BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 455 hits Enz. Inhib. hit(s) with Target = 'Solute carrier family 22 member 1' AND taxid = 9606   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Solute carrier family 22 member 11


(Homo sapiens)
BDBM82898
PNG
((6R,7R)-3-(acetoxymethyl)-8-keto-7-[[2-(2-thienyl)...)
Show SMILES CC(=O)OCC1=C(N2[C@H](SC1)[C@H](NC(=O)Cc1cccs1)C2=O)C(O)=O
Show InChI InChI=1S/C16H16N2O6S2/c1-8(19)24-6-9-7-26-15-12(14(21)18(15)13(9)16(22)23)17-11(20)5-10-3-2-4-25-10/h2-4,12,15H,5-7H2,1H3,(H,17,20)(H,22,23)/t12-,15-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

DrugBank
KEGG
PC cid
PC sid
PDB
UniChem

Similars

AffyNet 
PubMed
200n/an/an/an/an/an/an/an/a



Kyorin University School of Medicine

Curated by ChEMBL


Assay Description
TP_TRANSPORTER: inhibition of Estrone sulfate uptake in OAT4-expressing S2 cells


Eur J Pharmacol 438: 137-42 (2002)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 11


(Homo sapiens)
BDBM50350468
PNG
(CEFAMANDOLE)
Show SMILES Cn1nnnc1SCC1=C(N2[C@H](SC1)[C@H](NC(=O)[C@H](O)c1ccccc1)C2=O)C(O)=O
Show InChI InChI=1S/C18H18N6O5S2/c1-23-18(20-21-22-23)31-8-10-7-30-16-11(15(27)24(16)12(10)17(28)29)19-14(26)13(25)9-5-3-2-4-6-9/h2-6,11,13,16,25H,7-8H2,1H3,(H,19,26)(H,28,29)/t11-,13-,16-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
UniChem

Patents


Similars

AffyNet 
PubMed
1.14E+3n/an/an/an/an/an/an/an/a



Kyorin University School of Medicine

Curated by ChEMBL


Assay Description
TP_TRANSPORTER: inhibition of Estrone sulfate uptake in OAT4-expressing S2 cells


Eur J Pharmacol 438: 137-42 (2002)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 11


(Homo sapiens)
BDBM50370587
PNG
(CEFAZOLIN)
Show SMILES Cc1nnc(SCC2=C(N3[C@H](SC2)[C@H](NC(=O)Cn2cnnn2)C3=O)C(O)=O)s1
Show InChI InChI=1S/C14H14N8O4S3/c1-6-17-18-14(29-6)28-4-7-3-27-12-9(11(24)22(12)10(7)13(25)26)16-8(23)2-21-5-15-19-20-21/h5,9,12H,2-4H2,1H3,(H,16,23)(H,25,26)/t9-,12-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

DrugBank
KEGG
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
1.74E+3n/an/an/an/an/an/an/an/a



Kyorin University School of Medicine

Curated by ChEMBL


Assay Description
TP_TRANSPORTER: inhibition of Estrone sulfate uptake in OAT4-expressing S2 cells


Eur J Pharmacol 438: 137-42 (2002)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 11


(Homo sapiens)
BDBM50049707
PNG
((6R,7R)-7-{2-(2-Amino-thiazol-4-yl)-2-[(Z)-methoxy...)
Show SMILES CO\N=C(/C(=O)N[C@H]1[C@H]2SCC(CSc3nc(=O)c(=O)[nH]n3C)=C(N2C1=O)C(O)=O)c1csc(N)n1
Show InChI InChI=1S/C18H18N8O7S3/c1-25-18(22-12(28)13(29)23-25)36-4-6-3-34-15-9(14(30)26(15)10(6)16(31)32)21-11(27)8(24-33-2)7-5-35-17(19)20-7/h5,9,15H,3-4H2,1-2H3,(H2,19,20)(H,21,27)(H,23,29)(H,31,32)/b24-8-/t9-,15-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
KEGG
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
PubMed
2.38E+3n/an/an/an/an/an/an/an/a



Kyorin University School of Medicine

Curated by ChEMBL


Assay Description
TP_TRANSPORTER: inhibition of Estrone sulfate uptake in OAT4-expressing S2 cells


Eur J Pharmacol 438: 137-42 (2002)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 11


(Homo sapiens)
BDBM50390999
PNG
(CEFOPERAZONE)
Show SMILES CCN1CCN(C(=O)N[C@@H](C(=O)N[C@H]2[C@H]3SCC(CSc4nnnn4C)=C(N3C2=O)C(O)=O)c2ccc(O)cc2)C(=O)C1=O
Show InChI InChI=1S/C25H27N9O8S2/c1-3-32-8-9-33(21(39)20(32)38)24(42)27-15(12-4-6-14(35)7-5-12)18(36)26-16-19(37)34-17(23(40)41)13(10-43-22(16)34)11-44-25-28-29-30-31(25)2/h4-7,15-16,22,35H,3,8-11H2,1-2H3,(H,26,36)(H,27,42)(H,40,41)/t15-,16-,22-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

KEGG
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
2.80E+3n/an/an/an/an/an/an/an/a



Kyorin University School of Medicine

Curated by ChEMBL


Assay Description
TP_TRANSPORTER: inhibition of Estrone sulfate uptake in OAT4-expressing S2 cells


Eur J Pharmacol 438: 137-42 (2002)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 11


