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Compile Data Set for Download or QSAR

Found 52 hits Enz. Inhib. hit(s) with Target = 'Urokinase plasminogen activator surface receptor' AND taxid = 9606   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Urokinase plasminogen activator surface receptor


(Homo sapiens)
BDBM50402366
PNG
(CHEMBL2206696)
Show SMILES Nc1c(cc(-c2ccccc2)n1-c1ccncc1)-c1nc2ccccc2[nH]1
Show InChI InChI=1S/C22H17N5/c23-21-17(22-25-18-8-4-5-9-19(18)26-22)14-20(15-6-2-1-3-7-15)27(21)16-10-12-24-13-11-16/h1-14H,23H2,(H,25,26)
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1n/an/an/an/an/an/an/an/a



National Research Center

Curated by ChEMBL


Assay Description
Binding affinity to uPAR


Citation and Details
More data for this
Ligand-Target Pair
Urokinase plasminogen activator surface receptor


(Homo sapiens)
BDBM50402364
PNG
(CHEMBL2206698)
Show SMILES Nc1c(cc(-c2ccccc2)n1-c1ccc(Br)cc1)-c1nc2ccccc2[nH]1
Show InChI InChI=1S/C23H17BrN4/c24-16-10-12-17(13-11-16)28-21(15-6-2-1-3-7-15)14-18(22(28)25)23-26-19-8-4-5-9-20(19)27-23/h1-14H,25H2,(H,26,27)
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1.10n/an/an/an/an/an/an/an/a



National Research Center

Curated by ChEMBL


Assay Description
Binding affinity to uPAR


Citation and Details
More data for this
Ligand-Target Pair
Urokinase plasminogen activator surface receptor


(Homo sapiens)
BDBM50402365
PNG
(CHEMBL2206697)
Show SMILES Nc1c(cc(-c2ccccc2)n1-c1cccc(Br)c1)-c1nc2ccccc2[nH]1
Show InChI InChI=1S/C23H17BrN4/c24-16-9-6-10-17(13-16)28-21(15-7-2-1-3-8-15)14-18(22(28)25)23-26-19-11-4-5-12-20(19)27-23/h1-14H,25H2,(H,26,27)
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1.20n/an/an/an/an/an/an/an/a



National Research Center

Curated by ChEMBL


Assay Description
Binding affinity to uPAR


Citation and Details
More data for this
Ligand-Target Pair
Urokinase plasminogen activator surface receptor


(Homo sapiens)
BDBM50402368
PNG
(CHEMBL2206682)
Show SMILES O=C1NC2=Nc3ccccc3NC2=Nc2ccccc12
Show InChI InChI=1S/C15H10N4O/c20-15-9-5-1-2-6-10(9)16-13-14(19-15)18-12-8-4-3-7-11(12)17-13/h1-8H,(H,16,17)(H,18,19,20)
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1.30n/an/an/an/an/an/an/an/a



National Research Center

Curated by ChEMBL


Assay Description
Binding affinity to uPAR


Citation and Details
More data for this
Ligand-Target Pair
Urokinase plasminogen activator surface receptor


(Homo sapiens)
BDBM50402361
PNG
(CHEMBL2206680)
Show SMILES Nc1c(cc(-c2ccccc2)n1-c1nc2ccccc2[nH]1)-c1nc2ccccc2[nH]1
Show InChI InChI=1S/C24H18N6/c25-22-16(23-26-17-10-4-5-11-18(17)27-23)14-21(15-8-2-1-3-9-15)30(22)24-28-19-12-6-7-13-20(19)29-24/h1-14H,25H2,(H,26,27)(H,28,29)
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1.5n/an/an/an/an/an/an/an/a



National Research Center

Curated by ChEMBL


Assay Description
Binding affinity to uPAR


Citation and Details
More data for this
Ligand-Target Pair
Urokinase plasminogen activator surface receptor


(Homo sapiens)
BDBM50402378
PNG
(CHEMBL2206685)
Show SMILES CCOC(=O)Cn1c(CN2C3=Nc4ccccc4C(=O)NC3=Nc3ccccc23)nc2ccccc12
Show InChI InChI=1S/C27H22N6O3/c1-2-36-24(34)16-32-21-13-7-5-11-19(21)28-23(32)15-33-22-14-8-6-12-20(22)29-25-26(33)30-18-10-4-3-9-17(18)27(35)31-25/h3-14H,2,15-16H2,1H3,(H,29,31,35)
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1.70n/an/an/an/an/an/an/an/a



National Research Center

Curated by ChEMBL


Assay Description
Binding affinity to uPAR


Citation and Details
More data for this
Ligand-Target Pair
Urokinase plasminogen activator surface receptor


(Homo sapiens)
BDBM50402369
PNG
(CHEMBL1652555)
Show SMILES Nc1nc2ccccc2[nH]c1=O
Show InChI InChI=1S/C8H7N3O/c9-7-8(12)11-6-4-2-1-3-5(6)10-7/h1-4H,(H2,9,10)(H,11,12)
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2.10n/an/an/an/an/an/an/an/a



National Research Center

Curated by ChEMBL


Assay Description
Binding affinity to uPAR


Citation and Details
More data for this
Ligand-Target Pair
Urokinase plasminogen activator surface receptor


(Homo sapiens)
BDBM50402360
PNG
(CHEMBL2206681)
Show SMILES Nc1c(cc(-c2ccccc2)n1Cc1nc2ccccc2[nH]1)-c1nc2ccccc2[nH]1
Show InChI InChI=1S/C25H20N6/c26-24-17(25-29-20-12-6-7-13-21(20)30-25)14-22(16-8-2-1-3-9-16)31(24)15-23-27-18-10-4-5-11-19(18)28-23/h1-14H,15,26H2,(H,27,28)(H,29,30)
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2.20n/an/an/an/an/an/an/an/a



National Research Center

Curated by ChEMBL


Assay Description
Binding affinity to uPAR


Citation and Details
More data for this
Ligand-Target Pair
Urokinase plasminogen activator surface receptor


(Homo sapiens)
BDBM50402373
PNG
(CHEMBL2206691)
Show SMILES Nc1c(cc(-c2ccccc2)n1-c1cccc(Cl)c1)C#N
Show InChI InChI=1S/C17H12ClN3/c18-14-7-4-8-15(10-14)21-16(9-13(11-19)17(21)20)12-5-2-1-3-6-12/h1-10H,20H2
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2.30n/an/an/an/an/an/an/an/a



