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Compile Data Set for Download or QSAR

Found 550 hits Enz. Inhib. hit(s) with Target = 'Retinoic acid receptor gamma'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Retinoid receptor


(Homo sapiens)
BDBM31883
PNG
(9-cis-retinoic acid (9cRA) | ALL-TRANS-RETINOIC AC...)
Show SMILES C\C(\C=C\C1=C(C)CCCC1(C)C)=C/C=C/C(/C)=C/C(O)=O
Show InChI InChI=1S/C20H28O2/c1-15(8-6-9-16(2)14-19(21)22)11-12-18-17(3)10-7-13-20(18,4)5/h6,8-9,11-12,14H,7,10,13H2,1-5H3,(H,21,22)/b9-6+,12-11+,15-8+,16-14+
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0.0400n/an/an/an/an/an/an/an/a



University of Tokyo

Curated by ChEMBL


Assay Description
Agonistic activity of the compound towards retinoic acid receptor-gamma


J Med Chem 40: 4222-34 (1998)


Article DOI: 10.1021/jm9704309
BindingDB Entry DOI: 10.7270/Q21J98VC
More data for this
Ligand-Target Pair
Retinoid receptor


(Homo sapiens)
BDBM31883
PNG
(9-cis-retinoic acid (9cRA) | ALL-TRANS-RETINOIC AC...)
Show SMILES C\C(\C=C\C1=C(C)CCCC1(C)C)=C/C=C/C(/C)=C/C(O)=O
Show InChI InChI=1S/C20H28O2/c1-15(8-6-9-16(2)14-19(21)22)11-12-18-17(3)10-7-13-20(18,4)5/h6,8-9,11-12,14H,7,10,13H2,1-5H3,(H,21,22)/b9-6+,12-11+,15-8+,16-14+
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0.5n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of [3H]-RA to binding Retinoic acid receptor RAR gamma


Bioorg Med Chem Lett 4: 2117-2122 (1994)


Article DOI: 10.1016/S0960-894X(01)80113-X
BindingDB Entry DOI: 10.7270/Q2V40V4W
More data for this
Ligand-Target Pair
Retinoid receptor


(Homo sapiens)
BDBM31883
PNG
(9-cis-retinoic acid (9cRA) | ALL-TRANS-RETINOIC AC...)
Show SMILES C\C(\C=C\C1=C(C)CCCC1(C)C)=C/C=C/C(/C)=C/C(O)=O
Show InChI InChI=1S/C20H28O2/c1-15(8-6-9-16(2)14-19(21)22)11-12-18-17(3)10-7-13-20(18,4)5/h6,8-9,11-12,14H,7,10,13H2,1-5H3,(H,21,22)/b9-6+,12-11+,15-8+,16-14+
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0.600n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity towards human Retinoic acid receptor gamma


Bioorg Med Chem Lett 7: 2313-2318 (1997)


Article DOI: 10.1016/S0960-894X(97)00420-4
BindingDB Entry DOI: 10.7270/Q2Z89CDD
More data for this
Ligand-Target Pair
Retinoid receptor


(Homo sapiens)
BDBM31883
PNG
(9-cis-retinoic acid (9cRA) | ALL-TRANS-RETINOIC AC...)
Show SMILES C\C(\C=C\C1=C(C)CCCC1(C)C)=C/C=C/C(/C)=C/C(O)=O
Show InChI InChI=1S/C20H28O2/c1-15(8-6-9-16(2)14-19(21)22)11-12-18-17(3)10-7-13-20(18,4)5/h6,8-9,11-12,14H,7,10,13H2,1-5H3,(H,21,22)/b9-6+,12-11+,15-8+,16-14+
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0.700n/an/an/an/an/an/an/an/a



The Ohio State University

Curated by ChEMBL


Assay Description
Binding affinity against Retinoic acid receptor gamma


Bioorg Med Chem Lett 11: 1583-6 (2001)


Article DOI: 10.1016/s0960-894x(01)00230-x
BindingDB Entry DOI: 10.7270/Q20R9NQW
More data for this
Ligand-Target Pair
Retinoid receptor


(Homo sapiens)
BDBM31892
PNG
(9-cis retinoic acid | 9C-RA | CHEMBL705 | Panretin...)
Show SMILES C\C(\C=C\C1=C(C)CCCC1(C)C)=C\C=C\C(\C)=C\C(O)=O
Show InChI InChI=1S/C20H28O2/c1-15(8-6-9-16(2)14-19(21)22)11-12-18-17(3)10-7-13-20(18,4)5/h6,8-9,11-12,14H,7,10,13H2,1-5H3,(H,21,22)/b9-6+,12-11+,15-8-,16-14+
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1n/an/an/an/an/an/an/an/a



University of Tokyo

Curated by ChEMBL


Assay Description
Agonistic activity of the compound towards retinoic acid receptor-gamma


J Med Chem 40: 4222-34 (1998)


Article DOI: 10.1021/jm9704309
BindingDB Entry DOI: 10.7270/Q21J98VC
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Retinoid receptor


(Homo sapiens)
BDBM50052033
PNG
((2E,4E,6E)-7-(3,5-Di-tert-butyl-phenyl)-3-methyl-o...)
Show SMILES C\C(\C=C\C=C(/C)c1cc(cc(c1)C(C)(C)C)C(C)(C)C)=C/C(O)=O
Show InChI InChI=1S/C23H32O2/c1-16(12-21(24)25)10-9-11-17(2)18-13-19(22(3,4)5)15-20(14-18)23(6,7)8/h9-15H,1-8H3,(H,24,25)/b10-9+,16-12+,17-11+
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1.90n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Inhibition of [3H]-ATRA binding to Retinoic acid receptor RAR gamma


J Med Chem 39: 2659-63 (1996)


Article DOI: 10.1021/jm960285j
BindingDB Entry DOI: 10.7270/Q2988631
More data for this
Ligand-Target Pair
Retinoid receptor


