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Found 1 hit Enz. Inhib. hit(s) with Target = 'Tandem CD1-CD2 construct H255V (hCD12 H255V)' AND taxid = Q9UBN7   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tandem CD1-CD2 construct H255V (hCD12 H255V)


(Homo sapiens)
BDBM198125
PNG
(fl-SAHA)
Show SMILES ONC(=O)CCCCCCC(=O)Nc1ccc(c(c1)C(O)=O)-c1c2ccc(O)cc2oc2cc(=O)ccc12
Show InChI InChI=1S/C28H26N2O8/c31-17-8-11-20-23(14-17)38-24-15-18(32)9-12-21(24)27(20)19-10-7-16(13-22(19)28(35)36)29-25(33)5-3-1-2-4-6-26(34)30-37/h7-15,31,37H,1-6H2,(H,29,33)(H,30,34)(H,35,36)
PDB

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
AffyNet 
n/an/an/a 240n/an/an/an/an/a



University of Pennsylvania,



Assay Description
The fluorescence anisotropy assay was performed with fluorescein-labeled SAHA (fl-SAHA, gift of C. Fierke, University of Michigan) and measured using...


Nat Chem Biol 12: 741-747 (2016)

More data for this
Ligand-Target Pair