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Found 28 hits Enz. Inhib. hit(s) with Target = 'Thyroid Hormone Receptor (TR-alpha)' AND taxid = 9031   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Thyroid Hormone Receptor (TR-alpha)


(Gallus gallus (chicken))
BDBM18959
PNG
(3-{[4-(2-aminoethoxy)-3,5-diiodophenyl]carbonyl}-2...)
Show SMILES CCCCc1oc2ccccc2c1C(=O)c1cc(I)c(OCCN)c(I)c1
Show InChI InChI=1S/C21H21I2NO3/c1-2-3-7-18-19(14-6-4-5-8-17(14)27-18)20(25)13-11-15(22)21(16(23)12-13)26-10-9-24/h4-6,8,11-12H,2-3,7,9-10,24H2,1H3
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PubMed
n/an/a 3.70E+4n/an/an/an/a7.622



University of Amsterdam



Assay Description
IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha.


Citation and Details
More data for this
Ligand-Target Pair
Thyroid Hormone Receptor (TR-alpha)


(Gallus gallus (chicken))
BDBM18962
PNG
(4-[(2-butyl-1-benzofuran-3-yl)carbonyl]-2,6-diiodo...)
Show SMILES CCCCc1oc2ccccc2c1C(=O)c1cc(I)c(O)c(I)c1
Show InChI InChI=1S/C19H16I2O3/c1-2-3-7-16-17(12-6-4-5-8-15(12)24-16)18(22)11-9-13(20)19(23)14(21)10-11/h4-6,8-10,23H,2-3,7H2,1H3
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n/an/a 3.80E+4n/an/an/an/a7.622



University of Amsterdam



Assay Description
IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha.


Citation and Details
More data for this
Ligand-Target Pair
Thyroid Hormone Receptor (TR-alpha)


(Gallus gallus (chicken))
BDBM18958
PNG
((2-{4-[(2-butyl-1-benzofuran-3-yl)carbonyl]-2,6-di...)
Show SMILES CCCCc1oc2ccccc2c1C(=O)c1cc(I)c(OCCNCC)c(I)c1
Show InChI InChI=1S/C23H25I2NO3/c1-3-5-9-20-21(16-8-6-7-10-19(16)29-20)22(27)15-13-17(24)23(18(25)14-15)28-12-11-26-4-2/h6-8,10,13-14,26H,3-5,9,11-12H2,1-2H3
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n/an/a 4.70E+4n/an/an/an/a7.622



University of Amsterdam



Assay Description
IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha.


Citation and Details
More data for this
Ligand-Target Pair
Thyroid Hormone Receptor (TR-alpha)


(Gallus gallus (chicken))
BDBM18963
PNG
(4-[(2-butyl-1-benzofuran-3-yl)carbonyl]-2-iodophen...)
Show SMILES CCCCc1oc2ccccc2c1C(=O)c1ccc(O)c(I)c1
Show InChI InChI=1S/C19H17IO3/c1-2-3-7-17-18(13-6-4-5-8-16(13)23-17)19(22)12-9-10-15(21)14(20)11-12/h4-6,8-11,21H,2-3,7H2,1H3
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n/an/a 1.13E+5n/an/an/an/a7.622



University of Amsterdam



Assay Description
IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha.


Citation and Details
More data for this
Ligand-Target Pair
Thyroid Hormone Receptor (TR-alpha)


(Gallus gallus (chicken))
BDBM18961
PNG
((2-{4-[(2-butyl-1-benzofuran-3-yl)carbonyl]phenoxy...)
Show SMILES CCCCc1oc2ccccc2c1C(=O)c1ccc(OCCN(CC)CC)cc1
Show InChI InChI=1S/C25H31NO3/c1-4-7-11-23-24(21-10-8-9-12-22(21)29-23)25(27)19-13-15-20(16-14-19)28-18-17-26(5-2)6-3/h8-10,12-16H,4-7,11,17-18H2,1-3H3
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n/an/a 1.62E+5n/an/an/an/a7.622



University of Amsterdam



Assay Description
IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha.


