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Found 40 hits Enz. Inhib. hit(s) with Target = 'Prostaglandin transporter (PGT)' AND taxid = 10116   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Prostaglandin transporter (PGT)


(Rattus norvegicus (Rat))
BDBM10042
PNG
((5Z)-7-[(1R,4S,5R,6R)-6-[(1E,3S)-3-hydroxyoct-1-en...)
Show SMILES CCCCC[C@H](O)\C=C\[C@H]1[C@H]2C[C@H](OO2)[C@@H]1C\C=C/CCCC(O)=O
Show InChI InChI=1S/C20H32O5/c1-2-3-6-9-15(21)12-13-17-16(18-14-19(17)25-24-18)10-7-4-5-8-11-20(22)23/h4,7,12-13,15-19,21H,2-3,5-6,8-11,14H2,1H3,(H,22,23)/b7-4-,13-12+/t15-,16+,17+,18-,19+/m0/s1
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38.2n/an/an/an/an/an/an/an/a



Albert Einstein College of Medicine

Curated by ChEMBL


Assay Description
TP_TRANSPORTER: inhibition of PGE2 uptake in PGT-expressing HeLa cells


Mol Pharmacol 50: 738-42 (1996)

More data for this
Ligand-Target Pair
Prostaglandin transporter (PGT)


(Rattus norvegicus (Rat))
BDBM50035622
PNG
((5Z,13E,15S)-9alpha,11alpha,15-trihydroxyprosta-5,...)
Show SMILES CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)C[C@H](O)[C@@H]1C\C=C/CCCC(O)=O
Show InChI InChI=1S/C20H34O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,12-13,15-19,21-23H,2-3,5-6,8-11,14H2,1H3,(H,24,25)/b7-4-,13-12+/t15-,16+,17+,18-,19+/m0/s1
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45n/an/an/an/an/an/an/an/a



Albert Einstein College of Medicine

Curated by ChEMBL


Assay Description
TP_TRANSPORTER: inhibition of PGE2 uptake in PGT-expressing HeLa cells


Am J Physiol 277: 734-41 (1999)

More data for this
Ligand-Target Pair
Prostaglandin transporter (PGT)


(Rattus norvegicus (Rat))
BDBM21544
PNG
((5Z)-7-[(1R,2R,5S)-5-hydroxy-2-[(1E,3S)-3-hydroxyo...)
Show SMILES CCCCC[C@H](O)\C=C\[C@@H]1[C@@H](C\C=C/CCCC(O)=O)[C@@H](O)CC1=O
Show InChI InChI=1S/C20H32O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,12-13,15-18,21-22H,2-3,5-6,8-11,14H2,1H3,(H,24,25)/b7-4-,13-12+/t15-,16+,17+,18-/m0/s1
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45n/an/an/an/an/an/an/an/a



Albert Einstein College of Medicine

Curated by ChEMBL


Assay Description
TP_TRANSPORTER: inhibition of PGE2 uptake in PGT-expressing HeLa cells


Am J Physiol 277: 734-41 (1999)

More data for this
Ligand-Target Pair
Prostaglandin transporter (PGT)


(Rattus norvegicus (Rat))
BDBM50390997
PNG
(CHEMBL1561148)
Show SMILES CCCCC[C@H](O)C=CC1=C(CCCCCCC(O)=O)C(=O)CC1
Show InChI InChI=1S/C20H32O4/c1-2-3-6-9-17(21)14-12-16-13-15-19(22)18(16)10-7-4-5-8-11-20(23)24/h12,14,17,21H,2-11,13,15H2,1H3,(H,23,24)/t17-/m0/s1
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71.2n/an/an/an/an/an/an/an/a



Albert Einstein College of Medicine

Curated by ChEMBL


Assay Description
TP_TRANSPORTER: inhibition of PGE2 uptake in PGT-expressing HeLa cells


Mol Pharmacol 50: 738-42 (1996)

More data for this
Ligand-Target Pair
Prostaglandin transporter (PGT)


(Rattus norvegicus (Rat))
BDBM50390998
PNG
(CHEMBL2075005)
Show SMILES CCCCC[C@H](O)\C=C\[C@@H]1[C@@H](CCCCCCC(O)=O)[C@@H](O)CC1=O
Show InChI InChI=1S/C20H34O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h12-13,15-18,21-22H,2-11,14H2,1H3,(H,24,25)/b13-12+/t15-,16+,17+,18-/m0/s1
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162n/an/an/an/an/an/an/an/a



Albert Einstein College of Medicine

Curated by ChEMBL


Assay Description
TP_TRANSPORTER: inhibition of PGE2 uptake in PGT-expressing HeLa cells


Mol Pharmacol 50: 738-42 (1996)

More data for this
Ligand-Target Pair
Prostaglandin transporter (PGT)


(Rattus norvegicus (Rat))
BDBM50318491
PNG
(7-((1R,2S)-2-((S)-3-hydroxyoct-1-enyl)-5-oxocyclop...)
Show SMILES CCCCC[C@H](O)C=C[C@H]1C=CC(=O)[C@@H]1CCCCCCC(O)=O
Show InChI InChI=1S/C20H32O4/c1-2-3-6-9-17(21)14-12-16-13-15-19(22)18(16)10-7-4-5-8-11-20(23)24/h12-18,21H,2-11H2,1H3,(H,23,24)/t16-,17-,18+/m0/s1
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286n/an/an/an/an/an/an/an/a



Albert Einstein College of Medicine

Curated by ChEMBL


Assay Description
TP_TRANSPORTER: inhibition of PGE2 uptake in PGT-expressing HeLa cells