(Homo sapiens)
BDBM50052033
PNG
((2E,4E,6E)-7-(3,5-Di-tert-butyl-phenyl)-3-methyl-o...)
Show SMILES C\C(\C=C\C=C(/C)c1cc(cc(c1)C(C)(C)C)C(C)(C)C)=C/C(O)=O
Show InChI InChI=1S/C23H32O2/c1-16(12-21(24)25)10-9-11-17(2)18-13-19(22(3,4)5)15-20(14-18)23(6,7)8/h9-15H,1-8H3,(H,24,25)/b10-9+,16-12+,17-11+
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1.90n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Inhibition of [3H]-ATRA binding to Retinoic acid receptor RAR gamma


J Med Chem 39: 2659-63 (1996)


Article DOI: 10.1021/jm960285j
BindingDB Entry DOI: 10.7270/Q2988631
More data for this
Ligand-Target Pair
Retinoid receptor


(Homo sapiens)
BDBM50048296
PNG
(4-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-anthrace...)
Show SMILES CC1(C)CCC(C)(C)c2cc3cc(ccc3cc12)-c1ccc(cc1)C(O)=O
Show InChI InChI=1S/C25H26O2/c1-24(2)11-12-25(3,4)22-15-20-13-18(9-10-19(20)14-21(22)24)16-5-7-17(8-6-16)23(26)27/h5-10,13-15H,11-12H2,1-4H3,(H,26,27)
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2n/an/an/an/an/an/an/an/a



CIRD GALDERMA

Curated by ChEMBL


Assay Description
Binding affinity to retinoic acid receptor (RAR) gamma using [3H]-CD 367 as radioligand


J Med Chem 38: 4993-5006 (1996)


Article DOI: 10.1021/jm00026a006
BindingDB Entry DOI: 10.7270/Q20G3J8S
More data for this
Ligand-Target Pair
Retinoid receptor


(Homo sapiens)
BDBM31883
PNG
(9-cis-retinoic acid (9cRA) | ALL-TRANS-RETINOIC AC...)
Show SMILES C\C(\C=C\C1=C(C)CCCC1(C)C)=C/C=C/C(/C)=C/C(O)=O
Show InChI InChI=1S/C20H28O2/c1-15(8-6-9-16(2)14-19(21)22)11-12-18-17(3)10-7-13-20(18,4)5/h6,8-9,11-12,14H,7,10,13H2,1-5H3,(H,21,22)/b9-6+,12-11+,15-8+,16-14+
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3n/an/an/an/an/an/an/an/a



CIRD GALDERMA

Curated by ChEMBL


Assay Description
Binding affinity to retinoic acid receptor (RAR) gamma using [3H]-CD 367 as radioligand


J Med Chem 38: 4993-5006 (1996)


Article DOI: 10.1021/jm00026a006
BindingDB Entry DOI: 10.7270/Q20G3J8S
More data for this
Ligand-Target Pair
Retinoid receptor


(Homo sapiens)
BDBM50032219
PNG
((E)-4-(2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydrona...)
Show SMILES C\C(=C/c1ccc(cc1)C(O)=O)c1ccc2c(c1)C(C)(C)CCC2(C)C
Show InChI InChI=1S/C24H28O2/c1-16(14-17-6-8-18(9-7-17)22(25)26)19-10-11-20-21(15-19)24(4,5)13-12-23(20,2)3/h6-11,14-15H,12-13H2,1-5H3,(H,25,26)/b16-14+
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5n/an/an/an/an/an/an/an/a



CIRD GALDERMA

Curated by ChEMBL


Assay Description
Binding affinity to retinoic acid receptor (RAR) gamma using [3H]-CD 367 as radioligand


J Med Chem 38: 4993-5006 (1996)


Article DOI: 10.1021/jm00026a006
BindingDB Entry DOI: 10.7270/Q20G3J8S
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Retinoid receptor


(Homo sapiens)
BDBM50048295
PNG
(4-[(E)-2-(3-tert-Butyl-4-methoxy-phenyl)-propenyl]...)
Show SMILES COc1ccc(cc1C(C)(C)C)C(\C)=C\c1ccc(cc1)C(O)=O
Show InChI InChI=1S/C21H24O3/c1-14(12-15-6-8-16(9-7-15)20(22)23)17-10-11-19(24-5)18(13-17)21(2,3)4/h6-13H,1-5H3,(H,22,23)/b14-12+
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13n/an/an/an/an/an/an/an/a



CIRD GALDERMA

Curated by ChEMBL


Assay Description
Binding affinity to retinoic acid receptor (RAR) gamma using [3H]-CD 367 as radioligand


J Med Chem 38: 4993-5006 (1996)


Article DOI: 10.1021/jm00026a006
BindingDB Entry DOI: 10.7270/Q20G3J8S
More data for this
Ligand-Target Pair
Retinoid receptor


(Homo sapiens)
BDBM31883
PNG
(9-cis-retinoic acid (9cRA) | ALL-TRANS-RETINOIC AC...)
Show SMILES C\C(\C=C\C1=C(C)CCCC1(C)C)=C/C=C/C(/C)=C/C(O)=O
Show InChI InChI=1S/C20H28O2/c1-15(8-6-9-16(2)14-19(21)22)11-12-18-17(3)10-7-13-20(18,4)5/h6,8-9,11-12,14H,7,10,13H2,1-5H3,(H,21,22)/b9-6+,12-11+,15-8+,16-14+
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19n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Inhibition of [3H]-ATRA binding to Retinoic acid receptor RAR gamma


J Med Chem 39: 2659-63 (1996)


Article DOI: 10.1021/jm960285j
BindingDB Entry DOI: 10.7270/Q2988631
More data for this
Ligand-Target Pair
Retinoid receptor


(Homo sapiens)
BDBM50290081
PNG
(3-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-naphthal...)
Show SMILES CC1(C)CCC(C)(C)c2cc(ccc12)C1=Cc2ccc(cc2OC1)C(O)=O
Show InChI InChI=1S/C24H26O3/c1-23(2)9-10-24(3,4)20-12-15(7-8-19(20)23)18-11-16-5-6-17(22(25)26)13-21(16)27-14-18/h5-8,11-13H,9-10,14H2,1-4H3,(H,25,26)
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19n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity towards Retinoic acid receptor gamma


Bioorg Med Chem Lett 7: 2289-2294 (1997)


