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Compile Data Set for Download or QSAR

Found 50 hits Enz. Inhib. hit(s) with Target = 'Proton-coupled amino acid transporter 1' AND taxid = 9606   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Proton-coupled amino acid transporter 1


(Homo sapiens)
BDBM50357224
PNG
(D-PROLINE)
Show SMILES OC(=O)[C@H]1CCCN1
Show InChI InChI=1S/C5H9NO2/c7-5(8)4-2-1-3-6-4/h4,6H,1-3H2,(H,7,8)/t4-/m1/s1
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PubMed
1.20E+6n/an/an/an/an/an/an/an/a



Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL


Assay Description
Inhibition of human PAT1-mediated L-[3H]proline uptake in human Caco2 cells after 10 mins by liquid scintillation counting


Citation and Details
Checked by Author
More data for this
Ligand-Target Pair
Proton-coupled amino acid transporter 1


(Homo sapiens)
BDBM50021610
PNG
(3-Guanidino-propionic acid | CHEMBL20489 | Guanidi...)
Show SMILES NC(=N)NCCC(O)=O
Show InChI InChI=1S/C4H9N3O2/c5-4(6)7-2-1-3(8)9/h1-2H2,(H,8,9)(H4,5,6,7)
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1.30E+6n/an/an/an/an/an/an/an/a



Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL


Assay Description
Inhibition of human PAT1-mediated L-[3H]proline uptake in human Caco2 cells after 10 mins by liquid scintillation counting


Citation and Details
Checked by Author
More data for this
Ligand-Target Pair
Proton-coupled amino acid transporter 1


(Homo sapiens)
BDBM50021601
PNG
((carbamimidamido)acetic acid | CHEMBL281593 | Glyc...)
Show SMILES NC(=N)NCC(O)=O
Show InChI InChI=1S/C3H7N3O2/c4-3(5)6-1-2(7)8/h1H2,(H,7,8)(H4,4,5,6)
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1.50E+6n/an/an/an/an/an/an/an/a



Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL


Assay Description
Inhibition of human PAT1-mediated L-[3H]proline uptake in human Caco2 cells after 10 mins by liquid scintillation counting


Citation and Details
Checked by Author
More data for this
Ligand-Target Pair
Proton-coupled amino acid transporter 1


(Homo sapiens)
BDBM50000100
PNG
((-)-(S)-proline | (-)-2-pyrrolidinecarboxylic acid...)
Show SMILES OC(=O)[C@@H]1CCCN1
Show InChI InChI=1S/C5H9NO2/c7-5(8)4-2-1-3-6-4/h4,6H,1-3H2,(H,7,8)/t4-/m0/s1
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1.60E+6n/an/an/an/an/an/an/an/a



Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL


Assay Description
Inhibition of human PAT1-mediated L-[3H]proline uptake in human Caco2 cells after 10 mins by liquid scintillation counting


Citation and Details
Checked by Author
More data for this
Ligand-Target Pair
Proton-coupled amino acid transporter 1


(Homo sapiens)
BDBM50357225
PNG
(CHEMBL1165239)
Show SMILES OC(=O)[C@@H]1CCN1
Show InChI InChI=1S/C4H7NO2/c6-4(7)3-1-2-5-3/h3,5H,1-2H2,(H,6,7)/t3-/m0/s1
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1.80E+6n/an/an/an/an/an/an/an/a



Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL


Assay Description
Inhibition of human PAT1-mediated L-[3H]proline uptake in human Caco2 cells after 10 mins by liquid scintillation counting


Citation and Details
Checked by Author
More data for this
Ligand-Target Pair
Proton-coupled amino acid transporter 1


(Homo sapiens)
BDBM50357226
PNG
(BETAINE)
Show SMILES C[N+](C)(C)CC(O)=O
Show InChI InChI=1S/C5H11NO2/c1-6(2,3)4-5(7)8/h4H2,1-3H3/p+1
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1.90E+6n/an/an/an/an/an/an/an/a



Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL


Assay Description
Inhibition of human PAT1-mediated L-[3H]proline uptake in human Caco2 cells after 10 mins by liquid scintillation counting


