BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 201 hits Enz. Inhib. hit(s) with Target = 'VCAM-1' AND taxid = 9606   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
VCAM-1


(Homo sapiens (human))
BDBM50105195
PNG
(4-(4-Pyrazol-1-yl-phenoxy)-thieno[2,3-c]pyridine-2...)
Show SMILES CNC(=O)c1cc2c(Oc3ccc(cc3)-n3cccn3)cncc2s1
Show InChI InChI=1S/C18H14N4O2S/c1-19-18(23)16-9-14-15(10-20-11-17(14)25-16)24-13-5-3-12(4-6-13)22-8-2-7-21-22/h2-11H,1H3,(H,19,23)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
PubMed
n/an/a 5n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of VCAM-1 in human endothelial cells


J Med Chem 44: 3469-87 (2001)

More data for this
Ligand-Target Pair
VCAM-1


(Homo sapiens (human))
BDBM50105151
PNG
(4-(4-Vinyl-phenoxy)-thieno[2,3-c]pyridine-2-carbox...)
Show SMILES NC(=O)c1cc2c(Oc3ccc(C=C)cc3)cncc2s1
Show InChI InChI=1S/C16H12N2O2S/c1-2-10-3-5-11(6-4-10)20-13-8-18-9-15-12(13)7-14(21-15)16(17)19/h2-9H,1H2,(H2,17,19)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
PubMed
n/an/a>6n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of VCAM-1 in human endothelial cells


J Med Chem 44: 3469-87 (2001)

More data for this
Ligand-Target Pair
VCAM-1


(Homo sapiens (human))
BDBM50105164
PNG
(4-(4-Thiophen-2-yl-phenoxy)-thieno[2,3-c]pyridine-...)
Show SMILES CNC(=O)c1cc2c(Oc3ccc(cc3)-c3cccs3)cncc2s1
Show InChI InChI=1S/C19H14N2O2S2/c1-20-19(22)17-9-14-15(10-21-11-18(14)25-17)23-13-6-4-12(5-7-13)16-3-2-8-24-16/h2-11H,1H3,(H,20,22)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
PubMed
n/an/a 6n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of VCAM-1 in human endothelial cells


J Med Chem 44: 3469-87 (2001)

More data for this
Ligand-Target Pair
VCAM-1


(Homo sapiens (human))
BDBM50105162
PNG
(4-(4-Bromo-phenoxy)-thieno[2,3-c]pyridine-2-carbox...)
Show SMILES NC(=O)c1cc2c(Oc3ccc(Br)cc3)cncc2s1
Show InChI InChI=1S/C14H9BrN2O2S/c15-8-1-3-9(4-2-8)19-11-6-17-7-13-10(11)5-12(20-13)14(16)18/h1-7H,(H2,16,18)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
PubMed
n/an/a 7n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
In vitro inhibitory potency compared to IL-1beta induced VCAM-1 in human endothelial cells (ELISA assay)


J Med Chem 44: 3469-87 (2001)

More data for this
Ligand-Target Pair
VCAM-1


(Homo sapiens (human))
BDBM50105162
PNG
(4-(4-Bromo-phenoxy)-thieno[2,3-c]pyridine-2-carbox...)
Show SMILES NC(=O)c1cc2c(Oc3ccc(Br)cc3)cncc2s1
Show InChI InChI=1S/C14H9BrN2O2S/c15-8-1-3-9(4-2-8)19-11-6-17-7-13-10(11)5-12(20-13)14(16)18/h1-7H,(H2,16,18)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
PubMed
n/an/a 8n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
In vitro inhibitory potency compared to TNF-alpha induced VCAM-1 in human endothelial cells (ELISA assay)


J Med Chem 44: 3469-87 (2001)

More data for this
Ligand-Target Pair
VCAM-1


(Homo sapiens (human))
BDBM50105178
PNG
(4-(4-Iodo-phenoxy)-thieno[2,3-c]pyridine-2-carboxy...)
Show SMILES NC(=O)c1cc2c(Oc3ccc(I)cc3)cncc2s1
Show InChI InChI=1S/C14H9IN2O2S/c15-8-1-3-9(4-2-8)19-11-6-17-7-13-10(11)5-12(20-13)14(16)18/h1-7H,(H2,16,18)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
PubMed
n/an/a>10n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of VCAM-1 in human endothelial cells


J Med Chem 44: 3469-87 (2001)

