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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Ryanodine receptor 1' AND taxid = 10090   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Ryanodine receptor 1


(Mus musculus)
BDBM50222771
PNG
(3-bromo-N-(4-chloro-2-methyl-6-(methylcarbamoyl)ph...)
Show SMILES CNC(=O)c1cc(Cl)cc(C)c1NC(=O)c1cc(Br)nn1-c1ncccc1Cl
Show InChI InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)
PDB
MMDB

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Article
PubMed
n/an/an/an/a 1.40E+4n/an/an/an/a



DuPont Crop Protection

Curated by ChEMBL


Assay Description
Activation of ryanodine receptor 1 in mouse C2C12 cells assessed as induction of calcium mobilization


Bioorg Med Chem 17: 4127-33 (2009)

More data for this
Ligand-Target Pair