Citation and Details
Checked by Author
More data for this
Ligand-Target Pair
Proton-coupled amino acid transporter 1


(Homo sapiens)
BDBM50017225
PNG
((methylamino)acetic acid | (methylamino)ethanoic a...)
Show SMILES CNCC(O)=O
Show InChI InChI=1S/C3H7NO2/c1-4-2-3(5)6/h4H,2H2,1H3,(H,5,6)
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1.90E+6n/an/an/an/an/an/an/an/a



Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL


Assay Description
Inhibition of human PAT1-mediated L-[3H]proline uptake in human Caco2 cells after 10 mins by liquid scintillation counting


Citation and Details
Checked by Author
More data for this
Ligand-Target Pair
Proton-coupled amino acid transporter 1


(Homo sapiens)
BDBM50357227
PNG
(CHEMBL1234201)
Show SMILES CN[C@@H](C)C(O)=O
Show InChI InChI=1S/C4H9NO2/c1-3(5-2)4(6)7/h3,5H,1-2H3,(H,6,7)/t3-/m0/s1
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2.20E+6n/an/an/an/an/an/an/an/a



Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL


Assay Description
Inhibition of human PAT1-mediated L-[3H]proline uptake in human Caco2 cells after 10 mins by liquid scintillation counting


Citation and Details
Checked by Author
More data for this
Ligand-Target Pair
Proton-coupled amino acid transporter 1


(Homo sapiens)
BDBM50357217
PNG
(CHEMBL1916079)
Show SMILES CNC(C)(C)C(O)=O
Show InChI InChI=1S/C5H11NO2/c1-5(2,6-3)4(7)8/h6H,1-3H3,(H,7,8)
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2.20E+6n/an/an/an/an/an/an/an/a



Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL


Assay Description
Inhibition of human PAT1-mediated L-[3H]proline uptake in human Caco2 cells after 10 mins by liquid scintillation counting


Citation and Details
Checked by Author
More data for this
Ligand-Target Pair
Proton-coupled amino acid transporter 1


(Homo sapiens)
BDBM50000106
PNG
(4-CARBOXYPIPERIDINE | CHEMBL279998 | Piperidine-4-...)
Show SMILES OC(=O)C1CCNCC1
Show InChI InChI=1S/C6H11NO2/c8-6(9)5-1-3-7-4-2-5/h5,7H,1-4H2,(H,8,9)
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2.30E+6n/an/an/an/an/an/an/an/a



Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL


Assay Description
Inhibition of human PAT1-mediated L-[3H]proline uptake in human Caco2 cells after 10 mins by liquid scintillation counting


Citation and Details
Checked by Author
More data for this
Ligand-Target Pair
Proton-coupled amino acid transporter 1


(Homo sapiens)
BDBM50000102
PNG
(3-aminopropanoic acidbeta-alanine | Alanine-beta |...)
Show SMILES NCCC(O)=O
Show InChI InChI=1S/C3H7NO2/c4-2-1-3(5)6/h1-2,4H2,(H,5,6)
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2.40E+6n/an/an/an/an/an/an/an/a



Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL


Assay Description
Inhibition of human PAT1-mediated L-[3H]proline uptake in human Caco2 cells after 10 mins by liquid scintillation counting


Citation and Details
Checked by Author
More data for this
Ligand-Target Pair
Proton-coupled amino acid transporter 1


(Homo sapiens)
BDBM50357228
PNG
(CHEMBL1231898)
Show SMILES OC(=O)[C@H]1CCCCN1
Show InChI InChI=1S/C6H11NO2/c8-6(9)5-3-1-2-4-7-5/h5,7H,1-4H2,(H,8,9)/t5-/m1/s1
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2.50E+6n/an/an/an/an/an/an/an/a



Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL


Assay Description
Inhibition of human PAT1-mediated L-[3H]proline uptake in human Caco2 cells after 10 mins by liquid scintillation counting


Citation and Details
Checked by Author
More data for this
Ligand-Target Pair
Proton-coupled amino acid transporter 1