(Homo sapiens)
BDBM50350473
PNG
(Aliporina | CEFALORIDINE)
Show SMILES [O-]C(=O)C1=C(C[n+]2ccccc2)CS[C@@H]2[C@@H](NC(=O)Cc3cccs3)C(=O)N12
Show InChI InChI=1S/C19H17N3O4S2/c23-14(9-13-5-4-8-27-13)20-15-17(24)22-16(19(25)26)12(11-28-18(15)22)10-21-6-2-1-3-7-21/h1-8,15,18H,9-11H2,(H-,20,23,25,26)/t15-,18+/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
AffyNet 
PubMed
3.63E+3n/an/an/an/an/an/an/an/a



Kyorin University School of Medicine

Curated by ChEMBL


Assay Description
TP_TRANSPORTER: inhibition of Estrone sulfate uptake in OAT4-expressing S2 cells


Eur J Pharmacol 438: 137-42 (2002)

More data for this
Ligand-Target Pair
Uric Acid Transporter 1 (URAT1)


(Homo sapiens (Human))
BDBM26658
PNG
(2-(2,4-dihydroxyphenyl)-3,5,7-trihydroxy-1-benzopy...)
Show SMILES Oc1ccc(c(O)c1)-c1oc2cc(O)cc(O)c2c(=O)c1O
Show InChI InChI=1S/C15H10O7/c16-6-1-2-8(9(18)3-6)15-14(21)13(20)12-10(19)4-7(17)5-11(12)22-15/h1-5,16-19,21H
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
KEGG
PC cid
PC sid
PDB
UniChem

Patents


Similars

AffyNet 
Article
PubMed
5.74E+3n/an/an/an/an/an/an/an/a



The Chinese University of Hong Kong

Curated by ChEMBL


Assay Description
Inhibition of human URAT1-mediated urate uptake in HEK293 cells by competitive inhibition assay


Citation and Details
More data for this
Ligand-Target Pair
Solute carrier family 22 member 11


(Homo sapiens)
BDBM50335523
PNG
((6R,7R)-3-(acetoxymethyl)-7-(2-(2-aminothiazol-4-y...)
Show SMILES CO\N=C(\C(=O)N[C@H]1[C@H]2SCC(COC(C)=O)=C(N2C1=O)C(O)=O)c1csc(N)n1
Show InChI InChI=1S/C16H17N5O7S2/c1-6(22)28-3-7-4-29-14-10(13(24)21(14)11(7)15(25)26)19-12(23)9(20-27-2)8-5-30-16(17)18-8/h5,10,14H,3-4H2,1-2H3,(H2,17,18)(H,19,23)(H,25,26)/b20-9+/t10-,14-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
PubMed
6.15E+3n/an/an/an/an/an/an/an/a



Kyorin University School of Medicine

Curated by ChEMBL


Assay Description
TP_TRANSPORTER: inhibition of Estrone sulfate uptake in OAT4-expressing S2 cells


Eur J Pharmacol 438: 137-42 (2002)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 11


(Homo sapiens)
BDBM50003019
PNG
(8-(Hexahydro-2,5-methano-pentalen-3a-yl)-1,3-dipro...)
Show SMILES CCCn1c2nc([nH]c2c(=O)n(CCC)c1=O)C12CC3CC1CC(C2)C3
Show InChI InChI=1S/C20H28N4O2/c1-3-5-23-16-15(17(25)24(6-4-2)19(23)26)21-18(22-16)20-10-12-7-13(11-20)9-14(20)8-12/h12-14H,3-11H2,1-2H3,(H,21,22)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
PubMed
2.07E+4n/an/an/an/an/an/an/an/a



Nagoya University School of Medicine

Curated by ChEMBL


Assay Description
TP_TRANSPORTER: inhibition of E1S uptake in OAT4-expressing S2 cells


J Pharmacol Exp Ther 301: 797-802 (2002)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 1


(Homo sapiens)
BDBM50416487
PNG
(CHEMBL1236196 | TETRABUTYLAMMONIUM)
Show SMILES CCCC[N+](CCCC)(CCCC)CCCC
Show InChI InChI=1S/C16H36N/c1-5-9-13-17(14-10-6-2,15-11-7-3)16-12-8-4/h5-16H2,1-4H3/q+1
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
PC cid
PC sid
PDB
UniChem

Similars

AffyNet 
PubMed
2.96E+4n/an/an/an/an/an/an/an/a



University of California

Curated by ChEMBL


Assay Description
TP_TRANSPORTER: inhibition of MPP+ uptake in Xenopus laevis oocytes


J Pharmacol Exp Ther 292: 1146-52 (2000)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 16


(Homo sapiens)
BDBM50037268
PNG
((-)-Carnitine | (-)-L-Carnitine | (3R)-3-hydroxy-4...)
Show SMILES C[N+](C)(C)C[C@H](O)CC([O-])=O
Show InChI InChI=1S/C7H15NO3/c1-8(2,3)5-6(9)4-7(10)11/h6,9H,4-5H2,1-3H3/t6-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
KEGG
PC cid
PC sid
UniChem

Patents

AffyNet 
Article
PubMed
3.00E+4n/an/an/an/an/an/an/an/a



Kyorin University

Curated by ChEMBL


Assay Description
TP_TRANSPORTER: inhibition of carnitine in Xenopus laevis oocytes


Citation and Details
More data for this
Ligand-Target Pair
Solute carrier family 22 member 11


(Homo sapiens)
BDBM50206509
PNG
(4-Dipropylsulfamoyl-benzoic acid | 4-Dipropylsulfa...)
Show SMILES CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(O)=O
Show InChI InChI=1S/C13H19NO4S/c1-3-9-14(10-4-2)19(17,18)12-7-5-11(6-8-12)13(15)16/h5-8H,3-4,9-10H2,1-2H3,(H,15,16)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
KEGG
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
PubMed
4.44E+4n/an/an/an/an/an/an/an/a



Kyorin University School of Medicine

Curated by ChEMBL


Assay Description
TP_TRANSPORTER: inhibition of Ochratoxin A uptake in OAT4-expressing S2 cells


Biochim Biophys Acta 1590: 64-75 (2002)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 11


(Homo sapiens)
BDBM50206509
PNG
(4-Dipropylsulfamoyl-benzoic acid | 4-Dipropylsulfa...)
Show SMILES CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(O)=O
Show InChI InChI=1S/C13H19NO4S/c1-3-9-14(10-4-2)19(17,18)12-7-5-11(6-8-12)13(15)16/h5-8H,3-4,9-10H2,1-2H3,(H,15,16)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
KEGG
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
PubMed
5.49E+4n/an/an/an/an/an/an/an/a



Nagoya University School of Medicine

Curated by ChEMBL


Assay Description
TP_TRANSPORTER: inhibition of E1S uptake in OAT4-expressing S2 cells


J Pharmacol Exp Ther 301: 797-802 (2002)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 1


(Homo sapiens)
BDBM50420179
PNG
(CHEMBL2074857)
Show SMILES CCC[N+](CCC)(CCC)CCC
Show InChI InChI=1S/C12H28N/c1-5-9-13(10-6-2,11-7-3)12-8-4/h5-12H2,1-4H3/q+1
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem
AffyNet 
PubMed
1.02E+5n/an/an/an/an/an/an/an/a



University of California

Curated by ChEMBL


Assay Description
TP_TRANSPORTER: inhibition of MPP+ uptake in Xenopus laevis oocytes


J Pharmacol Exp Ther 292: 1146-52 (2000)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 1


(Homo sapiens)
BDBM50248106
PNG
(CHEMBL461101 | ELTROMBOPAG)
Show SMILES Cc1[nH]n(-c2ccc(C)c(C)c2)c(=O)c1N=Nc1cccc(-c2cccc(c2)C(O)=O)c1O
Show InChI InChI=1S/C25H22N4O4/c1-14-10-11-19(12-15(14)2)29-24(31)22(16(3)28-29)27-26-21-9-5-8-20(23(21)30)17-6-4-7-18(13-17)25(32)33/h4-13,28,30H,1-3H3,(H,32,33)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
1.03E+5n/an/an/an/an/an/an/an/a



Kanazawa University

Curated by ChEMBL


Assay Description
Inhibition of OCT1-mediated [14C]tetraethylammonium uptake in human OCT1 expressing HEK293/PDZK1 cells by scintillation counting


Citation and Details
More data for this
Ligand-Target Pair
Solute carrier family 22 member 11


(Homo sapiens)
BDBM85245
PNG
(CAS_36322-90-4 | NSC_4856 | PIROXICAM | Piroxicam)
Show SMILES CN1C(C(=O)Nc2ccccn2)=C(O)c2ccccc2S1(=O)=O
Show InChI InChI=1S/C15H13N3O4S/c1-18-13(15(20)17-12-8-4-5-9-16-12)14(19)10-6-2-3-7-11(10)23(18,21)22/h2-9,19H,1H3,(H,16,17,20)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

DrugBank
KEGG
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
PubMed
1.08E+5n/an/an/an/an/an/an/an/a



Kyorin University School of Medicine

Curated by ChEMBL


Assay Description
TP_TRANSPORTER: inhibition of Ochratoxin A uptake in OAT4-expressing S2 cells


Biochim Biophys Acta 1590: 64-75 (2002)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 1


(Homo sapiens)
BDBM50149890
PNG
(CHEMBL9324 | tetraethylammonium)
Show SMILES CC[N+](CC)(CC)CC
Show InChI InChI=1S/C8H20N/c1-5-9(6-2,7-3)8-4/h5-8H2,1-4H3/q+1
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
PubMed
1.58E+5n/an/an/an/an/an/an/an/a



University of California

Curated by ChEMBL


Assay Description
TP_TRANSPORTER: inhibition of MPP+ uptake in Xenopus laevis oocytes


J Pharmacol Exp Ther 292: 1146-52 (2000)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 11


(Homo sapiens)
BDBM50420185
PNG
(CHEMBL1233636)
Show SMILES OS(=O)(=O)Oc1c[nH]c2ccccc12
Show InChI InChI=1S/C8H7NO4S/c10-14(11,12)13-8-5-9-7-4-2-1-3-6(7)8/h1-5,9H,(H,10,11,12)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
UniChem

Similars

AffyNet 
PubMed
1.81E+5n/an/an/an/an/an/an/an/a



Nagoya University School of Medicine

Curated by ChEMBL


Assay Description
TP_TRANSPORTER: uptake&inhibition of estrone sulfate in OAT4-S2 cells


Eur J Pharmacol 466: 13-20 (2003)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 11


(Homo sapiens)
BDBM50420185
PNG
(CHEMBL1233636)
Show SMILES OS(=O)(=O)Oc1c[nH]c2ccccc12
Show InChI InChI=1S/C8H7NO4S/c10-14(11,12)13-8-5-9-7-4-2-1-3-6(7)8/h1-5,9H,(H,10,11,12)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
UniChem

Similars

AffyNet 
PubMed
1.81E+5n/an/an/an/an/an/an/an/a



Nagoya University School of Medicine

Curated by ChEMBL


Assay Description
TP_TRANSPORTER: inhibition of E1S uptake (E1S: 5 uM, indoxyl sulfate:500 uM) in S2 cells expressing human-OAT4