More data for this
Ligand-Target Pair
VCAM-1


(Homo sapiens (human))
BDBM50105205
PNG
(4-(4-Imidazol-1-yl-phenoxy)-thieno[2,3-c]pyridine-...)
Show SMILES NC(=O)c1cc2c(Oc3ccc(cc3)-n3ccnc3)cncc2s1
Show InChI InChI=1S/C17H12N4O2S/c18-17(22)15-7-13-14(8-20-9-16(13)24-15)23-12-3-1-11(2-4-12)21-6-5-19-10-21/h1-10H,(H2,18,22)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
PubMed
n/an/a 17n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of VCAM-1 in human endothelial cells


J Med Chem 44: 3469-87 (2001)

More data for this
Ligand-Target Pair
VCAM-1


(Homo sapiens (human))
BDBM50105201
PNG
(4-(4-Imidazol-1-yl-phenoxy)-thieno[2,3-c]pyridine-...)
Show SMILES CNC(=O)c1cc2c(Oc3ccc(cc3)-n3ccnc3)cncc2s1
Show InChI InChI=1S/C18H14N4O2S/c1-19-18(23)16-8-14-15(9-21-10-17(14)25-16)24-13-4-2-12(3-5-13)22-7-6-20-11-22/h2-11H,1H3,(H,19,23)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 19n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of VCAM-1 in human endothelial cells


J Med Chem 44: 3469-87 (2001)

More data for this
Ligand-Target Pair
VCAM-1


(Homo sapiens (human))
BDBM50105156
PNG
(4-{4-[2-(2-Methoxy-ethoxy)-ethoxymethyl]-phenoxy}-...)
Show SMILES CNC(=O)c1cc2c(Oc3ccc(COCCOCCOC)cc3)cncc2s1
Show InChI InChI=1S/C21H24N2O5S/c1-22-21(24)19-11-17-18(12-23-13-20(17)29-19)28-16-5-3-15(4-6-16)14-27-10-9-26-8-7-25-2/h3-6,11-13H,7-10,14H2,1-2H3,(H,22,24)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 20n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
In vitro inhibitory potency compared to IL-1beta induced VCAM-1 in human endothelial cells (ELISA assay)


J Med Chem 44: 3469-87 (2001)

More data for this
Ligand-Target Pair
VCAM-1


(Homo sapiens (human))
BDBM50105162
PNG
(4-(4-Bromo-phenoxy)-thieno[2,3-c]pyridine-2-carbox...)
Show SMILES NC(=O)c1cc2c(Oc3ccc(Br)cc3)cncc2s1
Show InChI InChI=1S/C14H9BrN2O2S/c15-8-1-3-9(4-2-8)19-11-6-17-7-13-10(11)5-12(20-13)14(16)18/h1-7H,(H2,16,18)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
PubMed
n/an/a 20n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
In vitro inhibitory potency compared to PMA induced VCAM-1 in human endothelial cells (ELISA assay)


J Med Chem 44: 3469-87 (2001)

More data for this
Ligand-Target Pair
VCAM-1


(Homo sapiens (human))
BDBM50105156
PNG
(4-{4-[2-(2-Methoxy-ethoxy)-ethoxymethyl]-phenoxy}-...)
Show SMILES CNC(=O)c1cc2c(Oc3ccc(COCCOCCOC)cc3)cncc2s1
Show InChI InChI=1S/C21H24N2O5S/c1-22-21(24)19-11-17-18(12-23-13-20(17)29-19)28-16-5-3-15(4-6-16)14-27-10-9-26-8-7-25-2/h3-6,11-13H,7-10,14H2,1-2H3,(H,22,24)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 20n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
In vitro inhibitory potency compared to PMA induced VCAM-1 in human endothelial cells (ELISA assay)


J Med Chem 44: 3469-87 (2001)

More data for this
Ligand-Target Pair
VCAM-1


(Homo sapiens (human))
BDBM50105185
PNG
(4-(4-Methoxymethyl-phenoxy)-thieno[2,3-c]pyridine-...)
Show SMILES COCc1ccc(Oc2cncc3sc(cc23)C(N)=O)cc1
Show InChI InChI=1S/C16H14N2O3S/c1-20-9-10-2-4-11(5-3-10)21-13-7-18-8-15-12(13)6-14(22-15)16(17)19/h2-8H,9H2,1H3,(H2,17,19)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
PubMed
n/an/a 23n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of VCAM-1 in human endothelial cells


J Med Chem 44: 3469-87 (2001)

More data for this
Ligand-Target Pair
VCAM-1


(Homo sapiens (human))
BDBM50105182
PNG
(4-(4-Methoxymethyl-phenoxy)-thieno[2,3-c]pyridine-...)
Show SMILES CNC(=O)c1cc2c(Oc3ccc(COC)cc3)cncc2s1
Show InChI InChI=1S/C17H16N2O3S/c1-18-17(20)15-7-13-14(8-19-9-16(13)23-15)22-12-5-3-11(4-6-12)10-21-2/h3-9H,10H2,1-2H3,(H,18,20)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a>24n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of VCAM-1 in human endothelial cells


