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Found 151 hits Enz. Inhib. hit(s) with Target = 'Taste receptor type 2 member 14' AND taxid = 9606   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Taste receptor type 2 member 14


(Homo sapiens (Human))
BDBM211090
PNG
(US9247759, 5-11)
Show SMILES Cc1ccc(cc1)S(=O)(=O)N(CC1CCC(CC1)C(O)=O)Cc1ccccc1
Show InChI InChI=1S/C22H27NO4S/c1-17-7-13-21(14-8-17)28(26,27)23(15-18-5-3-2-4-6-18)16-19-9-11-20(12-10-19)22(24)25/h2-8,13-14,19-20H,9-12,15-16H2,1H3,(H,24,25)
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n/an/a 14n/an/an/an/an/an/a



Senomyx, Inc.

US Patent


Assay Description
In another embodiment, Fluorescence Polarization ("FP") based assays may be used to detect and monitor ligand binding. Fluorescence polarization is a...


US Patent US9247759 (2016)

More data for this
Ligand-Target Pair
Taste receptor type 2 member 14


(Homo sapiens (Human))
BDBM211181
PNG
(US9247759, 5-128)
Show SMILES COc1cccc(CN(CC2CCC(CC2)C(O)=O)S(=O)(=O)c2ccc(C)cc2)c1
Show InChI InChI=1S/C23H29NO5S/c1-17-6-12-22(13-7-17)30(27,28)24(16-19-4-3-5-21(14-19)29-2)15-18-8-10-20(11-9-18)23(25)26/h3-7,12-14,18,20H,8-11,15-16H2,1-2H3,(H,25,26)
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n/an/a 36n/an/an/an/an/an/a



Senomyx, Inc.

US Patent


Assay Description
In another embodiment, Fluorescence Polarization ("FP") based assays may be used to detect and monitor ligand binding. Fluorescence polarization is a...


US Patent US9247759 (2016)

More data for this
Ligand-Target Pair
Taste receptor type 2 member 14


(Homo sapiens (Human))
BDBM211114
PNG
(US9247759, 5-37)
Show SMILES Cc1ccc(cc1)S(=O)(=O)N(Cc1ccc(F)cc1)Cc1ccc(cc1)C(O)=O
Show InChI InChI=1S/C22H20FNO4S/c1-16-2-12-21(13-3-16)29(27,28)24(15-18-6-10-20(23)11-7-18)14-17-4-8-19(9-5-17)22(25)26/h2-13H,14-15H2,1H3,(H,25,26)
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n/an/a 54n/an/an/an/an/an/a



Senomyx, Inc.

US Patent


Assay Description
In another embodiment, Fluorescence Polarization ("FP") based assays may be used to detect and monitor ligand binding. Fluorescence polarization is a...


US Patent US9247759 (2016)

More data for this
Ligand-Target Pair
Taste receptor type 2 member 14


(Homo sapiens (Human))
BDBM211099
PNG
(US9247759, 5-20)
Show SMILES Cc1ccc(cc1)S(=O)(=O)N(CC1CCC(CC1)C(O)=O)Cc1ccc(F)cc1
Show InChI InChI=1S/C22H26FNO4S/c1-16-2-12-21(13-3-16)29(27,28)24(15-18-6-10-20(23)11-7-18)14-17-4-8-19(9-5-17)22(25)26/h2-3,6-7,10-13,17,19H,4-5,8-9,14-15H2,1H3,(H,25,26)
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n/an/a 83n/an/an/an/an/an/a



Senomyx, Inc.

US Patent


Assay Description
In another embodiment, Fluorescence Polarization ("FP") based assays may be used to detect and monitor ligand binding. Fluorescence polarization is a...


US Patent US9247759 (2016)

More data for this
Ligand-Target Pair
Taste receptor type 2 member 14


(Homo sapiens (Human))
BDBM211176
PNG
(US9247759, 5-123)
Show SMILES COc1ccc(cc1)S(=O)(=O)N(CC1CCC(CC1)C(O)=O)Cc1ccc(F)cc1
Show InChI InChI=1S/C22H26FNO5S/c1-29-20-10-12-21(13-11-20)30(27,28)24(15-17-4-8-19(23)9-5-17)14-16-2-6-18(7-3-16)22(25)26/h4-5,8-13,16,18H,2-3,6-7,14-15H2,1H3,(H,25,26)
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n/an/a 92n/an/an/an/an/an/a



Senomyx, Inc.

US Patent


Assay Description
In another embodiment, Fluorescence Polarization ("FP") based assays may be used to detect and monitor ligand binding. Fluorescence polarization is a...


US Patent US9247759 (2016)

More data for this
Ligand-Target Pair
Taste receptor type 2 member 14


(Homo sapiens (Human))
BDBM211179
PNG
(US9247759, 5-126)
Show SMILES Cc1ccc(CN(CC2CCC(CC2)C(O)=O)S(=O)(=O)c2ccc(C)cc2)cc1
Show InChI InChI=1S/C23H29NO4S/c1-17-3-7-19(8-4-17)15-24(16-20-9-11-21(12-10-20)23(25)26)29(27,28)22-13-5-18(2)6-14-22/h3-8,13-14,20-21H,9-12,15-16H2,1-2H3,(H,25,26)
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n/an/a 109n/an/an/an/an/an/a



Senomyx, Inc.

