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Compile Data Set for Download or QSAR

Found 21 hits Enz. Inhib. hit(s) with Target = 'Serine/threonine protein phosphatase 2A, catalytic subunit, alpha isoform' AND taxid = 9913   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serine/threonine protein phosphatase 2A, catalytic subunit, alpha isoform


(Bos taurus)
BDBM50135699
PNG
((10S,13S,18S,19S,22R)-8-Isobutyl-18-((1E,3E)-(5S,6...)
Show SMILES CO[C@@H](Cc1ccccc1)[C@@H](C)\C=C(/C)\C=C\[C@@H]1NC(=O)[C@H](C)NC(=O)[C@@H](C)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](C)NC(=O)C(=C)N(C)C(=O)CC[C@@H](NC(=O)[C@H]1C)C(O)=O)C(O)=O
Show InChI InChI=1S/C46H67N7O12/c1-24(2)21-35-44(60)52-38(46(63)64)28(6)40(56)47-29(7)41(57)49-33(18-17-25(3)22-26(4)36(65-11)23-32-15-13-12-14-16-32)27(5)39(55)50-34(45(61)62)19-20-37(54)53(10)31(9)43(59)48-30(8)42(58)51-35/h12-18,22,24,26-30,33-36,38H,9,19-21,23H2,1-8,10-11H3,(H,47,56)(H,48,59)(H,49,57)(H,50,55)(H,51,58)(H,52,60)(H,61,62)(H,63,64)/b18-17+,25-22+/t26-,27-,28-,29-,30+,33-,34+,35-,36-,38+/m0/s1
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PubMed
n/an/a 0.300n/an/an/an/an/an/a



University of California at Irvine

Curated by ChEMBL


Assay Description
Inhibitory concentration of the compound against protein phosphatase 2A (PP2A) using phosphorylase-a assay


Bioorg Med Chem Lett 13: 2907-11 (2003)

More data for this
Ligand-Target Pair
Serine/threonine protein phosphatase 2A, catalytic subunit, alpha isoform


(Bos taurus)
BDBM50135699
PNG
((10S,13S,18S,19S,22R)-8-Isobutyl-18-((1E,3E)-(5S,6...)
Show SMILES CO[C@@H](Cc1ccccc1)[C@@H](C)\C=C(/C)\C=C\[C@@H]1NC(=O)[C@H](C)NC(=O)[C@@H](C)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](C)NC(=O)C(=C)N(C)C(=O)CC[C@@H](NC(=O)[C@H]1C)C(O)=O)C(O)=O
Show InChI InChI=1S/C46H67N7O12/c1-24(2)21-35-44(60)52-38(46(63)64)28(6)40(56)47-29(7)41(57)49-33(18-17-25(3)22-26(4)36(65-11)23-32-15-13-12-14-16-32)27(5)39(55)50-34(45(61)62)19-20-37(54)53(10)31(9)43(59)48-30(8)42(58)51-35/h12-18,22,24,26-30,33-36,38H,9,19-21,23H2,1-8,10-11H3,(H,47,56)(H,48,59)(H,49,57)(H,50,55)(H,51,58)(H,52,60)(H,61,62)(H,63,64)/b18-17+,25-22+/t26-,27-,28-,29-,30+,33-,34+,35-,36-,38+/m0/s1
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PubMed
n/an/a 3n/an/an/an/an/an/a



University of California at Irvine

Curated by ChEMBL


Assay Description
Inhibitory concentration against protein phosphatase 2A (PP2A) using pNPP assay


Bioorg Med Chem Lett 13: 2907-11 (2003)

More data for this
Ligand-Target Pair
Serine/threonine protein phosphatase 2A, catalytic subunit, alpha isoform