Citation and Details
More data for this
Ligand-Target Pair
Thyroid Hormone Receptor (TR-alpha)


(Gallus gallus (chicken))
BDBM18960
PNG
((2-{4-[(2-butyl-1-benzofuran-3-yl)carbonyl]-2-iodo...)
Show SMILES CCCCc1oc2ccccc2c1C(=O)c1ccc(OCCN(CC)CC)c(I)c1
Show InChI InChI=1S/C25H30INO3/c1-4-7-11-23-24(19-10-8-9-12-21(19)30-23)25(28)18-13-14-22(20(26)17-18)29-16-15-27(5-2)6-3/h8-10,12-14,17H,4-7,11,15-16H2,1-3H3
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n/an/a>2.00E+5n/an/an/an/a7.622



University of Amsterdam



Assay Description
IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha.


Citation and Details
More data for this
Ligand-Target Pair
Thyroid Hormone Receptor (TR-alpha)


(Gallus gallus (chicken))
BDBM18957
PNG
((2-{4-[(2-butyl-1-benzofuran-3-yl)carbonyl]-2,6-di...)
Show SMILES CCCCc1oc2ccccc2c1C(=O)c1cc(I)c(OCCN(CC)CC)c(I)c1
Show InChI InChI=1S/C25H29I2NO3/c1-4-7-11-22-23(18-10-8-9-12-21(18)31-22)24(29)17-15-19(26)25(20(27)16-17)30-14-13-28(5-2)6-3/h8-10,12,15-16H,4-7,11,13-14H2,1-3H3
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n/an/a>2.00E+5n/an/an/an/a7.622



University of Amsterdam



Assay Description
IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha.


Citation and Details
More data for this
Ligand-Target Pair
Thyroid Hormone Receptor (TR-alpha)


(Gallus gallus (chicken))
BDBM18964
PNG
(4-[(2-butyl-1-benzofuran-3-yl)carbonyl]phenol | L ...)
Show SMILES CCCCc1oc2ccccc2c1C(=O)c1ccc(O)cc1
Show InChI InChI=1S/C19H18O3/c1-2-3-7-17-18(15-6-4-5-8-16(15)22-17)19(21)13-9-11-14(20)12-10-13/h4-6,8-12,20H,2-3,7H2,1H3
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n/an/a>2.00E+6n/an/an/an/a7.622



University of Amsterdam



Assay Description
IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha.


Citation and Details
More data for this
Ligand-Target Pair
Thyroid Hormone Receptor (TR-alpha)/(TR-beta)


(Homo sapiens (human))
BDBM50163903
PNG
(CHEMBL180819 | N-{4-[3-(4-Fluoro-phenoxy)-1H-indol...)
Show SMILES CCOC(=O)C(=O)Nc1cc(c(Oc2ccc3[nH]cc(Oc4ccc(F)cc4)c3c2)c(c1)C(F)(F)F)C(F)(F)F
Show InChI InChI=1S/C26H17F7N2O5/c1-2-38-24(37)23(36)35-14-9-18(25(28,29)30)22(19(10-14)26(31,32)33)40-16-7-8-20-17(11-16)21(12-34-20)39-15-5-3-13(27)4-6-15/h3-12,34H,2H2,1H3,(H,35,36)
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n/an/an/an/a 495n/an/an/an/a



BAYER HealthCare AG

Curated by ChEMBL


Assay Description
Agonist activity towards thyroid hormone receptor expressed in human HepG2 cells


Citation and Details
More data for this
Ligand-Target Pair
Thyroid Hormone Receptor (TR-alpha)/(TR-beta)


(Homo sapiens (human))
BDBM50163894
PNG
(CHEMBL183863 | N-{4-[3-(4-Fluoro-benzyl)-1H-indol-...)
Show SMILES CCOC(=O)C(=O)Nc1cc(c(Oc2ccc3[nH]cc(Cc4ccc(F)cc4)c3c2)c(c1)C(F)(F)F)C(F)(F)F
Show InChI InChI=1S/C27H19F7N2O4/c1-2-39-25(38)24(37)36-17-10-20(26(29,30)31)23(21(11-17)27(32,33)34)40-18-7-8-22-19(12-18)15(13-35-22)9-14-3-5-16(28)6-4-14/h3-8,10-13,35H,2,9H2,1H3,(H,36,37)
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BAYER HealthCare AG

Curated by ChEMBL


Assay Description
Agonist activity towards thyroid hormone receptor expressed in human HepG2 cells


