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Found 20 hits Enz. Inhib. hit(s) with Target = 'Sodium/iodide cotransporter' AND taxid = 10116   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sodium/iodide cotransporter


(Rattus norvegicus)
BDBM50430695
PNG
(CHEMBL2333516)
Show SMILES COc1cccc(COC(=O)C2=C(C)N(C)C(=O)N(C)C2c2ccco2)c1
Show InChI InChI=1S/C20H22N2O5/c1-13-17(19(23)27-12-14-7-5-8-15(11-14)25-4)18(16-9-6-10-26-16)22(3)20(24)21(13)2/h5-11,18H,12H2,1-4H3
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n/an/a 0.0650n/an/an/an/an/an/a



Institut de Biologie et de Technologies de Saclay (iBiTecS)

Curated by ChEMBL


Assay Description
inhibition of sodium iodide symporter in rat FRTL5 cells after 1 hr by arsenic/cerium titration assay


Eur J Med Chem 62: 722-7 (2013)

More data for this
Ligand-Target Pair
Sodium/iodide cotransporter


(Rattus norvegicus)
BDBM50430697
PNG
(CHEMBL2333514)
Show SMILES COc1cccc(COC(=O)C2C(NC(=O)N=C2C)c2ccco2)c1
Show InChI InChI=1S/C18H18N2O5/c1-11-15(16(20-18(22)19-11)14-7-4-8-24-14)17(21)25-10-12-5-3-6-13(9-12)23-2/h3-9,15-16H,10H2,1-2H3,(H,20,22)
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n/an/a 0.570n/an/an/an/an/an/a



Institut de Biologie et de Technologies de Saclay (iBiTecS)

Curated by ChEMBL


Assay Description
inhibition of sodium iodide symporter in rat FRTL5 cells after 1 hr by arsenic/cerium titration assay


Eur J Med Chem 62: 722-7 (2013)

More data for this
Ligand-Target Pair
Sodium/iodide cotransporter


(Rattus norvegicus)
BDBM50430685
PNG
(CHEMBL2333509)
Show SMILES CN1[C@H](c2ccco2)C(C(=O)OCc2ccc3OCOc3c2)=C(C)N(C)C1=O
Show InChI InChI=1S/C20H20N2O6/c1-12-17(18(15-5-4-8-25-15)22(3)20(24)21(12)2)19(23)26-10-13-6-7-14-16(9-13)28-11-27-14/h4-9,18H,10-11H2,1-3H3/t18-/m1/s1
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n/an/a 0.700n/an/an/an/an/an/a



Institut de Biologie et de Technologies de Saclay (iBiTecS)

Curated by ChEMBL


Assay Description
inhibition of sodium iodide symporter in rat FRTL5 cells after 1 hr by arsenic/cerium titration assay


Eur J Med Chem 62: 722-7 (2013)

More data for this
Ligand-Target Pair
Sodium/iodide cotransporter


(Rattus norvegicus)
BDBM50430685
PNG
(CHEMBL2333509)
Show SMILES CN1[C@H](c2ccco2)C(C(=O)OCc2ccc3OCOc3c2)=C(C)N(C)C1=O
Show InChI InChI=1S/C20H20N2O6/c1-12-17(18(15-5-4-8-25-15)22(3)20(24)21(12)2)19(23)26-10-13-6-7-14-16(9-13)28-11-27-14/h4-9,18H,10-11H2,1-3H3/t18-/m1/s1
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n/an/a 0.850n/an/an/an/an/an/a



Institut de Biologie et de Technologies de Saclay (iBiTecS)

Curated by ChEMBL


Assay Description
inhibition of sodium iodide symporter in rat FRTL5 cells after 1 hr by arsenic/cerium titration assay


Eur J Med Chem 62: 722-7 (2013)

More data for this
Ligand-Target Pair
Sodium/iodide cotransporter


(Rattus norvegicus)
BDBM50430698
PNG
(CHEMBL2333513)
Show SMILES COc1ccc(COC(=O)C2=C(C)N(C)C(=O)N(C)C2c2ccco2)cc1
Show InChI InChI=1S/C20H22N2O5/c1-13-17(19(23)27-12-14-7-9-15(25-4)10-8-14)18(16-6-5-11-26-16)22(3)20(24)21(13)2/h5-11,18H,12H2,1-4H3
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n/an/a 1.60n/an/an/an/an/an/a



Institut de Biologie et de Technologies de Saclay (iBiTecS)

Curated by ChEMBL


Assay Description
inhibition of sodium iodide symporter in rat FRTL5 cells after 1 hr by arsenic/cerium titration assay


Eur J Med Chem 62: 722-7 (2013)

More data for this
Ligand-Target Pair
Sodium/iodide cotransporter


(Rattus norvegicus)
BDBM50430684
PNG
(CHEMBL2333507)
Show SMILES COc1ccc(COC(=O)C2[C@H](NC(=O)N=C2C)c2ccco2)cc1
Show InChI InChI=1S/C18H18N2O5/c1-11-15(16(20-18(22)19-11)14-4-3-9-24-14)17(21)25-10-12-5-7-13(23-2)8-6-12/h3-9,15-16H,10H2,1-2H3,(H,20,22)/t15?,16-/m1/s1
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n/an/a 3.20n/an/an/an/an/an/a



Institut de Biologie et de Technologies de Saclay (iBiTecS)

Curated by ChEMBL


Assay Description
inhibition of sodium iodide symporter in rat FRTL5 cells after 1 hr by arsenic/cerium titration assay


Eur J Med Chem 62: 722-7 (2013)

More data for this
Ligand-Target Pair
Sodium/iodide cotransporter


(Rattus norvegicus)
BDBM50430691
PNG
(CHEMBL2333502)
Show SMILES CC1=NC(=O)NC(C1C(=O)OCc1ccc2OCOc2c1)c1ccco1
Show InChI InChI=1S/C18H16N2O6/c1-10-15(16(20-18(22)19-10)13-3-2-6-23-13)17(21)24-8-11-4-5-12-14(7-11)26-9-25-12/h2-7,15-16H,8-9H2,1H3,(H,20,22)
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n/an/a 4n/an/an/an/an/an/a



Institut de Biologie et de Technologies de Saclay (iBiTecS)

Curated by ChEMBL


Assay Description
inhibition of sodium iodide symporter in rat FRTL5 cells after 1 hr by arsenic/cerium titration assay


Eur J Med Chem 62: 722-7 (2013)

More data for this
Ligand-Target Pair
Sodium/iodide cotransporter


(Rattus norvegicus)
BDBM50430692
PNG
(CHEMBL2333501)
Show SMILES COc1ccc(COC(=O)C2=C(C)N(C)C(=O)N(C)C2c2ccco2)cc1OC
Show InChI InChI=1S/C21H24N2O6/c1-13-18(19(16-7-6-10-28-16)23(3)21(25)22(13)2)20(24)29-12-14-8-9-15(26-4)17(11-14)27-5/h6-11,19H,12H2,1-5H3
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n/an/a 6.5n/an/an/an/an/an/a



Institut de Biologie et de Technologies de Saclay (iBiTecS)

Curated by ChEMBL


Assay Description
inhibition of sodium iodide symporter in rat FRTL5 cells after 1 hr by arsenic/cerium titration assay


Eur J Med Chem 62: 722-7 (2013)

More data for this
Ligand-Target Pair
Sodium/iodide cotransporter


(Rattus norvegicus)
BDBM50430689
PNG
(CHEMBL2333505)
Show SMILES COc1ccc(COC(=O)C2[C@H](NC(=O)N=C2C)c2ccccc2)cc1
Show InChI InChI=1S/C20H20N2O4/c1-13-17(18(22-20(24)21-13)15-6-4-3-5-7-15)19(23)26-12-14-8-10-16(25-2)11-9-14/h3-11,17-18H,12H2,1-2H3,(H,22,24)/t17?,18-/m1/s1
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n/an/a 70n/an/an/an/an/an/a



Institut de Biologie et de Technologies de Saclay (iBiTecS)

Curated by ChEMBL


Assay Description
inhibition of sodium iodide symporter in rat FRTL5 cells after 1 hr by arsenic/cerium titration assay


Eur J Med Chem 62: 722-7 (2013)

More data for this
Ligand-Target Pair
Sodium/iodide cotransporter


(Rattus norvegicus)
BDBM50430690
PNG
(CHEMBL2333503)
Show SMILES CN1C(=O)NC(c2ccco2)C(C(=O)OCc2ccc3OCOc3c2)=C1C
Show InChI InChI=1S/C19H18N2O6/c1-11-16(17(14-4-3-7-24-14)20-19(23)21(11)2)18(22)25-9-12-5-6-13-15(8-12)27-10-26-13/h3-8,17H,9-10H2,1-2H3,(H,20,23)
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n/an/a 73n/an/an/an/an/an/a



Institut de Biologie et de Technologies de Saclay (iBiTecS)

Curated by ChEMBL


Assay Description
inhibition of sodium iodide symporter in rat FRTL5 cells after 1 hr by arsenic/cerium titration assay


Eur J Med Chem 62: 722-7 (2013)

More data for this
Ligand-Target Pair
Sodium/iodide cotransporter


(Rattus norvegicus)
BDBM50430696
PNG
(CHEMBL2333515)
Show SMILES COc1cccc(COC(=O)C2=C(C)N(C)C(=O)NC2c2ccco2)c1
Show InChI InChI=1S/C19H20N2O5/c1-12-16(17(15-8-5-9-25-15)20-19(23)21(12)2)18(22)26-11-13-6-4-7-14(10-13)24-3/h4-10,17H,11H2,1-3H3,(H,20,23)
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n/an/a 75n/an/an/an/an/an/a



Institut de Biologie et de Technologies de Saclay (iBiTecS)

Curated by ChEMBL


Assay Description
inhibition of sodium iodide symporter in rat FRTL5 cells after 1 hr by arsenic/cerium titration assay


Eur J Med Chem 62: 722-7 (2013)

More data for this
Ligand-Target Pair
Sodium/iodide cotransporter


(Rattus norvegicus)
BDBM50430686
PNG
(CHEMBL2333506)
Show SMILES COc1ccc(COC(=O)C2[C@@H](NC(=O)N=C2C)c2ccccc2)cc1
Show InChI InChI=1S/C20H20N2O4/c1-13-17(18(22-20(24)21-13)15-6-4-3-5-7-15)19(23)26-12-14-8-10-16(25-2)11-9-14/h3-11,17-18H,12H2,1-2H3,(H,22,24)/t17?,18-/m0/s1
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n/an/a 89n/an/an/an/an/an/a



Institut de Biologie et de Technologies de Saclay (iBiTecS)

Curated by ChEMBL


Assay Description
inhibition of sodium iodide symporter in rat FRTL5 cells after 1 hr by arsenic/cerium titration assay


Eur J Med Chem 62: 722-7 (2013)

More data for this
Ligand-Target Pair
Sodium/iodide cotransporter


(Rattus norvegicus)
BDBM50430699
PNG
(CHEMBL2333512)
Show SMILES COc1ccc(COC(=O)C2=C(C)N(C)C(=O)NC2c2ccco2)cc1
Show InChI InChI=1S/C19H20N2O5/c1-12-16(17(15-5-4-10-25-15)20-19(23)21(12)2)18(22)26-11-13-6-8-14(24-3)9-7-13/h4-10,17H,11H2,1-3H3,(H,20,23)
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n/an/a 90n/an/an/an/an/an/a



Institut de Biologie et de Technologies de Saclay (iBiTecS)

Curated by ChEMBL


Assay Description
inhibition of sodium iodide symporter in rat FRTL5 cells after 1 hr by arsenic/cerium titration assay


Eur J Med Chem 62: 722-7 (2013)

More data for this
Ligand-Target Pair
Sodium/iodide cotransporter


(Rattus norvegicus)
BDBM36131
PNG
(perchlorate | sodium perchlorate)
Show SMILES [O-][Cl](=O)(=O)=O
Show InChI InChI=1S/ClHO4/c2-1(3,4)5/h(H,2,3,4,5)/p-1
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n/an/a 100n/an/an/an/an/an/a



Institut de Biologie et de Technologies de Saclay (iBiTecS)

Curated by ChEMBL


Assay Description
inhibition of sodium iodide symporter in rat FRTL5 cells after 1 hr by arsenic/cerium titration assay


Eur J Med Chem 62: 722-7 (2013)

More data for this
Ligand-Target Pair
Sodium/iodide cotransporter


(Rattus norvegicus)
BDBM50430694
PNG
(CHEMBL2333517)
Show SMILES COc1ccc(COC(=O)C2C(NC(=O)N=C2C)c2ccco2)cc1OC
Show InChI InChI=1S/C19H20N2O6/c1-11-16(17(21-19(23)20-11)14-5-4-8-26-14)18(22)27-10-12-6-7-13(24-2)15(9-12)25-3/h4-9,16-17H,10H2,1-3H3,(H,21,23)
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n/an/a 400n/an/an/an/an/an/a



Institut de Biologie et de Technologies de Saclay (iBiTecS)

Curated by ChEMBL


Assay Description
inhibition of sodium iodide symporter in rat FRTL5 cells after 1 hr by arsenic/cerium titration assay


Eur J Med Chem 62: 722-7 (2013)

More data for this
Ligand-Target Pair
Sodium/iodide cotransporter


(Rattus norvegicus)
BDBM50430684
PNG
(CHEMBL2333507)
Show SMILES COc1ccc(COC(=O)C2[C@H](NC(=O)N=C2C)c2ccco2)cc1
Show InChI InChI=1S/C18H18N2O5/c1-11-15(16(20-18(22)19-11)14-4-3-9-24-14)17(21)25-10-12-5-7-13(23-2)8-6-12/h3-9,15-16H,10H2,1-2H3,(H,20,22)/t15?,16-/m1/s1
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n/an/a 630n/an/an/an/an/an/a



Institut de Biologie et de Technologies de Saclay (iBiTecS)

Curated by ChEMBL


Assay Description
inhibition of sodium iodide symporter in rat FRTL5 cells after 1 hr by arsenic/cerium titration assay


Eur J Med Chem 62: 722-7 (2013)

More data for this
Ligand-Target Pair
Sodium/iodide cotransporter


(Rattus norvegicus)
BDBM50430688
PNG
(CHEMBL2333510)
Show SMILES CN1[C@@H](c2ccco2)C(C(=O)OCc2ccc3OCOc3c2)=C(C)N(C)C1=O
Show InChI InChI=1S/C20H20N2O6/c1-12-17(18(15-5-4-8-25-15)22(3)20(24)21(12)2)19(23)26-10-13-6-7-14-16(9-13)28-11-27-14/h4-9,18H,10-11H2,1-3H3/t18-/m0/s1
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n/an/a 630n/an/an/an/an/an/a



Institut de Biologie et de Technologies de Saclay (iBiTecS)

Curated by ChEMBL


Assay Description
inhibition of sodium iodide symporter in rat FRTL5 cells after 1 hr by arsenic/cerium titration assay


Eur J Med Chem 62: 722-7 (2013)

More data for this
Ligand-Target Pair
Sodium/iodide cotransporter


(Rattus norvegicus)
BDBM50430693
PNG
(CHEMBL2333518)
Show SMILES COc1ccc(COC(=O)C2=C(C)N(C)C(=O)NC2c2ccco2)cc1OC
Show InChI InChI=1S/C20H22N2O6/c1-12-17(18(15-6-5-9-27-15)21-20(24)22(12)2)19(23)28-11-13-7-8-14(25-3)16(10-13)26-4/h5-10,18H,11H2,1-4H3,(H,21,24)
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n/an/a 1.00E+3n/an/an/an/an/an/a



Institut de Biologie et de Technologies de Saclay (iBiTecS)

Curated by ChEMBL


Assay Description
inhibition of sodium iodide symporter in rat FRTL5 cells after 1 hr by arsenic/cerium titration assay


Eur J Med Chem 62: 722-7 (2013)

More data for this
Ligand-Target Pair
Sodium/iodide cotransporter


(Rattus norvegicus)
BDBM50430686
PNG
(CHEMBL2333506)
Show SMILES COc1ccc(COC(=O)C2[C@@H](NC(=O)N=C2C)c2ccccc2)cc1
Show InChI InChI=1S/C20H20N2O4/c1-13-17(18(22-20(24)21-13)15-6-4-3-5-7-15)19(23)26-12-14-8-10-16(25-2)11-9-14/h3-11,17-18H,12H2,1-2H3,(H,22,24)/t17?,18-/m0/s1
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n/an/a 1.50E+3n/an/an/an/an/an/a



Institut de Biologie et de Technologies de Saclay (iBiTecS)

Curated by ChEMBL


Assay Description
inhibition of sodium iodide symporter in rat FRTL5 cells after 1 hr by arsenic/cerium titration assay


Eur J Med Chem 62: 722-7 (2013)

More data for this
Ligand-Target Pair
Sodium/iodide cotransporter


(Rattus norvegicus)
BDBM50430687
PNG
(CHEMBL2333508)
Show SMILES COc1ccc(COC(=O)C2[C@@H](NC(=O)N=C2C)c2ccco2)cc1
Show InChI InChI=1S/C18H18N2O5/c1-11-15(16(20-18(22)19-11)14-4-3-9-24-14)17(21)25-10-12-5-7-13(23-2)8-6-12/h3-9,15-16H,10H2,1-2H3,(H,20,22)/t15?,16-/m0/s1
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n/an/a 1.40E+4n/an/an/an/an/an/a



Institut de Biologie et de Technologies de Saclay (iBiTecS)

Curated by ChEMBL


Assay Description
inhibition of sodium iodide symporter in rat FRTL5 cells after 1 hr by arsenic/cerium titration assay


Eur J Med Chem 62: 722-7 (2013)

More data for this
Ligand-Target Pair