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Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'TNF receptor-associated factor 6' AND taxid = 9606   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
TNF receptor-associated factor 6


(Homo sapiens)
BDBM50095636
PNG
(CHEMBL3590511)
Show SMILES OC(=O)c1ccc(NC(=O)Cn2c3ccccc3sc2=O)cc1
Show InChI InChI=1S/C16H12N2O4S/c19-14(17-11-7-5-10(6-8-11)15(20)21)9-18-12-3-1-2-4-13(12)23-16(18)22/h1-8H,9H2,(H,17,19)(H,20,21)
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem

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Article
PubMed
n/an/an/a 1.90E+6n/an/an/an/an/a



Eisai Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of human TRAF6 interaction with biotinylated RANK peptide by NMR interaction analysis


Citation and Details
More data for this
Ligand-Target Pair
TNF receptor-associated factor 6


(Homo sapiens)
BDBM50095835
PNG
(CHEMBL3590514)
Show SMILES COc1ccc(cc1Cl)S(=O)(=O)NC(=O)c1ccc(NC(=O)Cn2c3cc(Cl)ccc3sc2=O)cc1
Show InChI InChI=1S/C19H22N6O6/c1-29-10-4-3-9(5-11(10)30-2)6-21-18(28)15-13(26)14(27)19(31-15)25-8-24-12-16(20)22-7-23-17(12)25/h3-5,7-8,13-15,19,26-27H,6H2,1-2H3,(H,21,28)(H2,20,22,23)/t13?,14?,15-,19+/m0/s1
PDB

UniProtKB/SwissProt

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UniChem

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Article
PubMed
n/an/an/a 3.50E+4n/an/an/an/an/a



Eisai Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of human TRAF6 interaction with biotinylated RANK peptide by NMR interaction analysis


Citation and Details
More data for this
Ligand-Target Pair
TNF receptor-associated factor 6


(Homo sapiens)
BDBM50095638
PNG
(CHEMBL3590513)
Show SMILES CS(=O)(=O)NC(=O)c1ccc(NC(=O)Cn2c3cc(Cl)ccc3sc2=O)cc1
Show InChI InChI=1S/C17H14ClN3O5S2/c1-28(25,26)20-16(23)10-2-5-12(6-3-10)19-15(22)9-21-13-8-11(18)4-7-14(13)27-17(21)24/h2-8H,9H2,1H3,(H,19,22)(H,20,23)
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem

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Article
PubMed
n/an/an/a 9.90E+5n/an/an/an/an/a



Eisai Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of human TRAF6 interaction with biotinylated RANK peptide by NMR interaction analysis


Citation and Details
More data for this
Ligand-Target Pair
TNF receptor-associated factor 6


(Homo sapiens)
BDBM50095637
PNG
(CHEMBL3590512)
Show SMILES OC(=O)c1ccc(NC(=O)Cn2c3cc(Cl)ccc3sc2=O)cc1
Show InChI InChI=1S/C16H11ClN2O4S/c17-10-3-6-13-12(7-10)19(16(23)24-13)8-14(20)18-11-4-1-9(2-5-11)15(21)22/h1-7H,8H2,(H,18,20)(H,21,22)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/a 1.70E+6n/an/an/an/an/a



Eisai Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of human TRAF6 interaction with biotinylated RANK peptide by NMR interaction analysis


Citation and Details
More data for this
Ligand-Target Pair