Article DOI: 10.1016/S0960-894X(97)00405-8
BindingDB Entry DOI: 10.7270/Q2HD7W4M
More data for this
Ligand-Target Pair
Retinoid receptor


(Homo sapiens)
BDBM50048278
PNG
(4-[(E)-2-(3-Adamantan-1-yl-4-hydroxy-phenyl)-vinyl...)
Show SMILES OC(=O)c1ccc(\C=C\c2ccc(O)c(c2)C23CC4CC(CC(C4)C2)C3)cc1
Show InChI InChI=1S/C25H26O3/c26-23-8-5-17(2-1-16-3-6-21(7-4-16)24(27)28)12-22(23)25-13-18-9-19(14-25)11-20(10-18)15-25/h1-8,12,18-20,26H,9-11,13-15H2,(H,27,28)/b2-1+
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20n/an/an/an/an/an/an/an/a



CIRD GALDERMA

Curated by ChEMBL


Assay Description
Binding affinity to retinoic acid receptor (RAR) gamma using [3H]-CD 367 as radioligand


J Med Chem 38: 4993-5006 (1996)


Article DOI: 10.1021/jm00026a006
BindingDB Entry DOI: 10.7270/Q20G3J8S
More data for this
Ligand-Target Pair
Retinoid receptor


(Homo sapiens)
BDBM31892
PNG
(9-cis retinoic acid | 9C-RA | CHEMBL705 | Panretin...)
Show SMILES C\C(\C=C\C1=C(C)CCCC1(C)C)=C\C=C\C(\C)=C\C(O)=O
Show InChI InChI=1S/C20H28O2/c1-15(8-6-9-16(2)14-19(21)22)11-12-18-17(3)10-7-13-20(18,4)5/h6,8-9,11-12,14H,7,10,13H2,1-5H3,(H,21,22)/b9-6+,12-11+,15-8-,16-14+
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20n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Inhibition of [3H]-ATRA binding to Retinoic acid receptor RAR gamma


J Med Chem 39: 2659-63 (1996)


Article DOI: 10.1021/jm960285j
BindingDB Entry DOI: 10.7270/Q2988631
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Retinoid receptor


(Homo sapiens)
BDBM50048293
PNG
(4-{(E)-2-[4-Hydroxy-3-(1-methyl-cyclohexyl)-phenyl...)
Show SMILES C\C(=C/c1ccc(cc1)C(O)=O)c1ccc(O)c(c1)C1(C)CCCCC1
Show InChI InChI=1S/C23H26O3/c1-16(14-17-6-8-18(9-7-17)22(25)26)19-10-11-21(24)20(15-19)23(2)12-4-3-5-13-23/h6-11,14-15,24H,3-5,12-13H2,1-2H3,(H,25,26)/b16-14+
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27n/an/an/an/an/an/an/an/a



CIRD GALDERMA

Curated by ChEMBL


Assay Description
Binding affinity to retinoic acid receptor (RAR) gamma using [3H]-CD 367 as radioligand


J Med Chem 38: 4993-5006 (1996)


Article DOI: 10.1021/jm00026a006
BindingDB Entry DOI: 10.7270/Q20G3J8S
More data for this
Ligand-Target Pair
Retinoid receptor


(Homo sapiens)
BDBM50048285
PNG
(4-{(E)-2-[4-Methoxy-3-(1-methyl-cyclohexyl)-phenyl...)
Show SMILES COc1ccc(cc1C1(C)CCCCC1)C(\C)=C\c1ccc(cc1)C(O)=O
Show InChI InChI=1S/C24H28O3/c1-17(15-18-7-9-19(10-8-18)23(25)26)20-11-12-22(27-3)21(16-20)24(2)13-5-4-6-14-24/h7-12,15-16H,4-6,13-14H2,1-3H3,(H,25,26)/b17-15+
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29n/an/an/an/an/an/an/an/a



CIRD GALDERMA

Curated by ChEMBL


Assay Description
Binding affinity to retinoic acid receptor (RAR) gamma using [3H]-CD 367 as radioligand


J Med Chem 38: 4993-5006 (1996)


Article DOI: 10.1021/jm00026a006
BindingDB Entry DOI: 10.7270/Q20G3J8S
More data for this
Ligand-Target Pair
Retinoid receptor


(Homo sapiens)
BDBM50290137
PNG
((2E,4E)-3-Methyl-5-{2-[(E)-2-(3,3,6,6-tetramethyl-...)
Show SMILES C\C(\C=C\C1CC1\C=C\C1=CC(C)(C)CCC1(C)C)=C/C(O)=O
Show InChI InChI=1S/C21H30O2/c1-15(12-19(22)23)6-7-16-13-17(16)8-9-18-14-20(2,3)10-11-21(18,4)5/h6-9,12,14,16-17H,10-11,13H2,1-5H3,(H,22,23)/b7-6+,9-8+,15-12+
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32n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity towards human Retinoic acid receptor gamma


Bioorg Med Chem Lett 7: 2313-2318 (1997)


Article DOI: 10.1016/S0960-894X(97)00420-4
BindingDB Entry DOI: 10.7270/Q2Z89CDD
More data for this
Ligand-Target Pair
Retinoid receptor


(Homo sapiens)
BDBM50048289
PNG
(6-[3-Adamantan-1-yl-4-(2,3-dihydroxy-propyl)-pheny...)
Show SMILES OCC(O)Cc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O
Show InChI InChI=1S/C30H32O4/c31-17-27(32)12-25-5-3-24(22-1-2-23-11-26(29(33)34)6-4-21(23)10-22)13-28(25)30-14-18-7-19(15-30)9-20(8-18)16-30/h1-6,10-11,13,18-20,27,31-32H,7-9,12,14-17H2,(H,33,34)
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34n/an/an/an/an/an/an/an/a



CIRD GALDERMA

Curated by ChEMBL


Assay Description
Binding affinity to retinoic acid receptor (RAR) gamma using [3H]-CD 367 as radioligand


J Med Chem 38: 4993-5006 (1996)


Article DOI: 10.1021/jm00026a006
BindingDB Entry DOI: 10.7270/Q20G3J8S
More data for this
Ligand-Target Pair
Retinoid receptor


