BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Retinoic Acid Receptors Gamma / Alpha' AND taxid = 9606   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Retinoic Acid Receptors Gamma / Alpha


(Homo sapiens (Human))
BDBM36810
PNG
(BMS753)
Show SMILES CC1(C)C(=O)C(C)(C)c2cc(ccc12)C(=O)Nc1ccc(cc1)C(O)=O
Show InChI InChI=1S/C21H21NO4/c1-20(2)15-10-7-13(11-16(15)21(3,4)19(20)26)17(23)22-14-8-5-12(6-9-14)18(24)25/h5-11H,1-4H3,(H,22,23)(H,24,25)
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
Article
PubMed
1 -47.8n/an/an/an/an/a8.04



Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC)



Assay Description
Competitive assay were perform with 5nM tritiated all-trans retinoic acid (t-RA; 5nM) with or without 100-fold excess of non-radioactive t-RA (500nM)...


Citation and Details
More data for this
Ligand-Target Pair
Retinoic Acid Receptors Gamma / Alpha


(Homo sapiens (Human))
BDBM36811
PNG
(BMS614)
Show SMILES CC1(C)CC=C(c2cnc3ccccc3c2)c2cc(ccc12)C(=O)Nc1ccc(cc1)C(O)=O
Show InChI InChI=1S/C29H24N2O3/c1-29(2)14-13-23(21-15-19-5-3-4-6-26(19)30-17-21)24-16-20(9-12-25(24)29)27(32)31-22-10-7-18(8-11-22)28(33)34/h3-13,15-17H,14H2,1-2H3,(H,31,32)(H,33,34)
GoogleScholar
AffyNet 
Purchase

MMDB
PC cid
PC sid
UniChem

Patents

AffyNet 
Article
PubMed
1 -47.8n/an/an/an/an/a8.04



Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC)



Assay Description
Competitive assay were perform with 5nM tritiated all-trans retinoic acid (t-RA; 5nM) with or without 100-fold excess of non-radioactive t-RA (500nM)...


Citation and Details
More data for this
Ligand-Target Pair