J Med Chem 44: 3469-87 (2001)

More data for this
Ligand-Target Pair
VCAM-1


(Homo sapiens (human))
BDBM50105156
PNG
(4-{4-[2-(2-Methoxy-ethoxy)-ethoxymethyl]-phenoxy}-...)
Show SMILES CNC(=O)c1cc2c(Oc3ccc(COCCOCCOC)cc3)cncc2s1
Show InChI InChI=1S/C21H24N2O5S/c1-22-21(24)19-11-17-18(12-23-13-20(17)29-19)28-16-5-3-15(4-6-16)14-27-10-9-26-8-7-25-2/h3-6,11-13H,7-10,14H2,1-2H3,(H,22,24)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 30n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
In vitro inhibitory potency compared to TNF-alpha induced VCAM-1 in human endothelial cells (ELISA assay)


J Med Chem 44: 3469-87 (2001)

More data for this
Ligand-Target Pair
VCAM-1


(Homo sapiens (human))
BDBM50105162
PNG
(4-(4-Bromo-phenoxy)-thieno[2,3-c]pyridine-2-carbox...)
Show SMILES NC(=O)c1cc2c(Oc3ccc(Br)cc3)cncc2s1
Show InChI InChI=1S/C14H9BrN2O2S/c15-8-1-3-9(4-2-8)19-11-6-17-7-13-10(11)5-12(20-13)14(16)18/h1-7H,(H2,16,18)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
PubMed
n/an/a 48n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of VCAM-1 in human endothelial cells


J Med Chem 44: 3469-87 (2001)

More data for this
Ligand-Target Pair
VCAM-1


(Homo sapiens (human))
BDBM50105173
PNG
(4-(4-Amino-phenoxy)-thieno[2,3-c]pyridine-2-carbox...)
Show SMILES NC(=O)c1cc2c(Oc3ccc(N)cc3)cncc2s1
Show InChI InChI=1S/C14H11N3O2S/c15-8-1-3-9(4-2-8)19-11-6-17-7-13-10(11)5-12(20-13)14(16)18/h1-7H,15H2,(H2,16,18)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
PubMed
n/an/a 64n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of VCAM-1 in human endothelial cells


J Med Chem 44: 3469-87 (2001)

More data for this
Ligand-Target Pair
VCAM-1


(Homo sapiens (human))
BDBM50105159
PNG
(4-(4-Chloro-phenoxy)-thieno[2,3-c]pyridine-2-carbo...)
Show SMILES CNC(=O)c1cc2c(Oc3ccc(Cl)cc3)cncc2s1
Show InChI InChI=1S/C15H11ClN2O2S/c1-17-15(19)13-6-11-12(7-18-8-14(11)21-13)20-10-4-2-9(16)3-5-10/h2-8H,1H3,(H,17,19)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 70n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
In vitro inhibitory potency compared to IL-1beta induced VCAM-1 expression in human endothelial cells (ELISA assay)


J Med Chem 44: 3469-87 (2001)

More data for this
Ligand-Target Pair
VCAM-1


(Homo sapiens (human))
BDBM50105209
PNG
(4-[4-(1-Hydroxymethyl-cyclopropyl)-phenoxy]-thieno...)
Show SMILES CNC(=O)c1cc2c(Oc3ccc(cc3)C3(CO)CC3)cncc2s1
Show InChI InChI=1S/C19H18N2O3S/c1-20-18(23)16-8-14-15(9-21-10-17(14)25-16)24-13-4-2-12(3-5-13)19(11-22)6-7-19/h2-5,8-10,22H,6-7,11H2,1H3,(H,20,23)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
PubMed
n/an/a 74n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of VCAM-1 in human endothelial cells


J Med Chem 44: 3469-87 (2001)

More data for this
Ligand-Target Pair
VCAM-1


(Homo sapiens (human))
BDBM50105202
PNG
(4-(Biphenyl-4-yloxy)-thieno[2,3-c]pyridine-2-carbo...)
Show SMILES CNC(=O)c1cc2c(Oc3ccc(cc3)-c3ccccc3)cncc2s1
Show InChI InChI=1S/C21H16N2O2S/c1-22-21(24)19-11-17-18(12-23-13-20(17)26-19)25-16-9-7-15(8-10-16)14-5-3-2-4-6-14/h2-13H,1H3,(H,22,24)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
PubMed
n/an/a 79n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of VCAM-1 in human endothelial cells