(Homo sapiens)
BDBM50048281
PNG
(5',5',8',8'-Tetramethyl-5',6',7',8'-tetrahydro-[2,...)
Show SMILES CC1(C)CCC(C)(C)c2cc(ccc12)-c1ccc2cc(ccc2c1)C(O)=O
Show InChI InChI=1S/C25H26O2/c1-24(2)11-12-25(3,4)22-15-19(9-10-21(22)24)17-5-6-18-14-20(23(26)27)8-7-16(18)13-17/h5-10,13-15H,11-12H2,1-4H3,(H,26,27)
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40n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity towards Retinoic acid receptor gamma


Bioorg Med Chem Lett 7: 2289-2294 (1997)


Article DOI: 10.1016/S0960-894X(97)00405-8
BindingDB Entry DOI: 10.7270/Q2HD7W4M
More data for this
Ligand-Target Pair
Retinoid receptor


(Homo sapiens)
BDBM50048281
PNG
(5',5',8',8'-Tetramethyl-5',6',7',8'-tetrahydro-[2,...)
Show SMILES CC1(C)CCC(C)(C)c2cc(ccc12)-c1ccc2cc(ccc2c1)C(O)=O
Show InChI InChI=1S/C25H26O2/c1-24(2)11-12-25(3,4)22-15-19(9-10-21(22)24)17-5-6-18-14-20(23(26)27)8-7-16(18)13-17/h5-10,13-15H,11-12H2,1-4H3,(H,26,27)
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40n/an/an/an/an/an/an/an/a



CIRD GALDERMA

Curated by ChEMBL


Assay Description
Binding affinity to retinoic acid receptor (RAR) gamma using [3H]-CD 367 as radioligand


J Med Chem 38: 4993-5006 (1996)


Article DOI: 10.1021/jm00026a006
BindingDB Entry DOI: 10.7270/Q20G3J8S
More data for this
Ligand-Target Pair
Retinoid receptor


(Homo sapiens)
BDBM50048276
PNG
(4-[(E)-2-(3-Adamantan-1-yl-4-hydroxy-phenyl)-prope...)
Show SMILES C\C(=C/c1ccc(cc1)C(O)=O)c1ccc(O)c(c1)C12CC3CC(CC(C3)C1)C2
Show InChI InChI=1S/C26H28O3/c1-16(8-17-2-4-21(5-3-17)25(28)29)22-6-7-24(27)23(12-22)26-13-18-9-19(14-26)11-20(10-18)15-26/h2-8,12,18-20,27H,9-11,13-15H2,1H3,(H,28,29)/b16-8+
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53n/an/an/an/an/an/an/an/a



CIRD GALDERMA

Curated by ChEMBL


Assay Description
Binding affinity to retinoic acid receptor (RAR) gamma using [3H]-CD 367 as radioligand


J Med Chem 38: 4993-5006 (1996)


Article DOI: 10.1021/jm00026a006
BindingDB Entry DOI: 10.7270/Q20G3J8S
More data for this
Ligand-Target Pair
Retinoid receptor


(Homo sapiens)
BDBM50048284
PNG
(6-[3-Adamantan-1-yl-4-(3-hydroxy-propyl)-phenyl]-n...)
Show SMILES OCCCc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O
Show InChI InChI=1S/C30H32O3/c31-9-1-2-22-3-4-26(24-5-6-25-14-27(29(32)33)8-7-23(25)13-24)15-28(22)30-16-19-10-20(17-30)12-21(11-19)18-30/h3-8,13-15,19-21,31H,1-2,9-12,16-18H2,(H,32,33)
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72n/an/an/an/an/an/an/an/a



CIRD GALDERMA

Curated by ChEMBL


Assay Description
Binding affinity to retinoic acid receptor (RAR) gamma using [3H]-CD 367 as radioligand


J Med Chem 38: 4993-5006 (1996)


Article DOI: 10.1021/jm00026a006
BindingDB Entry DOI: 10.7270/Q20G3J8S
More data for this
Ligand-Target Pair
Retinoid receptor


(Homo sapiens)
BDBM50048291
PNG
(6-(3-Adamantan-1-yl-4-hydroxy-phenyl)-naphthalene-...)
Show SMILES OC(=O)c1ccc2cc(ccc2c1)-c1ccc(O)c(c1)C12CC3CC(CC(C3)C1)C2
Show InChI InChI=1S/C27H26O3/c28-25-6-5-22(20-1-2-21-11-23(26(29)30)4-3-19(21)10-20)12-24(25)27-13-16-7-17(14-27)9-18(8-16)15-27/h1-6,10-12,16-18,28H,7-9,13-15H2,(H,29,30)
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77n/an/an/an/an/an/an/an/a



CIRD GALDERMA

Curated by ChEMBL


Assay Description
Binding affinity to retinoic acid receptor (RAR) gamma using [3H]-CD 367 as radioligand


J Med Chem 38: 4993-5006 (1996)


Article DOI: 10.1021/jm00026a006
BindingDB Entry DOI: 10.7270/Q20G3J8S
More data for this
Ligand-Target Pair
Retinoid receptor


(Homo sapiens)
BDBM50048290
PNG
(4-[(E)-2-(3-tert-Butyl-4-hydroxy-phenyl)-propenyl]...)
Show SMILES C\C(=C/c1ccc(cc1)C(O)=O)c1ccc(O)c(c1)C(C)(C)C
Show InChI InChI=1S/C20H22O3/c1-13(11-14-5-7-15(8-6-14)19(22)23)16-9-10-18(21)17(12-16)20(2,3)4/h5-12,21H,1-4H3,(H,22,23)/b13-11+
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85n/an/an/an/an/an/an/an/a



CIRD GALDERMA

Curated by ChEMBL


Assay Description
Binding affinity to retinoic acid receptor (RAR) gamma using [3H]-CD 367 as radioligand


J Med Chem 38: 4993-5006 (1996)


Article DOI: 10.1021/jm00026a006
BindingDB Entry DOI: 10.7270/Q20G3J8S
More data for this
Ligand-Target Pair
Retinoid receptor


