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Compile Data Set for Download or QSAR

Found 64 hits Enz. Inhib. hit(s) with Target = 'Sialidase 4' AND taxid = 9606   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sialidase 4


(Homo sapiens)
BDBM50331678
PNG
((2R,3R,4S)-3-acetamido-2-((1R,2R)-1,2-dihydroxy-3-...)
Show SMILES CC(=O)N[C@@H]1[C@@H](O)C=C(O[C@H]1[C@H](O)[C@H](O)Cn1cc(CO)nn1)C(O)=O
Show InChI InChI=1S/C14H20N4O8/c1-6(20)15-11-8(21)2-10(14(24)25)26-13(11)12(23)9(22)4-18-3-7(5-19)16-17-18/h2-3,8-9,11-13,19,21-23H,4-5H2,1H3,(H,15,20)(H,24,25)/t8-,9+,11+,12+,13+/m0/s1
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30n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human NEU4 using 4-MU-NANA as substrate measured every 30 seconds for 60 mins by fluorescence plate reader analysis


Citation and Details
More data for this
Ligand-Target Pair
Sialidase 4


(Homo sapiens)
BDBM50331679
PNG
((2R,3R,4S)-3-acetamido-2-((1R,2R)-1,2-dihydroxy-3-...)
Show SMILES CC(=O)N[C@@H]1[C@@H](O)C=C(O[C@H]1[C@H](O)[C@H](O)Cn1cc(CCO)nn1)C(O)=O
Show InChI InChI=1S/C15H22N4O8/c1-7(21)16-12-9(22)4-11(15(25)26)27-14(12)13(24)10(23)6-19-5-8(2-3-20)17-18-19/h4-5,9-10,12-14,20,22-24H,2-3,6H2,1H3,(H,16,21)(H,25,26)/t9-,10+,12+,13+,14+/m0/s1
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60n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human NEU4 using 4-MU-NANA as substrate measured every 30 seconds for 60 mins by fluorescence plate reader analysis


Citation and Details
More data for this
Ligand-Target Pair
Sialidase 4


(Homo sapiens)
BDBM4706
PNG
((2R,3R,4S)-3-acetamido-4-hydroxy-2-[(1R,2R)-1,2,3-...)
Show SMILES CC(=O)N[C@@H]1[C@@H](O)C=C(O[C@H]1[C@H](O)[C@H](O)CO)C(O)=O
Show InChI InChI=1S/C11H17NO8/c1-4(14)12-8-5(15)2-7(11(18)19)20-10(8)9(17)6(16)3-13/h2,5-6,8-10,13,15-17H,3H2,1H3,(H,12,14)(H,18,19)/t5-,6+,8+,9+,10+/m0/s1
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1.00E+3n/an/an/an/an/an/an/an/a



University of Alberta

Curated by ChEMBL


Assay Description
Inhibition of human neuraminidase 4 using 4MU-NANA as substrate measured for every 30 seconds for 60 mins by fluorescence assay


J Med Chem 56: 2948-58 (2013)

More data for this
Ligand-Target Pair
Sialidase 4


(Homo sapiens)
BDBM50331678
PNG
((2R,3R,4S)-3-acetamido-2-((1R,2R)-1,2-dihydroxy-3-...)
Show SMILES CC(=O)N[C@@H]1[C@@H](O)C=C(O[C@H]1[C@H](O)[C@H](O)Cn1cc(CO)nn1)C(O)=O
Show InChI InChI=1S/C14H20N4O8/c1-6(20)15-11-8(21)2-10(14(24)25)26-13(11)12(23)9(22)4-18-3-7(5-19)16-17-18/h2-3,8-9,11-13,19,21-23H,4-5H2,1H3,(H,15,20)(H,24,25)/t8-,9+,11+,12+,13+/m0/s1
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n/an/a 160n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human NEU4 using 4-MU-NANA as substrate preincubated for 15 mins before substrate addition measured after 30 mins by fluorescence plate...


Citation and Details
More data for this
Ligand-Target Pair
Sialidase 4


(Homo sapiens)
BDBM50331678
PNG
((2R,3R,4S)-3-acetamido-2-((1R,2R)-1,2-dihydroxy-3-...)
Show SMILES CC(=O)N[C@@H]1[C@@H](O)C=C(O[C@H]1[C@H](O)[C@H](O)Cn1cc(CO)nn1)C(O)=O
Show InChI InChI=1S/C14H20N4O8/c1-6(20)15-11-8(21)2-10(14(24)25)26-13(11)12(23)9(22)4-18-3-7(5-19)16-17-18/h2-3,8-9,11-13,19,21-23H,4-5H2,1H3,(H,15,20)(H,24,25)/t8-,9+,11+,12+,13+/m0/s1
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n/an/a 740n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human NEU4 using GM3 as substrate preincubated for 30 mins before substrate addition measured after 1 hr by fluorescence plate reader a...


Citation and Details
More data for this
Ligand-Target Pair
Sialidase 4


(Homo sapiens)
BDBM50331679
PNG
((2R,3R,4S)-3-acetamido-2-((1R,2R)-1,2-dihydroxy-3-...)
Show SMILES CC(=O)N[C@@H]1[C@@H](O)C=C(O[C@H]1[C@H](O)[C@H](O)Cn1cc(CCO)nn1)C(O)=O
Show InChI InChI=1S/C15H22N4O8/c1-7(21)16-12-9(22)4-11(15(25)26)27-14(12)13(24)10(23)6-19-5-8(2-3-20)17-18-19/h4-5,9-10,12-14,20,22-24H,2-3,6H2,1H3,(H,16,21)(H,25,26)/t9-,10+,12+,13+,14+/m0/s1
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n/an/a 810n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human NEU4 using 4-MU-NANA as substrate preincubated for 15 mins before substrate addition measured after 30 mins by fluorescence plate...


Citation and Details
More data for this
Ligand-Target Pair
Sialidase 4


(Homo sapiens)
BDBM50331677
PNG
((2R,3R,4S)-3-acetamido-2-((1R,2R)-1,2-dihydroxy-3-...)
Show SMILES CC(=O)N[C@@H]1[C@@H](O)C=C(O[C@H]1[C@H](O)[C@H](O)Cn1cc(COc2ccccc2)nn1)C(O)=O
Show InChI InChI=1S/C20H24N4O8/c1-11(25)21-17-14(26)7-16(20(29)30)32-19(17)18(28)15(27)9-24-8-12(22-23-24)10-31-13-5-3-2-4-6-13/h2-8,14-15,17-19,26-28H,9-10H2,1H3,(H,21,25)(H,29,30)/t14-,15+,17+,18+,19+/m0/s1
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n/an/a 1.70E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human NEU4 using 4-MU-NANA as substrate preincubated for 15 mins before substrate addition measured after 30 mins by fluorescence plate...


