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Compile Data Set for Download or QSAR

Found 34 hits Enz. Inhib. hit(s) with Target = 'Vascular endothelial growth factor receptor 2' AND taxid = 7955   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Vascular endothelial growth factor receptor 2


(Danio rerio)
BDBM50429478
PNG
(CHEMBL2331570)
Show SMILES FC(F)(F)c1cccc(NC(=O)Nc2ccc(Oc3ncnc4n[nH]cc34)cc2)c1
Show InChI InChI=1S/C19H13F3N6O2/c20-19(21,22)11-2-1-3-13(8-11)27-18(29)26-12-4-6-14(7-5-12)30-17-15-9-25-28-16(15)23-10-24-17/h1-10H,(H2,26,27,29)(H,23,24,25,28)
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n/an/a 1.05E+3n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 in transgenic zebrafish embryo assessed as inhibition of intersegmental vessels formation measured 33 hrs post fertilization by ...


J Med Chem 56: 1641-55 (2013)

More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Danio rerio)
BDBM50429479
PNG
(CHEMBL2332849)
Show SMILES FC(F)(F)c1ccc(NC(=O)Nc2ccc(Oc3ncnc4n[nH]cc34)cc2)cc1
Show InChI InChI=1S/C19H13F3N6O2/c20-19(21,22)11-1-3-12(4-2-11)26-18(29)27-13-5-7-14(8-6-13)30-17-15-9-25-28-16(15)23-10-24-17/h1-10H,(H2,26,27,29)(H,23,24,25,28)
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n/an/a 1.20E+3n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 in transgenic zebrafish embryo assessed as inhibition of intersegmental vessels formation measured 33 hrs post fertilization by ...


J Med Chem 56: 1641-55 (2013)

More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Danio rerio)
BDBM50429477
PNG
(CHEMBL2332840)
Show SMILES FC(F)(F)c1cc(NC(=O)Nc2ccc(Oc3ncnc4n[nH]cc34)cc2)ccc1Cl
Show InChI InChI=1S/C19H12ClF3N6O2/c20-15-6-3-11(7-14(15)19(21,22)23)28-18(30)27-10-1-4-12(5-2-10)31-17-13-8-26-29-16(13)24-9-25-17/h1-9H,(H2,27,28,30)(H,24,25,26,29)
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n/an/a 2.25E+3n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 in transgenic zebrafish embryo assessed as inhibition of intersegmental vessels formation measured 33 hrs post fertilization by ...


J Med Chem 56: 1641-55 (2013)

More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Danio rerio)
BDBM16673
PNG
(4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamo...)
Show SMILES CNC(=O)c1cc(Oc2ccc(NC(=O)Nc3ccc(Cl)c(c3)C(F)(F)F)cc2)ccn1
Show InChI InChI=1S/C21H16ClF3N4O3/c1-26-19(30)18-11-15(8-9-27-18)32-14-5-2-12(3-6-14)28-20(31)29-13-4-7-17(22)16(10-13)21(23,24)25/h2-11H,1H3,(H,26,30)(H2,28,29,31)
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n/an/a 2.60E+3n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 in transgenic zebrafish embryo assessed as inhibition of intersegmental vessels formation measured 33 hrs post fertilization by ...


J Med Chem 56: 1641-55 (2013)

More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Danio rerio)
BDBM50429481
PNG
(CHEMBL2332870)
Show SMILES FC(F)(F)c1cc(NC(=O)Nc2ccc(Oc3ncnc4n[nH]cc34)cc2)cc(c1)C(F)(F)F
Show InChI InChI=1S/C20H12F6N6O2/c21-19(22,23)10-5-11(20(24,25)26)7-13(6-10)31-18(33)30-12-1-3-14(4-2-12)34-17-15-8-29-32-16(15)27-9-28-17/h1-9H,(H2,30,31,33)(H,27,28,29,32)
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n/an/a 5.18E+3n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 in transgenic zebrafish embryo assessed as inhibition of intersegmental vessels formation measured 33 hrs post fertilization by ...


