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Compile Data Set for Download or QSAR

Found 1463 hits Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK2 [828-1132]'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine-protein kinase JAK2 [828-1132]


(Homo sapiens (Human))
BDBM197716
PNG
(US9216984, 1)
Show SMILES CCCCCC(CC#N)n1cc(cn1)-c1ncnc2[nH]ccc12
PDB

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 0.260n/an/an/an/a7.825



Incyte Corporation

US Patent


Assay Description
The compounds of the invention were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al.,...


US Patent US9216984 (2015)


BindingDB Entry DOI: 10.7270/Q26M35PV
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK2 [828-1132]


(Homo sapiens (Human))
BDBM197716
PNG
(US9216984, 1)
Show SMILES CCCCCC(CC#N)n1cc(cn1)-c1ncnc2[nH]ccc12
PDB

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 0.290n/an/an/an/a7.825



Incyte Corporation

US Patent


Assay Description
The compounds of the invention were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al.,...


US Patent US9216984 (2015)


BindingDB Entry DOI: 10.7270/Q26M35PV
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK2 [828-1132]


(Homo sapiens (Human))
BDBM197717
PNG
(US9216984, 2)
Show SMILES CCCCC(CC#N)n1cc(cn1)-c1ncnc2[nH]ccc12
PDB

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 0.300n/an/an/an/a7.825



Incyte Corporation

US Patent


Assay Description
The compounds of the invention were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al.,...


US Patent US9216984 (2015)


BindingDB Entry DOI: 10.7270/Q26M35PV
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK2 [828-1132]


(Homo sapiens (Human))
BDBM197717
PNG
(US9216984, 2)
Show SMILES CCCCC(CC#N)n1cc(cn1)-c1ncnc2[nH]ccc12
PDB

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 0.650n/an/an/an/a7.825



Incyte Corporation

US Patent


Assay Description
The compounds of the invention were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al.,...


US Patent US9216984 (2015)


BindingDB Entry DOI: 10.7270/Q26M35PV
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK2 [828-1132]


(Homo sapiens (Human))
BDBM197717
PNG
(US9216984, 2)
Show SMILES CCCCC(CC#N)n1cc(cn1)-c1ncnc2[nH]ccc12
PDB

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 1.40n/an/an/an/a7.825



Incyte Corporation

US Patent


Assay Description
The compounds of the invention were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al.,...


US Patent US9216984 (2015)


BindingDB Entry DOI: 10.7270/Q26M35PV
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK2 [828-1132]


(Homo sapiens (Human))
BDBM197716
PNG
(US9216984, 1)
Show SMILES CCCCCC(CC#N)n1cc(cn1)-c1ncnc2[nH]ccc12
PDB

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 2.20n/an/an/an/a7.825



Incyte Corporation

US Patent


Assay Description
The compounds of the invention were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al.,...


US Patent US9216984 (2015)


BindingDB Entry DOI: 10.7270/Q26M35PV
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK2 [828-1132]


(Homo sapiens (Human))
BDBM400317
PNG
(US10695337, Example 71 | US11285140, Example 71 | ...)
Show SMILES Oc1cc(sc1C(=O)N1CCC(CC1)N1CC(CC#N)(C1)n1cc(cn1)-c1ncnc2[nH]ccc12)C(F)(F)F
Show InChI InChI=1S/C25H23F3N8O2S/c26-25(27,28)19-9-18(37)21(39-19)23(38)34-7-2-16(3-8-34)35-12-24(13-35,4-5-29)36-11-15(10-33-36)20-17-1-6-30-22(17)32-14-31-20/h1,6,9-11,14,16,37H,2-4,7-8,12-13H2,(H,30,31,32)
PDB

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<5n/an/an/an/an/an/a



Incyte Holdings Corporation

US Patent


Assay Description
Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...


US Patent US9999619 (2018)


BindingDB Entry DOI: 10.7270/Q2C82CNM
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK2 [828-1132]


(Homo sapiens (Human))
BDBM400318
PNG
(US9999619, Example 73)
Show SMILES Oc1cscc1C(=O)N1CCC(CC1)N1CC(CC#N)(C1)n1cc(cn1)-c1ncnc2[nH]ccc12
Show InChI InChI=1S/C24H24N8O2S/c25-5-4-24(32-10-16(9-29-32)21-18-1-6-26-22(18)28-15-27-21)13-31(14-24)17-2-7-30(8-3-17)23(34)19-11-35-12-20(19)33/h1,6,9-12,15,17,33H,2-4,7-8,13-14H2,(H,26,27,28)
PDB

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<5n/an/an/an/an/an/a



Incyte Holdings Corporation

US Patent


Assay Description
Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...