National Research Center

Curated by ChEMBL


Assay Description
Binding affinity to uPAR


Citation and Details
More data for this
Ligand-Target Pair
Urokinase plasminogen activator surface receptor


(Homo sapiens)
BDBM50005397
PNG
(CHEMBL2206684)
Show SMILES C=CCn1c(CN2C3=Nc4ccccc4C(=O)NC3=Nc3ccccc23)nc2ccccc12
Show InChI InChI=1S/C26H20N6O/c1-2-15-31-21-13-7-5-11-19(21)27-23(31)16-32-22-14-8-6-12-20(22)28-24-25(32)29-18-10-4-3-9-17(18)26(33)30-24/h2-14H,1,15-16H2,(H,28,30,33)
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2.90n/an/an/an/an/an/an/an/a



National Research Center

Curated by ChEMBL


Assay Description
Binding affinity to uPAR


Citation and Details
More data for this
Ligand-Target Pair
Urokinase plasminogen activator surface receptor


(Homo sapiens)
BDBM50402371
PNG
(CHEMBL2206693)
Show SMILES Nc1c(cc(-c2ccccc2)n1-c1nc2ccccc2[nH]1)C#N
Show InChI InChI=1S/C18H13N5/c19-11-13-10-16(12-6-2-1-3-7-12)23(17(13)20)18-21-14-8-4-5-9-15(14)22-18/h1-10H,20H2,(H,21,22)
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3n/an/an/an/an/an/an/an/a



National Research Center

Curated by ChEMBL


Assay Description
Binding affinity to uPAR


Citation and Details
More data for this
Ligand-Target Pair
Urokinase plasminogen activator surface receptor


(Homo sapiens)
BDBM50402379
PNG
(CHEMBL2206686)
Show SMILES O=C(CC(C#N)C#N)c1ccccc1
Show InChI InChI=1S/C11H8N2O/c12-7-9(8-13)6-11(14)10-4-2-1-3-5-10/h1-5,9H,6H2
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3n/an/an/an/an/an/an/an/a



National Research Center

Curated by ChEMBL


Assay Description
Binding affinity to uPAR


Citation and Details
More data for this
Ligand-Target Pair
Urokinase plasminogen activator surface receptor


(Homo sapiens)
BDBM50402377
PNG
(CHEMBL2206687)
Show SMILES Nc1c(cc(-c2ccccc2)n1-c1ccccn1)C#N
Show InChI InChI=1S/C16H12N4/c17-11-13-10-14(12-6-2-1-3-7-12)20(16(13)18)15-8-4-5-9-19-15/h1-10H,18H2
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3.30n/an/an/an/an/an/an/an/a



National Research Center

Curated by ChEMBL


Assay Description
Binding affinity to uPAR


Citation and Details
More data for this
Ligand-Target Pair
Urokinase plasminogen activator surface receptor


(Homo sapiens)
BDBM50402374
PNG
(CHEMBL2206690)
Show SMILES Nc1c(cc(-c2ccccc2)n1-c1ccc(Br)cc1)C#N
Show InChI InChI=1S/C17H12BrN3/c18-14-6-8-15(9-7-14)21-16(10-13(11-19)17(21)20)12-4-2-1-3-5-12/h1-10H,20H2
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3.30n/an/an/an/an/an/an/an/a



National Research Center

Curated by ChEMBL


Assay Description
Binding affinity to uPAR


Citation and Details
More data for this
Ligand-Target Pair
Urokinase plasminogen activator surface receptor


(Homo sapiens)
BDBM50402372
PNG
(CHEMBL2206692)
Show SMILES Nc1c(cc(-c2ccccc2)n1-c1ccc(Cl)cc1)C#N
Show InChI InChI=1S/C17H12ClN3/c18-14-6-8-15(9-7-14)21-16(10-13(11-19)17(21)20)12-4-2-1-3-5-12/h1-10H,20H2
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3.30n/an/an/an/an/an/an/an/a



National Research Center

Curated by ChEMBL


Assay Description
Binding affinity to uPAR


Citation and Details
More data for this
Ligand-Target Pair
Urokinase plasminogen activator surface receptor


(Homo sapiens)
BDBM50402375
PNG
(CHEMBL2206689)
Show SMILES Nc1c(cc(-c2ccccc2)n1-c1cccc(Br)c1)C#N
Show InChI InChI=1S/C17H12BrN3/c18-14-7-4-8-15(10-14)21-16(9-13(11-19)17(21)20)12-5-2-1-3-6-12/h1-10H,20H2
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4.10n/an/an/an/an/an/an/an/a



National Research Center

Curated by ChEMBL


Assay Description
Binding affinity to uPAR


Citation and Details
More data for this
Ligand-Target Pair
Urokinase plasminogen activator surface receptor


(Homo sapiens)
BDBM50402363
PNG
(CHEMBL2206699)
Show SMILES Nc1c(cc(-c2ccccc2)n1-c1cccc(Cl)c1)-c1nc2ccccc2[nH]1
Show InChI InChI=1S/C23H17ClN4/c24-16-9-6-10-17(13-16)28-21(15-7-2-1-3-8-15)14-18(22(28)25)23-26-19-11-4-5-12-20(19)27-23/h1-14H,25H2,(H,26,27)
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4.40n/an/an/an/an/an/an/an/a



National Research Center

Curated by ChEMBL


Assay Description
Binding affinity to uPAR


Citation and Details
More data for this
Ligand-Target Pair
Urokinase plasminogen activator surface receptor


(Homo sapiens)
BDBM50402362
PNG
(CHEMBL2206700)
Show SMILES Nc1c(cc(-c2ccccc2)n1-c1ccc(Cl)cc1)-c1nc2ccccc2[nH]1
Show InChI InChI=1S/C23H17ClN4/c24-16-10-12-17(13-11-16)28-21(15-6-2-1-3-7-15)14-18(22(28)25)23-26-19-8-4-5-9-20(19)27-23/h1-14H,25H2,(H,26,27)
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4.5n/an/an/an/an/an/an/an/a



National Research Center

Curated by ChEMBL


Assay Description
Binding affinity to uPAR


Citation and Details
More data for this
Ligand-Target Pair
Urokinase plasminogen activator surface receptor