Citation and Details
More data for this
Ligand-Target Pair
Sialidase 4


(Homo sapiens)
BDBM50331680
PNG
((2R,3R,4S)-3-acetamido-2-((1R,2R)-1,2-dihydroxy-3-...)
Show SMILES CC(=O)N[C@@H]1[C@@H](O)C=C(O[C@H]1[C@H](O)[C@H](O)Cn1cc(CCCO)nn1)C(O)=O
Show InChI InChI=1S/C16H24N4O8/c1-8(22)17-13-10(23)5-12(16(26)27)28-15(13)14(25)11(24)7-20-6-9(18-19-20)3-2-4-21/h5-6,10-11,13-15,21,23-25H,2-4,7H2,1H3,(H,17,22)(H,26,27)/t10-,11+,13+,14+,15+/m0/s1
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n/an/a 2.10E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human NEU4 using 4-MU-NANA as substrate preincubated for 15 mins before substrate addition measured after 30 mins by fluorescence plate...


Citation and Details
More data for this
Ligand-Target Pair
Sialidase 4


(Homo sapiens)
BDBM50331673
PNG
((2R,3R,4S)-3-acetamido-2-((1R,2R)-1,2-dihydroxy-3-...)
Show SMILES CC(=O)N[C@@H]1[C@@H](O)C=C(O[C@H]1[C@H](O)[C@H](O)Cn1cc(nn1)-c1ccccc1)C(O)=O
Show InChI InChI=1S/C19H22N4O7/c1-10(24)20-16-13(25)7-15(19(28)29)30-18(16)17(27)14(26)9-23-8-12(21-22-23)11-5-3-2-4-6-11/h2-8,13-14,16-18,25-27H,9H2,1H3,(H,20,24)(H,28,29)/t13-,14+,16+,17+,18+/m0/s1
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n/an/a 2.30E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human NEU4 using 4-MU-NANA as substrate preincubated for 15 mins before substrate addition measured after 30 mins by fluorescence plate...


Citation and Details
More data for this
Ligand-Target Pair
Sialidase 4


(Homo sapiens)
BDBM50331675
PNG
((2R,3R,4S)-3-acetamido-2-((1R,2R)-3-(4-ethoxy-1H-1...)
Show SMILES CCOc1cn(C[C@@H](O)[C@@H](O)[C@@H]2OC(=C[C@H](O)[C@H]2NC(C)=O)C(O)=O)nn1
Show InChI InChI=1S/C15H22N4O8/c1-3-26-11-6-19(18-17-11)5-9(22)13(23)14-12(16-7(2)20)8(21)4-10(27-14)15(24)25/h4,6,8-9,12-14,21-23H,3,5H2,1-2H3,(H,16,20)(H,24,25)/t8-,9+,12+,13+,14+/m0/s1
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n/an/a 3.60E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human NEU4 using 4-MU-NANA as substrate preincubated for 15 mins before substrate addition measured after 30 mins by fluorescence plate...


Citation and Details
More data for this
Ligand-Target Pair
Sialidase 4


(Homo sapiens)
BDBM50331681
PNG
((2R,3R,4S)-3-acetamido-2-((1R,2R)-1,2-dihydroxy-3-...)
Show SMILES CC(=O)N[C@@H]1[C@@H](O)C=C(O[C@H]1[C@H](O)[C@H](O)Cn1cc(nn1)C(C)(C)O)C(O)=O
Show InChI InChI=1S/C16H24N4O8/c1-7(21)17-12-8(22)4-10(15(25)26)28-14(12)13(24)9(23)5-20-6-11(18-19-20)16(2,3)27/h4,6,8-9,12-14,22-24,27H,5H2,1-3H3,(H,17,21)(H,25,26)/t8-,9+,12+,13+,14+/m0/s1
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n/an/a 4.00E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human NEU4 using 4-MU-NANA as substrate preincubated for 15 mins before substrate addition measured after 30 mins by fluorescence plate...


Citation and Details
More data for this
Ligand-Target Pair
Sialidase 4


(Homo sapiens)
BDBM50331682
PNG
((2R,3R,4S)-3-(2-azidoacetamido)-4-hydroxy-2-((1R,2...)
Show SMILES OC[C@@H](O)[C@@H](O)[C@@H]1OC(=C[C@H](O)[C@H]1NC(=O)CN=[N+]=[N-])C(O)=O
Show InChI InChI=1S/C11H16N4O8/c12-15-13-2-7(19)14-8-4(17)1-6(11(21)22)23-10(8)9(20)5(18)3-16/h1,4-5,8-10,16-18,20H,2-3H2,(H,14,19)(H,21,22)/t4-,5+,8+,9+,10+/m0/s1
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n/an/a 4.50E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human NEU4 using 4-MU-NANA as substrate preincubated for 15 mins before substrate addition measured after 30 mins by fluorescence plate...


Citation and Details
More data for this
Ligand-Target Pair
Sialidase 4


(Homo sapiens)
BDBM4706
PNG
((2R,3R,4S)-3-acetamido-4-hydroxy-2-[(1R,2R)-1,2,3-...)
Show SMILES CC(=O)N[C@@H]1[C@@H](O)C=C(O[C@H]1[C@H](O)[C@H](O)CO)C(O)=O
Show InChI InChI=1S/C11H17NO8/c1-4(14)12-8-5(15)2-7(11(18)19)20-10(8)9(17)6(16)3-13/h2,5-6,8-10,13,15-17H,3H2,1H3,(H,12,14)(H,18,19)/t5-,6+,8+,9+,10+/m0/s1
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n/an/a 1.30E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human NEU4 using 4-MU-NANA as substrate preincubated for 15 mins before substrate addition measured after 30 mins by fluorescence plate...