US Patent US9999619 (2018)


BindingDB Entry DOI: 10.7270/Q2C82CNM
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK2 [828-1132]


(Homo sapiens (Human))
BDBM400320
PNG
(US10695337, Example 74 | US11285140, Example 74 | ...)
Show SMILES COc1c(Cl)scc1C(=O)N1CCC(CC1)N1CC(CC#N)(C1)n1cc(cn1)-c1ncnc2[nH]ccc12
Show InChI InChI=1S/C25H25ClN8O2S/c1-36-21-19(12-37-22(21)26)24(35)32-8-3-17(4-9-32)33-13-25(14-33,5-6-27)34-11-16(10-31-34)20-18-2-7-28-23(18)30-15-29-20/h2,7,10-12,15,17H,3-5,8-9,13-14H2,1H3,(H,28,29,30)
PDB

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<5n/an/an/an/an/an/a



Incyte Holdings Corporation

US Patent


Assay Description
Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...


US Patent US9999619 (2018)


BindingDB Entry DOI: 10.7270/Q2C82CNM
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK2 [828-1132]


(Homo sapiens (Human))
BDBM400321
PNG
(US10695337, Example 75 | US11285140, Example 75 | ...)
Show SMILES Brc1sccc1C(=O)N1CCC(CC1)N1CC(CC#N)(C1)n1cc(cn1)-c1ncnc2[nH]ccc12
Show InChI InChI=1S/C24H23BrN8OS/c25-21-19(4-10-35-21)23(34)31-8-2-17(3-9-31)32-13-24(14-32,5-6-26)33-12-16(11-30-33)20-18-1-7-27-22(18)29-15-28-20/h1,4,7,10-12,15,17H,2-3,5,8-9,13-14H2,(H,27,28,29)
PDB

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<5n/an/an/an/an/an/a



Incyte Holdings Corporation

US Patent


Assay Description
Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...


US Patent US9999619 (2018)


BindingDB Entry DOI: 10.7270/Q2C82CNM
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK2 [828-1132]


(Homo sapiens (Human))
BDBM400322
PNG
(US10695337, Example 76 | US11285140, Example 76 | ...)
Show SMILES Clc1ccsc1C(=O)N1CCC(CC1)N1CC(CC#N)(C1)n1cc(cn1)-c1ncnc2[nH]ccc12
Show InChI InChI=1S/C24H23ClN8OS/c25-19-4-10-35-21(19)23(34)31-8-2-17(3-9-31)32-13-24(14-32,5-6-26)33-12-16(11-30-33)20-18-1-7-27-22(18)29-15-28-20/h1,4,7,10-12,15,17H,2-3,5,8-9,13-14H2,(H,27,28,29)
PDB

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<5n/an/an/an/an/an/a



Incyte Holdings Corporation

US Patent


Assay Description
Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...


US Patent US9999619 (2018)


BindingDB Entry DOI: 10.7270/Q2C82CNM
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK2 [828-1132]


(Homo sapiens (Human))
BDBM400324
PNG
(US10695337, Example 78 | US11285140, Example 78 | ...)
Show SMILES Cc1ccsc1C(=O)N1CCC(CC1)N1CC(CC#N)(C1)n1cc(cn1)-c1ncnc2[nH]ccc12
Show InChI InChI=1S/C25H26N8OS/c1-17-5-11-35-22(17)24(34)31-9-3-19(4-10-31)32-14-25(15-32,6-7-26)33-13-18(12-30-33)21-20-2-8-27-23(20)29-16-28-21/h2,5,8,11-13,16,19H,3-4,6,9-10,14-15H2,1H3,(H,27,28,29)
PDB

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<5n/an/an/an/an/an/a



Incyte Holdings Corporation

US Patent


Assay Description
Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...


US Patent US9999619 (2018)


BindingDB Entry DOI: 10.7270/Q2C82CNM
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK2 [828-1132]


(Homo sapiens (Human))
BDBM400325
PNG
(US10695337, Example 79 | US9999619, Example 80)
Show SMILES Cc1csc(c1)C(=O)N1CCC(CC1)N1CC(CC#N)(C1)n1cc(cn1)-c1ncnc2[nH]ccc12
Show InChI InChI=1S/C25H26N8OS/c1-17-10-21(35-13-17)24(34)31-8-3-19(4-9-31)32-14-25(15-32,5-6-26)33-12-18(11-30-33)22-20-2-7-27-23(20)29-16-28-22/h2,7,10-13,16,19H,3-5,8-9,14-15H2,1H3,(H,27,28,29)
PDB

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<5n/an/an/an/an/an/a



Incyte Holdings Corporation

US Patent


Assay Description
Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...


US Patent US9999619 (2018)


BindingDB Entry DOI: 10.7270/Q2C82CNM
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK2 [828-1132]


(Homo sapiens (Human))
BDBM400326
PNG
(US10695337, Example 80 | US11285140, Example 80 | ...)
Show SMILES Cc1ccc(s1)C(=O)N1CCC(CC1)N1CC(CC#N)(C1)n1cc(cn1)-c1ncnc2[nH]ccc12
Show InChI InChI=1S/C25H26N8OS/c1-17-2-3-21(35-17)24(34)31-10-5-19(6-11-31)32-14-25(15-32,7-8-26)33-13-18(12-30-33)22-20-4-9-27-23(20)29-16-28-22/h2-4,9,12-13,16,19H,5-7,10-11,14-15H2,1H3,(H,27,28,29)
PDB

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<5n/an/an/an/an/an/a



Incyte Holdings Corporation

US Patent


Assay Description
Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...