(Homo sapiens)
BDBM50005398
PNG
(CHEMBL2206694)
Show SMILES Nc1c(cc(-c2ccccc2)n1Cc1nc2ccccc2[nH]1)C#N
Show InChI InChI=1S/C19H15N5/c20-11-14-10-17(13-6-2-1-3-7-13)24(19(14)21)12-18-22-15-8-4-5-9-16(15)23-18/h1-10H,12,21H2,(H,22,23)
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5.90n/an/an/an/an/an/an/an/a



National Research Center

Curated by ChEMBL


Assay Description
Binding affinity to uPAR


Citation and Details
More data for this
Ligand-Target Pair
Urokinase plasminogen activator surface receptor


(Homo sapiens)
BDBM50402370
PNG
(CHEMBL2206683)
Show SMILES O=C1NC2=Nc3ccccc3N(Cc3nc4ccccc4[nH]3)C2=Nc2ccccc12
Show InChI InChI=1S/C23H16N6O/c30-23-14-7-1-2-8-15(14)27-22-21(28-23)26-18-11-5-6-12-19(18)29(22)13-20-24-16-9-3-4-10-17(16)25-20/h1-12H,13H2,(H,24,25)(H,26,28,30)
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6.40n/an/an/an/an/an/an/an/a



National Research Center

Curated by ChEMBL


Assay Description
Binding affinity to uPAR


Citation and Details
More data for this
Ligand-Target Pair
Urokinase plasminogen activator surface receptor


(Homo sapiens)
BDBM50402367
PNG
(CHEMBL2206695)
Show SMILES Nc1c(cc(-c2ccccc2)n1-c1ccccn1)-c1nc2ccccc2[nH]1
Show InChI InChI=1S/C22H17N5/c23-21-16(22-25-17-10-4-5-11-18(17)26-22)14-19(15-8-2-1-3-9-15)27(21)20-12-6-7-13-24-20/h1-14H,23H2,(H,25,26)
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6.5n/an/an/an/an/an/an/an/a



National Research Center

Curated by ChEMBL


Assay Description
Binding affinity to uPAR


Citation and Details
More data for this
Ligand-Target Pair
Urokinase plasminogen activator surface receptor


(Homo sapiens)
BDBM50402376
PNG
(CHEMBL2206688)
Show SMILES Nc1c(cc(-c2ccccc2)n1-c1ccncc1)C#N
Show InChI InChI=1S/C16H12N4/c17-11-13-10-15(12-4-2-1-3-5-12)20(16(13)18)14-6-8-19-9-7-14/h1-10H,18H2
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7.60n/an/an/an/an/an/an/an/a



National Research Center

Curated by ChEMBL


Assay Description
Binding affinity to uPAR


Citation and Details
More data for this
Ligand-Target Pair
Urokinase plasminogen activator surface receptor


(Homo sapiens)
BDBM50357760
PNG
(CHEMBL1916397)
Show SMILES CN(C)c1ccc(CNCCC(Cc2ccccc2)c2ccc3OCOc3c2)cc1
Show InChI InChI=1S/C26H30N2O2/c1-28(2)24-11-8-21(9-12-24)18-27-15-14-23(16-20-6-4-3-5-7-20)22-10-13-25-26(17-22)30-19-29-25/h3-13,17,23,27H,14-16,18-19H2,1-2H3
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2.00E+4n/an/an/an/an/an/an/an/a



Indiana University School of Medicine

Curated by ChEMBL


Assay Description
Displacement of AE417-FAM peptide from human uPAR expressed in drosophila S2 cells by fluorescence polarization assay


Citation and Details
More data for this
Ligand-Target Pair
Urokinase plasminogen activator surface receptor


(Homo sapiens)
BDBM50421510
PNG
(CHEMBL239127)
Show SMILES CC[C@H](C)[C@@H]1NC(=O)[C@@H]2CCCN2C(=O)[C@@H]2CCCN2C(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H]2CSSC[C@H](NC1=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N1CCC[C@@H]1C(=O)N[C@@H](CC(O)=O)C(=O)NCC(=O)N[C@@H](CCCN=C(N)N)C(=O)N2)[C@@H](C)O)[C@@H](C)CC
Show InChI InChI=1S/C67H104N18O18S2/c1-6-35(3)51-62(99)79-44-33-104-105-34-45(78-55(92)39(20-13-25-71-67(69)70)73-49(88)31-72-54(91)41(30-50(89)90)75-60(97)46-21-14-26-83(46)64(101)42(76-58(44)95)29-38-17-9-8-10-18-38)59(96)82-53(37(5)87)63(100)74-40(19-11-12-24-68)56(93)77-43(32-86)57(94)81-52(36(4)7-2)66(103)85-28-16-23-48(85)65(102)84-27-15-22-47(84)61(98)80-51/h8-10,17-18,35-37,39-48,51-53,86-87H,6-7,11-16,19-34,68H2,1-5H3,(H,72,91)(H,73,88)(H,74,100)(H,75,97)(H,76,95)(H,77,93)(H,78,92)(H,79,99)(H,80,98)(H,81,94)(H,82,96)(H,89,90)(H4,69,70,71)/t35-,36-,37+,39-,40-,41-,42-,43-,44-,45-,46+,47-,48-,51-,52-,53-/m0/s1
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5.00E+5n/an/an/an/an/an/an/an/a



National Cancer Institute

Curated by ChEMBL


Assay Description
Compound was tested for microPa) Urokinase-type plasminogen activator from human urine


Bioorg Med Chem Lett 11: 2515-9 (2001)

More data for this
Ligand-Target Pair
Urokinase plasminogen activator surface receptor


(Homo sapiens)
BDBM50120747
PNG
(CHEMBL412236 | cyclic uPA-derived peptide)
Show SMILES CC(C)C[C@H]1NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](CC(N)=O)NC(=O)[C@@H](N)CSSC[C@H](NC(=O)[C@H]2CCCN2C(=O)[C@@H](NC(=O)[C@@H](CCC(N)=O)NC(=O)[C@H](Cc2cnc[nH]2)NC1=O)C(C)C)C(=O)N[C@@H](CC(N)=O)C(O)=O
Show InChI InChI=1S/C46H71N15O16S2/c1-20(2)12-26-40(70)57-27(13-22-16-51-19-52-22)41(71)53-24(7-9-32(48)62)39(69)60-36(21(3)4)45(75)61-11-5-6-31(61)44(74)59-30(43(73)58-29(46(76)77)15-34(50)64)18-79-78-17-23(47)37(67)55-28(14-33(49)63)42(72)54-25(38(68)56-26)8-10-35(65)66/h16,19-21,23-31,36H,5-15,17-18,47H2,1-4H3,(H2,48,62)(H2,49,63)(H2,50,64)(H,51,52)(H,53,71)(H,54,72)(H,55,67)(H,56,68)(H,57,70)(H,58,73)(H,59,74)(H,60,69)(H,65,66)(H,76,77)/t23-,24+,25-,26+,27-,28+,29-,30-,31+,36-/m0/s1
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n/an/a 40n/an/an/an/an/an/a



