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Compile Data Set for Download or QSAR

Found 33 hits Enz. Inhib. hit(s) with Target = 'Serotonin transporter' AND taxid = 10090   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serotonin transporter


(Mus musculus)
BDBM50308250
PNG
((1R,5R,6R)-1-(3,4-dichlorophenyl)-6-(ethoxymethyl)...)
Show SMILES CCOC[C@@H]1[C@H]2CNC[C@@]12c1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C14H17Cl2NO/c1-2-18-7-11-10-6-17-8-14(10,11)9-3-4-12(15)13(16)5-9/h3-5,10-11,17H,2,6-8H2,1H3/t10-,11-,14+/m1/s1
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0.851n/an/an/an/an/an/an/an/a



GlaxoSmithKline Medicine Research Centre

Curated by ChEMBL


Assay Description
Displacement of [3H]citalopram from mouse cortex SERT by filtration binding assay


Citation and Details
More data for this
Ligand-Target Pair
Serotonin transporter


(Mus musculus)
BDBM50322698
PNG
(rel-1-(3,4-dichlorophenyl)-6-(methoxymethyl)-3-aza...)
Show SMILES COC[C@]12C[C@]1(CCNC2)c1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C14H17Cl2NO/c1-18-9-13-7-14(13,4-5-17-8-13)10-2-3-11(15)12(16)6-10/h2-3,6,17H,4-5,7-9H2,1H3/t13-,14-/m1/s1
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1.58n/an/an/an/an/an/an/an/a



GlaxoSmithKline Medicines Research Centre

Curated by ChEMBL


Assay Description
Displacement of [3H]-citalopram from SERT in mouse cortex after 2 hrs by liquid scintillation counting


Citation and Details
More data for this
Ligand-Target Pair
Serotonin transporter


(Mus musculus)
BDBM50010859
PNG
(CHEMBL11 | IMIPRAMINE HYDROCHLORIDE | IMIPRAMINE P...)
Show SMILES CN(C)CCCN1c2ccccc2CCc2ccccc12
Show InChI InChI=1S/C19H24N2/c1-20(2)14-7-15-21-18-10-5-3-8-16(18)12-13-17-9-4-6-11-19(17)21/h3-6,8-11H,7,12-15H2,1-2H3
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5n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity to Serotonin transporter using [3H]-paroxetine as radioligand in stably transfected NIH3T3 cells


Bioorg Med Chem Lett 11: 655-8 (2001)

More data for this
Ligand-Target Pair
Serotonin transporter


(Mus musculus)
BDBM22165
PNG
(1-{2-[bis(4-fluorophenyl)methoxy]ethyl}-4-(3-pheny...)
Show SMILES Fc1ccc(cc1)C(OCCN1CCN(CCCc2ccccc2)CC1)c1ccc(F)cc1
Show InChI InChI=1S/C28H32F2N2O/c29-26-12-8-24(9-13-26)28(25-10-14-27(30)15-11-25)33-22-21-32-19-17-31(18-20-32)16-4-7-23-5-2-1-3-6-23/h1-3,5-6,8-15,28H,4,7,16-22H2
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24n/an/an/an/an/an/an/an/a



University of Missouri

Curated by ChEMBL


Assay Description
Displacement of [3H]paroxetine from mouse SERT in whole brain membrane


Citation and Details
More data for this
Ligand-Target Pair
Serotonin transporter


(Mus musculus)
BDBM50040252
PNG
(CHEMBL3360020)
Show SMILES CCCOc1ccc(CCN2CCN(CCCc3ccccc3)CC2)cc1OC
Show InChI InChI=1S/C25H36N2O2/c1-3-20-29-24-12-11-23(21-25(24)28-2)13-15-27-18-16-26(17-19-27)14-7-10-22-8-5-4-6-9-22/h4-6,8-9,11-12,21H,3,7,10,13-20H2,1-2H3
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124n/an/an/an/an/an/an/an/a



University of Missouri

Curated by ChEMBL


Assay Description
Displacement of [3H]paroxetine from mouse SERT in whole brain membrane