J Med Chem 44: 3469-87 (2001)

More data for this
Ligand-Target Pair
VCAM-1


(Homo sapiens (human))
BDBM50105215
PNG
(4-(4-Cyano-phenoxy)-thieno[2,3-c]pyridine-2-carbox...)
Show SMILES NC(=O)c1cc2c(Oc3ccc(cc3)C#N)cncc2s1
Show InChI InChI=1S/C15H9N3O2S/c16-6-9-1-3-10(4-2-9)20-12-7-18-8-14-11(12)5-13(21-14)15(17)19/h1-5,7-8H,(H2,17,19)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
PubMed
n/an/a 85n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of VCAM-1 in human endothelial cells


J Med Chem 44: 3469-87 (2001)

More data for this
Ligand-Target Pair
VCAM-1


(Homo sapiens (human))
BDBM50105197
PNG
(4-(4-Cyano-phenoxy)-thieno[2,3-c]pyridine-2-carbox...)
Show SMILES CNC(=O)c1cc2c(Oc3ccc(cc3)C#N)cncc2s1
Show InChI InChI=1S/C16H11N3O2S/c1-18-16(20)14-6-12-13(8-19-9-15(12)22-14)21-11-4-2-10(7-17)3-5-11/h2-6,8-9H,1H3,(H,18,20)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 91n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of VCAM-1 in human endothelial cells


J Med Chem 44: 3469-87 (2001)

More data for this
Ligand-Target Pair
VCAM-1


(Homo sapiens (human))
BDBM50105222
PNG
(4-(4-Trifluoromethyl-phenoxy)-thieno[2,3-c]pyridin...)
Show SMILES NC(=O)c1cc2c(Oc3ccc(cc3)C(F)(F)F)cncc2s1
Show InChI InChI=1S/C15H9F3N2O2S/c16-15(17,18)8-1-3-9(4-2-8)22-11-6-20-7-13-10(11)5-12(23-13)14(19)21/h1-7H,(H2,19,21)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
PubMed
n/an/a>100n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of VCAM-1 in human endothelial cells


J Med Chem 44: 3469-87 (2001)

More data for this
Ligand-Target Pair
VCAM-1


(Homo sapiens (human))
BDBM50098490
PNG
(4-(4-Trifluoromethyl-phenylsulfanyl)-thieno[2,3-c]...)
Show SMILES NC(=O)c1cc2c(Sc3ccc(cc3)C(F)(F)F)cncc2s1
Show InChI InChI=1S/C15H9F3N2OS2/c16-15(17,18)8-1-3-9(4-2-8)22-12-6-20-7-13-10(12)5-11(23-13)14(19)21/h1-7H,(H2,19,21)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
PubMed
n/an/a>100n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
In vitro potency against TNF alpha induced expresion of VCAM-1 on human vascular endothelial cells using CAM ELISA assay


J Med Chem 44: 988-1002 (2001)

More data for this
Ligand-Target Pair
VCAM-1


(Homo sapiens (human))
BDBM50105161
PNG
(4-(4-Isopropyl-phenoxy)-thieno[2,3-c]pyridine-2-ca...)
Show SMILES CC(C)c1ccc(Oc2cncc3sc(cc23)C(N)=O)cc1
Show InChI InChI=1S/C17H16N2O2S/c1-10(2)11-3-5-12(6-4-11)21-14-8-19-9-16-13(14)7-15(22-16)17(18)20/h3-10H,1-2H3,(H2,18,20)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
PubMed
n/an/a>100n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of VCAM-1 in human endothelial cells


J Med Chem 44: 3469-87 (2001)

More data for this
Ligand-Target Pair
VCAM-1


(Homo sapiens (human))
BDBM50105156
PNG
(4-{4-[2-(2-Methoxy-ethoxy)-ethoxymethyl]-phenoxy}-...)
Show SMILES CNC(=O)c1cc2c(Oc3ccc(COCCOCCOC)cc3)cncc2s1
Show InChI InChI=1S/C21H24N2O5S/c1-22-21(24)19-11-17-18(12-23-13-20(17)29-19)28-16-5-3-15(4-6-16)14-27-10-9-26-8-7-25-2/h3-6,11-13H,7-10,14H2,1-2H3,(H,22,24)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 120n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of VCAM-1 in human endothelial cells


J Med Chem 44: 3469-87 (2001)