US Patent


Assay Description
In another embodiment, Fluorescence Polarization ("FP") based assays may be used to detect and monitor ligand binding. Fluorescence polarization is a...


US Patent US9247759 (2016)

More data for this
Ligand-Target Pair
Taste receptor type 2 member 14


(Homo sapiens (Human))
BDBM211119
PNG
(US9247759, 5-43)
Show SMILES COc1cccc(CN(Cc2ccc(cc2)C(O)=O)S(=O)(=O)c2ccc(O)cc2)c1
Show InChI InChI=1S/C22H21NO6S/c1-29-20-4-2-3-17(13-20)15-23(14-16-5-7-18(8-6-16)22(25)26)30(27,28)21-11-9-19(24)10-12-21/h2-13,24H,14-15H2,1H3,(H,25,26)
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n/an/a 188n/an/an/an/an/an/a



Senomyx, Inc.

US Patent


Assay Description
In another embodiment, Fluorescence Polarization ("FP") based assays may be used to detect and monitor ligand binding. Fluorescence polarization is a...


US Patent US9247759 (2016)

More data for this
Ligand-Target Pair
Taste receptor type 2 member 14


(Homo sapiens (Human))
BDBM60947
PNG
(BDBM50443972 | US9247759, compound C)
Show SMILES COc1ccc(CN(Cc2ccccc2)S(=O)(=O)c2ccc(cc2)C(O)=O)cc1
Show InChI InChI=1S/C22H21NO5S/c1-28-20-11-7-18(8-12-20)16-23(15-17-5-3-2-4-6-17)29(26,27)21-13-9-19(10-14-21)22(24)25/h2-14H,15-16H2,1H3,(H,24,25)
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n/an/a 200n/an/an/an/an/an/a



Senomyx, Inc.

US Patent


Assay Description
In another embodiment, Fluorescence Polarization ("FP") based assays may be used to detect and monitor ligand binding. Fluorescence polarization is a...


US Patent US9247759 (2016)

More data for this
Ligand-Target Pair
Taste receptor type 2 member 14


(Homo sapiens (Human))
BDBM60947
PNG
(BDBM50443972 | US9247759, compound C)
Show SMILES COc1ccc(CN(Cc2ccccc2)S(=O)(=O)c2ccc(cc2)C(O)=O)cc1
Show InChI InChI=1S/C22H21NO5S/c1-28-20-11-7-18(8-12-20)16-23(15-17-5-3-2-4-6-17)29(26,27)21-13-9-19(10-14-21)22(24)25/h2-14H,15-16H2,1H3,(H,24,25)
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n/an/a 220n/an/an/an/an/an/a



Senomyx, Inc.

US Patent


Assay Description
In another embodiment, Fluorescence Polarization ("FP") based assays may be used to detect and monitor ligand binding. Fluorescence polarization is a...


US Patent US9247759 (2016)

More data for this
Ligand-Target Pair
Taste receptor type 2 member 14


(Homo sapiens (Human))
BDBM211101
PNG
(US9247759, 5-22)
Show SMILES OC(=O)C1CCC(CN(Cc2ccc(F)cc2)S(=O)(=O)c2ccccc2)CC1
Show InChI InChI=1S/C21H24FNO4S/c22-19-12-8-17(9-13-19)15-23(28(26,27)20-4-2-1-3-5-20)14-16-6-10-18(11-7-16)21(24)25/h1-5,8-9,12-13,16,18H,6-7,10-11,14-15H2,(H,24,25)
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Senomyx, Inc.

US Patent


Assay Description
In another embodiment, Fluorescence Polarization ("FP") based assays may be used to detect and monitor ligand binding. Fluorescence polarization is a...


US Patent US9247759 (2016)

More data for this
Ligand-Target Pair
Taste receptor type 2 member 14


(Homo sapiens (Human))
BDBM55311
PNG
(MLS000052401 | N-(1,3-benzodioxol-5-yl)-1,3-dimeth...)
Show SMILES Cn1c2ccc(cc2c(=O)n(C)c1=O)S(=O)(=O)Nc1ccc2OCOc2c1
Show InChI InChI=1S/C17H15N3O6S/c1-19-13-5-4-11(8-12(13)16(21)20(2)17(19)22)27(23,24)18-10-3-6-14-15(7-10)26-9-25-14/h3-8,18H,9H2,1-2H3
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Senomyx, Inc.

US Patent


Assay Description
In another embodiment, Fluorescence Polarization ("FP") based assays may be used to detect and monitor ligand binding. Fluorescence polarization is a...


US Patent US9247759 (2016)

More data for this
Ligand-Target Pair
Taste receptor type 2 member 14


(Homo sapiens (Human))
BDBM211237
PNG
(US9247759, 6-24)
Show SMILES Cc1nc(SCC(=O)N2CCCCC2)c2c(n1)n(C)c(=O)n(C)c2=O
Show InChI InChI=1S/C16H21N5O3S/c1-10-17-13-12(15(23)20(3)16(24)19(13)2)14(18-10)25-9-11(22)21-7-5-4-6-8-21/h4-9H2,1-3H3
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Senomyx, Inc.

US Patent


Assay Description
In another embodiment, Fluorescence Polarization ("FP") based assays may be used to detect and monitor ligand binding. Fluorescence polarization is a...