(Bos taurus)
BDBM50135691
PNG
((R)-2-((4E,6E)-(2S,3S,8S,9S)-3-Acetylamino-9-metho...)
Show SMILES CO[C@@H](Cc1ccccc1)[C@@H](C)\C=C(/C)\C=C\[C@H](NC(C)=O)[C@H](C)C(=O)N[C@H](C)C(O)=O
Show InChI InChI=1S/C25H36N2O5/c1-16(14-17(2)23(32-6)15-21-10-8-7-9-11-21)12-13-22(27-20(5)28)18(3)24(29)26-19(4)25(30)31/h7-14,17-19,22-23H,15H2,1-6H3,(H,26,29)(H,27,28)(H,30,31)/b13-12+,16-14+/t17-,18-,19+,22-,23-/m0/s1
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n/an/a 160n/an/an/an/an/an/a



University of California at Irvine

Curated by ChEMBL


Assay Description
Inhibitory concentration of the compound against protein phosphatase 2A (PP2A) using phosphorylase-a assay


Bioorg Med Chem Lett 13: 2907-11 (2003)

More data for this
Ligand-Target Pair
Serine/threonine protein phosphatase 2A, catalytic subunit, alpha isoform


(Bos taurus)
BDBM50135697
PNG
(((4E,6E)-(2S,3S,8S,9S)-3-Acetylamino-9-methoxy-2,6...)
Show SMILES CO[C@@H](Cc1ccccc1)[C@@H](C)\C=C(/C)\C=C\[C@H](NC(C)=O)[C@H](C)C(=O)NCC(O)=O
Show InChI InChI=1S/C24H34N2O5/c1-16(13-17(2)22(31-5)14-20-9-7-6-8-10-20)11-12-21(26-19(4)27)18(3)24(30)25-15-23(28)29/h6-13,17-18,21-22H,14-15H2,1-5H3,(H,25,30)(H,26,27)(H,28,29)/b12-11+,16-13+/t17-,18-,21-,22-/m0/s1
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n/an/a 500n/an/an/an/an/an/a



University of California at Irvine

Curated by ChEMBL


Assay Description
Inhibitory concentration of the compound against protein phosphatase 2A (PP2A) using phosphorylase-a assay


Bioorg Med Chem Lett 13: 2907-11 (2003)

More data for this
Ligand-Target Pair
Serine/threonine protein phosphatase 2A, catalytic subunit, alpha isoform


(Bos taurus)
BDBM50135691
PNG
((R)-2-((4E,6E)-(2S,3S,8S,9S)-3-Acetylamino-9-metho...)
Show SMILES CO[C@@H](Cc1ccccc1)[C@@H](C)\C=C(/C)\C=C\[C@H](NC(C)=O)[C@H](C)C(=O)N[C@H](C)C(O)=O
Show InChI InChI=1S/C25H36N2O5/c1-16(14-17(2)23(32-6)15-21-10-8-7-9-11-21)12-13-22(27-20(5)28)18(3)24(29)26-19(4)25(30)31/h7-14,17-19,22-23H,15H2,1-6H3,(H,26,29)(H,27,28)(H,30,31)/b13-12+,16-14+/t17-,18-,19+,22-,23-/m0/s1
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n/an/a 7.00E+3n/an/an/an/an/an/a



University of California at Irvine

Curated by ChEMBL


Assay Description
Inhibitory concentration against protein phosphatase 2A (PP2A) using pNPP assay


Bioorg Med Chem Lett 13: 2907-11 (2003)

More data for this
Ligand-Target Pair
Serine/threonine protein phosphatase 2A, catalytic subunit, alpha isoform


(Bos taurus)
BDBM50135700
PNG
((S)-2-((4E,6E)-(2S,3S,8S,9S)-3-Acetylamino-9-metho...)
Show SMILES CO[C@@H](Cc1ccccc1)[C@@H](C)\C=C(/C)\C=C\[C@H](NC(C)=O)[C@H](C)C(=O)N[C@@H](C)C(O)=O
Show InChI InChI=1S/C25H36N2O5/c1-16(14-17(2)23(32-6)15-21-10-8-7-9-11-21)12-13-22(27-20(5)28)18(3)24(29)26-19(4)25(30)31/h7-14,17-19,22-23H,15H2,1-6H3,(H,26,29)(H,27,28)(H,30,31)/b13-12+,16-14+/t17-,18-,19-,22-,23-/m0/s1
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PubMed
n/an/a 7.80E+3n/an/an/an/an/an/a



University of California at Irvine

Curated by ChEMBL


Assay Description
Inhibitory concentration of the compound against protein phosphatase 2A (PP2A) using phosphorylase-a assay


Bioorg Med Chem Lett 13: 2907-11 (2003)

More data for this
Ligand-Target Pair
Serine/threonine protein phosphatase 2A, catalytic subunit, alpha isoform


(Bos taurus)
BDBM50135696
PNG
((2R,5S)-1-((4E,6E)-(2S,3S,8S,9S)-3-Acetylamino-9-m...)
Show SMILES CO[C@@H](Cc1ccccc1)[C@@H](C)\C=C(/C)\C=C\[C@H](NC(C)=O)[C@H](C)C(=O)N1[C@H](CC[C@H]1C(O)=O)C(O)=O
Show InChI InChI=1S/C28H38N2O7/c1-17(15-18(2)25(37-5)16-21-9-7-6-8-10-21)11-12-22(29-20(4)31)19(3)26(32)30-23(27(33)34)13-14-24(30)28(35)36/h6-12,15,18-19,22-25H,13-14,16H2,1-5H3,(H,29,31)(H,33,34)(H,35,36)/b12-11+,17-15+/t18-,19-,22-,23-,24+,25-/m0/s1
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n/an/a 1.00E+4n/an/an/an/an/an/a



University of California at Irvine

Curated by ChEMBL


Assay Description
Inhibitory concentration against protein phosphatase 2A (PP2A) using pNPP assay


Bioorg Med Chem Lett 13: 2907-11 (2003)

More data for this
Ligand-Target Pair
Serine/threonine protein phosphatase 2A, catalytic subunit, alpha isoform


(Bos taurus)
BDBM50135687
PNG
((R)-1-((4E,6E)-(2S,3S,8S,9S)-3-Acetylamino-9-metho...)
Show SMILES CO[C@@H](Cc1ccccc1)[C@@H](C)\C=C(/C)\C=C\[C@H](NC(C)=O)[C@H](C)C(=O)N1CCC[C@@H]1C(O)=O
Show InChI InChI=1S/C27H38N2O5/c1-18(16-19(2)25(34-5)17-22-10-7-6-8-11-22)13-14-23(28-21(4)30)20(3)26(31)29-15-9-12-24(29)27(32)33/h6-8,10-11,13-14,16,19-20,23-25H,9,12,15,17H2,1-5H3,(H,28,30)(H,32,33)/b14-13+,18-16+/t19-,20-,23-,24+,25-/m0/s1
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n/an/a>2.50E+4n/an/an/an/an/an/a



University of California at Irvine

Curated by ChEMBL


Assay Description
Inhibitory concentration against protein phosphatase 2A (PP2A) using pNPP assay


Bioorg Med Chem Lett 13: 2907-11 (2003)

More data for this
Ligand-Target Pair
Serine/threonine protein phosphatase 2A, catalytic subunit, alpha isoform


(Bos taurus)
BDBM50135685
PNG
((2S,5S)-1-((4E,6E)-(2S,3S,8S,9S)-3-Acetylamino-9-m...)
Show SMILES CO[C@@H](Cc1ccccc1)[C@@H](C)\C=C(/C)\C=C\[C@H](NC(C)=O)[C@H](C)C(=O)N1[C@@H](CC[C@H]1C(O)=O)C(O)=O
Show InChI InChI=1S/C28H38N2O7/c1-17(15-18(2)25(37-5)16-21-9-7-6-8-10-21)11-12-22(29-20(4)31)19(3)26(32)30-23(27(33)34)13-14-24(30)28(35)36/h6-12,15,18-19,22-25H,13-14,16H2,1-5H3,(H,29,31)(H,33,34)(H,35,36)/b12-11+,17-15+/t18-,19-,22-,23-,24-,25-/m0/s1
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n/an/a>3.90E+4n/an/an/an/an/an/a