Technische Universität München

Curated by ChEMBL


Assay Description
Inhibitory activity of the compound against human Urokinase plasminogen activator receptor (uPAR) was determined


J Med Chem 45: 4984-94 (2002)

More data for this
Ligand-Target Pair
Urokinase plasminogen activator surface receptor


(Homo sapiens)
BDBM50120746
PNG
(CHEMBL405302 | cyclic uPA-derived peptide)
Show SMILES CC(C)[C@@H]1NC(=O)[C@@H](CCC(N)=O)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@@H](Cc2cccc3ccccc23)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](CC(N)=O)NC(=O)[C@@H](N)CSSC[C@H](NC(=O)[C@H]2CCCN2C1=O)C(=O)N[C@@H](CC(N)=O)C(O)=O
Show InChI InChI=1S/C53H71N15O16S2/c1-25(2)43-52(82)68-16-6-11-38(68)51(81)66-37(50(80)65-36(53(83)84)20-41(57)71)23-86-85-22-30(54)44(74)62-35(19-40(56)70)49(79)61-32(13-15-42(72)73)45(75)63-33(17-27-9-5-8-26-7-3-4-10-29(26)27)47(77)64-34(18-28-21-58-24-59-28)48(78)60-31(46(76)67-43)12-14-39(55)69/h3-5,7-10,21,24-25,30-38,43H,6,11-20,22-23,54H2,1-2H3,(H2,55,69)(H2,56,70)(H2,57,71)(H,58,59)(H,60,78)(H,61,79)(H,62,74)(H,63,75)(H,64,77)(H,65,80)(H,66,81)(H,67,76)(H,72,73)(H,83,84)/t30-,31+,32-,33+,34-,35+,36-,37-,38+,43-/m0/s1
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n/an/a 50n/an/an/an/an/an/a



Technische Universität München

Curated by ChEMBL


Assay Description
Inhibitory activity of the compound against human Urokinase plasminogen activator receptor (uPAR) was determined


J Med Chem 45: 4984-94 (2002)

More data for this
Ligand-Target Pair
Urokinase plasminogen activator surface receptor


(Homo sapiens)
BDBM50120740
PNG
(CHEMBL405999 | cyclic uPA-derived peptide)
Show SMILES CCCC[C@@H]1NC(=O)[C@@H](CC(N)=O)NC(=O)[C@@H](N)CSSC[C@H](NC(=O)[C@H]2CCCN2C(=O)[C@@H](NC(=O)[C@@H](CCC(N)=O)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@@H](CC(C)C)NC1=O)C(C)C)C(=O)N[C@@H](CC(N)=O)C(O)=O
Show InChI InChI=1S/C47H75N15O14S2/c1-6-7-9-26-39(67)57-28(14-22(2)3)41(69)58-29(15-24-18-52-21-53-24)42(70)55-27(11-12-34(49)63)40(68)61-37(23(4)5)46(74)62-13-8-10-33(62)45(73)60-32(44(72)59-31(47(75)76)17-36(51)65)20-78-77-19-25(48)38(66)56-30(16-35(50)64)43(71)54-26/h18,21-23,25-33,37H,6-17,19-20,48H2,1-5H3,(H2,49,63)(H2,50,64)(H2,51,65)(H,52,53)(H,54,71)(H,55,70)(H,56,66)(H,57,67)(H,58,69)(H,59,72)(H,60,73)(H,61,68)(H,75,76)/t25-,26-,27+,28+,29-,30+,31-,32-,33+,37-/m0/s1
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n/an/a 60n/an/an/an/an/an/a



Technische Universität München

Curated by ChEMBL


Assay Description
Inhibitory activity of the compound against human Urokinase plasminogen activator receptor (uPAR) was determined


J Med Chem 45: 4984-94 (2002)

More data for this
Ligand-Target Pair
Urokinase plasminogen activator surface receptor


(Homo sapiens)
BDBM50120745
PNG
(CHEMBL263158 | cyclic uPA-derived peptide)
Show SMILES CC(C)[C@@H]1NC(=O)[C@@H](CCC(N)=O)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@@H](Cc2ccc3ccccc3c2)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](CC(N)=O)NC(=O)[C@@H](N)CSSC[C@H](NC(=O)[C@H]2CCCN2C1=O)C(=O)N[C@@H](CC(N)=O)C(O)=O
Show InChI InChI=1S/C53H71N15O16S2/c1-25(2)43-52(82)68-15-5-8-38(68)51(81)66-37(50(80)65-36(53(83)84)20-41(57)71)23-86-85-22-30(54)44(74)62-35(19-40(56)70)49(79)61-32(12-14-42(72)73)45(75)63-33(17-26-9-10-27-6-3-4-7-28(27)16-26)47(77)64-34(18-29-21-58-24-59-29)48(78)60-31(46(76)67-43)11-13-39(55)69/h3-4,6-7,9-10,16,21,24-25,30-38,43H,5,8,11-15,17-20,22-23,54H2,1-2H3,(H2,55,69)(H2,56,70)(H2,57,71)(H,58,59)(H,60,78)(H,61,79)(H,62,74)(H,63,75)(H,64,77)(H,65,80)(H,66,81)(H,67,76)(H,72,73)(H,83,84)/t30-,31+,32-,33+,34-,35+,36-,37-,38+,43-/m0/s1
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n/an/a 80n/an/an/an/an/an/a



Technische Universität München

Curated by ChEMBL


Assay Description
Inhibitory activity of the compound against human Urokinase plasminogen activator receptor (uPAR) was determined


J Med Chem 45: 4984-94 (2002)

More data for this
Ligand-Target Pair
Urokinase plasminogen activator surface receptor