(Homo sapiens)
BDBM50357218
PNG
(CHEMBL1311694)
Show SMILES OC(=O)[C@H]1NC[C@H]2C[C@@H]12
Show InChI InChI=1S/C6H9NO2/c8-6(9)5-4-1-3(4)2-7-5/h3-5,7H,1-2H2,(H,8,9)/t3-,4-,5+/m1/s1
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2.70E+6n/an/an/an/an/an/an/an/a



Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL


Assay Description
Inhibition of human PAT1-mediated L-[3H]proline uptake in human Caco2 cells after 10 mins by liquid scintillation counting


Citation and Details
Checked by Author
More data for this
Ligand-Target Pair
Proton-coupled amino acid transporter 1


(Homo sapiens)
BDBM50000099
PNG
((2S)-2-aminopropanoic acid | (S)-2-aminopropanoic ...)
Show SMILES C[C@H](N)C(O)=O
Show InChI InChI=1S/C3H7NO2/c1-2(4)3(5)6/h2H,4H2,1H3,(H,5,6)/t2-/m0/s1
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2.80E+6n/an/an/an/an/an/an/an/a



Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL


Assay Description
Inhibition of human PAT1-mediated L-[3H]proline uptake in human Caco2 cells after 10 mins by liquid scintillation counting


Citation and Details
Checked by Author
More data for this
Ligand-Target Pair
Proton-coupled amino acid transporter 1


(Homo sapiens)
BDBM50357229
PNG
(CREATINE)
Show SMILES CN(CC(O)=O)C(N)=N
Show InChI InChI=1S/C4H9N3O2/c1-7(4(5)6)2-3(8)9/h2H2,1H3,(H3,5,6)(H,8,9)
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3.20E+6n/an/an/an/an/an/an/an/a



Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL


Assay Description
Inhibition of human PAT1-mediated L-[3H]proline uptake in human Caco2 cells after 10 mins by liquid scintillation counting


Citation and Details
Checked by Author
More data for this
Ligand-Target Pair
Proton-coupled amino acid transporter 1


(Homo sapiens)
BDBM50357230
PNG
(CHEMBL1229563)
Show SMILES O[C@H]1CN[C@H](C1)C(O)=O
Show InChI InChI=1S/C5H9NO3/c7-3-1-4(5(8)9)6-2-3/h3-4,6-7H,1-2H2,(H,8,9)/t3-,4-/m1/s1
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3.30E+6n/an/an/an/an/an/an/an/a



Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL


Assay Description
Inhibition of human PAT1-mediated L-[3H]proline uptake in human Caco2 cells after 10 mins by liquid scintillation counting


Citation and Details
Checked by Author
More data for this
Ligand-Target Pair
Proton-coupled amino acid transporter 1


(Homo sapiens)
BDBM24183
PNG
(4-amino-n-[2,3-3H]butyric acid | 4-aminobutanoic a...)
Show SMILES NCCCC(O)=O
Show InChI InChI=1S/C4H9NO2/c5-3-1-2-4(6)7/h1-3,5H2,(H,6,7)
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4.00E+6n/an/an/an/an/an/an/an/a



Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL


Assay Description
Inhibition of human PAT1-mediated L-[3H]proline uptake in human Caco2 cells after 10 mins by liquid scintillation counting


Citation and Details
Checked by Author
More data for this
Ligand-Target Pair
Proton-coupled amino acid transporter 1


(Homo sapiens)
BDBM50038178
PNG
((+)-4-Amino-3-isoxazolidinone | (4R)-4-aminoisoxaz...)
Show SMILES N[C@@H]1CON=C1O
Show InChI InChI=1S/C3H6N2O2/c4-2-1-7-5-3(2)6/h2H,1,4H2,(H,5,6)/t2-/m1/s1
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4.40E+6n/an/an/an/an/an/an/an/a



Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL


Assay Description
Inhibition of human PAT1-mediated L-[3H]proline uptake in human Caco2 cells after 10 mins by liquid scintillation counting


Citation and Details
Checked by Author
More data for this
Ligand-Target Pair
Proton-coupled amino acid transporter 1