(Homo sapiens)
BDBM50048277
PNG
(4-[(E)-2-(3-Adamantan-1-yl-4-methoxy-phenyl)-prope...)
Show SMILES COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)C(\C)=C\c1ccc(cc1)C(O)=O
Show InChI InChI=1S/C27H30O3/c1-17(9-18-3-5-22(6-4-18)26(28)29)23-7-8-25(30-2)24(13-23)27-14-19-10-20(15-27)12-21(11-19)16-27/h3-9,13,19-21H,10-12,14-16H2,1-2H3,(H,28,29)/b17-9+
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95n/an/an/an/an/an/an/an/a



CIRD GALDERMA

Curated by ChEMBL


Assay Description
Binding affinity to retinoic acid receptor (RAR) gamma using [3H]-CD 367 as radioligand


J Med Chem 38: 4993-5006 (1996)


Article DOI: 10.1021/jm00026a006
BindingDB Entry DOI: 10.7270/Q20G3J8S
More data for this
Ligand-Target Pair
Retinoid receptor


(Homo sapiens)
BDBM50048287
PNG
(6-[4-Hydroxy-3-(1-methyl-cyclohexyl)-phenyl]-napht...)
Show SMILES CC1(CCCCC1)c1cc(ccc1O)-c1ccc2cc(ccc2c1)C(O)=O
Show InChI InChI=1S/C24H24O3/c1-24(11-3-2-4-12-24)21-15-19(9-10-22(21)25)17-5-6-18-14-20(23(26)27)8-7-16(18)13-17/h5-10,13-15,25H,2-4,11-12H2,1H3,(H,26,27)
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121n/an/an/an/an/an/an/an/a



CIRD GALDERMA

Curated by ChEMBL


Assay Description
Binding affinity to retinoic acid receptor (RAR) gamma using [3H]-CD 367 as radioligand


J Med Chem 38: 4993-5006 (1996)


Article DOI: 10.1021/jm00026a006
BindingDB Entry DOI: 10.7270/Q20G3J8S
More data for this
Ligand-Target Pair
Retinoid receptor


(Homo sapiens)
BDBM50048280
PNG
(6-(3-(1-Adamantyl)-4-methoxyphenyl)-2-naphthoic ac...)
Show SMILES COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O
Show InChI InChI=1S/C28H28O3/c1-31-26-7-6-23(21-2-3-22-12-24(27(29)30)5-4-20(22)11-21)13-25(26)28-14-17-8-18(15-28)10-19(9-17)16-28/h2-7,11-13,17-19H,8-10,14-16H2,1H3,(H,29,30)
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130n/an/an/an/an/an/an/an/a



CIRD GALDERMA

Curated by ChEMBL


Assay Description
Binding affinity to retinoic acid receptor (RAR) gamma using [3H]-CD 367 as radioligand


J Med Chem 38: 4993-5006 (1996)


Article DOI: 10.1021/jm00026a006
BindingDB Entry DOI: 10.7270/Q20G3J8S
More data for this
Ligand-Target Pair
Retinoid receptor


(Homo sapiens)
BDBM50048280
PNG
(6-(3-(1-Adamantyl)-4-methoxyphenyl)-2-naphthoic ac...)
Show SMILES COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O
Show InChI InChI=1S/C28H28O3/c1-31-26-7-6-23(21-2-3-22-12-24(27(29)30)5-4-20(22)11-21)13-25(26)28-14-17-8-18(15-28)10-19(9-17)16-28/h2-7,11-13,17-19H,8-10,14-16H2,1H3,(H,29,30)
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130n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity towards Retinoic acid receptor gamma


Bioorg Med Chem Lett 7: 2289-2294 (1997)


Article DOI: 10.1016/S0960-894X(97)00405-8
BindingDB Entry DOI: 10.7270/Q2HD7W4M
More data for this
Ligand-Target Pair
Retinoid receptor


(Homo sapiens)
BDBM50032675
PNG
(4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaph...)
Show SMILES Cc1cc2c(cc1C(=C)c1ccc(cc1)C(O)=O)C(C)(C)CCC2(C)C
Show InChI InChI=1S/C24H28O2/c1-15-13-20-21(24(5,6)12-11-23(20,3)4)14-19(15)16(2)17-7-9-18(10-8-17)22(25)26/h7-10,13-14H,2,11-12H2,1,3-6H3,(H,25,26)
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130n/an/an/an/an/an/an/an/a



University of Tokyo

Curated by ChEMBL


Assay Description
Selective activity of the compound towards retinoic acid receptor-gamma


J Med Chem 40: 4222-34 (1998)


Article DOI: 10.1021/jm9704309
BindingDB Entry DOI: 10.7270/Q21J98VC
More data for this
Ligand-Target Pair
Retinoid receptor


(Homo sapiens)
BDBM50290078
PNG
(3-(3-Adamantan-1-yl-4-hydroxy-phenyl)-2H-chromene-...)
Show SMILES OC(=O)c1ccc2C=C(COc2c1)c1ccc(O)c(c1)C12C[C@H]3C[C@H](C[C@H](C3)C1)C2
Show InChI InChI=1S/C26H26O4/c27-23-4-3-18(21-8-19-1-2-20(25(28)29)10-24(19)30-14-21)9-22(23)26-11-15-5-16(12-26)7-17(6-15)13-26/h1-4,8-10,15-17,27H,5-7,11-14H2,(H,28,29)/t15-,16+,17-,26?
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148n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity towards Retinoic acid receptor gamma


Bioorg Med Chem Lett 7: 2289-2294 (1997)


Article DOI: 10.1016/S0960-894X(97)00405-8
BindingDB Entry DOI: 10.7270/Q2HD7W4M
More data for this
Ligand-Target Pair
Retinoid receptor


(Homo sapiens)
BDBM50048297
PNG
(6-[3-Adamantan-1-yl-4-(2,3-dihydroxy-propoxy)-phen...)
Show SMILES OCC(O)COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O
Show InChI InChI=1S/C30H32O5/c31-16-26(32)17-35-28-6-5-24(22-1-2-23-11-25(29(33)34)4-3-21(23)10-22)12-27(28)30-13-18-7-19(14-30)9-20(8-18)15-30/h1-6,10-12,18-20,26,31-32H,7-9,13-17H2,(H,33,34)
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151n/an/an/an/an/an/an/an/a