Mol Pharmacol 50: 738-42 (1996)

More data for this
Ligand-Target Pair
Prostaglandin transporter (PGT)


(Rattus norvegicus (Rat))
BDBM50420251
PNG
(CHEMBL145704)
Show SMILES Cc1c(Br)c(O)c(Br)cc1C1(OS(=O)(=O)c2ccccc12)c1cc(Br)c(O)c(Br)c1C
Show InChI InChI=1S/C21H14Br4O5S/c1-9-12(7-14(22)19(26)17(9)24)21(13-8-15(23)20(27)18(25)10(13)2)11-5-3-4-6-16(11)31(28,29)30-21/h3-8,26-27H,1-2H3
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3.60E+3n/an/an/an/an/an/an/an/a



Albert Einstein College of Medicine

Curated by ChEMBL


Assay Description
TP_TRANSPORTER: inhibition of PGF2alpha uptake in PGT-expressing HeLa cells


Citation and Details
More data for this
Ligand-Target Pair
Prostaglandin transporter (PGT)


(Rattus norvegicus (Rat))
BDBM50390979
PNG
(BROMOSULFOPHTHALEIN)
Show SMILES Oc1ccc(cc1S([O-])(=O)=O)C1(OC(=O)c2c1c(Br)c(Br)c(Br)c2Br)c1ccc(O)c(c1)S([O-])(=O)=O
Show InChI InChI=1S/C20H10Br4O10S2/c21-15-13-14(16(22)18(24)17(15)23)20(34-19(13)27,7-1-3-9(25)11(5-7)35(28,29)30)8-2-4-10(26)12(6-8)36(31,32)33/h1-6,25-26H,(H,28,29,30)(H,31,32,33)/p-2
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5.80E+3n/an/an/an/an/an/an/an/a



Albert Einstein College of Medicine

Curated by ChEMBL


Assay Description
TP_TRANSPORTER: inhibition of PGF2alpha uptake in PGT-expressing HeLa cells


Citation and Details
More data for this
Ligand-Target Pair
Prostaglandin transporter (PGT)


(Rattus norvegicus (Rat))
BDBM50420250
PNG
(INDOCYANINE GREEN)
Show SMILES CC1(C)\C(=C\C=C\C=C\C=C\C2=[N+](CCCCS([O-])(=O)=O)c3ccc4ccccc4c3C2(C)C)N(CCCCS(O)(=O)=O)c2ccc3ccccc3c12
Show InChI InChI=1S/C43H48N2O6S2/c1-42(2)38(44(28-14-16-30-52(46,47)48)36-26-24-32-18-10-12-20-34(32)40(36)42)22-8-6-5-7-9-23-39-43(3,4)41-35-21-13-11-19-33(35)25-27-37(41)45(39)29-15-17-31-53(49,50)51/h5-13,18-27H,14-17,28-31H2,1-4H3,(H-,46,47,48,49,50,51)
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3.50E+4n/an/an/an/an/an/an/an/a



Albert Einstein College of Medicine

Curated by ChEMBL


Assay Description
TP_TRANSPORTER: inhibition of PGF2alpha uptake in PGT-expressing HeLa cells


Citation and Details
More data for this
Ligand-Target Pair
Prostaglandin transporter (PGT)


(Rattus norvegicus (Rat))
BDBM25902
PNG
(4-chloro-2-[(furan-2-ylmethyl)amino]-5-sulfamoylbe...)
Show SMILES NS(=O)(=O)c1cc(C(O)=O)c(NCc2ccco2)cc1Cl
Show InChI InChI=1S/C12H11ClN2O5S/c13-9-5-10(15-6-7-2-1-3-20-7)8(12(16)17)4-11(9)21(14,18)19/h1-5,15H,6H2,(H,16,17)(H2,14,18,19)
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4.70E+4n/an/an/an/an/an/an/an/a



Albert Einstein College of Medicine

Curated by ChEMBL


Assay Description
TP_TRANSPORTER: inhibition of PGF2alpha uptake in PGT-expressing HeLa cells


Citation and Details
More data for this
Ligand-Target Pair
Prostaglandin transporter (PGT)


(Rattus norvegicus (Rat))
BDBM144817
PNG
(US8952150, 143)
Show SMILES Oc1ccc(Nc2nc(NCCOCCOCCNC(=O)c3ccccc3)nc(Nc3ccc(cc3)C(=O)NCc3ccc(F)cc3)n2)cc1F
Show InChI InChI=1S/C36H36F2N8O5/c37-27-10-6-24(7-11-27)23-41-33(49)26-8-12-28(13-9-26)42-35-44-34(45-36(46-35)43-29-14-15-31(47)30(38)22-29)40-17-19-51-21-20-50-18-16-39-32(48)25-4-2-1-3-5-25/h1-15,22,47H,16-21,23H2,(H,39,48)(H,41,49)(H3,40,42,43,44,45,46)
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n/an/a 16.5n/an/an/an/an/an/a



Albert Einstein College of Medicine of Yeshiva University

US Patent


Assay Description
MDCK cells stably transfected with rat PGT (Endo et al., 2002) were seeded at 15-20% confluence on 24-well plates. The day on which the cells were se...


