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Found 6 hits Enz. Inhib. hit(s) with Target = 'Programmed cell death 1 ligand 1' AND taxid = 9606   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Programmed cell death 1 ligand 1


(Homo sapiens)
BDBM50091334
PNG
(CHEMBL3582252)
Show SMILES COc1cc(OCc2cccc(c2C)-c2ccccc2)cc(OC)c1CN1CCCC[C@H]1C(O)=O
Show InChI InChI=1/C29H33NO5/c1-20-22(12-9-13-24(20)21-10-5-4-6-11-21)19-35-23-16-27(33-2)25(28(17-23)34-3)18-30-15-8-7-14-26(30)29(31)32/h4-6,9-13,16-17,26H,7-8,14-15,18-19H2,1-3H3,(H,31,32)/t26-/s2
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PubMed
n/an/a 6n/an/an/an/an/an/a



Therachem Research Medilab (India) Pvt. Ltd.

Curated by ChEMBL


Assay Description
Binding affinity to His-tagged PD-L1 (unknown origin) assessed as inhibition of interaction with PD1 preincubated for 15 mins followed by PD1 additio...


Citation and Details
More data for this
Ligand-Target Pair
Programmed cell death 1 ligand 1


(Homo sapiens)
BDBM50091332
PNG
(CHEMBL3582254)
Show SMILES C[C@@H](NCc1ccc(OCc2cccc(c2C)-c2ccccc2)c(Cl)c1)C(O)=O
Show InChI InChI=1/C24H24ClNO3/c1-16-20(9-6-10-21(16)19-7-4-3-5-8-19)15-29-23-12-11-18(13-22(23)25)14-26-17(2)24(27)28/h3-13,17,26H,14-15H2,1-2H3,(H,27,28)/t17-/s2
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PubMed
n/an/a 6n/an/an/an/an/an/a



Therachem Research Medilab (India) Pvt. Ltd.

Curated by ChEMBL


Assay Description
Binding affinity to His-tagged PD-L1 (unknown origin) assessed as inhibition of interaction with PD1 preincubated for 15 mins followed by PD1 additio...


Citation and Details
More data for this
Ligand-Target Pair
Programmed cell death 1 ligand 1


(Homo sapiens)
BDBM50091330
PNG
(CHEMBL3582256)
Show SMILES COc1cc(OCc2cccc(-c3ccccc3)c2C#N)cc(OC)c1CN1CCCC[C@H]1C(O)=O
Show InChI InChI=1/C29H30N2O5/c1-34-27-15-22(16-28(35-2)25(27)18-31-14-7-6-13-26(31)29(32)33)36-19-21-11-8-12-23(24(21)17-30)20-9-4-3-5-10-20/h3-5,8-12,15-16,26H,6-7,13-14,18-19H2,1-2H3,(H,32,33)/t26-/s2
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UniChem

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Article
PubMed
n/an/a 6n/an/an/an/an/an/a



Therachem Research Medilab (India) Pvt. Ltd.

Curated by ChEMBL


Assay Description
Binding affinity to His-tagged PD-L1 (unknown origin) assessed as inhibition of interaction with PD1 preincubated for 15 mins followed by PD1 additio...


Citation and Details
More data for this
Ligand-Target Pair
Programmed cell death 1 ligand 1


(Homo sapiens)
BDBM50091329
PNG
(CHEMBL3582257)
Show SMILES COc1cc(OCc2cccc(c2C)-c2ccccc2)cc(OC)c1CNC(CO)(CO)CO
Show InChI InChI=1S/C27H33NO6/c1-19-21(10-7-11-23(19)20-8-5-4-6-9-20)15-34-22-12-25(32-2)24(26(13-22)33-3)14-28-27(16-29,17-30)18-31/h4-13,28-31H,14-18H2,1-3H3
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Article
PubMed
n/an/a 6n/an/an/an/an/an/a



Therachem Research Medilab (India) Pvt. Ltd.

Curated by ChEMBL


Assay Description
Binding affinity to His-tagged PD-L1 (unknown origin) assessed as inhibition of interaction with PD1 preincubated for 15 mins followed by PD1 additio...


Citation and Details
More data for this
Ligand-Target Pair
Programmed cell death 1 ligand 1


(Homo sapiens)
BDBM50091333
PNG
(CHEMBL3582253)
Show SMILES Cc1cc(CN2CCC(CC2)C(=O)NCCO)ccc1OCc1cccc(c1C)-c1ccccc1
Show InChI InChI=1S/C30H36N2O3/c1-22-19-24(20-32-16-13-26(14-17-32)30(34)31-15-18-33)11-12-29(22)35-21-27-9-6-10-28(23(27)2)25-7-4-3-5-8-25/h3-12,19,26,33H,13-18,20-21H2,1-2H3,(H,31,34)
PDB

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PC cid
PC sid
UniChem

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Article
PubMed
n/an/a 11n/an/an/an/an/an/a



Therachem Research Medilab (India) Pvt. Ltd.

Curated by ChEMBL


Assay Description
Binding affinity to His-tagged PD-L1 (unknown origin) assessed as inhibition of interaction with PD1 preincubated for 15 mins followed by PD1 additio...


Citation and Details
More data for this
Ligand-Target Pair
Programmed cell death 1 ligand 1


(Homo sapiens)
BDBM50091331
PNG
(CHEMBL3582255)
Show SMILES Cc1c(COc2ccc(CNCC3CCC(=O)N3)cc2)cccc1-c1ccccc1
Show InChI InChI=1/C26H28N2O2/c1-19-22(8-5-9-25(19)21-6-3-2-4-7-21)18-30-24-13-10-20(11-14-24)16-27-17-23-12-15-26(29)28-23/h2-11,13-14,23,27H,12,15-18H2,1H3,(H,28,29)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 101n/an/an/an/an/an/a



Therachem Research Medilab (India) Pvt. Ltd.

Curated by ChEMBL


Assay Description
Binding affinity to His-tagged PD-L1 (unknown origin) assessed as inhibition of interaction with PD1 preincubated for 15 mins followed by PD1 additio...


Citation and Details
More data for this
Ligand-Target Pair