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Found 34 hits Enz. Inhib. hit(s) with Target = 'Vascular endothelial growth factor receptor 2' AND taxid = 7955   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Vascular endothelial growth factor receptor 2


(Danio rerio)
BDBM50429478
PNG
(CHEMBL2331570)
Show SMILES FC(F)(F)c1cccc(NC(=O)Nc2ccc(Oc3ncnc4n[nH]cc34)cc2)c1
Show InChI InChI=1S/C19H13F3N6O2/c20-19(21,22)11-2-1-3-13(8-11)27-18(29)26-12-4-6-14(7-5-12)30-17-15-9-25-28-16(15)23-10-24-17/h1-10H,(H2,26,27,29)(H,23,24,25,28)
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n/an/a 1.05E+3n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 in transgenic zebrafish embryo assessed as inhibition of intersegmental vessels formation measured 33 hrs post fertilization by ...


Citation and Details
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Danio rerio)
BDBM50429479
PNG
(CHEMBL2332849)
Show SMILES FC(F)(F)c1ccc(NC(=O)Nc2ccc(Oc3ncnc4n[nH]cc34)cc2)cc1
Show InChI InChI=1S/C19H13F3N6O2/c20-19(21,22)11-1-3-12(4-2-11)26-18(29)27-13-5-7-14(8-6-13)30-17-15-9-25-28-16(15)23-10-24-17/h1-10H,(H2,26,27,29)(H,23,24,25,28)
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n/an/a 1.20E+3n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 in transgenic zebrafish embryo assessed as inhibition of intersegmental vessels formation measured 33 hrs post fertilization by ...


Citation and Details
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Danio rerio)
BDBM50429477
PNG
(CHEMBL2332840)
Show SMILES FC(F)(F)c1cc(NC(=O)Nc2ccc(Oc3ncnc4n[nH]cc34)cc2)ccc1Cl
Show InChI InChI=1S/C19H12ClF3N6O2/c20-15-6-3-11(7-14(15)19(21,22)23)28-18(30)27-10-1-4-12(5-2-10)31-17-13-8-26-29-16(13)24-9-25-17/h1-9H,(H2,27,28,30)(H,24,25,26,29)
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n/an/a 2.25E+3n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 in transgenic zebrafish embryo assessed as inhibition of intersegmental vessels formation measured 33 hrs post fertilization by ...


Citation and Details
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Danio rerio)
BDBM16673
PNG
(4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamo...)
Show SMILES CNC(=O)c1cc(Oc2ccc(NC(=O)Nc3ccc(Cl)c(c3)C(F)(F)F)cc2)ccn1
Show InChI InChI=1S/C21H16ClF3N4O3/c1-26-19(30)18-11-15(8-9-27-18)32-14-5-2-12(3-6-14)28-20(31)29-13-4-7-17(22)16(10-13)21(23,24)25/h2-11H,1H3,(H,26,30)(H2,28,29,31)
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n/an/a 2.60E+3n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 in transgenic zebrafish embryo assessed as inhibition of intersegmental vessels formation measured 33 hrs post fertilization by ...


Citation and Details
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Danio rerio)
BDBM50429481
PNG
(CHEMBL2332870)
Show SMILES FC(F)(F)c1cc(NC(=O)Nc2ccc(Oc3ncnc4n[nH]cc34)cc2)cc(c1)C(F)(F)F
Show InChI InChI=1S/C20H12F6N6O2/c21-19(22,23)10-5-11(20(24,25)26)7-13(6-10)31-18(33)30-12-1-3-14(4-2-12)34-17-15-8-29-32-16(15)27-9-28-17/h1-9H,(H2,30,31,33)(H,27,28,29,32)
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n/an/a 5.18E+3n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 in transgenic zebrafish embryo assessed as inhibition of intersegmental vessels formation measured 33 hrs post fertilization by ...


