BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 131 hits Enz. Inhib. hit(s) with Target = 'Vascular endothelial growth factor A' AND taxid = 9606   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Vascular endothelial growth factor A


(Homo sapiens (Human))
BDBM50003017
PNG
(CHEMBL3234202)
Show SMILES CC[C@H](C)[C@@H]1N(C)C(=O)[C@H](C)N(C)C(=O)[C@H](Cc2ccc(OC)cc2)NC(=O)CC[C@@H]2CSC(=N2)[C@@H](C)[C@@H](O)C[C@H](C)C[C@H](OC(=O)[C@@H]2CCCN2C1=O)C(C)(C)C
Show InChI InChI=1S/C44H69N5O8S/c1-12-27(3)38-42(54)49-21-13-14-34(49)43(55)57-36(44(6,7)8)23-26(2)22-35(50)28(4)39-45-31(25-58-39)17-20-37(51)46-33(24-30-15-18-32(56-11)19-16-30)41(53)47(9)29(5)40(52)48(38)10/h15-16,18-19,26-29,31,33-36,38,50H,12-14,17,20-25H2,1-11H3,(H,46,51)/t26-,27-,28-,29-,31+,33-,34-,35-,36-,38-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
Article
PubMed
n/an/a 0.120n/an/an/an/an/an/a



University of Florida

Curated by ChEMBL


Assay Description
Inhibition of VEGF-A production in human HCT116 cells after 12 hrs by alphaLISA assay


Citation and Details
More data for this
Ligand-Target Pair
Vascular endothelial growth factor A


(Homo sapiens (Human))
BDBM50002930
PNG
(CHEMBL3234200)
Show SMILES CC[C@H](C)[C@@H]1N(C)C(=O)[C@H](C)N(C)C(=O)[C@H](Cc2ccc(OC)cc2)NC(=O)CC[C@H]2CSC(C[C@@H](O)C[C@H](C)C[C@H](OC(=O)[C@@H]3CCCN3C1=O)C(C)(C)C)=N2
Show InChI InChI=1S/C43H67N5O8S/c1-11-27(3)38-41(53)48-20-12-13-34(48)42(54)56-35(43(5,6)7)22-26(2)21-31(49)24-37-44-30(25-57-37)16-19-36(50)45-33(23-29-14-17-32(55-10)18-15-29)40(52)46(8)28(4)39(51)47(38)9/h14-15,17-18,26-28,30-31,33-35,38,49H,11-13,16,19-25H2,1-10H3,(H,45,50)/t26-,27-,28-,30-,31-,33-,34-,35-,38-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 0.300n/an/an/an/an/an/a



University of Florida

Curated by ChEMBL


Assay Description
Inhibition of VEGF-A production in human HCT116 cells after 12 hrs by alphaLISA assay


Citation and Details
More data for this
Ligand-Target Pair
Vascular endothelial growth factor A


(Homo sapiens (Human))
BDBM50002918
PNG
(APRATOXIN S4 | Apratoxin S4)
Show SMILES CC[C@H](C)[C@@H]1N(C)C(=O)[C@H](C)N(C)C(=O)[C@H](Cc2ccc(OC)cc2)NC(=O)CC[C@H]2CSC(=N2)[C@@H](C)[C@@H](O)C[C@H](C)C[C@H](OC(=O)[C@@H]2CCCN2C1=O)C(C)(C)C
Show InChI InChI=1S/C44H69N5O8S/c1-12-27(3)38-42(54)49-21-13-14-34(49)43(55)57-36(44(6,7)8)23-26(2)22-35(50)28(4)39-45-31(25-58-39)17-20-37(51)46-33(24-30-15-18-32(56-11)19-16-30)41(53)47(9)29(5)40(52)48(38)10/h15-16,18-19,26-29,31,33-36,38,50H,12-14,17,20-25H2,1-11H3,(H,46,51)/t26-,27-,28-,29-,31-,33-,34-,35-,36-,38-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 0.320n/an/an/an/an/an/a



University of Florida

Curated by ChEMBL


Assay Description
Inhibition of VEGF-A production in human HCT116 cells after 12 hrs by alphaLISA assay


Citation and Details
More data for this
Ligand-Target Pair
Vascular endothelial growth factor A


(Homo sapiens (Human))
BDBM50002932
PNG
(CHEMBL3234201)
Show SMILES CC[C@H](C)[C@@H]1N(C)C(=O)[C@H](C)N(C)C(=O)[C@H](Cc2ccc(OC)cc2)NC(=O)CC[C@H]2CSC(=N2)C(C)(C)[C@@H](O)C[C@H](C)C[C@H](OC(=O)[C@@H]2CCCN2C1=O)C(C)(C)C
Show InChI InChI=1S/C45H71N5O8S/c1-13-28(3)38-41(55)50-22-14-15-34(50)42(56)58-36(44(5,6)7)24-27(2)23-35(51)45(8,9)43-46-31(26-59-43)18-21-37(52)47-33(25-30-16-19-32(57-12)20-17-30)40(54)48(10)29(4)39(53)49(38)11/h16-17,19-20,27-29,31,33-36,38,51H,13-15,18,21-26H2,1-12H3,(H,47,52)/t27-,28-,29-,31-,33-,34-,35-,36-,38-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 0.470n/an/an/an/an/an/a



University of Florida

Curated by ChEMBL


Assay Description
Inhibition of VEGF-A production in human HCT116 cells after 12 hrs by alphaLISA assay


Citation and Details
More data for this
Ligand-Target Pair
Vascular endothelial growth factor A


(Homo sapiens (Human))
BDBM102349
PNG
(US8536181, E33 | US9278930, E33)
Show SMILES CN(CC(O)=O)Cc1ccn(c(=O)c1O)S(=O)(=O)c1ccc(C)cc1
Show InChI InChI=1S/C16H18N2O6S/c1-11-3-5-13(6-4-11)25(23,24)18-8-7-12(15(21)16(18)22)9-17(2)10-14(19)20/h3-8,21H,9-10H2,1-2H3,(H,19,20)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
US Patent
n/an/a 2.10E+3n/an/an/an/an/an/a



Aerpio Therapeutics Inc.