Citation and Details
More data for this
Ligand-Target Pair
Sialidase 4


(Homo sapiens)
BDBM4706
PNG
((2R,3R,4S)-3-acetamido-4-hydroxy-2-[(1R,2R)-1,2,3-...)
Show SMILES CC(=O)N[C@@H]1[C@@H](O)C=C(O[C@H]1[C@H](O)[C@H](O)CO)C(O)=O
Show InChI InChI=1S/C11H17NO8/c1-4(14)12-8-5(15)2-7(11(18)19)20-10(8)9(17)6(16)3-13/h2,5-6,8-10,13,15-17H,3H2,1H3,(H,12,14)(H,18,19)/t5-,6+,8+,9+,10+/m0/s1
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n/an/a 1.30E+4n/an/an/an/an/an/a



University of Alberta

Curated by ChEMBL


Assay Description
Inhibition of human neuraminidase 4 using 4MU-NANA as substrate after 30 mins by fluorescence assay


J Med Chem 56: 2948-58 (2013)

More data for this
Ligand-Target Pair
Sialidase 4


(Homo sapiens)
BDBM4706
PNG
((2R,3R,4S)-3-acetamido-4-hydroxy-2-[(1R,2R)-1,2,3-...)
Show SMILES CC(=O)N[C@@H]1[C@@H](O)C=C(O[C@H]1[C@H](O)[C@H](O)CO)C(O)=O
Show InChI InChI=1S/C11H17NO8/c1-4(14)12-8-5(15)2-7(11(18)19)20-10(8)9(17)6(16)3-13/h2,5-6,8-10,13,15-17H,3H2,1H3,(H,12,14)(H,18,19)/t5-,6+,8+,9+,10+/m0/s1
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n/an/a 2.20E+4n/an/an/an/an/an/a



University of Alberta

Curated by ChEMBL


Assay Description
Inhibition of human NEU4 using 4MU-NA as substrate after 1 hr by fluorescence assay


Bioorg Med Chem 19: 2817-22 (2011)

More data for this
Ligand-Target Pair
Sialidase 4


(Homo sapiens)
BDBM4706
PNG
((2R,3R,4S)-3-acetamido-4-hydroxy-2-[(1R,2R)-1,2,3-...)
Show SMILES CC(=O)N[C@@H]1[C@@H](O)C=C(O[C@H]1[C@H](O)[C@H](O)CO)C(O)=O
Show InChI InChI=1S/C11H17NO8/c1-4(14)12-8-5(15)2-7(11(18)19)20-10(8)9(17)6(16)3-13/h2,5-6,8-10,13,15-17H,3H2,1H3,(H,12,14)(H,18,19)/t5-,6+,8+,9+,10+/m0/s1
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n/an/a 5.00E+4n/an/an/an/an/an/a



Thammasat University

Curated by ChEMBL


Assay Description
Inhibition of human Neu4 expressed in HEK293T cells using 4MU-Neu5Ac as substrate incubated for 30 mins by HPLC analysis


J Med Chem 59: 4563-77 (2016)

More data for this
Ligand-Target Pair
Sialidase 4


(Homo sapiens)
BDBM4706
PNG
((2R,3R,4S)-3-acetamido-4-hydroxy-2-[(1R,2R)-1,2,3-...)
Show SMILES CC(=O)N[C@@H]1[C@@H](O)C=C(O[C@H]1[C@H](O)[C@H](O)CO)C(O)=O
Show InChI InChI=1S/C11H17NO8/c1-4(14)12-8-5(15)2-7(11(18)19)20-10(8)9(17)6(16)3-13/h2,5-6,8-10,13,15-17H,3H2,1H3,(H,12,14)(H,18,19)/t5-,6+,8+,9+,10+/m0/s1
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n/an/a 5.00E+4n/an/an/an/an/an/a



Thammasat University

Curated by ChEMBL


Assay Description
Inhibition of human Neu4 expressed in HEK293T cells using GM3 as substrate incubated for 30 mins by HPLC analysis


J Med Chem 59: 4563-77 (2016)

More data for this
Ligand-Target Pair
Sialidase 4


(Homo sapiens)
BDBM50331692
PNG
((2R,3R,4S)-3-acetamido-2-((1R,2R)-3-azido-1,2-dihy...)
Show SMILES CC(=O)N[C@@H]1[C@@H](O)C=C(O[C@H]1[C@H](O)[C@H](O)CN=[N+]=[N-])C(O)=O
Show InChI InChI=1S/C11H16N4O7/c1-4(16)14-8-5(17)2-7(11(20)21)22-10(8)9(19)6(18)3-13-15-12/h2,5-6,8-10,17-19H,3H2,1H3,(H,14,16)(H,20,21)/t5-,6+,8+,9+,10+/m0/s1
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n/an/a 6.00E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human NEU4 using 4-MU-NANA as substrate preincubated for 15 mins before substrate addition measured after 30 mins by fluorescence plate...


Citation and Details
More data for this
Ligand-Target Pair
Sialidase 4


(Homo sapiens)
BDBM4706
PNG
((2R,3R,4S)-3-acetamido-4-hydroxy-2-[(1R,2R)-1,2,3-...)
Show SMILES CC(=O)N[C@@H]1[C@@H](O)C=C(O[C@H]1[C@H](O)[C@H](O)CO)C(O)=O
Show InChI InChI=1S/C11H17NO8/c1-4(14)12-8-5(15)2-7(11(18)19)20-10(8)9(17)6(16)3-13/h2,5-6,8-10,13,15-17H,3H2,1H3,(H,12,14)(H,18,19)/t5-,6+,8+,9+,10+/m0/s1
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n/an/a 7.00E+4n/an/an/an/an/an/a



Gifu University

Curated by ChEMBL


Assay Description
Inhibition of human NEU4 transiently transfected in HEK293T cells by fluorimetric analysis


Bioorg Med Chem 17: 4595-603 (2009)

More data for this
Ligand-Target Pair
Sialidase 4


(Homo sapiens)
BDBM4706
PNG
((2R,3R,4S)-3-acetamido-4-hydroxy-2-[(1R,2R)-1,2,3-...)
Show SMILES CC(=O)N[C@@H]1[C@@H](O)C=C(O[C@H]1[C@H](O)[C@H](O)CO)C(O)=O
Show InChI InChI=1S/C11H17NO8/c1-4(14)12-8-5(15)2-7(11(18)19)20-10(8)9(17)6(16)3-13/h2,5-6,8-10,13,15-17H,3H2,1H3,(H,12,14)(H,18,19)/t5-,6+,8+,9+,10+/m0/s1
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n/an/a 7.31E+4n/an/an/an/an/an/a