Citation and Details
More data for this
Ligand-Target Pair
Thyroid Hormone Receptor (TR-alpha)/(TR-beta)


(Homo sapiens (human))
BDBM50163896
PNG
(CHEMBL183000 | N-[4-(3-Isopropyl-1H-indol-5-yloxy)...)
Show SMILES CCOC(=O)C(=O)Nc1cc(C=C)c(Oc2ccc3[nH]cc(C(C)C)c3c2)c(C=C)c1
Show InChI InChI=1S/C25H26N2O4/c1-6-16-11-18(27-24(28)25(29)30-8-3)12-17(7-2)23(16)31-19-9-10-22-20(13-19)21(14-26-22)15(4)5/h6-7,9-15,26H,1-2,8H2,3-5H3,(H,27,28)
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n/an/an/an/a 7.80n/an/an/an/a



BAYER HealthCare AG

Curated by ChEMBL


Assay Description
Agonist activity towards thyroid hormone receptor expressed in human HepG2 cells


Citation and Details
More data for this
Ligand-Target Pair
Thyroid Hormone Receptor (TR-alpha)/(TR-beta)


(Homo sapiens (human))
BDBM50163898
PNG
(CHEMBL359647 | N-[3-Chloro-4-(3-isopropyl-1H-indol...)
Show SMILES CCOC(=O)C(=O)Nc1cc(C)c(Oc2ccc3[nH]cc(C(C)C)c3c2)c(Cl)c1
Show InChI InChI=1S/C22H23ClN2O4/c1-5-28-22(27)21(26)25-14-8-13(4)20(18(23)9-14)29-15-6-7-19-16(10-15)17(11-24-19)12(2)3/h6-12,24H,5H2,1-4H3,(H,25,26)
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BAYER HealthCare AG

Curated by ChEMBL


Assay Description
Agonist activity towards thyroid hormone receptor expressed in human HepG2 cells


Citation and Details
More data for this
Ligand-Target Pair
Thyroid Hormone Receptor (TR-alpha)/(TR-beta)


(Homo sapiens (human))
BDBM50163897
PNG
(3-[4-(3-Isopropyl-1H-indol-5-yloxy)-3,5-bis-triflu...)
Show SMILES CC(C)c1c[nH]c2ccc(Oc3c(cc(CCC(O)=O)cc3C(F)(F)F)C(F)(F)F)cc12
Show InChI InChI=1S/C22H19F6NO3/c1-11(2)15-10-29-18-5-4-13(9-14(15)18)32-20-16(21(23,24)25)7-12(3-6-19(30)31)8-17(20)22(26,27)28/h4-5,7-11,29H,3,6H2,1-2H3,(H,30,31)
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n/an/an/an/a 2.60n/an/an/an/a



BAYER HealthCare AG

Curated by ChEMBL


Assay Description
Agonist activity towards thyroid hormone receptor expressed in human HepG2 cells


Citation and Details
More data for this
Ligand-Target Pair
Thyroid Hormone Receptor (TR-alpha)/(TR-beta)


(Homo sapiens (human))
BDBM50163902
PNG
(CHEMBL183727 | N-[3,5-Dichloro-4-(1H-indol-5-yloxy...)
Show SMILES CCOC(=O)C(=O)Nc1cc(Cl)c(Oc2ccc3[nH]ccc3c2)c(Cl)c1
Show InChI InChI=1S/C18H14Cl2N2O4/c1-2-25-18(24)17(23)22-11-8-13(19)16(14(20)9-11)26-12-3-4-15-10(7-12)5-6-21-15/h3-9,21H,2H2,1H3,(H,22,23)
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n/an/an/an/a 15n/an/an/an/a



BAYER HealthCare AG

Curated by ChEMBL


Assay Description
Agonist activity towards thyroid hormone receptor expressed in human HepG2 cells


Citation and Details
More data for this
Ligand-Target Pair
Thyroid Hormone Receptor (TR-alpha)/(TR-beta)


(Homo sapiens (human))
BDBM50163899
PNG
(CHEMBL183122 | N-[3,5-Dichloro-4-(3-isopropyl-1H-i...)
Show SMILES COC(=O)C(=O)Nc1cc(Cl)c(Oc2ccc3[nH]cc(C(C)C)c3c2)c(Cl)c1
Show InChI InChI=1S/C20H18Cl2N2O4/c1-10(2)14-9-23-17-5-4-12(8-13(14)17)28-18-15(21)6-11(7-16(18)22)24-19(25)20(26)27-3/h4-10,23H,1-3H3,(H,24,25)
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BAYER HealthCare AG