(Homo sapiens)
BDBM50120743
PNG
(CHEMBL385968 | cyclic uPA-derived peptide)
Show SMILES CC(C)C[C@H]1NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](CC(N)=O)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@@H](N)CSSC[C@@H](NC(=O)[C@@H](CC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H]2CCCN2C(=O)[C@@H](NC(=O)[C@@H](CCC(N)=O)NC(=O)[C@H](Cc2cnc[nH]2)NC1=O)C(C)C)C(O)=O
Show InChI InChI=1S/C54H84N18O21S2/c1-23(2)12-29-46(84)66-30(13-25-16-59-22-61-25)47(85)63-27(7-9-37(56)75)45(83)71-42(24(3)4)53(91)72-11-5-6-36(72)52(90)69-34(19-74)51(89)68-32(15-39(58)77)49(87)70-35(54(92)93)21-95-94-20-26(55)43(81)60-17-40(78)62-33(18-73)50(88)67-31(14-38(57)76)48(86)64-28(44(82)65-29)8-10-41(79)80/h16,22-24,26-36,42,73-74H,5-15,17-21,55H2,1-4H3,(H2,56,75)(H2,57,76)(H2,58,77)(H,59,61)(H,60,81)(H,62,78)(H,63,85)(H,64,86)(H,65,82)(H,66,84)(H,67,88)(H,68,89)(H,69,90)(H,70,87)(H,71,83)(H,79,80)(H,92,93)/t26-,27+,28-,29+,30-,31+,32+,33-,34-,35+,36+,42-/m0/s1
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n/an/a 200n/an/an/an/an/an/a



Technische Universität München

Curated by ChEMBL


Assay Description
Inhibitory activity of the compound against human Urokinase plasminogen activator receptor (uPAR) was determined


J Med Chem 45: 4984-94 (2002)

More data for this
Ligand-Target Pair
Urokinase plasminogen activator surface receptor


(Homo sapiens)
BDBM50120749
PNG
(CHEMBL412223 | cyclic uPA-derived peptide)
Show SMILES CC(C)C[C@H]1NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](CC(N)=O)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](N)CSSC[C@@H](NC(=O)[C@@H](CC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H]2CCCN2C(=O)[C@@H](NC(=O)[C@@H](CCC(N)=O)NC(=O)[C@H](Cc2cnc[nH]2)NC1=O)C(C)C)C(O)=O
Show InChI InChI=1S/C54H84N18O21S2/c1-23(2)12-29-46(84)66-30(13-25-16-59-22-61-25)47(85)63-27(7-9-37(56)75)45(83)71-42(24(3)4)53(91)72-11-5-6-36(72)52(90)69-34(19-74)51(89)68-32(15-39(58)77)49(87)70-35(54(92)93)21-95-94-20-26(55)43(81)60-17-40(78)62-33(18-73)50(88)67-31(14-38(57)76)48(86)64-28(44(82)65-29)8-10-41(79)80/h16,22-24,26-36,42,73-74H,5-15,17-21,55H2,1-4H3,(H2,56,75)(H2,57,76)(H2,58,77)(H,59,61)(H,60,81)(H,62,78)(H,63,85)(H,64,86)(H,65,82)(H,66,84)(H,67,88)(H,68,89)(H,69,90)(H,70,87)(H,71,83)(H,79,80)(H,92,93)/t26-,27-,28+,29-,30+,31-,32-,33+,34+,35-,36-,42+/m1/s1
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n/an/a 700n/an/an/an/an/an/a



Technische Universität München

Curated by ChEMBL


Assay Description
Inhibitory activity of the compound against human Urokinase plasminogen activator receptor (uPAR) was determined


J Med Chem 45: 4984-94 (2002)

More data for this
Ligand-Target Pair
Urokinase plasminogen activator surface receptor


(Homo sapiens)
BDBM50120742
PNG
(CHEMBL264653 | cyclic uPA-derived peptide)
Show SMILES CC(C)C[C@H]1NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](CC(N)=O)NC(=O)[C@H](N)CSSC[C@@H](NC(=O)[C@H]2CCCN2C(=O)[C@@H](NC(=O)[C@@H](CCC(N)=O)NC(=O)[C@H](Cc2cnc[nH]2)NC1=O)C(C)C)C(=O)N[C@@H](CC(N)=O)C(O)=O
Show InChI InChI=1S/C46H71N15O16S2/c1-20(2)12-26-40(70)57-27(13-22-16-51-19-52-22)41(71)53-24(7-9-32(48)62)39(69)60-36(21(3)4)45(75)61-11-5-6-31(61)44(74)59-30(43(73)58-29(46(76)77)15-34(50)64)18-79-78-17-23(47)37(67)55-28(14-33(49)63)42(72)54-25(38(68)56-26)8-10-35(65)66/h16,19-21,23-31,36H,5-15,17-18,47H2,1-4H3,(H2,48,62)(H2,49,63)(H2,50,64)(H,51,52)(H,53,71)(H,54,72)(H,55,67)(H,56,68)(H,57,70)(H,58,73)(H,59,74)(H,60,69)(H,65,66)(H,76,77)/t23-,24-,25+,26-,27+,28-,29+,30-,31-,36+/m1/s1
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n/an/a 900n/an/an/an/an/an/a



Technische Universität München

Curated by ChEMBL


Assay Description
Inhibitory activity of the compound against human Urokinase plasminogen activator receptor (uPAR) was determined


J Med Chem 45: 4984-94 (2002)

More data for this
Ligand-Target Pair
Urokinase plasminogen activator surface receptor


(Homo sapiens)
BDBM50401180
PNG
(CHEMBL2206354)
Show SMILES CC1CC(C)CN(C1)c1cc(Nc2cccc(c2)C(O)=O)c2C(=O)c3ccccc3-c3onc1c23
Show InChI InChI=1S/C28H25N3O4/c1-15-10-16(2)14-31(13-15)22-12-21(29-18-7-5-6-17(11-18)28(33)34)23-24-25(22)30-35-27(24)20-9-4-3-8-19(20)26(23)32/h3-9,11-12,15-16,29H,10,13-14H2,1-2H3,(H,33,34)
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n/an/a 5.00E+3n/an/an/an/an/an/a



Indiana University

Curated by ChEMBL


Assay Description
Inhibition of urokinase receptor binding to uPA amino terminal fragment by ELISA


Citation and Details
More data for this
Ligand-Target Pair
Urokinase plasminogen activator surface receptor


