
n/an/a 15n/an/an/an/an/an/a



Amgen Inc

Curated by ChEMBL


Assay Description
Partial agonist activity at mouse GPR142 expressed in HEK293 cells


Citation and Details
More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 142


(Mus musculus)
BDBM50440693
PNG
(CHEMBL2430983)
Show SMILES Cn1nc(cc1NC(=O)[C@H](Cc1ccccc1)NCC(O)=O)-c1ccncc1
Show InChI InChI=1S/C20H21N5O3/c1-25-18(12-16(24-25)15-7-9-21-10-8-15)23-20(28)17(22-13-19(26)27)11-14-5-3-2-4-6-14/h2-10,12,17,22H,11,13H2,1H3,(H,23,28)(H,26,27)/t17-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
n/an/an/an/a 31n/an/an/an/a


TBA

Assay Description
Agonist activity at mouse GPR142


Citation and Details
More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 142


(Mus musculus)
BDBM50395776
PNG
(CHEMBL2164850)
Show SMILES O=C(Nc1cc(c[nH]c1=O)-c1ccncc1)[C@H](Cc1ccccc1)NC1(CC1)c1ccccn1
Show InChI InChI=1S/C27H25N5O2/c33-25-22(17-21(18-30-25)20-9-14-28-15-10-20)31-26(34)23(16-19-6-2-1-3-7-19)32-27(11-12-27)24-8-4-5-13-29-24/h1-10,13-15,17-18,23,32H,11-12,16H2,(H,30,33)(H,31,34)/t23-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 1.80n/an/an/an/a



Amgen Inc

Curated by ChEMBL


Assay Description
Agonist activity at mouse GPR142 expressed in HEK293 cells by inositol phosphate accumulation assay


Citation and Details
More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 142


(Mus musculus)
BDBM50390577
PNG
(CHEMBL2069482)
Show SMILES N[C@@H](Cc1ccccc1)C(=O)Nc1cc(c[nH]c1=O)-c1ccncc1
Show InChI InChI=1S/C19H18N4O2/c20-16(10-13-4-2-1-3-5-13)18(24)23-17-11-15(12-22-19(17)25)14-6-8-21-9-7-14/h1-9,11-12,16H,10,20H2,(H,22,25)(H,23,24)/t16-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 1.40E+3n/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Agonist activity at mouse GPR142 assessed as inositol phosphate accumulation


Citation and Details
More data for this
Ligand-Target Pair