Miyagi Cancer Center Research Institute

Curated by ChEMBL


Assay Description
Inhibition of human NEU4 expressed in HEK293 cells by fluorometric high-performance liquid chromatography using 4MU-NeuAc substrate


Antimicrob Agents Chemother 52: 3484-91 (2008)

More data for this
Ligand-Target Pair
Sialidase 4


(Homo sapiens)
BDBM4706
PNG
((2R,3R,4S)-3-acetamido-4-hydroxy-2-[(1R,2R)-1,2,3-...)
Show SMILES CC(=O)N[C@@H]1[C@@H](O)C=C(O[C@H]1[C@H](O)[C@H](O)CO)C(O)=O
Show InChI InChI=1S/C11H17NO8/c1-4(14)12-8-5(15)2-7(11(18)19)20-10(8)9(17)6(16)3-13/h2,5-6,8-10,13,15-17H,3H2,1H3,(H,12,14)(H,18,19)/t5-,6+,8+,9+,10+/m0/s1
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n/an/a 7.40E+4n/an/an/an/an/an/a



Gifu University

Curated by ChEMBL


Assay Description
Inhibition of human NEU4 expressed in HEK293 cells


Bioorg Med Chem Lett 18: 532-7 (2008)

More data for this
Ligand-Target Pair
Sialidase 4


(Homo sapiens)
BDBM50428075
PNG
(CHEMBL2323564)
Show SMILES CC(=O)N[C@@H]1[C@@H](O)C=C(O[C@H]1CNNCc1ccc(cc1)-c1ccccc1)C(O)=O
Show InChI InChI=1S/C22H25N3O5/c1-14(26)25-21-18(27)11-19(22(28)29)30-20(21)13-24-23-12-15-7-9-17(10-8-15)16-5-3-2-4-6-16/h2-11,18,20-21,23-24,27H,12-13H2,1H3,(H,25,26)(H,28,29)/t18-,20-,21+/m0/s1
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n/an/a 2.00E+5n/an/an/an/an/an/a



University of Alberta

Curated by ChEMBL


Assay Description
Inhibition of human neuraminidase 4 using 4MU-NANA as substrate measured for every 30 seconds for 60 mins by fluorescence assay


J Med Chem 56: 2948-58 (2013)

More data for this
Ligand-Target Pair
Sialidase 4


(Homo sapiens)
BDBM50428072
PNG
(CHEMBL2325810)
Show SMILES CC(=O)N[C@H]1[C@H](CNc2ccc(cc2)-c2ccccc2)OC(=C[C@@H]1N=[N+]=[N-])C(O)=O
Show InChI InChI=1S/C21H21N5O4/c1-13(27)24-20-17(25-26-22)11-18(21(28)29)30-19(20)12-23-16-9-7-15(8-10-16)14-5-3-2-4-6-14/h2-11,17,19-20,23H,12H2,1H3,(H,24,27)(H,28,29)/t17-,19-,20+/m0/s1
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n/an/a 2.10E+5n/an/an/an/an/an/a



University of Alberta

Curated by ChEMBL


Assay Description
Inhibition of human neuraminidase 4 using 4MU-NANA as substrate measured for every 30 seconds for 60 mins by fluorescence assay


J Med Chem 56: 2948-58 (2013)

More data for this
Ligand-Target Pair
Sialidase 4


(Homo sapiens)
BDBM50331683
PNG
((2R,3R,4S)-4-hydroxy-3-(2-(4-phenyl-1H-1,2,3-triaz...)
Show SMILES OC[C@@H](O)[C@@H](O)[C@@H]1OC(=C[C@H](O)[C@H]1NC(=O)Cn1cc(nn1)-c1ccccc1)C(O)=O
Show InChI InChI=1S/C19H22N4O8/c24-9-13(26)17(28)18-16(12(25)6-14(31-18)19(29)30)20-15(27)8-23-7-11(21-22-23)10-4-2-1-3-5-10/h1-7,12-13,16-18,24-26,28H,8-9H2,(H,20,27)(H,29,30)/t12-,13+,16+,17+,18+/m0/s1
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n/an/a 2.50E+5n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human NEU4 using 4-MU-NANA as substrate preincubated for 15 mins before substrate addition measured after 30 mins by fluorescence plate...


Citation and Details
More data for this
Ligand-Target Pair
Sialidase 4


(Homo sapiens)
BDBM4706
PNG
((2R,3R,4S)-3-acetamido-4-hydroxy-2-[(1R,2R)-1,2,3-...)
Show SMILES CC(=O)N[C@@H]1[C@@H](O)C=C(O[C@H]1[C@H](O)[C@H](O)CO)C(O)=O
Show InChI InChI=1S/C11H17NO8/c1-4(14)12-8-5(15)2-7(11(18)19)20-10(8)9(17)6(16)3-13/h2,5-6,8-10,13,15-17H,3H2,1H3,(H,12,14)(H,18,19)/t5-,6+,8+,9+,10+/m0/s1
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n/an/a 2.60E+5n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human NEU4 using GM3 as substrate preincubated for 30 mins before substrate addition measured after 1 hr by fluorescence plate reader a...


Citation and Details
More data for this
Ligand-Target Pair
Sialidase 4


(Homo sapiens)
BDBM50428073
PNG
(CHEMBL2325809)
Show SMILES CC(=O)N[C@H]1[C@H](CNc2ccccc2)OC(=C[C@@H]1N=[N+]=[N-])C(O)=O
Show InChI InChI=1S/C15H17N5O4/c1-9(21)18-14-11(19-20-16)7-12(15(22)23)24-13(14)8-17-10-5-3-2-4-6-10/h2-7,11,13-14,17H,8H2,1H3,(H,18,21)(H,22,23)/t11-,13-,14+/m0/s1
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n/an/a 3.00E+5n/an/an/an/an/an/a



University of Alberta

Curated by ChEMBL


Assay Description
Inhibition of human neuraminidase 4 using 4MU-NANA as substrate measured for every 30 seconds for 60 mins by fluorescence assay


J Med Chem 56: 2948-58 (2013)