Citation and Details
More data for this
Ligand-Target Pair
Serotonin transporter


(Mus musculus)
BDBM50040255
PNG
(CHEMBL3360023)
Show SMILES COc1cc(CCN2CCN(CCCc3ccccc3)CC2)ccc1OCc1ccccc1
Show InChI InChI=1S/C29H36N2O2/c1-32-29-23-26(14-15-28(29)33-24-27-11-6-3-7-12-27)16-18-31-21-19-30(20-22-31)17-8-13-25-9-4-2-5-10-25/h2-7,9-12,14-15,23H,8,13,16-22,24H2,1H3
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128n/an/an/an/an/an/an/an/a



University of Missouri

Curated by ChEMBL


Assay Description
Displacement of [3H]paroxetine from mouse SERT in whole brain membrane


Citation and Details
More data for this
Ligand-Target Pair
Serotonin transporter


(Mus musculus)
BDBM50040251
PNG
(CHEMBL3360018)
Show SMILES COc1cc(CCN2CCN(CCCc3ccccc3)CC2)ccc1OC\C=C\I
Show InChI InChI=1S/C25H33IN2O2/c1-29-25-21-23(10-11-24(25)30-20-6-13-26)12-15-28-18-16-27(17-19-28)14-5-9-22-7-3-2-4-8-22/h2-4,6-8,10-11,13,21H,5,9,12,14-20H2,1H3/b13-6+
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174n/an/an/an/an/an/an/an/a



University of Missouri

Curated by ChEMBL


Assay Description
Displacement of [3H]paroxetine from mouse SERT in whole brain membrane


Citation and Details
More data for this
Ligand-Target Pair
Serotonin transporter


(Mus musculus)
BDBM50040254
PNG
(CHEMBL3360022)
Show SMILES COc1cc(CCN2CCN(CCCc3ccccc3)CC2)ccc1OCC=C
Show InChI InChI=1S/C25H34N2O2/c1-3-20-29-24-12-11-23(21-25(24)28-2)13-15-27-18-16-26(17-19-27)14-7-10-22-8-5-4-6-9-22/h3-6,8-9,11-12,21H,1,7,10,13-20H2,2H3
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295n/an/an/an/an/an/an/an/a



University of Missouri

Curated by ChEMBL


Assay Description
Displacement of [3H]paroxetine from mouse SERT in whole brain membrane


Citation and Details
More data for this
Ligand-Target Pair
Serotonin transporter


(Mus musculus)
BDBM50040256
PNG
(CHEMBL3352893)
Show SMILES C(CN1CCN(CCc2ccc3OCOc3c2)CC1)Cc1ccccc1
Show InChI InChI=1S/C22H28N2O2/c1-2-5-19(6-3-1)7-4-11-23-13-15-24(16-14-23)12-10-20-8-9-21-22(17-20)26-18-25-21/h1-3,5-6,8-9,17H,4,7,10-16,18H2
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468n/an/an/an/an/an/an/an/a



University of Missouri

Curated by ChEMBL


Assay Description
Displacement of [3H]paroxetine from mouse SERT in whole brain membrane


Citation and Details
More data for this
Ligand-Target Pair
Serotonin transporter


(Mus musculus)
BDBM50338990
PNG
(1-(3,4-dimethoxyphenethyl)-4-(3-phenylpropyl)piper...)
Show SMILES COc1ccc(CCN2CCN(CCCc3ccccc3)CC2)cc1OC
Show InChI InChI=1S/C23H32N2O2/c1-26-22-11-10-21(19-23(22)27-2)12-14-25-17-15-24(16-18-25)13-6-9-20-7-4-3-5-8-20/h3-5,7-8,10-11,19H,6,9,12-18H2,1-2H3
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760n/an/an/an/an/an/an/an/a



University of Missouri

Curated by ChEMBL


Assay Description
Displacement of [3H]paroxetine from mouse SERT in whole brain membrane


Citation and Details
More data for this
Ligand-Target Pair
Serotonin transporter


(Mus musculus)
BDBM50068454
PNG
(1-[2-(3-Methoxy-phenyl)-ethyl]-4-(3-phenyl-propyl)...)
Show SMILES COc1cccc(CCN2CCN(CCCc3ccccc3)CC2)c1
Show InChI InChI=1S/C22H30N2O/c1-25-22-11-5-9-21(19-22)12-14-24-17-15-23(16-18-24)13-6-10-20-7-3-2-4-8-20/h2-5,7-9,11,19H,6,10,12-18H2,1H3
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985n/an/an/an/an/an/an/an/a



