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Compile Data Set for Download or QSAR

Found 5 hits Enz. Inhib. hit(s) with Target = 'Protein kinase C epsilon' AND taxid = 10090   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Protein kinase C epsilon


(Mus musculus)
BDBM50269146
PNG
((R)-1,3,6,8-tetrahydroxy-2-(1-hydroxyethyl)anthrac...)
Show SMILES C[C@@H](O)c1c(O)cc2C(=O)c3cc(O)cc(O)c3C(=O)c2c1O
Show InChI InChI=1S/C16H12O7/c1-5(17)11-10(20)4-8-13(15(11)22)16(23)12-7(14(8)21)2-6(18)3-9(12)19/h2-5,17-20,22H,1H3/t5-/m1/s1
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n/an/a 1.85E+4n/an/an/an/an/an/a



Heinrich-Heine-Universität

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant PKCepsilon expressed in Sf9 insect cells


J Nat Prod 63: 739-45 (2000)

More data for this
Ligand-Target Pair
Protein kinase C epsilon


(Mus musculus)
BDBM50269147
PNG
((R)-1,3,6,8-tetrahydroxy-2-(1-methoxyethyl)anthrac...)
Show SMILES CO[C@H](C)c1c(O)cc2C(=O)c3cc(O)cc(O)c3C(=O)c2c1O
Show InChI InChI=1S/C17H14O7/c1-6(24-2)12-11(20)5-9-14(16(12)22)17(23)13-8(15(9)21)3-7(18)4-10(13)19/h3-6,18-20,22H,1-2H3/t6-/m1/s1
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n/an/a 2.70E+4n/an/an/an/an/an/a



Heinrich-Heine-Universität

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant PKCepsilon expressed in Sf9 insect cells


J Nat Prod 63: 739-45 (2000)

More data for this
Ligand-Target Pair
Protein kinase C epsilon


(Mus musculus)
BDBM50269144
PNG
(10-hydroxy-18-methoxybetaenone | CHEMBL498247)
Show SMILES CCC(C)[C@H]1[C@](C)(O)C(=O)[C@@]2(O)C[C@](C)(O)C[C@@H](C)[C@@H]2[C@]1(C)C(=O)\C=C\OC
Show InChI InChI=1S/C22H36O6/c1-8-13(2)16-20(5,15(23)9-10-28-7)17-14(3)11-19(4,25)12-22(17,27)18(24)21(16,6)26/h9-10,13-14,16-17,25-27H,8,11-12H2,1-7H3/b10-9+/t13?,14-,16-,17-,19-,20-,21+,22-/m1/s1
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n/an/a 3.60E+4n/an/an/an/an/an/a



Heinrich-Heine-Universität

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant PKCepsilon expressed in Sf9 insect cells


J Nat Prod 63: 739-45 (2000)

More data for this
Ligand-Target Pair
Protein kinase C epsilon


(Mus musculus)
BDBM50269148
PNG
((R)-1,2,3,6,8-pentahydroxy-7-(1-methoxyethyl)anthr...)
Show SMILES CO[C@H](C)c1c(O)cc2C(=O)c3cc(O)c(O)c(O)c3C(=O)c2c1O
Show InChI InChI=1S/C17H14O8/c1-5(25-2)10-8(18)3-6-11(15(10)22)16(23)12-7(13(6)20)4-9(19)14(21)17(12)24/h3-5,18-19,21-22,24H,1-2H3/t5-/m1/s1
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n/an/a 5.40E+4n/an/an/an/an/an/a



Heinrich-Heine-Universität

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant PKCepsilon expressed in Sf9 insect cells


J Nat Prod 63: 739-45 (2000)

More data for this
Ligand-Target Pair
Protein kinase C epsilon


(Mus musculus)
BDBM50269145
PNG
(10-hydroxy-18-N-2-naphthyl-N-phenylaminobetaenone ...)
Show SMILES CCC(C)[C@H]1[C@](C)(O)C(=O)[C@@]2(O)C[C@](C)(O)C[C@@H](C)[C@@H]2[C@]1(C)C(=O)\C=C\N(c1ccccc1)c1ccc2ccccc2c1
Show InChI InChI=1S/C37H45NO5/c1-7-24(2)31-35(5,32-25(3)22-34(4,41)23-37(32,43)33(40)36(31,6)42)30(39)19-20-38(28-15-9-8-10-16-28)29-18-17-26-13-11-12-14-27(26)21-29/h8-21,24-25,31-32,41-43H,7,22-23H2,1-6H3/b20-19+/t24?,25-,31-,32-,34-,35-,36+,37-/m1/s1
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n/an/a>1.00E+5n/an/an/an/an/an/a



Heinrich-Heine-Universität

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant PKCepsilon expressed in Sf9 insect cells


J Nat Prod 63: 739-45 (2000)

More data for this
Ligand-Target Pair