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Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'SH2 domain-containing protein 1A' AND taxid = 9606   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
SH2 domain-containing protein 1A


(Homo sapiens)
BDBM50427872
PNG
(CHEMBL2326990)
Show SMILES NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc1ccc2OP(O)(=O)OCc2c1)NC(=O)OCC1c2ccccc2-c2ccccc12
Show InChI InChI=1S/C29H28N3O10P/c30-27(35)23(13-26(33)34)31-28(36)24(12-16-9-10-25-17(11-16)14-41-43(38,39)42-25)32-29(37)40-15-22-20-7-3-1-5-18(20)19-6-2-4-8-21(19)22/h1-11,22-24H,12-15H2,(H2,30,35)(H,31,36)(H,32,37)(H,33,34)(H,38,39)/t23-,24-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 1.70E+4n/an/an/an/an/an/a



National Taiwan University

Curated by ChEMBL


Assay Description
Inhibition of recombinant 6-His-tagged SLAM associated protein SH2 domain (unknown origin) expressed in Escherichia coli BL21(DE3) binding to biotiny...


J Med Chem 56: 2841-9 (2013)

More data for this
Ligand-Target Pair
SH2 domain-containing protein 1A


(Homo sapiens)
BDBM50427871
PNG
(CHEMBL2326995)
Show SMILES CC(C)(C)OC(=O)NCCCC[C@H](NC(=O)[C@H](Cc1ccc2OP(O)(=O)OCc2c1)NC(=O)OCC1c2ccccc2-c2ccccc12)C(N)=O
Show InChI InChI=1S/C36H43N4O10P/c1-36(2,3)49-34(43)38-17-9-8-14-29(32(37)41)39-33(42)30(19-22-15-16-31-23(18-22)20-48-51(45,46)50-31)40-35(44)47-21-28-26-12-6-4-10-24(26)25-11-5-7-13-27(25)28/h4-7,10-13,15-16,18,28-30H,8-9,14,17,19-21H2,1-3H3,(H2,37,41)(H,38,43)(H,39,42)(H,40,44)(H,45,46)/t29-,30-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 3.40E+4n/an/an/an/an/an/a



National Taiwan University

Curated by ChEMBL


Assay Description
Inhibition of recombinant 6-His-tagged SLAM associated protein SH2 domain (unknown origin) expressed in Escherichia coli BL21(DE3) binding to biotiny...


J Med Chem 56: 2841-9 (2013)

More data for this
Ligand-Target Pair
SH2 domain-containing protein 1A


(Homo sapiens)
BDBM50427873
PNG
(CHEMBL2326989)
Show SMILES NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccc2OP(O)(=O)OCc2c1)NC(=O)OCC1c2ccccc2-c2ccccc12
Show InChI InChI=1S/C34H32N3O8P/c35-32(38)29(17-21-8-2-1-3-9-21)36-33(39)30(18-22-14-15-31-23(16-22)19-44-46(41,42)45-31)37-34(40)43-20-28-26-12-6-4-10-24(26)25-11-5-7-13-27(25)28/h1-16,28-30H,17-20H2,(H2,35,38)(H,36,39)(H,37,40)(H,41,42)/t29-,30-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 3.50E+4n/an/an/an/an/an/a



National Taiwan University

Curated by ChEMBL


Assay Description
Inhibition of recombinant 6-His-tagged SLAM associated protein SH2 domain (unknown origin) expressed in Escherichia coli BL21(DE3) binding to biotiny...


J Med Chem 56: 2841-9 (2013)

More data for this
Ligand-Target Pair