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Found 24 hits Enz. Inhib. hit(s) with Target = 'Trp Aprorepressor' AND taxid = 83333   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Trp Aprorepressor


(Escherichia coli (strain K12))
BDBM92681
PNG
(3-Beta-Indole-acrylic acid (Tran), 1)
Show SMILES [O-]C(=O)\C=C\c1c[nH]c2ccccc12
Show InChI InChI=1S/C11H9NO2/c13-11(14)6-5-8-7-12-10-4-2-1-3-9(8)10/h1-7,12H,(H,13,14)/p-1/b6-5+
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n/an/an/a 516n/an/an/an/an/a



University of Chicago



Assay Description
Binding assay of L-trptophan and analogues to trp aporepressor


J Biol Chem 262: 4922-7 (1987)

More data for this
Ligand-Target Pair
Trp Aprorepressor


(Escherichia coli (strain K12))
BDBM92702
PNG
(L-Tyrosine, 24)
Show SMILES [NH3+]C(Cc1ccc(O)cc1)C([O-])=O
Show InChI InChI=1S/C9H11NO3/c10-8(9(12)13)5-6-1-3-7(11)4-2-6/h1-4,8,11H,5,10H2,(H,12,13)
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n/an/an/a>3.00E+6n/an/an/an/an/a



University of Chicago



Assay Description
Binding assay of L-trptophan and analogues to trp aporepressor


J Biol Chem 262: 4922-7 (1987)

More data for this
Ligand-Target Pair
Trp Aprorepressor


(Escherichia coli (strain K12))
BDBM92683
PNG
(Indole-3-butyric acid, 3)
Show SMILES [O-]C(=O)CCCc1c[nH]c2ccccc12
Show InChI InChI=1S/C12H13NO2/c14-12(15)7-3-4-9-8-13-11-6-2-1-5-10(9)11/h1-2,5-6,8,13H,3-4,7H2,(H,14,15)/p-1
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PubMed
n/an/an/a 5.51E+3n/an/an/an/an/a



University of Chicago



Assay Description
Binding assay of L-trptophan and analogues to trp aporepressor


J Biol Chem 262: 4922-7 (1987)

More data for this
Ligand-Target Pair
Trp Aprorepressor


(Escherichia coli (strain K12))
BDBM92684
PNG
(Indole-3-propionic acid, 4)
Show SMILES [O-]C(=O)CCc1c[nH]c2ccccc12
Show InChI InChI=1S/C11H11NO2/c13-11(14)6-5-8-7-12-10-4-2-1-3-9(8)10/h1-4,7,12H,5-6H2,(H,13,14)/p-1
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PubMed
n/an/an/a 9.74E+3n/an/an/an/an/a



University of Chicago



Assay Description
Binding assay of L-trptophan and analogues to trp aporepressor


J Biol Chem 262: 4922-7 (1987)

More data for this
Ligand-Target Pair
Trp Aprorepressor


(Escherichia coli (strain K12))
BDBM92685
PNG
(D-Tryptophan, 20 | L-Tryptophan, 5)
Show SMILES [NH3+]C(Cc1c[nH]c2ccccc12)C([O-])=O
Show InChI InChI=1S/C11H12N2O2/c12-9(11(14)15)5-7-6-13-10-4-2-1-3-8(7)10/h1-4,6,9,13H,5,12H2,(H,14,15)
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n/an/an/a 1.46E+4n/an/an/an/an/a



University of Chicago



Assay Description
Binding assay of L-trptophan and analogues to trp aporepressor


J Biol Chem 262: 4922-7 (1987)

More data for this
Ligand-Target Pair
Trp Aprorepressor


(Escherichia coli (strain K12))
BDBM92686
PNG
(Tryptaphol, 6)
Show SMILES OCCc1c[nH]c2ccccc12
Show InChI InChI=1S/C10H11NO/c12-6-5-8-7-11-10-4-2-1-3-9(8)10/h1-4,7,11-12H,5-6H2
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PubMed
n/an/an/a 2.33E+4n/an/an/an/an/a



University of Chicago



Assay Description
Binding assay of L-trptophan and analogues to trp aporepressor


J Biol Chem 262: 4922-7 (1987)