(Homo sapiens)
BDBM50401189
PNG
(CHEMBL2205795)
Show SMILES CC1CCCN(C1)c1cc(Nc2cccc(c2)C(O)=O)c2C(=O)c3ccccc3-c3onc1c23
Show InChI InChI=1S/C27H23N3O4/c1-15-6-5-11-30(14-15)21-13-20(28-17-8-4-7-16(12-17)27(32)33)22-23-24(21)29-34-26(23)19-10-3-2-9-18(19)25(22)31/h2-4,7-10,12-13,15,28H,5-6,11,14H2,1H3,(H,32,33)
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n/an/a 7.00E+3n/an/an/an/an/an/a



Indiana University

Curated by ChEMBL


Assay Description
Inhibition of urokinase receptor binding to uPA amino terminal fragment by ELISA


Citation and Details
More data for this
Ligand-Target Pair
Urokinase plasminogen activator surface receptor


(Homo sapiens)
BDBM50401187
PNG
(CHEMBL2205797)
Show SMILES CC1CCCCN1c1cc(Nc2cccc(c2)C(O)=O)c2C(=O)c3ccccc3-c3onc1c23
Show InChI InChI=1S/C27H23N3O4/c1-15-7-4-5-12-30(15)21-14-20(28-17-9-6-8-16(13-17)27(32)33)22-23-24(21)29-34-26(23)19-11-3-2-10-18(19)25(22)31/h2-3,6,8-11,13-15,28H,4-5,7,12H2,1H3,(H,32,33)
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n/an/a 1.00E+4n/an/an/an/an/an/a



Indiana University

Curated by ChEMBL


Assay Description
Inhibition of urokinase receptor binding to uPA amino terminal fragment by ELISA


Citation and Details
More data for this
Ligand-Target Pair
Urokinase plasminogen activator surface receptor


(Homo sapiens)
BDBM50401178
PNG
(CHEMBL2206358)
Show SMILES CC1CC(C)CN(C1)c1cc(Nc2ccccc2C(O)=O)c2C(=O)c3ccccc3-c3onc1c23
Show InChI InChI=1S/C28H25N3O4/c1-15-11-16(2)14-31(13-15)22-12-21(29-20-10-6-5-9-19(20)28(33)34)23-24-25(22)30-35-27(24)18-8-4-3-7-17(18)26(23)32/h3-10,12,15-16,29H,11,13-14H2,1-2H3,(H,33,34)
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n/an/a 1.00E+4n/an/an/an/an/an/a



Indiana University

Curated by ChEMBL


Assay Description
Inhibition of urokinase receptor binding to uPA amino terminal fragment by ELISA


Citation and Details
More data for this
Ligand-Target Pair
Urokinase plasminogen activator surface receptor


(Homo sapiens)
BDBM50401188
PNG
(CHEMBL2205796)
Show SMILES CC1CCCN(C1)c1cc(=Cc2ccc(cc2)C(O)=O)c2c(O)c3ccccc3c3onc1c23
Show InChI InChI=1S/C28H24N2O4/c1-16-5-4-12-30(15-16)22-14-19(13-17-8-10-18(11-9-17)28(32)33)23-24-25(22)29-34-27(24)21-7-3-2-6-20(21)26(23)31/h2-3,6-11,13-14,16,31H,4-5,12,15H2,1H3,(H,32,33)
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n/an/a 1.10E+4n/an/an/an/an/an/a



Indiana University

Curated by ChEMBL


Assay Description
Inhibition of urokinase receptor binding to uPA amino terminal fragment by ELISA


Citation and Details
More data for this
Ligand-Target Pair
Urokinase plasminogen activator surface receptor


(Homo sapiens)
BDBM50401186
PNG
(CHEMBL2206348)
Show SMILES CC1CC(C)CN(C1)c1cc(NCCC(O)=O)c2C(=O)c3ccccc3-c3onc1c23
Show InChI InChI=1S/C24H25N3O4/c1-13-9-14(2)12-27(11-13)18-10-17(25-8-7-19(28)29)20-21-22(18)26-31-24(21)16-6-4-3-5-15(16)23(20)30/h3-6,10,13-14,25H,7-9,11-12H2,1-2H3,(H,28,29)
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n/an/a 1.80E+4n/an/an/an/an/an/a



Indiana University

Curated by ChEMBL


Assay Description
Inhibition of urokinase receptor binding to uPA amino terminal fragment by ELISA


Citation and Details
More data for this
Ligand-Target Pair
Urokinase plasminogen activator surface receptor


(Homo sapiens)
BDBM50401181
PNG
(CHEMBL2206353)
Show SMILES CC1CCCN(C1)c1cc(NCCCC(O)=O)c2C(=O)c3ccccc3-c3onc1c23
Show InChI InChI=1S/C24H25N3O4/c1-14-6-5-11-27(13-14)18-12-17(25-10-4-9-19(28)29)20-21-22(18)26-31-24(21)16-8-3-2-7-15(16)23(20)30/h2-3,7-8,12,14,25H,4-6,9-11,13H2,1H3,(H,28,29)
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PubMed
n/an/a 2.00E+4n/an/an/an/an/an/a



Indiana University

Curated by ChEMBL


Assay Description
Inhibition of urokinase receptor binding to uPA amino terminal fragment by ELISA


Citation and Details
More data for this
Ligand-Target Pair
Urokinase plasminogen activator surface receptor


(Homo sapiens)
BDBM50401190
PNG
(CHEMBL2205794)
Show SMILES OC(=O)c1ccccc1Nc1cc(N2CCCC2)c2noc3-c4ccccc4C(=O)c1c23
Show InChI InChI=1S/C25H19N3O4/c29-23-14-7-1-2-8-15(14)24-21-20(23)18(26-17-10-4-3-9-16(17)25(30)31)13-19(22(21)27-32-24)28-11-5-6-12-28/h1-4,7-10,13,26H,5-6,11-12H2,(H,30,31)
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n/an/a 2.10E+4n/an/an/an/an/an/a



Indiana University

Curated by ChEMBL


Assay Description
Inhibition of urokinase receptor binding to uPA amino terminal fragment by ELISA


Citation and Details
More data for this
Ligand-Target Pair
Urokinase plasminogen activator surface receptor


(Homo sapiens)
BDBM50401184
PNG
(CHEMBL2206350)
Show SMILES CC1CCCN(C1)c1cc(NCCC(O)=O)c2C(=O)c3ccccc3-c3onc1c23
Show InChI InChI=1S/C23H23N3O4/c1-13-5-4-10-26(12-13)17-11-16(24-9-8-18(27)28)19-20-21(17)25-30-23(20)15-7-3-2-6-14(15)22(19)29/h2-3,6-7,11,13,24H,4-5,8-10,12H2,1H3,(H,27,28)
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n/an/a 2.40E+4n/an/an/an/an/an/a



