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Compile Data Set for Download or QSAR

Found 41 hits Enz. Inhib. hit(s) with Target = 'Transmembrane protease serine 4' AND taxid = 9606   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Transmembrane protease serine 4


(Homo sapiens)
BDBM50430172
PNG
(CHEMBL2338685)
Show SMILES Oc1ccc(Cl)cc1C(=O)Nc1cc(c(Br)c(c1)C(F)(F)F)C(F)(F)F
Show InChI InChI=1S/C15H7BrClF6NO2/c16-12-9(14(18,19)20)4-7(5-10(12)15(21,22)23)24-13(26)8-3-6(17)1-2-11(8)25/h1-5,25H,(H,24,26)
KEGG

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n/an/a 6.00E+3n/an/an/an/an/an/a



Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL


Assay Description
Inhibition of N-terminal His6-tagged recombinant TMPRSS4 (unknown origin) fused with enterokinase cleavage sequence DYKDDDGDYKDDDDK expressed in Esch...


Bioorg Med Chem Lett 23: 1748-51 (2013)

More data for this
Ligand-Target Pair
Transmembrane protease serine 4


(Homo sapiens)
BDBM50430173
PNG
(CHEMBL2313097)
Show SMILES Cc1c(cc(NC(=O)c2cc(Cl)ccc2O)cc1C(F)(F)F)C(F)(F)F
Show InChI InChI=1S/C16H10ClF6NO2/c1-7-11(15(18,19)20)5-9(6-12(7)16(21,22)23)24-14(26)10-4-8(17)2-3-13(10)25/h2-6,25H,1H3,(H,24,26)
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n/an/a 1.00E+4n/an/an/an/an/an/a



Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL


Assay Description
Inhibition of N-terminal His6-tagged recombinant TMPRSS4 (unknown origin) fused with enterokinase cleavage sequence DYKDDDGDYKDDDDK expressed in Esch...


Bioorg Med Chem Lett 23: 1748-51 (2013)

More data for this
Ligand-Target Pair
Transmembrane protease serine 4


(Homo sapiens)
BDBM50430160
PNG
(CHEMBL536151 | TCMDC-125465)
Show SMILES Oc1ccc(Cl)cc1C(=O)Nc1cc(cc(c1)C(F)(F)F)C(F)(F)F
Show InChI InChI=1S/C15H8ClF6NO2/c16-9-1-2-12(24)11(6-9)13(25)23-10-4-7(14(17,18)19)3-8(5-10)15(20,21)22/h1-6,24H,(H,23,25)
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n/an/a 1.10E+4n/an/an/an/an/an/a



Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL


Assay Description
Inhibition of N-terminal His6-tagged recombinant TMPRSS4 (unknown origin) fused with enterokinase cleavage sequence DYKDDDGDYKDDDDK expressed in Esch...


Bioorg Med Chem Lett 23: 1748-51 (2013)

More data for this
Ligand-Target Pair
Transmembrane protease serine 4


(Homo sapiens)
BDBM50430192
PNG
(CHEMBL2313122)
Show SMILES Oc1ccc(cc1C(=O)Nc1cc(cc(c1)C(F)(F)F)C(F)(F)F)[N+]([O-])=O
Show InChI InChI=1S/C15H8F6N2O4/c16-14(17,18)7-3-8(15(19,20)21)5-9(4-7)22-13(25)11-6-10(23(26)27)1-2-12(11)24/h1-6,24H,(H,22,25)
KEGG

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n/an/a 1.20E+4n/an/an/an/an/an/a



Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL


Assay Description
Inhibition of N-terminal His6-tagged recombinant TMPRSS4 (unknown origin) fused with enterokinase cleavage sequence DYKDDDGDYKDDDDK expressed in Esch...


Bioorg Med Chem Lett 23: 1748-51 (2013)

More data for this
Ligand-Target Pair
Transmembrane protease serine 4


(Homo sapiens)
BDBM50430156
PNG
(CHEMBL2338695)
Show SMILES Oc1c(Cl)cccc1C(=O)Nc1cc(cc(c1)C(F)(F)F)C(F)(F)F
Show InChI InChI=1S/C15H8ClF6NO2/c16-11-3-1-2-10(12(11)24)13(25)23-9-5-7(14(17,18)19)4-8(6-9)15(20,21)22/h1-6,24H,(H,23,25)
KEGG

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n/an/a 1.20E+4n/an/an/an/an/an/a



Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL


Assay Description
Inhibition of N-terminal His6-tagged recombinant TMPRSS4 (unknown origin) fused with enterokinase cleavage sequence DYKDDDGDYKDDDDK expressed in Esch...


Bioorg Med Chem Lett 23: 1748-51 (2013)

More data for this
Ligand-Target Pair
Transmembrane protease serine 4


(Homo sapiens)
BDBM50430195
PNG
(CHEMBL2338696)
Show SMILES Oc1cc(Cl)ccc1C(=O)Nc1cc(cc(c1)C(F)(F)F)C(F)(F)F
Show InChI InChI=1S/C15H8ClF6NO2/c16-9-1-2-11(12(24)6-9)13(25)23-10-4-7(14(17,18)19)3-8(5-10)15(20,21)22/h1-6,24H,(H,23,25)
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n/an/a 1.20E+4n/an/an/an/an/an/a



Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL


Assay Description
Inhibition of N-terminal His6-tagged recombinant TMPRSS4 (unknown origin) fused with enterokinase cleavage sequence DYKDDDGDYKDDDDK expressed in Esch...


Bioorg Med Chem Lett 23: 1748-51 (2013)

More data for this
Ligand-Target Pair
Transmembrane protease serine 4


(Homo sapiens)
BDBM50430174
PNG
(CHEMBL2338684)
Show SMILES COc1c(cc(NC(=O)c2cc(Cl)ccc2O)cc1C(F)(F)F)C(F)(F)F
Show InChI InChI=1S/C16H10ClF6NO3/c1-27-13-10(15(18,19)20)5-8(6-11(13)16(21,22)23)24-14(26)9-4-7(17)2-3-12(9)25/h2-6,25H,1H3,(H,24,26)
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n/an/a 1.20E+4n/an/an/an/an/an/a



Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL


Assay Description
Inhibition of N-terminal His6-tagged recombinant TMPRSS4 (unknown origin) fused with enterokinase cleavage sequence DYKDDDGDYKDDDDK expressed in Esch...


Bioorg Med Chem Lett 23: 1748-51 (2013)

More data for this
Ligand-Target Pair
Transmembrane protease serine 4


(Homo sapiens)
BDBM50430183
PNG
(CHEMBL2338683)
Show SMILES Oc1ccc(Cl)cc1C(=O)Nc1cc(Br)cc(c1)C(F)(F)F
Show InChI InChI=1S/C14H8BrClF3NO2/c15-8-3-7(14(17,18)19)4-10(5-8)20-13(22)11-6-9(16)1-2-12(11)21/h1-6,21H,(H,20,22)
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n/an/a 1.20E+4n/an/an/an/an/an/a



Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL


Assay Description
Inhibition of N-terminal His6-tagged recombinant TMPRSS4 (unknown origin) fused with enterokinase cleavage sequence DYKDDDGDYKDDDDK expressed in Esch...


Bioorg Med Chem Lett 23: 1748-51 (2013)

More data for this
Ligand-Target Pair
Transmembrane protease serine 4


(Homo sapiens)
BDBM50430181
PNG
(CHEMBL2313136)
Show SMILES Oc1ccc(Cl)cc1C(=O)Nc1ccc(c(c1)C(F)(F)F)C(F)(F)F
Show InChI InChI=1S/C15H8ClF6NO2/c16-7-1-4-12(24)9(5-7)13(25)23-8-2-3-10(14(17,18)19)11(6-8)15(20,21)22/h1-6,24H,(H,23,25)
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n/an/a 1.30E+4n/an/an/an/an/an/a



Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL


Assay Description
Inhibition of N-terminal His6-tagged recombinant TMPRSS4 (unknown origin) fused with enterokinase cleavage sequence DYKDDDGDYKDDDDK expressed in Esch...


Bioorg Med Chem Lett 23: 1748-51 (2013)

More data for this
Ligand-Target Pair
Transmembrane protease serine 4


(Homo sapiens)
BDBM50430158
PNG
(CHEMBL2313117)
Show SMILES Oc1ccc(Br)cc1C(=O)Nc1cc(cc(c1)C(F)(F)F)C(F)(F)F
Show InChI InChI=1S/C15H8BrF6NO2/c16-9-1-2-12(24)11(6-9)13(25)23-10-4-7(14(17,18)19)3-8(5-10)15(20,21)22/h1-6,24H,(H,23,25)
KEGG

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n/an/a 1.30E+4n/an/an/an/an/an/a



Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL


Assay Description
Inhibition of N-terminal His6-tagged recombinant TMPRSS4 (unknown origin) fused with enterokinase cleavage sequence DYKDDDGDYKDDDDK expressed in Esch...


Bioorg Med Chem Lett 23: 1748-51 (2013)

More data for this
Ligand-Target Pair
Transmembrane protease serine 4


(Homo sapiens)
BDBM50430176
PNG
(CHEMBL589733 | MMV665807 | SJ000010289)
Show SMILES Oc1ccc(Cl)cc1C(=O)Nc1cccc(c1)C(F)(F)F
Show InChI InChI=1S/C14H9ClF3NO2/c15-9-4-5-12(20)11(7-9)13(21)19-10-3-1-2-8(6-10)14(16,17)18/h1-7,20H,(H,19,21)
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n/an/a 1.30E+4n/an/an/an/an/an/a



Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL


Assay Description
Inhibition of N-terminal His6-tagged recombinant TMPRSS4 (unknown origin) fused with enterokinase cleavage sequence DYKDDDGDYKDDDDK expressed in Esch...


Bioorg Med Chem Lett 23: 1748-51 (2013)

More data for this
Ligand-Target Pair
Transmembrane protease serine 4


(Homo sapiens)
BDBM50430184
PNG
(CHEMBL2313095)
Show SMILES COc1cc(NC(=O)c2cc(Cl)ccc2O)cc(c1)C(F)(F)F
Show InChI InChI=1S/C15H11ClF3NO3/c1-23-11-5-8(15(17,18)19)4-10(7-11)20-14(22)12-6-9(16)2-3-13(12)21/h2-7,21H,1H3,(H,20,22)
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n/an/a 1.60E+4n/an/an/an/an/an/a



Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL


Assay Description
Inhibition of N-terminal His6-tagged recombinant TMPRSS4 (unknown origin) fused with enterokinase cleavage sequence DYKDDDGDYKDDDDK expressed in Esch...


Bioorg Med Chem Lett 23: 1748-51 (2013)

More data for this
Ligand-Target Pair
Transmembrane protease serine 4


(Homo sapiens)
BDBM50430177
PNG
(CHEMBL2088014)
Show SMILES Oc1ccc(Cl)cc1C(=O)Nc1ccc(cc1)C(F)(F)F
Show InChI InChI=1S/C14H9ClF3NO2/c15-9-3-6-12(20)11(7-9)13(21)19-10-4-1-8(2-5-10)14(16,17)18/h1-7,20H,(H,19,21)
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n/an/a 1.60E+4n/an/an/an/an/an/a



Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL


Assay Description
Inhibition of N-terminal His6-tagged recombinant TMPRSS4 (unknown origin) fused with enterokinase cleavage sequence DYKDDDGDYKDDDDK expressed in Esch...


Bioorg Med Chem Lett 23: 1748-51 (2013)

More data for this
Ligand-Target Pair
Transmembrane protease serine 4


(Homo sapiens)
BDBM50430161
PNG
(CHEMBL2313134)
Show SMILES Oc1ccc(Cl)cc1C(=O)NCc1cc(cc(c1)C(F)(F)F)C(F)(F)F
Show InChI InChI=1S/C16H10ClF6NO2/c17-11-1-2-13(25)12(6-11)14(26)24-7-8-3-9(15(18,19)20)5-10(4-8)16(21,22)23/h1-6,25H,7H2,(H,24,26)
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n/an/a 1.80E+4n/an/an/an/an/an/a



Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL


Assay Description
Inhibition of N-terminal His6-tagged recombinant TMPRSS4 (unknown origin) fused with enterokinase cleavage sequence DYKDDDGDYKDDDDK expressed in Esch...


Bioorg Med Chem Lett 23: 1748-51 (2013)

More data for this
Ligand-Target Pair
Transmembrane protease serine 4


(Homo sapiens)
BDBM50430185
PNG
(CHEMBL2179173)
Show SMILES Oc1ccc(Cl)cc1C(=O)Nc1cc(Cl)cc(Cl)c1
Show InChI InChI=1S/C13H8Cl3NO2/c14-7-1-2-12(18)11(6-7)13(19)17-10-4-8(15)3-9(16)5-10/h1-6,18H,(H,17,19)
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n/an/a 1.90E+4n/an/an/an/an/an/a



Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL


Assay Description
Inhibition of N-terminal His6-tagged recombinant TMPRSS4 (unknown origin) fused with enterokinase cleavage sequence DYKDDDGDYKDDDDK expressed in Esch...


Bioorg Med Chem Lett 23: 1748-51 (2013)

More data for this
Ligand-Target Pair
Transmembrane protease serine 4


(Homo sapiens)
BDBM50430191
PNG
(CHEMBL2338697)
Show SMILES Oc1ccc(cc1C(=O)Nc1cc(cc(c1)C(F)(F)F)C(F)(F)F)C#N
Show InChI InChI=1S/C16H8F6N2O2/c17-15(18,19)9-4-10(16(20,21)22)6-11(5-9)24-14(26)12-3-8(7-23)1-2-13(12)25/h1-6,25H,(H,24,26)
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n/an/a 1.90E+4n/an/an/an/an/an/a



Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL


Assay Description
Inhibition of N-terminal His6-tagged recombinant TMPRSS4 (unknown origin) fused with enterokinase cleavage sequence DYKDDDGDYKDDDDK expressed in Esch...


Bioorg Med Chem Lett 23: 1748-51 (2013)

More data for this
Ligand-Target Pair
Transmembrane protease serine 4


(Homo sapiens)
BDBM50430182
PNG
(CHEMBL2313138)
Show SMILES Oc1ccc(Cl)cc1C(=O)Nc1cc(ccc1C(F)(F)F)C(F)(F)F
Show InChI InChI=1S/C15H8ClF6NO2/c16-8-2-4-12(24)9(6-8)13(25)23-11-5-7(14(17,18)19)1-3-10(11)15(20,21)22/h1-6,24H,(H,23,25)
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n/an/a 2.00E+4n/an/an/an/an/an/a



Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL


Assay Description
Inhibition of N-terminal His6-tagged recombinant TMPRSS4 (unknown origin) fused with enterokinase cleavage sequence DYKDDDGDYKDDDDK expressed in Esch...


Bioorg Med Chem Lett 23: 1748-51 (2013)

More data for this
Ligand-Target Pair
Transmembrane protease serine 4


(Homo sapiens)
BDBM50430194
PNG
(CHEMBL2313115)
Show SMILES Cc1ccc(O)c(c1)C(=O)Nc1cc(cc(c1)C(F)(F)F)C(F)(F)F
Show InChI InChI=1S/C16H11F6NO2/c1-8-2-3-13(24)12(4-8)14(25)23-11-6-9(15(17,18)19)5-10(7-11)16(20,21)22/h2-7,24H,1H3,(H,23,25)
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n/an/a 2.80E+4n/an/an/an/an/an/a



Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL


Assay Description
Inhibition of N-terminal His6-tagged recombinant TMPRSS4 (unknown origin) fused with enterokinase cleavage sequence DYKDDDGDYKDDDDK expressed in Esch...


Bioorg Med Chem Lett 23: 1748-51 (2013)

More data for this
Ligand-Target Pair
Transmembrane protease serine 4


(Homo sapiens)
BDBM50430178
PNG
(CHEMBL2313080)
Show SMILES Oc1ccc(Cl)cc1C(=O)Nc1cc(ccc1F)C(F)(F)F
Show InChI InChI=1S/C14H8ClF4NO2/c15-8-2-4-12(21)9(6-8)13(22)20-11-5-7(14(17,18)19)1-3-10(11)16/h1-6,21H,(H,20,22)
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n/an/a 2.80E+4n/an/an/an/an/an/a



Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL


Assay Description
Inhibition of N-terminal His6-tagged recombinant TMPRSS4 (unknown origin) fused with enterokinase cleavage sequence DYKDDDGDYKDDDDK expressed in Esch...


Bioorg Med Chem Lett 23: 1748-51 (2013)

More data for this
Ligand-Target Pair
Transmembrane protease serine 4


(Homo sapiens)
BDBM50430157
PNG
(CHEMBL2313116)
Show SMILES Oc1ccc(F)cc1C(=O)Nc1cc(cc(c1)C(F)(F)F)C(F)(F)F
Show InChI InChI=1S/C15H8F7NO2/c16-9-1-2-12(24)11(6-9)13(25)23-10-4-7(14(17,18)19)3-8(5-10)15(20,21)22/h1-6,24H,(H,23,25)
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n/an/a 2.90E+4n/an/an/an/an/an/a



Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL


Assay Description
Inhibition of N-terminal His6-tagged recombinant TMPRSS4 (unknown origin) fused with enterokinase cleavage sequence DYKDDDGDYKDDDDK expressed in Esch...


Bioorg Med Chem Lett 23: 1748-51 (2013)

More data for this
Ligand-Target Pair
Transmembrane protease serine 4


(Homo sapiens)
BDBM50430193
PNG
(CHEMBL2313119)
Show SMILES COc1ccc(O)c(c1)C(=O)Nc1cc(cc(c1)C(F)(F)F)C(F)(F)F
Show InChI InChI=1S/C16H11F6NO3/c1-26-11-2-3-13(24)12(7-11)14(25)23-10-5-8(15(17,18)19)4-9(6-10)16(20,21)22/h2-7,24H,1H3,(H,23,25)
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n/an/a 2.90E+4n/an/an/an/an/an/a



Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL


Assay Description
Inhibition of N-terminal His6-tagged recombinant TMPRSS4 (unknown origin) fused with enterokinase cleavage sequence DYKDDDGDYKDDDDK expressed in Esch...


Bioorg Med Chem Lett 23: 1748-51 (2013)

More data for this
Ligand-Target Pair
Transmembrane protease serine 4


(Homo sapiens)
BDBM50430180
PNG
(CHEMBL2313089)
Show SMILES Oc1ccc(Cl)cc1C(=O)Nc1ccc(Br)c(c1)C(F)(F)F
Show InChI InChI=1S/C14H8BrClF3NO2/c15-11-3-2-8(6-10(11)14(17,18)19)20-13(22)9-5-7(16)1-4-12(9)21/h1-6,21H,(H,20,22)
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n/an/a 3.00E+4n/an/an/an/an/an/a



Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL


Assay Description
Inhibition of N-terminal His6-tagged recombinant TMPRSS4 (unknown origin) fused with enterokinase cleavage sequence DYKDDDGDYKDDDDK expressed in Esch...


Bioorg Med Chem Lett 23: 1748-51 (2013)

More data for this
Ligand-Target Pair
Transmembrane protease serine 4


(Homo sapiens)
BDBM50430179
PNG
(CHEMBL2313088)
Show SMILES Oc1ccc(Cl)cc1C(=O)Nc1ccc(Cl)c(c1)C(F)(F)F
Show InChI InChI=1S/C14H8Cl2F3NO2/c15-7-1-4-12(21)9(5-7)13(22)20-8-2-3-11(16)10(6-8)14(17,18)19/h1-6,21H,(H,20,22)
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n/an/a 3.50E+4n/an/an/an/an/an/a



Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL


Assay Description
Inhibition of N-terminal His6-tagged recombinant TMPRSS4 (unknown origin) fused with enterokinase cleavage sequence DYKDDDGDYKDDDDK expressed in Esch...


Bioorg Med Chem Lett 23: 1748-51 (2013)

More data for this
Ligand-Target Pair
Transmembrane protease serine 4


(Homo sapiens)
BDBM50430186
PNG
(CHEMBL2178702)
Show SMILES Cc1cc(C)cc(NC(=O)c2cc(Cl)ccc2O)c1
Show InChI InChI=1S/C15H14ClNO2/c1-9-5-10(2)7-12(6-9)17-15(19)13-8-11(16)3-4-14(13)18/h3-8,18H,1-2H3,(H,17,19)
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n/an/a 3.90E+4n/an/an/an/an/an/a



Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL


Assay Description
Inhibition of N-terminal His6-tagged recombinant TMPRSS4 (unknown origin) fused with enterokinase cleavage sequence DYKDDDGDYKDDDDK expressed in Esch...


Bioorg Med Chem Lett 23: 1748-51 (2013)

More data for this
Ligand-Target Pair
Transmembrane protease serine 4


(Homo sapiens)
BDBM50398077
PNG
(CHEMBL1256178)
Show SMILES NCCc1ccc(cc1)S(F)(=O)=O
Show InChI InChI=1S/C8H10FNO2S/c9-13(11,12)8-3-1-7(2-4-8)5-6-10/h1-4H,5-6,10H2
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n/an/a 3.90E+4n/an/an/an/an/an/a



Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL


Assay Description
Inhibition of N-terminal His6-tagged recombinant TMPRSS4 (unknown origin) fused with enterokinase cleavage sequence DYKDDDGDYKDDDDK expressed in Esch...


Bioorg Med Chem Lett 23: 1748-51 (2013)

More data for this
Ligand-Target Pair
Transmembrane protease serine 4


(Homo sapiens)
BDBM50430187
PNG
(CHEMBL1892375)
Show SMILES Oc1ccc(Cl)cc1C(=O)Nc1ccccc1
Show InChI InChI=1S/C13H10ClNO2/c14-9-6-7-12(16)11(8-9)13(17)15-10-4-2-1-3-5-10/h1-8,16H,(H,15,17)
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n/an/a 5.00E+4n/an/an/an/an/an/a



Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL


Assay Description
Inhibition of N-terminal His6-tagged recombinant TMPRSS4 (unknown origin) fused with enterokinase cleavage sequence DYKDDDGDYKDDDDK expressed in Esch...


Bioorg Med Chem Lett 23: 1748-51 (2013)

More data for this
Ligand-Target Pair
Transmembrane protease serine 4


(Homo sapiens)
BDBM50430175
PNG
(CHEMBL584646 | GNF-Pf-1115)
Show SMILES Oc1ccc(Cl)cc1C(=O)Nc1ccc(cc1)C#N
Show InChI InChI=1S/C14H9ClN2O2/c15-10-3-6-13(18)12(7-10)14(19)17-11-4-1-9(8-16)2-5-11/h1-7,18H,(H,17,19)
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n/an/a 7.60E+4n/an/an/an/an/an/a



Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL


Assay Description
Inhibition of N-terminal His6-tagged recombinant TMPRSS4 (unknown origin) fused with enterokinase cleavage sequence DYKDDDGDYKDDDDK expressed in Esch...


Bioorg Med Chem Lett 23: 1748-51 (2013)

More data for this
Ligand-Target Pair
Transmembrane protease serine 4


(Homo sapiens)
BDBM50430167
PNG
(CHEMBL2338689)
Show SMILES Oc1ccc(Cl)cc1C(=O)Nc1ccc(cn1)C#N
Show InChI InChI=1S/C13H8ClN3O2/c14-9-2-3-11(18)10(5-9)13(19)17-12-4-1-8(6-15)7-16-12/h1-5,7,18H,(H,16,17,19)
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n/an/a 8.00E+4n/an/an/an/an/an/a



Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL


Assay Description
Inhibition of N-terminal His6-tagged recombinant TMPRSS4 (unknown origin) fused with enterokinase cleavage sequence DYKDDDGDYKDDDDK expressed in Esch...


Bioorg Med Chem Lett 23: 1748-51 (2013)

More data for this
Ligand-Target Pair
Transmembrane protease serine 4


(Homo sapiens)
BDBM50430162
PNG
(CHEMBL2338694)
Show SMILES Oc1ccc(Cl)cc1C(=O)Nc1cnc2ccccc2c1
Show InChI InChI=1S/C16H11ClN2O2/c17-11-5-6-15(20)13(8-11)16(21)19-12-7-10-3-1-2-4-14(10)18-9-12/h1-9,20H,(H,19,21)
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n/an/a 8.50E+4n/an/an/an/an/an/a



Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL


Assay Description
Inhibition of N-terminal His6-tagged recombinant TMPRSS4 (unknown origin) fused with enterokinase cleavage sequence DYKDDDGDYKDDDDK expressed in Esch...


Bioorg Med Chem Lett 23: 1748-51 (2013)

More data for this
Ligand-Target Pair
Transmembrane protease serine 4


(Homo sapiens)
BDBM50430170
PNG
(CHEMBL2338686)
Show SMILES Oc1c(ccc2ccccc12)C(=O)Nc1cc(cc(c1)C(F)(F)F)C(F)(F)F
Show InChI InChI=1S/C19H11F6NO2/c20-18(21,22)11-7-12(19(23,24)25)9-13(8-11)26-17(28)15-6-5-10-3-1-2-4-14(10)16(15)27/h1-9,27H,(H,26,28)
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n/an/a>1.00E+5n/an/an/an/an/an/a



Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL


Assay Description
Inhibition of N-terminal His6-tagged recombinant TMPRSS4 (unknown origin) fused with enterokinase cleavage sequence DYKDDDGDYKDDDDK expressed in Esch...


Bioorg Med Chem Lett 23: 1748-51 (2013)

More data for this
Ligand-Target Pair
Transmembrane protease serine 4


(Homo sapiens)
BDBM50430159
PNG
(CHEMBL461542)
Show SMILES Oc1ccccc1C(=O)Nc1cc(cc(c1)C(F)(F)F)C(F)(F)F
Show InChI InChI=1S/C15H9F6NO2/c16-14(17,18)8-5-9(15(19,20)21)7-10(6-8)22-13(24)11-3-1-2-4-12(11)23/h1-7,23H,(H,22,24)
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n/an/a>1.00E+5n/an/an/an/an/an/a



Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL


Assay Description
Inhibition of N-terminal His6-tagged recombinant TMPRSS4 (unknown origin) fused with enterokinase cleavage sequence DYKDDDGDYKDDDDK expressed in Esch...


Bioorg Med Chem Lett 23: 1748-51 (2013)

More data for this
Ligand-Target Pair
Transmembrane protease serine 4


(Homo sapiens)
BDBM50430190
PNG
(CHEMBL2338698)
Show SMILES NC(=O)c1ccc(O)c(c1)C(=O)Nc1cc(cc(c1)C(F)(F)F)C(F)(F)F
Show InChI InChI=1S/C16H10F6N2O3/c17-15(18,19)8-4-9(16(20,21)22)6-10(5-8)24-14(27)11-3-7(13(23)26)1-2-12(11)25/h1-6,25H,(H2,23,26)(H,24,27)
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n/an/a>1.00E+5n/an/an/an/an/an/a



Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL


Assay Description
Inhibition of N-terminal His6-tagged recombinant TMPRSS4 (unknown origin) fused with enterokinase cleavage sequence DYKDDDGDYKDDDDK expressed in Esch...


Bioorg Med Chem Lett 23: 1748-51 (2013)

More data for this
Ligand-Target Pair
Transmembrane protease serine 4


(Homo sapiens)
BDBM50430189
PNG
(CHEMBL2313123)
Show SMILES CC(=O)Oc1ccc(Cl)cc1C(=O)Nc1cc(cc(c1)C(F)(F)F)C(F)(F)F
Show InChI InChI=1S/C17H10ClF6NO3/c1-8(26)28-14-3-2-11(18)7-13(14)15(27)25-12-5-9(16(19,20)21)4-10(6-12)17(22,23)24/h2-7H,1H3,(H,25,27)
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n/an/a>1.00E+5n/an/an/an/an/an/a



Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL


Assay Description
Inhibition of N-terminal His6-tagged recombinant TMPRSS4 (unknown origin) fused with enterokinase cleavage sequence DYKDDDGDYKDDDDK expressed in Esch...


Bioorg Med Chem Lett 23: 1748-51 (2013)

More data for this
Ligand-Target Pair
Transmembrane protease serine 4


(Homo sapiens)
BDBM50430188
PNG
(CHEMBL2313125)
Show SMILES FC(F)(F)c1cc(NC(=O)c2cc(Cl)ccc2OCc2ccccc2)cc(c1)C(F)(F)F
Show InChI InChI=1S/C22H14ClF6NO2/c23-16-6-7-19(32-12-13-4-2-1-3-5-13)18(11-16)20(31)30-17-9-14(21(24,25)26)8-15(10-17)22(27,28)29/h1-11H,12H2,(H,30,31)
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n/an/a>1.00E+5n/an/an/an/an/an/a



Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL


Assay Description
Inhibition of N-terminal His6-tagged recombinant TMPRSS4 (unknown origin) fused with enterokinase cleavage sequence DYKDDDGDYKDDDDK expressed in Esch...


Bioorg Med Chem Lett 23: 1748-51 (2013)

More data for this
Ligand-Target Pair
Transmembrane protease serine 4


(Homo sapiens)
BDBM50430163
PNG
(CHEMBL2338693)
Show SMILES Oc1ccc(Cl)cc1C(=O)Nc1ncccn1
Show InChI InChI=1S/C11H8ClN3O2/c12-7-2-3-9(16)8(6-7)10(17)15-11-13-4-1-5-14-11/h1-6,16H,(H,13,14,15,17)
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n/an/a>1.00E+5n/an/an/an/an/an/a



Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL


Assay Description
Inhibition of N-terminal His6-tagged recombinant TMPRSS4 (unknown origin) fused with enterokinase cleavage sequence DYKDDDGDYKDDDDK expressed in Esch...


Bioorg Med Chem Lett 23: 1748-51 (2013)

More data for this
Ligand-Target Pair
Transmembrane protease serine 4


(Homo sapiens)
BDBM50430164
PNG
(CHEMBL2338692)
Show SMILES Oc1ccc(Cl)cc1C(=O)Nc1ccnc(Cl)c1
Show InChI InChI=1S/C12H8Cl2N2O2/c13-7-1-2-10(17)9(5-7)12(18)16-8-3-4-15-11(14)6-8/h1-6,17H,(H,15,16,18)
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n/an/a>1.00E+5n/an/an/an/an/an/a



Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL


Assay Description
Inhibition of N-terminal His6-tagged recombinant TMPRSS4 (unknown origin) fused with enterokinase cleavage sequence DYKDDDGDYKDDDDK expressed in Esch...


Bioorg Med Chem Lett 23: 1748-51 (2013)

More data for this
Ligand-Target Pair
Transmembrane protease serine 4


(Homo sapiens)
BDBM50430165
PNG
(CHEMBL2338691)
Show SMILES Oc1ccc(Cl)cc1C(=O)Nc1ccc(Cl)nc1
Show InChI InChI=1S/C12H8Cl2N2O2/c13-7-1-3-10(17)9(5-7)12(18)16-8-2-4-11(14)15-6-8/h1-6,17H,(H,16,18)
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n/an/a>1.00E+5n/an/an/an/an/an/a



Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL


Assay Description
Inhibition of N-terminal His6-tagged recombinant TMPRSS4 (unknown origin) fused with enterokinase cleavage sequence DYKDDDGDYKDDDDK expressed in Esch...


Bioorg Med Chem Lett 23: 1748-51 (2013)

More data for this
Ligand-Target Pair
Transmembrane protease serine 4


(Homo sapiens)
BDBM50430166
PNG
(CHEMBL2338690)
Show SMILES Oc1ccc(Cl)cc1C(=O)Nc1ccc(cn1)C(F)(F)F
Show InChI InChI=1S/C13H8ClF3N2O2/c14-8-2-3-10(20)9(5-8)12(21)19-11-4-1-7(6-18-11)13(15,16)17/h1-6,20H,(H,18,19,21)
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n/an/a>1.00E+5n/an/an/an/an/an/a



Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL


Assay Description
Inhibition of N-terminal His6-tagged recombinant TMPRSS4 (unknown origin) fused with enterokinase cleavage sequence DYKDDDGDYKDDDDK expressed in Esch...


Bioorg Med Chem Lett 23: 1748-51 (2013)

More data for this
Ligand-Target Pair
Transmembrane protease serine 4


(Homo sapiens)
BDBM50430168
PNG
(CHEMBL2338688)
Show SMILES Oc1c(cnc2ccccc12)C(=O)Nc1cc(cc(c1)C(F)(F)F)C(F)(F)F
Show InChI InChI=1S/C18H10F6N2O2/c19-17(20,21)9-5-10(18(22,23)24)7-11(6-9)26-16(28)13-8-25-14-4-2-1-3-12(14)15(13)27/h1-8H,(H,25,27)(H,26,28)
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n/an/a>1.00E+5n/an/an/an/an/an/a



Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL


Assay Description
Inhibition of N-terminal His6-tagged recombinant TMPRSS4 (unknown origin) fused with enterokinase cleavage sequence DYKDDDGDYKDDDDK expressed in Esch...


Bioorg Med Chem Lett 23: 1748-51 (2013)

More data for this
Ligand-Target Pair
Transmembrane protease serine 4


(Homo sapiens)
BDBM50430171
PNG
(CHEMBL2313101)
Show SMILES Oc1ccc(Cl)cc1C(=O)Nc1cc(Cl)c(Cl)c(Cl)c1
Show InChI InChI=1S/C13H7Cl4NO2/c14-6-1-2-11(19)8(3-6)13(20)18-7-4-9(15)12(17)10(16)5-7/h1-5,19H,(H,18,20)
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n/an/a>1.00E+5n/an/an/an/an/an/a



Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL


Assay Description
Inhibition of N-terminal His6-tagged recombinant TMPRSS4 (unknown origin) fused with enterokinase cleavage sequence DYKDDDGDYKDDDDK expressed in Esch...


Bioorg Med Chem Lett 23: 1748-51 (2013)

More data for this
Ligand-Target Pair
Transmembrane protease serine 4


(Homo sapiens)
BDBM50430169
PNG
(CHEMBL2338687)
Show SMILES FC(F)(F)c1cc(NC(=O)c2cc(Cl)c[nH]c2=O)cc(c1)C(F)(F)F
Show InChI InChI=1S/C14H7ClF6N2O2/c15-8-4-10(11(24)22-5-8)12(25)23-9-2-6(13(16,17)18)1-7(3-9)14(19,20)21/h1-5H,(H,22,24)(H,23,25)
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n/an/a>1.00E+5n/an/an/an/an/an/a



Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL


Assay Description
Inhibition of N-terminal His6-tagged recombinant TMPRSS4 (unknown origin) fused with enterokinase cleavage sequence DYKDDDGDYKDDDDK expressed in Esch...


Bioorg Med Chem Lett 23: 1748-51 (2013)

More data for this
Ligand-Target Pair