More data for this
Ligand-Target Pair
VCAM-1


(Homo sapiens (human))
BDBM50105152
PNG
(4-(4-Chloro-phenoxy)-thieno[2,3-c]pyridine-2-carbo...)
Show SMILES CN(C)C(=O)c1cc2c(Oc3ccc(Cl)cc3)cncc2s1
Show InChI InChI=1S/C16H13ClN2O2S/c1-19(2)16(20)14-7-12-13(8-18-9-15(12)22-14)21-11-5-3-10(17)4-6-11/h3-9H,1-2H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
PubMed
n/an/a 130n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of VCAM-1 in human endothelial cells


J Med Chem 44: 3469-87 (2001)

More data for this
Ligand-Target Pair
VCAM-1


(Homo sapiens (human))
BDBM50105221
PNG
(4-(4-Ethyl-phenoxy)-thieno[2,3-c]pyridine-2-carbox...)
Show SMILES CCc1ccc(Oc2cncc3sc(cc23)C(N)=O)cc1
Show InChI InChI=1S/C16H14N2O2S/c1-2-10-3-5-11(6-4-10)20-13-8-18-9-15-12(13)7-14(21-15)16(17)19/h3-9H,2H2,1H3,(H2,17,19)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
PubMed
n/an/a 140n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of VCAM-1 in human endothelial cells


J Med Chem 44: 3469-87 (2001)

More data for this
Ligand-Target Pair
VCAM-1


(Homo sapiens (human))
BDBM50105191
PNG
(4-[4-(3-Morpholin-4-yl-3-oxo-propenyl)-phenoxy]-th...)
Show SMILES NC(=O)c1cc2c(Oc3ccc(\C=C\C(=O)N4CCOCC4)cc3)cncc2s1
Show InChI InChI=1S/C21H19N3O4S/c22-21(26)18-11-16-17(12-23-13-19(16)29-18)28-15-4-1-14(2-5-15)3-6-20(25)24-7-9-27-10-8-24/h1-6,11-13H,7-10H2,(H2,22,26)/b6-3+
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a>140n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of VCAM-1 in human endothelial cells


J Med Chem 44: 3469-87 (2001)

More data for this
Ligand-Target Pair
VCAM-1


(Homo sapiens (human))
BDBM50105166
PNG
(4-(4-Fluoro-phenoxy)-thieno[2,3-c]pyridine-2-carbo...)
Show SMILES NC(=O)c1cc2c(Oc3ccc(F)cc3)cncc2s1
Show InChI InChI=1S/C14H9FN2O2S/c15-8-1-3-9(4-2-8)19-11-6-17-7-13-10(11)5-12(20-13)14(16)18/h1-7H,(H2,16,18)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
PubMed
n/an/a>153n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of VCAM-1 in human endothelial cells


J Med Chem 44: 3469-87 (2001)

More data for this
Ligand-Target Pair
VCAM-1


(Homo sapiens (human))
BDBM50105175
PNG
(4-(4-{2-[2-(2-Ethoxy-ethoxy)-ethoxy]-1,1-difluoro-...)
Show SMILES CCOCCOCCOCC(F)(F)c1ccc(Oc2cncc3sc(cc23)C(=O)NC)cc1
Show InChI InChI=1S/C23H26F2N2O5S/c1-3-29-8-9-30-10-11-31-15-23(24,25)16-4-6-17(7-5-16)32-19-13-27-14-21-18(19)12-20(33-21)22(28)26-2/h4-7,12-14H,3,8-11,15H2,1-2H3,(H,26,28)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
PubMed
n/an/a 170n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of VCAM-1 in human endothelial cells


J Med Chem 44: 3469-87 (2001)

More data for this
Ligand-Target Pair
VCAM-1


(Homo sapiens (human))
BDBM50029632
PNG
(3-Isopropoxy-5-methoxy-benzo[b]thiophene-2-carboxy...)
Show SMILES COc1ccc2sc(C(N)=O)c(OC(C)C)c2c1
Show InChI InChI=1S/C13H15NO3S/c1-7(2)17-11-9-6-8(16-3)4-5-10(9)18-12(11)13(14)15/h4-7H,1-3H3,(H2,14,15)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
PubMed
n/an/a 175n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
In vitro potency against TNF alpha induced expresion of VCAM-1 on human vascular endothelial cells using CAM ELISA assay


J Med Chem 44: 988-1002 (2001)

More data for this
Ligand-Target Pair
VCAM-1


(Homo sapiens (human))
BDBM50105177
PNG
(4-[4-(3-Methyl-3H-imidazol-4-yl)-phenoxy]-thieno[2...)
Show SMILES CNC(=O)c1cc2c(Oc3ccc(cc3)-c3cncn3C)cncc2s1
Show InChI InChI=1S/C19H16N4O2S/c1-20-19(24)17-7-14-16(9-21-10-18(14)26-17)25-13-5-3-12(4-6-13)15-8-22-11-23(15)2/h3-11H,1-2H3,(H,20,24)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a>180n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of VCAM-1 in human endothelial cells


