BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 11 hits Enz. Inhib. hit(s) with Target = 'Proteinase-activated receptor 4' AND taxid = 9606   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Proteinase-activated receptor 4


(Homo sapiens)
BDBM50024253
PNG
(CHEMBL3334887)
Show SMILES CCOC(=O)c1ccc(cc1)-c1cn(Cc2ccccc2)c2ccccc12
Show InChI InChI=1S/C24H21NO2/c1-2-27-24(26)20-14-12-19(13-15-20)22-17-25(16-18-8-4-3-5-9-18)23-11-7-6-10-21(22)23/h3-15,17H,2,16H2,1H3
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 66n/an/an/an/an/an/a



Northwest Agriculture& Forestry University

Curated by ChEMBL


Assay Description
Antagonist activity at PAR4 in PAR-4-AP-stimulated human platelets compound pretreated for 5 mins by fluorescent PAC1 integrin alpha2bb3 activation a...


Citation and Details
More data for this
Ligand-Target Pair
Proteinase-activated receptor 4


(Homo sapiens)
BDBM50024254
PNG
(CHEMBL125021)
Show SMILES CCOC(=O)c1ccc(cc1)-c1nn(Cc2ccccc2)c2ccccc12
Show InChI InChI=1S/C23H20N2O2/c1-2-27-23(26)19-14-12-18(13-15-19)22-20-10-6-7-11-21(20)25(24-22)16-17-8-4-3-5-9-17/h3-15H,2,16H2,1H3
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 130n/an/an/an/an/an/a



Northwest Agriculture& Forestry University

Curated by ChEMBL


Assay Description
Antagonist activity at PAR4 in PAR-4-AP-stimulated human platelets compound pretreated for 5 mins by fluorescent PAC1 integrin alpha2bb3 activation a...


Citation and Details
More data for this
Ligand-Target Pair
Proteinase-activated receptor 4


(Homo sapiens)
BDBM50024252
PNG
(CHEMBL1609104)
Show SMILES Cn1c(CO)c(-c2ccccc2)c2cc(ccc12)[N+]([O-])=O
Show InChI InChI=1S/C16H14N2O3/c1-17-14-8-7-12(18(20)21)9-13(14)16(15(17)10-19)11-5-3-2-4-6-11/h2-9,19H,10H2,1H3
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 140n/an/an/an/an/an/a



Northwest Agriculture& Forestry University

Curated by ChEMBL


Assay Description
Antagonist activity at PAR4 in PAR-4-AP-stimulated human platelets compound pretreated for 5 mins by fluorescent PAC1 integrin alpha2bb3 activation a...


Citation and Details
More data for this
Ligand-Target Pair
Proteinase-activated receptor 4


(Homo sapiens)
BDBM50024255
PNG
(CHEMBL3334944)
Show SMILES CCCNCc1c(-c2ccccc2)c2cc(ccc2n1C)[N+]([O-])=O
Show InChI InChI=1S/C19H21N3O2/c1-3-11-20-13-18-19(14-7-5-4-6-8-14)16-12-15(22(23)24)9-10-17(16)21(18)2/h4-10,12,20H,3,11,13H2,1-2H3
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 279n/an/an/an/an/an/a



Northwest Agriculture& Forestry University

Curated by ChEMBL


Assay Description
Antagonist activity at PAR4 in PAR-4-AP-stimulated human platelets compound pretreated for 5 mins by fluorescent PAC1 integrin alpha2bb3 activation a...


Citation and Details
More data for this
Ligand-Target Pair
Proteinase-activated receptor 4


(Homo sapiens)
BDBM50024258
PNG
(CHEMBL3334941)
Show SMILES Cn1c(COCc2ccccc2)c(-c2ccccc2)c2cc(ccc12)[N+]([O-])=O
Show InChI InChI=1S/C23H20N2O3/c1-24-21-13-12-19(25(26)27)14-20(21)23(18-10-6-3-7-11-18)22(24)16-28-15-17-8-4-2-5-9-17/h2-14H,15-16H2,1H3
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 336n/an/an/an/an/an/a



Northwest Agriculture& Forestry University

Curated by ChEMBL


Assay Description
Antagonist activity at PAR4 in PAR-4-AP-stimulated human platelets compound pretreated for 5 mins by fluorescent PAC1 integrin alpha2bb3 activation a...