US Patent US8952150 (2015)

More data for this
Ligand-Target Pair
Prostaglandin transporter (PGT)


(Rattus norvegicus (Rat))
BDBM144813
PNG
(US8952150, 118)
Show SMILES Oc1ccc(Nc2nc(NCCOCCNC(=O)c3ccccc3)nc(Nc3ccc(cc3)C(=O)NCc3ccccc3)n2)cc1
Show InChI InChI=1S/C34H34N8O4/c43-29-17-15-28(16-18-29)39-34-41-32(36-20-22-46-21-19-35-30(44)25-9-5-2-6-10-25)40-33(42-34)38-27-13-11-26(12-14-27)31(45)37-23-24-7-3-1-4-8-24/h1-18,43H,19-23H2,(H,35,44)(H,37,45)(H3,36,38,39,40,41,42)
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n/an/a 20.9n/an/an/an/an/an/a



Albert Einstein College of Medicine of Yeshiva University

US Patent


Assay Description
MDCK cells stably transfected with rat PGT (Endo et al., 2002) were seeded at 15-20% confluence on 24-well plates. The day on which the cells were se...


US Patent US8952150 (2015)

More data for this
Ligand-Target Pair
Prostaglandin transporter (PGT)


(Rattus norvegicus (Rat))
BDBM144810
PNG
(US8952150, 99)
Show SMILES Oc1ccc(Nc2nc(NCCOCCOCCNC(=O)c3ccccc3)nc(Nc3ccc(cc3)C(=O)NCc3ccc(F)cc3)n2)cc1
Show InChI InChI=1S/C36H37FN8O5/c37-28-10-6-25(7-11-28)24-40-33(48)27-8-12-29(13-9-27)41-35-43-34(44-36(45-35)42-30-14-16-31(46)17-15-30)39-19-21-50-23-22-49-20-18-38-32(47)26-4-2-1-3-5-26/h1-17,46H,18-24H2,(H,38,47)(H,40,48)(H3,39,41,42,43,44,45)
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n/an/a 23.7n/an/an/an/an/an/a



Albert Einstein College of Medicine of Yeshiva University

US Patent


Assay Description
MDCK cells stably transfected with rat PGT (Endo et al., 2002) were seeded at 15-20% confluence on 24-well plates. The day on which the cells were se...


US Patent US8952150 (2015)

More data for this
Ligand-Target Pair
Prostaglandin transporter (PGT)


(Rattus norvegicus (Rat))
BDBM144815
PNG
(US8952150, 136)
Show SMILES Oc1ccc(Nc2nc(NCCOCCNC(=O)c3ccc(F)cc3)nc(Nc3ccc(cc3)C(=O)NCc3ccccc3)n2)cc1
Show InChI InChI=1S/C34H33FN8O4/c35-26-10-6-24(7-11-26)30(45)36-18-20-47-21-19-37-32-41-33(43-34(42-32)40-28-14-16-29(44)17-15-28)39-27-12-8-25(9-13-27)31(46)38-22-23-4-2-1-3-5-23/h1-17,44H,18-22H2,(H,36,45)(H,38,46)(H3,37,39,40,41,42,43)
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n/an/a 23.9n/an/an/an/an/an/a



Albert Einstein College of Medicine of Yeshiva University

US Patent


Assay Description
MDCK cells stably transfected with rat PGT (Endo et al., 2002) were seeded at 15-20% confluence on 24-well plates. The day on which the cells were se...


US Patent US8952150 (2015)

More data for this
Ligand-Target Pair
Prostaglandin transporter (PGT)


(Rattus norvegicus (Rat))
BDBM144812
PNG
(US8952150, 110)
Show SMILES Oc1ccc(Nc2nc(NCCOCCOCCNC(=O)c3ccccc3)nc(Nc3ccc(cc3)C(=O)NCc3ccccc3F)n2)cc1
Show InChI InChI=1S/C36H37FN8O5/c37-31-9-5-4-8-27(31)24-40-33(48)26-10-12-28(13-11-26)41-35-43-34(44-36(45-35)42-29-14-16-30(46)17-15-29)39-19-21-50-23-22-49-20-18-38-32(47)25-6-2-1-3-7-25/h1-17,46H,18-24H2,(H,38,47)(H,40,48)(H3,39,41,42,43,44,45)
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n/an/a 31.3n/an/an/an/an/an/a



Albert Einstein College of Medicine of Yeshiva University

US Patent


Assay Description
MDCK cells stably transfected with rat PGT (Endo et al., 2002) were seeded at 15-20% confluence on 24-well plates. The day on which the cells were se...


US Patent US8952150 (2015)

More data for this
Ligand-Target Pair
Prostaglandin transporter (PGT)


(Rattus norvegicus (Rat))
BDBM144819
PNG
(US8952150, 147)
Show SMILES Oc1ccc(Nc2nc(NCCOCCNC(=O)c3ccccc3)nc(Nc3ccc(cc3)C(=O)NCc3ccc(F)cc3)n2)cc1
Show InChI InChI=1S/C34H33FN8O4/c35-26-10-6-23(7-11-26)22-38-31(46)25-8-12-27(13-9-25)39-33-41-32(42-34(43-33)40-28-14-16-29(44)17-15-28)37-19-21-47-20-18-36-30(45)24-4-2-1-3-5-24/h1-17,44H,18-22H2,(H,36,45)(H,38,46)(H3,37,39,40,41,42,43)
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n/an/a 31.7n/an/an/an/an/an/a



Albert Einstein College of Medicine of Yeshiva University

US Patent


Assay Description
MDCK cells stably transfected with rat PGT (Endo et al., 2002) were seeded at 15-20% confluence on 24-well plates. The day on which the cells were se...