J Med Chem 44: 3469-87 (2001)

More data for this
Ligand-Target Pair
VCAM-1


(Homo sapiens (human))
BDBM50105211
PNG
(4-(4-Hydroxymethyl-phenoxy)-thieno[2,3-c]pyridine-...)
Show SMILES NC(=O)c1cc2c(Oc3ccc(CO)cc3)cncc2s1
Show InChI InChI=1S/C15H12N2O3S/c16-15(19)13-5-11-12(6-17-7-14(11)21-13)20-10-3-1-9(8-18)2-4-10/h1-7,18H,8H2,(H2,16,19)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
PubMed
n/an/a 191n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of VCAM-1 in human endothelial cells


J Med Chem 44: 3469-87 (2001)

More data for this
Ligand-Target Pair
VCAM-1


(Homo sapiens (human))
BDBM50105159
PNG
(4-(4-Chloro-phenoxy)-thieno[2,3-c]pyridine-2-carbo...)
Show SMILES CNC(=O)c1cc2c(Oc3ccc(Cl)cc3)cncc2s1
Show InChI InChI=1S/C15H11ClN2O2S/c1-17-15(19)13-6-11-12(7-18-8-14(11)21-13)20-10-4-2-9(16)3-5-10/h2-8H,1H3,(H,17,19)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 200n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
In vitro inhibitory potency compared to PMA induced VCAM-1 expression in human endothelial cells (ELISA assay)


J Med Chem 44: 3469-87 (2001)

More data for this
Ligand-Target Pair
VCAM-1


(Homo sapiens (human))
BDBM50098482
PNG
(4-(4-Methoxy-phenylsulfanyl)-thieno[2,3-c]pyridine...)
Show SMILES COc1ccc(Sc2cncc3sc(cc23)C(N)=O)cc1
Show InChI InChI=1S/C15H12N2O2S2/c1-19-9-2-4-10(5-3-9)20-13-7-17-8-14-11(13)6-12(21-14)15(16)18/h2-8H,1H3,(H2,16,18)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
PubMed
n/an/a>200n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
In vitro potency against TNF alpha induced expresion of VCAM-1 on human vascular endothelial cells using CAM ELISA assay


J Med Chem 44: 988-1002 (2001)

More data for this
Ligand-Target Pair
VCAM-1


(Homo sapiens (human))
BDBM50105149
PNG
(4-(4-[1,2,4]Triazol-1-yl-phenoxy)-thieno[2,3-c]pyr...)
Show SMILES CNC(=O)c1cc2c(Oc3ccc(cc3)-n3cncn3)cncc2s1
Show InChI InChI=1S/C17H13N5O2S/c1-18-17(23)15-6-13-14(7-19-8-16(13)25-15)24-12-4-2-11(3-5-12)22-10-20-9-21-22/h2-10H,1H3,(H,18,23)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 240n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of VCAM-1 in human endothelial cells


J Med Chem 44: 3469-87 (2001)

More data for this
Ligand-Target Pair
VCAM-1


(Homo sapiens (human))
BDBM50105214
PNG
(4-(2-Bromo-4-chloro-phenoxy)-thieno[2,3-c]pyridine...)
Show SMILES NC(=O)c1cc2c(Oc3ccc(Cl)cc3Br)cncc2s1
Show InChI InChI=1S/C14H8BrClN2O2S/c15-9-3-7(16)1-2-10(9)20-11-5-18-6-13-8(11)4-12(21-13)14(17)19/h1-6H,(H2,17,19)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
PubMed
n/an/a 330n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of VCAM-1 in human endothelial cells


J Med Chem 44: 3469-87 (2001)

More data for this
Ligand-Target Pair
VCAM-1


(Homo sapiens (human))
BDBM50105194
PNG
(4-(4-Trifluoromethoxy-phenoxy)-thieno[2,3-c]pyridi...)
Show SMILES CNC(=O)c1cc2c(Oc3ccc(OC(F)(F)F)cc3)cncc2s1
Show InChI InChI=1S/C16H11F3N2O3S/c1-20-15(22)13-6-11-12(7-21-8-14(11)25-13)23-9-2-4-10(5-3-9)24-16(17,18)19/h2-8H,1H3,(H,20,22)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
PubMed
n/an/a 370n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of VCAM-1 in human endothelial cells


J Med Chem 44: 3469-87 (2001)