US Patent


Assay Description
ELISA assay using VEGF.


US Patent US8536181 (2013)

More data for this
Ligand-Target Pair
Vascular endothelial growth factor A


(Homo sapiens (Human))
BDBM102349
PNG
(US8536181, E33 | US9278930, E33)
Show SMILES CN(CC(O)=O)Cc1ccn(c(=O)c1O)S(=O)(=O)c1ccc(C)cc1
Show InChI InChI=1S/C16H18N2O6S/c1-11-3-5-13(6-4-11)25(23,24)18-8-7-12(15(21)16(18)22)9-17(2)10-14(19)20/h3-8,21H,9-10H2,1-2H3,(H,19,20)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
US Patent
n/an/a 2.10E+3n/an/an/an/an/an/a



AERPIO THERAPEUTICS, INC.

US Patent


Assay Description
HEK293 cells are seeded in 96-well poly-lysine coated plates at 20,000 cells per well in DMEM (10% FBS, 1% NEAA, 0.1% glutamine). Following overnight...


US Patent US9278930 (2016)

More data for this
Ligand-Target Pair
Vascular endothelial growth factor A


(Homo sapiens (Human))
BDBM102349
PNG
(US8536181, E33 | US9278930, E33)
Show SMILES CN(CC(O)=O)Cc1ccn(c(=O)c1O)S(=O)(=O)c1ccc(C)cc1
Show InChI InChI=1S/C16H18N2O6S/c1-11-3-5-13(6-4-11)25(23,24)18-8-7-12(15(21)16(18)22)9-17(2)10-14(19)20/h3-8,21H,9-10H2,1-2H3,(H,19,20)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
US Patent
n/an/a 2.10E+3n/an/an/an/an/an/a



Aerpio Therapeutics Inc.

US Patent


Assay Description
HEK293 cells are seeded in 96-well poly-lysine coated plates at 20,000 cells per well in DMEM (10% FBS, 1% NEAA, 0.1% glutamine). Following overnight...


US Patent US8778412 (2014)

More data for this
Ligand-Target Pair
Vascular endothelial growth factor A


(Homo sapiens (Human))
BDBM102350
PNG
(US8536181, F3 | US9278930, F3)
Show SMILES Oc1cccn(Cc2ccc(Cl)cc2)c1=O
Show InChI InChI=1S/C12H10ClNO2/c13-10-5-3-9(4-6-10)8-14-7-1-2-11(15)12(14)16/h1-7,15H,8H2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
US Patent
n/an/a 7.40E+3n/an/an/an/an/an/a



Aerpio Therapeutics Inc.

US Patent


Assay Description
HEK293 cells are seeded in 96-well poly-lysine coated plates at 20,000 cells per well in DMEM (10% FBS, 1% NEAA, 0.1% glutamine). Following overnight...


US Patent US8778412 (2014)

More data for this
Ligand-Target Pair
Vascular endothelial growth factor A


(Homo sapiens (Human))
BDBM102350
PNG
(US8536181, F3 | US9278930, F3)
Show SMILES Oc1cccn(Cc2ccc(Cl)cc2)c1=O
Show InChI InChI=1S/C12H10ClNO2/c13-10-5-3-9(4-6-10)8-14-7-1-2-11(15)12(14)16/h1-7,15H,8H2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
US Patent
n/an/a 7.40E+3n/an/an/an/an/an/a



AERPIO THERAPEUTICS, INC.

US Patent


Assay Description
HEK293 cells are seeded in 96-well poly-lysine coated plates at 20,000 cells per well in DMEM (10% FBS, 1% NEAA, 0.1% glutamine). Following overnight...


US Patent US9278930 (2016)

More data for this
Ligand-Target Pair
Vascular endothelial growth factor A


(Homo sapiens (Human))
BDBM102350
PNG
(US8536181, F3 | US9278930, F3)
Show SMILES Oc1cccn(Cc2ccc(Cl)cc2)c1=O
Show InChI InChI=1S/C12H10ClNO2/c13-10-5-3-9(4-6-10)8-14-7-1-2-11(15)12(14)16/h1-7,15H,8H2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
US Patent
n/an/a 7.40E+3n/an/an/an/an/an/a



Aerpio Therapeutics Inc.

US Patent


Assay Description
ELISA assay using VEGF.


US Patent US8536181 (2013)

More data for this
Ligand-Target Pair
Vascular endothelial growth factor A


(Homo sapiens (Human))
BDBM102343
PNG
(US8536181, B9 | US9278930, B9)
Show SMILES Oc1c(CN2CCN(Cc3ccccc3)CC2)ccn(Cc2ccccc2)c1=O
Show InChI InChI=1S/C24H27N3O2/c28-23-22(11-12-27(24(23)29)18-21-9-5-2-6-10-21)19-26-15-13-25(14-16-26)17-20-7-3-1-4-8-20/h1-12,28H,13-19H2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
US Patent
n/an/a 1.26E+4n/an/an/an/an/an/a



AERPIO THERAPEUTICS, INC.

US Patent


Assay Description
HEK293 cells are seeded in 96-well poly-lysine coated plates at 20,000 cells per well in DMEM (10% FBS, 1% NEAA, 0.1% glutamine). Following overnight...