J Med Chem 56: 1641-55 (2013)

More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Danio rerio)
BDBM50429484
PNG
(CHEMBL2332867)
Show SMILES CC(C)c1cccc(NC(=O)Nc2ccc(Oc3ncnc4n[nH]cc34)cc2)c1
Show InChI InChI=1S/C21H20N6O2/c1-13(2)14-4-3-5-16(10-14)26-21(28)25-15-6-8-17(9-7-15)29-20-18-11-24-27-19(18)22-12-23-20/h3-13H,1-2H3,(H2,25,26,28)(H,22,23,24,27)
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n/an/a 7.73E+3n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 in transgenic zebrafish embryo assessed as inhibition of intersegmental vessels formation measured 33 hrs post fertilization by ...


J Med Chem 56: 1641-55 (2013)

More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Danio rerio)
BDBM50429480
PNG
(CHEMBL2332871)
Show SMILES FC(F)(F)c1ccc(NC(=O)Nc2ccc(Oc3ncnc4n[nH]cc34)cc2)c(Cl)c1
Show InChI InChI=1S/C19H12ClF3N6O2/c20-14-7-10(19(21,22)23)1-6-15(14)28-18(30)27-11-2-4-12(5-3-11)31-17-13-8-26-29-16(13)24-9-25-17/h1-9H,(H2,27,28,30)(H,24,25,26,29)
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n/an/a 8.46E+3n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 in transgenic zebrafish embryo assessed as inhibition of intersegmental vessels formation measured 33 hrs post fertilization by ...


J Med Chem 56: 1641-55 (2013)

More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Danio rerio)
BDBM50429483
PNG
(CHEMBL2332868)
Show SMILES Fc1cccc(NC(=O)Nc2ccc(Oc3ncnc4n[nH]cc34)cc2)c1
Show InChI InChI=1S/C18H13FN6O2/c19-11-2-1-3-13(8-11)24-18(26)23-12-4-6-14(7-5-12)27-17-15-9-22-25-16(15)20-10-21-17/h1-10H,(H2,23,24,26)(H,20,21,22,25)
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n/an/a 1.66E+4n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 in transgenic zebrafish embryo assessed as inhibition of intersegmental vessels formation measured 33 hrs post fertilization by ...


J Med Chem 56: 1641-55 (2013)

More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Danio rerio)
BDBM50429482
PNG
(CHEMBL2332869)
Show SMILES FC(F)(F)Oc1cccc(NC(=O)Nc2ccc(Oc3ncnc4n[nH]cc34)cc2)c1
Show InChI InChI=1S/C19H13F3N6O3/c20-19(21,22)31-14-3-1-2-12(8-14)27-18(29)26-11-4-6-13(7-5-11)30-17-15-9-25-28-16(15)23-10-24-17/h1-10H,(H2,26,27,29)(H,23,24,25,28)
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n/an/a 1.78E+4n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 in transgenic zebrafish embryo assessed as inhibition of intersegmental vessels formation measured 33 hrs post fertilization by ...


J Med Chem 56: 1641-55 (2013)

More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Danio rerio)
BDBM50429491
PNG
(CHEMBL2332860)
Show SMILES O=C(Nc1ccccc1)Nc1ccc(Oc2ncnc3n[nH]cc23)cc1
Show InChI InChI=1S/C18H14N6O2/c25-18(22-12-4-2-1-3-5-12)23-13-6-8-14(9-7-13)26-17-15-10-21-24-16(15)19-11-20-17/h1-11H,(H2,22,23,25)(H,19,20,21,24)
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n/an/a 2.02E+4n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 in transgenic zebrafish embryo assessed as inhibition of intersegmental vessels formation measured 33 hrs post fertilization by ...


J Med Chem 56: 1641-55 (2013)

More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Danio rerio)
BDBM50429493
PNG
(CHEMBL2332858)
Show SMILES Brc1ccc(cc1)C(=O)Nc1ccc(Oc2ncnc3n[nH]cc23)cc1
Show InChI InChI=1S/C18H12BrN5O2/c19-12-3-1-11(2-4-12)17(25)23-13-5-7-14(8-6-13)26-18-15-9-22-24-16(15)20-10-21-18/h1-10H,(H,23,25)(H,20,21,22,24)
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n/an/a 7.47E+4n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 in transgenic zebrafish embryo assessed as inhibition of intersegmental vessels formation measured 33 hrs post fertilization by ...


J Med Chem 56: 1641-55 (2013)

More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Danio rerio)
BDBM50429503
PNG
(CHEMBL2332847)
Show SMILES Brc1ccc(NC(=O)Nc2ccc(Oc3ncnc4n[nH]cc34)cc2)cc1
Show InChI InChI=1S/C18H13BrN6O2/c19-11-1-3-12(4-2-11)23-18(26)24-13-5-7-14(8-6-13)27-17-15-9-22-25-16(15)20-10-21-17/h1-10H,(H2,23,24,26)(H,20,21,22,25)
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n/an/a 7.47E+4n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 in transgenic zebrafish embryo assessed as inhibition of intersegmental vessels formation measured 33 hrs post fertilization by ...


J Med Chem 56: 1641-55 (2013)

More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Danio rerio)
BDBM50429492
PNG
(CHEMBL2332859)
Show SMILES Brc1ccc(CC(=O)Nc2ccc(Oc3ncnc4n[nH]cc34)cc2)cc1
Show InChI InChI=1S/C19H14BrN5O2/c20-13-3-1-12(2-4-13)9-17(26)24-14-5-7-15(8-6-14)27-19-16-10-23-25-18(16)21-11-22-19/h1-8,10-11H,9H2,(H,24,26)(H,21,22,23,25)
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n/an/a 7.47E+4n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 in transgenic zebrafish embryo assessed as inhibition of intersegmental vessels formation measured 33 hrs post fertilization by ...


J Med Chem 56: 1641-55 (2013)

More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Danio rerio)
BDBM50429504
PNG
(CHEMBL2332846)
Show SMILES COc1cccc(NC(=O)Nc2ccc(Oc3ncnc4n[nH]cc34)cc2)c1
Show InChI InChI=1S/C19H16N6O3/c1-27-15-4-2-3-13(9-15)24-19(26)23-12-5-7-14(8-6-12)28-18-16-10-22-25-17(16)20-11-21-18/h2-11H,1H3,(H2,23,24,26)(H,20,21,22,25)
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n/an/a 8.20E+4n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 in transgenic zebrafish embryo assessed as inhibition of intersegmental vessels formation measured 33 hrs post fertilization by ...


J Med Chem 56: 1641-55 (2013)

More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Danio rerio)
BDBM50429486
PNG
(CHEMBL2332865)
Show SMILES Fc1ccc(NC(=O)Nc2ccc(Oc3ncnc4n[nH]cc34)cc2)cc1
Show InChI InChI=1S/C18H13FN6O2/c19-11-1-3-12(4-2-11)23-18(26)24-13-5-7-14(8-6-13)27-17-15-9-22-25-16(15)20-10-21-17/h1-10H,(H2,23,24,26)(H,20,21,22,25)
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n/an/a 8.94E+4n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 in transgenic zebrafish embryo assessed as inhibition of intersegmental vessels formation measured 33 hrs post fertilization by ...


J Med Chem 56: 1641-55 (2013)

More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Danio rerio)
BDBM50429489
PNG
(CHEMBL2332862)
Show SMILES CC(NC(=O)Nc1ccc(Oc2ncnc3n[nH]cc23)cc1)c1ccccc1
Show InChI InChI=1S/C20H18N6O2/c1-13(14-5-3-2-4-6-14)24-20(27)25-15-7-9-16(10-8-15)28-19-17-11-23-26-18(17)21-12-22-19/h2-13H,1H3,(H2,24,25,27)(H,21,22,23,26)
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n/an/a>9.82E+4n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 in transgenic zebrafish embryo assessed as inhibition of intersegmental vessels formation measured 33 hrs post fertilization by ...


J Med Chem 56: 1641-55 (2013)

More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Danio rerio)
BDBM50429502
PNG
(CHEMBL2332848)
Show SMILES Cc1cccc(NC(=O)Nc2ccc(Oc3ncnc4n[nH]cc34)cc2)c1C
Show InChI InChI=1S/C20H18N6O2/c1-12-4-3-5-17(13(12)2)25-20(27)24-14-6-8-15(9-7-14)28-19-16-10-23-26-18(16)21-11-22-19/h3-11H,1-2H3,(H2,24,25,27)(H,21,22,23,26)
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n/an/a 9.88E+4n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 in transgenic zebrafish embryo assessed as inhibition of intersegmental vessels formation measured 33 hrs post fertilization by ...


J Med Chem 56: 1641-55 (2013)

More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Danio rerio)
BDBM50429495
PNG
(CHEMBL2332856)
Show SMILES FC(F)(F)c1ccc(cc1)C(=O)Nc1cccc(Oc2ncnc3n[nH]cc23)c1
Show InChI InChI=1S/C19H12F3N5O2/c20-19(21,22)12-6-4-11(5-7-12)17(28)26-13-2-1-3-14(8-13)29-18-15-9-25-27-16(15)23-10-24-18/h1-10H,(H,26,28)(H,23,24,25,27)
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n/an/a>1.00E+5n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 in transgenic zebrafish embryo assessed as inhibition of intersegmental vessels formation measured 33 hrs post fertilization by ...


J Med Chem 56: 1641-55 (2013)

More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Danio rerio)
BDBM50429496
PNG
(CHEMBL2332855)
Show SMILES Brc1ccc(CC(=O)Nc2cccc(Oc3ncnc4n[nH]cc34)c2)cc1
Show InChI InChI=1S/C19H14BrN5O2/c20-13-6-4-12(5-7-13)8-17(26)24-14-2-1-3-15(9-14)27-19-16-10-23-25-18(16)21-11-22-19/h1-7,9-11H,8H2,(H,24,26)(H,21,22,23,25)
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n/an/a>1.00E+5n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 in transgenic zebrafish embryo assessed as inhibition of intersegmental vessels formation measured 33 hrs post fertilization by ...


J Med Chem 56: 1641-55 (2013)

More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Danio rerio)
BDBM50429497
PNG
(CHEMBL2332854)
Show SMILES FC(F)(F)c1ccc(CC(=O)Nc2cccc(Oc3ncnc4n[nH]cc34)c2)cc1
Show InChI InChI=1S/C20H14F3N5O2/c21-20(22,23)13-6-4-12(5-7-13)8-17(29)27-14-2-1-3-15(9-14)30-19-16-10-26-28-18(16)24-11-25-19/h1-7,9-11H,8H2,(H,27,29)(H,24,25,26,28)
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n/an/a>1.00E+5n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 in transgenic zebrafish embryo assessed as inhibition of intersegmental vessels formation measured 33 hrs post fertilization by ...


J Med Chem 56: 1641-55 (2013)

More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Danio rerio)
BDBM50429498
PNG
(CHEMBL2332853)
Show SMILES Brc1ccc(NC(=O)Nc2cccc(Oc3ncnc4n[nH]cc34)c2)cc1
Show InChI InChI=1S/C18H13BrN6O2/c19-11-4-6-12(7-5-11)23-18(26)24-13-2-1-3-14(8-13)27-17-15-9-22-25-16(15)20-10-21-17/h1-10H,(H2,23,24,26)(H,20,21,22,25)
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n/an/a>1.00E+5n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 in transgenic zebrafish embryo assessed as inhibition of intersegmental vessels formation measured 33 hrs post fertilization by ...


J Med Chem 56: 1641-55 (2013)

More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Danio rerio)
BDBM50429499
PNG
(CHEMBL2332852)
Show SMILES FC(F)(F)c1ccc(NC(=O)Nc2cccc(Oc3ncnc4n[nH]cc34)c2)cc1
Show InChI InChI=1S/C19H13F3N6O2/c20-19(21,22)11-4-6-12(7-5-11)26-18(29)27-13-2-1-3-14(8-13)30-17-15-9-25-28-16(15)23-10-24-17/h1-10H,(H2,26,27,29)(H,23,24,25,28)
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n/an/a>1.00E+5n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 in transgenic zebrafish embryo assessed as inhibition of intersegmental vessels formation measured 33 hrs post fertilization by ...


J Med Chem 56: 1641-55 (2013)

More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Danio rerio)
BDBM50429487
PNG
(CHEMBL2332864)
Show SMILES O=C(NCC1CCCCC1)Nc1ccc(Oc2ncnc3n[nH]cc23)cc1
Show InChI InChI=1S/C19H22N6O2/c26-19(20-10-13-4-2-1-3-5-13)24-14-6-8-15(9-7-14)27-18-16-11-23-25-17(16)21-12-22-18/h6-9,11-13H,1-5,10H2,(H2,20,24,26)(H,21,22,23,25)
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n/an/a>1.00E+5n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 in transgenic zebrafish embryo assessed as inhibition of intersegmental vessels formation measured 33 hrs post fertilization by ...