University of Missouri

Curated by ChEMBL


Assay Description
Displacement of [3H]paroxetine from mouse SERT in whole brain membrane


Citation and Details
More data for this
Ligand-Target Pair
Serotonin transporter


(Mus musculus)
BDBM50068459
PNG
(1-[2-(4-Methoxy-phenyl)-ethyl]-4-(3-phenyl-propyl)...)
Show SMILES COc1ccc(CCN2CCN(CCCc3ccccc3)CC2)cc1
Show InChI InChI=1S/C22H30N2O/c1-25-22-11-9-21(10-12-22)13-15-24-18-16-23(17-19-24)14-5-8-20-6-3-2-4-7-20/h2-4,6-7,9-12H,5,8,13-19H2,1H3
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1.73E+3n/an/an/an/an/an/an/an/a



University of Missouri

Curated by ChEMBL


Assay Description
Displacement of [3H]paroxetine from mouse SERT in whole brain membrane


Citation and Details
More data for this
Ligand-Target Pair
Serotonin transporter


(Mus musculus)
BDBM50068452
PNG
(1-[2-(3,4-Dichloro-phenyl)-ethyl]-4-(3-phenyl-prop...)
Show SMILES Clc1ccc(CCN2CCN(CCCc3ccccc3)CC2)cc1Cl
Show InChI InChI=1S/C21H26Cl2N2/c22-20-9-8-19(17-21(20)23)10-12-25-15-13-24(14-16-25)11-4-7-18-5-2-1-3-6-18/h1-3,5-6,8-9,17H,4,7,10-16H2
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2.87E+3n/an/an/an/an/an/an/an/a



University of Missouri

Curated by ChEMBL


Assay Description
Displacement of [3H]paroxetine from mouse SERT in whole brain membrane


Citation and Details
More data for this
Ligand-Target Pair
Serotonin transporter


(Mus musculus)
BDBM50017721
PNG
(1-Methyl-4-(5H-dibenzo(a,d)cycloheptenylidene)pipe...)
Show SMILES CN1CCC(CC1)=C1c2ccccc2C=Cc2ccccc12
Show InChI InChI=1S/C21H21N/c1-22-14-12-18(13-15-22)21-19-8-4-2-6-16(19)10-11-17-7-3-5-9-20(17)21/h2-11H,12-15H2,1H3
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4.10E+3n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity to Serotonin transporter using [3H]-paroxetine as radioligand in stably transfected NIH3T3 cells


Bioorg Med Chem Lett 11: 655-8 (2001)

More data for this
Ligand-Target Pair
Serotonin transporter


(Mus musculus)
BDBM35920
PNG
(9,10-dihydroanthracene(DHA), 1a | 9-(Aminomethyl)-...)
Show SMILES NCC1c2ccccc2Cc2ccccc12
Show InChI InChI=1S/C15H15N/c16-10-15-13-7-3-1-5-11(13)9-12-6-2-4-8-14(12)15/h1-8,15H,9-10,16H2
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>1.00E+4n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity to Serotonin transporter using [3H]-paroxetine as radioligand in stably transfected NIH3T3 cells


Bioorg Med Chem Lett 11: 655-8 (2001)

More data for this
Ligand-Target Pair
Serotonin transporter


(Mus musculus)
BDBM77970
PNG
(3-(2-chloranyl-5,6-dihydrobenzo[b][1]benzazepin-11...)
Show SMILES CN(C)CCCN1c2ccccc2CCc2ccc(Cl)cc12
Show InChI InChI=1S/C19H23ClN2/c1-21(2)12-5-13-22-18-7-4-3-6-15(18)8-9-16-10-11-17(20)14-19(16)22/h3-4,6-7,10-11,14H,5,8-9,12-13H2,1-2H3
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n/an/a 70n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of 5-HT transporter in NMRI albino mouse brain assessed as [3H]5-HT accumulation in hypothalamus after 5 mins


J Med Chem 21: 78-82 (1978)

More data for this
Ligand-Target Pair
Serotonin transporter


(Mus musculus)
BDBM50010307
PNG
(CHEMBL3251303)
Show SMILES Cl.CN(C)C1CC(C1)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C18H21N.ClH/c1-19(2)17-13-18(14-17,15-9-5-3-6-10-15)16-11-7-4-8-12-16;/h3-12,17H,13-14H2,1-2H3;1H
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n/an/a 900n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of 5-HT transporter in NMRI albino mouse brain assessed as [3H]5-HT accumulation in hypothalamus after 5 mins


J Med Chem 21: 78-82 (1978)

More data for this
Ligand-Target Pair
Serotonin transporter


(Mus musculus)
BDBM50039246
PNG
((S)-1-(2-(tris(4-methoxyphenyl)methoxy)ethyl)piper...)
Show SMILES COc1ccc(cc1)C(OCCN1CCC[C@@H](C1)C(O)=O)(c1ccc(OC)cc1)c1ccc(OC)cc1
Show InChI InChI=1S/C30H35NO6/c1-34-26-12-6-23(7-13-26)30(24-8-14-27(35-2)15-9-24,25-10-16-28(36-3)17-11-25)37-20-19-31-18-4-5-22(21-31)29(32)33/h6-17,22H,4-5,18-21H2,1-3H3,(H,32,33)/t22-/m0/s1
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n/an/a 1.55E+3n/an/an/an/an/an/a



Ludwig-Maximilians-Universit£t M£nchen

Curated by ChEMBL


Assay Description
Inhibition of mouse GAT4 expressed in HEK293 cells by [3H]GABA uptake assay


Citation and Details
More data for this
Ligand-Target Pair
Serotonin transporter


(Mus musculus)
BDBM50010305
PNG
(CHEMBL3251301)
Show SMILES Cl.NC1CC(C1)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C16H17N.ClH/c17-15-11-16(12-15,13-7-3-1-4-8-13)14-9-5-2-6-10-14;/h1-10,15H,11-12,17H2;1H
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n/an/a 2.80E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of 5-HT transporter in NMRI albino mouse brain assessed as [3H]5-HT accumulation in hypothalamus after 5 mins


J Med Chem 21: 78-82 (1978)

More data for this
Ligand-Target Pair
Serotonin transporter


(Mus musculus)
BDBM50010306
PNG
(CHEMBL3251302)
Show SMILES Cl.CNC1CC(C1)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C17H19N.ClH/c1-18-16-12-17(13-16,14-8-4-2-5-9-14)15-10-6-3-7-11-15;/h2-11,16,18H,12-13H2,1H3;1H
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n/an/a 3.00E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of 5-HT transporter in NMRI albino mouse brain assessed as [3H]5-HT accumulation in hypothalamus after 5 mins


J Med Chem 21: 78-82 (1978)

More data for this
Ligand-Target Pair
Serotonin transporter


(Mus musculus)
BDBM50063512
PNG
(CHEMBL3398502)
Show SMILES COc1ccc(cc1)C(OCCN1CCC[C@@H]1[C@@H](O)C(O)=O)(c1ccc(OC)cc1)c1ccc(OC)cc1
Show InChI InChI=1/C30H35NO7/c1-35-24-12-6-21(7-13-24)30(22-8-14-25(36-2)15-9-22,23-10-16-26(37-3)17-11-23)38-20-19-31-18-4-5-27(31)28(32)29(33)34/h6-17,27-28,32H,4-5,18-20H2,1-3H3,(H,33,34)/t27-,28-/s2
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n/an/a 5.75E+3n/an/an/an/an/an/a



Ludwig-Maximilians-Universit£t M£nchen

Curated by ChEMBL


Assay Description
Inhibition of mouse GAT4 expressed in HEK293 cells by [3H]GABA uptake assay


Citation and Details
More data for this
Ligand-Target Pair
Serotonin transporter


(Mus musculus)
BDBM50063504
PNG
(CHEMBL3398503)
Show SMILES COc1ccc(cc1)C(OCCN1CCC[C@@H]1[C@H](O)C(O)=O)(c1ccc(OC)cc1)c1ccc(OC)cc1
Show InChI InChI=1/C30H35NO7/c1-35-24-12-6-21(7-13-24)30(22-8-14-25(36-2)15-9-22,23-10-16-26(37-3)17-11-23)38-20-19-31-18-4-5-27(31)28(32)29(33)34/h6-17,27-28,32H,4-5,18-20H2,1-3H3,(H,33,34)/t27-,28+/s2
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n/an/a 6.61E+3n/an/an/an/an/an/a



Ludwig-Maximilians-Universit£t M£nchen

Curated by ChEMBL


Assay Description
Inhibition of mouse GAT4 expressed in HEK293 cells by [3H]GABA uptake assay


Citation and Details
More data for this
Ligand-Target Pair
Serotonin transporter


(Mus musculus)
BDBM35229
PNG
(3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N-met...)
Show SMILES CNCCCN1c2ccccc2CCc2ccccc12
Show InChI InChI=1S/C18H22N2/c1-19-13-6-14-20-17-9-4-2-7-15(17)11-12-16-8-3-5-10-18(16)20/h2-5,7-10,19H,6,11-14H2,1H3
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n/an/a 9.30E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of 5-HT transporter in NMRI albino mouse brain assessed as [3H]5-HT accumulation in hypothalamus after 5 mins


J Med Chem 21: 78-82 (1978)

More data for this
Ligand-Target Pair
Serotonin transporter


(Mus musculus)
BDBM50063510
PNG
(CHEMBL3398494)
Show SMILES O[C@H]([C@H]1CCCN1)C(O)=O
Show InChI InChI=1/C6H11NO3/c8-5(6(9)10)4-2-1-3-7-4/h4-5,7-8H,1-3H2,(H,9,10)/t4-,5-/s2
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n/an/a 1.41E+4n/an/an/an/an/an/a



Ludwig-Maximilians-Universit£t M£nchen

Curated by ChEMBL


Assay Description
Inhibition of mouse GAT4 expressed in HEK293 cells by [3H]GABA uptake assay


Citation and Details
More data for this
Ligand-Target Pair
Serotonin transporter


(Mus musculus)
BDBM50063514
PNG
(CHEMBL3398504)
Show SMILES OC(=O)C(F)(F)F.N[C@H]([C@H]1CCCN1CCC=C(c1ccccc1)c1ccccc1)C(O)=O
Show InChI InChI=1/C22H26N2O2/c23-21(22(25)26)20-14-8-16-24(20)15-7-13-19(17-9-3-1-4-10-17)18-11-5-2-6-12-18/h1-6,9-13,20-21H,7-8,14-16,23H2,(H,25,26)/t20-,21-/s2
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n/an/a 1.74E+4n/an/an/an/an/an/a



Ludwig-Maximilians-Universit£t M£nchen

Curated by ChEMBL


Assay Description
Inhibition of mouse GAT4 expressed in HEK293 cells by [3H]GABA uptake assay


Citation and Details
More data for this
Ligand-Target Pair
Serotonin transporter


(Mus musculus)
BDBM50063513
PNG
(CHEMBL3398496)
Show SMILES OC(=O)C(F)(F)F.N[C@H]([C@H]1CCCN1)C(O)=O
Show InChI InChI=1/C6H12N2O2/c7-5(6(9)10)4-2-1-3-8-4/h4-5,8H,1-3,7H2,(H,9,10)/t4-,5-/s2
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n/an/a 2.14E+4n/an/an/an/an/an/a



Ludwig-Maximilians-Universit£t M£nchen

Curated by ChEMBL


Assay Description
Inhibition of mouse GAT4 expressed in HEK293 cells by [3H]GABA uptake assay


Citation and Details
More data for this
Ligand-Target Pair
Serotonin transporter


(Mus musculus)
BDBM50063500
PNG
(CHEMBL3398506)
Show SMILES OC(=O)C(F)(F)F.Cc1ccsc1C(=CCCN1CCC[C@@H]1[C@@H](N)C(O)=O)c1sccc1C
Show InChI InChI=1/C20H26N2O2S2/c1-13-7-11-25-18(13)15(19-14(2)8-12-26-19)5-3-9-22-10-4-6-16(22)17(21)20(23)24/h5,7-8,11-12,16-17H,3-4,6,9-10,21H2,1-2H3,(H,23,24)/t16-,17-/s2
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n/an/a 3.16E+4n/an/an/an/an/an/a



Ludwig-Maximilians-Universit£t M£nchen

Curated by ChEMBL


Assay Description
Inhibition of mouse GAT4 expressed in HEK293 cells by [3H]GABA uptake assay