More data for this
Ligand-Target Pair
VCAM-1


(Homo sapiens (human))
BDBM50105158
PNG
(4-(4-Cyano-phenoxy)-thieno[2,3-c]pyridine-2-carbox...)
Show SMILES CCCCCCCCc1ccc(Oc2cncc3sc(cc23)C(N)=O)cc1
Show InChI InChI=1S/C22H26N2O2S/c1-2-3-4-5-6-7-8-16-9-11-17(12-10-16)26-19-14-24-15-21-18(19)13-20(27-21)22(23)25/h9-15H,2-8H2,1H3,(H2,23,25)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
PubMed
n/an/a>400n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
In vitro inhibitory potency against VCAM-1 receptor in human endothelial cells (ELISA assay)


J Med Chem 44: 3469-87 (2001)

More data for this
Ligand-Target Pair
VCAM-1


(Homo sapiens (human))
BDBM50105217
PNG
(4-(4-{1-[2-(2-Ethoxy-ethoxy)-ethoxymethyl]-cyclopr...)
Show SMILES CCOCCOCCOCC1(CC1)c1ccc(Oc2cncc3sc(cc23)C(=O)NC)cc1
Show InChI InChI=1S/C25H30N2O5S/c1-3-29-10-11-30-12-13-31-17-25(8-9-25)18-4-6-19(7-5-18)32-21-15-27-16-23-20(21)14-22(33-23)24(28)26-2/h4-7,14-16H,3,8-13,17H2,1-2H3,(H,26,28)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
PubMed
n/an/a 420n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of VCAM-1 in human endothelial cells


J Med Chem 44: 3469-87 (2001)

More data for this
Ligand-Target Pair
VCAM-1


(Homo sapiens (human))
BDBM50105145
PNG
(4-[4-(1,1-Difluoro-2-hydroxy-ethyl)-phenoxy]-thien...)
Show SMILES CNC(=O)c1cc2c(Oc3ccc(cc3)C(F)(F)CO)cncc2s1
Show InChI InChI=1S/C17H14F2N2O3S/c1-20-16(23)14-6-12-13(7-21-8-15(12)25-14)24-11-4-2-10(3-5-11)17(18,19)9-22/h2-8,22H,9H2,1H3,(H,20,23)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
PubMed
n/an/a 470n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of VCAM-1 in human endothelial cells


J Med Chem 44: 3469-87 (2001)

More data for this
Ligand-Target Pair
VCAM-1


(Homo sapiens (human))
BDBM50098514
PNG
(4-(2,4-Dimethyl-phenylsulfanyl)-thieno[2,3-c]pyrid...)
Show SMILES Cc1ccc(Sc2cncc3sc(cc23)C(N)=O)c(C)c1
Show InChI InChI=1S/C16H14N2OS2/c1-9-3-4-12(10(2)5-9)20-14-7-18-8-15-11(14)6-13(21-15)16(17)19/h3-8H,1-2H3,(H2,17,19)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
PubMed
n/an/a 770n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
In vitro potency against TNF alpha induced expresion of VCAM-1 on human vascular endothelial cells using CAM ELISA assay


J Med Chem 44: 988-1002 (2001)

More data for this
Ligand-Target Pair
VCAM-1


(Homo sapiens (human))
BDBM50105212
PNG
(4-(2-Allyl-phenoxy)-thieno[2,3-c]pyridine-2-carbox...)
Show SMILES NC(=O)c1cc2c(Oc3ccccc3CC=C)cncc2s1
Show InChI InChI=1S/C17H14N2O2S/c1-2-5-11-6-3-4-7-13(11)21-14-9-19-10-16-12(14)8-15(22-16)17(18)20/h2-4,6-10H,1,5H2,(H2,18,20)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
PubMed
n/an/a 780n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of VCAM-1 in human endothelial cells


J Med Chem 44: 3469-87 (2001)

More data for this
Ligand-Target Pair
VCAM-1


(Homo sapiens (human))
BDBM50105163
PNG
(4-(3-Chloro-phenoxy)-thieno[2,3-c]pyridine-2-carbo...)
Show SMILES NC(=O)c1cc2c(Oc3cccc(Cl)c3)cncc2s1
Show InChI InChI=1S/C14H9ClN2O2S/c15-8-2-1-3-9(4-8)19-11-6-17-7-13-10(11)5-12(20-13)14(16)18/h1-7H,(H2,16,18)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
PubMed
n/an/a 850n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of VCAM-1 in human endothelial cells


J Med Chem 44: 3469-87 (2001)