US Patent US9278930 (2016)

More data for this
Ligand-Target Pair
Vascular endothelial growth factor A


(Homo sapiens (Human))
BDBM102343
PNG
(US8536181, B9 | US9278930, B9)
Show SMILES Oc1c(CN2CCN(Cc3ccccc3)CC2)ccn(Cc2ccccc2)c1=O
Show InChI InChI=1S/C24H27N3O2/c28-23-22(11-12-27(24(23)29)18-21-9-5-2-6-10-21)19-26-15-13-25(14-16-26)17-20-7-3-1-4-8-20/h1-12,28H,13-19H2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
US Patent
n/an/a 1.26E+4n/an/an/an/an/an/a



Aerpio Therapeutics Inc.

US Patent


Assay Description
HEK293 cells are seeded in 96-well poly-lysine coated plates at 20,000 cells per well in DMEM (10% FBS, 1% NEAA, 0.1% glutamine). Following overnight...


US Patent US8778412 (2014)

More data for this
Ligand-Target Pair
Vascular endothelial growth factor A


(Homo sapiens (Human))
BDBM102343
PNG
(US8536181, B9 | US9278930, B9)
Show SMILES Oc1c(CN2CCN(Cc3ccccc3)CC2)ccn(Cc2ccccc2)c1=O
Show InChI InChI=1S/C24H27N3O2/c28-23-22(11-12-27(24(23)29)18-21-9-5-2-6-10-21)19-26-15-13-25(14-16-26)17-20-7-3-1-4-8-20/h1-12,28H,13-19H2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
US Patent
n/an/a 1.26E+4n/an/an/an/an/an/a



Aerpio Therapeutics Inc.

US Patent


Assay Description
ELISA assay using VEGF.


US Patent US8536181 (2013)

More data for this
Ligand-Target Pair
Vascular endothelial growth factor A


(Homo sapiens (Human))
BDBM102348
PNG
(US8536181, A41 | US9278930, A41)
Show SMILES CC(C)(C)OC(=O)N1CCN(Cc2ccn(Cc3ccc(Cl)cc3)c(=O)c2O)CC1
Show InChI InChI=1S/C22H28ClN3O4/c1-22(2,3)30-21(29)25-12-10-24(11-13-25)15-17-8-9-26(20(28)19(17)27)14-16-4-6-18(23)7-5-16/h4-9,27H,10-15H2,1-3H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
AffyNet 
US Patent
n/an/a 1.66E+4n/an/an/an/an/an/a



Aerpio Therapeutics Inc.

US Patent


Assay Description
HEK293 cells are seeded in 96-well poly-lysine coated plates at 20,000 cells per well in DMEM (10% FBS, 1% NEAA, 0.1% glutamine). Following overnight...


US Patent US8778412 (2014)

More data for this
Ligand-Target Pair
Vascular endothelial growth factor A


(Homo sapiens (Human))
BDBM102348
PNG
(US8536181, A41 | US9278930, A41)
Show SMILES CC(C)(C)OC(=O)N1CCN(Cc2ccn(Cc3ccc(Cl)cc3)c(=O)c2O)CC1
Show InChI InChI=1S/C22H28ClN3O4/c1-22(2,3)30-21(29)25-12-10-24(11-13-25)15-17-8-9-26(20(28)19(17)27)14-16-4-6-18(23)7-5-16/h4-9,27H,10-15H2,1-3H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
AffyNet 
US Patent
n/an/a 1.66E+4n/an/an/an/an/an/a



AERPIO THERAPEUTICS, INC.

US Patent


Assay Description
HEK293 cells are seeded in 96-well poly-lysine coated plates at 20,000 cells per well in DMEM (10% FBS, 1% NEAA, 0.1% glutamine). Following overnight...


US Patent US9278930 (2016)

More data for this
Ligand-Target Pair
Vascular endothelial growth factor A


(Homo sapiens (Human))
BDBM102348
PNG
(US8536181, A41 | US9278930, A41)
Show SMILES CC(C)(C)OC(=O)N1CCN(Cc2ccn(Cc3ccc(Cl)cc3)c(=O)c2O)CC1
Show InChI InChI=1S/C22H28ClN3O4/c1-22(2,3)30-21(29)25-12-10-24(11-13-25)15-17-8-9-26(20(28)19(17)27)14-16-4-6-18(23)7-5-16/h4-9,27H,10-15H2,1-3H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
AffyNet 
US Patent
n/an/a 1.66E+4n/an/an/an/an/an/a



Aerpio Therapeutics Inc.

US Patent


Assay Description
ELISA assay using VEGF.


US Patent US8536181 (2013)

More data for this
Ligand-Target Pair
Vascular endothelial growth factor A


(Homo sapiens (Human))
BDBM102346
PNG
(US8536181, D14 | US9278930, D14)
Show SMILES Cc1ccc(cc1)S(=O)(=O)n1ccc(CN2CCN(CC2)c2ccc(Cl)nn2)c(O)c1=O
Show InChI InChI=1S/C21H22ClN5O4S/c1-15-2-4-17(5-3-15)32(30,31)27-9-8-16(20(28)21(27)29)14-25-10-12-26(13-11-25)19-7-6-18(22)23-24-19/h2-9,28H,10-14H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
AffyNet 
US Patent
n/an/a 1.90E+4n/an/an/an/an/an/a



AERPIO THERAPEUTICS, INC.

US Patent


Assay Description
HEK293 cells are seeded in 96-well poly-lysine coated plates at 20,000 cells per well in DMEM (10% FBS, 1% NEAA, 0.1% glutamine). Following overnight...


US Patent US9278930 (2016)

More data for this
Ligand-Target Pair
Vascular endothelial growth factor A


(Homo sapiens (Human))
BDBM102346
PNG
(US8536181, D14 | US9278930, D14)
Show SMILES Cc1ccc(cc1)S(=O)(=O)n1ccc(CN2CCN(CC2)c2ccc(Cl)nn2)c(O)c1=O
Show InChI InChI=1S/C21H22ClN5O4S/c1-15-2-4-17(5-3-15)32(30,31)27-9-8-16(20(28)21(27)29)14-25-10-12-26(13-11-25)19-7-6-18(22)23-24-19/h2-9,28H,10-14H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
AffyNet 
US Patent
n/an/a 1.90E+4n/an/an/an/an/an/a



Aerpio Therapeutics Inc.