US Patent US9247759 (2016)

More data for this
Ligand-Target Pair
Taste receptor type 2 member 14


(Homo sapiens (Human))
BDBM211169
PNG
(US9247759, 5-115)
Show SMILES CCOC(=O)C1CCC(CN(Cc2ccccc2)S(=O)(=O)c2ccc(NC(C)=O)cc2)CC1
Show InChI InChI=1S/C25H32N2O5S/c1-3-32-25(29)22-11-9-21(10-12-22)18-27(17-20-7-5-4-6-8-20)33(30,31)24-15-13-23(14-16-24)26-19(2)28/h4-8,13-16,21-22H,3,9-12,17-18H2,1-2H3,(H,26,28)
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Senomyx, Inc.

US Patent


Assay Description
In another embodiment, Fluorescence Polarization ("FP") based assays may be used to detect and monitor ligand binding. Fluorescence polarization is a...


US Patent US9247759 (2016)

More data for this
Ligand-Target Pair
Taste receptor type 2 member 14


(Homo sapiens (Human))
BDBM211127
PNG
(US9247759, 5-51)
Show SMILES OC(=O)C1CCC(CN(Cc2ccc(F)cc2)S(=O)(=O)c2cccs2)CC1
Show InChI InChI=1S/C19H22FNO4S2/c20-17-9-5-15(6-10-17)13-21(27(24,25)18-2-1-11-26-18)12-14-3-7-16(8-4-14)19(22)23/h1-2,5-6,9-11,14,16H,3-4,7-8,12-13H2,(H,22,23)
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Senomyx, Inc.

US Patent


Assay Description
In another embodiment, Fluorescence Polarization ("FP") based assays may be used to detect and monitor ligand binding. Fluorescence polarization is a...


US Patent US9247759 (2016)

More data for this
Ligand-Target Pair
Taste receptor type 2 member 14


(Homo sapiens (Human))
BDBM211159
PNG
(US9247759, 5-101 | US9247759, 5-153)
Show SMILES COc1cccc(CN(Cc2ccc(cc2)C(O)=O)S(=O)(=O)c2ccccc2)c1
Show InChI InChI=1S/C22H21NO5S/c1-28-20-7-5-6-18(14-20)16-23(29(26,27)21-8-3-2-4-9-21)15-17-10-12-19(13-11-17)22(24)25/h2-14H,15-16H2,1H3,(H,24,25)
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Senomyx, Inc.

US Patent


Assay Description
In another embodiment, Fluorescence Polarization ("FP") based assays may be used to detect and monitor ligand binding. Fluorescence polarization is a...


US Patent US9247759 (2016)

More data for this
Ligand-Target Pair
Taste receptor type 2 member 14


(Homo sapiens (Human))
BDBM211159
PNG
(US9247759, 5-101 | US9247759, 5-153)
Show SMILES COc1cccc(CN(Cc2ccc(cc2)C(O)=O)S(=O)(=O)c2ccccc2)c1
Show InChI InChI=1S/C22H21NO5S/c1-28-20-7-5-6-18(14-20)16-23(29(26,27)21-8-3-2-4-9-21)15-17-10-12-19(13-11-17)22(24)25/h2-14H,15-16H2,1H3,(H,24,25)
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Senomyx, Inc.

US Patent


Assay Description
In another embodiment, Fluorescence Polarization ("FP") based assays may be used to detect and monitor ligand binding. Fluorescence polarization is a...


US Patent US9247759 (2016)

More data for this
Ligand-Target Pair
Taste receptor type 2 member 14


(Homo sapiens (Human))
BDBM50320146
PNG
(4-((N-benzyl-4-chlorophenylsulfonamido)methyl)benz...)
Show SMILES OC(=O)c1ccc(CN(Cc2ccccc2)S(=O)(=O)c2ccc(Cl)cc2)cc1
Show InChI InChI=1S/C21H18ClNO4S/c22-19-10-12-20(13-11-19)28(26,27)23(14-16-4-2-1-3-5-16)15-17-6-8-18(9-7-17)21(24)25/h1-13H,14-15H2,(H,24,25)
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Senomyx, Inc.

US Patent


Assay Description
In another embodiment, Fluorescence Polarization ("FP") based assays may be used to detect and monitor ligand binding. Fluorescence polarization is a...


US Patent US9247759 (2016)

More data for this
Ligand-Target Pair
Taste receptor type 2 member 14


(Homo sapiens (Human))
BDBM211162
PNG
(US9247759, 5-104 | US9247759, 5-156)
Show SMILES OC(=O)c1ccc(CN(Cc2cccc(F)c2)S(=O)(=O)c2ccccc2)cc1
Show InChI InChI=1S/C21H18FNO4S/c22-19-6-4-5-17(13-19)15-23(28(26,27)20-7-2-1-3-8-20)14-16-9-11-18(12-10-16)21(24)25/h1-13H,14-15H2,(H,24,25)
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n/an/a 406n/an/an/an/an/an/a



Senomyx, Inc.

US Patent


Assay Description
In another embodiment, Fluorescence Polarization ("FP") based assays may be used to detect and monitor ligand binding. Fluorescence polarization is a...


US Patent US9247759 (2016)

More data for this
Ligand-Target Pair
Taste receptor type 2 member 14


(Homo sapiens (Human))
BDBM211162
PNG
(US9247759, 5-104 | US9247759, 5-156)
Show SMILES OC(=O)c1ccc(CN(Cc2cccc(F)c2)S(=O)(=O)c2ccccc2)cc1
Show InChI InChI=1S/C21H18FNO4S/c22-19-6-4-5-17(13-19)15-23(28(26,27)20-7-2-1-3-8-20)14-16-9-11-18(12-10-16)21(24)25/h1-13H,14-15H2,(H,24,25)
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Senomyx, Inc.