(Homo sapiens)
BDBM50357219
PNG
(CHEMBL1361446 | VIGABATRIN)
Show SMILES N[C@H](CCC(O)=O)C=C
Show InChI InChI=1S/C6H11NO2/c1-2-5(7)3-4-6(8)9/h2,5H,1,3-4,7H2,(H,8,9)/t5-/m0/s1
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4.80E+6n/an/an/an/an/an/an/an/a



Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL


Assay Description
Inhibition of human PAT1-mediated L-[3H]proline uptake in human Caco2 cells after 10 mins by liquid scintillation counting


Citation and Details
Checked by Author
More data for this
Ligand-Target Pair
Proton-coupled amino acid transporter 1


(Homo sapiens)
BDBM18133
PNG
(2-aminoacetic acid | CHEMBL773 | Glycine | [14C]Gl...)
Show SMILES NCC(O)=O
Show InChI InChI=1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)
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5.10E+6n/an/an/an/an/an/an/an/a



Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL


Assay Description
Inhibition of human PAT1-mediated L-[3H]proline uptake in human Caco2 cells after 10 mins by liquid scintillation counting


Citation and Details
Checked by Author
More data for this
Ligand-Target Pair
Proton-coupled amino acid transporter 1


(Homo sapiens)
BDBM50032955
PNG
(1,2,3,6-Tetrahydro-pyridine-4-carboxylic acid | 1,...)
Show SMILES OC(=O)C1=CCNCC1
Show InChI InChI=1S/C6H9NO2/c8-6(9)5-1-3-7-4-2-5/h1,7H,2-4H2,(H,8,9)
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5.80E+6n/an/an/an/an/an/an/an/a



Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL


Assay Description
Inhibition of human PAT1-mediated L-[3H]proline uptake in human Caco2 cells after 10 mins by liquid scintillation counting


Citation and Details
Checked by Author
More data for this
Ligand-Target Pair
Proton-coupled amino acid transporter 1


(Homo sapiens)
BDBM50281573
PNG
(3-Amino-propane-1-sulfonic acid | 3-ammoniopropane...)
Show SMILES NCCCS(O)(=O)=O
Show InChI InChI=1S/C3H9NO3S/c4-2-1-3-8(5,6)7/h1-4H2,(H,5,6,7)
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7.10E+6n/an/an/an/an/an/an/an/a



Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL


Assay Description
Inhibition of human PAT1-mediated L-[3H]proline uptake in human Caco2 cells after 10 mins by liquid scintillation counting


Citation and Details
Checked by Author
More data for this
Ligand-Target Pair
Proton-coupled amino acid transporter 1


(Homo sapiens)
BDBM50357231
PNG
(L-CYCLOSERINE)
Show SMILES N[C@H]1CON=C1O
Show InChI InChI=1S/C3H6N2O2/c4-2-1-7-5-3(2)6/h2H,1,4H2,(H,5,6)/t2-/m0/s1
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7.40E+6n/an/an/an/an/an/an/an/a



Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL


Assay Description
Inhibition of human PAT1-mediated L-[3H]proline uptake in human Caco2 cells after 10 mins by liquid scintillation counting


Citation and Details
Checked by Author
More data for this
Ligand-Target Pair
Proton-coupled amino acid transporter 1


(Homo sapiens)
BDBM50357220
PNG
(TAURINE)
Show SMILES NCCS(O)(=O)=O
Show InChI InChI=1S/C2H7NO3S/c3-1-2-7(4,5)6/h1-3H2,(H,4,5,6)
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7.80E+6n/an/an/an/an/an/an/an/a



Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL


Assay Description
Inhibition of human PAT1-mediated L-[3H]proline uptake in human Caco2 cells after 10 mins by liquid scintillation counting


Citation and Details
Checked by Author
More data for this
Ligand-Target Pair
Proton-coupled amino acid transporter 1


(Homo sapiens)
BDBM50357232
PNG
(THIOPROLINE)
Show SMILES OC(=O)[C@@H]1CSCN1
Show InChI InChI=1S/C4H7NO2S/c6-4(7)3-1-8-2-5-3/h3,5H,1-2H2,(H,6,7)/t3-/m0/s1
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7.90E+6n/an/an/an/an/an/an/an/a



Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL


Assay Description
Inhibition of human PAT1-mediated L-[3H]proline uptake in human Caco2 cells after 10 mins by liquid scintillation counting


Citation and Details
Checked by Author
More data for this
Ligand-Target Pair
Proton-coupled amino acid transporter 1


(Homo sapiens)
BDBM50357233
PNG
(CHEMBL352418)
Show SMILES O[C@H]1CN[C@@H](C1)C(O)=O
Show InChI InChI=1S/C5H9NO3/c7-3-1-4(5(8)9)6-2-3/h3-4,6-7H,1-2H2,(H,8,9)/t3-,4+/m1/s1
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9.00E+6n/an/an/an/an/an/an/an/a



Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL


Assay Description
Inhibition of human PAT1-mediated L-[3H]proline uptake in human Caco2 cells after 10 mins by liquid scintillation counting


Citation and Details
Checked by Author
More data for this
Ligand-Target Pair
Proton-coupled amino acid transporter 1


(Homo sapiens)
BDBM50052429
PNG
((2S)-piperidine-2-carboxylate | (S)-pipecolate | L...)
Show SMILES [O-]C(=O)[C@@H]1CCCCN1
Show InChI InChI=1S/C6H11NO2/c8-6(9)5-3-1-2-4-7-5/h5,7H,1-4H2,(H,8,9)/p-1/t5-/m0/s1
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1.10E+7n/an/an/an/an/an/an/an/a



Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL


Assay Description
Inhibition of human PAT1-mediated L-[3H]proline uptake in human Caco2 cells after 10 mins by liquid scintillation counting


Citation and Details
Checked by Author
More data for this
Ligand-Target Pair
Proton-coupled amino acid transporter 1


(Homo sapiens)
BDBM50226518
PNG
(3-Aminobenzoesaeure | 3-aminobenzoic acid | CHEMBL...)
Show SMILES Nc1cccc(c1)C(O)=O
Show InChI InChI=1S/C7H7NO2/c8-6-3-1-2-5(4-6)7(9)10/h1-4H,8H2,(H,9,10)
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1.20E+7n/an/an/an/an/an/an/an/a



Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL


Assay Description
Inhibition of human PAT1-mediated L-[3H]proline uptake in human Caco2 cells after 10 mins by liquid scintillation counting


Citation and Details
Checked by Author
More data for this
Ligand-Target Pair
Proton-coupled amino acid transporter 1


(Homo sapiens)
BDBM50357208
PNG
(CREATININE)
Show SMILES Cn1cc(O)nc1N
Show InChI InChI=1S/C4H7N3O/c1-7-2-3(8)6-4(7)5/h2,8H,1H3,(H2,5,6)
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1.50E+7n/an/an/an/an/an/an/an/a



Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL


Assay Description
Inhibition of human PAT1-mediated L-[3H]proline uptake in human Caco2 cells after 10 mins by liquid scintillation counting


Citation and Details
Checked by Author
More data for this
Ligand-Target Pair
Proton-coupled amino acid transporter 1


(Homo sapiens)
BDBM50000407
PNG
(2-carboxypyridine | CHEMBL72628 | alpha-picolinic ...)
Show SMILES OC(=O)c1ccccn1
Show InChI InChI=1S/C6H5NO2/c8-6(9)5-3-1-2-4-7-5/h1-4H,(H,8,9)
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1.80E+7n/an/an/an/an/an/an/an/a



Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL


Assay Description
Inhibition of human PAT1-mediated L-[3H]proline uptake in human Caco2 cells after 10 mins by liquid scintillation counting


Citation and Details
Checked by Author
More data for this
Ligand-Target Pair
Proton-coupled amino acid transporter 1


(Homo sapiens)
BDBM50000109
PNG
((2R)-2-aminopropanoic acid | (R)-2-aminopropanoic ...)
Show SMILES C[C@@H](N)C(O)=O
Show InChI InChI=1S/C3H7NO2/c1-2(4)3(5)6/h2H,4H2,1H3,(H,5,6)/t2-/m1/s1
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1.90E+7n/an/an/an/an/an/an/an/a



Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL


Assay Description
Inhibition of human PAT1-mediated L-[3H]proline uptake in human Caco2 cells after 10 mins by liquid scintillation counting


Citation and Details
Checked by Author
More data for this
Ligand-Target Pair
Proton-coupled amino acid transporter 1


(Homo sapiens)
BDBM23167
PNG
((2R)-2-amino-3-hydroxypropanoic acid | CHEMBL28512...)
Show SMILES N[C@H](CO)C(O)=O
Show InChI InChI=1S/C3H7NO3/c4-2(1-5)3(6)7/h2,5H,1,4H2,(H,6,7)/t2-/m1/s1
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2.20E+7n/an/an/an/an/an/an/an/a



Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL


Assay Description
Inhibition of human PAT1-mediated L-[3H]proline uptake in human Caco2 cells after 10 mins by liquid scintillation counting


Citation and Details
Checked by Author
More data for this
Ligand-Target Pair
Proton-coupled amino acid transporter 1


(Homo sapiens)
BDBM36629
PNG
(Aminoisobutyric (AIB))
Show SMILES CC(C)([NH3+])C([O-])=O
Show InChI InChI=1S/C4H9NO2/c1-4(2,5)3(6)7/h5H2,1-2H3,(H,6,7)
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2.30E+7n/an/an/an/an/an/an/an/a



Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL


Assay Description
Inhibition of human PAT1-mediated L-[3H]proline uptake in human Caco2 cells after 10 mins by liquid scintillation counting


Citation and Details
Checked by Author
More data for this
Ligand-Target Pair
Proton-coupled amino acid transporter 1


(Homo sapiens)
BDBM50357209
PNG
(CHEMBL1233477)
Show SMILES O[C@@H]1CN[C@@H](C1)C(O)=O
Show InChI InChI=1S/C5H9NO3/c7-3-1-4(5(8)9)6-2-3/h3-4,6-7H,1-2H2,(H,8,9)/t3-,4-/m0/s1
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3.00E+7n/an/an/an/an/an/an/an/a



Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL


Assay Description
Inhibition of human PAT1-mediated L-[3H]proline uptake in human Caco2 cells after 10 mins by liquid scintillation counting


Citation and Details
Checked by Author
More data for this
Ligand-Target Pair
Proton-coupled amino acid transporter 1


(Homo sapiens)
BDBM50357210
PNG
(CHEMBL1230782)
Show SMILES CC[C@H](N)C(O)=O
Show InChI InChI=1S/C4H9NO2/c1-2-3(5)4(6)7/h3H,2,5H2,1H3,(H,6,7)/t3-/m0/s1
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3.50E+7n/an/an/an/an/an/an/an/a



Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL


Assay Description
Inhibition of human PAT1-mediated L-[3H]proline uptake in human Caco2 cells after 10 mins by liquid scintillation counting


Citation and Details
Checked by Author
More data for this
Ligand-Target Pair
Proton-coupled amino acid transporter 1


(Homo sapiens)
BDBM50357211
PNG
(177 J.D. | AMINOCAPROIC ACID | Amicar | Aminocapro...)
Show SMILES NCCCCCC(O)=O
Show InChI InChI=1S/C6H13NO2/c7-5-3-1-2-4-6(8)9/h1-5,7H2,(H,8,9)
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3.50E+7n/an/an/an/an/an/an/an/a



Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL


Assay Description
Inhibition of human PAT1-mediated L-[3H]proline uptake in human Caco2 cells after 10 mins by liquid scintillation counting


Citation and Details
Checked by Author
More data for this
Ligand-Target Pair
Proton-coupled amino acid transporter 1


(Homo sapiens)
BDBM50357212
PNG
((L)-SERINE | Serine)
Show SMILES N[C@@H](CO)C(O)=O
Show InChI InChI=1S/C3H7NO3/c4-2(1-5)3(6)7/h2,5H,1,4H2,(H,6,7)/t2-/m0/s1
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3.50E+7n/an/an/an/an/an/an/an/a



Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL


Assay Description
Inhibition of human PAT1-mediated L-[3H]proline uptake in human Caco2 cells after 10 mins by liquid scintillation counting


Citation and Details
Checked by Author
More data for this
Ligand-Target Pair
Proton-coupled amino acid transporter 1