US Patent US8952150 (2015)

More data for this
Ligand-Target Pair
Prostaglandin transporter (PGT)


(Rattus norvegicus (Rat))
BDBM144814
PNG
(US8952150, 124)
Show SMILES CN(c1ccc(cc1)C(=O)NCc1ccccc1)c1nc(NCCOCCOCCNC(=O)c2ccccc2)nc(Nc2ccc(O)cc2)n1
Show InChI InChI=1S/C37H40N8O5/c1-45(31-16-12-29(13-17-31)34(48)40-26-27-8-4-2-5-9-27)37-43-35(42-36(44-37)41-30-14-18-32(46)19-15-30)39-21-23-50-25-24-49-22-20-38-33(47)28-10-6-3-7-11-28/h2-19,46H,20-26H2,1H3,(H,38,47)(H,40,48)(H2,39,41,42,43,44)
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n/an/a 34n/an/an/an/an/an/a



Albert Einstein College of Medicine of Yeshiva University

US Patent


Assay Description
MDCK cells stably transfected with rat PGT (Endo et al., 2002) were seeded at 15-20% confluence on 24-well plates. The day on which the cells were se...


US Patent US8952150 (2015)

More data for this
Ligand-Target Pair
Prostaglandin transporter (PGT)


(Rattus norvegicus (Rat))
BDBM144816
PNG
(US8952150, 137)
Show SMILES COc1ccc(cc1)C(=O)NCCOCCNc1nc(Nc2ccc(O)cc2)nc(Nc2ccc(cc2)C(=O)NCc2ccccc2)n1
Show InChI InChI=1S/C35H36N8O5/c1-47-30-17-9-26(10-18-30)31(45)36-19-21-48-22-20-37-33-41-34(43-35(42-33)40-28-13-15-29(44)16-14-28)39-27-11-7-25(8-12-27)32(46)38-23-24-5-3-2-4-6-24/h2-18,44H,19-23H2,1H3,(H,36,45)(H,38,46)(H3,37,39,40,41,42,43)
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n/an/a 36.7n/an/an/an/an/an/a



Albert Einstein College of Medicine of Yeshiva University

US Patent


Assay Description
MDCK cells stably transfected with rat PGT (Endo et al., 2002) were seeded at 15-20% confluence on 24-well plates. The day on which the cells were se...


US Patent US8952150 (2015)

More data for this
Ligand-Target Pair
Prostaglandin transporter (PGT)


(Rattus norvegicus (Rat))
BDBM144795
PNG
(US8952150, 22 | US8952150, 83)
Show SMILES Oc1ccc(Nc2nc(NCCOCCOCCNC(=O)c3ccccc3)nc(Nc3ccc(cc3)C(=O)NCc3ccccc3)n2)cc1
Show InChI InChI=1S/C36H38N8O5/c45-31-17-15-30(16-18-31)41-36-43-34(38-20-22-49-24-23-48-21-19-37-32(46)27-9-5-2-6-10-27)42-35(44-36)40-29-13-11-28(12-14-29)33(47)39-25-26-7-3-1-4-8-26/h1-18,45H,19-25H2,(H,37,46)(H,39,47)(H3,38,40,41,42,43,44)
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n/an/a 42.7n/an/an/an/an/an/a



Albert Einstein College of Medicine of Yeshiva University

US Patent


Assay Description
MDCK cells stably transfected with rat PGT (Endo et al., 2002) were seeded at 15-20% confluence on 24-well plates. The day on which the cells were se...


US Patent US8952150 (2015)

More data for this
Ligand-Target Pair
Prostaglandin transporter (PGT)


(Rattus norvegicus (Rat))
BDBM144818
PNG
(US8952150, 146)
Show SMILES OC(=O)c1cc(Nc2nc(NCCOCCOCCNC(=O)c3ccccc3)nc(Nc3ccc(cc3)C(=O)NCc3ccc(F)cc3)n2)ccc1O
Show InChI InChI=1S/C37H37FN8O7/c38-27-10-6-24(7-11-27)23-41-33(49)26-8-12-28(13-9-26)42-36-44-35(45-37(46-36)43-29-14-15-31(47)30(22-29)34(50)51)40-17-19-53-21-20-52-18-16-39-32(48)25-4-2-1-3-5-25/h1-15,22,47H,16-21,23H2,(H,39,48)(H,41,49)(H,50,51)(H3,40,42,43,44,45,46)
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n/an/a 44.8n/an/an/an/an/an/a



Albert Einstein College of Medicine of Yeshiva University

US Patent


Assay Description
MDCK cells stably transfected with rat PGT (Endo et al., 2002) were seeded at 15-20% confluence on 24-well plates. The day on which the cells were se...


US Patent US8952150 (2015)

More data for this
Ligand-Target Pair
Prostaglandin transporter (PGT)


(Rattus norvegicus (Rat))
BDBM144811
PNG
(US8952150, 105)
Show SMILES Oc1ccc(Nc2nc(NCCOCCOCCNC(=O)c3ccccc3)nc(Nc3ccc(cc3)C(=O)NCc3cccc(F)c3)n2)cc1
Show InChI InChI=1S/C36H37FN8O5/c37-28-8-4-5-25(23-28)24-40-33(48)27-9-11-29(12-10-27)41-35-43-34(44-36(45-35)42-30-13-15-31(46)16-14-30)39-18-20-50-22-21-49-19-17-38-32(47)26-6-2-1-3-7-26/h1-16,23,46H,17-22,24H2,(H,38,47)(H,40,48)(H3,39,41,42,43,44,45)
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n/an/a 47.5n/an/an/an/an/an/a



Albert Einstein College of Medicine of Yeshiva University

US Patent


Assay Description
MDCK cells stably transfected with rat PGT (Endo et al., 2002) were seeded at 15-20% confluence on 24-well plates. The day on which the cells were se...