US Patent US9999619 (2018)


BindingDB Entry DOI: 10.7270/Q2C82CNM
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK2 [828-1132]


(Homo sapiens (Human))
BDBM400327
PNG
(US10695337, Example 81 | US11285140, Example 81 | ...)
Show SMILES COc1ccsc1C(=O)N1CCC(CC1)N1CC(CC#N)(C1)n1cc(cn1)-c1ncnc2[nH]ccc12
Show InChI InChI=1S/C25H26N8O2S/c1-35-20-5-11-36-22(20)24(34)31-9-3-18(4-10-31)32-14-25(15-32,6-7-26)33-13-17(12-30-33)21-19-2-8-27-23(19)29-16-28-21/h2,5,8,11-13,16,18H,3-4,6,9-10,14-15H2,1H3,(H,27,28,29)
PDB

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<5n/an/an/an/an/an/a



Incyte Holdings Corporation

US Patent


Assay Description
Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...


US Patent US9999619 (2018)


BindingDB Entry DOI: 10.7270/Q2C82CNM
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK2 [828-1132]


(Homo sapiens (Human))
BDBM400332
PNG
(US10695337, Example 86 | US11285140, Example 86 | ...)
Show SMILES FC(F)(F)c1cncc(n1)C(=O)N1CCC(CC1)N1CC(CC#N)(C1)n1cc(cn1)-c1ncnc2[nH]ccc12
Show InChI InChI=1S/C25H23F3N10O/c26-25(27,28)20-11-30-10-19(35-20)23(39)36-7-2-17(3-8-36)37-13-24(14-37,4-5-29)38-12-16(9-34-38)21-18-1-6-31-22(18)33-15-32-21/h1,6,9-12,15,17H,2-4,7-8,13-14H2,(H,31,32,33)
PDB

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<5n/an/an/an/an/an/a



Incyte Holdings Corporation

US Patent


Assay Description
Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...


US Patent US9999619 (2018)


BindingDB Entry DOI: 10.7270/Q2C82CNM
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK2 [828-1132]


(Homo sapiens (Human))
BDBM400333
PNG
(US10695337, Example 87 | US11285140, Example 87 | ...)
Show SMILES O=C(N1CCC(CC1)N1CC(CC#N)(C1)n1cc(cn1)-c1ncnc2[nH]ccc12)c1cccc2ccccc12
Show InChI InChI=1S/C30H28N8O/c31-12-11-30(38-17-22(16-35-38)27-26-8-13-32-28(26)34-20-33-27)18-37(19-30)23-9-14-36(15-10-23)29(39)25-7-3-5-21-4-1-2-6-24(21)25/h1-8,13,16-17,20,23H,9-11,14-15,18-19H2,(H,32,33,34)
PDB

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<5n/an/an/an/an/an/a



Incyte Holdings Corporation

US Patent


Assay Description
Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...


US Patent US9999619 (2018)


BindingDB Entry DOI: 10.7270/Q2C82CNM
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK2 [828-1132]


(Homo sapiens (Human))
BDBM400334
PNG
(US11285140, Example 88 | US9999619, Example 89)
Show SMILES O=C(N1CCC(CC1)N1CC(CC#N)(C1)n1cc(cn1)-c1ncnc2[nH]ccc12)c1cnc2ccccc2c1
Show InChI InChI=1S/C29H27N9O/c30-9-8-29(38-16-22(15-35-38)26-24-5-10-31-27(24)34-19-33-26)17-37(18-29)23-6-11-36(12-7-23)28(39)21-13-20-3-1-2-4-25(20)32-14-21/h1-5,10,13-16,19,23H,6-8,11-12,17-18H2,(H,31,33,34)
PDB

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<5n/an/an/an/an/an/a



Incyte Holdings Corporation

US Patent


Assay Description
Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...


US Patent US9999619 (2018)


BindingDB Entry DOI: 10.7270/Q2C82CNM
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK2 [828-1132]


(Homo sapiens (Human))
BDBM400335
PNG
(US10695337, Example 89 | US11285140, Example 89 | ...)
Show SMILES O=C(N1CCC(CC1)N1CC(CC#N)(C1)n1cc(cn1)-c1ncnc2[nH]ccc12)c1ccc2ncccc2c1
Show InChI InChI=1S/C29H27N9O/c30-9-8-29(38-16-22(15-35-38)26-24-5-11-32-27(24)34-19-33-26)17-37(18-29)23-6-12-36(13-7-23)28(39)21-3-4-25-20(14-21)2-1-10-31-25/h1-5,10-11,14-16,19,23H,6-8,12-13,17-18H2,(H,32,33,34)
PDB

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<5n/an/an/an/an/an/a



Incyte Holdings Corporation

US Patent


Assay Description
Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...