More data for this
Ligand-Target Pair
Trp Aprorepressor


(Escherichia coli (strain K12))
BDBM50094702
PNG
(1H-indole | CHEMBL15844 | Indol | Indole, 7 | indo...)
Show SMILES c1cc2ccccc2[nH]1
Show InChI InChI=1S/C8H7N/c1-2-4-8-7(3-1)5-6-9-8/h1-6,9H
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n/an/an/a 2.51E+4n/an/an/an/an/a



University of Chicago



Assay Description
Binding assay of L-trptophan and analogues to trp aporepressor


J Biol Chem 262: 4922-7 (1987)

More data for this
Ligand-Target Pair
Trp Aprorepressor


(Escherichia coli (strain K12))
BDBM92687
PNG
(1-Methyl-L-tryptophan, 8)
Show SMILES Cn1cc(CC(N)C([O-])=O)c2ccccc12
Show InChI InChI=1S/C12H14N2O2/c1-14-7-8(6-10(13)12(15)16)9-4-2-3-5-11(9)14/h2-5,7,10H,6,13H2,1H3,(H,15,16)/p-1
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n/an/an/a 2.64E+4n/an/an/an/an/a



University of Chicago



Assay Description
Binding assay of L-trptophan and analogues to trp aporepressor


J Biol Chem 262: 4922-7 (1987)

More data for this
Ligand-Target Pair
Trp Aprorepressor


(Escherichia coli (strain K12))
BDBM92688
PNG
(L-Tryptophanamide, 9)
Show SMILES NC(Cc1c[nH]c2ccccc12)C(N)=O
Show InChI InChI=1S/C11H13N3O/c12-9(11(13)15)5-7-6-14-10-4-2-1-3-8(7)10/h1-4,6,9,14H,5,12H2,(H2,13,15)
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n/an/an/a 2.77E+4n/an/an/an/an/a



University of Chicago



Assay Description
Binding assay of L-trptophan and analogues to trp aporepressor


J Biol Chem 262: 4922-7 (1987)

More data for this
Ligand-Target Pair
Trp Aprorepressor


(Escherichia coli (strain K12))
BDBM50073691
PNG
(2-(5-Methyl-1H-indol-3-yl)-ethylamine | 5-Methyl-t...)
Show SMILES Cc1ccc2[nH]cc(CCN)c2c1
Show InChI InChI=1S/C11H14N2/c1-8-2-3-11-10(6-8)9(4-5-12)7-13-11/h2-3,6-7,13H,4-5,12H2,1H3
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PubMed
n/an/an/a 2.88E+4n/an/an/an/an/a



University of Chicago



Assay Description
Binding assay of L-trptophan and analogues to trp aporepressor


J Biol Chem 262: 4922-7 (1987)

More data for this
Ligand-Target Pair
Trp Aprorepressor


(Escherichia coli (strain K12))
BDBM92689
PNG
(5-Methoxyu-L-tryptophan, 11)
Show SMILES COc1ccc2[nH]cc(CC([NH3+])C([O-])=O)c2c1
Show InChI InChI=1S/C12H14N2O3/c1-17-8-2-3-11-9(5-8)7(6-14-11)4-10(13)12(15)16/h2-3,5-6,10,14H,4,13H2,1H3,(H,15,16)
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PubMed
n/an/an/a 3.07E+4n/an/an/an/an/a



University of Chicago



Assay Description
Binding assay of L-trptophan and analogues to trp aporepressor


J Biol Chem 262: 4922-7 (1987)

More data for this
Ligand-Target Pair
Trp Aprorepressor


(Escherichia coli (strain K12))
BDBM92690
PNG
(L-Abrine, 12)
Show SMILES [O-]C(=O)C(Cc1c[nH]c2ccccc12)[NH+]=C
Show InChI InChI=1S/C12H12N2O2/c1-13-11(12(15)16)6-8-7-14-10-5-3-2-4-9(8)10/h2-5,7,11,14H,1,6H2,(H,15,16)
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PubMed
n/an/an/a 3.11E+4n/an/an/an/an/a



University of Chicago



Assay Description
Binding assay of L-trptophan and analogues to trp aporepressor


J Biol Chem 262: 4922-7 (1987)