US Patent


Assay Description
ELISA assay using VEGF.


US Patent US8536181 (2013)

More data for this
Ligand-Target Pair
Vascular endothelial growth factor A


(Homo sapiens (Human))
BDBM102346
PNG
(US8536181, D14 | US9278930, D14)
Show SMILES Cc1ccc(cc1)S(=O)(=O)n1ccc(CN2CCN(CC2)c2ccc(Cl)nn2)c(O)c1=O
Show InChI InChI=1S/C21H22ClN5O4S/c1-15-2-4-17(5-3-15)32(30,31)27-9-8-16(20(28)21(27)29)14-25-10-12-26(13-11-25)19-7-6-18(22)23-24-19/h2-9,28H,10-14H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
AffyNet 
US Patent
n/an/a 1.90E+4n/an/an/an/an/an/a



Aerpio Therapeutics Inc.

US Patent


Assay Description
HEK293 cells are seeded in 96-well poly-lysine coated plates at 20,000 cells per well in DMEM (10% FBS, 1% NEAA, 0.1% glutamine). Following overnight...


US Patent US8778412 (2014)

More data for this
Ligand-Target Pair
Vascular endothelial growth factor A


(Homo sapiens (Human))
BDBM102338
PNG
(US8536181, C14 | US9278930, C14)
Show SMILES CC(NCc1ccn(Cc2ccccc2)c(=O)c1O)c1ccccc1
Show InChI InChI=1S/C21H22N2O2/c1-16(18-10-6-3-7-11-18)22-14-19-12-13-23(21(25)20(19)24)15-17-8-4-2-5-9-17/h2-13,16,22,24H,14-15H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
US Patent
n/an/a 2.06E+4n/an/an/an/an/an/a



Aerpio Therapeutics Inc.

US Patent


Assay Description
ELISA assay using VEGF.


US Patent US8536181 (2013)

More data for this
Ligand-Target Pair
Vascular endothelial growth factor A


(Homo sapiens (Human))
BDBM102338
PNG
(US8536181, C14 | US9278930, C14)
Show SMILES CC(NCc1ccn(Cc2ccccc2)c(=O)c1O)c1ccccc1
Show InChI InChI=1S/C21H22N2O2/c1-16(18-10-6-3-7-11-18)22-14-19-12-13-23(21(25)20(19)24)15-17-8-4-2-5-9-17/h2-13,16,22,24H,14-15H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
US Patent
n/an/a 2.06E+4n/an/an/an/an/an/a



AERPIO THERAPEUTICS, INC.

US Patent


Assay Description
HEK293 cells are seeded in 96-well poly-lysine coated plates at 20,000 cells per well in DMEM (10% FBS, 1% NEAA, 0.1% glutamine). Following overnight...


US Patent US9278930 (2016)

More data for this
Ligand-Target Pair
Vascular endothelial growth factor A


(Homo sapiens (Human))
BDBM102338
PNG
(US8536181, C14 | US9278930, C14)
Show SMILES CC(NCc1ccn(Cc2ccccc2)c(=O)c1O)c1ccccc1
Show InChI InChI=1S/C21H22N2O2/c1-16(18-10-6-3-7-11-18)22-14-19-12-13-23(21(25)20(19)24)15-17-8-4-2-5-9-17/h2-13,16,22,24H,14-15H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
US Patent
n/an/a 2.06E+4n/an/an/an/an/an/a



Aerpio Therapeutics Inc.

US Patent


Assay Description
HEK293 cells are seeded in 96-well poly-lysine coated plates at 20,000 cells per well in DMEM (10% FBS, 1% NEAA, 0.1% glutamine). Following overnight...


US Patent US8778412 (2014)

More data for this
Ligand-Target Pair
Vascular endothelial growth factor A


(Homo sapiens (Human))
BDBM102345
PNG
(US8536181, D10 | US9278930, D10)
Show SMILES Cc1ccc(cc1)S(=O)(=O)n1ccc(CN2CCC(CC2)N2CCCCC2)c(O)c1=O
Show InChI InChI=1S/C23H31N3O4S/c1-18-5-7-21(8-6-18)31(29,30)26-16-9-19(22(27)23(26)28)17-24-14-10-20(11-15-24)25-12-3-2-4-13-25/h5-9,16,20,27H,2-4,10-15,17H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
US Patent
n/an/a 2.70E+4n/an/an/an/an/an/a



Aerpio Therapeutics Inc.

US Patent


Assay Description
ELISA assay using VEGF.


US Patent US8536181 (2013)

More data for this
Ligand-Target Pair
Vascular endothelial growth factor A


(Homo sapiens (Human))
BDBM102345
PNG
(US8536181, D10 | US9278930, D10)
Show SMILES Cc1ccc(cc1)S(=O)(=O)n1ccc(CN2CCC(CC2)N2CCCCC2)c(O)c1=O
Show InChI InChI=1S/C23H31N3O4S/c1-18-5-7-21(8-6-18)31(29,30)26-16-9-19(22(27)23(26)28)17-24-14-10-20(11-15-24)25-12-3-2-4-13-25/h5-9,16,20,27H,2-4,10-15,17H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
US Patent
n/an/a 2.70E+4n/an/an/an/an/an/a



Aerpio Therapeutics Inc.

US Patent


Assay Description
HEK293 cells are seeded in 96-well poly-lysine coated plates at 20,000 cells per well in DMEM (10% FBS, 1% NEAA, 0.1% glutamine). Following overnight...