More data for this
Ligand-Target Pair
Sialidase 4


(Homo sapiens)
BDBM50428070
PNG
(CHEMBL2325812)
Show SMILES CC(=O)N[C@H]1[C@H](CN(Cc2ccccc2)OCc2ccccc2)OC(=C[C@@H]1N=[N+]=[N-])C(O)=O
Show InChI InChI=1S/C23H25N5O5/c1-16(29)25-22-19(26-27-24)12-20(23(30)31)33-21(22)14-28(13-17-8-4-2-5-9-17)32-15-18-10-6-3-7-11-18/h2-12,19,21-22H,13-15H2,1H3,(H,25,29)(H,30,31)/t19-,21-,22+/m0/s1
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n/an/a 3.50E+5n/an/an/an/an/an/a



University of Alberta

Curated by ChEMBL


Assay Description
Inhibition of human neuraminidase 4 using 4MU-NANA as substrate measured for every 30 seconds for 60 mins by fluorescence assay


J Med Chem 56: 2948-58 (2013)

More data for this
Ligand-Target Pair
Sialidase 4


(Homo sapiens)
BDBM50330326
PNG
((4S,5R,6R)-5-Acetylamino-4-guanidino-6-((1R,3R)-1,...)
Show SMILES CC(=O)N[C@@H]1[C@H](C=C(O[C@H]1[C@H](O)[C@H](O)CO)C(O)=O)N=C(N)N
Show InChI InChI=1S/C12H20N4O7/c1-4(18)15-8-5(16-12(13)14)2-7(11(21)22)23-10(8)9(20)6(19)3-17/h2,5-6,8-10,17,19-20H,3H2,1H3,(H,15,18)(H,21,22)(H4,13,14,16)/t5-,6+,8+,9+,10+/m0/s1
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n/an/a 3.92E+5n/an/an/an/an/an/a



Thammasat University

Curated by ChEMBL


Assay Description
Inhibition of human Neu4 expressed in HEK293T cells using 4MU-Neu5Ac as substrate incubated for 30 mins by HPLC analysis


J Med Chem 59: 4563-77 (2016)

More data for this
Ligand-Target Pair
Sialidase 4


(Homo sapiens)
BDBM50330326
PNG
((4S,5R,6R)-5-Acetylamino-4-guanidino-6-((1R,3R)-1,...)
Show SMILES CC(=O)N[C@@H]1[C@H](C=C(O[C@H]1[C@H](O)[C@H](O)CO)C(O)=O)N=C(N)N
Show InChI InChI=1S/C12H20N4O7/c1-4(18)15-8-5(16-12(13)14)2-7(11(21)22)23-10(8)9(20)6(19)3-17/h2,5-6,8-10,17,19-20H,3H2,1H3,(H,15,18)(H,21,22)(H4,13,14,16)/t5-,6+,8+,9+,10+/m0/s1
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n/an/a 4.87E+5n/an/an/an/an/an/a



Miyagi Cancer Center Research Institute

Curated by ChEMBL


Assay Description
Inhibition of human NEU4 expressed in HEK293 cells by fluorometric high-performance liquid chromatography using 4MU-NeuAc substrate


Antimicrob Agents Chemother 52: 3484-91 (2008)

More data for this
Ligand-Target Pair
Sialidase 4


(Homo sapiens)
BDBM50229632
PNG
((4S,5R,6R)-5-acetamido-6-((1S,2S)-3-acetamido-1,2-...)
Show SMILES CC(=O)NC[C@H](O)[C@H](O)[C@@H]1OC(=C[C@H](O)[C@H]1NC(C)=O)C(O)=O
Show InChI InChI=1S/C13H20N2O8/c1-5(16)14-4-8(19)11(20)12-10(15-6(2)17)7(18)3-9(23-12)13(21)22/h3,7-8,10-12,18-20H,4H2,1-2H3,(H,14,16)(H,15,17)(H,21,22)/t7-,8-,10+,11-,12+/m0/s1
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n/an/a 5.80E+5n/an/an/an/an/an/a



Gifu University

Curated by ChEMBL


Assay Description
Inhibition of human NEU4 expressed in HEK293 cells


Bioorg Med Chem Lett 18: 532-7 (2008)

More data for this
Ligand-Target Pair
Sialidase 4


(Homo sapiens)
BDBM50330326
PNG
((4S,5R,6R)-5-Acetylamino-4-guanidino-6-((1R,3R)-1,...)
Show SMILES CC(=O)N[C@@H]1[C@H](C=C(O[C@H]1[C@H](O)[C@H](O)CO)C(O)=O)N=C(N)N
Show InChI InChI=1S/C12H20N4O7/c1-4(18)15-8-5(16-12(13)14)2-7(11(21)22)23-10(8)9(20)6(19)3-17/h2,5-6,8-10,17,19-20H,3H2,1H3,(H,15,18)(H,21,22)(H4,13,14,16)/t5-,6+,8+,9+,10+/m0/s1
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n/an/a 6.90E+5n/an/an/an/an/an/a



Miyagi Cancer Center Research Institute

Curated by ChEMBL


Assay Description
Inhibition of human NEU4 expressed in HEK293 cells by fluorometric high-performance liquid chromatography using ganglioside GM3 substrate


Antimicrob Agents Chemother 52: 3484-91 (2008)

More data for this
Ligand-Target Pair
Sialidase 4


(Homo sapiens)
BDBM50182216
PNG
(CHEMBL3819510)
Show SMILES OC(=O)C(F)(F)F.CCCCC(=O)NC[C@@H](O)[C@@H](O)[C@@H]1OC(=C[C@H](NC(N)=N)[C@H]1NC(C)=O)C(O)=O
Show InChI InChI=1/C17H29N5O7.C2HF3O2/c1-3-4-5-12(25)20-7-10(24)14(26)15-13(21-8(2)23)9(22-17(18)19)6-11(29-15)16(27)28;3-2(4,5)1(6)7/h6,9-10,13-15,24,26H,3-5,7H2,1-2H3,(H,20,25)(H,21,23)(H,27,28)(H4,18,19,22);(H,6,7)/t9-,10+,13+,14+,15+;/s2
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n/an/a>7.00E+5n/an/an/an/an/an/a



Thammasat University

Curated by ChEMBL


Assay Description
Inhibition of human Neu4 expressed in HEK293T cells using 4MU-Neu5Ac as substrate incubated for 30 mins by HPLC analysis


J Med Chem 59: 4563-77 (2016)