US Patent US9999619 (2018)


BindingDB Entry DOI: 10.7270/Q2C82CNM
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK2 [828-1132]


(Homo sapiens (Human))
BDBM400336
PNG
(US10695337, Example 90 | US11285140, Example 90 | ...)
Show SMILES O=C(N1CCC(CC1)N1CC(CC#N)(C1)n1cc(cn1)-c1ncnc2[nH]ccc12)c1cc2ccccc2s1
Show InChI InChI=1S/C28H26N8OS/c29-9-8-28(36-15-20(14-33-36)25-22-5-10-30-26(22)32-18-31-25)16-35(17-28)21-6-11-34(12-7-21)27(37)24-13-19-3-1-2-4-23(19)38-24/h1-5,10,13-15,18,21H,6-8,11-12,16-17H2,(H,30,31,32)
PDB

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PC cid
PC sid
UniChem
US Patent
n/an/a<5n/an/an/an/an/an/a



Incyte Holdings Corporation

US Patent


Assay Description
Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...


US Patent US9999619 (2018)


BindingDB Entry DOI: 10.7270/Q2C82CNM
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK2 [828-1132]


(Homo sapiens (Human))
BDBM400337
PNG
(US10695337, Example 91 | US11285140, Example 91 | ...)
Show SMILES Fc1ccc2c(Cl)c(sc2c1)C(=O)N1CCC(CC1)N1CC(CC#N)(C1)n1cc(cn1)-c1ncnc2[nH]ccc12
Show InChI InChI=1S/C28H24ClFN8OS/c29-23-20-2-1-18(30)11-22(20)40-25(23)27(39)36-9-4-19(5-10-36)37-14-28(15-37,6-7-31)38-13-17(12-35-38)24-21-3-8-32-26(21)34-16-33-24/h1-3,8,11-13,16,19H,4-6,9-10,14-15H2,(H,32,33,34)
PDB

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PC cid
PC sid
UniChem
US Patent
n/an/a<5n/an/an/an/an/an/a



Incyte Holdings Corporation

US Patent


Assay Description
Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...


US Patent US9999619 (2018)


BindingDB Entry DOI: 10.7270/Q2C82CNM
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK2 [828-1132]


(Homo sapiens (Human))
BDBM400338
PNG
(US10695337, Example 92 | US11285140, Example 92 | ...)
Show SMILES Fc1cccc2sc(C(=O)N3CCC(CC3)N3CC(CC#N)(C3)n3cc(cn3)-c3ncnc4[nH]ccc34)c(Cl)c12
Show InChI InChI=1S/C28H24ClFN8OS/c29-23-22-20(30)2-1-3-21(22)40-25(23)27(39)36-10-5-18(6-11-36)37-14-28(15-37,7-8-31)38-13-17(12-35-38)24-19-4-9-32-26(19)34-16-33-24/h1-4,9,12-13,16,18H,5-7,10-11,14-15H2,(H,32,33,34)
PDB

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PC cid
PC sid
UniChem
US Patent
n/an/a<5n/an/an/an/an/an/a



Incyte Holdings Corporation

US Patent


Assay Description
Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...


US Patent US9999619 (2018)


BindingDB Entry DOI: 10.7270/Q2C82CNM
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK2 [828-1132]


(Homo sapiens (Human))
BDBM400340
PNG
(US10695337, Example 94 | US11285140, Example 94 | ...)
Show SMILES FC(F)(F)c1ccc2cc(sc2c1)C(=O)N1CCC(CC1)N1CC(CC#N)(C1)n1cc(cn1)-c1ncnc2[nH]ccc12
Show InChI InChI=1S/C29H25F3N8OS/c30-29(31,32)20-2-1-18-11-24(42-23(18)12-20)27(41)38-9-4-21(5-10-38)39-15-28(16-39,6-7-33)40-14-19(13-37-40)25-22-3-8-34-26(22)36-17-35-25/h1-3,8,11-14,17,21H,4-6,9-10,15-16H2,(H,34,35,36)
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Assay Description
Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...


US Patent US9999619 (2018)


BindingDB Entry DOI: 10.7270/Q2C82CNM
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK2 [828-1132]


(Homo sapiens (Human))
BDBM400341
PNG
(US10695337, Example 95 | US11285140, Example 95 | ...)
Show SMILES FC(F)(F)c1cccc2cc(sc12)C(=O)N1CCC(CC1)N1CC(CC#N)(C1)n1cc(cn1)-c1ncnc2[nH]ccc12
Show InChI InChI=1S/C29H25F3N8OS/c30-29(31,32)22-3-1-2-18-12-23(42-25(18)22)27(41)38-10-5-20(6-11-38)39-15-28(16-39,7-8-33)40-14-19(13-37-40)24-21-4-9-34-26(21)36-17-35-24/h1-4,9,12-14,17,20H,5-7,10-11,15-16H2,(H,34,35,36)
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Assay Description
Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...