US Patent US8778412 (2014)

More data for this
Ligand-Target Pair
Vascular endothelial growth factor A


(Homo sapiens (Human))
BDBM102345
PNG
(US8536181, D10 | US9278930, D10)
Show SMILES Cc1ccc(cc1)S(=O)(=O)n1ccc(CN2CCC(CC2)N2CCCCC2)c(O)c1=O
Show InChI InChI=1S/C23H31N3O4S/c1-18-5-7-21(8-6-18)31(29,30)26-16-9-19(22(27)23(26)28)17-24-14-10-20(11-15-24)25-12-3-2-4-13-25/h5-9,16,20,27H,2-4,10-15,17H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
US Patent
n/an/a 2.70E+4n/an/an/an/an/an/a



AERPIO THERAPEUTICS, INC.

US Patent


Assay Description
HEK293 cells are seeded in 96-well poly-lysine coated plates at 20,000 cells per well in DMEM (10% FBS, 1% NEAA, 0.1% glutamine). Following overnight...


US Patent US9278930 (2016)

More data for this
Ligand-Target Pair
Vascular endothelial growth factor A


(Homo sapiens (Human))
BDBM102336
PNG
(US8536181, C17 | US9278930, C17)
Show SMILES CC1CCC(CC1)NCc1ccn(Cc2ccccc2)c(=O)c1O
Show InChI InChI=1S/C20H26N2O2/c1-15-7-9-18(10-8-15)21-13-17-11-12-22(20(24)19(17)23)14-16-5-3-2-4-6-16/h2-6,11-12,15,18,21,23H,7-10,13-14H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
US Patent
n/an/a 2.74E+4n/an/an/an/an/an/a



AERPIO THERAPEUTICS, INC.

US Patent


Assay Description
HEK293 cells are seeded in 96-well poly-lysine coated plates at 20,000 cells per well in DMEM (10% FBS, 1% NEAA, 0.1% glutamine). Following overnight...


US Patent US9278930 (2016)

More data for this
Ligand-Target Pair
Vascular endothelial growth factor A


(Homo sapiens (Human))
BDBM102336
PNG
(US8536181, C17 | US9278930, C17)
Show SMILES CC1CCC(CC1)NCc1ccn(Cc2ccccc2)c(=O)c1O
Show InChI InChI=1S/C20H26N2O2/c1-15-7-9-18(10-8-15)21-13-17-11-12-22(20(24)19(17)23)14-16-5-3-2-4-6-16/h2-6,11-12,15,18,21,23H,7-10,13-14H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
US Patent
n/an/a 2.74E+4n/an/an/an/an/an/a



Aerpio Therapeutics Inc.

US Patent


Assay Description
ELISA assay using VEGF.


US Patent US8536181 (2013)

More data for this
Ligand-Target Pair
Vascular endothelial growth factor A


(Homo sapiens (Human))
BDBM102336
PNG
(US8536181, C17 | US9278930, C17)
Show SMILES CC1CCC(CC1)NCc1ccn(Cc2ccccc2)c(=O)c1O
Show InChI InChI=1S/C20H26N2O2/c1-15-7-9-18(10-8-15)21-13-17-11-12-22(20(24)19(17)23)14-16-5-3-2-4-6-16/h2-6,11-12,15,18,21,23H,7-10,13-14H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
US Patent
n/an/a 2.74E+4n/an/an/an/an/an/a



Aerpio Therapeutics Inc.

US Patent


Assay Description
HEK293 cells are seeded in 96-well poly-lysine coated plates at 20,000 cells per well in DMEM (10% FBS, 1% NEAA, 0.1% glutamine). Following overnight...


US Patent US8778412 (2014)

More data for this
Ligand-Target Pair
Vascular endothelial growth factor A


(Homo sapiens (Human))
BDBM102344
PNG
(US8536181, A18 | US9278930, A18)
Show SMILES OCc1ccccc1Cn1ccc(CN2CCCCCC2)c(O)c1=O
Show InChI InChI=1S/C20H26N2O3/c23-15-18-8-4-3-7-16(18)14-22-12-9-17(19(24)20(22)25)13-21-10-5-1-2-6-11-21/h3-4,7-9,12,23-24H,1-2,5-6,10-11,13-15H2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
US Patent
n/an/a 2.92E+4n/an/an/an/an/an/a



Aerpio Therapeutics Inc.

US Patent


Assay Description
HEK293 cells are seeded in 96-well poly-lysine coated plates at 20,000 cells per well in DMEM (10% FBS, 1% NEAA, 0.1% glutamine). Following overnight...


US Patent US8778412 (2014)

More data for this
Ligand-Target Pair
Vascular endothelial growth factor A


(Homo sapiens (Human))
BDBM102344
PNG
(US8536181, A18 | US9278930, A18)
Show SMILES OCc1ccccc1Cn1ccc(CN2CCCCCC2)c(O)c1=O
Show InChI InChI=1S/C20H26N2O3/c23-15-18-8-4-3-7-16(18)14-22-12-9-17(19(24)20(22)25)13-21-10-5-1-2-6-11-21/h3-4,7-9,12,23-24H,1-2,5-6,10-11,13-15H2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
US Patent
n/an/a 2.92E+4n/an/an/an/an/an/a



AERPIO THERAPEUTICS, INC.

US Patent


Assay Description
HEK293 cells are seeded in 96-well poly-lysine coated plates at 20,000 cells per well in DMEM (10% FBS, 1% NEAA, 0.1% glutamine). Following overnight...