More data for this
Ligand-Target Pair
Trp Aprorepressor


(Escherichia coli (strain K12))
BDBM92691
PNG
(L-Indole-3-lactic acid, 13)
Show SMILES OC(Cc1c[nH]c2ccccc12)C([O-])=O
Show InChI InChI=1S/C11H11NO3/c13-10(11(14)15)5-7-6-12-9-4-2-1-3-8(7)9/h1-4,6,10,12-13H,5H2,(H,14,15)/p-1
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PubMed
n/an/an/a 3.52E+4n/an/an/an/an/a



University of Chicago



Assay Description
Binding assay of L-trptophan and analogues to trp aporepressor


J Biol Chem 262: 4922-7 (1987)

More data for this
Ligand-Target Pair
Trp Aprorepressor


(Escherichia coli (strain K12))
BDBM92692
PNG
(L-Tryptophan methyl ester, 14)
Show SMILES COC(=O)C(N)Cc1c[nH]c2ccccc12
Show InChI InChI=1S/C12H14N2O2/c1-16-12(15)10(13)6-8-7-14-11-5-3-2-4-9(8)11/h2-5,7,10,14H,6,13H2,1H3
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n/an/an/a 3.71E+4n/an/an/an/an/a



University of Chicago



Assay Description
Binding assay of L-trptophan and analogues to trp aporepressor


J Biol Chem 262: 4922-7 (1987)

More data for this
Ligand-Target Pair
Trp Aprorepressor


(Escherichia coli (strain K12))
BDBM92693
PNG
(Tryptamine, 15)
Show SMILES [NH3+]CCc1c[nH]c2ccccc12
Show InChI InChI=1S/C10H12N2/c11-6-5-8-7-12-10-4-2-1-3-9(8)10/h1-4,7,12H,5-6,11H2/p+1
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n/an/an/a 4.11E+4n/an/an/an/an/a



University of Chicago



Assay Description
Binding assay of L-trptophan and analogues to trp aporepressor


J Biol Chem 262: 4922-7 (1987)

More data for this
Ligand-Target Pair
Trp Aprorepressor


(Escherichia coli (strain K12))
BDBM92694
PNG
(Indole-3-acetic acid, 16)
Show SMILES [O-]C(=O)Cc1c[nH]c2ccccc12
Show InChI InChI=1S/C10H9NO2/c12-10(13)5-7-6-11-9-4-2-1-3-8(7)9/h1-4,6,11H,5H2,(H,12,13)/p-1
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PubMed
n/an/an/a 7.29E+4n/an/an/an/an/a



University of Chicago



Assay Description
Binding assay of L-trptophan and analogues to trp aporepressor


J Biol Chem 262: 4922-7 (1987)

More data for this
Ligand-Target Pair
Trp Aprorepressor


(Escherichia coli (strain K12))
BDBM92695
PNG
(6-Nitro-L-tryptophan, 17)
Show SMILES [NH3+]C(Cc1c[nH]c2cc(ccc12)[N+]([O-])=O)C([O-])=O
Show InChI InChI=1S/C11H11N3O4/c12-9(11(15)16)3-6-5-13-10-4-7(14(17)18)1-2-8(6)10/h1-2,4-5,9,13H,3,12H2,(H,15,16)
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PubMed
n/an/an/a 7.56E+4n/an/an/an/an/a



University of Chicago



Assay Description
Binding assay of L-trptophan and analogues to trp aporepressor


J Biol Chem 262: 4922-7 (1987)

More data for this
Ligand-Target Pair
Trp Aprorepressor


(Escherichia coli (strain K12))
BDBM92696
PNG
(N-Formyl-L-tryptophan, 18)
Show SMILES [O-]C(=O)C(Cc1c[nH]c2ccccc12)[NH2+]C=O
Show InChI InChI=1S/C12H12N2O3/c15-7-14-11(12(16)17)5-8-6-13-10-4-2-1-3-9(8)10/h1-4,6-7,11,13H,5H2,(H,14,15)(H,16,17)
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PubMed
n/an/an/a 1.17E+5n/an/an/an/an/a



University of Chicago



Assay Description
Binding assay of L-trptophan and analogues to trp aporepressor


J Biol Chem 262: 4922-7 (1987)