US Patent US9999619 (2018)


BindingDB Entry DOI: 10.7270/Q2C82CNM
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK2 [828-1132]


(Homo sapiens (Human))
BDBM400365
PNG
(US10695337, Example 119 | US11285140, Example 119 ...)
Show SMILES Fc1cc(ccc1C#N)-c1ccc(cc1F)C(=O)N1CCC(CC1)N1CC(CC#N)(C1)n1cc(cn1)-c1ncnc2[nH]ccc12
Show InChI InChI=1S/C33H27F2N9O/c34-28-13-21(1-2-23(28)15-37)26-4-3-22(14-29(26)35)32(45)42-11-6-25(7-12-42)43-18-33(19-43,8-9-36)44-17-24(16-41-44)30-27-5-10-38-31(27)40-20-39-30/h1-5,10,13-14,16-17,20,25H,6-8,11-12,18-19H2,(H,38,39,40)
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Assay Description
Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...


US Patent US9999619 (2018)


BindingDB Entry DOI: 10.7270/Q2C82CNM
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK2 [828-1132]


(Homo sapiens (Human))
BDBM400366
PNG
(US10695337, Example 120 | US11285140, Example 120 ...)
Show SMILES Fc1cc(ccc1C(=O)N1CCC(CC1)N1CC(CC#N)(C1)n1cc(cn1)-c1ncnc2[nH]ccc12)-c1cccnc1
Show InChI InChI=1S/C31H28FN9O/c32-27-14-21(22-2-1-10-34-15-22)3-4-25(27)30(42)39-12-6-24(7-13-39)40-18-31(19-40,8-9-33)41-17-23(16-38-41)28-26-5-11-35-29(26)37-20-36-28/h1-5,10-11,14-17,20,24H,6-8,12-13,18-19H2,(H,35,36,37)
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Assay Description
Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...


US Patent US9999619 (2018)


BindingDB Entry DOI: 10.7270/Q2C82CNM
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK2 [828-1132]


(Homo sapiens (Human))
BDBM400368
PNG
(US10695337, Example 122 | US11285140, Example 122 ...)
Show SMILES Fc1cc(ccc1-c1nccs1)C(=O)N1CCC(CC1)N1CC(CC#N)(C1)n1cc(cn1)-c1ncnc2[nH]ccc12
Show InChI InChI=1S/C29H26FN9OS/c30-24-13-19(1-2-22(24)27-33-9-12-41-27)28(40)37-10-4-21(5-11-37)38-16-29(17-38,6-7-31)39-15-20(14-36-39)25-23-3-8-32-26(23)35-18-34-25/h1-3,8-9,12-15,18,21H,4-6,10-11,16-17H2,(H,32,34,35)
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Assay Description
Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...


US Patent US9999619 (2018)


BindingDB Entry DOI: 10.7270/Q2C82CNM
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK2 [828-1132]


(Homo sapiens (Human))
BDBM400369
PNG
(US10695337, Example 123 | US11285140, Example 123 ...)
Show SMILES Fc1cc(ccc1-c1cccnc1)C(=O)N1CCC(CC1)N1CC(CC#N)(C1)n1cc(cn1)-c1ncnc2[nH]ccc12
Show InChI InChI=1S/C31H28FN9O/c32-27-14-21(3-4-25(27)22-2-1-10-34-15-22)30(42)39-12-6-24(7-13-39)40-18-31(19-40,8-9-33)41-17-23(16-38-41)28-26-5-11-35-29(26)37-20-36-28/h1-5,10-11,14-17,20,24H,6-8,12-13,18-19H2,(H,35,36,37)
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Assay Description
Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...


US Patent US9999619 (2018)


BindingDB Entry DOI: 10.7270/Q2C82CNM
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK2 [828-1132]


(Homo sapiens (Human))
BDBM400374
PNG
(US10695337, Example 128 | US11285140, Example 128 ...)
Show SMILES Fc1cc(cc(c1)-c1ccc(cc1F)C(=O)N1CCC(CC1)N1CC(CC#N)(C1)n1cc(cn1)-c1ncnc2[nH]ccc12)C#N
Show InChI InChI=1S/C33H27F2N9O/c34-25-12-21(15-37)11-23(13-25)27-2-1-22(14-29(27)35)32(45)42-9-4-26(5-10-42)43-18-33(19-43,6-7-36)44-17-24(16-41-44)30-28-3-8-38-31(28)40-20-39-30/h1-3,8,11-14,16-17,20,26H,4-6,9-10,18-19H2,(H,38,39,40)
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Assay Description
Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...


US Patent US9999619 (2018)


BindingDB Entry DOI: 10.7270/Q2C82CNM
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK2 [828-1132]


(Homo sapiens (Human))
BDBM400375
PNG
(US10695337, Example 129 | US11285140, Example 129 ...)
Show SMILES Fc1cc(ccc1-c1cccc2ncccc12)C(=O)N1CCC(CC1)N1CC(CC#N)(C1)n1cc(cn1)-c1ncnc2[nH]ccc12
Show InChI InChI=1S/C35H30FN9O/c36-30-17-23(6-7-27(30)26-3-1-5-31-28(26)4-2-13-38-31)34(46)43-15-9-25(10-16-43)44-20-35(21-44,11-12-37)45-19-24(18-42-45)32-29-8-14-39-33(29)41-22-40-32/h1-8,13-14,17-19,22,25H,9-11,15-16,20-21H2,(H,39,40,41)
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Assay Description
Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...


US Patent US9999619 (2018)


BindingDB Entry DOI: 10.7270/Q2C82CNM
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK2 [828-1132]


(Homo sapiens (Human))
BDBM400377
PNG
(US10695337, Example 131 | US11285140, Example 131 ...)
Show SMILES Fc1cc(ccc1-c1cccc2ccncc12)C(=O)N1CCC(CC1)N1CC(CC#N)(C1)n1cc(cn1)-c1ncnc2[nH]ccc12
Show InChI InChI=1S/C35H30FN9O/c36-31-16-24(4-5-28(31)27-3-1-2-23-6-12-38-18-30(23)27)34(46)43-14-8-26(9-15-43)44-20-35(21-44,10-11-37)45-19-25(17-42-45)32-29-7-13-39-33(29)41-22-40-32/h1-7,12-13,16-19,22,26H,8-10,14-15,20-21H2,(H,39,40,41)
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Assay Description
Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...


US Patent US9999619 (2018)


BindingDB Entry DOI: 10.7270/Q2C82CNM
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK2 [828-1132]


(Homo sapiens (Human))
BDBM400383
PNG
(3-[(3-{3-(Cyanomethyl)-3-[4-(7H-pyrrolo[2,3-d]pyri...)
Show SMILES Fc1cc(cc(c1)C(=O)N1C2CCC1CC(C2)N1CC(CC#N)(C1)n1cc(cn1)-c1ncnc2[nH]ccc12)C#N
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Assay Description
Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...


US Patent US9999619 (2018)


BindingDB Entry DOI: 10.7270/Q2C82CNM
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK2 [828-1132]


(Homo sapiens (Human))
BDBM400384
PNG
(US10695337, Example 139 | US11285140, Example 139 ...)
Show SMILES Fc1ccc(cc1F)C(=O)N1C2CCC1CC(C2)N1CC(CC#N)(C1)n1cc(cn1)-c1ncnc2[nH]ccc12
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Assay Description
Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...


US Patent US9999619 (2018)


BindingDB Entry DOI: 10.7270/Q2C82CNM
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK2 [828-1132]


(Homo sapiens (Human))
BDBM400386
PNG
(US10695337, Example 140 | US11285140, Example 140 ...)
Show SMILES Fc1cc(ccc1C#N)C(=O)N1C2CCC1CC(C2)N1CC(CC#N)(C1)n1cc(cn1)-c1ncnc2[nH]ccc12
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Assay Description
Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...


US Patent US9999619 (2018)


BindingDB Entry DOI: 10.7270/Q2C82CNM
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK2 [828-1132]


(Homo sapiens (Human))
BDBM400387
PNG
(US10695337, Example 141 | US11285140, Example 141 ...)
Show SMILES Fc1cc(ccc1Cl)C(=O)N1C2CCC1CC(C2)N1CC(CC#N)(C1)n1cc(cn1)-c1ncnc2[nH]ccc12
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Assay Description
Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...


US Patent US9999619 (2018)


BindingDB Entry DOI: 10.7270/Q2C82CNM
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK2 [828-1132]


(Homo sapiens (Human))
BDBM400392
PNG
(US10695337, Example 146 | US11285140, Example 146 ...)
Show SMILES O=C(C1CCOCC1)N1C2CCC1CC(C2)N1CC(CC#N)(C1)n1cc(cn1)-c1ncnc2[nH]ccc12
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Assay Description
Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...


US Patent US9999619 (2018)


BindingDB Entry DOI: 10.7270/Q2C82CNM
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK2 [828-1132]


(Homo sapiens (Human))
BDBM400393
PNG
(US10695337, Example 147 | US11285140, Example 147 ...)
Show SMILES O=C(C1CCCCC1)N1C2CCC1CC(C2)N1CC(CC#N)(C1)n1cc(cn1)-c1ncnc2[nH]ccc12
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Assay Description
Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...


US Patent US9999619 (2018)


BindingDB Entry DOI: 10.7270/Q2C82CNM
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK2 [828-1132]


(Homo sapiens (Human))
BDBM400394
PNG
(Diastereomers of {1-[1-(3-fluorobenzoyl)-2-methylp...)
Show SMILES CC1CC(CCN1C(=O)c1cccc(F)c1)N1CC(CC#N)(C1)n1cc(cn1)-c1ncnc2[nH]ccc12
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Assay Description
Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...


US Patent US9999619 (2018)


BindingDB Entry DOI: 10.7270/Q2C82CNM
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK2 [828-1132]


(Homo sapiens (Human))
BDBM400411
PNG
(US10695337, Example 166 | US11285140, Example 166 ...)
Show SMILES FC(F)(F)c1cccc(NC(=O)N2CCC(CC2)N2CC(CC#N)(C2)n2cc(cn2)-c2ncnc3[nH]ccc23)c1
Show InChI InChI=1S/C27H26F3N9O/c28-27(29,30)19-2-1-3-20(12-19)36-25(40)37-10-5-21(6-11-37)38-15-26(16-38,7-8-31)39-14-18(13-35-39)23-22-4-9-32-24(22)34-17-33-23/h1-4,9,12-14,17,21H,5-7,10-11,15-16H2,(H,36,40)(H,32,33,34)
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Assay Description
Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...


