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Compile Data Set for Download or QSAR

Found 13 hits Enz. Inhib. hit(s) with Target = 'Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial' AND taxid = 1047171   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial


(Septoria tritici)
BDBM50191588
PNG
((2R,3S,6S,7R,8R)-3-[(3-formamido-2-hydroxybenzoyl)...)
Show SMILES CCCCCC[C@@H]1[C@@H](OC(=O)CC(C)C)[C@H](C)OC(=O)[C@@H](NC(=O)c2cccc(NC=O)c2O)[C@@H](C)OC1=O
Show InChI InChI=1S/C28H40N2O9/c1-6-7-8-9-11-20-25(39-22(32)14-16(2)3)18(5)38-28(36)23(17(4)37-27(20)35)30-26(34)19-12-10-13-21(24(19)33)29-15-31/h10,12-13,15-18,20,23,25,33H,6-9,11,14H2,1-5H3,(H,29,31)(H,30,34)/t17-,18+,20-,23+,25+/m1/s1
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n/an/a 2n/an/an/an/an/an/a



Stine/Haskell Research Center

Curated by ChEMBL


Assay Description
Inhibition of Septoria nodorum succinate dehydrogenase and Qi site of mitochondrial respiratory chain complex 3 by FMET2-3 assay


Citation and Details
More data for this
Ligand-Target Pair
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial


(Septoria tritici)
BDBM50411095
PNG
(CHEMBL439507)
Show SMILES Oc1c(ccc2nn[nH]c12)C(=O)Nc1ccc(Oc2ccc(cc2)C(F)(F)F)cc1
Show InChI InChI=1S/C20H13F3N4O3/c21-20(22,23)11-1-5-13(6-2-11)30-14-7-3-12(4-8-14)24-19(29)15-9-10-16-17(18(15)28)26-27-25-16/h1-10,28H,(H,24,29)(H,25,26,27)
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n/an/a 5n/an/an/an/an/an/a



Stine/Haskell Research Center

Curated by ChEMBL


Assay Description
Inhibition of Septoria nodorum succinate dehydrogenase and Qi site of mitochondrial respiratory chain complex 3 by FMET2-3 assay


Citation and Details
More data for this
Ligand-Target Pair
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial


(Septoria tritici)
BDBM50411096
PNG
(CHEMBL378123)
Show SMILES Oc1c(sc2c[nH]nc12)C(=O)Nc1ccc(Oc2ccc(cc2)C(F)(F)F)cc1
Show InChI InChI=1S/C19H12F3N3O3S/c20-19(21,22)10-1-5-12(6-2-10)28-13-7-3-11(4-8-13)24-18(27)17-16(26)15-14(29-17)9-23-25-15/h1-9,26H,(H,23,25)(H,24,27)
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n/an/a 26n/an/an/an/an/an/a



Stine/Haskell Research Center

Curated by ChEMBL


Assay Description
Inhibition of Septoria nodorum succinate dehydrogenase and Qi site of mitochondrial respiratory chain complex 3 by FMET2-3 assay


Citation and Details
More data for this
Ligand-Target Pair
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial


(Septoria tritici)
BDBM50411094
PNG
(CHEMBL379116)
Show SMILES Cc1ccc(Oc2ccc(NC(=O)c3ccc4c[nH]nc4c3O)cc2)cc1
Show InChI InChI=1S/C21H17N3O3/c1-13-2-7-16(8-3-13)27-17-9-5-15(6-10-17)23-21(26)18-11-4-14-12-22-24-19(14)20(18)25/h2-12,25H,1H3,(H,22,24)(H,23,26)
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n/an/a 26n/an/an/an/an/an/a



Stine/Haskell Research Center

Curated by ChEMBL


Assay Description
Inhibition of Septoria nodorum succinate dehydrogenase and Qi site of mitochondrial respiratory chain complex 3 by FMET2-3 assay


Citation and Details
More data for this
Ligand-Target Pair
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial


(Septoria tritici)
BDBM50411097
PNG
(CHEMBL379557)
Show SMILES Oc1c(ccc2nn[nH]c12)C(=O)Nc1ccc(Oc2ccccc2)cc1
Show InChI InChI=1S/C19H14N4O3/c24-18-15(10-11-16-17(18)22-23-21-16)19(25)20-12-6-8-14(9-7-12)26-13-4-2-1-3-5-13/h1-11,24H,(H,20,25)(H,21,22,23)
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n/an/a 32n/an/an/an/an/an/a



Stine/Haskell Research Center

Curated by ChEMBL


Assay Description
Inhibition of Septoria nodorum succinate dehydrogenase and Qi site of mitochondrial respiratory chain complex 3 by FMET2-3 assay


Citation and Details
More data for this
Ligand-Target Pair
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial


(Septoria tritici)
BDBM50411098
PNG
(CHEMBL377384)
Show SMILES Oc1c(ccc2c[nH]nc12)C(=O)Nc1ccc(Oc2ccccc2)cc1
Show InChI InChI=1S/C20H15N3O3/c24-19-17(11-6-13-12-21-23-18(13)19)20(25)22-14-7-9-16(10-8-14)26-15-4-2-1-3-5-15/h1-12,24H,(H,21,23)(H,22,25)
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n/an/a 127n/an/an/an/an/an/a



Stine/Haskell Research Center

Curated by ChEMBL


Assay Description
Inhibition of Septoria nodorum succinate dehydrogenase and Qi site of mitochondrial respiratory chain complex 3 by FMET2-3 assay


Citation and Details
More data for this
Ligand-Target Pair
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial


(Septoria tritici)
BDBM50411095
PNG
(CHEMBL439507)
Show SMILES Oc1c(ccc2nn[nH]c12)C(=O)Nc1ccc(Oc2ccc(cc2)C(F)(F)F)cc1
Show InChI InChI=1S/C20H13F3N4O3/c21-20(22,23)11-1-5-13(6-2-11)30-14-7-3-12(4-8-14)24-19(29)15-9-10-16-17(18(15)28)26-27-25-16/h1-10,28H,(H,24,29)(H,25,26,27)
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n/an/a 1.82E+3n/an/an/an/an/an/a



Stine/Haskell Research Center

Curated by ChEMBL


Assay Description
Inhibition of Septoria nodorum succinate dehydrogenase by FMET2 assay


Citation and Details
More data for this
Ligand-Target Pair
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial


(Septoria tritici)
BDBM50411098
PNG
(CHEMBL377384)
Show SMILES Oc1c(ccc2c[nH]nc12)C(=O)Nc1ccc(Oc2ccccc2)cc1
Show InChI InChI=1S/C20H15N3O3/c24-19-17(11-6-13-12-21-23-18(13)19)20(25)22-14-7-9-16(10-8-14)26-15-4-2-1-3-5-15/h1-12,24H,(H,21,23)(H,22,25)
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n/an/a>3.00E+4n/an/an/an/an/an/a



Stine/Haskell Research Center

Curated by ChEMBL


Assay Description
Inhibition of Septoria nodorum succinate dehydrogenase by FMET2 assay


Citation and Details
More data for this
Ligand-Target Pair
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial


(Septoria tritici)
BDBM50191588
PNG
((2R,3S,6S,7R,8R)-3-[(3-formamido-2-hydroxybenzoyl)...)
Show SMILES CCCCCC[C@@H]1[C@@H](OC(=O)CC(C)C)[C@H](C)OC(=O)[C@@H](NC(=O)c2cccc(NC=O)c2O)[C@@H](C)OC1=O
Show InChI InChI=1S/C28H40N2O9/c1-6-7-8-9-11-20-25(39-22(32)14-16(2)3)18(5)38-28(36)23(17(4)37-27(20)35)30-26(34)19-12-10-13-21(24(19)33)29-15-31/h10,12-13,15-18,20,23,25,33H,6-9,11,14H2,1-5H3,(H,29,31)(H,30,34)/t17-,18+,20-,23+,25+/m1/s1
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n/an/a>3.00E+4n/an/an/an/an/an/a



Stine/Haskell Research Center

Curated by ChEMBL


Assay Description
Inhibition of Septoria nodorum succinate dehydrogenase by FMET2 assay


Citation and Details
More data for this
Ligand-Target Pair
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial


(Septoria tritici)
BDBM50411096
PNG
(CHEMBL378123)
Show SMILES Oc1c(sc2c[nH]nc12)C(=O)Nc1ccc(Oc2ccc(cc2)C(F)(F)F)cc1
Show InChI InChI=1S/C19H12F3N3O3S/c20-19(21,22)10-1-5-12(6-2-10)28-13-7-3-11(4-8-13)24-18(27)17-16(26)15-14(29-17)9-23-25-15/h1-9,26H,(H,23,25)(H,24,27)
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n/an/a>3.00E+4n/an/an/an/an/an/a



Stine/Haskell Research Center

Curated by ChEMBL


Assay Description
Inhibition of Septoria nodorum succinate dehydrogenase by FMET2 assay


Citation and Details
More data for this
Ligand-Target Pair
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial


(Septoria tritici)
BDBM50411099
PNG
(CHEMBL211246)
Show SMILES Oc1c(ccc2nc[nH]c12)C(=O)Nc1ccc(Oc2ccccc2)cc1
Show InChI InChI=1S/C20H15N3O3/c24-19-16(10-11-17-18(19)22-12-21-17)20(25)23-13-6-8-15(9-7-13)26-14-4-2-1-3-5-14/h1-12,24H,(H,21,22)(H,23,25)
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n/an/a>3.00E+4n/an/an/an/an/an/a



Stine/Haskell Research Center

Curated by ChEMBL


Assay Description
Inhibition of Septoria nodorum succinate dehydrogenase and Qi site of mitochondrial respiratory chain complex 3 by FMET2-3 assay


Citation and Details
More data for this
Ligand-Target Pair
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial


(Septoria tritici)
BDBM50411099
PNG
(CHEMBL211246)
Show SMILES Oc1c(ccc2nc[nH]c12)C(=O)Nc1ccc(Oc2ccccc2)cc1
Show InChI InChI=1S/C20H15N3O3/c24-19-16(10-11-17-18(19)22-12-21-17)20(25)23-13-6-8-15(9-7-13)26-14-4-2-1-3-5-14/h1-12,24H,(H,21,22)(H,23,25)
UniProtKB/SwissProt

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n/an/a>3.00E+4n/an/an/an/an/an/a



Stine/Haskell Research Center

Curated by ChEMBL


Assay Description
Inhibition of Septoria nodorum succinate dehydrogenase by FMET2 assay


Citation and Details
More data for this
Ligand-Target Pair
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial


(Septoria tritici)
BDBM50411097
PNG
(CHEMBL379557)
Show SMILES Oc1c(ccc2nn[nH]c12)C(=O)Nc1ccc(Oc2ccccc2)cc1
Show InChI InChI=1S/C19H14N4O3/c24-18-15(10-11-16-17(18)22-23-21-16)19(25)20-12-6-8-14(9-7-12)26-13-4-2-1-3-5-13/h1-11,24H,(H,20,25)(H,21,22,23)
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n/an/a>3.00E+4n/an/an/an/an/an/a



Stine/Haskell Research Center

Curated by ChEMBL


Assay Description
Inhibition of Septoria nodorum succinate dehydrogenase by FMET2 assay


Citation and Details
More data for this
Ligand-Target Pair