US Patent US8952150 (2015)

More data for this
Ligand-Target Pair
Prostaglandin transporter (PGT)


(Rattus norvegicus (Rat))
BDBM144801
PNG
(US8952150, 64)
Show SMILES O=C(NCCOCCOCCNc1nc(Nc2ccc(cc2)C(=O)NCc2ccccc2)nc(Nc2ccc3[nH]ncc3c2)n1)c1ccccc1
Show InChI InChI=1S/C37H38N10O4/c48-33(27-9-5-2-6-10-27)38-17-19-50-21-22-51-20-18-39-35-44-36(46-37(45-35)43-31-15-16-32-29(23-31)25-41-47-32)42-30-13-11-28(12-14-30)34(49)40-24-26-7-3-1-4-8-26/h1-16,23,25H,17-22,24H2,(H,38,48)(H,40,49)(H,41,47)(H3,39,42,43,44,45,46)
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n/an/a 115n/an/an/an/an/an/a



Albert Einstein College of Medicine of Yeshiva University

US Patent


Assay Description
MDCK cells stably transfected with rat PGT (Endo et al., 2002) were seeded at 15-20% confluence on 24-well plates. The day on which the cells were se...


US Patent US8952150 (2015)

More data for this
Ligand-Target Pair
Prostaglandin transporter (PGT)


(Rattus norvegicus (Rat))
BDBM144790
PNG
(US8952150, 8 | US8952150, T26A)
Show SMILES Oc1ccc(Nc2nc(NCCOCCOCCNC(=O)c3ccccc3)nc(Nc3ccc(cc3)C(=O)NCCOCCOCCN=[N+]=[N-])n2)cc1
Show InChI InChI=1S/C35H43N11O7/c36-46-40-17-21-53-25-24-51-19-15-38-32(49)27-6-8-28(9-7-27)41-34-43-33(44-35(45-34)42-29-10-12-30(47)13-11-29)39-16-20-52-23-22-50-18-14-37-31(48)26-4-2-1-3-5-26/h1-13,47H,14-25H2,(H,37,48)(H,38,49)(H3,39,41,42,43,44,45)
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n/an/a 224n/an/an/an/an/an/a



Albert Einstein College of Medicine of Yeshiva University

US Patent


Assay Description
MDCK cells stably transfected with rat PGT (Endo et al., 2002) were seeded at 15-20% confluence on 24-well plates. The day on which the cells were se...


US Patent US8952150 (2015)

More data for this
Ligand-Target Pair
Prostaglandin transporter (PGT)


(Rattus norvegicus (Rat))
BDBM144790
PNG
(US8952150, 8 | US8952150, T26A)
Show SMILES Oc1ccc(Nc2nc(NCCOCCOCCNC(=O)c3ccccc3)nc(Nc3ccc(cc3)C(=O)NCCOCCOCCN=[N+]=[N-])n2)cc1
Show InChI InChI=1S/C35H43N11O7/c36-46-40-17-21-53-25-24-51-19-15-38-32(49)27-6-8-28(9-7-27)41-34-43-33(44-35(45-34)42-29-10-12-30(47)13-11-29)39-16-20-52-23-22-50-18-14-37-31(48)26-4-2-1-3-5-26/h1-13,47H,14-25H2,(H,37,48)(H,38,49)(H3,39,41,42,43,44,45)
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n/an/a 378n/an/an/an/an/an/a



Albert Einstein College of Medicine of Yeshiva University

US Patent


Assay Description
MDCK cells stably transfected with rat PGT (Endo et al., 2002) were seeded at 15-20% confluence on 24-well plates. The day on which the cells were se...


US Patent US8952150 (2015)

More data for this
Ligand-Target Pair
Prostaglandin transporter (PGT)


(Rattus norvegicus (Rat))
BDBM144795
PNG
(US8952150, 22 | US8952150, 83)
Show SMILES Oc1ccc(Nc2nc(NCCOCCOCCNC(=O)c3ccccc3)nc(Nc3ccc(cc3)C(=O)NCc3ccccc3)n2)cc1
Show InChI InChI=1S/C36H38N8O5/c45-31-17-15-30(16-18-31)41-36-43-34(38-20-22-49-24-23-48-21-19-37-32(46)27-9-5-2-6-10-27)42-35(44-36)40-29-13-11-28(12-14-29)33(47)39-25-26-7-3-1-4-8-26/h1-18,45H,19-25H2,(H,37,46)(H,39,47)(H3,38,40,41,42,43,44)
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n/an/a 609n/an/an/an/an/an/a



Albert Einstein College of Medicine of Yeshiva University

US Patent


Assay Description
MDCK cells stably transfected with rat PGT (Endo et al., 2002) were seeded at 15-20% confluence on 24-well plates. The day on which the cells were se...