US Patent US9999619 (2018)


BindingDB Entry DOI: 10.7270/Q2C82CNM
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK2 [828-1132]


(Homo sapiens (Human))
BDBM400412
PNG
(US10695337, Example 167 | US11285140, Example 167 ...)
Show SMILES FC(F)(F)c1ccc(NC(=O)N2CCC(CC2)N2CC(CC#N)(C2)n2cc(cn2)-c2ncnc3[nH]ccc23)cc1
Show InChI InChI=1S/C27H26F3N9O/c28-27(29,30)19-1-3-20(4-2-19)36-25(40)37-11-6-21(7-12-37)38-15-26(16-38,8-9-31)39-14-18(13-35-39)23-22-5-10-32-24(22)34-17-33-23/h1-5,10,13-14,17,21H,6-8,11-12,15-16H2,(H,36,40)(H,32,33,34)
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Assay Description
Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...


US Patent US9999619 (2018)


BindingDB Entry DOI: 10.7270/Q2C82CNM
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK2 [828-1132]


(Homo sapiens (Human))
BDBM400413
PNG
(US10695337, Example 168 | US11285140, Example 168 ...)
Show SMILES Cc1ccc(Cl)cc1NC(=O)N1CCC(CC1)N1CC(CC#N)(C1)n1cc(cn1)-c1ncnc2[nH]ccc12
Show InChI InChI=1S/C27H28ClN9O/c1-18-2-3-20(28)12-23(18)34-26(38)35-10-5-21(6-11-35)36-15-27(16-36,7-8-29)37-14-19(13-33-37)24-22-4-9-30-25(22)32-17-31-24/h2-4,9,12-14,17,21H,5-7,10-11,15-16H2,1H3,(H,34,38)(H,30,31,32)
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Assay Description
Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...


US Patent US9999619 (2018)


BindingDB Entry DOI: 10.7270/Q2C82CNM
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK2 [828-1132]


(Homo sapiens (Human))
BDBM400419
PNG
(US11285140, Example 174 | US9999619, Example 174)
Show SMILES Fc1ccc(F)c(NC(=O)N2CCC(CC2)N2CC(CC#N)(C2)n2cc(cn2)-c2ncnc3[nH]ccc23)c1
Show InChI InChI=1S/C26H25F2N9O/c27-18-1-2-21(28)22(11-18)34-25(38)35-9-4-19(5-10-35)36-14-26(15-36,6-7-29)37-13-17(12-33-37)23-20-3-8-30-24(20)32-16-31-23/h1-3,8,11-13,16,19H,4-6,9-10,14-15H2,(H,34,38)(H,30,31,32)
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Assay Description
Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...


US Patent US9999619 (2018)


BindingDB Entry DOI: 10.7270/Q2C82CNM
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK2 [828-1132]


(Homo sapiens (Human))
BDBM400420
PNG
(US11285140, Example 175 | US9999619, Example 175)
Show SMILES Fc1cc(F)cc(NC(=O)N2CCC(CC2)N2CC(CC#N)(C2)n2cc(cn2)-c2ncnc3[nH]ccc23)c1
Show InChI InChI=1S/C26H25F2N9O/c27-18-9-19(28)11-20(10-18)34-25(38)35-7-2-21(3-8-35)36-14-26(15-36,4-5-29)37-13-17(12-33-37)23-22-1-6-30-24(22)32-16-31-23/h1,6,9-13,16,21H,2-4,7-8,14-15H2,(H,34,38)(H,30,31,32)
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Assay Description
Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...


US Patent US9999619 (2018)


BindingDB Entry DOI: 10.7270/Q2C82CNM
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK2 [828-1132]


(Homo sapiens (Human))
BDBM400421
PNG
(US11285140, Example 176 | US9999619, Example 176)
Show SMILES Fc1ccc(NC(=O)N2CCC(CC2)N2CC(CC#N)(C2)n2cc(cn2)-c2ncnc3[nH]ccc23)cc1F
Show InChI InChI=1S/C26H25F2N9O/c27-21-2-1-18(11-22(21)28)34-25(38)35-9-4-19(5-10-35)36-14-26(15-36,6-7-29)37-13-17(12-33-37)23-20-3-8-30-24(20)32-16-31-23/h1-3,8,11-13,16,19H,4-6,9-10,14-15H2,(H,34,38)(H,30,31,32)
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Assay Description
Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...


US Patent US9999619 (2018)


BindingDB Entry DOI: 10.7270/Q2C82CNM
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK2 [828-1132]


(Homo sapiens (Human))
BDBM400422
PNG
(US10695337, Example 177 | US11285140, Example 177 ...)
Show SMILES Fc1c(Cl)cccc1NC(=O)N1CCC(CC1)N1CC(CC#N)(C1)n1cc(cn1)-c1ncnc2[nH]ccc12
Show InChI InChI=1S/C26H25ClFN9O/c27-20-2-1-3-21(22(20)28)34-25(38)35-10-5-18(6-11-35)36-14-26(15-36,7-8-29)37-13-17(12-33-37)23-19-4-9-30-24(19)32-16-31-23/h1-4,9,12-13,16,18H,5-7,10-11,14-15H2,(H,34,38)(H,30,31,32)
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n/an/a<5n/an/an/an/an/an/a



Incyte Holdings Corporation

US Patent


Assay Description
Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...