Indiana University

Curated by ChEMBL


Assay Description
Inhibition of urokinase receptor binding to uPA amino terminal fragment by ELISA


Citation and Details
More data for this
Ligand-Target Pair
Urokinase plasminogen activator surface receptor


(Homo sapiens)
BDBM50401174
PNG
(CHEMBL2206364)
Show SMILES CC(C)Oc1c(Br)cc(Nc2cccc(c2)C(O)=O)c2C(=O)c3ccccc3C(=O)c12
Show InChI InChI=1S/C24H18BrNO5/c1-12(2)31-23-17(25)11-18(26-14-7-5-6-13(10-14)24(29)30)19-20(23)22(28)16-9-4-3-8-15(16)21(19)27/h3-12,26H,1-2H3,(H,29,30)
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n/an/a 3.00E+4n/an/an/an/an/an/a



Indiana University

Curated by ChEMBL


Assay Description
Inhibition of urokinase receptor binding to uPA amino terminal fragment by ELISA


Citation and Details
More data for this
Ligand-Target Pair
Urokinase plasminogen activator surface receptor


(Homo sapiens)
BDBM50120748
PNG
(CHEMBL217327 | cyclic uPA-derived peptide)
Show SMILES CC(C)C[C@H]1NC(=O)[C@@H](CCCCN)NC(=O)[C@@H](CC(N)=O)NC(=O)[C@H](N)CSSC[C@@H](NC(=O)[C@H]2CCCN2C(=O)[C@@H](NC(=O)[C@@H](CCC(N)=O)NC(=O)[C@H](Cc2cnc[nH]2)NC1=O)C(C)C)C(=O)N[C@@H](CC(N)=O)C(O)=O
Show InChI InChI=1S/C47H76N16O14S2/c1-22(2)14-28-41(70)59-29(15-24-18-53-21-54-24)42(71)56-27(10-11-34(50)64)40(69)62-37(23(3)4)46(75)63-13-7-9-33(63)45(74)61-32(44(73)60-31(47(76)77)17-36(52)66)20-79-78-19-25(49)38(67)57-30(16-35(51)65)43(72)55-26(39(68)58-28)8-5-6-12-48/h18,21-23,25-33,37H,5-17,19-20,48-49H2,1-4H3,(H2,50,64)(H2,51,65)(H2,52,66)(H,53,54)(H,55,72)(H,56,71)(H,57,67)(H,58,68)(H,59,70)(H,60,73)(H,61,74)(H,62,69)(H,76,77)/t25-,26-,27-,28-,29+,30-,31+,32-,33-,37+/m1/s1
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n/an/a>3.00E+4n/an/an/an/an/an/a



Technische Universität München

Curated by ChEMBL


Assay Description
Inhibitory activity of the compound against human Urokinase plasminogen activator receptor (uPAR) was determined


J Med Chem 45: 4984-94 (2002)

More data for this
Ligand-Target Pair
Urokinase plasminogen activator surface receptor


(Homo sapiens)
BDBM50120750
PNG
(CHEMBL269566 | cyclic uPA-derived peptide)
Show SMILES CC(C)C[C@H]1NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](CC(N)=O)NC(=O)[C@H](N)CSSC[C@@H](NC(=O)[C@H]2CCCN2C(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](Cc2cnc[nH]2)NC1=O)C(C)C)C(=O)N[C@@H](CC(N)=O)C(O)=O
Show InChI InChI=1S/C44H68N14O16S2/c1-19(2)10-24-37(66)53-25(11-21-14-48-18-49-21)38(67)55-28(15-59)40(69)57-34(20(3)4)43(72)58-9-5-6-30(58)42(71)56-29(41(70)54-27(44(73)74)13-32(47)61)17-76-75-16-22(45)35(64)51-26(12-31(46)60)39(68)50-23(36(65)52-24)7-8-33(62)63/h14,18-20,22-30,34,59H,5-13,15-17,45H2,1-4H3,(H2,46,60)(H2,47,61)(H,48,49)(H,50,68)(H,51,64)(H,52,65)(H,53,66)(H,54,70)(H,55,67)(H,56,71)(H,57,69)(H,62,63)(H,73,74)/t22-,23+,24-,25+,26-,27+,28+,29-,30-,34+/m1/s1
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n/an/a>3.00E+4n/an/an/an/an/an/a



Technische Universität München

Curated by ChEMBL


Assay Description
Inhibitory activity of the compound against human Urokinase plasminogen activator receptor (uPAR) was determined


J Med Chem 45: 4984-94 (2002)

More data for this
Ligand-Target Pair
Urokinase plasminogen activator surface receptor


(Homo sapiens)
BDBM50401175
PNG
(CHEMBL2206363)
Show SMILES OC(=O)c1cccc(Nc2cc(Br)c(OCc3ccccc3)c3C(=O)c4ccccc4C(=O)c23)c1
Show InChI InChI=1S/C28H18BrNO5/c29-21-14-22(30-18-10-6-9-17(13-18)28(33)34)23-24(27(21)35-15-16-7-2-1-3-8-16)26(32)20-12-5-4-11-19(20)25(23)31/h1-14,30H,15H2,(H,33,34)
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n/an/a 3.00E+4n/an/an/an/an/an/a



Indiana University

Curated by ChEMBL


Assay Description
Inhibition of urokinase receptor binding to uPA amino terminal fragment by ELISA


Citation and Details
More data for this
Ligand-Target Pair
Urokinase plasminogen activator surface receptor


