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Compile Data Set for Download or QSAR

Found 21 hits Enz. Inhib. hit(s) with Target = 'Serine racemase' AND taxid = 10090   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serine racemase


(Mus musculus)
BDBM50038343
PNG
(CHEMBL3360546)
Show SMILES [Na+].[Na+].[O-]C(=O)C(Cl)(Cl)C([O-])=O
Show InChI InChI=1S/C3H2Cl2O4.2Na/c4-3(5,1(6)7)2(8)9;;/h(H,6,7)(H,8,9);;/q;2*+1/p-2
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1.90E+4n/an/an/an/an/an/an/an/a



Academy of Sciences of the Czech Republic

Curated by ChEMBL


Assay Description
Inhibition of mouse serine racemase by Lineweaver-Burk plot


Citation and Details
More data for this
Ligand-Target Pair
Serine racemase


(Mus musculus)
BDBM14673
PNG
(Fragment 3 | Malonic Acid | propanedioic acid)
Show SMILES OC(=O)CC(O)=O
Show InChI InChI=1S/C3H4O4/c4-2(5)1-3(6)7/h1H2,(H,4,5)(H,6,7)
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2.70E+4n/an/an/an/an/an/an/an/a



Academy of Sciences of the Czech Republic

Curated by ChEMBL


Assay Description
Inhibition of mouse serine racemase by Lineweaver-Burk plot


Citation and Details
More data for this
Ligand-Target Pair
Serine racemase


(Mus musculus)
BDBM50378533
PNG
(CHEMBL568192)
Show SMILES N[C@H]([C@H](O)C(O)=O)C(O)=O
Show InChI InChI=1S/C4H7NO5/c5-1(3(7)8)2(6)4(9)10/h1-2,6H,5H2,(H,7,8)(H,9,10)/t1-,2+/m1/s1
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4.30E+4n/an/an/an/an/an/an/an/a



Institute of Organic Chemistry and Biochemistry of the ASCR

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant serine racemase transfected in bacterial expression system


Citation and Details
More data for this
Ligand-Target Pair
Serine racemase


(Mus musculus)
BDBM14673
PNG
(Fragment 3 | Malonic Acid | propanedioic acid)
Show SMILES OC(=O)CC(O)=O
Show InChI InChI=1S/C3H4O4/c4-2(5)1-3(6)7/h1H2,(H,4,5)(H,6,7)
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7.10E+4n/an/an/an/an/an/an/an/a



Institute of Organic Chemistry and Biochemistry of the ASCR

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant serine racemase transfected in bacterial expression system


Citation and Details
More data for this
Ligand-Target Pair
Serine racemase


(Mus musculus)
BDBM50378532
PNG
(CHEMBL569435)
Show SMILES ONC(=O)CC(=O)NO
Show InChI InChI=1S/C3H6N2O4/c6-2(4-8)1-3(7)5-9/h8-9H,1H2,(H,4,6)(H,5,7)
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4.17E+5n/an/an/an/an/an/an/an/a



Institute of Organic Chemistry and Biochemistry of the ASCR

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant serine racemase expressed in Escherichia coli MC1061 assessed as formation of D-serine after 30 mins by Linewaver-bur...


Citation and Details
More data for this
Ligand-Target Pair
Serine racemase


(Mus musculus)
BDBM50378534
PNG
(CHEMBL216796)
Show SMILES NCC(=O)NO
Show InChI InChI=1S/C2H6N2O2/c3-1-2(5)4-6/h6H,1,3H2,(H,4,5)
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1.64E+6n/an/an/an/an/an/an/an/a



Institute of Organic Chemistry and Biochemistry of the ASCR

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant serine racemase transfected in bacterial expression system


Citation and Details
More data for this
Ligand-Target Pair
Serine racemase


(Mus musculus)
BDBM50129194
PNG
((2S)-2-amino-4-(hydroxyamino)-4-oxobutanoic acidN(...)
Show SMILES N[C@@H](CC(=O)NO)C(O)=O
Show InChI InChI=1S/C4H8N2O4/c5-2(4(8)9)1-3(7)6-10/h2,10H,1,5H2,(H,6,7)(H,8,9)/t2-/m0/s1
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1.90E+6n/an/an/an/an/an/an/an/a