More data for this
Ligand-Target Pair
VCAM-1


(Homo sapiens (human))
BDBM50105198
PNG
(4-(4-Chloro-phenoxy)-thieno[2,3-c]pyridine-2-carbo...)
Show SMILES OCCNC(=O)c1cc2c(Oc3ccc(Cl)cc3)cncc2s1
Show InChI InChI=1S/C16H13ClN2O3S/c17-10-1-3-11(4-2-10)22-13-8-18-9-15-12(13)7-14(23-15)16(21)19-5-6-20/h1-4,7-9,20H,5-6H2,(H,19,21)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 880n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of VCAM-1 in human endothelial cells


J Med Chem 44: 3469-87 (2001)

More data for this
Ligand-Target Pair
VCAM-1


(Homo sapiens (human))
BDBM50105187
PNG
(4-[4-(1,2-Dihydroxy-ethyl)-phenoxy]-thieno[2,3-c]p...)
Show SMILES NC(=O)c1cc2c(Oc3ccc(cc3)C(O)CO)cncc2s1
Show InChI InChI=1S/C16H14N2O4S/c17-16(21)14-5-11-13(6-18-7-15(11)23-14)22-10-3-1-9(2-4-10)12(20)8-19/h1-7,12,19-20H,8H2,(H2,17,21)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
PubMed
n/an/a 930n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of VCAM-1 in human endothelial cells


J Med Chem 44: 3469-87 (2001)

More data for this
Ligand-Target Pair
VCAM-1


(Homo sapiens (human))
BDBM50105174
PNG
(4-[4-(2,3-Dihydroxy-propylcarbamoyl)-phenoxy]-thie...)
Show SMILES NC(=O)c1cc2c(Oc3ccc(cc3)C(=O)NCC(O)CO)cncc2s1
Show InChI InChI=1S/C18H17N3O5S/c19-17(24)15-5-13-14(7-20-8-16(13)27-15)26-12-3-1-10(2-4-12)18(25)21-6-11(23)9-22/h1-5,7-8,11,22-23H,6,9H2,(H2,19,24)(H,21,25)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a>1.00E+3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of VCAM-1 in human endothelial cells


J Med Chem 44: 3469-87 (2001)

More data for this
Ligand-Target Pair
VCAM-1


(Homo sapiens (human))
BDBM50105190
PNG
(4-[4-(2-Morpholin-4-yl-ethylcarbamoyl)-phenoxy]-th...)
Show SMILES NC(=O)c1cc2c(Oc3ccc(cc3)C(=O)NCCN3CCOCC3)cncc2s1
Show InChI InChI=1S/C21H22N4O4S/c22-20(26)18-11-16-17(12-23-13-19(16)30-18)29-15-3-1-14(2-4-15)21(27)24-5-6-25-7-9-28-10-8-25/h1-4,11-13H,5-10H2,(H2,22,26)(H,24,27)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
PubMed
n/an/a>1.00E+3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of VCAM-1 in human endothelial cells


J Med Chem 44: 3469-87 (2001)

More data for this
Ligand-Target Pair
VCAM-1


(Homo sapiens (human))
BDBM50105220
PNG
(4-[4-(5-Trifluoromethyl-[1,2,4]oxadiazol-3-yl)-phe...)
Show SMILES CNC(=O)c1cc2c(Oc3ccc(cc3)-c3noc(n3)C(F)(F)F)cncc2s1
Show InChI InChI=1S/C18H11F3N4O3S/c1-22-16(26)13-6-11-12(7-23-8-14(11)29-13)27-10-4-2-9(3-5-10)15-24-17(28-25-15)18(19,20)21/h2-8H,1H3,(H,22,26)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

AffyNet 
PubMed
n/an/a>1.00E+3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of VCAM-1 in human endothelial cells


J Med Chem 44: 3469-87 (2001)

More data for this
Ligand-Target Pair
VCAM-1


(Homo sapiens (human))
BDBM50105219
PNG
(4-(3-Chloro-4-methyl-phenoxy)-thieno[2,3-c]pyridin...)
Show SMILES Cc1ccc(Oc2cncc3sc(cc23)C(N)=O)cc1Cl
Show InChI InChI=1S/C15H11ClN2O2S/c1-8-2-3-9(4-11(8)16)20-12-6-18-7-14-10(12)5-13(21-14)15(17)19/h2-7H,1H3,(H2,17,19)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
PubMed
n/an/a>1.00E+3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of VCAM-1 in human endothelial cells


J Med Chem 44: 3469-87 (2001)

More data for this
Ligand-Target Pair
Displayed 1 to 50 (of 201 total )  |  Next  |  Last  >>
Jump to: