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Compile Data Set for Download or QSAR

Found 20 hits Enz. Inhib. hit(s) with Target = 'Tumor necrosis factor ligand superfamily member 10' AND taxid = 9606   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tumor necrosis factor ligand superfamily member 10


(Homo sapiens)
BDBM44372
PNG
(2-(dichloromethyl)-4-(4-methylphenyl)-6-(methylthi...)
Show SMILES CSc1nc(nc(n1)-c1ccc(C)cc1)C(Cl)Cl
Show InChI InChI=1S/C12H11Cl2N3S/c1-7-3-5-8(6-4-7)10-15-11(9(13)14)17-12(16-10)18-2/h3-6,9H,1-2H3
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n/an/a 372n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2009)

More data for this
Ligand-Target Pair
Tumor necrosis factor ligand superfamily member 10


(Homo sapiens)
BDBM44372
PNG
(2-(dichloromethyl)-4-(4-methylphenyl)-6-(methylthi...)
Show SMILES CSc1nc(nc(n1)-c1ccc(C)cc1)C(Cl)Cl
Show InChI InChI=1S/C12H11Cl2N3S/c1-7-3-5-8(6-4-7)10-15-11(9(13)14)17-12(16-10)18-2/h3-6,9H,1-2H3
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n/an/a 602n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2009)

More data for this
Ligand-Target Pair
Tumor necrosis factor ligand superfamily member 10


(Homo sapiens)
BDBM44374
PNG
(2-(dichloromethyl)-4-(methylthio)-6-(4-nitrophenyl...)
Show SMILES CSc1nc(nc(n1)-c1ccc(cc1)[N+]([O-])=O)C(Cl)Cl
Show InChI InChI=1S/C11H8Cl2N4O2S/c1-20-11-15-9(14-10(16-11)8(12)13)6-2-4-7(5-3-6)17(18)19/h2-5,8H,1H3
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n/an/a 683n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2009)

More data for this
Ligand-Target Pair
Tumor necrosis factor ligand superfamily member 10


(Homo sapiens)
BDBM44374
PNG
(2-(dichloromethyl)-4-(methylthio)-6-(4-nitrophenyl...)
Show SMILES CSc1nc(nc(n1)-c1ccc(cc1)[N+]([O-])=O)C(Cl)Cl
Show InChI InChI=1S/C11H8Cl2N4O2S/c1-20-11-15-9(14-10(16-11)8(12)13)6-2-4-7(5-3-6)17(18)19/h2-5,8H,1H3
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n/an/a 806n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2009)

More data for this
Ligand-Target Pair
Tumor necrosis factor ligand superfamily member 10


(Homo sapiens)
BDBM44372
PNG
(2-(dichloromethyl)-4-(4-methylphenyl)-6-(methylthi...)
Show SMILES CSc1nc(nc(n1)-c1ccc(C)cc1)C(Cl)Cl
Show InChI InChI=1S/C12H11Cl2N3S/c1-7-3-5-8(6-4-7)10-15-11(9(13)14)17-12(16-10)18-2/h3-6,9H,1-2H3
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n/an/a 3.27E+3n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2009)

More data for this
Ligand-Target Pair
Tumor necrosis factor ligand superfamily member 10


(Homo sapiens)
BDBM44372
PNG
(2-(dichloromethyl)-4-(4-methylphenyl)-6-(methylthi...)
Show SMILES CSc1nc(nc(n1)-c1ccc(C)cc1)C(Cl)Cl
Show InChI InChI=1S/C12H11Cl2N3S/c1-7-3-5-8(6-4-7)10-15-11(9(13)14)17-12(16-10)18-2/h3-6,9H,1-2H3
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n/an/a 4.81E+3n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2009)

More data for this
Ligand-Target Pair
Tumor necrosis factor ligand superfamily member 10


(Homo sapiens)
BDBM44369
PNG
(2-(4-chlorophenyl)-4-(ethylthio)-6-(1-pyrrolidinyl...)
Show SMILES CCSc1cc(nc(n1)-c1ccc(Cl)cc1)N1CCCC1
Show InChI InChI=1S/C16H18ClN3S/c1-2-21-15-11-14(20-9-3-4-10-20)18-16(19-15)12-5-7-13(17)8-6-12/h5-8,11H,2-4,9-10H2,1H3
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n/an/a>1.00E+4n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2009)

More data for this
Ligand-Target Pair
Tumor necrosis factor ligand superfamily member 10


(Homo sapiens)
BDBM44370
PNG
(4-methoxy-6-phenyl-1H-pyrimidine-2-thione | MLS-03...)
Show SMILES COc1cc(nc(=S)[nH]1)-c1ccccc1
Show InChI InChI=1S/C11H10N2OS/c1-14-10-7-9(12-11(15)13-10)8-5-3-2-4-6-8/h2-7H,1H3,(H,12,13,15)
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n/an/a>1.00E+4n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2009)

More data for this
Ligand-Target Pair
Tumor necrosis factor ligand superfamily member 10


(Homo sapiens)
BDBM44371
PNG
(2-(ethylthio)-6-phenyl-1H-pyrimidin-4-one | 2-ethy...)
Show SMILES CCSc1nc(cc(=O)[nH]1)-c1ccccc1
Show InChI InChI=1S/C12H12N2OS/c1-2-16-12-13-10(8-11(15)14-12)9-6-4-3-5-7-9/h3-8H,2H2,1H3,(H,13,14,15)
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n/an/a>1.00E+4n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2009)

More data for this
Ligand-Target Pair
Tumor necrosis factor ligand superfamily member 10


(Homo sapiens)
BDBM44373
PNG
(2-[4-phenyl-6-(trifluoromethyl)pyrimidin-2-yl]sulf...)
Show SMILES CC(Sc1nc(cc(n1)C(F)(F)F)-c1ccccc1)C(=O)N1CCCC1
Show InChI InChI=1S/C18H18F3N3OS/c1-12(16(25)24-9-5-6-10-24)26-17-22-14(13-7-3-2-4-8-13)11-15(23-17)18(19,20)21/h2-4,7-8,11-12H,5-6,9-10H2,1H3
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n/an/a>1.00E+4n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2009)

More data for this
Ligand-Target Pair
Tumor necrosis factor ligand superfamily member 10


(Homo sapiens)
BDBM44375
PNG
(MLS-0390927.0001 | [2-(4-methylsulfanyl-6-phenyl-1...)
Show SMILES CSc1nc(nc(n1)-c1ccccc1OC(C)=O)-c1ccccc1
Show InChI InChI=1S/C18H15N3O2S/c1-12(22)23-15-11-7-6-10-14(15)17-19-16(20-18(21-17)24-2)13-8-4-3-5-9-13/h3-11H,1-2H3
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n/an/a>1.00E+4n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2009)

More data for this
Ligand-Target Pair
Tumor necrosis factor ligand superfamily member 10


(Homo sapiens)
BDBM44376
PNG
(2-(methylthio)-4,6-diphenyl-1,3,5-triazine | 2-(me...)
Show SMILES CSc1nc(nc(n1)-c1ccccc1)-c1ccccc1
Show InChI InChI=1S/C16H13N3S/c1-20-16-18-14(12-8-4-2-5-9-12)17-15(19-16)13-10-6-3-7-11-13/h2-11H,1H3
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Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2009)

More data for this
Ligand-Target Pair
Tumor necrosis factor ligand superfamily member 10


(Homo sapiens)
BDBM44377
PNG
(2-(methylthio)-4-phenyl-6-propan-2-yl-1,3,5-triazi...)
Show SMILES CSc1nc(nc(n1)-c1ccccc1)C(C)C
Show InChI InChI=1S/C13H15N3S/c1-9(2)11-14-12(16-13(15-11)17-3)10-7-5-4-6-8-10/h4-9H,1-3H3
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n/an/a>1.00E+4n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2009)

More data for this
Ligand-Target Pair
Tumor necrosis factor ligand superfamily member 10