CIRD GALDERMA

Curated by ChEMBL


Assay Description
Binding affinity to retinoic acid receptor (RAR) gamma using [3H]-CD 367 as radioligand


J Med Chem 38: 4993-5006 (1996)


Article DOI: 10.1021/jm00026a006
BindingDB Entry DOI: 10.7270/Q20G3J8S
More data for this
Ligand-Target Pair
Retinoid receptor


(Homo sapiens)
BDBM50048282
PNG
(6-[3-Adamantan-1-yl-4-(1,2-dihydroxy-ethyl)-phenyl...)
Show SMILES OCC(O)c1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O
Show InChI InChI=1S/C29H30O4/c30-16-27(31)25-6-5-23(21-1-2-22-11-24(28(32)33)4-3-20(22)10-21)12-26(25)29-13-17-7-18(14-29)9-19(8-17)15-29/h1-6,10-12,17-19,27,30-31H,7-9,13-16H2,(H,32,33)
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153n/an/an/an/an/an/an/an/a



CIRD GALDERMA

Curated by ChEMBL


Assay Description
Binding affinity to retinoic acid receptor (RAR) gamma using [3H]-CD 367 as radioligand


J Med Chem 38: 4993-5006 (1996)


Article DOI: 10.1021/jm00026a006
BindingDB Entry DOI: 10.7270/Q20G3J8S
More data for this
Ligand-Target Pair
Retinoid receptor


(Homo sapiens)
BDBM50048292
PNG
(6-[4-Methoxy-3-(1-methyl-cyclohexyl)-phenyl]-napht...)
Show SMILES COc1ccc(cc1C1(C)CCCCC1)-c1ccc2cc(ccc2c1)C(O)=O
Show InChI InChI=1S/C25H26O3/c1-25(12-4-3-5-13-25)22-16-20(10-11-23(22)28-2)18-6-7-19-15-21(24(26)27)9-8-17(19)14-18/h6-11,14-16H,3-5,12-13H2,1-2H3,(H,26,27)
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160n/an/an/an/an/an/an/an/a



CIRD GALDERMA

Curated by ChEMBL


Assay Description
Binding affinity to retinoic acid receptor (RAR) gamma using [3H]-CD 367 as radioligand


J Med Chem 38: 4993-5006 (1996)


Article DOI: 10.1021/jm00026a006
BindingDB Entry DOI: 10.7270/Q20G3J8S
More data for this
Ligand-Target Pair
Retinoid receptor


(Homo sapiens)
BDBM50290082
PNG
(3-(3-Adamantan-1-yl-4-methoxy-phenyl)-2H-chromene-...)
Show SMILES COc1ccc(cc1C12C[C@H]3C[C@H](C[C@H](C3)C1)C2)C1=Cc2ccc(cc2OC1)C(O)=O
Show InChI InChI=1S/C27H28O4/c1-30-24-5-4-19(22-9-20-2-3-21(26(28)29)11-25(20)31-15-22)10-23(24)27-12-16-6-17(13-27)8-18(7-16)14-27/h2-5,9-11,16-18H,6-8,12-15H2,1H3,(H,28,29)/t16-,17+,18-,27?
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174n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity towards Retinoic acid receptor gamma


Bioorg Med Chem Lett 7: 2289-2294 (1997)


Article DOI: 10.1016/S0960-894X(97)00405-8
BindingDB Entry DOI: 10.7270/Q2HD7W4M
More data for this
Ligand-Target Pair
Retinoid receptor


(Homo sapiens)
BDBM50048294
PNG
(6-(3-tert-Butyl-4-hydroxy-phenyl)-naphthalene-2-ca...)
Show SMILES CC(C)(C)c1cc(ccc1O)-c1ccc2cc(ccc2c1)C(O)=O
Show InChI InChI=1S/C21H20O3/c1-21(2,3)18-12-16(8-9-19(18)22)14-4-5-15-11-17(20(23)24)7-6-13(15)10-14/h4-12,22H,1-3H3,(H,23,24)
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200n/an/an/an/an/an/an/an/a



CIRD GALDERMA

Curated by ChEMBL


Assay Description
Binding affinity to retinoic acid receptor (RAR) gamma using [3H]-CD 367 as radioligand


J Med Chem 38: 4993-5006 (1996)


Article DOI: 10.1021/jm00026a006
BindingDB Entry DOI: 10.7270/Q20G3J8S
More data for this
Ligand-Target Pair
Retinoid receptor


(Homo sapiens)
BDBM50048294
PNG
(6-(3-tert-Butyl-4-hydroxy-phenyl)-naphthalene-2-ca...)
Show SMILES CC(C)(C)c1cc(ccc1O)-c1ccc2cc(ccc2c1)C(O)=O
Show InChI InChI=1S/C21H20O3/c1-21(2,3)18-12-16(8-9-19(18)22)14-4-5-15-11-17(20(23)24)7-6-13(15)10-14/h4-12,22H,1-3H3,(H,23,24)
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200n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity towards Retinoic acid receptor gamma


Bioorg Med Chem Lett 7: 2289-2294 (1997)


Article DOI: 10.1016/S0960-894X(97)00405-8
BindingDB Entry DOI: 10.7270/Q2HD7W4M
More data for this
Ligand-Target Pair
Retinoid receptor


(Homo sapiens)
BDBM50283073
PNG
(6-[(2E,4E,6E,8E)-3,7-Dimethyl-9-(2,6,6-trimethyl-c...)
Show SMILES C\C(\C=C\C1=C(C)CCCC1(C)C)=C/C=C/C(/C)=C/C(=O)NC1OC(C(O)C(O)C1O)C(O)=O
Show InChI InChI=1S/C26H37NO7/c1-15(11-12-18-17(3)10-7-13-26(18,4)5)8-6-9-16(2)14-19(28)27-24-22(31)20(29)21(30)23(34-24)25(32)33/h6,8-9,11-12,14,20-24,29-31H,7,10,13H2,1-5H3,(H,27,28)(H,32,33)/b9-6+,12-11+,15-8+,16-14+
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280n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of [3H]-RA binding to Retinoic acid receptor RAR gamma


Bioorg Med Chem Lett 4: 2117-2122 (1994)


Article DOI: 10.1016/S0960-894X(01)80113-X
BindingDB Entry DOI: 10.7270/Q2V40V4W
More data for this
Ligand-Target Pair
Retinoid receptor


(Homo sapiens)
BDBM50048283
PNG
(6-(3-Adamantan-1-yl-4-hydroxymethyl-phenyl)-naphth...)
Show SMILES OCc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O
Show InChI InChI=1S/C28H28O3/c29-16-25-6-4-23(21-1-2-22-11-24(27(30)31)5-3-20(22)10-21)12-26(25)28-13-17-7-18(14-28)9-19(8-17)15-28/h1-6,10-12,17-19,29H,7-9,13-16H2,(H,30,31)
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386n/an/an/an/an/an/an/an/a



CIRD GALDERMA

Curated by ChEMBL


Assay Description
Binding affinity to retinoic acid receptor (RAR) gamma using [3H]-CD 367 as radioligand


J Med Chem 38: 4993-5006 (1996)


Article DOI: 10.1021/jm00026a006
BindingDB Entry DOI: 10.7270/Q20G3J8S
More data for this
Ligand-Target Pair
Retinoid receptor


(Homo sapiens)
BDBM50092055
PNG
((2E,4E,6E,8E)-3,7-Dimethyl-9-(2,6,6-trimethyl-cycl...)
Show SMILES C\C(\C=C\C1=C(C)CCCC1(C)C)=C/C=C/C(/C)=C/C(=O)Nc1ccc(O)cc1
Show InChI InChI=1S/C26H33NO2/c1-19(11-16-24-21(3)10-7-17-26(24,4)5)8-6-9-20(2)18-25(29)27-22-12-14-23(28)15-13-22/h6,8-9,11-16,18,28H,7,10,17H2,1-5H3,(H,27,29)/b9-6+,16-11+,19-8+,20-18+
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>400n/an/an/an/an/an/an/an/a



The Ohio State University

Curated by ChEMBL


Assay Description
Binding affinity against Retinoic acid receptor gamma


Bioorg Med Chem Lett 11: 1583-6 (2001)


Article DOI: 10.1016/s0960-894x(01)00230-x
BindingDB Entry DOI: 10.7270/Q20R9NQW
More data for this
Ligand-Target Pair
Retinoid receptor


(Homo sapiens)
BDBM50048279
PNG
(6-(3-tert-Butyl-4-methoxy-phenyl)-naphthalene-2-ca...)
Show SMILES COc1ccc(cc1C(C)(C)C)-c1ccc2cc(ccc2c1)C(O)=O
Show InChI InChI=1S/C22H22O3/c1-22(2,3)19-13-17(9-10-20(19)25-4)15-5-6-16-12-18(21(23)24)8-7-14(16)11-15/h5-13H,1-4H3,(H,23,24)
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426n/an/an/an/an/an/an/an/a



CIRD GALDERMA

Curated by ChEMBL


Assay Description
Binding affinity to retinoic acid receptor (RAR) gamma using [3H]-CD 367 as radioligand


J Med Chem 38: 4993-5006 (1996)


Article DOI: 10.1021/jm00026a006
BindingDB Entry DOI: 10.7270/Q20G3J8S
More data for this
Ligand-Target Pair
Retinoid receptor


(Homo sapiens)
BDBM50052588
PNG
((2E,4E,6Z)-7-(3-Methoxy-5,5,8,8-tetramethyl-5,6,7,...)
Show SMILES COc1cc2c(cc1\C(C)=C/C=C/C(/C)=C/C(O)=O)C(C)(C)CCC2(C)C
Show InChI InChI=1S/C24H32O3/c1-16(13-22(25)26)9-8-10-17(2)18-14-19-20(15-21(18)27-7)24(5,6)12-11-23(19,3)4/h8-10,13-15H,11-12H2,1-7H3,(H,25,26)/b9-8+,16-13+,17-10-
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437n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Inhibition of [3H]-ATRA binding to Retinoic acid receptor RAR gamma


J Med Chem 39: 3229-34 (1996)


Article DOI: 10.1021/jm960311d
BindingDB Entry DOI: 10.7270/Q2ZW1K14
More data for this
Ligand-Target Pair
Retinoid receptor


(Homo sapiens)
BDBM50061615
PNG
(4-(10,10,13,13,15-Pentamethyl-11,12,13,15-tetrahyd...)
Show SMILES CN1c2cc3c(cc2N=C(c2ccc(cc2)C(O)=O)c2ccc4ccccc4c12)C(C)(C)CCC3(C)C
Show InChI InChI=1S/C33H32N2O2/c1-32(2)16-17-33(3,4)26-19-28-27(18-25(26)32)34-29(21-10-12-22(13-11-21)31(36)37)24-15-14-20-8-6-7-9-23(20)30(24)35(28)5/h6-15,18-19H,16-17H2,1-5H3,(H,36,37)
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490n/an/an/an/an/an/an/an/a



University of Tokyo

Curated by ChEMBL


Assay Description
Antagonistic activity of the compound towards retinoic acid receptor-gamma


J Med Chem 40: 4222-34 (1998)


Article DOI: 10.1021/jm9704309
BindingDB Entry DOI: 10.7270/Q21J98VC
More data for this
Ligand-Target Pair
Retinoid receptor


(Homo sapiens)
BDBM50290083
PNG
(3-(3,5-Di-tert-butyl-4-hydroxy-phenyl)-2H-chromene...)
Show SMILES CC(C)(C)c1cc(cc(c1O)C(C)(C)C)C1=Cc2ccc(cc2OC1)C(O)=O
Show InChI InChI=1S/C24H28O4/c1-23(2,3)18-10-16(11-19(21(18)25)24(4,5)6)17-9-14-7-8-15(22(26)27)12-20(14)28-13-17/h7-12,25H,13H2,1-6H3,(H,26,27)
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531n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity towards Retinoic acid receptor gamma