More data for this
Ligand-Target Pair
Trp Aprorepressor


(Escherichia coli (strain K12))
BDBM92697
PNG
(Indoline, 19)
Show SMILES C1Cc2ccccc2N1
Show InChI InChI=1S/C8H9N/c1-2-4-8-7(3-1)5-6-9-8/h1-4,9H,5-6H2
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n/an/an/a 1.74E+5n/an/an/an/an/a



University of Chicago



Assay Description
Binding assay of L-trptophan and analogues to trp aporepressor


J Biol Chem 262: 4922-7 (1987)

More data for this
Ligand-Target Pair
Trp Aprorepressor


(Escherichia coli (strain K12))
BDBM92685
PNG
(D-Tryptophan, 20 | L-Tryptophan, 5)
Show SMILES [NH3+]C(Cc1c[nH]c2ccccc12)C([O-])=O
Show InChI InChI=1S/C11H12N2O2/c12-9(11(14)15)5-7-6-13-10-4-2-1-3-8(7)10/h1-4,6,9,13H,5,12H2,(H,14,15)
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PubMed
n/an/an/a 3.43E+5n/an/an/an/an/a



University of Chicago



Assay Description
Binding assay of L-trptophan and analogues to trp aporepressor


J Biol Chem 262: 4922-7 (1987)

More data for this
Ligand-Target Pair
Trp Aprorepressor


(Escherichia coli (strain K12))
BDBM92699
PNG
(7-Aza-L-tryptophan, 21)
Show SMILES [NH3+]C(Cc1c[nH]c2ncccc12)C([O-])=O
Show InChI InChI=1S/C10H11N3O2/c11-8(10(14)15)4-6-5-13-9-7(6)2-1-3-12-9/h1-3,5,8H,4,11H2,(H,12,13)(H,14,15)
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n/an/an/a 4.66E+5n/an/an/an/an/a



University of Chicago



Assay Description
Binding assay of L-trptophan and analogues to trp aporepressor


J Biol Chem 262: 4922-7 (1987)

More data for this
Ligand-Target Pair
Trp Aprorepressor


(Escherichia coli (strain K12))
BDBM92700
PNG
(5-Hydroxy-L-tryptophan, 22)
Show SMILES [NH3+]C(Cc1c[nH]c2ccc(O)cc12)C([O-])=O
Show InChI InChI=1S/C11H12N2O3/c12-9(11(15)16)3-6-5-13-10-2-1-7(14)4-8(6)10/h1-2,4-5,9,13-14H,3,12H2,(H,15,16)
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n/an/an/a 2.84E+6n/an/an/an/an/a



University of Chicago



Assay Description
Binding assay of L-trptophan and analogues to trp aporepressor


J Biol Chem 262: 4922-7 (1987)

More data for this
Ligand-Target Pair
Trp Aprorepressor


(Escherichia coli (strain K12))
BDBM92701
PNG
(L-Phenylalanine, 23)
Show SMILES [NH3+]C(Cc1ccccc1)C([O-])=O
Show InChI InChI=1S/C9H11NO2/c10-8(9(11)12)6-7-4-2-1-3-5-7/h1-5,8H,6,10H2,(H,11,12)
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n/an/an/a>3.00E+6n/an/an/an/an/a



University of Chicago



Assay Description
Binding assay of L-trptophan and analogues to trp aporepressor


J Biol Chem 262: 4922-7 (1987)

More data for this
Ligand-Target Pair
Trp Aprorepressor


(Escherichia coli (strain K12))
BDBM92682
PNG
(5-Methyl-L-tryptophan, 2)
Show SMILES Cc1ccc2[nH]cc(CC([NH3+])C([O-])=O)c2c1
Show InChI InChI=1S/C12H14N2O2/c1-7-2-3-11-9(4-7)8(6-14-11)5-10(13)12(15)16/h2-4,6,10,14H,5,13H2,1H3,(H,15,16)
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PubMed
n/an/an/a 3.25E+3n/an/an/an/an/a



University of Chicago



Assay Description
Binding assay of L-trptophan and analogues to trp aporepressor


J Biol Chem 262: 4922-7 (1987)

More data for this
Ligand-Target Pair