US Patent US9278930 (2016)

More data for this
Ligand-Target Pair
Vascular endothelial growth factor A


(Homo sapiens (Human))
BDBM102344
PNG
(US8536181, A18 | US9278930, A18)
Show SMILES OCc1ccccc1Cn1ccc(CN2CCCCCC2)c(O)c1=O
Show InChI InChI=1S/C20H26N2O3/c23-15-18-8-4-3-7-16(18)14-22-12-9-17(19(24)20(22)25)13-21-10-5-1-2-6-11-21/h3-4,7-9,12,23-24H,1-2,5-6,10-11,13-15H2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
US Patent
n/an/a 2.92E+4n/an/an/an/an/an/a



Aerpio Therapeutics Inc.

US Patent


Assay Description
ELISA assay using VEGF.


US Patent US8536181 (2013)

More data for this
Ligand-Target Pair
Vascular endothelial growth factor A


(Homo sapiens (Human))
BDBM102347
PNG
(US8536181, C1 | US9278930, C1)
Show SMILES Oc1c(CNCc2ccccc2)ccn(Cc2ccc(Cl)cc2)c1=O
Show InChI InChI=1S/C20H19ClN2O2/c21-18-8-6-16(7-9-18)14-23-11-10-17(19(24)20(23)25)13-22-12-15-4-2-1-3-5-15/h1-11,22,24H,12-14H2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
US Patent
n/an/a 4.20E+4n/an/an/an/an/an/a



Aerpio Therapeutics Inc.

US Patent


Assay Description
ELISA assay using VEGF.


US Patent US8536181 (2013)

More data for this
Ligand-Target Pair
Vascular endothelial growth factor A


(Homo sapiens (Human))
BDBM102347
PNG
(US8536181, C1 | US9278930, C1)
Show SMILES Oc1c(CNCc2ccccc2)ccn(Cc2ccc(Cl)cc2)c1=O
Show InChI InChI=1S/C20H19ClN2O2/c21-18-8-6-16(7-9-18)14-23-11-10-17(19(24)20(23)25)13-22-12-15-4-2-1-3-5-15/h1-11,22,24H,12-14H2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
US Patent
n/an/a 4.20E+4n/an/an/an/an/an/a



Aerpio Therapeutics Inc.

US Patent


Assay Description
HEK293 cells are seeded in 96-well poly-lysine coated plates at 20,000 cells per well in DMEM (10% FBS, 1% NEAA, 0.1% glutamine). Following overnight...


US Patent US8778412 (2014)

More data for this
Ligand-Target Pair
Vascular endothelial growth factor A


(Homo sapiens (Human))
BDBM102347
PNG
(US8536181, C1 | US9278930, C1)
Show SMILES Oc1c(CNCc2ccccc2)ccn(Cc2ccc(Cl)cc2)c1=O
Show InChI InChI=1S/C20H19ClN2O2/c21-18-8-6-16(7-9-18)14-23-11-10-17(19(24)20(23)25)13-22-12-15-4-2-1-3-5-15/h1-11,22,24H,12-14H2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
US Patent
n/an/a 4.20E+4n/an/an/an/an/an/a



AERPIO THERAPEUTICS, INC.

US Patent


Assay Description
HEK293 cells are seeded in 96-well poly-lysine coated plates at 20,000 cells per well in DMEM (10% FBS, 1% NEAA, 0.1% glutamine). Following overnight...


US Patent US9278930 (2016)

More data for this
Ligand-Target Pair
Vascular endothelial growth factor A


(Homo sapiens (Human))
BDBM102337
PNG
(US8536181, C35 | US9278930, C35)
Show SMILES Oc1c(CNCCCn2ccnc2)ccn(Cc2ccccc2)c1=O
Show InChI InChI=1S/C19H22N4O2/c24-18-17(13-20-8-4-10-22-12-9-21-15-22)7-11-23(19(18)25)14-16-5-2-1-3-6-16/h1-3,5-7,9,11-12,15,20,24H,4,8,10,13-14H2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
AffyNet 
US Patent
n/an/a 4.25E+4n/an/an/an/an/an/a



Aerpio Therapeutics Inc.

US Patent


Assay Description
ELISA assay using VEGF.


US Patent US8536181 (2013)

More data for this
Ligand-Target Pair
Vascular endothelial growth factor A


(Homo sapiens (Human))
BDBM102337
PNG
(US8536181, C35 | US9278930, C35)
Show SMILES Oc1c(CNCCCn2ccnc2)ccn(Cc2ccccc2)c1=O
Show InChI InChI=1S/C19H22N4O2/c24-18-17(13-20-8-4-10-22-12-9-21-15-22)7-11-23(19(18)25)14-16-5-2-1-3-6-16/h1-3,5-7,9,11-12,15,20,24H,4,8,10,13-14H2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
AffyNet 
US Patent
n/an/a 4.25E+4n/an/an/an/an/an/a



Aerpio Therapeutics Inc.

US Patent


Assay Description
HEK293 cells are seeded in 96-well poly-lysine coated plates at 20,000 cells per well in DMEM (10% FBS, 1% NEAA, 0.1% glutamine). Following overnight...


US Patent US8778412 (2014)

More data for this
Ligand-Target Pair
Vascular endothelial growth factor A


(Homo sapiens (Human))
BDBM102337
PNG
(US8536181, C35 | US9278930, C35)
Show SMILES Oc1c(CNCCCn2ccnc2)ccn(Cc2ccccc2)c1=O
Show InChI InChI=1S/C19H22N4O2/c24-18-17(13-20-8-4-10-22-12-9-21-15-22)7-11-23(19(18)25)14-16-5-2-1-3-6-16/h1-3,5-7,9,11-12,15,20,24H,4,8,10,13-14H2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
AffyNet 
US Patent
n/an/a 4.25E+4n/an/an/an/an/an/a



AERPIO THERAPEUTICS, INC.

US Patent


Assay Description
HEK293 cells are seeded in 96-well poly-lysine coated plates at 20,000 cells per well in DMEM (10% FBS, 1% NEAA, 0.1% glutamine). Following overnight...


US Patent US9278930 (2016)

More data for this
Ligand-Target Pair
Vascular endothelial growth factor A


(Homo sapiens (Human))
BDBM126621
PNG
(US8778412, B5 | US9278930, B5)
Show SMILES OCC[C@H]1CCCN1Cc1ccn(Cc2ccccc2)c(=O)c1O
Show InChI InChI=1S/C19H24N2O3/c22-12-9-17-7-4-10-20(17)14-16-8-11-21(19(24)18(16)23)13-15-5-2-1-3-6-15/h1-3,5-6,8,11,17,22-23H,4,7,9-10,12-14H2/t17-/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
US Patent
n/an/a 5.30E+4n/an/an/an/an/an/a



AERPIO THERAPEUTICS, INC.

US Patent


Assay Description
HEK293 cells are seeded in 96-well poly-lysine coated plates at 20,000 cells per well in DMEM (10% FBS, 1% NEAA, 0.1% glutamine). Following overnight...


US Patent US9278930 (2016)

More data for this
Ligand-Target Pair
Vascular endothelial growth factor A


(Homo sapiens (Human))
BDBM102340
PNG
(US8536181, C33 | US9278930, C33)
Show SMILES CSCCNCc1ccn(Cc2ccccc2)c(=O)c1O
Show InChI InChI=1S/C16H20N2O2S/c1-21-10-8-17-11-14-7-9-18(16(20)15(14)19)12-13-5-3-2-4-6-13/h2-7,9,17,19H,8,10-12H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
US Patent
n/an/a 5.30E+4n/an/an/an/an/an/a



AERPIO THERAPEUTICS, INC.

US Patent


Assay Description
HEK293 cells are seeded in 96-well poly-lysine coated plates at 20,000 cells per well in DMEM (10% FBS, 1% NEAA, 0.1% glutamine). Following overnight...


US Patent US9278930 (2016)

More data for this
Ligand-Target Pair
Vascular endothelial growth factor A


(Homo sapiens (Human))
BDBM102340
PNG
(US8536181, C33 | US9278930, C33)
Show SMILES CSCCNCc1ccn(Cc2ccccc2)c(=O)c1O
Show InChI InChI=1S/C16H20N2O2S/c1-21-10-8-17-11-14-7-9-18(16(20)15(14)19)12-13-5-3-2-4-6-13/h2-7,9,17,19H,8,10-12H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
US Patent
n/an/a 5.30E+4n/an/an/an/an/an/a



Aerpio Therapeutics Inc.

US Patent


Assay Description
ELISA assay using VEGF.


US Patent US8536181 (2013)

More data for this
Ligand-Target Pair
Vascular endothelial growth factor A


(Homo sapiens (Human))
BDBM126621
PNG
(US8778412, B5 | US9278930, B5)
Show SMILES OCC[C@H]1CCCN1Cc1ccn(Cc2ccccc2)c(=O)c1O
Show InChI InChI=1S/C19H24N2O3/c22-12-9-17-7-4-10-20(17)14-16-8-11-21(19(24)18(16)23)13-15-5-2-1-3-6-15/h1-3,5-6,8,11,17,22-23H,4,7,9-10,12-14H2/t17-/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
US Patent
n/an/a 5.30E+4n/an/an/an/an/an/a



Aerpio Therapeutics Inc.

US Patent


Assay Description
HEK293 cells are seeded in 96-well poly-lysine coated plates at 20,000 cells per well in DMEM (10% FBS, 1% NEAA, 0.1% glutamine). Following overnight...


US Patent US8778412 (2014)

More data for this
Ligand-Target Pair
Vascular endothelial growth factor A


(Homo sapiens (Human))
BDBM102340
PNG
(US8536181, C33 | US9278930, C33)
Show SMILES CSCCNCc1ccn(Cc2ccccc2)c(=O)c1O
Show InChI InChI=1S/C16H20N2O2S/c1-21-10-8-17-11-14-7-9-18(16(20)15(14)19)12-13-5-3-2-4-6-13/h2-7,9,17,19H,8,10-12H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
US Patent
n/an/a 5.30E+4n/an/an/an/an/an/a



Aerpio Therapeutics Inc.

US Patent


Assay Description
HEK293 cells are seeded in 96-well poly-lysine coated plates at 20,000 cells per well in DMEM (10% FBS, 1% NEAA, 0.1% glutamine). Following overnight...


US Patent US8778412 (2014)

More data for this
Ligand-Target Pair
Vascular endothelial growth factor A


(Homo sapiens (Human))
BDBM102339
PNG
(US8536181, B5)
Show SMILES COC[C@H]1CCCN1Cc1ccn(Cc2ccccc2)c(=O)c1O
Show InChI InChI=1S/C19H24N2O3/c1-24-14-17-8-5-10-20(17)13-16-9-11-21(19(23)18(16)22)12-15-6-3-2-4-7-15/h2-4,6-7,9,11,17,22H,5,8,10,12-14H2,1H3/t17-/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
US Patent
n/an/a 5.30E+4n/an/an/an/an/an/a



Aerpio Therapeutics Inc.

US Patent


Assay Description
ELISA assay using VEGF.


US Patent US8536181 (2013)

More data for this
Ligand-Target Pair
Vascular endothelial growth factor A


(Homo sapiens (Human))
BDBM102342
PNG
(US8536181, C19 | US9278930, C19)
Show SMILES Oc1c(CNC2CCCCNC2=O)ccn(Cc2ccccc2)c1=O
Show InChI InChI=1S/C19H23N3O3/c23-17-15(12-21-16-8-4-5-10-20-18(16)24)9-11-22(19(17)25)13-14-6-2-1-3-7-14/h1-3,6-7,9,11,16,21,23H,4-5,8,10,12-13H2,(H,20,24)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
AffyNet 
US Patent
n/an/a 6.29E+4n/an/an/an/an/an/a



AERPIO THERAPEUTICS, INC.