Citation and Details
More data for this
Ligand-Target Pair
Serotonin transporter


(Mus musculus)
BDBM50005246
PNG
(1-Phenylpropan-2-amin | 1-phenyl-2-aminopropane | ...)
Show SMILES CC(N)Cc1ccccc1
Show InChI InChI=1S/C9H13N/c1-8(10)7-9-5-3-2-4-6-9/h2-6,8H,7,10H2,1H3
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n/an/a 4.50E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of 5-HT transporter in NMRI albino mouse brain assessed as [3H]5-HT accumulation in hypothalamus after 5 mins


J Med Chem 21: 78-82 (1978)

More data for this
Ligand-Target Pair
Serotonin transporter


(Mus musculus)
BDBM50063507
PNG
(CHEMBL3398507)
Show SMILES OC(=O)C(F)(F)F.Cc1ccsc1C(=CCCN1CCC[C@@H]1[C@H](N)C(O)=O)c1sccc1C
Show InChI InChI=1/C20H26N2O2S2/c1-13-7-11-25-18(13)15(19-14(2)8-12-26-19)5-3-9-22-10-4-6-16(22)17(21)20(23)24/h5,7-8,11-12,16-17H,3-4,6,9-10,21H2,1-2H3,(H,23,24)/t16-,17+/s2
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n/an/a 1.00E+5n/an/an/an/an/an/a



Ludwig-Maximilians-Universit£t M£nchen

Curated by ChEMBL


Assay Description
Inhibition of mouse GAT4 expressed in HEK293 cells by [3H]GABA uptake assay


Citation and Details
More data for this
Ligand-Target Pair
Serotonin transporter


(Mus musculus)
BDBM50063509
PNG
((S)-Homoproline | CHEMBL1164855)
Show SMILES OC(=O)C[C@@H]1CCCN1
Show InChI InChI=1/C6H11NO2/c8-6(9)4-5-2-1-3-7-5/h5,7H,1-4H2,(H,8,9)/t5-/s2
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n/an/a 1.74E+5n/an/an/an/an/an/a



Ludwig-Maximilians-Universit£t M£nchen

Curated by ChEMBL


Assay Description
Inhibition of mouse GAT4 expressed in HEK293 cells by [3H]GABA uptake assay


Citation and Details
More data for this
Ligand-Target Pair
Serotonin transporter


(Mus musculus)
BDBM50063501
PNG
(CHEMBL3398490)
Show SMILES CC([C@H]1CCCN1)C(O)=O
Show InChI InChI=1/C7H13NO2/c1-5(7(9)10)6-3-2-4-8-6/h5-6,8H,2-4H2,1H3,(H,9,10)/t5?,6-/s2
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n/an/a 3.39E+5n/an/an/an/an/an/a



Ludwig-Maximilians-Universit£t M£nchen

Curated by ChEMBL


Assay Description
Inhibition of mouse GAT4 expressed in HEK293 cells by [3H]GABA uptake assay


Citation and Details
More data for this
Ligand-Target Pair
Serotonin transporter


(Mus musculus)
BDBM50063505
PNG
(CHEMBL3398497)
Show SMILES OC(=O)C(F)(F)F.N[C@@H]([C@H]1CCCN1)C(O)=O
Show InChI InChI=1/C6H12N2O2/c7-5(6(9)10)4-2-1-3-8-4/h4-5,8H,1-3,7H2,(H,9,10)/t4-,5+/s2
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n/an/a 3.72E+5n/an/an/an/an/an/a



Ludwig-Maximilians-Universit£t M£nchen

Curated by ChEMBL


Assay Description
Inhibition of mouse GAT4 expressed in HEK293 cells by [3H]GABA uptake assay


Citation and Details
More data for this
Ligand-Target Pair
Serotonin transporter


(Mus musculus)
BDBM50063499
PNG
((R)-Homoproline | CHEMBL1163348)
Show SMILES OC(=O)C[C@H]1CCCN1
Show InChI InChI=1/C6H11NO2/c8-6(9)4-5-2-1-3-7-5/h5,7H,1-4H2,(H,8,9)/t5-/s2
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n/an/a 1.12E+6n/an/an/an/an/an/a



Ludwig-Maximilians-Universit£t M£nchen

Curated by ChEMBL


Assay Description
Inhibition of mouse GAT4 expressed in HEK293 cells by [3H]GABA uptake assay


Citation and Details
More data for this
Ligand-Target Pair