Institute of Organic Chemistry and Biochemistry of the ASCR

Curated by ChEMBL


Assay Description
Inhibition of mouse brain serine racemase


Citation and Details
More data for this
Ligand-Target Pair
Serine racemase


(Mus musculus)
BDBM50038343
PNG
(CHEMBL3360546)
Show SMILES [Na+].[Na+].[O-]C(=O)C(Cl)(Cl)C([O-])=O
Show InChI InChI=1S/C3H2Cl2O4.2Na/c4-3(5,1(6)7)2(8)9;;/h(H,6,7)(H,8,9);;/q;2*+1/p-2
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n/an/a 5.70E+4n/an/an/an/an/an/a



Academy of Sciences of the Czech Republic

Curated by ChEMBL


Assay Description
Inhibition of mouse serine racemase using L-serine substrate by reversed-phase HPLC analysis


Citation and Details
More data for this
Ligand-Target Pair
Serine racemase


(Mus musculus)
BDBM14673
PNG
(Fragment 3 | Malonic Acid | propanedioic acid)
Show SMILES OC(=O)CC(O)=O
Show InChI InChI=1S/C3H4O4/c4-2(5)1-3(6)7/h1H2,(H,4,5)(H,6,7)
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n/an/a 6.70E+4n/an/an/an/an/an/a



Academy of Sciences of the Czech Republic

Curated by ChEMBL


Assay Description
Inhibition of mouse serine racemase using L-serine substrate by reversed-phase HPLC analysis


Citation and Details
More data for this
Ligand-Target Pair
Serine racemase


(Mus musculus)
BDBM50378531
PNG
(CHEMBL566071)
Show SMILES ONC(=O)CCC(=O)NO
Show InChI InChI=1S/C4H8N2O4/c7-3(5-9)1-2-4(8)6-10/h9-10H,1-2H2,(H,5,7)(H,6,8)
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n/an/a 9.00E+4n/an/an/an/an/an/a



Institute of Organic Chemistry and Biochemistry of the ASCR

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant serine racemase expressed in Escherichia coli MC1061 assessed as formation of D-serine after 30 mins by HPLC analysis


Citation and Details
More data for this
Ligand-Target Pair
Serine racemase


(Mus musculus)
BDBM50038354
PNG
(CHEBI:16513 | CHEMBL1794676)
Show SMILES OC(C(O)=O)C(O)=O
Show InChI InChI=1S/C3H4O5/c4-1(2(5)6)3(7)8/h1,4H,(H,5,6)(H,7,8)
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n/an/a 9.40E+4n/an/an/an/an/an/a



Academy of Sciences of the Czech Republic

Curated by ChEMBL


Assay Description
Inhibition of mouse serine racemase using L-serine substrate by reversed-phase HPLC analysis


Citation and Details
More data for this
Ligand-Target Pair
Serine racemase


(Mus musculus)
BDBM50378530
PNG
(CHEMBL566494)
Show SMILES ONC(=O)CCCC(=O)NO
Show InChI InChI=1S/C5H10N2O4/c8-4(6-10)2-1-3-5(9)7-11/h10-11H,1-3H2,(H,6,8)(H,7,9)
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n/an/a 1.70E+5n/an/an/an/an/an/a



Institute of Organic Chemistry and Biochemistry of the ASCR

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant serine racemase expressed in Escherichia coli MC1061 assessed as formation of D-serine after 30 mins by HPLC analysis


Citation and Details
More data for this
Ligand-Target Pair
Serine racemase


(Mus musculus)
BDBM50378532
PNG
(CHEMBL569435)
Show SMILES ONC(=O)CC(=O)NO
Show InChI InChI=1S/C3H6N2O4/c6-2(4-8)1-3(7)5-9/h8-9H,1H2,(H,4,6)(H,5,7)
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n/an/a 3.70E+5n/an/an/an/an/an/a



Institute of Organic Chemistry and Biochemistry of the ASCR

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant serine racemase expressed in Escherichia coli MC1061 assessed as formation of D-serine after 30 mins by HPLC analysis


Citation and Details
More data for this
Ligand-Target Pair
Serine racemase


(Mus musculus)
BDBM92990
PNG
(Aminomalonate)
Show SMILES NC(C([O-])=O)C([O-])=O
Show InChI InChI=1S/C3H5NO4/c4-1(2(5)6)3(7)8/h1H,4H2,(H,5,6)(H,7,8)/p-2
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n/an/a 4.00E+5n/an/an/an/an/an/a



Academy of Sciences of the Czech Republic

Curated by ChEMBL


Assay Description
Inhibition of mouse serine racemase using L-serine substrate by reversed-phase HPLC analysis


Citation and Details
More data for this
Ligand-Target Pair
Serine racemase


(Mus musculus)
BDBM50038342
PNG
(CHEMBL3360547)
Show SMILES [Na+].[Na+].[O-]C(=O)C(Cl)C([O-])=O
Show InChI InChI=1S/C3H3ClO4.2Na/c4-1(2(5)6)3(7)8;;/h1H,(H,5,6)(H,7,8);;/q;2*+1/p-2
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n/an/a 7.80E+5n/an/an/an/an/an/a



Academy of Sciences of the Czech Republic

Curated by ChEMBL


Assay Description
Inhibition of mouse serine racemase using L-serine substrate by reversed-phase HPLC analysis


Citation and Details
More data for this
Ligand-Target Pair
Serine racemase


(Mus musculus)
BDBM50129194
PNG
((2S)-2-amino-4-(hydroxyamino)-4-oxobutanoic acidN(...)
Show SMILES N[C@@H](CC(=O)NO)C(O)=O
Show InChI InChI=1S/C4H8N2O4/c5-2(4(8)9)1-3(7)6-10/h2,10H,1,5H2,(H,6,7)(H,8,9)/t2-/m0/s1
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n/an/a 1.30E+6n/an/an/an/an/an/a



Institute of Organic Chemistry and Biochemistry of the ASCR

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant serine racemase expressed in Escherichia coli MC1061 assessed as formation of D-serine after 30 mins by HPLC analysis


Citation and Details
More data for this
Ligand-Target Pair
Serine racemase


(Mus musculus)
BDBM50038341
PNG
(CHEBI:30860 | METHYLMALONIC ACID)
Show SMILES CC(C(O)=O)C(O)=O
Show InChI InChI=1S/C4H6O4/c1-2(3(5)6)4(7)8/h2H,1H3,(H,5,6)(H,7,8)
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n/an/a 1.85E+6n/an/an/an/an/an/a



Academy of Sciences of the Czech Republic

Curated by ChEMBL


Assay Description
Inhibition of mouse serine racemase using L-serine substrate by reversed-phase HPLC analysis


Citation and Details
More data for this
Ligand-Target Pair
Serine racemase


(Mus musculus)
BDBM50038340
PNG
(CHEMBL3360548)
Show SMILES [Na+].[Na+].[O-]C(=O)C(F)(F)C([O-])=O
Show InChI InChI=1S/C3H2F2O4.2Na/c4-3(5,1(6)7)2(8)9;;/h(H,6,7)(H,8,9);;/q;2*+1/p-2
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n/an/a 2.16E+6n/an/an/an/an/an/a



Academy of Sciences of the Czech Republic

Curated by ChEMBL


Assay Description
Inhibition of mouse serine racemase using L-serine substrate by reversed-phase HPLC analysis


Citation and Details
More data for this
Ligand-Target Pair
Serine racemase


(Mus musculus)
BDBM50038339
PNG
(CHEMBL3360549)
Show SMILES CC(C)(C(O)=O)C(O)=O
Show InChI InChI=1S/C5H8O4/c1-5(2,3(6)7)4(8)9/h1-2H3,(H,6,7)(H,8,9)
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n/an/a 5.63E+6n/an/an/an/an/an/a



Academy of Sciences of the Czech Republic

Curated by ChEMBL


Assay Description
Inhibition of mouse serine racemase using L-serine substrate by reversed-phase HPLC analysis


Citation and Details
More data for this
Ligand-Target Pair
Serine racemase


(Mus musculus)
BDBM50038338
PNG
(CHEMBL3360550)
Show SMILES OC(=O)C(C(O)=O)c1ccsc1
Show InChI InChI=1S/C7H6O4S/c8-6(9)5(7(10)11)4-1-2-12-3-4/h1-3,5H,(H,8,9)(H,10,11)
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n/an/a 7.03E+6n/an/an/an/an/an/a



Academy of Sciences of the Czech Republic

Curated by ChEMBL


Assay Description
Inhibition of mouse serine racemase using L-serine substrate by reversed-phase HPLC analysis


Citation and Details
More data for this
Ligand-Target Pair
Serine racemase


(Mus musculus)
BDBM50038355
PNG
(CHEMBL3360551)
Show SMILES [Na+].[Na+].OCC(CO)(C([O-])=O)C([O-])=O
Show InChI InChI=1S/C5H8O6.2Na/c6-1-5(2-7,3(8)9)4(10)11;;/h6-7H,1-2H2,(H,8,9)(H,10,11);;/q;2*+1/p-2
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n/an/a 4.06E+7n/an/an/an/an/an/a



Academy of Sciences of the Czech Republic

Curated by ChEMBL


Assay Description
Inhibition of mouse serine racemase using L-serine substrate by reversed-phase HPLC analysis


Citation and Details
More data for this
Ligand-Target Pair