(Homo sapiens)
BDBM44377
PNG
(2-(methylthio)-4-phenyl-6-propan-2-yl-1,3,5-triazi...)
Show SMILES CSc1nc(nc(n1)-c1ccccc1)C(C)C
Show InChI InChI=1S/C13H15N3S/c1-9(2)11-14-12(16-13(15-11)17-3)10-7-5-4-6-8-10/h4-9H,1-3H3
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n/an/a>1.00E+4n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2009)

More data for this
Ligand-Target Pair
Tumor necrosis factor ligand superfamily member 10


(Homo sapiens)
BDBM44376
PNG
(2-(methylthio)-4,6-diphenyl-1,3,5-triazine | 2-(me...)
Show SMILES CSc1nc(nc(n1)-c1ccccc1)-c1ccccc1
Show InChI InChI=1S/C16H13N3S/c1-20-16-18-14(12-8-4-2-5-9-12)17-15(19-16)13-10-6-3-7-11-13/h2-11H,1H3
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n/an/a>1.00E+4n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2009)

More data for this
Ligand-Target Pair
Tumor necrosis factor ligand superfamily member 10


(Homo sapiens)
BDBM44375
PNG
(MLS-0390927.0001 | [2-(4-methylsulfanyl-6-phenyl-1...)
Show SMILES CSc1nc(nc(n1)-c1ccccc1OC(C)=O)-c1ccccc1
Show InChI InChI=1S/C18H15N3O2S/c1-12(22)23-15-11-7-6-10-14(15)17-19-16(20-18(21-17)24-2)13-8-4-3-5-9-13/h3-11H,1-2H3
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n/an/a>1.00E+4n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2009)

More data for this
Ligand-Target Pair
Tumor necrosis factor ligand superfamily member 10


(Homo sapiens)
BDBM44373
PNG
(2-[4-phenyl-6-(trifluoromethyl)pyrimidin-2-yl]sulf...)
Show SMILES CC(Sc1nc(cc(n1)C(F)(F)F)-c1ccccc1)C(=O)N1CCCC1
Show InChI InChI=1S/C18H18F3N3OS/c1-12(16(25)24-9-5-6-10-24)26-17-22-14(13-7-3-2-4-8-13)11-15(23-17)18(19,20)21/h2-4,7-8,11-12H,5-6,9-10H2,1H3
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n/an/a>1.00E+4n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2009)

More data for this
Ligand-Target Pair
Tumor necrosis factor ligand superfamily member 10


(Homo sapiens)
BDBM44371
PNG
(2-(ethylthio)-6-phenyl-1H-pyrimidin-4-one | 2-ethy...)
Show SMILES CCSc1nc(cc(=O)[nH]1)-c1ccccc1
Show InChI InChI=1S/C12H12N2OS/c1-2-16-12-13-10(8-11(15)14-12)9-6-4-3-5-7-9/h3-8H,2H2,1H3,(H,13,14,15)
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n/an/a>1.00E+4n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2009)

More data for this
Ligand-Target Pair
Tumor necrosis factor ligand superfamily member 10


(Homo sapiens)
BDBM44369
PNG
(2-(4-chlorophenyl)-4-(ethylthio)-6-(1-pyrrolidinyl...)
Show SMILES CCSc1cc(nc(n1)-c1ccc(Cl)cc1)N1CCCC1
Show InChI InChI=1S/C16H18ClN3S/c1-2-21-15-11-14(20-9-3-4-10-20)18-16(19-15)12-5-7-13(17)8-6-12/h5-8,11H,2-4,9-10H2,1H3
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n/an/a>1.00E+4n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2009)

More data for this
Ligand-Target Pair
Tumor necrosis factor ligand superfamily member 10


(Homo sapiens)
BDBM44370
PNG
(4-methoxy-6-phenyl-1H-pyrimidine-2-thione | MLS-03...)
Show SMILES COc1cc(nc(=S)[nH]1)-c1ccccc1
Show InChI InChI=1S/C11H10N2OS/c1-14-10-7-9(12-11(15)13-10)8-5-3-2-4-6-8/h2-7H,1H3,(H,12,13,15)
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n/an/a>1.00E+4n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2009)

More data for this
Ligand-Target Pair