Curated by ChEMBL


Assay Description
Agonist activity towards thyroid hormone receptor expressed in human HepG2 cells


Citation and Details
More data for this
Ligand-Target Pair
Thyroid Hormone Receptor (TR-alpha)/(TR-beta)


(Homo sapiens (human))
BDBM50163900
PNG
((E)-3-[4-(3-Isopropyl-1H-indol-5-yloxy)-3,5-bis-tr...)
Show SMILES CC(C)c1c[nH]c2ccc(Oc3c(cc(\C=C\C(O)=O)cc3C(F)(F)F)C(F)(F)F)cc12
Show InChI InChI=1S/C22H17F6NO3/c1-11(2)15-10-29-18-5-4-13(9-14(15)18)32-20-16(21(23,24)25)7-12(3-6-19(30)31)8-17(20)22(26,27)28/h3-11,29H,1-2H3,(H,30,31)/b6-3+
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BAYER HealthCare AG

Curated by ChEMBL


Assay Description
Agonist activity towards thyroid hormone receptor expressed in human HepG2 cells


Citation and Details
More data for this
Ligand-Target Pair
Thyroid Hormone Receptor (TR-alpha)/(TR-beta)


(Homo sapiens (human))
BDBM50163901
PNG
(CHEMBL360137 | N-[3,5-Dibromo-4-(3-isopropyl-1H-in...)
Show SMILES CCOC(=O)C(=O)Nc1cc(Br)c(Oc2ccc3[nH]cc(C(C)C)c3c2)c(Br)c1
Show InChI InChI=1S/C21H20Br2N2O4/c1-4-28-21(27)20(26)25-12-7-16(22)19(17(23)8-12)29-13-5-6-18-14(9-13)15(10-24-18)11(2)3/h5-11,24H,4H2,1-3H3,(H,25,26)
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n/an/an/an/a 1.20n/an/an/an/a



BAYER HealthCare AG

Curated by ChEMBL


Assay Description
Agonist activity towards thyroid hormone receptor expressed in human HepG2 cells


Citation and Details
More data for this
Ligand-Target Pair
Thyroid Hormone Receptor (TR-alpha)/(TR-beta)


(Homo sapiens (human))
BDBM50163904
PNG
(CHEMBL180952 | N-[4-(3-Isopropyl-1H-indol-5-ylmeth...)
Show SMILES CCOC(=O)C(=O)Nc1cc(C)c(Cc2ccc3[nH]cc(C(C)C)c3c2)c(C)c1
Show InChI InChI=1S/C24H28N2O3/c1-6-29-24(28)23(27)26-18-9-15(4)19(16(5)10-18)11-17-7-8-22-20(12-17)21(13-25-22)14(2)3/h7-10,12-14,25H,6,11H2,1-5H3,(H,26,27)
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BAYER HealthCare AG

Curated by ChEMBL


Assay Description
Agonist activity towards thyroid hormone receptor expressed in human HepG2 cells


Citation and Details
More data for this
Ligand-Target Pair
Thyroid Hormone Receptor (TR-alpha)/(TR-beta)


(Homo sapiens (human))
BDBM50163905
PNG
(CHEMBL183829 | N-[4-(1H-Indol-5-yloxy)-3,5-dimethy...)
Show SMILES CCOC(=O)C(=O)Nc1cc(C)c(Oc2ccc3[nH]ccc3c2)c(C)c1
Show InChI InChI=1S/C20H20N2O4/c1-4-25-20(24)19(23)22-15-9-12(2)18(13(3)10-15)26-16-5-6-17-14(11-16)7-8-21-17/h5-11,21H,4H2,1-3H3,(H,22,23)
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n/an/an/an/a 72n/an/an/an/a



BAYER HealthCare AG

Curated by ChEMBL


Assay Description
Agonist activity towards thyroid hormone receptor expressed in human HepG2 cells


Citation and Details
More data for this
Ligand-Target Pair
Thyroid Hormone Receptor (TR-alpha)/(TR-beta)