US Patent


Assay Description
In another embodiment, Fluorescence Polarization ("FP") based assays may be used to detect and monitor ligand binding. Fluorescence polarization is a...


US Patent US9247759 (2016)

More data for this
Ligand-Target Pair
Taste receptor type 2 member 14


(Homo sapiens (Human))
BDBM211161
PNG
(US9247759, 5-103 | US9247759, 5-155)
Show SMILES OC(=O)c1ccc(CN(Cc2ccccc2F)S(=O)(=O)c2ccccc2)cc1
Show InChI InChI=1S/C21H18FNO4S/c22-20-9-5-4-6-18(20)15-23(28(26,27)19-7-2-1-3-8-19)14-16-10-12-17(13-11-16)21(24)25/h1-13H,14-15H2,(H,24,25)
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Senomyx, Inc.

US Patent


Assay Description
In another embodiment, Fluorescence Polarization ("FP") based assays may be used to detect and monitor ligand binding. Fluorescence polarization is a...


US Patent US9247759 (2016)

More data for this
Ligand-Target Pair
Taste receptor type 2 member 14


(Homo sapiens (Human))
BDBM211161
PNG
(US9247759, 5-103 | US9247759, 5-155)
Show SMILES OC(=O)c1ccc(CN(Cc2ccccc2F)S(=O)(=O)c2ccccc2)cc1
Show InChI InChI=1S/C21H18FNO4S/c22-20-9-5-4-6-18(20)15-23(28(26,27)19-7-2-1-3-8-19)14-16-10-12-17(13-11-16)21(24)25/h1-13H,14-15H2,(H,24,25)
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Senomyx, Inc.

US Patent


Assay Description
In another embodiment, Fluorescence Polarization ("FP") based assays may be used to detect and monitor ligand binding. Fluorescence polarization is a...


US Patent US9247759 (2016)

More data for this
Ligand-Target Pair
Taste receptor type 2 member 14


(Homo sapiens (Human))
BDBM211121
PNG
(US9247759, 5-45)
Show SMILES OC(=O)c1ccc(CN(Cc2cccc(F)c2)S(=O)(=O)c2ccc(O)cc2)cc1
Show InChI InChI=1S/C21H18FNO5S/c22-18-3-1-2-16(12-18)14-23(13-15-4-6-17(7-5-15)21(25)26)29(27,28)20-10-8-19(24)9-11-20/h1-12,24H,13-14H2,(H,25,26)
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Senomyx, Inc.

US Patent


Assay Description
In another embodiment, Fluorescence Polarization ("FP") based assays may be used to detect and monitor ligand binding. Fluorescence polarization is a...


US Patent US9247759 (2016)

More data for this
Ligand-Target Pair
Taste receptor type 2 member 14


(Homo sapiens (Human))
BDBM211180
PNG
(US9247759, 5-127)
Show SMILES Cc1ccc(cc1)S(=O)(=O)N(CC1CCC(CC1)C(O)=O)Cc1ccc(cc1)C#N
Show InChI InChI=1S/C23H26N2O4S/c1-17-2-12-22(13-3-17)30(28,29)25(15-19-6-4-18(14-24)5-7-19)16-20-8-10-21(11-9-20)23(26)27/h2-7,12-13,20-21H,8-11,15-16H2,1H3,(H,26,27)
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Senomyx, Inc.

US Patent


Assay Description
In another embodiment, Fluorescence Polarization ("FP") based assays may be used to detect and monitor ligand binding. Fluorescence polarization is a...


US Patent US9247759 (2016)

More data for this
Ligand-Target Pair
Taste receptor type 2 member 14


(Homo sapiens (Human))
BDBM211218
PNG
(US9247759, 6-2)
Show SMILES O=C(Nc1nnc(s1)-c1ccccc1)C(=C\c1ccco1)\C#N
Show InChI InChI=1S/C16H10N4O2S/c17-10-12(9-13-7-4-8-22-13)14(21)18-16-20-19-15(23-16)11-5-2-1-3-6-11/h1-9H,(H,18,20,21)/b12-9+
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Senomyx, Inc.

US Patent


Assay Description
In another embodiment, Fluorescence Polarization ("FP") based assays may be used to detect and monitor ligand binding. Fluorescence polarization is a...


US Patent US9247759 (2016)

More data for this
Ligand-Target Pair
Taste receptor type 2 member 14


(Homo sapiens (Human))
BDBM211081
PNG
(US9247759, 5-2)
Show SMILES COc1ccc(CN(Cc2ccco2)S(=O)(=O)c2ccc(cc2)C(O)=O)cc1
Show InChI InChI=1S/C20H19NO6S/c1-26-17-8-4-15(5-9-17)13-21(14-18-3-2-12-27-18)28(24,25)19-10-6-16(7-11-19)20(22)23/h2-12H,13-14H2,1H3,(H,22,23)
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Senomyx, Inc.

US Patent


Assay Description
In another embodiment, Fluorescence Polarization ("FP") based assays may be used to detect and monitor ligand binding. Fluorescence polarization is a...