(Homo sapiens)
BDBM50120741
PNG
(CHEMBL437837 | cyclic uPA-derived peptide)
Show SMILES CC(C)C[C@H]1NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](CC(N)=O)NC(=O)[C@H](N)CSSC[C@@H](NC(=O)[C@H]2CCCN2C(=O)[C@H](CC(N)=O)NC(=O)[C@@H](CCC(N)=O)NC(=O)[C@H](Cc2cnc[nH]2)NC1=O)C(=O)N[C@@H](CC(N)=O)C(O)=O
Show InChI InChI=1S/C45H68N16O17S2/c1-19(2)10-24-39(71)57-25(11-20-15-51-18-52-20)40(72)53-22(5-7-31(47)62)38(70)58-27(13-33(49)64)44(76)61-9-3-4-30(61)43(75)60-29(42(74)59-28(45(77)78)14-34(50)65)17-80-79-16-21(46)36(68)55-26(12-32(48)63)41(73)54-23(37(69)56-24)6-8-35(66)67/h15,18-19,21-30H,3-14,16-17,46H2,1-2H3,(H2,47,62)(H2,48,63)(H2,49,64)(H2,50,65)(H,51,52)(H,53,72)(H,54,73)(H,55,68)(H,56,69)(H,57,71)(H,58,70)(H,59,74)(H,60,75)(H,66,67)(H,77,78)/t21-,22-,23+,24-,25+,26-,27+,28+,29-,30-/m1/s1
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n/an/a>3.00E+4n/an/an/an/an/an/a



Technische Universität München

Curated by ChEMBL


Assay Description
Inhibitory activity of the compound against human Urokinase plasminogen activator receptor (uPAR) was determined


J Med Chem 45: 4984-94 (2002)

More data for this
Ligand-Target Pair
Urokinase plasminogen activator surface receptor


(Homo sapiens)
BDBM50120744
PNG
(CHEMBL438371 | cyclic uPA-derived peptide)
Show SMILES CC(C)C[C@H]1NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](N)CSSC[C@@H](NC(=O)[C@H]2CCCN2C(=O)[C@@H](NC(=O)[C@@H](CCC(N)=O)NC(=O)[C@H](Cc2cnc[nH]2)NC1=O)C(C)C)C(=O)N[C@@H](CC(N)=O)C(O)=O
Show InChI InChI=1S/C46H71N15O16S2/c1-20(2)12-26-40(70)57-27(13-22-16-51-19-52-22)41(71)53-24(7-9-32(48)62)39(69)60-36(21(3)4)45(75)61-11-5-6-31(61)44(74)59-30(43(73)58-29(46(76)77)15-34(50)64)18-79-78-17-23(47)37(67)55-28(14-33(49)63)42(72)54-25(38(68)56-26)8-10-35(65)66/h16,19-21,23-31,36H,5-15,17-18,47H2,1-4H3,(H2,48,62)(H2,49,63)(H2,50,64)(H,51,52)(H,53,71)(H,54,72)(H,55,67)(H,56,68)(H,57,70)(H,58,73)(H,59,74)(H,60,69)(H,65,66)(H,76,77)/t23-,24-,25+,26-,27+,28+,29+,30-,31-,36+/m1/s1
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PubMed
n/an/a>3.00E+4n/an/an/an/an/an/a



Technische Universität München

Curated by ChEMBL


Assay Description
Inhibitory activity of the compound against human Urokinase plasminogen activator receptor (uPAR) was determined


J Med Chem 45: 4984-94 (2002)

More data for this
Ligand-Target Pair
Urokinase plasminogen activator surface receptor


(Homo sapiens)
BDBM50401185
PNG
(CHEMBL2206349)
Show SMILES CC1CC(C)CN(C1)c1cc(NCCCC(O)=O)c2C(=O)c3ccccc3-c3onc1c23
Show InChI InChI=1S/C25H27N3O4/c1-14-10-15(2)13-28(12-14)19-11-18(26-9-5-8-20(29)30)21-22-23(19)27-32-25(22)17-7-4-3-6-16(17)24(21)31/h3-4,6-7,11,14-15,26H,5,8-10,12-13H2,1-2H3,(H,29,30)
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PubMed
n/an/a 3.60E+4n/an/an/an/an/an/a



Indiana University

Curated by ChEMBL


Assay Description
Inhibition of urokinase receptor binding to uPA amino terminal fragment by ELISA


Citation and Details
More data for this
Ligand-Target Pair
Urokinase plasminogen activator surface receptor


(Homo sapiens)
BDBM50401183
PNG
(CHEMBL2206351)
Show SMILES CCOC(=O)C1CCCN(C1)c1cc(NCCC(O)=O)c2C(=O)c3ccccc3-c3onc1c23
Show InChI InChI=1S/C25H25N3O6/c1-2-33-25(32)14-6-5-11-28(13-14)18-12-17(26-10-9-19(29)30)20-21-22(18)27-34-24(21)16-8-4-3-7-15(16)23(20)31/h3-4,7-8,12,14,26H,2,5-6,9-11,13H2,1H3,(H,29,30)
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n/an/a 5.10E+4n/an/an/an/an/an/a



Indiana University

Curated by ChEMBL


Assay Description
Inhibition of urokinase receptor binding to uPA amino terminal fragment by ELISA


Citation and Details
More data for this
Ligand-Target Pair
Urokinase plasminogen activator surface receptor


(Homo sapiens)
BDBM50401176
PNG
(CHEMBL2206362)
Show SMILES Cc1cc2C(=O)c3c(O)c(Br)cc(Nc4cccc(c4)C(O)=O)c3C(=O)c2cc1C
Show InChI InChI=1S/C23H16BrNO5/c1-10-6-14-15(7-11(10)2)21(27)19-18(20(14)26)17(9-16(24)22(19)28)25-13-5-3-4-12(8-13)23(29)30/h3-9,25,28H,1-2H3,(H,29,30)
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n/an/a 6.70E+4n/an/an/an/an/an/a



Indiana University

Curated by ChEMBL


Assay Description
Inhibition of urokinase receptor binding to uPA amino terminal fragment by ELISA


Citation and Details
More data for this
Ligand-Target Pair
Urokinase plasminogen activator surface receptor


(Homo sapiens)
BDBM50401179
PNG
(CHEMBL2206355)
Show SMILES COC(=O)c1cccc(Nc2cc(N3CCCCCC3)c3noc4-c5ccccc5C(=O)c2c34)c1
Show InChI InChI=1S/C28H25N3O4/c1-34-28(33)17-9-8-10-18(15-17)29-21-16-22(31-13-6-2-3-7-14-31)25-24-23(21)26(32)19-11-4-5-12-20(19)27(24)35-30-25/h4-5,8-12,15-16,29H,2-3,6-7,13-14H2,1H3
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n/an/a>1.00E+5n/an/an/an/an/an/a



Indiana University

Curated by ChEMBL


Assay Description
Inhibition of urokinase receptor binding to uPA amino terminal fragment by ELISA


Citation and Details
More data for this
Ligand-Target Pair
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