More data for this
Ligand-Target Pair
Sialidase 4


(Homo sapiens)
BDBM50182216
PNG
(CHEMBL3819510)
Show SMILES OC(=O)C(F)(F)F.CCCCC(=O)NC[C@@H](O)[C@@H](O)[C@@H]1OC(=C[C@H](NC(N)=N)[C@H]1NC(C)=O)C(O)=O
Show InChI InChI=1/C17H29N5O7.C2HF3O2/c1-3-4-5-12(25)20-7-10(24)14(26)15-13(21-8(2)23)9(22-17(18)19)6-11(29-15)16(27)28;3-2(4,5)1(6)7/h6,9-10,13-15,24,26H,3-5,7H2,1-2H3,(H,20,25)(H,21,23)(H,27,28)(H4,18,19,22);(H,6,7)/t9-,10+,13+,14+,15+;/s2
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n/an/a>7.00E+5n/an/an/an/an/an/a



Thammasat University

Curated by ChEMBL


Assay Description
Inhibition of human Neu4 expressed in HEK293T cells using GM3 as substrate incubated for 30 mins by HPLC analysis


J Med Chem 59: 4563-77 (2016)

More data for this
Ligand-Target Pair
Sialidase 4


(Homo sapiens)
BDBM50063303
PNG
((2R,3R,4S)-3-acetamido-4-amino-2-((1R,2R)-1,2,3-tr...)
Show SMILES CC(=O)N[C@@H]1[C@@H](N)C=C(O[C@H]1[C@H](O)[C@H](O)CO)C(O)=O
Show InChI InChI=1S/C11H18N2O7/c1-4(15)13-8-5(12)2-7(11(18)19)20-10(8)9(17)6(16)3-14/h2,5-6,8-10,14,16-17H,3,12H2,1H3,(H,13,15)(H,18,19)/t5-,6+,8+,9+,10+/m0/s1
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n/an/a 7.20E+5n/an/an/an/an/an/a



University of Alberta

Curated by ChEMBL


Assay Description
Inhibition of human neuraminidase 4 using 4MU-NANA as substrate measured for every 30 seconds for 60 mins by fluorescence assay


J Med Chem 56: 2948-58 (2013)

More data for this
Ligand-Target Pair
Sialidase 4


(Homo sapiens)
BDBM50343689
PNG
((3S,4R,5R)-4-acetamido-3-(4-((8R,9S,13S,14S,17S)-3...)
Show SMILES CCC(CC)O[C@@H]1CC(=C[C@@H]([C@H]1NC(C)=O)n1cc(nn1)[C@]1(O)CC[C@H]2[C@@H]3CCc4cc(O)ccc4[C@H]3CC[C@]12C)C(O)=O
Show InChI InChI=1S/C34H46N4O6/c1-5-23(6-2)44-29-17-21(32(41)42)16-28(31(29)35-19(3)39)38-18-30(36-37-38)34(43)14-12-27-26-9-7-20-15-22(40)8-10-24(20)25(26)11-13-33(27,34)4/h8,10,15-16,18,23,25-29,31,40,43H,5-7,9,11-14,17H2,1-4H3,(H,35,39)(H,41,42)/t25-,26-,27+,28+,29-,31-,33+,34-/m1/s1
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n/an/a 8.00E+5n/an/an/an/an/an/a



University of Alberta

Curated by ChEMBL


Assay Description
Inhibition of human NEU4 using 4MU-NA as substrate after 1 hr by fluorescence assay


Bioorg Med Chem 19: 2817-22 (2011)

More data for this
Ligand-Target Pair
Sialidase 4


(Homo sapiens)
BDBM50229625
PNG
((4S,5R,6R)-5-acetamido-6-((1S,2S)-3-benzamido-1,2-...)
Show SMILES CC(=O)N[C@@H]1[C@@H](O)C=C(O[C@H]1[C@@H](O)[C@@H](O)CNC(=O)c1ccccc1)C(O)=O
Show InChI InChI=1S/C18H22N2O8/c1-9(21)20-14-11(22)7-13(18(26)27)28-16(14)15(24)12(23)8-19-17(25)10-5-3-2-4-6-10/h2-7,11-12,14-16,22-24H,8H2,1H3,(H,19,25)(H,20,21)(H,26,27)/t11-,12-,14+,15-,16+/m0/s1
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n/an/a 8.10E+5n/an/an/an/an/an/a



Gifu University

Curated by ChEMBL


Assay Description
Inhibition of human NEU4 expressed in HEK293 cells


Bioorg Med Chem Lett 18: 532-7 (2008)

More data for this
Ligand-Target Pair
Sialidase 4


(Homo sapiens)
BDBM50229624
PNG
((4S,5R,6R)-5-acetamido-6-((1S,2S)-3-(cyclopropanec...)
Show SMILES CC(=O)N[C@@H]1[C@@H](O)C=C(O[C@H]1[C@@H](O)[C@@H](O)CNC(=O)C1CC1)C(O)=O
Show InChI InChI=1S/C15H22N2O8/c1-6(18)17-11-8(19)4-10(15(23)24)25-13(11)12(21)9(20)5-16-14(22)7-2-3-7/h4,7-9,11-13,19-21H,2-3,5H2,1H3,(H,16,22)(H,17,18)(H,23,24)/t8-,9-,11+,12-,13+/m0/s1
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n/an/a 8.25E+5n/an/an/an/an/an/a



Gifu University

Curated by ChEMBL


Assay Description
Inhibition of human NEU4 expressed in HEK293 cells


Bioorg Med Chem Lett 18: 532-7 (2008)

More data for this
Ligand-Target Pair
Sialidase 4


(Homo sapiens)
BDBM50229631
PNG
((4S,5R,6R)-5-acetamido-6-((1S,2S)-3-butyramido-1,2...)
Show SMILES CCCC(=O)NC[C@H](O)[C@H](O)[C@@H]1OC(=C[C@H](O)[C@H]1NC(C)=O)C(O)=O
Show InChI InChI=1S/C15H24N2O8/c1-3-4-11(21)16-6-9(20)13(22)14-12(17-7(2)18)8(19)5-10(25-14)15(23)24/h5,8-9,12-14,19-20,22H,3-4,6H2,1-2H3,(H,16,21)(H,17,18)(H,23,24)/t8-,9-,12+,13-,14+/m0/s1
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n/an/a 9.23E+5n/an/an/an/an/an/a



