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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Src homology 2 domain mutant (SH2-tm)' AND taxid = 269447   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Src homology 2 domain mutant (SH2-tm)


(Rous sarcoma virus (Virus))
BDBM195583
PNG
(Phosphotyrosine (pTyr))
Show SMILES [NH3+][C@@H](Cc1ccc(OP([O-])([O-])=O)cc1)C([O-])=O
Show InChI InChI=1/C9H12NO6P/c10-8(9(11)12)5-6-1-3-7(4-2-6)16-17(13,14)15/h1-4,8H,5,10H2,(H,11,12)(H2,13,14,15)/p-2/t8-/s2
PDB

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
AffyNet 
Article
PubMed
n/an/an/a 4.90n/an/an/an/an/a



University of Nebraska-Lincoln



Assay Description
Three fluorescein-labeled peptide probes, FITC-sulfopeptide, FITC-phosphopeptide, and FITC-tyrosinepeptide (FITC, fluorescein isothiocyanate), were u...


Citation and Details
More data for this
Ligand-Target Pair
Src homology 2 domain mutant (SH2-tm)


(Rous sarcoma virus (Virus))
BDBM195582
PNG
(Sulfotyrosine (sTyr))
Show SMILES [NH3+][C@@H](Cc1ccc(OS([O-])(=O)=O)cc1)C([O-])=O
Show InChI InChI=1/C9H11NO6S/c10-8(9(11)12)5-6-1-3-7(4-2-6)16-17(13,14)15/h1-4,8H,5,10H2,(H,11,12)(H,13,14,15)/p-1/t8-/s2
PDB

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
AffyNet 
Article
PubMed
n/an/an/a 349n/an/an/an/an/a



University of Nebraska-Lincoln



Assay Description
Three fluorescein-labeled peptide probes, FITC-sulfopeptide, FITC-phosphopeptide, and FITC-tyrosinepeptide (FITC, fluorescein isothiocyanate), were u...


Citation and Details
More data for this
Ligand-Target Pair