Citation and Details
More data for this
Ligand-Target Pair
Proteinase-activated receptor 4


(Homo sapiens)
BDBM50024259
PNG
(CHEMBL3334940)
Show SMILES CCCOCc1c(-c2ccccc2)c2cc(ccc2n1C)[N+]([O-])=O
Show InChI InChI=1S/C19H20N2O3/c1-3-11-24-13-18-19(14-7-5-4-6-8-14)16-12-15(21(22)23)9-10-17(16)20(18)2/h4-10,12H,3,11,13H2,1-2H3
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 646n/an/an/an/an/an/a



Northwest Agriculture& Forestry University

Curated by ChEMBL


Assay Description
Antagonist activity at PAR4 in PAR-4-AP-stimulated human platelets compound pretreated for 5 mins by fluorescent PAC1 integrin alpha2bb3 activation a...


Citation and Details
More data for this
Ligand-Target Pair
Proteinase-activated receptor 4


(Homo sapiens)
BDBM50024260
PNG
(CHEMBL3334939)
Show SMILES COCc1c(-c2ccccc2)c2cc(ccc2n1C)[N+]([O-])=O
Show InChI InChI=1S/C17H16N2O3/c1-18-15-9-8-13(19(20)21)10-14(15)17(16(18)11-22-2)12-6-4-3-5-7-12/h3-10H,11H2,1-2H3
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 785n/an/an/an/an/an/a



Northwest Agriculture& Forestry University

Curated by ChEMBL


Assay Description
Antagonist activity at PAR4 in PAR-4-AP-stimulated human platelets compound pretreated for 5 mins by fluorescent PAC1 integrin alpha2bb3 activation a...


Citation and Details
More data for this
Ligand-Target Pair
Proteinase-activated receptor 4


(Homo sapiens)
BDBM50024257
PNG
(CHEMBL3334942)
Show SMILES CNCc1c(-c2ccccc2)c2cc(ccc2n1C)[N+]([O-])=O
Show InChI InChI=1S/C17H17N3O2/c1-18-11-16-17(12-6-4-3-5-7-12)14-10-13(20(21)22)8-9-15(14)19(16)2/h3-10,18H,11H2,1-2H3
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 793n/an/an/an/an/an/a



Northwest Agriculture& Forestry University

Curated by ChEMBL


Assay Description
Antagonist activity at PAR4 in PAR-4-AP-stimulated human platelets compound pretreated for 5 mins by fluorescent PAC1 integrin alpha2bb3 activation a...


Citation and Details
More data for this
Ligand-Target Pair
Proteinase-activated receptor 4


(Homo sapiens)
BDBM50024256
PNG
(CHEMBL3334943)
Show SMILES COCCOCc1c(-c2ccccc2)c2cc(ccc2n1C)[N+]([O-])=O
Show InChI InChI=1S/C19H20N2O4/c1-20-17-9-8-15(21(22)23)12-16(17)19(14-6-4-3-5-7-14)18(20)13-25-11-10-24-2/h3-9,12H,10-11,13H2,1-2H3
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 5.13E+3n/an/an/an/an/an/a



Northwest Agriculture& Forestry University

Curated by ChEMBL


Assay Description
Antagonist activity at PAR4 in PAR-4-AP-stimulated human platelets compound pretreated for 5 mins by fluorescent PAC1 integrin alpha2bb3 activation a...


Citation and Details
More data for this
Ligand-Target Pair
Proteinase-activated receptor 4


(Homo sapiens)
BDBM50024261
PNG
(CHEMBL3334901)
Show SMILES COc1ccc(cn1)-c1c(CO)n(C)c2ccc(cc12)C#N
Show InChI InChI=1S/C17H15N3O2/c1-20-14-5-3-11(8-18)7-13(14)17(15(20)10-21)12-4-6-16(22-2)19-9-12/h3-7,9,21H,10H2,1-2H3
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Northwest Agriculture& Forestry University

Curated by ChEMBL


Assay Description
Antagonist activity at PAR4 in PAR-4-AP-stimulated human platelets compound pretreated for 5 mins by fluorescent PAC1 integrin alpha2bb3 activation a...


Citation and Details
More data for this
Ligand-Target Pair
Proteinase-activated receptor 4


(Homo sapiens)
BDBM50024262
PNG
(CHEMBL3334933)
Show SMILES COc1ccc(cn1)-c1c(CO)n(Cc2cccc(OC(F)(F)F)c2)c2ncccc12
Show InChI InChI=1S/C22H18F3N3O3/c1-30-19-8-7-15(11-27-19)20-17-6-3-9-26-21(17)28(18(20)13-29)12-14-4-2-5-16(10-14)31-22(23,24)25/h2-11,29H,12-13H2,1H3
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
Article
PubMed
n/an/a 1.00E+4n/an/an/an/an/an/a



Northwest Agriculture& Forestry University

Curated by ChEMBL


Assay Description
Antagonist activity at PAR4 in PAR-4-AP-stimulated human platelets compound pretreated for 5 mins by fluorescent PAC1 integrin alpha2bb3 activation a...


Citation and Details
More data for this
Ligand-Target Pair