(Homo sapiens (human))
BDBM50163895
PNG
((S)-2-Amino-3-[4-(4-hydroxy-3-iodo-phenoxy)-3-iodo...)
Show SMILES Cc1cc(C[C@H](N)C(O)=O)cc(I)c1Oc1ccc(O)c(I)c1
Show InChI InChI=1S/C16H15I2NO4/c1-8-4-9(6-13(19)16(21)22)5-12(18)15(8)23-10-2-3-14(20)11(17)7-10/h2-5,7,13,20H,6,19H2,1H3,(H,21,22)/t13-/m0/s1
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n/an/an/an/a 0.200n/an/an/an/a



BAYER HealthCare AG

Curated by ChEMBL


Assay Description
Agonist activity towards thyroid hormone receptor expressed in human HepG2 cells


Citation and Details
More data for this
Ligand-Target Pair
Thyroid Hormone Receptor (TR-alpha)/(TR-beta)


(Homo sapiens (human))
BDBM50163893
PNG
(CHEMBL183057 | N-[3,5-Dimethyl-4-(3-methyl-1H-indo...)
Show SMILES CCOC(=O)C(=O)Nc1cc(C)c(Oc2ccc3[nH]cc(C)c3c2)c(C)c1
Show InChI InChI=1S/C21H22N2O4/c1-5-26-21(25)20(24)23-15-8-12(2)19(13(3)9-15)27-16-6-7-18-17(10-16)14(4)11-22-18/h6-11,22H,5H2,1-4H3,(H,23,24)
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BAYER HealthCare AG

Curated by ChEMBL


Assay Description
Agonist activity towards thyroid hormone receptor expressed in human HepG2 cells


Citation and Details
More data for this
Ligand-Target Pair
Thyroid Hormone Receptor (TR-alpha)/(TR-beta)


(Homo sapiens (human))
BDBM50163906
PNG
(CHEMBL361162 | [4-(3-Isopropyl-1H-indol-5-yloxy)-3...)
Show SMILES CC(C)c1c[nH]c2ccc(Oc3c(cc(CC(O)=O)cc3C(F)(F)F)C(F)(F)F)cc12
Show InChI InChI=1S/C21H17F6NO3/c1-10(2)14-9-28-17-4-3-12(8-13(14)17)31-19-15(20(22,23)24)5-11(7-18(29)30)6-16(19)21(25,26)27/h3-6,8-10,28H,7H2,1-2H3,(H,29,30)
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n/an/an/an/a 0.5n/an/an/an/a



BAYER HealthCare AG

Curated by ChEMBL


Assay Description
Agonist activity towards thyroid hormone receptor expressed in human HepG2 cells


Citation and Details
More data for this
Ligand-Target Pair
Thyroid Hormone Receptor (TR-alpha)/(TR-beta)


(Homo sapiens (human))
BDBM50163891
PNG
(CHEMBL360774 | N-{4-[3-(4-Fluoro-phenyl)-1H-indol-...)
Show SMILES CCOC(=O)C(=O)Nc1cc(c(Oc2ccc3[nH]cc(-c4ccc(F)cc4)c3c2)c(c1)C(F)(F)F)C(F)(F)F
Show InChI InChI=1S/C26H17F7N2O4/c1-2-38-24(37)23(36)35-15-9-19(25(28,29)30)22(20(10-15)26(31,32)33)39-16-7-8-21-17(11-16)18(12-34-21)13-3-5-14(27)6-4-13/h3-12,34H,2H2,1H3,(H,35,36)
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n/an/an/an/a 115n/an/an/an/a



BAYER HealthCare AG

Curated by ChEMBL


Assay Description
Agonist activity towards thyroid hormone receptor expressed in human HepG2 cells


Citation and Details
More data for this
Ligand-Target Pair
Thyroid Hormone Receptor (TR-alpha)/(TR-beta)


(Homo sapiens (human))
BDBM50163890
PNG
(CHEMBL183050 | N-[4-(3-Isopropyl-1H-indol-5-yloxy)...)
Show SMILES CCOC(=O)C(=O)Nc1cc(C)c(Oc2ccc3[nH]cc(C(C)C)c3c2)c(C)c1
Show InChI InChI=1S/C23H26N2O4/c1-6-28-23(27)22(26)25-16-9-14(4)21(15(5)10-16)29-17-7-8-20-18(11-17)19(12-24-20)13(2)3/h7-13,24H,6H2,1-5H3,(H,25,26)
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n/an/an/an/a 4n/an/an/an/a



BAYER HealthCare AG

Curated by ChEMBL


Assay Description
Agonist activity towards thyroid hormone receptor expressed in human HepG2 cells


Citation and Details
More data for this
Ligand-Target Pair
Thyroid Hormone Receptor (TR-alpha)/(TR-beta)


(Homo sapiens (human))
BDBM50163889
PNG
(CHEMBL182430 | N-[3-Chloro-4-(3-isopropyl-1H-indol...)
Show SMILES CCOC(=O)CC(=O)Nc1cc(C)c(Oc2ccc3[nH]cc(C(C)C)c3c2)c(Cl)c1
Show InChI InChI=1S/C23H25ClN2O4/c1-5-29-22(28)11-21(27)26-15-8-14(4)23(19(24)9-15)30-16-6-7-20-17(10-16)18(12-25-20)13(2)3/h6-10,12-13,25H,5,11H2,1-4H3,(H,26,27)
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n/an/an/an/a 8n/an/an/an/a



BAYER HealthCare AG

Curated by ChEMBL


Assay Description
Agonist activity towards thyroid hormone receptor expressed in human HepG2 cells


Citation and Details
More data for this
Ligand-Target Pair
Thyroid Hormone Receptor (TR-alpha)/(TR-beta)


(Homo sapiens (human))
BDBM50163888
PNG
(CHEMBL183176 | N-[4-(3-Isopropyl-1H-indol-5-yloxy)...)
Show SMILES CCOC(=O)C(=O)Nc1cc(c(Oc2ccc3[nH]cc(C(C)C)c3c2)c(c1)C(F)(F)F)C(F)(F)F
Show InChI InChI=1S/C23H20F6N2O4/c1-4-34-21(33)20(32)31-12-7-16(22(24,25)26)19(17(8-12)23(27,28)29)35-13-5-6-18-14(9-13)15(10-30-18)11(2)3/h5-11,30H,4H2,1-3H3,(H,31,32)
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n/an/an/an/a 3n/an/an/an/a



BAYER HealthCare AG

Curated by ChEMBL


Assay Description
Agonist activity towards thyroid hormone receptor expressed in human HepG2 cells


Citation and Details
More data for this
Ligand-Target Pair
Thyroid Hormone Receptor (TR-alpha)/(TR-beta)


(Homo sapiens (human))
BDBM50163887
PNG
(CHEMBL183565 | N-[4-(1H-Indol-5-yloxy)-3,5-bis-tri...)
Show SMILES CCOC(=O)C(=O)Nc1cc(c(Oc2ccc3[nH]ccc3c2)c(c1)C(F)(F)F)C(F)(F)F
Show InChI InChI=1S/C20H14F6N2O4/c1-2-31-18(30)17(29)28-11-8-13(19(21,22)23)16(14(9-11)20(24,25)26)32-12-3-4-15-10(7-12)5-6-27-15/h3-9,27H,2H2,1H3,(H,28,29)
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n/an/an/an/a 23n/an/an/an/a



BAYER HealthCare AG

Curated by ChEMBL


Assay Description
Agonist activity towards thyroid hormone receptor expressed in human HepG2 cells


Citation and Details
More data for this
Ligand-Target Pair
Thyroid Hormone Receptor (TR-alpha)/(TR-beta)


(Homo sapiens (human))
BDBM50163892
PNG
(CHEMBL183851 | N-[3,5-Dimethyl-4-(3-pentyl-1H-inda...)
Show SMILES CCCCCc1n[nH]c2ccc(Oc3c(C)cc(NC(=O)C(=O)OCC)cc3C)cc12
Show InChI InChI=1S/C24H29N3O4/c1-5-7-8-9-20-19-14-18(10-11-21(19)27-26-20)31-22-15(3)12-17(13-16(22)4)25-23(28)24(29)30-6-2/h10-14H,5-9H2,1-4H3,(H,25,28)(H,26,27)
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n/an/an/an/a 8n/an/an/an/a



BAYER HealthCare AG

Curated by ChEMBL


Assay Description
Agonist activity towards thyroid hormone receptor expressed in human HepG2 cells


Citation and Details
More data for this
Ligand-Target Pair