Citation and Details
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Danio rerio)
BDBM50429484
PNG
(CHEMBL2332867)
Show SMILES CC(C)c1cccc(NC(=O)Nc2ccc(Oc3ncnc4n[nH]cc34)cc2)c1
Show InChI InChI=1S/C21H20N6O2/c1-13(2)14-4-3-5-16(10-14)26-21(28)25-15-6-8-17(9-7-15)29-20-18-11-24-27-19(18)22-12-23-20/h3-13H,1-2H3,(H2,25,26,28)(H,22,23,24,27)
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n/an/a 7.73E+3n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 in transgenic zebrafish embryo assessed as inhibition of intersegmental vessels formation measured 33 hrs post fertilization by ...


Citation and Details
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Danio rerio)
BDBM50429480
PNG
(CHEMBL2332871)
Show SMILES FC(F)(F)c1ccc(NC(=O)Nc2ccc(Oc3ncnc4n[nH]cc34)cc2)c(Cl)c1
Show InChI InChI=1S/C19H12ClF3N6O2/c20-14-7-10(19(21,22)23)1-6-15(14)28-18(30)27-11-2-4-12(5-3-11)31-17-13-8-26-29-16(13)24-9-25-17/h1-9H,(H2,27,28,30)(H,24,25,26,29)
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n/an/a 8.46E+3n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 in transgenic zebrafish embryo assessed as inhibition of intersegmental vessels formation measured 33 hrs post fertilization by ...


Citation and Details
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Danio rerio)
BDBM50429483
PNG
(CHEMBL2332868)
Show SMILES Fc1cccc(NC(=O)Nc2ccc(Oc3ncnc4n[nH]cc34)cc2)c1
Show InChI InChI=1S/C18H13FN6O2/c19-11-2-1-3-13(8-11)24-18(26)23-12-4-6-14(7-5-12)27-17-15-9-22-25-16(15)20-10-21-17/h1-10H,(H2,23,24,26)(H,20,21,22,25)
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n/an/a 1.66E+4n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 in transgenic zebrafish embryo assessed as inhibition of intersegmental vessels formation measured 33 hrs post fertilization by ...


Citation and Details
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Danio rerio)
BDBM50429482
PNG
(CHEMBL2332869)
Show SMILES FC(F)(F)Oc1cccc(NC(=O)Nc2ccc(Oc3ncnc4n[nH]cc34)cc2)c1
Show InChI InChI=1S/C19H13F3N6O3/c20-19(21,22)31-14-3-1-2-12(8-14)27-18(29)26-11-4-6-13(7-5-11)30-17-15-9-25-28-16(15)23-10-24-17/h1-10H,(H2,26,27,29)(H,23,24,25,28)
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n/an/a 1.78E+4n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 in transgenic zebrafish embryo assessed as inhibition of intersegmental vessels formation measured 33 hrs post fertilization by ...


Citation and Details
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Danio rerio)
BDBM50429491
PNG
(CHEMBL2332860)
Show SMILES O=C(Nc1ccccc1)Nc1ccc(Oc2ncnc3n[nH]cc23)cc1
Show InChI InChI=1S/C18H14N6O2/c25-18(22-12-4-2-1-3-5-12)23-13-6-8-14(9-7-13)26-17-15-10-21-24-16(15)19-11-20-17/h1-11H,(H2,22,23,25)(H,19,20,21,24)
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n/an/a 2.02E+4n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 in transgenic zebrafish embryo assessed as inhibition of intersegmental vessels formation measured 33 hrs post fertilization by ...


Citation and Details
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Danio rerio)
BDBM50429493
PNG
(CHEMBL2332858)
Show SMILES Brc1ccc(cc1)C(=O)Nc1ccc(Oc2ncnc3n[nH]cc23)cc1
Show InChI InChI=1S/C18H12BrN5O2/c19-12-3-1-11(2-4-12)17(25)23-13-5-7-14(8-6-13)26-18-15-9-22-24-16(15)20-10-21-18/h1-10H,(H,23,25)(H,20,21,22,24)
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n/an/a 7.47E+4n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 in transgenic zebrafish embryo assessed as inhibition of intersegmental vessels formation measured 33 hrs post fertilization by ...