US Patent US9247759 (2016)

More data for this
Ligand-Target Pair
Taste receptor type 2 member 14


(Homo sapiens (Human))
BDBM211173
PNG
(US9247759, 5-119)
Show SMILES CCOC(=O)C1CCC(CN(Cc2ccccc2)S(=O)(=O)c2ccc(Cl)cc2)CC1
Show InChI InChI=1S/C23H28ClNO4S/c1-2-29-23(26)20-10-8-19(9-11-20)17-25(16-18-6-4-3-5-7-18)30(27,28)22-14-12-21(24)13-15-22/h3-7,12-15,19-20H,2,8-11,16-17H2,1H3
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Senomyx, Inc.

US Patent


Assay Description
In another embodiment, Fluorescence Polarization ("FP") based assays may be used to detect and monitor ligand binding. Fluorescence polarization is a...


US Patent US9247759 (2016)

More data for this
Ligand-Target Pair
Taste receptor type 2 member 14


(Homo sapiens (Human))
BDBM211115
PNG
(US9247759, 5-39)
Show SMILES COc1ccc(CN(Cc2ccccc2)S(=O)(=O)c2ccc(cc2)C(O)=O)cc1OC
Show InChI InChI=1S/C23H23NO6S/c1-29-21-13-8-18(14-22(21)30-2)16-24(15-17-6-4-3-5-7-17)31(27,28)20-11-9-19(10-12-20)23(25)26/h3-14H,15-16H2,1-2H3,(H,25,26)
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Senomyx, Inc.

US Patent


Assay Description
In another embodiment, Fluorescence Polarization ("FP") based assays may be used to detect and monitor ligand binding. Fluorescence polarization is a...


US Patent US9247759 (2016)

More data for this
Ligand-Target Pair
Taste receptor type 2 member 14


(Homo sapiens (Human))
BDBM211221
PNG
(US9247759, 6-6)
Show SMILES Cn1c2ccc(cc2c(=O)n(C)c1=O)S(=O)(=O)Nc1ccc2OCCOc2c1
Show InChI InChI=1S/C18H17N3O6S/c1-20-14-5-4-12(10-13(14)17(22)21(2)18(20)23)28(24,25)19-11-3-6-15-16(9-11)27-8-7-26-15/h3-6,9-10,19H,7-8H2,1-2H3
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Senomyx, Inc.

US Patent


Assay Description
In another embodiment, Fluorescence Polarization ("FP") based assays may be used to detect and monitor ligand binding. Fluorescence polarization is a...


US Patent US9247759 (2016)

More data for this
Ligand-Target Pair
Taste receptor type 2 member 14


(Homo sapiens (Human))
BDBM211242
PNG
(US9247759, 6-29)
Show SMILES Cn1c2nccc(SCC(=O)NCc3ccccc3)c2c(=O)n(C)c1=O
Show InChI InChI=1S/C18H18N4O3S/c1-21-16-15(17(24)22(2)18(21)25)13(8-9-19-16)26-11-14(23)20-10-12-6-4-3-5-7-12/h3-9H,10-11H2,1-2H3,(H,20,23)
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n/an/a 710n/an/an/an/an/an/a



Senomyx, Inc.

US Patent


Assay Description
In another embodiment, Fluorescence Polarization ("FP") based assays may be used to detect and monitor ligand binding. Fluorescence polarization is a...


US Patent US9247759 (2016)

More data for this
Ligand-Target Pair
Taste receptor type 2 member 14


(Homo sapiens (Human))
BDBM211239
PNG
(US9247759, 6-26)
Show SMILES CCc1nc(SCC(=O)N2CCC(C)CC2)c2c(n1)n(C)c(=O)n(C)c2=O
Show InChI InChI=1S/C18H25N5O3S/c1-5-12-19-15-14(17(25)22(4)18(26)21(15)3)16(20-12)27-10-13(24)23-8-6-11(2)7-9-23/h11H,5-10H2,1-4H3
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Senomyx, Inc.

US Patent


Assay Description
In another embodiment, Fluorescence Polarization ("FP") based assays may be used to detect and monitor ligand binding. Fluorescence polarization is a...


US Patent US9247759 (2016)

More data for this
Ligand-Target Pair
Taste receptor type 2 member 14


(Homo sapiens (Human))
BDBM211240
PNG
(US9247759, 6-27)
Show SMILES CCOC(=O)N1CCN(CC1)C(=O)CSc1nc(CC)nc2n(C)c(=O)n(C)c(=O)c12
Show InChI InChI=1S/C19H26N6O5S/c1-5-12-20-15-14(17(27)23(4)18(28)22(15)3)16(21-12)31-11-13(26)24-7-9-25(10-8-24)19(29)30-6-2/h5-11H2,1-4H3
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Senomyx, Inc.

US Patent


Assay Description
In another embodiment, Fluorescence Polarization ("FP") based assays may be used to detect and monitor ligand binding. Fluorescence polarization is a...


US Patent US9247759 (2016)

More data for this
Ligand-Target Pair
Taste receptor type 2 member 14


(Homo sapiens (Human))
BDBM211177
PNG
(US9247759, 5-124)
Show SMILES CC(=O)Nc1ccc(cc1)S(=O)(=O)N(CC1CCC(CC1)C(O)=O)Cc1ccc(F)cc1
Show InChI InChI=1S/C23H27FN2O5S/c1-16(27)25-21-10-12-22(13-11-21)32(30,31)26(15-18-4-8-20(24)9-5-18)14-17-2-6-19(7-3-17)23(28)29/h4-5,8-13,17,19H,2-3,6-7,14-15H2,1H3,(H,25,27)(H,28,29)
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Senomyx, Inc.