Eur J Pharmacol 466: 13-20 (2003)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 11


(Homo sapiens)
BDBM23432
PNG
(octanoate | octanoate, 1 | octanoic acid | octanoi...)
Show SMILES CCCCCCCC([O-])=O
Show InChI InChI=1S/C8H16O2/c1-2-3-4-5-6-7-8(9)10/h2-7H2,1H3,(H,9,10)/p-1
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
PDB
UniChem

Patents


Similars

AffyNet 
PubMed
2.36E+5n/an/an/an/an/an/an/an/a



Kyorin University School of Medicine

Curated by ChEMBL


Assay Description
TP_TRANSPORTER: inhibition of Ochratoxin A uptake in OAT4-expressing S2 cells


Biochim Biophys Acta 1590: 64-75 (2002)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 11


(Homo sapiens)
BDBM50344961
PNG
(CHEMBL510139 | citrinin)
Show SMILES C[C@H]1OC=C2C(=O)C(C(O)=O)C(=O)C(C)=C2[C@@H]1C
Show InChI InChI=1S/C13H14O5/c1-5-7(3)18-4-8-9(5)6(2)11(14)10(12(8)15)13(16)17/h4-5,7,10H,1-3H3,(H,16,17)/t5-,7-,10?/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem
AffyNet 
PubMed
3.66E+5n/an/an/an/an/an/an/an/a



Kyorin University School of Medicine

Curated by ChEMBL


Assay Description
TP_TRANSPORTER: inhibition of Ochratoxin A uptake in OAT4-expressing S2 cells


Biochim Biophys Acta 1590: 64-75 (2002)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 11


(Homo sapiens)
BDBM50344964
PNG
(Betamipron | CHEMBL1231530 | N-(phenylcarbonyl)-be...)
Show SMILES OC(=O)CCNC(=O)c1ccccc1
Show InChI InChI=1S/C10H11NO3/c12-9(13)6-7-11-10(14)8-4-2-1-3-5-8/h1-5H,6-7H2,(H,11,14)(H,12,13)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
MMDB
PC cid
PC sid
PDB
UniChem

Patents


Similars

AffyNet 
PubMed
5.02E+5n/an/an/an/an/an/an/an/a



Nagoya University School of Medicine

Curated by ChEMBL


Assay Description
TP_TRANSPORTER: inhibition of E1S uptake in OAT4-expressing S2 cells


J Pharmacol Exp Ther 301: 797-802 (2002)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 1


(Homo sapiens)
BDBM50079455
PNG
(CHEMBL46486 | TETRAMETHYLAMMONIUM | tetramethylamm...)
Show SMILES C[N+](C)(C)C
Show InChI InChI=1S/C4H12N/c1-5(2,3)4/h1-4H3/q+1
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
UniChem

Patents


Similars

AffyNet 
PubMed
1.24E+7n/an/an/an/an/an/an/an/a



University of California

Curated by ChEMBL


Assay Description
TP_TRANSPORTER: inhibition of MPP+ uptake in Xenopus laevis oocytes


J Pharmacol Exp Ther 292: 1146-52 (2000)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 1


(Homo sapiens)
BDBM85213
PNG
(Agmatine | CAS_306-60-5 | CHEMBL58343 | NSC_199 | ...)
Show SMILES NCCCCN=C(N)N
Show InChI InChI=1S/C5H14N4/c6-3-1-2-4-9-5(7)8/h1-4,6H2,(H4,7,8,9)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
MMDB
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
Article
PubMed
2.40E+7n/an/an/an/an/an/an/an/a



University of Cologne

Curated by ChEMBL


Assay Description
TP_TRANSPORTER: inhibition of uptake of 0.1 uM MPP+ in OCT1-expressing 293 cells


Citation and Details
More data for this
Ligand-Target Pair
Uric Acid Transporter 1 (URAT1)


(Homo sapiens (Human))
BDBM165874
PNG
(US9067922, 213 | US9067922, 225)
Show SMILES Fc1ccc(Oc2cc(F)c(cc2Cl)S(=O)(=O)Nc2ncccn2)cc1C#N
Show InChI InChI=1S/C17H9ClF2N4O3S/c18-12-7-16(28(25,26)24-17-22-4-1-5-23-17)14(20)8-15(12)27-11-2-3-13(19)10(6-11)9-21/h1-8H,(H,22,23,24)
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
US Patent
n/an/a 0n/an/an/an/an/an/a



Pfizer Limited

US Patent


Assay Description
Assay compound plates were prepared by diluting the compounds of formula (I) with chloride-free buffer (125 mM Na-gluconate, 4.8 mM K-gluconate, 1.3 ...


US Patent US9067922 (2015)

More data for this
Ligand-Target Pair
Uric Acid Transporter 1 (URAT1)


(Homo sapiens (Human))
BDBM165905
PNG
(US9067922, 247)
Show SMILES OCc1ccc(Oc2ccc(cc2C#N)S(=O)(=O)Nc2ccc(F)cn2)cc1Cl
Show InChI InChI=1S/C19H13ClFN3O4S/c20-17-8-15(3-1-12(17)11-25)28-18-5-4-16(7-13(18)9-22)29(26,27)24-19-6-2-14(21)10-23-19/h1-8,10,25H,11H2,(H,23,24)
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
US Patent
n/an/a 1n/an/an/an/an/an/a



Pfizer Limited

US Patent


Assay Description
Assay compound plates were prepared by diluting the compounds of formula (I) with chloride-free buffer (125 mM Na-gluconate, 4.8 mM K-gluconate, 1.3 ...


