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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sphingosine-1-phosphate lyase 1' AND taxid = 10090   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sphingosine-1-phosphate lyase 1


(Mus musculus)
BDBM50268100
PNG
(CHEMBL491458 | N-(4-(1H-imidazol-1-yl)benzyl)-4-am...)
Show SMILES Nc1nc(nc2n(CC3CCCO3)cc(C(=O)NCc3ccc(cc3)-n3ccnc3)c(=O)c12)N1CCCCC1
Show InChI InChI=1S/C28H32N8O3/c29-25-23-24(37)22(27(38)31-15-19-6-8-20(9-7-19)35-13-10-30-18-35)17-36(16-21-5-4-14-39-21)26(23)33-28(32-25)34-11-2-1-3-12-34/h6-10,13,17-18,21H,1-5,11-12,14-16H2,(H,31,38)(H2,29,32,33)
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PC cid
PC sid
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AffyNet 
Article
PubMed
n/an/a 2.10E+3n/an/an/an/an/an/a



Princ

Curated by ChEMBL


Assay Description
Inhibition of sphingosine-1-phosphate lyase in mouse spleen by scintillation counting


Citation and Details
More data for this
Ligand-Target Pair