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Compile Data Set for Download or QSAR

Found 5 hits Enz. Inhib. hit(s) with Target = 'Regulatory protein E2' AND taxid = 10583   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Regulatory protein E2


(Human papillomavirus type 1a)
BDBM50127140
PNG
((-)-etoposide | (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-d...)
Show SMILES COc1cc(cc(OC)c1O)[C@H]1[C@@H]2[C@H](COC2=O)[C@H](O[C@@H]2O[C@@H]3CO[C@@H](C)O[C@H]3[C@H](O)[C@H]2O)c2cc3OCOc3cc12
Show InChI InChI=1S/C29H32O13/c1-11-36-9-20-27(40-11)24(31)25(32)29(41-20)42-26-14-7-17-16(38-10-39-17)6-13(14)21(22-15(26)8-37-28(22)33)12-4-18(34-2)23(30)19(5-12)35-3/h4-7,11,15,20-22,24-27,29-32H,8-10H2,1-3H3/t11-,15+,20-,21-,22+,24-,25-,26-,27-,29+/m1/s1
UniProtKB/SwissProt

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KEGG
MMDB
PC cid
PC sid
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Article
PubMed
n/an/an/a 2.10E+5n/an/an/an/an/a



Tokyo University of Science

Curated by ChEMBL


Assay Description
Binding affinity to HPV1a recombinant E2 protein by surface plasmon resonance method


Citation and Details
More data for this
Ligand-Target Pair
Regulatory protein E2


(Human papillomavirus type 1a)
BDBM50035218
PNG
(CHEMBL61 | PODOFILOX | Podophyllinic acid lactone ...)
Show SMILES COc1cc(cc(OC)c1OC)[C@H]1[C@@H]2[C@H](COC2=O)[C@@H](O)c2cc3OCOc3cc12
Show InChI InChI=1S/C22H22O8/c1-25-16-4-10(5-17(26-2)21(16)27-3)18-11-6-14-15(30-9-29-14)7-12(11)20(23)13-8-28-22(24)19(13)18/h4-7,13,18-20,23H,8-9H2,1-3H3/t13-,18+,19-,20-/m0/s1
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KEGG
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Article
PubMed
n/an/an/a 2.41E+4n/an/an/an/an/a



Tokyo University of Science

Curated by ChEMBL


Assay Description
Binding affinity to HPV1a recombinant E2 protein by surface plasmon resonance method


Citation and Details
More data for this
Ligand-Target Pair
Regulatory protein E2


(Human papillomavirus type 1a)
BDBM50035218
PNG
(CHEMBL61 | PODOFILOX | Podophyllinic acid lactone ...)
Show SMILES COc1cc(cc(OC)c1OC)[C@H]1[C@@H]2[C@H](COC2=O)[C@@H](O)c2cc3OCOc3cc12
Show InChI InChI=1S/C22H22O8/c1-25-16-4-10(5-17(26-2)21(16)27-3)18-11-6-14-15(30-9-29-14)7-12(11)20(23)13-8-28-22(24)19(13)18/h4-7,13,18-20,23H,8-9H2,1-3H3/t13-,18+,19-,20-/m0/s1
UniProtKB/SwissProt

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CHEMBL
KEGG
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PC sid
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Article
PubMed
n/an/an/a>4.00E+5n/an/an/an/an/a



Tokyo University of Science

Curated by ChEMBL


Assay Description
Binding affinity to HPV1a recombinant E2 protein DNA binding domain by surface plasmon resonance assay


Citation and Details
More data for this
Ligand-Target Pair
Regulatory protein E2


(Human papillomavirus type 1a)
BDBM50035218
PNG
(CHEMBL61 | PODOFILOX | Podophyllinic acid lactone ...)
Show SMILES COc1cc(cc(OC)c1OC)[C@H]1[C@@H]2[C@H](COC2=O)[C@@H](O)c2cc3OCOc3cc12
Show InChI InChI=1S/C22H22O8/c1-25-16-4-10(5-17(26-2)21(16)27-3)18-11-6-14-15(30-9-29-14)7-12(11)20(23)13-8-28-22(24)19(13)18/h4-7,13,18-20,23H,8-9H2,1-3H3/t13-,18+,19-,20-/m0/s1
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CHEMBL
KEGG
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PC sid
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Article
PubMed
n/an/an/a 1.05E+3n/an/an/an/an/a



Tokyo University of Science

Curated by ChEMBL


Assay Description
Binding affinity to HPV1a recombinant E2 protein hinge domain by surface plasmon resonance assay


Citation and Details
More data for this
Ligand-Target Pair
Regulatory protein E2


(Human papillomavirus type 1a)
BDBM50035218
PNG
(CHEMBL61 | PODOFILOX | Podophyllinic acid lactone ...)
Show SMILES COc1cc(cc(OC)c1OC)[C@H]1[C@@H]2[C@H](COC2=O)[C@@H](O)c2cc3OCOc3cc12
Show InChI InChI=1S/C22H22O8/c1-25-16-4-10(5-17(26-2)21(16)27-3)18-11-6-14-15(30-9-29-14)7-12(11)20(23)13-8-28-22(24)19(13)18/h4-7,13,18-20,23H,8-9H2,1-3H3/t13-,18+,19-,20-/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
KEGG
PC cid
PC sid
PDB
UniChem

Patents


Similars

AffyNet 
Article
PubMed
n/an/an/a>4.00E+5n/an/an/an/an/a



Tokyo University of Science

Curated by ChEMBL


Assay Description
Binding affinity to HPV1a recombinant E2 protein activator domain by surface plasmon resonance assay


Citation and Details
More data for this
Ligand-Target Pair