BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 5 hits Enz. Inhib. hit(s) with Target = 'Puromycin-sensitive aminopeptidase' AND taxid = 9606   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Puromycin-sensitive aminopeptidase


(Homo sapiens)
BDBM50121712
PNG
(ANTAQ | CHEMBL169736)
Show SMILES O=c1[nH]c2ccccc2c(=O)n1-c1c2ccccc2cc2ccccc12
Show InChI InChI=1S/C22H14N2O2/c25-21-18-11-5-6-12-19(18)23-22(26)24(21)20-16-9-3-1-7-14(16)13-15-8-2-4-10-17(15)20/h1-13H,(H,23,26)
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 2.90E+3n/an/an/an/an/an/a



The University of Tokyo

Curated by ChEMBL


Assay Description
Puromycin sensitive aminopeptidase inhibitory activity of the compound was determined by the use of L-Ala AMC with MOLT-4


Bioorg Med Chem Lett 13: 83-6 (2002)

More data for this
Ligand-Target Pair
Puromycin-sensitive aminopeptidase


(Homo sapiens)
BDBM50121708
PNG
(CHEMBL168510 | MPAQ-22)
Show SMILES CCc1cccc(CC)c1-n1c(=O)n(C)c2ccccc2c1=O
Show InChI InChI=1S/C19H20N2O2/c1-4-13-9-8-10-14(5-2)17(13)21-18(22)15-11-6-7-12-16(15)20(3)19(21)23/h6-12H,4-5H2,1-3H3
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 3.40E+3n/an/an/an/an/an/a



The University of Tokyo

Curated by ChEMBL


Assay Description
Puromycin sensitive aminopeptidase inhibitory activity of the compound was determined by the use of L-Ala AMC with MOLT-4


Bioorg Med Chem Lett 13: 83-6 (2002)

More data for this
Ligand-Target Pair
Puromycin-sensitive aminopeptidase


(Homo sapiens)
BDBM50121709
PNG
(CHEMBL169458 | PAQ-22)
Show SMILES CCc1cccc(CC)c1-n1c(=O)[nH]c2ccccc2c1=O
Show InChI InChI=1S/C18H18N2O2/c1-3-12-8-7-9-13(4-2)16(12)20-17(21)14-10-5-6-11-15(14)19-18(20)22/h5-11H,3-4H2,1-2H3,(H,19,22)
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
PubMed
n/an/a 3.80E+3n/an/an/an/an/an/a



The University of Tokyo

Curated by ChEMBL


Assay Description
Puromycin sensitive aminopeptidase inhibitory activity of the compound was determined by the use of L-Ala AMC with MOLT-4


Bioorg Med Chem Lett 13: 83-6 (2002)

More data for this
Ligand-Target Pair
Puromycin-sensitive aminopeptidase


(Homo sapiens)
BDBM50121711
PNG
(CHEMBL169895 | DAMPAQ)
Show SMILES CCc1cc(NS(=O)(=O)c2ccc3c(cccc3c2)N(C)C)cc(CC)c1-n1c(=O)n(C)c2ccccc2c1=O
Show InChI InChI=1S/C31H32N4O4S/c1-6-20-17-23(32-40(38,39)24-15-16-25-22(19-24)11-10-14-27(25)33(3)4)18-21(7-2)29(20)35-30(36)26-12-8-9-13-28(26)34(5)31(35)37/h8-19,32H,6-7H2,1-5H3
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
AffyNet 
PubMed
n/an/a 4.60E+3n/an/an/an/an/an/a



The University of Tokyo

Curated by ChEMBL


Assay Description
Puromycin sensitive aminopeptidase inhibitory activity of the compound was determined by the use of L-Ala AMC with MOLT-4


Bioorg Med Chem Lett 13: 83-6 (2002)

More data for this
Ligand-Target Pair
Puromycin-sensitive aminopeptidase


(Homo sapiens)
BDBM50121710
PNG
(2-(2,6-Diethyl-phenyl)-4H-isoquinoline-1,3-dione |...)
Show SMILES CCc1cccc(CC)c1-n1c(O)cc2ccccc2c1=O
Show InChI InChI=1S/C19H19NO2/c1-3-13-9-7-10-14(4-2)18(13)20-17(21)12-15-8-5-6-11-16(15)19(20)22/h5-12,21H,3-4H2,1-2H3
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
PubMed
n/an/a 7.80E+3n/an/an/an/an/an/a



The University of Tokyo

Curated by ChEMBL


Assay Description
Puromycin sensitive aminopeptidase inhibitory activity of the compound was determined by the use of L-Ala AMC with MOLT-4


Bioorg Med Chem Lett 13: 83-6 (2002)

More data for this
Ligand-Target Pair