US Patent US8952150 (2015)

More data for this
Ligand-Target Pair
Prostaglandin transporter (PGT)


(Rattus norvegicus (Rat))
BDBM144809
PNG
(US8952150, 91)
Show SMILES Oc1ccc(Nc2nc(NCCOCCOCCNC(=O)c3ccccc3)nc(Nc3ccc(cc3)C(=O)NCc3ccc(Cl)cc3)n2)cc1
Show InChI InChI=1S/C36H37ClN8O5/c37-28-10-6-25(7-11-28)24-40-33(48)27-8-12-29(13-9-27)41-35-43-34(44-36(45-35)42-30-14-16-31(46)17-15-30)39-19-21-50-23-22-49-20-18-38-32(47)26-4-2-1-3-5-26/h1-17,46H,18-24H2,(H,38,47)(H,40,48)(H3,39,41,42,43,44,45)
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n/an/a 620n/an/an/an/an/an/a



Albert Einstein College of Medicine of Yeshiva University

US Patent


Assay Description
MDCK cells stably transfected with rat PGT (Endo et al., 2002) were seeded at 15-20% confluence on 24-well plates. The day on which the cells were se...


US Patent US8952150 (2015)

More data for this
Ligand-Target Pair
Prostaglandin transporter (PGT)


(Rattus norvegicus (Rat))
BDBM144807
PNG
(US8952150, 87)
Show SMILES Oc1ccc(Nc2nc(NCCOCCOCCNC(=O)c3ccccc3)nc(Nc3ccc(cc3)C(=O)NCc3cccc(Cl)c3)n2)cc1
Show InChI InChI=1S/C36H37ClN8O5/c37-28-8-4-5-25(23-28)24-40-33(48)27-9-11-29(12-10-27)41-35-43-34(44-36(45-35)42-30-13-15-31(46)16-14-30)39-18-20-50-22-21-49-19-17-38-32(47)26-6-2-1-3-7-26/h1-16,23,46H,17-22,24H2,(H,38,47)(H,40,48)(H3,39,41,42,43,44,45)
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n/an/a 710n/an/an/an/an/an/a



Albert Einstein College of Medicine of Yeshiva University

US Patent


Assay Description
MDCK cells stably transfected with rat PGT (Endo et al., 2002) were seeded at 15-20% confluence on 24-well plates. The day on which the cells were se...


US Patent US8952150 (2015)

More data for this
Ligand-Target Pair
Prostaglandin transporter (PGT)


(Rattus norvegicus (Rat))
BDBM144797
PNG
(US8952150, 44)
Show SMILES CCCCCCNC(=O)c1ccc(Nc2nc(NCCOCCOCCNC(=O)c3ccccc3)nc(Nc3ccc(O)cc3)n2)cc1
Show InChI InChI=1S/C35H44N8O5/c1-2-3-4-8-19-36-32(46)27-11-13-28(14-12-27)39-34-41-33(42-35(43-34)40-29-15-17-30(44)18-16-29)38-21-23-48-25-24-47-22-20-37-31(45)26-9-6-5-7-10-26/h5-7,9-18,44H,2-4,8,19-25H2,1H3,(H,36,46)(H,37,45)(H3,38,39,40,41,42,43)
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n/an/a 760n/an/an/an/an/an/a



Albert Einstein College of Medicine of Yeshiva University

US Patent


Assay Description
MDCK cells stably transfected with rat PGT (Endo et al., 2002) were seeded at 15-20% confluence on 24-well plates. The day on which the cells were se...


US Patent US8952150 (2015)

More data for this
Ligand-Target Pair
Prostaglandin transporter (PGT)


(Rattus norvegicus (Rat))
BDBM144808
PNG
(US8952150, 88)
Show SMILES COc1cccc(CNC(=O)c2ccc(Nc3nc(NCCOCCOCCNC(=O)c4ccccc4)nc(Nc4ccc(O)cc4)n3)cc2)c1
Show InChI InChI=1S/C37H40N8O6/c1-49-32-9-5-6-26(24-32)25-40-34(48)28-10-12-29(13-11-28)41-36-43-35(44-37(45-36)42-30-14-16-31(46)17-15-30)39-19-21-51-23-22-50-20-18-38-33(47)27-7-3-2-4-8-27/h2-17,24,46H,18-23,25H2,1H3,(H,38,47)(H,40,48)(H3,39,41,42,43,44,45)
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n/an/a 820n/an/an/an/an/an/a



Albert Einstein College of Medicine of Yeshiva University

US Patent


Assay Description
MDCK cells stably transfected with rat PGT (Endo et al., 2002) were seeded at 15-20% confluence on 24-well plates. The day on which the cells were se...


US Patent US8952150 (2015)

More data for this
Ligand-Target Pair
Prostaglandin transporter (PGT)


(Rattus norvegicus (Rat))
BDBM144806
PNG
(US8952150, 86)
Show SMILES Oc1ccc(Nc2nc(NCCOCCOCCNC(=O)c3ccccc3)nc(Nc3ccc(cc3)C(=O)NCc3ccccc3-c3ccccc3)n2)cc1
Show InChI InChI=1S/C42H42N8O5/c51-36-21-19-35(20-22-36)47-42-49-40(44-24-26-55-28-27-54-25-23-43-38(52)31-11-5-2-6-12-31)48-41(50-42)46-34-17-15-32(16-18-34)39(53)45-29-33-13-7-8-14-37(33)30-9-3-1-4-10-30/h1-22,51H,23-29H2,(H,43,52)(H,45,53)(H3,44,46,47,48,49,50)
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n/an/a 870n/an/an/an/an/an/a



Albert Einstein College of Medicine of Yeshiva University

US Patent


Assay Description
MDCK cells stably transfected with rat PGT (Endo et al., 2002) were seeded at 15-20% confluence on 24-well plates. The day on which the cells were se...