Citation and Details
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Danio rerio)
BDBM50429503
PNG
(CHEMBL2332847)
Show SMILES Brc1ccc(NC(=O)Nc2ccc(Oc3ncnc4n[nH]cc34)cc2)cc1
Show InChI InChI=1S/C18H13BrN6O2/c19-11-1-3-12(4-2-11)23-18(26)24-13-5-7-14(8-6-13)27-17-15-9-22-25-16(15)20-10-21-17/h1-10H,(H2,23,24,26)(H,20,21,22,25)
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n/an/a 7.47E+4n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 in transgenic zebrafish embryo assessed as inhibition of intersegmental vessels formation measured 33 hrs post fertilization by ...


Citation and Details
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Danio rerio)
BDBM50429492
PNG
(CHEMBL2332859)
Show SMILES Brc1ccc(CC(=O)Nc2ccc(Oc3ncnc4n[nH]cc34)cc2)cc1
Show InChI InChI=1S/C19H14BrN5O2/c20-13-3-1-12(2-4-13)9-17(26)24-14-5-7-15(8-6-14)27-19-16-10-23-25-18(16)21-11-22-19/h1-8,10-11H,9H2,(H,24,26)(H,21,22,23,25)
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n/an/a 7.47E+4n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 in transgenic zebrafish embryo assessed as inhibition of intersegmental vessels formation measured 33 hrs post fertilization by ...


Citation and Details
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Danio rerio)
BDBM50429504
PNG
(CHEMBL2332846)
Show SMILES COc1cccc(NC(=O)Nc2ccc(Oc3ncnc4n[nH]cc34)cc2)c1
Show InChI InChI=1S/C19H16N6O3/c1-27-15-4-2-3-13(9-15)24-19(26)23-12-5-7-14(8-6-12)28-18-16-10-22-25-17(16)20-11-21-18/h2-11H,1H3,(H2,23,24,26)(H,20,21,22,25)
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n/an/a 8.20E+4n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 in transgenic zebrafish embryo assessed as inhibition of intersegmental vessels formation measured 33 hrs post fertilization by ...


Citation and Details
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Danio rerio)
BDBM50429486
PNG
(CHEMBL2332865)
Show SMILES Fc1ccc(NC(=O)Nc2ccc(Oc3ncnc4n[nH]cc34)cc2)cc1
Show InChI InChI=1S/C18H13FN6O2/c19-11-1-3-12(4-2-11)23-18(26)24-13-5-7-14(8-6-13)27-17-15-9-22-25-16(15)20-10-21-17/h1-10H,(H2,23,24,26)(H,20,21,22,25)
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n/an/a 8.94E+4n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 in transgenic zebrafish embryo assessed as inhibition of intersegmental vessels formation measured 33 hrs post fertilization by ...


Citation and Details
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Danio rerio)
BDBM50429489
PNG
(CHEMBL2332862)
Show SMILES CC(NC(=O)Nc1ccc(Oc2ncnc3n[nH]cc23)cc1)c1ccccc1
Show InChI InChI=1S/C20H18N6O2/c1-13(14-5-3-2-4-6-14)24-20(27)25-15-7-9-16(10-8-15)28-19-17-11-23-26-18(17)21-12-22-19/h2-13H,1H3,(H2,24,25,27)(H,21,22,23,26)
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n/an/a>9.82E+4n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 in transgenic zebrafish embryo assessed as inhibition of intersegmental vessels formation measured 33 hrs post fertilization by ...


Citation and Details
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Danio rerio)
BDBM50429502
PNG
(CHEMBL2332848)
Show SMILES Cc1cccc(NC(=O)Nc2ccc(Oc3ncnc4n[nH]cc34)cc2)c1C
Show InChI InChI=1S/C20H18N6O2/c1-12-4-3-5-17(13(12)2)25-20(27)24-14-6-8-15(9-7-14)28-19-16-10-23-26-18(16)21-11-22-19/h3-11H,1-2H3,(H2,24,25,27)(H,21,22,23,26)
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n/an/a 9.88E+4n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 in transgenic zebrafish embryo assessed as inhibition of intersegmental vessels formation measured 33 hrs post fertilization by ...


Citation and Details
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Danio rerio)
BDBM50429495
PNG
(CHEMBL2332856)
Show SMILES FC(F)(F)c1ccc(cc1)C(=O)Nc1cccc(Oc2ncnc3n[nH]cc23)c1
Show InChI InChI=1S/C19H12F3N5O2/c20-19(21,22)12-6-4-11(5-7-12)17(28)26-13-2-1-3-14(8-13)29-18-15-9-25-27-16(15)23-10-24-18/h1-10H,(H,26,28)(H,23,24,25,27)
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n/an/a>1.00E+5n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 in transgenic zebrafish embryo assessed as inhibition of intersegmental vessels formation measured 33 hrs post fertilization by ...


Citation and Details
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Danio rerio)
BDBM50429496
PNG
(CHEMBL2332855)
Show SMILES Brc1ccc(CC(=O)Nc2cccc(Oc3ncnc4n[nH]cc34)c2)cc1
Show InChI InChI=1S/C19H14BrN5O2/c20-13-6-4-12(5-7-13)8-17(26)24-14-2-1-3-15(9-14)27-19-16-10-23-25-18(16)21-11-22-19/h1-7,9-11H,8H2,(H,24,26)(H,21,22,23,25)
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n/an/a>1.00E+5n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 in transgenic zebrafish embryo assessed as inhibition of intersegmental vessels formation measured 33 hrs post fertilization by ...


Citation and Details
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Danio rerio)
BDBM50429497
PNG
(CHEMBL2332854)
Show SMILES FC(F)(F)c1ccc(CC(=O)Nc2cccc(Oc3ncnc4n[nH]cc34)c2)cc1
Show InChI InChI=1S/C20H14F3N5O2/c21-20(22,23)13-6-4-12(5-7-13)8-17(29)27-14-2-1-3-15(9-14)30-19-16-10-26-28-18(16)24-11-25-19/h1-7,9-11H,8H2,(H,27,29)(H,24,25,26,28)
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n/an/a>1.00E+5n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 in transgenic zebrafish embryo assessed as inhibition of intersegmental vessels formation measured 33 hrs post fertilization by ...


Citation and Details
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Danio rerio)
BDBM50429498
PNG
(CHEMBL2332853)
Show SMILES Brc1ccc(NC(=O)Nc2cccc(Oc3ncnc4n[nH]cc34)c2)cc1
Show InChI InChI=1S/C18H13BrN6O2/c19-11-4-6-12(7-5-11)23-18(26)24-13-2-1-3-14(8-13)27-17-15-9-22-25-16(15)20-10-21-17/h1-10H,(H2,23,24,26)(H,20,21,22,25)
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n/an/a>1.00E+5n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 in transgenic zebrafish embryo assessed as inhibition of intersegmental vessels formation measured 33 hrs post fertilization by ...


Citation and Details
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Danio rerio)
BDBM50429499
PNG
(CHEMBL2332852)
Show SMILES FC(F)(F)c1ccc(NC(=O)Nc2cccc(Oc3ncnc4n[nH]cc34)c2)cc1
Show InChI InChI=1S/C19H13F3N6O2/c20-19(21,22)11-4-6-12(7-5-11)26-18(29)27-13-2-1-3-14(8-13)30-17-15-9-25-28-16(15)23-10-24-17/h1-10H,(H2,26,27,29)(H,23,24,25,28)
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n/an/a>1.00E+5n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 in transgenic zebrafish embryo assessed as inhibition of intersegmental vessels formation measured 33 hrs post fertilization by ...


Citation and Details
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Danio rerio)
BDBM50429487
PNG
(CHEMBL2332864)
Show SMILES O=C(NCC1CCCCC1)Nc1ccc(Oc2ncnc3n[nH]cc23)cc1
Show InChI InChI=1S/C19H22N6O2/c26-19(20-10-13-4-2-1-3-5-13)24-14-6-8-15(9-7-14)27-18-16-11-23-25-17(16)21-12-22-18/h6-9,11-13H,1-5,10H2,(H2,20,24,26)(H,21,22,23,25)
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n/an/a>1.00E+5n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 in transgenic zebrafish embryo assessed as inhibition of intersegmental vessels formation measured 33 hrs post fertilization by ...


