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Found 3 hits Enz. Inhib. hit(s) with Target = 'Protein-glutamine gamma-glutamyltransferase 2' AND taxid = 10090   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Protein-glutamine gamma-glutamyltransferase 2


(Mus musculus)
BDBM50420459
PNG
(CHEMBL2086528)
Show SMILES C=CC(=O)Nc1ccc(cc1)S(=O)(=O)N1CCN(CC1)C(=O)C12CC3CC(CC(C3)C1)C2
Show InChI InChI=1S/C24H31N3O4S/c1-2-22(28)25-20-3-5-21(6-4-20)32(30,31)27-9-7-26(8-10-27)23(29)24-14-17-11-18(15-24)13-19(12-17)16-24/h2-6,17-19H,1,7-16H2,(H,25,28)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 16n/an/an/an/an/an/a



Evotec (UK) Ltd.

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant TG2 by fluorescent transamidation assay


Citation and Details
More data for this
Ligand-Target Pair
Protein-glutamine gamma-glutamyltransferase 2


(Mus musculus)
BDBM50392906
PNG
(CHEMBL2152204)
Show SMILES COc1ccc(CCNC(=O)c2ccc(cc2)S(=O)(=O)N2CCC(CC2)NC(=O)C=C)cc1
Show InChI InChI=1S/C24H29N3O5S/c1-3-23(28)26-20-13-16-27(17-14-20)33(30,31)22-10-6-19(7-11-22)24(29)25-15-12-18-4-8-21(32-2)9-5-18/h3-11,20H,1,12-17H2,2H3,(H,25,29)(H,26,28)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
n/an/a 55n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of mouse TGM2


Citation and Details
More data for this
Ligand-Target Pair
Protein-glutamine gamma-glutamyltransferase 2


(Mus musculus)
BDBM50400619
PNG
(CHEMBL2203476)
Show SMILES CC(C)(C)OC(=O)CNC(=O)[C@H](CCCCNC(=O)C=C)NC(=O)OCc1ccccc1
Show InChI InChI=1S/C23H33N3O6/c1-5-19(27)24-14-10-9-13-18(21(29)25-15-20(28)32-23(2,3)4)26-22(30)31-16-17-11-7-6-8-12-17/h5-8,11-12,18H,1,9-10,13-16H2,2-4H3,(H,24,27)(H,25,29)(H,26,30)/t18-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
n/an/a 6.20E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of mouse transglutaminase 2


Citation and Details
More data for this
Ligand-Target Pair