US Patent US9067922 (2015)

More data for this
Ligand-Target Pair
Uric Acid Transporter 1 (URAT1)


(Homo sapiens (Human))
BDBM165898
PNG
(US9067922, 239)
Show SMILES OCc1ncc(Oc2ccc(c(F)c2)S(=O)(=O)Nc2ccc(F)cn2)cc1Cl
Show InChI InChI=1S/C17H12ClF2N3O4S/c18-13-5-12(8-21-15(13)9-24)27-11-2-3-16(14(20)6-11)28(25,26)23-17-4-1-10(19)7-22-17/h1-8,24H,9H2,(H,22,23)
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
AffyNet 
US Patent
n/an/a 2n/an/an/an/an/an/a



Pfizer Limited

US Patent


Assay Description
Assay compound plates were prepared by diluting the compounds of formula (I) with chloride-free buffer (125 mM Na-gluconate, 4.8 mM K-gluconate, 1.3 ...


US Patent US9067922 (2015)

More data for this
Ligand-Target Pair
Uric Acid Transporter 1 (URAT1)


(Homo sapiens (Human))
BDBM165900
PNG
(US9067922, 241)
Show SMILES Fc1ccc(NS(=O)(=O)c2ccc(Oc3cc(Cl)c(C#N)c(Cl)c3)c(c2)C#N)nc1
Show InChI InChI=1S/C19H9Cl2FN4O3S/c20-16-6-13(7-17(21)15(16)9-24)29-18-3-2-14(5-11(18)8-23)30(27,28)26-19-4-1-12(22)10-25-19/h1-7,10H,(H,25,26)
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
US Patent
n/an/a 3n/an/an/an/an/an/a



Pfizer Limited

US Patent


Assay Description
Assay compound plates were prepared by diluting the compounds of formula (I) with chloride-free buffer (125 mM Na-gluconate, 4.8 mM K-gluconate, 1.3 ...


US Patent US9067922 (2015)

More data for this
Ligand-Target Pair
Uric Acid Transporter 1 (URAT1)


(Homo sapiens (Human))
BDBM165745
PNG
(US9067922, 235 | US9067922, 79)
Show SMILES Cc1cc(Oc2ccc(cc2C#N)S(=O)(=O)Nc2ccc(F)cn2)cc(C)c1C#N
Show InChI InChI=1S/C21H15FN4O3S/c1-13-7-17(8-14(2)19(13)11-24)29-20-5-4-18(9-15(20)10-23)30(27,28)26-21-6-3-16(22)12-25-21/h3-9,12H,1-2H3,(H,25,26)
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
US Patent
n/an/a 7n/an/an/an/an/an/a



Pfizer Limited

US Patent


Assay Description
Assay compound plates were prepared by diluting the compounds of formula (I) with chloride-free buffer (125 mM Na-gluconate, 4.8 mM K-gluconate, 1.3 ...


US Patent US9067922 (2015)

More data for this
Ligand-Target Pair
Uric Acid Transporter 1 (URAT1)


(Homo sapiens (Human))
BDBM165896
PNG
(US9067922, 237)
Show SMILES Fc1ccc(NS(=O)(=O)c2ccc(Oc3cc(F)c(C#N)c(Cl)c3)c(c2)C#N)nc1
Show InChI InChI=1S/C19H9ClF2N4O3S/c20-16-6-13(7-17(22)15(16)9-24)29-18-3-2-14(5-11(18)8-23)30(27,28)26-19-4-1-12(21)10-25-19/h1-7,10H,(H,25,26)
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
US Patent
n/an/a 8n/an/an/an/an/an/a



Pfizer Limited

US Patent


Assay Description
Assay compound plates were prepared by diluting the compounds of formula (I) with chloride-free buffer (125 mM Na-gluconate, 4.8 mM K-gluconate, 1.3 ...


US Patent US9067922 (2015)

More data for this
Ligand-Target Pair
Uric Acid Transporter 1 (URAT1)


(Homo sapiens (Human))
BDBM152041
PNG
(US8987473, 122)
Show SMILES Cc1nn(Cc2c(Cl)cccc2Cl)c2cc(CCC(O)=O)ccc12
Show InChI InChI=1S/C18H16Cl2N2O2/c1-11-13-7-5-12(6-8-18(23)24)9-17(13)22(21-11)10-14-15(19)3-2-4-16(14)20/h2-5,7,9H,6,8,10H2,1H3,(H,23,24)
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
US Patent
n/an/a 10n/an/an/an/an/an/a



Sato Pharmaceutical Co., Ltd.

US Patent


Assay Description
It was introduced human URAT1 full-length cDNA into an expression vector pcDNA5 / FRT / V5-His TOPO (registered trademark) (Invitrogen). The result...


US Patent US8987473 (2015)

More data for this
Ligand-Target Pair
Uric Acid Transporter 1 (URAT1)


(Homo sapiens (Human))
BDBM152051
PNG
(US8987473, 137)
Show SMILES Cc1nn(Cc2c(Cl)cccc2Cl)c2cc(Cc3n[nH]c(=S)o3)ccc12
Show InChI InChI=1S/C18H14Cl2N4OS/c1-10-12-6-5-11(8-17-21-22-18(26)25-17)7-16(12)24(23-10)9-13-14(19)3-2-4-15(13)20/h2-7H,8-9H2,1H3,(H,22,26)
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
US Patent
n/an/a 10n/an/an/an/an/an/a



Sato Pharmaceutical Co., Ltd.

US Patent


Assay Description
It was introduced human URAT1 full-length cDNA into an expression vector pcDNA5 / FRT / V5-His TOPO (registered trademark) (Invitrogen). The result...


US Patent US8987473 (2015)

More data for this
Ligand-Target Pair
Uric Acid Transporter 1 (URAT1)


(Homo sapiens (Human))
BDBM165893
PNG
(US9067922, 232)
Show SMILES Clc1ccc(NS(=O)(=O)c2ccc(Oc3ccc(C#N)c(Cl)c3)c(c2)C#N)nc1
Show InChI InChI=1S/C19H10Cl2N4O3S/c20-14-2-6-19(24-11-14)25-29(26,27)16-4-5-18(13(7-16)10-23)28-15-3-1-12(9-22)17(21)8-15/h1-8,11H,(H,24,25)
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
US Patent
n/an/a 12n/an/an/an/an/an/a



Pfizer Limited

US Patent


Assay Description
Assay compound plates were prepared by diluting the compounds of formula (I) with chloride-free buffer (125 mM Na-gluconate, 4.8 mM K-gluconate, 1.3 ...


US Patent US9067922 (2015)

More data for this
Ligand-Target Pair
Uric Acid Transporter 1 (URAT1)


(Homo sapiens (Human))
BDBM165667
PNG
(US9067922, 1)
Show SMILES Fc1ccc(NS(=O)(=O)c2ccc(Oc3ccc(C#N)c(Cl)c3)c(c2)C#N)nc1
Show InChI InChI=1S/C19H10ClFN4O3S/c20-17-8-15(3-1-12(17)9-22)28-18-5-4-16(7-13(18)10-23)29(26,27)25-19-6-2-14(21)11-24-19/h1-8,11H,(H,24,25)
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
US Patent
n/an/a 13n/an/an/an/an/an/a



Pfizer Limited

US Patent


Assay Description
Assay compound plates were prepared by diluting the compounds of formula (I) with chloride-free buffer (125 mM Na-gluconate, 4.8 mM K-gluconate, 1.3 ...


US Patent US9067922 (2015)

More data for this
Ligand-Target Pair
Uric Acid Transporter 1 (URAT1)


(Homo sapiens (Human))
BDBM152048
PNG
(US8987473, 134)
Show SMILES Cc1nn(Cc2c(Cl)cccc2Cl)c2cc(Cc3nnn[nH]3)ccc12
Show InChI InChI=1S/C17H14Cl2N6/c1-10-12-6-5-11(8-17-20-23-24-21-17)7-16(12)25(22-10)9-13-14(18)3-2-4-15(13)19/h2-7H,8-9H2,1H3,(H,20,21,23,24)
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
US Patent
n/an/a 13n/an/an/an/an/an/a



Sato Pharmaceutical Co., Ltd.

US Patent


Assay Description
It was introduced human URAT1 full-length cDNA into an expression vector pcDNA5 / FRT / V5-His TOPO (registered trademark) (Invitrogen). The result...


US Patent US8987473 (2015)

More data for this
Ligand-Target Pair
Uric Acid Transporter 1 (URAT1)


(Homo sapiens (Human))
BDBM165745
PNG
(US9067922, 235 | US9067922, 79)
Show SMILES Cc1cc(Oc2ccc(cc2C#N)S(=O)(=O)Nc2ccc(F)cn2)cc(C)c1C#N
Show InChI InChI=1S/C21H15FN4O3S/c1-13-7-17(8-14(2)19(13)11-24)29-20-5-4-18(9-15(20)10-23)30(27,28)26-21-6-3-16(22)12-25-21/h3-9,12H,1-2H3,(H,25,26)
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
US Patent
n/an/a 13n/an/an/an/an/an/a



Pfizer Limited

US Patent


Assay Description
Assay compound plates were prepared by diluting the compounds of formula (I) with chloride-free buffer (125 mM Na-gluconate, 4.8 mM K-gluconate, 1.3 ...


US Patent US9067922 (2015)

More data for this
Ligand-Target Pair
Uric Acid Transporter 1 (URAT1)


(Homo sapiens (Human))
BDBM152017
PNG
(US8987473, 82)
Show SMILES Cc1cn(Cc2c(Cl)cccc2Cl)c2cc(CC(O)=O)ccc12
Show InChI InChI=1S/C18H15Cl2NO2/c1-11-9-21(10-14-15(19)3-2-4-16(14)20)17-7-12(8-18(22)23)5-6-13(11)17/h2-7,9H,8,10H2,1H3,(H,22,23)
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
US Patent
n/an/a 15n/an/an/an/an/an/a



Sato Pharmaceutical Co., Ltd.

US Patent


Assay Description
It was introduced human URAT1 full-length cDNA into an expression vector pcDNA5 / FRT / V5-His TOPO (registered trademark) (Invitrogen). The result...


US Patent US8987473 (2015)

More data for this
Ligand-Target Pair
Uric Acid Transporter 1 (URAT1)


(Homo sapiens (Human))
BDBM152079
PNG
(US8987473, 183)
Show SMILES Cc1nn(Cc2c(Cl)cccc2Cl)c2cc(ccc12)C(F)(F)C(O)=O
Show InChI InChI=1S/C17H12Cl2F2N2O2/c1-9-11-6-5-10(17(20,21)16(24)25)7-15(11)23(22-9)8-12-13(18)3-2-4-14(12)19/h2-7H,8H2,1H3,(H,24,25)
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
US Patent
n/an/a 15n/an/an/an/an/an/a



Sato Pharmaceutical Co., Ltd.

US Patent


Assay Description
It was introduced human URAT1 full-length cDNA into an expression vector pcDNA5 / FRT / V5-His TOPO (registered trademark) (Invitrogen). The result...