Citation and Details
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Danio rerio)
BDBM50429501
PNG
(CHEMBL2332850)
Show SMILES COc1cccc(NC(=O)Nc2ccc(Oc3ncnc4n(C)ncc34)cc2)c1
Show InChI InChI=1S/C20H18N6O3/c1-26-18-17(11-23-26)19(22-12-21-18)29-15-8-6-13(7-9-15)24-20(27)25-14-4-3-5-16(10-14)28-2/h3-12H,1-2H3,(H2,24,25,27)
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n/an/a>1.00E+5n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 in transgenic zebrafish embryo assessed as inhibition of intersegmental vessels formation measured 33 hrs post fertilization by ...


Citation and Details
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Danio rerio)
BDBM50429485
PNG
(CHEMBL2332866)
Show SMILES O=C(Nc1ccc(Oc2ncnc3n[nH]cc23)cc1)Nc1ccc(cc1)N1CCOCC1
Show InChI InChI=1S/C22H21N7O3/c30-22(26-15-1-5-17(6-2-15)29-9-11-31-12-10-29)27-16-3-7-18(8-4-16)32-21-19-13-25-28-20(19)23-14-24-21/h1-8,13-14H,9-12H2,(H2,26,27,30)(H,23,24,25,28)
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n/an/a>1.00E+5n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 in transgenic zebrafish embryo assessed as inhibition of intersegmental vessels formation measured 33 hrs post fertilization by ...


Citation and Details
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Danio rerio)
BDBM50429508
PNG
(CHEMBL2332842)
Show SMILES Brc1ccc(NC(=O)Nc2ccc(Nc3ncnc4n[nH]cc34)cc2)cc1
Show InChI InChI=1S/C18H14BrN7O/c19-11-1-3-13(4-2-11)24-18(27)25-14-7-5-12(6-8-14)23-16-15-9-22-26-17(15)21-10-20-16/h1-10H,(H2,24,25,27)(H2,20,21,22,23,26)
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n/an/a>1.00E+5n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 in transgenic zebrafish embryo assessed as inhibition of intersegmental vessels formation measured 33 hrs post fertilization by ...


Citation and Details
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Danio rerio)
BDBM50429505
PNG
(CHEMBL2332845)
Show SMILES CC(NC(=O)Nc1ccc(Nc2ncnc3n[nH]cc23)cc1)c1ccccc1
Show InChI InChI=1S/C20H19N7O/c1-13(14-5-3-2-4-6-14)24-20(28)26-16-9-7-15(8-10-16)25-18-17-11-23-27-19(17)22-12-21-18/h2-13H,1H3,(H2,24,26,28)(H2,21,22,23,25,27)
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n/an/a>1.00E+5n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 in transgenic zebrafish embryo assessed as inhibition of intersegmental vessels formation measured 33 hrs post fertilization by ...


Citation and Details
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Danio rerio)
BDBM50429506
PNG
(CHEMBL2332844)
Show SMILES FC(F)(F)c1ccc(NC(=O)Nc2ccc(Nc3ncnc4n[nH]cc34)cc2)cc1
Show InChI InChI=1S/C19H14F3N7O/c20-19(21,22)11-1-3-13(4-2-11)27-18(30)28-14-7-5-12(6-8-14)26-16-15-9-25-29-17(15)24-10-23-16/h1-10H,(H2,27,28,30)(H2,23,24,25,26,29)
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n/an/a>1.00E+5n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 in transgenic zebrafish embryo assessed as inhibition of intersegmental vessels formation measured 33 hrs post fertilization by ...