University of California at Irvine

Curated by ChEMBL


Assay Description
Inhibitory concentration against protein phosphatase 2A (PP2A) using pNPP assay


Bioorg Med Chem Lett 13: 2907-11 (2003)

More data for this
Ligand-Target Pair
Serine/threonine protein phosphatase 2A, catalytic subunit, alpha isoform


(Bos taurus)
BDBM50135683
PNG
((2R,4R)-1-((4E,6E)-(2S,3S,8S,9S)-3-Acetylamino-9-m...)
Show SMILES CO[C@@H](Cc1ccccc1)[C@@H](C)\C=C(/C)\C=C\[C@H](NC(C)=O)[C@H](C)C(=O)N1C[C@@H](C[C@@H]1C(O)=O)O[Si](C(C)C)(C(C)C)C(C)C
Show InChI InChI=1S/C36H58N2O6Si/c1-23(2)45(24(3)4,25(5)6)44-31-21-33(36(41)42)38(22-31)35(40)28(9)32(37-29(10)39)18-17-26(7)19-27(8)34(43-11)20-30-15-13-12-14-16-30/h12-19,23-25,27-28,31-34H,20-22H2,1-11H3,(H,37,39)(H,41,42)/b18-17+,26-19+/t27-,28-,31+,32-,33+,34-/m0/s1
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n/an/a>6.30E+4n/an/an/an/an/an/a



University of California at Irvine

Curated by ChEMBL


Assay Description
Inhibitory concentration against protein phosphatase 2A (PP2A) using pNPP assay


Bioorg Med Chem Lett 13: 2907-11 (2003)

More data for this
Ligand-Target Pair
Serine/threonine protein phosphatase 2A, catalytic subunit, alpha isoform


(Bos taurus)
BDBM50135694
PNG
((S)-1-((4E,6E)-(2S,3S,8S,9S)-3-Acetylamino-9-metho...)
Show SMILES CO[C@@H](Cc1ccccc1)[C@@H](C)\C=C(/C)\C=C\[C@H](NC(C)=O)[C@H](C)C(=O)N1CCC[C@H]1C(=O)OC
Show InChI InChI=1S/C28H40N2O5/c1-19(17-20(2)26(34-5)18-23-11-8-7-9-12-23)14-15-24(29-22(4)31)21(3)27(32)30-16-10-13-25(30)28(33)35-6/h7-9,11-12,14-15,17,20-21,24-26H,10,13,16,18H2,1-6H3,(H,29,31)/b15-14+,19-17+/t20-,21-,24-,25-,26-/m0/s1
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n/an/a>1.00E+5n/an/an/an/an/an/a



University of California at Irvine

Curated by ChEMBL


Assay Description
Inhibitory concentration against protein phosphatase 2A (PP2A) using pNPP assay


Bioorg Med Chem Lett 13: 2907-11 (2003)

More data for this
Ligand-Target Pair
Serine/threonine protein phosphatase 2A, catalytic subunit, alpha isoform


(Bos taurus)
BDBM50135698
PNG
((R)-2-((4E,6E)-(2S,3S)-3-Acetylamino-2,6-dimethyl-...)
Show SMILES C[C@@H](NC(=O)[C@@H](C)[C@@H](NC(C)=O)\C=C\C(\C)=C\CCCc1ccccc1)C(O)=O
Show InChI InChI=1S/C23H32N2O4/c1-16(10-8-9-13-20-11-6-5-7-12-20)14-15-21(25-19(4)26)17(2)22(27)24-18(3)23(28)29/h5-7,10-12,14-15,17-18,21H,8-9,13H2,1-4H3,(H,24,27)(H,25,26)(H,28,29)/b15-14+,16-10+/t17-,18+,21-/m0/s1
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n/an/a>1.00E+5n/an/an/an/an/an/a



University of California at Irvine

Curated by ChEMBL


Assay Description
Inhibitory concentration against protein phosphatase 2A (PP2A) using pNPP assay


Bioorg Med Chem Lett 13: 2907-11 (2003)

More data for this
Ligand-Target Pair
Serine/threonine protein phosphatase 2A, catalytic subunit, alpha isoform


(Bos taurus)
BDBM50135682
PNG
((2S,4R)-1-((4E,6E)-(2S,3S,8S,9S)-3-Acetylamino-9-m...)
Show SMILES CO[C@@H](Cc1ccccc1)[C@@H](C)\C=C(/C)\C=C\[C@H](NC(C)=O)[C@H](C)C(=O)N1C[C@@H](C[C@H]1C(O)=O)C(O)=O
Show InChI InChI=1S/C28H38N2O7/c1-17(13-18(2)25(37-5)14-21-9-7-6-8-10-21)11-12-23(29-20(4)31)19(3)26(32)30-16-22(27(33)34)15-24(30)28(35)36/h6-13,18-19,22-25H,14-16H2,1-5H3,(H,29,31)(H,33,34)(H,35,36)/b12-11+,17-13+/t18-,19-,22+,23-,24-,25-/m0/s1
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n/an/a>1.00E+5n/an/an/an/an/an/a



University of California at Irvine

Curated by ChEMBL


Assay Description
Inhibitory concentration against protein phosphatase 2A (PP2A) using pNPP assay


Bioorg Med Chem Lett 13: 2907-11 (2003)

More data for this
Ligand-Target Pair
Serine/threonine protein phosphatase 2A, catalytic subunit, alpha isoform


(Bos taurus)
BDBM50135684
PNG
((S)-1-((4E,6E)-(2S,3S,8S,9S)-3-Acetylamino-9-metho...)
Show SMILES CO[C@@H](Cc1ccccc1)[C@@H](C)\C=C(/C)\C=C\[C@H](NC(C)=O)[C@H](C)C(=O)N1CCC[C@H]1C(O)=O
Show InChI InChI=1S/C27H38N2O5/c1-18(16-19(2)25(34-5)17-22-10-7-6-8-11-22)13-14-23(28-21(4)30)20(3)26(31)29-15-9-12-24(29)27(32)33/h6-8,10-11,13-14,16,19-20,23-25H,9,12,15,17H2,1-5H3,(H,28,30)(H,32,33)/b14-13+,18-16+/t19-,20-,23-,24-,25-/m0/s1
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n/an/a>1.00E+5n/an/an/an/an/an/a



University of California at Irvine

Curated by ChEMBL


Assay Description
Inhibitory concentration against protein phosphatase 2A (PP2A) using pNPP assay


Bioorg Med Chem Lett 13: 2907-11 (2003)

More data for this
Ligand-Target Pair
Serine/threonine protein phosphatase 2A, catalytic subunit, alpha isoform


(Bos taurus)
BDBM50135693
PNG
((2R,4S)-1-((4E,6E)-(2S,3S,8S,9S)-3-Acetylamino-9-m...)
Show SMILES CO[C@@H](Cc1ccccc1)[C@@H](C)\C=C(/C)\C=C\[C@H](NC(C)=O)[C@H](C)C(=O)N1C[C@H](C[C@@H]1C(O)=O)C(O)=O
Show InChI InChI=1S/C28H38N2O7/c1-17(13-18(2)25(37-5)14-21-9-7-6-8-10-21)11-12-23(29-20(4)31)19(3)26(32)30-16-22(27(33)34)15-24(30)28(35)36/h6-13,18-19,22-25H,14-16H2,1-5H3,(H,29,31)(H,33,34)(H,35,36)/b12-11+,17-13+/t18-,19-,22-,23-,24+,25-/m0/s1
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n/an/a>1.00E+5n/an/an/an/an/an/a



University of California at Irvine

Curated by ChEMBL


Assay Description
Inhibitory concentration against protein phosphatase 2A (PP2A) using pNPP assay


Bioorg Med Chem Lett 13: 2907-11 (2003)

More data for this
Ligand-Target Pair
Serine/threonine protein phosphatase 2A, catalytic subunit, alpha isoform


(Bos taurus)
BDBM50135695
PNG
((R)-2-[(4E,6E)-(2S,3S)-3-Acetylamino-7-(2-benzyl-p...)
Show SMILES C[C@@H](NC(=O)[C@@H](C)[C@@H](NC(C)=O)\C=C\C(\C)=C\c1ccccc1Cc1ccccc1)C(O)=O
Show InChI InChI=1S/C27H32N2O4/c1-18(16-23-12-8-9-13-24(23)17-22-10-6-5-7-11-22)14-15-25(29-21(4)30)19(2)26(31)28-20(3)27(32)33/h5-16,19-20,25H,17H2,1-4H3,(H,28,31)(H,29,30)(H,32,33)/b15-14+,18-16+/t19-,20+,25-/m0/s1
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n/an/a>1.00E+5n/an/an/an/an/an/a



University of California at Irvine

Curated by ChEMBL


Assay Description
Inhibitory concentration against protein phosphatase 2A (PP2A) using pNPP assay


Bioorg Med Chem Lett 13: 2907-11 (2003)

More data for this
Ligand-Target Pair
Serine/threonine protein phosphatase 2A, catalytic subunit, alpha isoform


(Bos taurus)
BDBM50135692
PNG
(CHEMBL100880 | N-[(2E,4E)-(1S,6S,7S)-7-Methoxy-4,6...)
Show SMILES CO[C@@H](Cc1ccccc1)[C@@H](C)\C=C(/C)\C=C\[C@H](NC(C)=O)[C@H](C)C(=O)N1CCCC1
Show InChI InChI=1S/C26H38N2O3/c1-19(17-20(2)25(31-5)18-23-11-7-6-8-12-23)13-14-24(27-22(4)29)21(3)26(30)28-15-9-10-16-28/h6-8,11-14,17,20-21,24-25H,9-10,15-16,18H2,1-5H3,(H,27,29)/b14-13+,19-17+/t20-,21-,24-,25-/m0/s1
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n/an/a>1.00E+5n/an/an/an/an/an/a



University of California at Irvine

Curated by ChEMBL


Assay Description
Inhibitory concentration against protein phosphatase 2A (PP2A) using pNPP assay


Bioorg Med Chem Lett 13: 2907-11 (2003)

More data for this
Ligand-Target Pair
Serine/threonine protein phosphatase 2A, catalytic subunit, alpha isoform


(Bos taurus)
BDBM50135690
PNG
(CHEMBL98661 | [((4E,6E)-(2S,3S,8S,9S)-3-Acetylamin...)
Show SMILES CO[C@@H](Cc1ccccc1)[C@@H](C)\C=C(/C)\C=C\[C@H](NC(C)=O)[C@H](C)C(=O)N(CC(O)=O)CC(O)=O
Show InChI InChI=1S/C26H36N2O7/c1-17(13-18(2)23(35-5)14-21-9-7-6-8-10-21)11-12-22(27-20(4)29)19(3)26(34)28(15-24(30)31)16-25(32)33/h6-13,18-19,22-23H,14-16H2,1-5H3,(H,27,29)(H,30,31)(H,32,33)/b12-11+,17-13+/t18-,19-,22-,23-/m0/s1
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n/an/a>1.00E+5n/an/an/an/an/an/a



University of California at Irvine

Curated by ChEMBL


Assay Description
Inhibitory concentration against protein phosphatase 2A (PP2A) using pNPP assay


Bioorg Med Chem Lett 13: 2907-11 (2003)

More data for this
Ligand-Target Pair
Serine/threonine protein phosphatase 2A, catalytic subunit, alpha isoform


(Bos taurus)
BDBM50135688
PNG
((R)-1-((4E,6E)-(2S,3S,8S,9S)-3-Acetylamino-9-metho...)
Show SMILES CO[C@@H](Cc1ccccc1)[C@@H](C)\C=C(/C)\C=C\[C@H](NC(C)=O)[C@H](C)C(=O)N1CCC[C@@H]1C(=O)OC
Show InChI InChI=1S/C28H40N2O5/c1-19(17-20(2)26(34-5)18-23-11-8-7-9-12-23)14-15-24(29-22(4)31)21(3)27(32)30-16-10-13-25(30)28(33)35-6/h7-9,11-12,14-15,17,20-21,24-26H,10,13,16,18H2,1-6H3,(H,29,31)/b15-14+,19-17+/t20-,21-,24-,25+,26-/m0/s1
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University of California at Irvine

Curated by ChEMBL


Assay Description
Inhibitory concentration against protein phosphatase 2A (PP2A) using pNPP assay


Bioorg Med Chem Lett 13: 2907-11 (2003)

More data for this
Ligand-Target Pair
Serine/threonine protein phosphatase 2A, catalytic subunit, alpha isoform


(Bos taurus)
BDBM50135689
PNG
((2R,4R)-1-((4E,6E)-(2S,3S,8S,9S)-3-Acetylamino-9-m...)
Show SMILES CO[C@@H](Cc1ccccc1)[C@@H](C)\C=C(/C)\C=C\[C@H](NC(C)=O)[C@H](C)C(=O)N1C[C@@H](C[C@@H]1C(O)=O)C(O)=O
Show InChI InChI=1S/C28H38N2O7/c1-17(13-18(2)25(37-5)14-21-9-7-6-8-10-21)11-12-23(29-20(4)31)19(3)26(32)30-16-22(27(33)34)15-24(30)28(35)36/h6-13,18-19,22-25H,14-16H2,1-5H3,(H,29,31)(H,33,34)(H,35,36)/b12-11+,17-13+/t18-,19-,22+,23-,24+,25-/m0/s1
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University of California at Irvine

Curated by ChEMBL


Assay Description
Inhibitory concentration against protein phosphatase 2A (PP2A) using pNPP assay


Bioorg Med Chem Lett 13: 2907-11 (2003)

More data for this
Ligand-Target Pair
Serine/threonine protein phosphatase 2A, catalytic subunit, alpha isoform


(Bos taurus)
BDBM50135686
PNG
((R)-2-((4E,6E)-(2S,3S)-3-Acetylamino-7-biphenyl-4-...)
Show SMILES C[C@@H](NC(=O)[C@@H](C)[C@@H](NC(C)=O)\C=C\C(\C)=C\c1ccc(cc1)-c1ccccc1)C(O)=O
Show InChI InChI=1S/C26H30N2O4/c1-17(16-21-11-13-23(14-12-21)22-8-6-5-7-9-22)10-15-24(28-20(4)29)18(2)25(30)27-19(3)26(31)32/h5-16,18-19,24H,1-4H3,(H,27,30)(H,28,29)(H,31,32)/b15-10+,17-16+/t18-,19+,24-/m0/s1
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n/an/a>1.00E+5n/an/an/an/an/an/a



University of California at Irvine

Curated by ChEMBL


Assay Description
Inhibitory concentration against protein phosphatase 2A (PP2A) using pNPP assay


Bioorg Med Chem Lett 13: 2907-11 (2003)

More data for this
Ligand-Target Pair