(Homo sapiens)
BDBM18140
PNG
((2S,3S)-2-amino-3-methylpentanoic acid | Isoleucin...)
Show SMILES CC[C@H](C)[C@H](N)C(O)=O
Show InChI InChI=1S/C6H13NO2/c1-3-4(2)5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)/t4-,5-/m0/s1
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3.70E+7n/an/an/an/an/an/an/an/a



Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL


Assay Description
Inhibition of human PAT1-mediated L-[3H]proline uptake in human Caco2 cells after 10 mins by liquid scintillation counting


Citation and Details
Checked by Author
More data for this
Ligand-Target Pair
Proton-coupled amino acid transporter 1


(Homo sapiens)
BDBM50357213
PNG
(CHEMBL1233466)
Show SMILES O[C@H]1CCN[C@@H]1C(O)=O
Show InChI InChI=1S/C5H9NO3/c7-3-1-2-6-4(3)5(8)9/h3-4,6-7H,1-2H2,(H,8,9)/t3-,4-/m0/s1
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3.70E+7n/an/an/an/an/an/an/an/a



Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL


Assay Description
Inhibition of human PAT1-mediated L-[3H]proline uptake in human Caco2 cells after 10 mins by liquid scintillation counting


Citation and Details
Checked by Author
More data for this
Ligand-Target Pair
Proton-coupled amino acid transporter 1


(Homo sapiens)
BDBM50026437
PNG
(CHEMBL22830 | azolidine | pyrrolidine | tetrahydro...)
Show SMILES C1CCNC1
Show InChI InChI=1S/C4H9N/c1-2-4-5-3-1/h5H,1-4H2
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3.80E+7n/an/an/an/an/an/an/an/a



Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL


Assay Description
Inhibition of human PAT1-mediated L-[3H]proline uptake in human Caco2 cells after 10 mins by liquid scintillation counting


Citation and Details
Checked by Author
More data for this
Ligand-Target Pair
Proton-coupled amino acid transporter 1


(Homo sapiens)
BDBM50357214
PNG
(CHEMBL1916078)
Show SMILES C1CSCN1
Show InChI InChI=1S/C3H7NS/c1-2-5-3-4-1/h4H,1-3H2
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4.40E+7n/an/an/an/an/an/an/an/a



Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL


Assay Description
Inhibition of human PAT1-mediated L-[3H]proline uptake in human Caco2 cells after 10 mins by liquid scintillation counting


Citation and Details
Checked by Author
More data for this
Ligand-Target Pair
Proton-coupled amino acid transporter 1


(Homo sapiens)
BDBM50357215
PNG
(NORVALINE)
Show SMILES CCC[C@H](N)C(O)=O
Show InChI InChI=1S/C5H11NO2/c1-2-3-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)/t4-/m0/s1
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4.60E+7n/an/an/an/an/an/an/an/a



Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL


Assay Description
Inhibition of human PAT1-mediated L-[3H]proline uptake in human Caco2 cells after 10 mins by liquid scintillation counting


Citation and Details
Checked by Author
More data for this
Ligand-Target Pair
Proton-coupled amino acid transporter 1


(Homo sapiens)
BDBM50109609
PNG
((2R)-2-amino-3-mercaptopropanoic acid | (2R)-2-ami...)
Show SMILES N[C@@H](CS)C(O)=O
Show InChI InChI=1S/C3H7NO2S/c4-2(1-7)3(5)6/h2,7H,1,4H2,(H,5,6)/t2-/m0/s1
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4.60E+7n/an/an/an/an/an/an/an/a



Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL


Assay Description
Inhibition of human PAT1-mediated L-[3H]proline uptake in human Caco2 cells after 10 mins by liquid scintillation counting


Citation and Details
Checked by Author
More data for this
Ligand-Target Pair
Proton-coupled amino acid transporter 1


(Homo sapiens)
BDBM50357221
PNG
(CHEMBL442218)
Show SMILES OC(=O)[C@@H]1CSC(=O)N1
Show InChI InChI=1S/C4H5NO3S/c6-3(7)2-1-9-4(8)5-2/h2H,1H2,(H,5,8)(H,6,7)/t2-/m0/s1
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4.60E+7n/an/an/an/an/an/an/an/a



Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL


Assay Description
Inhibition of human PAT1-mediated L-[3H]proline uptake in human Caco2 cells after 10 mins by liquid scintillation counting


Citation and Details
Checked by Author
More data for this
Ligand-Target Pair
Proton-coupled amino acid transporter 1


(Homo sapiens)
BDBM50357222
PNG
(CHEMBL1916080)
Show SMILES OC[C@@H]1CCCN1
Show InChI InChI=1S/C5H11NO/c7-4-5-2-1-3-6-5/h5-7H,1-4H2/t5-/m0/s1
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5.00E+7n/an/an/an/an/an/an/an/a



Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL


Assay Description
Inhibition of human PAT1-mediated L-[3H]proline uptake in human Caco2 cells after 10 mins by liquid scintillation counting


Citation and Details
Checked by Author
More data for this
Ligand-Target Pair
Proton-coupled amino acid transporter 1


(Homo sapiens)
BDBM50026449
PNG
(CHEMBL15487 | pip | piperidine)
Show SMILES C1CCNCC1
Show InChI InChI=1S/C5H11N/c1-2-4-6-5-3-1/h6H,1-5H2
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5.40E+7n/an/an/an/an/an/an/an/a



Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL


Assay Description
Inhibition of human PAT1-mediated L-[3H]proline uptake in human Caco2 cells after 10 mins by liquid scintillation counting


Citation and Details
Checked by Author
More data for this
Ligand-Target Pair
Proton-coupled amino acid transporter 1


(Homo sapiens)
BDBM50023575
PNG
(4-hydroxy-butyric acid | 4-hydroxybutanoic acid | ...)
Show SMILES OCCCC(O)=O
Show InChI InChI=1S/C4H8O3/c5-3-1-2-4(6)7/h5H,1-3H2,(H,6,7)
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6.50E+7n/an/an/an/an/an/an/an/a



Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL


Assay Description
Inhibition of human PAT1-mediated L-[3H]proline uptake in human Caco2 cells after 10 mins by liquid scintillation counting


Citation and Details
Checked by Author
More data for this
Ligand-Target Pair
Proton-coupled amino acid transporter 1


(Homo sapiens)
BDBM50357223
PNG
(CHEMBL1916081)
Show SMILES CCC[C@@H](N)C(O)=O
Show InChI InChI=1S/C5H11NO2/c1-2-3-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)/t4-/m1/s1
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1.00E+8n/an/an/an/an/an/an/an/a



Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL


Assay Description
Inhibition of human PAT1-mediated L-[3H]proline uptake in human Caco2 cells after 10 mins by liquid scintillation counting


Citation and Details
Checked by Author
More data for this
Ligand-Target Pair
Proton-coupled amino acid transporter 1


(Homo sapiens)
BDBM50219348
PNG
((2S)-2-amino-4-methylpentanoic acid | (S)-(+)-leuc...)
Show SMILES CC(C)C[C@H](N)C(O)=O
Show InChI InChI=1S/C6H13NO2/c1-4(2)3-5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)/t5-/m0/s1
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1.00E+8n/an/an/an/an/an/an/an/a



Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL


Assay Description
Inhibition of human PAT1-mediated L-[3H]proline uptake in human Caco2 cells after 10 mins by liquid scintillation counting


Citation and Details
Checked by Author
More data for this
Ligand-Target Pair
Proton-coupled amino acid transporter 1


(Homo sapiens)
BDBM50357216
PNG
(CHEMBL1232398)
Show SMILES CC(C)[C@@H](N)C(O)=O
Show InChI InChI=1S/C5H11NO2/c1-3(2)4(6)5(7)8/h3-4H,6H2,1-2H3,(H,7,8)/t4-/m1/s1
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Article
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1.00E+8n/an/an/an/an/an/an/an/a



Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL


Assay Description
Inhibition of human PAT1-mediated L-[3H]proline uptake in human Caco2 cells after 10 mins by liquid scintillation counting


Citation and Details
Checked by Author
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Ligand-Target Pair