US Patent US8952150 (2015)

More data for this
Ligand-Target Pair
Prostaglandin transporter (PGT)


(Rattus norvegicus (Rat))
BDBM144803
PNG
(US8952150, 69)
Show SMILES Oc1ccc(Nc2nc(NCCOCCOCCNC(=O)c3ccccc3)nc(Nc3ccc(cc3)C(=O)OCc3ccccc3)n2)cc1
Show InChI InChI=1S/C36H37N7O6/c44-31-17-15-30(16-18-31)40-36-42-34(38-20-22-48-24-23-47-21-19-37-32(45)27-9-5-2-6-10-27)41-35(43-36)39-29-13-11-28(12-14-29)33(46)49-25-26-7-3-1-4-8-26/h1-18,44H,19-25H2,(H,37,45)(H3,38,39,40,41,42,43)
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n/an/a 890n/an/an/an/an/an/a



Albert Einstein College of Medicine of Yeshiva University

US Patent


Assay Description
MDCK cells stably transfected with rat PGT (Endo et al., 2002) were seeded at 15-20% confluence on 24-well plates. The day on which the cells were se...


US Patent US8952150 (2015)

More data for this
Ligand-Target Pair
Prostaglandin transporter (PGT)


(Rattus norvegicus (Rat))
BDBM144804
PNG
(US8952150, 70)
Show SMILES Oc1ccc(Nc2nc(NCCOCCOCCNC(=O)c3ccccc3)nc(Nc3ccc(cc3)C(=O)NCc3ccccn3)n2)cc1
Show InChI InChI=1S/C35H37N9O5/c45-30-15-13-28(14-16-30)41-35-43-33(38-19-21-49-23-22-48-20-18-37-31(46)25-6-2-1-3-7-25)42-34(44-35)40-27-11-9-26(10-12-27)32(47)39-24-29-8-4-5-17-36-29/h1-17,45H,18-24H2,(H,37,46)(H,39,47)(H3,38,40,41,42,43,44)
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n/an/a 1.05E+3n/an/an/an/an/an/a



Albert Einstein College of Medicine of Yeshiva University

US Patent


Assay Description
MDCK cells stably transfected with rat PGT (Endo et al., 2002) were seeded at 15-20% confluence on 24-well plates. The day on which the cells were se...


US Patent US8952150 (2015)

More data for this
Ligand-Target Pair
Prostaglandin transporter (PGT)


(Rattus norvegicus (Rat))
BDBM144796
PNG
(US8952150, 43)
Show SMILES COC(=O)CCCCCCNC(=O)c1ccc(Nc2nc(NCCOCCOCCNC(=O)c3ccccc3)nc(Nc3ccc(O)cc3)n2)cc1
Show InChI InChI=1S/C37H46N8O7/c1-50-32(47)11-7-2-3-8-20-38-34(49)28-12-14-29(15-13-28)41-36-43-35(44-37(45-36)42-30-16-18-31(46)19-17-30)40-22-24-52-26-25-51-23-21-39-33(48)27-9-5-4-6-10-27/h4-6,9-10,12-19,46H,2-3,7-8,11,20-26H2,1H3,(H,38,49)(H,39,48)(H3,40,41,42,43,44,45)
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n/an/a 1.30E+3n/an/an/an/an/an/a



Albert Einstein College of Medicine of Yeshiva University

US Patent


Assay Description
MDCK cells stably transfected with rat PGT (Endo et al., 2002) were seeded at 15-20% confluence on 24-well plates. The day on which the cells were se...


US Patent US8952150 (2015)

More data for this
Ligand-Target Pair
Prostaglandin transporter (PGT)


(Rattus norvegicus (Rat))
BDBM144802
PNG
(US8952150, 65)
Show SMILES CCCCCCNC(=O)c1ccc(Nc2nc(NCCOCCOCCNC(=O)c3ccccc3)nc(Nc3ccc4[nH]ncc4c3)n2)cc1
Show InChI InChI=1S/C36H44N10O4/c1-2-3-4-8-17-37-33(48)27-11-13-29(14-12-27)41-35-43-34(44-36(45-35)42-30-15-16-31-28(24-30)25-40-46-31)39-19-21-50-23-22-49-20-18-38-32(47)26-9-6-5-7-10-26/h5-7,9-16,24-25H,2-4,8,17-23H2,1H3,(H,37,48)(H,38,47)(H,40,46)(H3,39,41,42,43,44,45)
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n/an/a 1.38E+3n/an/an/an/an/an/a



Albert Einstein College of Medicine of Yeshiva University

US Patent


Assay Description
MDCK cells stably transfected with rat PGT (Endo et al., 2002) were seeded at 15-20% confluence on 24-well plates. The day on which the cells were se...


US Patent US8952150 (2015)

More data for this
Ligand-Target Pair
Prostaglandin transporter (PGT)


(Rattus norvegicus (Rat))
BDBM144800
PNG
(US8952150, 59)
Show SMILES Oc1ccc(Nc2nc(NCCOCCNC(=O)c3ccccc3)nc(Nc3ccccc3)n2)cc1
Show InChI InChI=1S/C26H27N7O3/c34-22-13-11-21(12-14-22)30-26-32-24(31-25(33-26)29-20-9-5-2-6-10-20)28-16-18-36-17-15-27-23(35)19-7-3-1-4-8-19/h1-14,34H,15-18H2,(H,27,35)(H3,28,29,30,31,32,33)
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n/an/a 2.46E+3n/an/an/an/an/an/a



Albert Einstein College of Medicine of Yeshiva University

US Patent


Assay Description
MDCK cells stably transfected with rat PGT (Endo et al., 2002) were seeded at 15-20% confluence on 24-well plates. The day on which the cells were se...


