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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tryptophan 5-hydroxylase 2' AND taxid = 10116   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tryptophan 5-hydroxylase 2


(Rattus norvegicus)
BDBM50019142
PNG
(CHEMBL3288777)
Show SMILES CCOC(=O)CNC(=O)[C@]12CC[C@@H](C)[C@H](C)[C@H]1C1=CC[C@@H]3[C@@]4(C)Cc5nc6ccccc6nc5C(C)(C)[C@@H]4CC[C@@]3(C)[C@]1(C)CC2
Show InChI InChI=1S/C40H55N3O3/c1-9-46-32(44)23-41-35(45)40-19-16-24(2)25(3)33(40)26-14-15-31-37(6)22-29-34(43-28-13-11-10-12-27(28)42-29)36(4,5)30(37)17-18-39(31,8)38(26,7)20-21-40/h10-14,24-25,30-31,33H,9,15-23H2,1-8H3,(H,41,45)/t24-,25+,30+,31-,33+,37+,38-,39-,40+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 4.55E+4n/an/an/an/an/an/a



Nanjing University

Curated by ChEMBL


Assay Description
Inhibition of TPH-2-mediated serotonin biosynthesis in rat PC12 cells after 48 hrs by RP-HPLC analysis


Citation and Details
More data for this
Ligand-Target Pair