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Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'UDP-N-acetylmuramoylalanine--D-glutamate ligase (MurgD)' AND taxid = 189518   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
UDP-N-acetylmuramoylalanine--D-glutamate ligase (MurgD)


(Leptospira interrogans)
BDBM81616
PNG
(Phosphinate inhibitor 2)
Show SMILES C[C@H](NS(=O)(=O)Cc1ccc(cc1)N(=O)=O)C(=O)N[C@@H](C)P(O)(=O)CC(CCC(O)=O)C(O)=O
Show InChI InChI=1S/C18H26N3O11PS/c1-11(20-34(31,32)10-13-3-6-15(7-4-13)21(27)28)17(24)19-12(2)33(29,30)9-14(18(25)26)5-8-16(22)23/h3-4,6-7,11-12,14,20H,5,8-10H2,1-2H3,(H,19,24)(H,22,23)(H,25,26)(H,29,30)/t11-,12+,14?/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 7.80E+4n/an/an/an/an/an/a



SVIMS University



Assay Description
Inhibiton assay using MurgD.


Citation and Details
More data for this
Ligand-Target Pair
UDP-N-acetylmuramoylalanine--D-glutamate ligase (MurgD)


(Leptospira interrogans)
BDBM81615
PNG
(Phosphinate inhibitor 1)
Show SMILES C[C@@H](NC(=O)C=Cc1ccc2OCOc2c1)P(O)(=O)CC(CCC(O)=O)C(O)=O
Show InChI InChI=1S/C18H22NO9P/c1-11(29(25,26)9-13(18(23)24)4-7-17(21)22)19-16(20)6-3-12-2-5-14-15(8-12)28-10-27-14/h2-3,5-6,8,11,13H,4,7,9-10H2,1H3,(H,19,20)(H,21,22)(H,23,24)(H,25,26)/t11-,13?/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 9.50E+4n/an/an/an/an/an/a



SVIMS University



Assay Description
Inhibiton assay using MurgD.


Citation and Details
More data for this
Ligand-Target Pair
UDP-N-acetylmuramoylalanine--D-glutamate ligase (MurgD)


(Leptospira interrogans)
BDBM81617
PNG
(Benzene 1,3-dicarvboxylic acid inhibitor)
Show SMILES OC(=O)c1cc(cc(c1)-c1ccc(\C=C2/SC(=S)N(C2=O)c2ccc3OCOc3c2)o1)C(O)=O
Show InChI InChI=1S/C23H13NO8S2/c25-20-19(34-23(33)24(20)14-1-3-17-18(8-14)31-10-30-17)9-15-2-4-16(32-15)11-5-12(21(26)27)7-13(6-11)22(28)29/h1-9H,10H2,(H,26,27)(H,28,29)/b19-9-
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 2.70E+5n/an/an/an/an/an/a



SVIMS University



Assay Description
Inhibiton assay using MurgD.


Citation and Details
More data for this
Ligand-Target Pair