Citation and Details
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Danio rerio)
BDBM50429488
PNG
(CHEMBL2332863)
Show SMILES O=C(NC1CCCCC1)Nc1ccc(Oc2ncnc3n[nH]cc23)cc1
Show InChI InChI=1S/C18H20N6O2/c25-18(22-12-4-2-1-3-5-12)23-13-6-8-14(9-7-13)26-17-15-10-21-24-16(15)19-11-20-17/h6-12H,1-5H2,(H2,22,23,25)(H,19,20,21,24)
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n/an/a>1.00E+5n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 in transgenic zebrafish embryo assessed as inhibition of intersegmental vessels formation measured 33 hrs post fertilization by ...


Citation and Details
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Danio rerio)
BDBM50429494
PNG
(CHEMBL2332857)
Show SMILES Brc1ccc(cc1)C(=O)Nc1cccc(Oc2ncnc3n[nH]cc23)c1
Show InChI InChI=1S/C18H12BrN5O2/c19-12-6-4-11(5-7-12)17(25)23-13-2-1-3-14(8-13)26-18-15-9-22-24-16(15)20-10-21-18/h1-10H,(H,23,25)(H,20,21,22,24)
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n/an/a>1.00E+5n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 in transgenic zebrafish embryo assessed as inhibition of intersegmental vessels formation measured 33 hrs post fertilization by ...


Citation and Details
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Danio rerio)
BDBM50429509
PNG
(CHEMBL2332841)
Show SMILES COc1cccc(NC(=O)Nc2ccc(Nc3ncnc4n[nH]cc34)cc2)c1
Show InChI InChI=1S/C19H17N7O2/c1-28-15-4-2-3-14(9-15)25-19(27)24-13-7-5-12(6-8-13)23-17-16-10-22-26-18(16)21-11-20-17/h2-11H,1H3,(H2,24,25,27)(H2,20,21,22,23,26)
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n/an/a>1.00E+5n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 in transgenic zebrafish embryo assessed as inhibition of intersegmental vessels formation measured 33 hrs post fertilization by ...


Citation and Details
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Danio rerio)
BDBM50429507
PNG
(CHEMBL2332843)
Show SMILES Cc1cccc(NC(=O)Nc2ccc(Nc3ncnc4n[nH]cc34)cc2)c1C
Show InChI InChI=1S/C20H19N7O/c1-12-4-3-5-17(13(12)2)26-20(28)25-15-8-6-14(7-9-15)24-18-16-10-23-27-19(16)22-11-21-18/h3-11H,1-2H3,(H2,25,26,28)(H2,21,22,23,24,27)
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n/an/a>1.00E+5n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 in transgenic zebrafish embryo assessed as inhibition of intersegmental vessels formation measured 33 hrs post fertilization by ...


Citation and Details
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Danio rerio)
BDBM50429490
PNG
(CHEMBL2332861)
Show SMILES O=C(Nc1ccc(Oc2ncnc3n[nH]cc23)cc1)Nc1cccnc1
Show InChI InChI=1S/C17H13N7O2/c25-17(23-12-2-1-7-18-8-12)22-11-3-5-13(6-4-11)26-16-14-9-21-24-15(14)19-10-20-16/h1-10H,(H2,22,23,25)(H,19,20,21,24)
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n/an/a>1.00E+5n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 in transgenic zebrafish embryo assessed as inhibition of intersegmental vessels formation measured 33 hrs post fertilization by ...


Citation and Details
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Danio rerio)
BDBM50429500
PNG
(CHEMBL2332851)
Show SMILES Cn1ncc2c(Oc3ccc(NC(=O)Nc4ccc(cc4)C(F)(F)F)cc3)ncnc12
Show InChI InChI=1S/C20H15F3N6O2/c1-29-17-16(10-26-29)18(25-11-24-17)31-15-8-6-14(7-9-15)28-19(30)27-13-4-2-12(3-5-13)20(21,22)23/h2-11H,1H3,(H2,27,28,30)
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n/an/a>1.00E+5n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 in transgenic zebrafish embryo assessed as inhibition of intersegmental vessels formation measured 33 hrs post fertilization by ...


Citation and Details
More data for this
Ligand-Target Pair