Gifu University

Curated by ChEMBL


Assay Description
Inhibition of human NEU4 expressed in HEK293 cells


Bioorg Med Chem Lett 18: 532-7 (2008)

More data for this
Ligand-Target Pair
Sialidase 4


(Homo sapiens)
BDBM50343686
PNG
((3S,4R,5R)-4-acetamido-5-(pentan-3-yloxy)-3-(4-phe...)
Show SMILES CCC(CC)O[C@@H]1CC(=C[C@@H]([C@H]1NC(C)=O)n1cc(CCc2ccccc2)nn1)C(O)=O
Show InChI InChI=1S/C24H32N4O4/c1-4-20(5-2)32-22-14-18(24(30)31)13-21(23(22)25-16(3)29)28-15-19(26-27-28)12-11-17-9-7-6-8-10-17/h6-10,13,15,20-23H,4-5,11-12,14H2,1-3H3,(H,25,29)(H,30,31)/t21-,22+,23+/m0/s1
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n/an/a>1.00E+6n/an/an/an/an/an/a



University of Alberta

Curated by ChEMBL


Assay Description
Inhibition of human NEU4 using 4MU-NA as substrate after 1 hr by fluorescence assay


Bioorg Med Chem 19: 2817-22 (2011)

More data for this
Ligand-Target Pair
Sialidase 4


(Homo sapiens)
BDBM50343685
PNG
((3S,4R,5R)-4-Acetamido-5-(1-ethylpropoxy)-3-[4-(1-...)
Show SMILES CCC(CC)O[C@@H]1CC(=C[C@@H]([C@H]1NC(C)=O)n1cc(nn1)C(C)(C)O)C(O)=O
Show InChI InChI=1S/C19H30N4O5/c1-6-13(7-2)28-15-9-12(18(25)26)8-14(17(15)20-11(3)24)23-10-16(21-22-23)19(4,5)27/h8,10,13-15,17,27H,6-7,9H2,1-5H3,(H,20,24)(H,25,26)/t14-,15+,17+/m0/s1
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n/an/a>1.00E+6n/an/an/an/an/an/a



University of Alberta

Curated by ChEMBL


Assay Description
Inhibition of human NEU4 using 4MU-NA as substrate after 1 hr by fluorescence assay


Bioorg Med Chem 19: 2817-22 (2011)

More data for this
Ligand-Target Pair
Sialidase 4


(Homo sapiens)
BDBM50343684
PNG
((3S,4R,5R)-4-Acetamido-5-(1-ethyl-propoxy)-3-[4-(1...)
Show SMILES CCC(CC)O[C@@H]1CC(=C[C@@H]([C@H]1NC(C)=O)n1cc(nn1)C(O)CC)C(O)=O
Show InChI InChI=1S/C19H30N4O5/c1-5-13(6-2)28-17-9-12(19(26)27)8-15(18(17)20-11(4)24)23-10-14(21-22-23)16(25)7-3/h8,10,13,15-18,25H,5-7,9H2,1-4H3,(H,20,24)(H,26,27)/t15-,16?,17+,18+/m0/s1
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n/an/a>1.00E+6n/an/an/an/an/an/a



University of Alberta

Curated by ChEMBL


Assay Description
Inhibition of human NEU4 using 4MU-NA as substrate after 1 hr by fluorescence assay


Bioorg Med Chem 19: 2817-22 (2011)

More data for this
Ligand-Target Pair
Sialidase 4


(Homo sapiens)
BDBM50343683
PNG
((3S,4R,5R)-4-Acetamido-5-(1-ethylpropoxy)-3-[4-(3-...)
Show SMILES CCC(CC)O[C@@H]1CC(=C[C@@H]([C@H]1NC(C)=O)n1cc(CCCO)nn1)C(O)=O
Show InChI InChI=1S/C19H30N4O5/c1-4-15(5-2)28-17-10-13(19(26)27)9-16(18(17)20-12(3)25)23-11-14(21-22-23)7-6-8-24/h9,11,15-18,24H,4-8,10H2,1-3H3,(H,20,25)(H,26,27)/t16-,17+,18+/m0/s1
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n/an/a>1.00E+6n/an/an/an/an/an/a



University of Alberta

Curated by ChEMBL


Assay Description
Inhibition of human NEU4 using 4MU-NA as substrate after 1 hr by fluorescence assay


Bioorg Med Chem 19: 2817-22 (2011)

More data for this
Ligand-Target Pair
Sialidase 4


(Homo sapiens)
BDBM50343682
PNG
(((1S,5R,6R)-6-acetamido-3-carboxy-5-(pentan-3-ylox...)
Show SMILES CCC(CC)O[C@@H]1CC(=C[C@H](N=C(N)N)[C@H]1NC(C)=O)C(O)=O
Show InChI InChI=1S/C15H26N4O4/c1-4-10(5-2)23-12-7-9(14(21)22)6-11(19-15(16)17)13(12)18-8(3)20/h6,10-13H,4-5,7H2,1-3H3,(H,18,20)(H,21,22)(H4,16,17,19)/t11-,12+,13+/m0/s1
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n/an/a>1.00E+6n/an/an/an/an/an/a



University of Alberta

Curated by ChEMBL


Assay Description
Inhibition of human NEU4 using 4MU-NA as substrate after 1 hr by fluorescence assay


Bioorg Med Chem 19: 2817-22 (2011)

More data for this
Ligand-Target Pair
Sialidase 4


(Homo sapiens)
BDBM50343681
PNG
((3S,4R,5R)-4-Acetamido-3-amino-5-(1-ethylpropoxy)c...)
Show SMILES CCC(CC)O[C@@H]1CC(=C[C@H](N)[C@H]1NC(C)=O)C(O)=O
Show InChI InChI=1S/C14H24N2O4/c1-4-10(5-2)20-12-7-9(14(18)19)6-11(15)13(12)16-8(3)17/h6,10-13H,4-5,7,15H2,1-3H3,(H,16,17)(H,18,19)/t11-,12+,13+/m0/s1
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n/an/a>1.00E+6n/an/an/an/an/an/a



University of Alberta

Curated by ChEMBL


Assay Description
Inhibition of human NEU4 using 4MU-NA as substrate after 1 hr by fluorescence assay