US Patent US9999619 (2018)


BindingDB Entry DOI: 10.7270/Q2C82CNM
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK2 [828-1132]


(Homo sapiens (Human))
BDBM400423
PNG
(US10695337, Example 178 | US11285140, Example 178 ...)
Show SMILES Fc1cc(Cl)ccc1NC(=O)N1CCC(CC1)N1CC(CC#N)(C1)n1cc(cn1)-c1ncnc2[nH]ccc12
Show InChI InChI=1S/C26H25ClFN9O/c27-18-1-2-22(21(28)11-18)34-25(38)35-9-4-19(5-10-35)36-14-26(15-36,6-7-29)37-13-17(12-33-37)23-20-3-8-30-24(20)32-16-31-23/h1-3,8,11-13,16,19H,4-6,9-10,14-15H2,(H,34,38)(H,30,31,32)
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Incyte Holdings Corporation

US Patent


Assay Description
Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...


US Patent US9999619 (2018)


BindingDB Entry DOI: 10.7270/Q2C82CNM
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK2 [828-1132]


(Homo sapiens (Human))
BDBM400428
PNG
(US10695337, Example 183 | US11285140, Example 183 ...)
Show SMILES Clc1cccc(NC(=O)N2CCC(CC2)N2CC(CC#N)(C2)n2cc(cn2)-c2ncnc3[nH]ccc23)c1
Show InChI InChI=1S/C26H26ClN9O/c27-19-2-1-3-20(12-19)33-25(37)34-10-5-21(6-11-34)35-15-26(16-35,7-8-28)36-14-18(13-32-36)23-22-4-9-29-24(22)31-17-30-23/h1-4,9,12-14,17,21H,5-7,10-11,15-16H2,(H,33,37)(H,29,30,31)
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Incyte Holdings Corporation

US Patent


Assay Description
Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...


US Patent US9999619 (2018)


BindingDB Entry DOI: 10.7270/Q2C82CNM
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK2 [828-1132]


(Homo sapiens (Human))
BDBM400429
PNG
(US10695337, Example 184 | US11285140, Example 184 ...)
Show SMILES Clc1ccc(NC(=O)N2CCC(CC2)N2CC(CC#N)(C2)n2cc(cn2)-c2ncnc3[nH]ccc23)cc1
Show InChI InChI=1S/C26H26ClN9O/c27-19-1-3-20(4-2-19)33-25(37)34-11-6-21(7-12-34)35-15-26(16-35,8-9-28)36-14-18(13-32-36)23-22-5-10-29-24(22)31-17-30-23/h1-5,10,13-14,17,21H,6-8,11-12,15-16H2,(H,33,37)(H,29,30,31)
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Incyte Holdings Corporation

US Patent


Assay Description
Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...


US Patent US9999619 (2018)


BindingDB Entry DOI: 10.7270/Q2C82CNM
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK2 [828-1132]


(Homo sapiens (Human))
BDBM400438
PNG
(US10695337, Example 193 | US11285140, Example 193 ...)
Show SMILES O=C(Nc1nc2ccccc2s1)N1CCC(CC1)N1CC(CC#N)(C1)n1cc(cn1)-c1ncnc2[nH]ccc12
Show InChI InChI=1S/C27H26N10OS/c28-9-8-27(37-14-18(13-32-37)23-20-5-10-29-24(20)31-17-30-23)15-36(16-27)19-6-11-35(12-7-19)26(38)34-25-33-21-3-1-2-4-22(21)39-25/h1-5,10,13-14,17,19H,6-8,11-12,15-16H2,(H,29,30,31)(H,33,34,38)
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Incyte Holdings Corporation

US Patent


Assay Description
Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...


US Patent US9999619 (2018)


BindingDB Entry DOI: 10.7270/Q2C82CNM
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK2 [828-1132]


(Homo sapiens (Human))
BDBM400439
PNG
(US10695337, Example 194 | US11285140, Example 194 ...)
Show SMILES Cn1c(NC(=O)N2CCC(CC2)N2CC(CC#N)(C2)n2cc(cn2)-c2ncnc3[nH]ccc23)nc2ccccc12
Show InChI InChI=1S/C28H29N11O/c1-36-23-5-3-2-4-22(23)34-26(36)35-27(40)37-12-7-20(8-13-37)38-16-28(17-38,9-10-29)39-15-19(14-33-39)24-21-6-11-30-25(21)32-18-31-24/h2-6,11,14-15,18,20H,7-9,12-13,16-17H2,1H3,(H,30,31,32)(H,34,35,40)
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n/an/a<5n/an/an/an/an/an/a



Incyte Holdings Corporation

US Patent


Assay Description
Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...


US Patent US9999619 (2018)


BindingDB Entry DOI: 10.7270/Q2C82CNM
More data for this
Ligand-Target Pair
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