US Patent US8987473 (2015)

More data for this
Ligand-Target Pair
Uric Acid Transporter 1 (URAT1)


(Homo sapiens (Human))
BDBM165769
PNG
(US9067922, 104)
Show SMILES Fc1ccnc(NS(=O)(=O)c2ccc(Oc3ccc(C#N)c(Cl)c3)c(c2)C#N)c1
Show InChI InChI=1S/C19H10ClFN4O3S/c20-17-9-15(2-1-12(17)10-22)28-18-4-3-16(7-13(18)11-23)29(26,27)25-19-8-14(21)5-6-24-19/h1-9H,(H,24,25)
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
US Patent
n/an/a 15n/an/an/an/an/an/a



Pfizer Limited

US Patent


Assay Description
Assay compound plates were prepared by diluting the compounds of formula (I) with chloride-free buffer (125 mM Na-gluconate, 4.8 mM K-gluconate, 1.3 ...


US Patent US9067922 (2015)

More data for this
Ligand-Target Pair
Uric Acid Transporter 1 (URAT1)


(Homo sapiens (Human))
BDBM152047
PNG
(US8987473, 133)
Show SMILES Cc1nn(Cc2c(Cl)cccc2Cl)c2cc(CCCC(O)=O)ccc12
Show InChI InChI=1S/C19H18Cl2N2O2/c1-12-14-9-8-13(4-2-7-19(24)25)10-18(14)23(22-12)11-15-16(20)5-3-6-17(15)21/h3,5-6,8-10H,2,4,7,11H2,1H3,(H,24,25)
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
US Patent
n/an/a 16n/an/an/an/an/an/a



Sato Pharmaceutical Co., Ltd.

US Patent


Assay Description
It was introduced human URAT1 full-length cDNA into an expression vector pcDNA5 / FRT / V5-His TOPO (registered trademark) (Invitrogen). The result...


US Patent US8987473 (2015)

More data for this
Ligand-Target Pair
Uric Acid Transporter 1 (URAT1)


(Homo sapiens (Human))
BDBM152080
PNG
(US8987473, 185)
Show SMILES Cc1nn(Cc2c(Cl)cccc2C2CC2)c2cc(CCC(O)=O)ccc12
Show InChI InChI=1S/C21H21ClN2O2/c1-13-16-9-5-14(6-10-21(25)26)11-20(16)24(23-13)12-18-17(15-7-8-15)3-2-4-19(18)22/h2-5,9,11,15H,6-8,10,12H2,1H3,(H,25,26)
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
US Patent
n/an/a 17n/an/an/an/an/an/a



Sato Pharmaceutical Co., Ltd.

US Patent


Assay Description
It was introduced human URAT1 full-length cDNA into an expression vector pcDNA5 / FRT / V5-His TOPO (registered trademark) (Invitrogen). The result...


US Patent US8987473 (2015)

More data for this
Ligand-Target Pair
Uric Acid Transporter 1 (URAT1)


(Homo sapiens (Human))
BDBM152016
PNG
(US8987473, 80)
Show SMILES Cc1cccc(C)c1CN1CC(C)(C)c2ccc(CC(O)=O)cc12
Show InChI InChI=1S/C21H25NO2/c1-14-6-5-7-15(2)17(14)12-22-13-21(3,4)18-9-8-16(10-19(18)22)11-20(23)24/h5-10H,11-13H2,1-4H3,(H,23,24)
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
US Patent
n/an/a 18n/an/an/an/an/an/a



Sato Pharmaceutical Co., Ltd.

US Patent


Assay Description
It was introduced human URAT1 full-length cDNA into an expression vector pcDNA5 / FRT / V5-His TOPO (registered trademark) (Invitrogen). The result...


US Patent US8987473 (2015)

More data for this
Ligand-Target Pair
Uric Acid Transporter 1 (URAT1)


(Homo sapiens (Human))
BDBM152026
PNG
(US8987473, 97)
Show SMILES Cc1nn(Cc2c(Cl)cccc2Cl)c2cc(CC(O)=O)ccc12
Show InChI InChI=1S/C17H14Cl2N2O2/c1-10-12-6-5-11(8-17(22)23)7-16(12)21(20-10)9-13-14(18)3-2-4-15(13)19/h2-7H,8-9H2,1H3,(H,22,23)
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
US Patent
n/an/a 18n/an/an/an/an/an/a



Sato Pharmaceutical Co., Ltd.

US Patent


Assay Description
It was introduced human URAT1 full-length cDNA into an expression vector pcDNA5 / FRT / V5-His TOPO (registered trademark) (Invitrogen). The result...


US Patent US8987473 (2015)

More data for this
Ligand-Target Pair
Uric Acid Transporter 1 (URAT1)


(Homo sapiens (Human))
BDBM165744
PNG
(US9067922, 78)
Show SMILES Fc1ccc(NS(=O)(=O)c2ccc(Oc3ccc(F)c(Cl)c3)c(c2)C#N)nc1
Show InChI InChI=1S/C18H10ClF2N3O3S/c19-15-8-13(2-4-16(15)21)27-17-5-3-14(7-11(17)9-22)28(25,26)24-18-6-1-12(20)10-23-18/h1-8,10H,(H,23,24)
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
US Patent
n/an/a 19n/an/an/an/an/an/a



Pfizer Limited

US Patent


Assay Description
Assay compound plates were prepared by diluting the compounds of formula (I) with chloride-free buffer (125 mM Na-gluconate, 4.8 mM K-gluconate, 1.3 ...


US Patent US9067922 (2015)

More data for this
Ligand-Target Pair
Uric Acid Transporter 1 (URAT1)


(Homo sapiens (Human))
BDBM60431
PNG
(US9067922, 249)
Show SMILES Cc1cc(Oc2ccc(c(F)c2)S(=O)(=O)Nc2ccc(F)cn2)cc(C)c1C#N
Show InChI InChI=1S/C20H15F2N3O3S/c1-12-7-16(8-13(2)17(12)10-23)28-15-4-5-19(18(22)9-15)29(26,27)25-20-6-3-14(21)11-24-20/h3-9,11H,1-2H3,(H,24,25)
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
US Patent
n/an/a 21n/an/an/an/an/an/a



Pfizer Limited

US Patent


Assay Description
Assay compound plates were prepared by diluting the compounds of formula (I) with chloride-free buffer (125 mM Na-gluconate, 4.8 mM K-gluconate, 1.3 ...


US Patent US9067922 (2015)

More data for this
Ligand-Target Pair
Uric Acid Transporter 1 (URAT1)


(Homo sapiens (Human))
BDBM152011
PNG
(US8987473, 64)
Show SMILES Cc1cn(Cc2c(C)cccc2C)c2cc(CC(O)=O)ccc12
Show InChI InChI=1S/C20H21NO2/c1-13-5-4-6-14(2)18(13)12-21-11-15(3)17-8-7-16(9-19(17)21)10-20(22)23/h4-9,11H,10,12H2,1-3H3,(H,22,23)
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
US Patent
n/an/a 22n/an/an/an/an/an/a



Sato Pharmaceutical Co., Ltd.

US Patent


Assay Description
It was introduced human URAT1 full-length cDNA into an expression vector pcDNA5 / FRT / V5-His TOPO (registered trademark) (Invitrogen). The result...


US Patent US8987473 (2015)

More data for this
Ligand-Target Pair
Uric Acid Transporter 1 (URAT1)


(Homo sapiens (Human))
BDBM152049
PNG
(US8987473, 135)
Show SMILES Cc1nn(Cc2c(Cl)cccc2Cl)c2cc(CCc3nnn[nH]3)ccc12
Show InChI InChI=1S/C18H16Cl2N6/c1-11-13-7-5-12(6-8-18-21-24-25-22-18)9-17(13)26(23-11)10-14-15(19)3-2-4-16(14)20/h2-5,7,9H,6,8,10H2,1H3,(H,21,22,24,25)
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
US Patent
n/an/a 23n/an/an/an/an/an/a



Sato Pharmaceutical Co., Ltd.

US Patent


Assay Description
It was introduced human URAT1 full-length cDNA into an expression vector pcDNA5 / FRT / V5-His TOPO (registered trademark) (Invitrogen). The result...


US Patent US8987473 (2015)

More data for this
Ligand-Target Pair
Uric Acid Transporter 1 (URAT1)


(Homo sapiens (Human))
BDBM152023
PNG
(US8987473, 89)
Show SMILES Cc1cn(Cc2c(Cl)cccc2Cl)c2cc(CCC(O)=O)ccc12
Show InChI InChI=1S/C19H17Cl2NO2/c1-12-10-22(11-15-16(20)3-2-4-17(15)21)18-9-13(5-7-14(12)18)6-8-19(23)24/h2-5,7,9-10H,6,8,11H2,1H3,(H,23,24)
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
US Patent
n/an/a 23n/an/an/an/an/an/a



Sato Pharmaceutical Co., Ltd.

US Patent


Assay Description
It was introduced human URAT1 full-length cDNA into an expression vector pcDNA5 / FRT / V5-His TOPO (registered trademark) (Invitrogen). The result...


US Patent US8987473 (2015)

More data for this
Ligand-Target Pair
Uric Acid Transporter 1 (URAT1)


(Homo sapiens (Human))
BDBM152054
PNG
(US8987473, 140)
Show SMILES CCc1nn(Cc2c(Cl)cccc2Cl)c2cc(CC(O)=O)ccc12
Show InChI InChI=1S/C18H16Cl2N2O2/c1-2-16-12-7-6-11(9-18(23)24)8-17(12)22(21-16)10-13-14(19)4-3-5-15(13)20/h3-8H,2,9-10H2,1H3,(H,23,24)
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
US Patent
n/an/a 24n/an/an/an/an/an/a



Sato Pharmaceutical Co., Ltd.

US Patent


Assay Description
It was introduced human URAT1 full-length cDNA into an expression vector pcDNA5 / FRT / V5-His TOPO (registered trademark) (Invitrogen). The result...


US Patent US8987473 (2015)

More data for this
Ligand-Target Pair
Uric Acid Transporter 1 (URAT1)


(Homo sapiens (Human))
BDBM165780
PNG
(US9067922, 115)
Show SMILES COc1cccc(C)c1Oc1ccc(cc1C#N)S(=O)(=O)Nc1ccc(F)cn1
Show InChI InChI=1S/C20H16FN3O4S/c1-13-4-3-5-18(27-2)20(13)28-17-8-7-16(10-14(17)11-22)29(25,26)24-19-9-6-15(21)12-23-19/h3-10,12H,1-2H3,(H,23,24)
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
US Patent
n/an/a 24n/an/an/an/an/an/a



Pfizer Limited

US Patent


Assay Description
Assay compound plates were prepared by diluting the compounds of formula (I) with chloride-free buffer (125 mM Na-gluconate, 4.8 mM K-gluconate, 1.3 ...


US Patent US9067922 (2015)

More data for this
Ligand-Target Pair
Displayed 1 to 50 (of 455 total )  |  Next  |  Last  >>
Jump to: