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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Son of sevenless homolog 1' AND taxid = 9606   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Son of sevenless homolog 1


(Homo sapiens)
BDBM50421182
PNG
(CHEMBL2086797)
Show SMILES CC[C@H](C)[C@H](NC(=O)CN1C\C=C/CCC(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](CCC(O)=O)C1=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(N)=O)C(N)=O
Show InChI InChI=1S/C92H142N22O27/c1-11-51(8)76(113-71(118)47-114-40-19-13-16-25-70(117)101-67(44-54-21-14-12-15-22-54)88(138)107-62(91(114)141)33-37-75(125)126)90(140)112-68(45-55-26-28-56(115)29-27-55)89(139)104-58(24-20-39-98-92(96)97)82(132)109-64(41-48(2)3)86(136)106-61(32-36-74(123)124)84(134)110-66(43-50(6)7)87(137)111-65(42-49(4)5)85(135)103-57(23-17-18-38-93)80(130)99-52(9)78(128)102-60(31-35-73(121)122)83(133)105-59(30-34-72(119)120)81(131)100-53(10)79(129)108-63(77(95)127)46-69(94)116/h12-15,19,21-22,26-29,48-53,57-68,76,115H,11,16-18,20,23-25,30-47,93H2,1-10H3,(H2,94,116)(H2,95,127)(H,99,130)(H,100,131)(H,101,117)(H,102,128)(H,103,135)(H,104,139)(H,105,133)(H,106,136)(H,107,138)(H,108,129)(H,109,132)(H,110,134)(H,111,137)(H,112,140)(H,113,118)(H,119,120)(H,121,122)(H,123,124)(H,125,126)(H4,96,97,98)/b19-13-/t51-,52-,53-,57-,58-,59-,60-,61-,62-,63-,64-,65-,66-,67-,68-,76-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 2.50E+4n/an/an/an/an/an/a



Genentech

Curated by ChEMBL


Assay Description
Inhibition to His6-tagged Sos1 catalytic domain-mediated nucleotide exchange by fluorimetric assay


Citation and Details
More data for this
Ligand-Target Pair