J Med Chem 56: 1641-55 (2013)

More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Danio rerio)
BDBM50429501
PNG
(CHEMBL2332850)
Show SMILES COc1cccc(NC(=O)Nc2ccc(Oc3ncnc4n(C)ncc34)cc2)c1
Show InChI InChI=1S/C20H18N6O3/c1-26-18-17(11-23-26)19(22-12-21-18)29-15-8-6-13(7-9-15)24-20(27)25-14-4-3-5-16(10-14)28-2/h3-12H,1-2H3,(H2,24,25,27)
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n/an/a>1.00E+5n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 in transgenic zebrafish embryo assessed as inhibition of intersegmental vessels formation measured 33 hrs post fertilization by ...


J Med Chem 56: 1641-55 (2013)

More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Danio rerio)
BDBM50429485
PNG
(CHEMBL2332866)
Show SMILES O=C(Nc1ccc(Oc2ncnc3n[nH]cc23)cc1)Nc1ccc(cc1)N1CCOCC1
Show InChI InChI=1S/C22H21N7O3/c30-22(26-15-1-5-17(6-2-15)29-9-11-31-12-10-29)27-16-3-7-18(8-4-16)32-21-19-13-25-28-20(19)23-14-24-21/h1-8,13-14H,9-12H2,(H2,26,27,30)(H,23,24,25,28)
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n/an/a>1.00E+5n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 in transgenic zebrafish embryo assessed as inhibition of intersegmental vessels formation measured 33 hrs post fertilization by ...


J Med Chem 56: 1641-55 (2013)

More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Danio rerio)
BDBM50429508
PNG
(CHEMBL2332842)
Show SMILES Brc1ccc(NC(=O)Nc2ccc(Nc3ncnc4n[nH]cc34)cc2)cc1
Show InChI InChI=1S/C18H14BrN7O/c19-11-1-3-13(4-2-11)24-18(27)25-14-7-5-12(6-8-14)23-16-15-9-22-26-17(15)21-10-20-16/h1-10H,(H2,24,25,27)(H2,20,21,22,23,26)
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n/an/a>1.00E+5n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 in transgenic zebrafish embryo assessed as inhibition of intersegmental vessels formation measured 33 hrs post fertilization by ...


J Med Chem 56: 1641-55 (2013)

More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Danio rerio)
BDBM50429505
PNG
(CHEMBL2332845)
Show SMILES CC(NC(=O)Nc1ccc(Nc2ncnc3n[nH]cc23)cc1)c1ccccc1
Show InChI InChI=1S/C20H19N7O/c1-13(14-5-3-2-4-6-14)24-20(28)26-16-9-7-15(8-10-16)25-18-17-11-23-27-19(17)22-12-21-18/h2-13H,1H3,(H2,24,26,28)(H2,21,22,23,25,27)
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n/an/a>1.00E+5n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 in transgenic zebrafish embryo assessed as inhibition of intersegmental vessels formation measured 33 hrs post fertilization by ...


J Med Chem 56: 1641-55 (2013)

More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Danio rerio)
BDBM50429506
PNG
(CHEMBL2332844)
Show SMILES FC(F)(F)c1ccc(NC(=O)Nc2ccc(Nc3ncnc4n[nH]cc34)cc2)cc1
Show InChI InChI=1S/C19H14F3N7O/c20-19(21,22)11-1-3-13(4-2-11)27-18(30)28-14-7-5-12(6-8-14)26-16-15-9-25-29-17(15)24-10-23-16/h1-10H,(H2,27,28,30)(H2,23,24,25,26,29)
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n/an/a>1.00E+5n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 in transgenic zebrafish embryo assessed as inhibition of intersegmental vessels formation measured 33 hrs post fertilization by ...


J Med Chem 56: 1641-55 (2013)

More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Danio rerio)
BDBM50429488
PNG
(CHEMBL2332863)
Show SMILES O=C(NC1CCCCC1)Nc1ccc(Oc2ncnc3n[nH]cc23)cc1
Show InChI InChI=1S/C18H20N6O2/c25-18(22-12-4-2-1-3-5-12)23-13-6-8-14(9-7-13)26-17-15-10-21-24-16(15)19-11-20-17/h6-12H,1-5H2,(H2,22,23,25)(H,19,20,21,24)
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n/an/a>1.00E+5n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 in transgenic zebrafish embryo assessed as inhibition of intersegmental vessels formation measured 33 hrs post fertilization by ...


J Med Chem 56: 1641-55 (2013)

More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Danio rerio)
BDBM50429494
PNG
(CHEMBL2332857)
Show SMILES Brc1ccc(cc1)C(=O)Nc1cccc(Oc2ncnc3n[nH]cc23)c1
Show InChI InChI=1S/C18H12BrN5O2/c19-12-6-4-11(5-7-12)17(25)23-13-2-1-3-14(8-13)26-18-15-9-22-24-16(15)20-10-21-18/h1-10H,(H,23,25)(H,20,21,22,24)
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n/an/a>1.00E+5n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 in transgenic zebrafish embryo assessed as inhibition of intersegmental vessels formation measured 33 hrs post fertilization by ...


J Med Chem 56: 1641-55 (2013)

More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Danio rerio)
BDBM50429509
PNG
(CHEMBL2332841)
Show SMILES COc1cccc(NC(=O)Nc2ccc(Nc3ncnc4n[nH]cc34)cc2)c1
Show InChI InChI=1S/C19H17N7O2/c1-28-15-4-2-3-14(9-15)25-19(27)24-13-7-5-12(6-8-13)23-17-16-10-22-26-18(16)21-11-20-17/h2-11H,1H3,(H2,24,25,27)(H2,20,21,22,23,26)
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n/an/a>1.00E+5n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 in transgenic zebrafish embryo assessed as inhibition of intersegmental vessels formation measured 33 hrs post fertilization by ...


J Med Chem 56: 1641-55 (2013)

More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Danio rerio)
BDBM50429507
PNG
(CHEMBL2332843)
Show SMILES Cc1cccc(NC(=O)Nc2ccc(Nc3ncnc4n[nH]cc34)cc2)c1C
Show InChI InChI=1S/C20H19N7O/c1-12-4-3-5-17(13(12)2)26-20(28)25-15-8-6-14(7-9-15)24-18-16-10-23-27-19(16)22-11-21-18/h3-11H,1-2H3,(H2,25,26,28)(H2,21,22,23,24,27)
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n/an/a>1.00E+5n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 in transgenic zebrafish embryo assessed as inhibition of intersegmental vessels formation measured 33 hrs post fertilization by ...


J Med Chem 56: 1641-55 (2013)

More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Danio rerio)
BDBM50429490
PNG
(CHEMBL2332861)
Show SMILES O=C(Nc1ccc(Oc2ncnc3n[nH]cc23)cc1)Nc1cccnc1
Show InChI InChI=1S/C17H13N7O2/c25-17(23-12-2-1-7-18-8-12)22-11-3-5-13(6-4-11)26-16-14-9-21-24-15(14)19-10-20-16/h1-10H,(H2,22,23,25)(H,19,20,21,24)
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n/an/a>1.00E+5n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 in transgenic zebrafish embryo assessed as inhibition of intersegmental vessels formation measured 33 hrs post fertilization by ...


J Med Chem 56: 1641-55 (2013)

More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Danio rerio)
BDBM50429500
PNG
(CHEMBL2332851)
Show SMILES Cn1ncc2c(Oc3ccc(NC(=O)Nc4ccc(cc4)C(F)(F)F)cc3)ncnc12
Show InChI InChI=1S/C20H15F3N6O2/c1-29-17-16(10-26-29)18(25-11-24-17)31-15-8-6-14(7-9-15)28-19(30)27-13-4-2-12(3-5-13)20(21,22)23/h2-11H,1H3,(H2,27,28,30)
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n/an/a>1.00E+5n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 in transgenic zebrafish embryo assessed as inhibition of intersegmental vessels formation measured 33 hrs post fertilization by ...


J Med Chem 56: 1641-55 (2013)

More data for this
Ligand-Target Pair