Bioorg Med Chem Lett 7: 2289-2294 (1997)


Article DOI: 10.1016/S0960-894X(97)00405-8
BindingDB Entry DOI: 10.7270/Q2HD7W4M
More data for this
Ligand-Target Pair
Retinoid receptor


(Homo sapiens)
BDBM50283072
PNG
((2E,4E,6E,8E)-3,7-Dimethyl-9-(2,6,6-trimethyl-cycl...)
Show SMILES C\C(\C=C\C1=C(C)CCCC1(C)C)=C/C=C/C(/C)=C/C(=O)NC1OC(CO)C(O)C(O)C1O
Show InChI InChI=1S/C26H39NO6/c1-16(11-12-19-18(3)10-7-13-26(19,4)5)8-6-9-17(2)14-21(29)27-25-24(32)23(31)22(30)20(15-28)33-25/h6,8-9,11-12,14,20,22-25,28,30-32H,7,10,13,15H2,1-5H3,(H,27,29)/b9-6+,12-11+,16-8+,17-14+
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710n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of [3H]-RA to binding Retinoic acid receptor RAR gamma


Bioorg Med Chem Lett 4: 2117-2122 (1994)


Article DOI: 10.1016/S0960-894X(01)80113-X
BindingDB Entry DOI: 10.7270/Q2V40V4W
More data for this
Ligand-Target Pair
Retinoid receptor


(Homo sapiens)
BDBM50048298
PNG
(6-(4,4-Dimethyl-chroman-6-yl)-naphthalene-2-carbox...)
Show SMILES CC1(C)CCOc2ccc(cc12)-c1ccc2cc(ccc2c1)C(O)=O
Show InChI InChI=1S/C22H20O3/c1-22(2)9-10-25-20-8-7-17(13-19(20)22)15-3-4-16-12-18(21(23)24)6-5-14(16)11-15/h3-8,11-13H,9-10H2,1-2H3,(H,23,24)
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860n/an/an/an/an/an/an/an/a



CIRD GALDERMA

Curated by ChEMBL


Assay Description
Binding affinity to retinoic acid receptor (RAR) gamma using [3H]-CD 367 as radioligand


J Med Chem 38: 4993-5006 (1996)


Article DOI: 10.1021/jm00026a006
BindingDB Entry DOI: 10.7270/Q20G3J8S
More data for this
Ligand-Target Pair
Retinoid receptor


(Homo sapiens)
BDBM50033079
PNG
(4-[1-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-napht...)
Show SMILES CC1(C)CCC(C)(C)c2cc(ccc12)C(=C)c1ccc(cc1)C(O)=O
Show InChI InChI=1S/C23H26O2/c1-15(16-6-8-17(9-7-16)21(24)25)18-10-11-19-20(14-18)23(4,5)13-12-22(19,2)3/h6-11,14H,1,12-13H2,2-5H3,(H,24,25)
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887n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of [3H]-ATRA bindng to RAR gamma receptor


Bioorg Med Chem Lett 7: 2747-2752 (1997)


Article DOI: 10.1016/S0960-894X(97)10079-8
BindingDB Entry DOI: 10.7270/Q2JW8DW6
More data for this
Ligand-Target Pair
Retinoid receptor


(Homo sapiens)
BDBM50290191
PNG
(3-Methyl-5-[2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahy...)
Show SMILES C\C(\C=C\C1=C(CCC1)c1ccc2c(c1)C(C)(C)CCC2(C)C)=C/C(O)=O
Show InChI InChI=1S/C25H32O2/c1-17(15-23(26)27)9-10-18-7-6-8-20(18)19-11-12-21-22(16-19)25(4,5)14-13-24(21,2)3/h9-12,15-16H,6-8,13-14H2,1-5H3,(H,26,27)/b10-9+,17-15+
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>1.00E+3n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of [3H]-ATRA binding to Retinoic acid receptor RAR gamma


Bioorg Med Chem Lett 7: 2393-2398 (1997)


Article DOI: 10.1016/S0960-894X(97)00437-X
BindingDB Entry DOI: 10.7270/Q2FB52XX
More data for this
Ligand-Target Pair
Retinoid receptor


(Homo sapiens)
BDBM50290190
PNG
((2E,4E)-3-Methyl-5-[(1R,2S)-4-methylene-2-(5,5,8,8...)
Show SMILES C\C(\C=C\[C@H]1CC(=C)C[C@@H]1c1ccc2c(c1)C(C)(C)CCC2(C)C)=C/C(O)=O
Show InChI InChI=1S/C26H34O2/c1-17(15-24(27)28)7-8-19-13-18(2)14-21(19)20-9-10-22-23(16-20)26(5,6)12-11-25(22,3)4/h7-10,15-16,19,21H,2,11-14H2,1,3-6H3,(H,27,28)/b8-7+,17-15+/t19-,21-/m0/s1
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>1.00E+3n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of [3H]-ATRA binding to Retinoic acid receptor RAR gamma


Bioorg Med Chem Lett 7: 2393-2398 (1997)


Article DOI: 10.1016/S0960-894X(97)00437-X
BindingDB Entry DOI: 10.7270/Q2FB52XX
More data for this
Ligand-Target Pair
Retinoid receptor


(Homo sapiens)
BDBM50290662
PNG
((2E,4E)-3-Methyl-5-[1-(3,5,5,8,8-pentamethyl-5,6,7...)
Show SMILES C\C(\C=C\C1(CCCC1)c1cc2c(cc1C)C(C)(C)CCC2(C)C)=C/C(O)=O
Show InChI InChI=1S/C26H36O2/c1-18(15-23(27)28)9-12-26(10-7-8-11-26)20-17-22-21(16-19(20)2)24(3,4)13-14-25(22,5)6/h9,12,15-17H,7-8,10-11,13-14H2,1-6H3,(H,27,28)/b12-9+,18-15+
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>1.00E+3n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of [3H]-ATRA bindng to RAR gamma receptor


Bioorg Med Chem Lett 7: 2747-2752 (1997)


Article DOI: 10.1016/S0960-894X(97)10079-8
BindingDB Entry DOI: 10.7270/Q2JW8DW6
More data for this
Ligand-Target Pair
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