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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Prostaglandin E receptor 4' AND taxid = 9615   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Prostaglandin E receptor 4


(Canis lupus familiaris)
BDBM50107283
PNG
(AAT-007 | CJ-023 | GRAPIPRANT | Grapiprant | MR-10...)
Show SMILES CCc1nc2c(C)nc(C)cc2n1-c1ccc(CCNC(=O)NS(=O)(=O)c2ccc(C)cc2)cc1
Show InChI InChI=1S/C26H29N5O3S/c1-5-24-29-25-19(4)28-18(3)16-23(25)31(24)21-10-8-20(9-11-21)14-15-27-26(32)30-35(33,34)22-12-6-17(2)7-13-22/h6-13,16H,5,14-15H2,1-4H3,(H2,27,30,32)
GoogleScholar
Purchase

PC cid
PC sid
UniChem

Similars

Article
PubMed
24n/an/an/an/an/an/an/an/a



AskAt Inc.

Curated by ChEMBL


Assay Description
Antagonist activity at dog recombinant EP4 receptor


Bioorg Med Chem Lett 27: 1186-1192 (2017)


Article DOI: 10.1016/j.bmcl.2017.01.067
More data for this
Ligand-Target Pair
Prostaglandin E receptor 4


(Canis lupus familiaris)
BDBM50232544
PNG
(CHEMBL4099851)
Show SMILES C[C@H](NC(=O)c1cc(Cl)cnc1Oc1cccc(F)c1)c1ccc(cc1)C(O)=O
Show InChI InChI=1S/C21H16ClFN2O4/c1-12(13-5-7-14(8-6-13)21(27)28)25-19(26)18-9-15(22)11-24-20(18)29-17-4-2-3-16(23)10-17/h2-12H,1H3,(H,25,26)(H,27,28)/t12-/m0/s1
GoogleScholar
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
38n/an/an/an/an/an/an/an/a



AskAt Inc.

Curated by ChEMBL


Assay Description
Antagonist activity at dog recombinant EP4 receptor


Bioorg Med Chem Lett 27: 1186-1192 (2017)


Article DOI: 10.1016/j.bmcl.2017.01.067
More data for this
Ligand-Target Pair