US Patent


Assay Description
HEK293 cells are seeded in 96-well poly-lysine coated plates at 20,000 cells per well in DMEM (10% FBS, 1% NEAA, 0.1% glutamine). Following overnight...


US Patent US9278930 (2016)

More data for this
Ligand-Target Pair
Vascular endothelial growth factor A


(Homo sapiens (Human))
BDBM102342
PNG
(US8536181, C19 | US9278930, C19)
Show SMILES Oc1c(CNC2CCCCNC2=O)ccn(Cc2ccccc2)c1=O
Show InChI InChI=1S/C19H23N3O3/c23-17-15(12-21-16-8-4-5-10-20-18(16)24)9-11-22(19(17)25)13-14-6-2-1-3-7-14/h1-3,6-7,9,11,16,21,23H,4-5,8,10,12-13H2,(H,20,24)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
AffyNet 
US Patent
n/an/a 6.29E+4n/an/an/an/an/an/a



Aerpio Therapeutics Inc.

US Patent


Assay Description
ELISA assay using VEGF.


US Patent US8536181 (2013)

More data for this
Ligand-Target Pair
Vascular endothelial growth factor A


(Homo sapiens (Human))
BDBM102342
PNG
(US8536181, C19 | US9278930, C19)
Show SMILES Oc1c(CNC2CCCCNC2=O)ccn(Cc2ccccc2)c1=O
Show InChI InChI=1S/C19H23N3O3/c23-17-15(12-21-16-8-4-5-10-20-18(16)24)9-11-22(19(17)25)13-14-6-2-1-3-7-14/h1-3,6-7,9,11,16,21,23H,4-5,8,10,12-13H2,(H,20,24)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
AffyNet 
US Patent
n/an/a 6.29E+4n/an/an/an/an/an/a



Aerpio Therapeutics Inc.

US Patent


Assay Description
HEK293 cells are seeded in 96-well poly-lysine coated plates at 20,000 cells per well in DMEM (10% FBS, 1% NEAA, 0.1% glutamine). Following overnight...


US Patent US8778412 (2014)

More data for this
Ligand-Target Pair
Vascular endothelial growth factor A


(Homo sapiens (Human))
BDBM102341
PNG
(US8536181, B14 | US9278930, B14)
Show SMILES Oc1c(CN2CCN(CC2)c2ccc(Cl)nn2)ccn(Cc2ccccc2)c1=O
Show InChI InChI=1S/C21H22ClN5O2/c22-18-6-7-19(24-23-18)26-12-10-25(11-13-26)15-17-8-9-27(21(29)20(17)28)14-16-4-2-1-3-5-16/h1-9,28H,10-15H2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
AffyNet 
US Patent
n/an/a 7.80E+4n/an/an/an/an/an/a



Aerpio Therapeutics Inc.

US Patent


Assay Description
ELISA assay using VEGF.


US Patent US8536181 (2013)

More data for this
Ligand-Target Pair
Vascular endothelial growth factor A


(Homo sapiens (Human))
BDBM102341
PNG
(US8536181, B14 | US9278930, B14)
Show SMILES Oc1c(CN2CCN(CC2)c2ccc(Cl)nn2)ccn(Cc2ccccc2)c1=O
Show InChI InChI=1S/C21H22ClN5O2/c22-18-6-7-19(24-23-18)26-12-10-25(11-13-26)15-17-8-9-27(21(29)20(17)28)14-16-4-2-1-3-5-16/h1-9,28H,10-15H2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
AffyNet 
US Patent
n/an/a 7.80E+4n/an/an/an/an/an/a



Aerpio Therapeutics Inc.

US Patent


Assay Description
HEK293 cells are seeded in 96-well poly-lysine coated plates at 20,000 cells per well in DMEM (10% FBS, 1% NEAA, 0.1% glutamine). Following overnight...


US Patent US8778412 (2014)

More data for this
Ligand-Target Pair
Vascular endothelial growth factor A


(Homo sapiens (Human))
BDBM102341
PNG
(US8536181, B14 | US9278930, B14)
Show SMILES Oc1c(CN2CCN(CC2)c2ccc(Cl)nn2)ccn(Cc2ccccc2)c1=O
Show InChI InChI=1S/C21H22ClN5O2/c22-18-6-7-19(24-23-18)26-12-10-25(11-13-26)15-17-8-9-27(21(29)20(17)28)14-16-4-2-1-3-5-16/h1-9,28H,10-15H2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
AffyNet 
US Patent
n/an/a 7.80E+4n/an/an/an/an/an/a



AERPIO THERAPEUTICS, INC.

US Patent


Assay Description
HEK293 cells are seeded in 96-well poly-lysine coated plates at 20,000 cells per well in DMEM (10% FBS, 1% NEAA, 0.1% glutamine). Following overnight...


US Patent US9278930 (2016)

More data for this
Ligand-Target Pair
Vascular endothelial growth factor A


(Homo sapiens (Human))
BDBM102351
PNG
(US8536181, F2 | US9278930, F2)
Show SMILES Oc1cccn(Cc2cccc(Cl)c2)c1=O
Show InChI InChI=1S/C12H10ClNO2/c13-10-4-1-3-9(7-10)8-14-6-2-5-11(15)12(14)16/h1-7,15H,8H2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
US Patent
n/an/a>1.00E+5n/an/an/an/an/an/a



Aerpio Therapeutics Inc.

US Patent


Assay Description
ELISA assay using VEGF.


US Patent US8536181 (2013)

More data for this
Ligand-Target Pair
Displayed 1 to 50 (of 131 total )  |  Next  |  Last  >>
Jump to: