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Found 12 hits Enz. Inhib. hit(s) with Target = 'Triosephosphate isomerase' AND taxid = 9606   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Triosephosphate isomerase


(Homo sapiens)
BDBM50167777
PNG
(2-(hydroxyamino)-2-oxoethyl dihydrogen phosphate |...)
Show SMILES ONC(=O)COP(O)(O)=O
Show InChI InChI=1S/C2H6NO6P/c4-2(3-5)1-9-10(6,7)8/h5H,1H2,(H,3,4)(H2,6,7,8)
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PubMed
3.00E+3n/an/an/an/an/an/an/an/a



UMR 8182

Curated by ChEMBL


Assay Description
Inhibition of triosephosphate isomerase


Citation and Details
More data for this
Ligand-Target Pair
Triosephosphate isomerase


(Homo sapiens)
BDBM50167777
PNG
(2-(hydroxyamino)-2-oxoethyl dihydrogen phosphate |...)
Show SMILES ONC(=O)COP(O)(O)=O
Show InChI InChI=1S/C2H6NO6P/c4-2(3-5)1-9-10(6,7)8/h5H,1H2,(H,3,4)(H2,6,7,8)
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4.00E+3n/an/an/an/an/an/an/an/a



University of Michigan

Curated by ChEMBL


Assay Description
Inhibition of Triosephosphate isomerase


Citation and Details
More data for this
Ligand-Target Pair
Triosephosphate isomerase


(Homo sapiens)
BDBM50167775
PNG
((Z)-2-amino-2-(hydroxyimino)ethyl hydrogen phospha...)
Show SMILES ONC(=N)COP(O)(O)=O
Show InChI InChI=1S/C2H7N2O5P/c3-2(4-5)1-9-10(6,7)8/h5H,1H2,(H2,3,4)(H2,6,7,8)
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4.50E+3n/an/an/an/an/an/an/an/a



UMR 8182

Curated by ChEMBL


Assay Description
Inhibition of triosephosphate isomerase


Citation and Details
More data for this
Ligand-Target Pair
Triosephosphate isomerase


(Homo sapiens)
BDBM50113828
PNG
(CHEMBL311322 | {1-[1-(1-Cyclohexylmethyl-2-hydroxy...)
Show SMILES CNC(=O)[C@H](CC(C)C)C[C@H](O)[C@H](CC1CCCCC1)NC(=O)C(Cc1cnc[nH]1)NC(=O)C(Cc1ccccc1)NC(=O)OC(C)(C)C
Show InChI InChI=1S/C37H58N6O6/c1-24(2)17-27(33(45)38-6)20-32(44)29(18-25-13-9-7-10-14-25)41-35(47)31(21-28-22-39-23-40-28)42-34(46)30(19-26-15-11-8-12-16-26)43-36(48)49-37(3,4)5/h8,11-12,15-16,22-25,27,29-32,44H,7,9-10,13-14,17-21H2,1-6H3,(H,38,45)(H,39,40)(H,41,47)(H,42,46)(H,43,48)/t27-,29+,30?,31?,32+/m1/s1
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1.50E+4n/an/an/an/an/an/an/an/a



University of Parma

Curated by ChEMBL


Assay Description
Binding affinity against Triosephosphate isomerase


J Med Chem 45: 2469-83 (2002)

More data for this
Ligand-Target Pair
Triosephosphate isomerase


(Homo sapiens)
BDBM50167772
PNG
(2-hydrazinyl-2-oxoethyl hydrogen phosphate | CHEMB...)
Show SMILES NNC(=O)COP(O)(O)=O
Show InChI InChI=1S/C2H7N2O5P/c3-4-2(5)1-9-10(6,7)8/h1,3H2,(H,4,5)(H2,6,7,8)
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1.11E+5n/an/an/an/an/an/an/an/a



UMR 8182

Curated by ChEMBL


Assay Description
Inhibition of triosephosphate isomerase


Citation and Details
More data for this
Ligand-Target Pair
Triosephosphate isomerase


(Homo sapiens)
BDBM50167776
PNG
((2-Hydroxycarbamoyl-ethyl)-phosphonic acid | 3-(hy...)
Show SMILES ONC(=O)CCP(O)(O)=O
Show InChI InChI=1S/C3H8NO5P/c5-3(4-6)1-2-10(7,8)9/h6H,1-2H2,(H,4,5)(H2,7,8,9)
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1.60E+5n/an/an/an/an/an/an/an/a



UMR 8182

Curated by ChEMBL


Assay Description
Inhibition of triosephosphate isomerase


Citation and Details
More data for this
Ligand-Target Pair
Triosephosphate isomerase


(Homo sapiens)
BDBM50198029
PNG
(CHEMBL390655 | hydrogen [1-azaniumyl-2-(hydroxycar...)
Show SMILES [NH3+]C(CC(=O)NO)P(O)([O-])=O
Show InChI InChI=1S/C3H9N2O5P/c4-2(11(8,9)10)1-3(6)5-7/h2,7H,1,4H2,(H,5,6)(H2,8,9,10)
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>5.00E+5n/an/an/an/an/an/an/an/a



UMR 8182

Curated by ChEMBL


Assay Description
Inhibition of triosephosphate isomerase


Citation and Details
More data for this
Ligand-Target Pair
Triosephosphate isomerase


(Homo sapiens)
BDBM50198028
PNG
(hydrogen 1-hydroxy-3-(hydroxyamino)-3-oxopropylpho...)
Show SMILES ONC(=O)CC(=O)P(O)(O)[O-]
Show InChI InChI=1S/C3H7NO6P/c5-2(4-7)1-3(6)11(8,9)10/h7-9,11H,1H2,(H,4,5)/q-1
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>1.00E+6n/an/an/an/an/an/an/an/a



UMR 8182

Curated by ChEMBL


Assay Description
Inhibition of triosephosphate isomerase


Citation and Details
More data for this
Ligand-Target Pair
Triosephosphate isomerase


(Homo sapiens)
BDBM50415047
PNG
(CHEMBL567076)
Show SMILES COC(=O)C1CC(=O)c2oc(=O)c3cc(O)c(O)c(O)c3c12
Show InChI InChI=1S/C14H10O8/c1-21-13(19)5-3-7(16)12-9(5)8-4(14(20)22-12)2-6(15)10(17)11(8)18/h2,5,15,17-18H,3H2,1H3
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n/an/a>1.00E+6n/an/an/an/an/an/a



Universidad Aut£noma del Estado de Hidalgo

Curated by ChEMBL


Assay Description
Inhibition of human recombinant triosephosphate isomerase after 2 hrs


Citation and Details
More data for this
Ligand-Target Pair
Triosephosphate isomerase


(Homo sapiens)
BDBM50415048
PNG
(CHEMBL567077)
Show SMILES CCOC(=O)C1CC(=O)c2oc(=O)c3cc(O)c(O)c(O)c3c12
Show InChI InChI=1S/C15H12O8/c1-2-22-14(20)6-4-8(17)13-10(6)9-5(15(21)23-13)3-7(16)11(18)12(9)19/h3,6,16,18-19H,2,4H2,1H3
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n/an/a>1.00E+6n/an/an/an/an/an/a



Universidad Aut£noma del Estado de Hidalgo

Curated by ChEMBL


Assay Description
Inhibition of human recombinant triosephosphate isomerase after 2 hrs


Citation and Details
More data for this
Ligand-Target Pair
Triosephosphate isomerase


(Homo sapiens)
BDBM50415050
PNG
(CHEMBL567497)
Show SMILES COC(=O)C1CC(=O)c2oc(=O)c3cc(O)c(OC)c(OC)c3c12
Show InChI InChI=1S/C16H14O8/c1-21-13-9(18)5-7-11(14(13)22-2)10-6(15(19)23-3)4-8(17)12(10)24-16(7)20/h5-6,18H,4H2,1-3H3
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n/an/a>1.00E+6n/an/an/an/an/an/a



Universidad Aut£noma del Estado de Hidalgo

Curated by ChEMBL


Assay Description
Inhibition of human recombinant triosephosphate isomerase after 2 hrs


Citation and Details
More data for this
Ligand-Target Pair
Triosephosphate isomerase


(Homo sapiens)
BDBM50415049
PNG
(CHEMBL568338)
Show SMILES CCCCOC(=O)C1CC(=O)c2oc(=O)c3cc(O)c(O)c(O)c3c12
Show InChI InChI=1S/C17H16O8/c1-2-3-4-24-16(22)8-6-10(19)15-12(8)11-7(17(23)25-15)5-9(18)13(20)14(11)21/h5,8,18,20-21H,2-4,6H2,1H3
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n/an/a>1.00E+6n/an/an/an/an/an/a



Universidad Aut£noma del Estado de Hidalgo

Curated by ChEMBL


Assay Description
Inhibition of human recombinant triosephosphate isomerase after 2 hrs


Citation and Details
More data for this
Ligand-Target Pair