US Patent


Assay Description
In another embodiment, Fluorescence Polarization ("FP") based assays may be used to detect and monitor ligand binding. Fluorescence polarization is a...


US Patent US9247759 (2016)

More data for this
Ligand-Target Pair
Taste receptor type 2 member 14


(Homo sapiens (Human))
BDBM211235
PNG
(US9247759, 6-22)
Show SMILES CCN(C)C(=O)CSc1nc(C)nc2n(C)c(=O)n(C)c(=O)c12
Show InChI InChI=1S/C14H19N5O3S/c1-6-17(3)9(20)7-23-12-10-11(15-8(2)16-12)18(4)14(22)19(5)13(10)21/h6-7H2,1-5H3
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Senomyx, Inc.

US Patent


Assay Description
In another embodiment, Fluorescence Polarization ("FP") based assays may be used to detect and monitor ligand binding. Fluorescence polarization is a...


US Patent US9247759 (2016)

More data for this
Ligand-Target Pair
Taste receptor type 2 member 14


(Homo sapiens (Human))
BDBM211163
PNG
(US9247759, 5-105 | US9247759, 5-157)
Show SMILES OC(=O)c1ccc(CN(Cc2ccc(F)cc2)S(=O)(=O)c2ccccc2)cc1
Show InChI InChI=1S/C21H18FNO4S/c22-19-12-8-17(9-13-19)15-23(28(26,27)20-4-2-1-3-5-20)14-16-6-10-18(11-7-16)21(24)25/h1-13H,14-15H2,(H,24,25)
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n/an/a 935n/an/an/an/an/an/a



Senomyx, Inc.

US Patent


Assay Description
In another embodiment, Fluorescence Polarization ("FP") based assays may be used to detect and monitor ligand binding. Fluorescence polarization is a...


US Patent US9247759 (2016)

More data for this
Ligand-Target Pair
Taste receptor type 2 member 14


(Homo sapiens (Human))
BDBM211163
PNG
(US9247759, 5-105 | US9247759, 5-157)
Show SMILES OC(=O)c1ccc(CN(Cc2ccc(F)cc2)S(=O)(=O)c2ccccc2)cc1
Show InChI InChI=1S/C21H18FNO4S/c22-19-12-8-17(9-13-19)15-23(28(26,27)20-4-2-1-3-5-20)14-16-6-10-18(11-7-16)21(24)25/h1-13H,14-15H2,(H,24,25)
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Senomyx, Inc.

US Patent


Assay Description
In another embodiment, Fluorescence Polarization ("FP") based assays may be used to detect and monitor ligand binding. Fluorescence polarization is a...


US Patent US9247759 (2016)

More data for this
Ligand-Target Pair
Taste receptor type 2 member 14


(Homo sapiens (Human))
BDBM211222
PNG
(US9247759, 6-18 | US9247759, 6-7)
Show SMILES Cc1c(F)cccc1NS(=O)(=O)c1ccc2n(C)c(=O)n(C)c(=O)c2c1
Show InChI InChI=1S/C17H16FN3O4S/c1-10-13(18)5-4-6-14(10)19-26(24,25)11-7-8-15-12(9-11)16(22)21(3)17(23)20(15)2/h4-9,19H,1-3H3
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Senomyx, Inc.

US Patent


Assay Description
In another embodiment, Fluorescence Polarization ("FP") based assays may be used to detect and monitor ligand binding. Fluorescence polarization is a...


US Patent US9247759 (2016)

More data for this
Ligand-Target Pair
Taste receptor type 2 member 14


(Homo sapiens (Human))
BDBM211222
PNG
(US9247759, 6-18 | US9247759, 6-7)
Show SMILES Cc1c(F)cccc1NS(=O)(=O)c1ccc2n(C)c(=O)n(C)c(=O)c2c1
Show InChI InChI=1S/C17H16FN3O4S/c1-10-13(18)5-4-6-14(10)19-26(24,25)11-7-8-15-12(9-11)16(22)21(3)17(23)20(15)2/h4-9,19H,1-3H3
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Senomyx, Inc.

US Patent


Assay Description
In another embodiment, Fluorescence Polarization ("FP") based assays may be used to detect and monitor ligand binding. Fluorescence polarization is a...


US Patent US9247759 (2016)

More data for this
Ligand-Target Pair
Taste receptor type 2 member 14


(Homo sapiens (Human))
BDBM211238
PNG
(US9247759, 6-25)
Show SMILES Cc1nc(SCC(=O)N2CCOCC2)c2c(n1)n(C)c(=O)n(C)c2=O
Show InChI InChI=1S/C15H19N5O4S/c1-9-16-12-11(14(22)19(3)15(23)18(12)2)13(17-9)25-8-10(21)20-4-6-24-7-5-20/h4-8H2,1-3H3
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n/an/a 1.01E+3n/an/an/an/an/an/a



Senomyx, Inc.

US Patent


Assay Description
In another embodiment, Fluorescence Polarization ("FP") based assays may be used to detect and monitor ligand binding. Fluorescence polarization is a...


US Patent US9247759 (2016)

More data for this
Ligand-Target Pair
Taste receptor type 2 member 14


(Homo sapiens (Human))
BDBM211117
PNG
(US9247759, 5-41)
Show SMILES COc1ccc(CN(Cc2ccc(OC)c(F)c2)S(=O)(=O)c2ccc(cc2)C(O)=O)cc1
Show InChI InChI=1S/C23H22FNO6S/c1-30-19-8-3-16(4-9-19)14-25(15-17-5-12-22(31-2)21(24)13-17)32(28,29)20-10-6-18(7-11-20)23(26)27/h3-13H,14-15H2,1-2H3,(H,26,27)
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n/an/a 1.11E+3n/an/an/an/an/an/a



Senomyx, Inc.

US Patent


Assay Description
In another embodiment, Fluorescence Polarization ("FP") based assays may be used to detect and monitor ligand binding. Fluorescence polarization is a...


US Patent US9247759 (2016)

More data for this
Ligand-Target Pair
Taste receptor type 2 member 14


(Homo sapiens (Human))
BDBM211213
PNG
(US9247759, 5-160)
Show SMILES COc1ccc(CN(Cc2ccc(F)cc2F)S(=O)(=O)c2ccc(cc2)C(O)=O)cc1
Show InChI InChI=1S/C22H19F2NO5S/c1-30-19-8-2-15(3-9-19)13-25(14-17-4-7-18(23)12-21(17)24)31(28,29)20-10-5-16(6-11-20)22(26)27/h2-12H,13-14H2,1H3,(H,26,27)
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n/an/a 1.26E+3n/an/an/an/an/an/a



Senomyx, Inc.

US Patent


Assay Description
In another embodiment, Fluorescence Polarization ("FP") based assays may be used to detect and monitor ligand binding. Fluorescence polarization is a...


US Patent US9247759 (2016)

More data for this
Ligand-Target Pair
Taste receptor type 2 member 14


(Homo sapiens (Human))
BDBM211158
PNG
(US9247759, 5-100 | US9247759, 5-152)
Show SMILES COc1ccccc1CN(Cc1ccc(cc1)C(O)=O)S(=O)(=O)c1ccccc1
Show InChI InChI=1S/C22H21NO5S/c1-28-21-10-6-5-7-19(21)16-23(29(26,27)20-8-3-2-4-9-20)15-17-11-13-18(14-12-17)22(24)25/h2-14H,15-16H2,1H3,(H,24,25)
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n/an/a 1.29E+3n/an/an/an/an/an/a



Senomyx, Inc.

US Patent


Assay Description
In another embodiment, Fluorescence Polarization ("FP") based assays may be used to detect and monitor ligand binding. Fluorescence polarization is a...


US Patent US9247759 (2016)

More data for this
Ligand-Target Pair
Taste receptor type 2 member 14


(Homo sapiens (Human))
BDBM211158
PNG
(US9247759, 5-100 | US9247759, 5-152)
Show SMILES COc1ccccc1CN(Cc1ccc(cc1)C(O)=O)S(=O)(=O)c1ccccc1
Show InChI InChI=1S/C22H21NO5S/c1-28-21-10-6-5-7-19(21)16-23(29(26,27)20-8-3-2-4-9-20)15-17-11-13-18(14-12-17)22(24)25/h2-14H,15-16H2,1H3,(H,24,25)
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Senomyx, Inc.

US Patent


Assay Description
In another embodiment, Fluorescence Polarization ("FP") based assays may be used to detect and monitor ligand binding. Fluorescence polarization is a...


US Patent US9247759 (2016)

More data for this
Ligand-Target Pair
Taste receptor type 2 member 14


(Homo sapiens (Human))
BDBM211155
PNG
(US9247759, 5-149 | US9247759, 5-95)
Show SMILES COc1ccc(CN(C(C)c2ccccc2)S(=O)(=O)c2ccc(cc2)C(O)=O)cc1
Show InChI InChI=1/C23H23NO5S/c1-17(19-6-4-3-5-7-19)24(16-18-8-12-21(29-2)13-9-18)30(27,28)22-14-10-20(11-15-22)23(25)26/h3-15,17H,16H2,1-2H3,(H,25,26)
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n/an/a 1.40E+3n/an/an/an/an/an/a



Senomyx, Inc.

US Patent


Assay Description
In another embodiment, Fluorescence Polarization ("FP") based assays may be used to detect and monitor ligand binding. Fluorescence polarization is a...


US Patent US9247759 (2016)

More data for this
Ligand-Target Pair
Taste receptor type 2 member 14


(Homo sapiens (Human))
BDBM211155
PNG
(US9247759, 5-149 | US9247759, 5-95)
Show SMILES COc1ccc(CN(C(C)c2ccccc2)S(=O)(=O)c2ccc(cc2)C(O)=O)cc1
Show InChI InChI=1/C23H23NO5S/c1-17(19-6-4-3-5-7-19)24(16-18-8-12-21(29-2)13-9-18)30(27,28)22-14-10-20(11-15-22)23(25)26/h3-15,17H,16H2,1-2H3,(H,25,26)
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Senomyx, Inc.

US Patent


Assay Description
In another embodiment, Fluorescence Polarization ("FP") based assays may be used to detect and monitor ligand binding. Fluorescence polarization is a...