Bioorg Med Chem 19: 2817-22 (2011)

More data for this
Ligand-Target Pair
Sialidase 4


(Homo sapiens)
BDBM50343680
PNG
((4R,5R)-4-acetamido-5-(pentan-3-yloxy)-3-(4-phenet...)
Show SMILES CCC(CC)O[C@@H]1CC(C=C([C@H]1NC(C)=O)n1cc(CCc2ccccc2)nn1)C(O)=O
Show InChI InChI=1S/C24H32N4O4/c1-4-20(5-2)32-22-14-18(24(30)31)13-21(23(22)25-16(3)29)28-15-19(26-27-28)12-11-17-9-7-6-8-10-17/h6-10,13,15,18,20,22-23H,4-5,11-12,14H2,1-3H3,(H,25,29)(H,30,31)/t18?,22-,23-/m1/s1
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n/an/a>1.00E+6n/an/an/an/an/an/a



University of Alberta

Curated by ChEMBL


Assay Description
Inhibition of human NEU4 using 4MU-NA as substrate after 1 hr by fluorescence assay


Bioorg Med Chem 19: 2817-22 (2011)

More data for this
Ligand-Target Pair
Sialidase 4


(Homo sapiens)
BDBM50229633
PNG
((4S,5R,6R)-5-acetamido-6-((1S,2S)-1,2-dihydroxy-3-...)
Show SMILES CCCCC(=O)NC[C@H](O)[C@H](O)[C@@H]1OC(=C[C@H](O)[C@H]1NC(C)=O)C(O)=O
Show InChI InChI=1S/C16H26N2O8/c1-3-4-5-12(22)17-7-10(21)14(23)15-13(18-8(2)19)9(20)6-11(26-15)16(24)25/h6,9-10,13-15,20-21,23H,3-5,7H2,1-2H3,(H,17,22)(H,18,19)(H,24,25)/t9-,10-,13+,14-,15+/m0/s1
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n/an/a>1.00E+6n/an/an/an/an/an/a



Gifu University

Curated by ChEMBL


Assay Description
Inhibition of human NEU4 expressed in HEK293 cells


Bioorg Med Chem Lett 18: 532-7 (2008)

More data for this
Ligand-Target Pair
Sialidase 4


(Homo sapiens)
BDBM50229628
PNG
((4S,5R,6R)-5-acetamido-6-((1S,2S)-1,2-dihydroxy-3-...)
Show SMILES CCC(C)CC(=O)NC[C@H](O)[C@H](O)[C@@H]1OC(=C[C@H](O)[C@H]1NC(C)=O)C(O)=O
Show InChI InChI=1S/C17H28N2O8/c1-4-8(2)5-13(23)18-7-11(22)15(24)16-14(19-9(3)20)10(21)6-12(27-16)17(25)26/h6,8,10-11,14-16,21-22,24H,4-5,7H2,1-3H3,(H,18,23)(H,19,20)(H,25,26)/t8?,10-,11-,14+,15-,16+/m0/s1
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n/an/a>1.00E+6n/an/an/an/an/an/a



Gifu University

Curated by ChEMBL


Assay Description
Inhibition of human NEU4 expressed in HEK293 cells


Bioorg Med Chem Lett 18: 532-7 (2008)

More data for this
Ligand-Target Pair
Sialidase 4


(Homo sapiens)
BDBM50229626
PNG
((4S,5R,6R)-5-acetamido-6-((1S,2S)-3-(cyclopentanec...)
Show SMILES CC(=O)N[C@@H]1[C@@H](O)C=C(O[C@H]1[C@@H](O)[C@@H](O)CNC(=O)C1CCCC1)C(O)=O
Show InChI InChI=1S/C17H26N2O8/c1-8(20)19-13-10(21)6-12(17(25)26)27-15(13)14(23)11(22)7-18-16(24)9-4-2-3-5-9/h6,9-11,13-15,21-23H,2-5,7H2,1H3,(H,18,24)(H,19,20)(H,25,26)/t10-,11-,13+,14-,15+/m0/s1
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n/an/a>1.00E+6n/an/an/an/an/an/a



Gifu University

Curated by ChEMBL


Assay Description
Inhibition of human NEU4 expressed in HEK293 cells


Bioorg Med Chem Lett 18: 532-7 (2008)

More data for this
Ligand-Target Pair
Sialidase 4


(Homo sapiens)
BDBM50229629
PNG
((4S,5R,6R)-5-acetamido-6-((1S,2S)-1,2-dihydroxy-3-...)
Show SMILES CC(C)CC(=O)NC[C@H](O)[C@H](O)[C@@H]1OC(=C[C@H](O)[C@H]1NC(C)=O)C(O)=O
Show InChI InChI=1S/C16H26N2O8/c1-7(2)4-12(22)17-6-10(21)14(23)15-13(18-8(3)19)9(20)5-11(26-15)16(24)25/h5,7,9-10,13-15,20-21,23H,4,6H2,1-3H3,(H,17,22)(H,18,19)(H,24,25)/t9-,10-,13+,14-,15+/m0/s1
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n/an/a>1.00E+6n/an/an/an/an/an/a



Gifu University

Curated by ChEMBL


Assay Description
Inhibition of human NEU4 expressed in HEK293 cells


Bioorg Med Chem Lett 18: 532-7 (2008)

More data for this
Ligand-Target Pair
Sialidase 4


(Homo sapiens)
BDBM50229627
PNG
((4S,5R,6R)-5-acetamido-6-((1S,2S)-1,2-dihydroxy-3-...)
Show SMILES CC(=O)N[C@@H]1[C@@H](O)C=C(O[C@H]1[C@@H](O)[C@@H](O)CNC(=O)C(C)(C)C)C(O)=O
Show InChI InChI=1S/C16H26N2O8/c1-7(19)18-11-8(20)5-10(14(23)24)26-13(11)12(22)9(21)6-17-15(25)16(2,3)4/h5,8-9,11-13,20-22H,6H2,1-4H3,(H,17,25)(H,18,19)(H,23,24)/t8-,9-,11+,12-,13+/m0/s1
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n/an/a>1.00E+6n/an/an/an/an/an/a



Gifu University

Curated by ChEMBL


Assay Description
Inhibition of human NEU4 expressed in HEK293 cells


Bioorg Med Chem Lett 18: 532-7 (2008)

More data for this
Ligand-Target Pair
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