US Patent US8952150 (2015)

More data for this
Ligand-Target Pair
Prostaglandin transporter (PGT)


(Rattus norvegicus (Rat))
BDBM144798
PNG
(US8952150, 53)
Show SMILES O=C(NCCOCCOCCNc1nc(Nc2ccccc2)nc(Nc2ccc3cn[nH]c3c2)n1)c1ccccc1
Show InChI InChI=1S/C29H31N9O3/c39-26(21-7-3-1-4-8-21)30-13-15-40-17-18-41-16-14-31-27-35-28(33-23-9-5-2-6-10-23)37-29(36-27)34-24-12-11-22-20-32-38-25(22)19-24/h1-12,19-20H,13-18H2,(H,30,39)(H,32,38)(H3,31,33,34,35,36,37)
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n/an/a 4.04E+3n/an/an/an/an/an/a



Albert Einstein College of Medicine of Yeshiva University

US Patent


Assay Description
MDCK cells stably transfected with rat PGT (Endo et al., 2002) were seeded at 15-20% confluence on 24-well plates. The day on which the cells were se...


US Patent US8952150 (2015)

More data for this
Ligand-Target Pair
Prostaglandin transporter (PGT)


(Rattus norvegicus (Rat))
BDBM144791
PNG
(US8952150, 4)
Show SMILES Oc1ccc(Nc2nc(NCCOCCOCCNC(=O)c3ccccc3)nc(Nc3ccccc3)n2)cc1
Show InChI InChI=1S/C28H31N7O4/c36-24-13-11-23(12-14-24)32-28-34-26(33-27(35-28)31-22-9-5-2-6-10-22)30-16-18-39-20-19-38-17-15-29-25(37)21-7-3-1-4-8-21/h1-14,36H,15-20H2,(H,29,37)(H3,30,31,32,33,34,35)
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n/an/a 4.85E+3n/an/an/an/an/an/a



Albert Einstein College of Medicine of Yeshiva University

US Patent


Assay Description
MDCK cells stably transfected with rat PGT (Endo et al., 2002) were seeded at 15-20% confluence on 24-well plates. The day on which the cells were se...


US Patent US8952150 (2015)

More data for this
Ligand-Target Pair
Prostaglandin transporter (PGT)


(Rattus norvegicus (Rat))
BDBM144799
PNG
(US8952150, 57)
Show SMILES OC(=O)Cc1ccc(Nc2nc(NCCOCCOCCNC(=O)c3ccccc3)nc(Nc3ccccc3)n2)cc1
Show InChI InChI=1S/C30H33N7O5/c38-26(39)21-22-11-13-25(14-12-22)34-30-36-28(35-29(37-30)33-24-9-5-2-6-10-24)32-16-18-42-20-19-41-17-15-31-27(40)23-7-3-1-4-8-23/h1-14H,15-21H2,(H,31,40)(H,38,39)(H3,32,33,34,35,36,37)
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US Patent
n/an/a 5.57E+3n/an/an/an/an/an/a



Albert Einstein College of Medicine of Yeshiva University

US Patent


Assay Description
MDCK cells stably transfected with rat PGT (Endo et al., 2002) were seeded at 15-20% confluence on 24-well plates. The day on which the cells were se...


US Patent US8952150 (2015)

More data for this
Ligand-Target Pair
Prostaglandin transporter (PGT)


(Rattus norvegicus (Rat))
BDBM144794
PNG
(US8952150, 17)
Show SMILES COC(=O)c1ccc(Nc2nc(NCCOCCOCCNC(=O)c3ccccc3)nc(Nc3ccc(O)cc3)n2)cc1
Show InChI InChI=1S/C30H33N7O6/c1-41-27(40)22-7-9-23(10-8-22)33-29-35-28(36-30(37-29)34-24-11-13-25(38)14-12-24)32-16-18-43-20-19-42-17-15-31-26(39)21-5-3-2-4-6-21/h2-14,38H,15-20H2,1H3,(H,31,39)(H3,32,33,34,35,36,37)
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n/an/a 6.57E+3n/an/an/an/an/an/a



Albert Einstein College of Medicine of Yeshiva University

US Patent


Assay Description
MDCK cells stably transfected with rat PGT (Endo et al., 2002) were seeded at 15-20% confluence on 24-well plates. The day on which the cells were se...


US Patent US8952150 (2015)

More data for this
Ligand-Target Pair
Prostaglandin transporter (PGT)


(Rattus norvegicus (Rat))
BDBM144793
PNG
(US8952150, 16)
Show SMILES CC(C)(C)NC(=O)c1ccc(Nc2nc(NCCOCCOCCNC(=O)c3ccccc3)nc(Nc3ccc(O)cc3)n2)cc1
Show InChI InChI=1S/C33H40N8O5/c1-33(2,3)41-29(44)24-9-11-25(12-10-24)36-31-38-30(39-32(40-31)37-26-13-15-27(42)16-14-26)35-18-20-46-22-21-45-19-17-34-28(43)23-7-5-4-6-8-23/h4-16,42H,17-22H2,1-3H3,(H,34,43)(H,41,44)(H3,35,36,37,38,39,40)
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n/an/a 9.77E+3n/an/an/an/an/an/a



Albert Einstein College of Medicine of Yeshiva University

US Patent


Assay Description
MDCK cells stably transfected with rat PGT (Endo et al., 2002) were seeded at 15-20% confluence on 24-well plates. The day on which the cells were se...


US Patent US8952150 (2015)

More data for this
Ligand-Target Pair