US Patent US9247759 (2016)

More data for this
Ligand-Target Pair
Taste receptor type 2 member 14


(Homo sapiens (Human))
BDBM211116
PNG
(US9247759, 5-40)
Show SMILES COc1ccc(CN(Cc2ccc(OC)c(OC)c2)S(=O)(=O)c2ccc(cc2)C(O)=O)cc1
Show InChI InChI=1S/C24H25NO7S/c1-30-20-9-4-17(5-10-20)15-25(16-18-6-13-22(31-2)23(14-18)32-3)33(28,29)21-11-7-19(8-12-21)24(26)27/h4-14H,15-16H2,1-3H3,(H,26,27)
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n/an/a 1.47E+3n/an/an/an/an/an/a



Senomyx, Inc.

US Patent


Assay Description
In another embodiment, Fluorescence Polarization ("FP") based assays may be used to detect and monitor ligand binding. Fluorescence polarization is a...


US Patent US9247759 (2016)

More data for this
Ligand-Target Pair
Taste receptor type 2 member 14


(Homo sapiens (Human))
BDBM211100
PNG
(US9247759, 5-21)
Show SMILES CC(=O)Nc1ccc(cc1)S(=O)(=O)N(CC1CCC(CC1)C(O)=O)Cc1ccccc1
Show InChI InChI=1S/C23H28N2O5S/c1-17(26)24-21-11-13-22(14-12-21)31(29,30)25(15-18-5-3-2-4-6-18)16-19-7-9-20(10-8-19)23(27)28/h2-6,11-14,19-20H,7-10,15-16H2,1H3,(H,24,26)(H,27,28)
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n/an/a 1.62E+3n/an/an/an/an/an/a



Senomyx, Inc.

US Patent


Assay Description
In another embodiment, Fluorescence Polarization ("FP") based assays may be used to detect and monitor ligand binding. Fluorescence polarization is a...


US Patent US9247759 (2016)

More data for this
Ligand-Target Pair
Taste receptor type 2 member 14


(Homo sapiens (Human))
BDBM211126
PNG
(US9247759, 5-50)
Show SMILES COc1ccc(CN(Cc2ccc(F)c(OC)c2)S(=O)(=O)c2ccc(cc2)C(O)=O)cc1
Show InChI InChI=1S/C23H22FNO6S/c1-30-19-8-3-16(4-9-19)14-25(15-17-5-12-21(24)22(13-17)31-2)32(28,29)20-10-6-18(7-11-20)23(26)27/h3-13H,14-15H2,1-2H3,(H,26,27)
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n/an/a 1.65E+3n/an/an/an/an/an/a



Senomyx, Inc.

US Patent


Assay Description
In another embodiment, Fluorescence Polarization ("FP") based assays may be used to detect and monitor ligand binding. Fluorescence polarization is a...


US Patent US9247759 (2016)

More data for this
Ligand-Target Pair
Taste receptor type 2 member 14


(Homo sapiens (Human))
BDBM211178
PNG
(US9247759, 5-125)
Show SMILES Nc1ccc(cc1)S(=O)(=O)N(CC1CCC(CC1)C(O)=O)Cc1ccc(F)cc1
Show InChI InChI=1S/C21H25FN2O4S/c22-18-7-3-16(4-8-18)14-24(13-15-1-5-17(6-2-15)21(25)26)29(27,28)20-11-9-19(23)10-12-20/h3-4,7-12,15,17H,1-2,5-6,13-14,23H2,(H,25,26)
UniProtKB/SwissProt

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US Patent
n/an/a 1.65E+3n/an/an/an/an/an/a



Senomyx, Inc.

US Patent


Assay Description
In another embodiment, Fluorescence Polarization ("FP") based assays may be used to detect and monitor ligand binding. Fluorescence polarization is a...


US Patent US9247759 (2016)

More data for this
Ligand-Target Pair
Taste receptor type 2 member 14


(Homo sapiens (Human))
BDBM211223
PNG
(US9247759, 6-20 | US9247759, 6-9)
Show SMILES Cc1ccccc1NS(=O)(=O)c1ccc2n(C)c(=O)n(C)c(=O)c2c1
Show InChI InChI=1S/C17H17N3O4S/c1-11-6-4-5-7-14(11)18-25(23,24)12-8-9-15-13(10-12)16(21)20(3)17(22)19(15)2/h4-10,18H,1-3H3
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UniChem
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US Patent
n/an/a 1.73E+3n/an/an/an/an/an/a



Senomyx, Inc.

US Patent


Assay Description
In another embodiment, Fluorescence Polarization ("FP") based assays may be used to detect and monitor ligand binding. Fluorescence polarization is a...


US Patent US9247759 (2016)

More data for this
Ligand-Target Pair
Taste receptor type 2 member 14


(Homo sapiens (Human))
BDBM211223
PNG
(US9247759, 6-20 | US9247759, 6-9)
Show SMILES Cc1ccccc1NS(=O)(=O)c1ccc2n(C)c(=O)n(C)c(=O)c2c1
Show InChI InChI=1S/C17H17N3O4S/c1-11-6-4-5-7-14(11)18-25(23,24)12-8-9-15-13(10-12)16(21)20(3)17(22)19(15)2/h4-10,18H,1-3H3
UniProtKB/SwissProt

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AffyNet 
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PC cid
PC sid
UniChem
AffyNet 
US Patent
n/an/a 1.73E+3n/an/an/an/an/an/a



Senomyx, Inc.

US Patent


Assay Description
In another embodiment, Fluorescence Polarization ("FP") based assays may be used to detect and monitor ligand binding. Fluorescence polarization is a...


US Patent US9247759 (2016)

More data for this
Ligand-Target Pair
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