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Compile Data Set for Download or QSAR

Found 16 hits Enz. Inhib. hit(s) with Target = 'Xaa-Pro aminopeptidase 2' AND taxid = 10116   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Xaa-Pro aminopeptidase 2


(Rattus norvegicus)
BDBM50078402
PNG
((S)-1-((R)-3-Amino-2-hydroxy-5-methyl-hexanoyl)-py...)
Show SMILES CC(C)CC(N)[C@@H](O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(N)=O
Show InChI InChI=1S/C15H28N4O4/c1-8(2)7-10(16)12(20)15(23)19-6-4-5-11(19)14(22)18-9(3)13(17)21/h8-12,20H,4-7,16H2,1-3H3,(H2,17,21)(H,18,22)/t9-,10?,11-,12+/m0/s1
KEGG

UniProtKB/TrEMBL

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PC sid
UniChem

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Article
PubMed
n/an/a 310n/an/an/an/an/an/a



Pharmacia and Upjohn

Curated by ChEMBL


Assay Description
Activity against membrane bound rat aminopeptidase P


Citation and Details
More data for this
Ligand-Target Pair
Xaa-Pro aminopeptidase 2


(Rattus norvegicus)
BDBM50078397
PNG
(1-(3-Amino-2-hydroxy-5-methyl-hexanoyl)-pyrrolidin...)
Show SMILES CC(C)C[C@@H](N)C(O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(N)=O
Show InChI InChI=1S/C15H28N4O4/c1-8(2)7-10(16)12(20)15(23)19-6-4-5-11(19)14(22)18-9(3)13(17)21/h8-12,20H,4-7,16H2,1-3H3,(H2,17,21)(H,18,22)/t9-,10+,11-,12?/m0/s1
KEGG

UniProtKB/TrEMBL

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

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AffyNet 
Article
PubMed
n/an/a 560n/an/an/an/an/an/a



Pharmacia and Upjohn

Curated by ChEMBL


Assay Description
Activity against membrane bound rat aminopeptidase P


Citation and Details
More data for this
Ligand-Target Pair
Xaa-Pro aminopeptidase 2


(Rattus norvegicus)
BDBM50078393
PNG
((S)-1-[(S)-1-((2S,3R)-3-Amino-2-hydroxy-4-phenyl-b...)
Show SMILES C[C@H](NC(=O)[C@H](C)NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)[C@@H](O)[C@H](N)Cc1ccccc1)C(=O)N[C@@H](CS)C(N)=O
Show InChI InChI=1S/C29H43N7O7S/c1-16(25(39)32-17(2)26(40)34-20(15-44)24(31)38)33-27(41)21-10-6-12-35(21)28(42)22-11-7-13-36(22)29(43)23(37)19(30)14-18-8-4-3-5-9-18/h3-5,8-9,16-17,19-23,37,44H,6-7,10-15,30H2,1-2H3,(H2,31,38)(H,32,39)(H,33,41)(H,34,40)/t16-,17-,19+,20-,21-,22-,23-/m0/s1
KEGG

UniProtKB/TrEMBL

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PC sid
UniChem

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PubMed
n/an/a 660n/an/an/an/an/an/a



Pharmacia and Upjohn

Curated by ChEMBL


Assay Description
Activity against membrane bound rat aminopeptidase P


Citation and Details
More data for this
Ligand-Target Pair
Xaa-Pro aminopeptidase 2


(Rattus norvegicus)
BDBM50078396
PNG
((S)-1-(2-Mercapto-cyclopentanecarbonyl)-pyrrolidin...)
Show SMILES C[C@H](NC(=O)[C@@H]1CCCN1C(=O)C1CCCC1S)C(N)=O
Show InChI InChI=1S/C14H23N3O3S/c1-8(12(15)18)16-13(19)10-5-3-7-17(10)14(20)9-4-2-6-11(9)21/h8-11,21H,2-7H2,1H3,(H2,15,18)(H,16,19)/t8-,9?,10-,11?/m0/s1
KEGG

UniProtKB/TrEMBL

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
AffyNet 
Article
PubMed
n/an/a 3.40E+3n/an/an/an/an/an/a



Pharmacia and Upjohn

Curated by ChEMBL


Assay Description
Activity against membrane bound rat aminopeptidase P


Citation and Details
More data for this
Ligand-Target Pair
Xaa-Pro aminopeptidase 2


(Rattus norvegicus)
BDBM50078398
PNG
(2-[(S)-2-((S)-1-Carbamoyl-ethylcarbamoyl)-pyrrolid...)
Show SMILES C[C@H](NC(=O)[C@@H]1CCCN1C(CCc1ccccc1)C(O)=O)C(N)=O
Show InChI InChI=1S/C18H25N3O4/c1-12(16(19)22)20-17(23)14-8-5-11-21(14)15(18(24)25)10-9-13-6-3-2-4-7-13/h2-4,6-7,12,14-15H,5,8-11H2,1H3,(H2,19,22)(H,20,23)(H,24,25)/t12-,14-,15?/m0/s1
KEGG

UniProtKB/TrEMBL

GoogleScholar
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CHEMBL
PC cid
PC sid
UniChem

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AffyNet 
Article
PubMed
n/an/a 3.80E+3n/an/an/an/an/an/a



Pharmacia and Upjohn

Curated by ChEMBL


Assay Description
Activity against membrane bound rat aminopeptidase P


Citation and Details
More data for this
Ligand-Target Pair
Xaa-Pro aminopeptidase 2


(Rattus norvegicus)
BDBM50078401
PNG
((S)-1-[(S)-1-((2S,3R)-3-Amino-2-hydroxy-4-phenyl-b...)
Show SMILES C[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)[C@@H](O)[C@H](N)Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C23H33N5O5/c1-14(20(25)30)26-21(31)17-9-5-11-27(17)22(32)18-10-6-12-28(18)23(33)19(29)16(24)13-15-7-3-2-4-8-15/h2-4,7-8,14,16-19,29H,5-6,9-13,24H2,1H3,(H2,25,30)(H,26,31)/t14-,16+,17-,18-,19-/m0/s1
KEGG

UniProtKB/TrEMBL

GoogleScholar
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Purchase

CHEMBL
DrugBank
MMDB
PC cid
PC sid
UniChem

Patents


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Article
PubMed
n/an/a 4.10E+3n/an/an/an/an/an/a



Pharmacia and Upjohn

Curated by ChEMBL


Assay Description
Activity against membrane bound rat aminopeptidase P


Citation and Details
More data for this
Ligand-Target Pair
Xaa-Pro aminopeptidase 2


(Rattus norvegicus)
BDBM50078391
PNG
((S)-1-[(R)-3-((2S,3R)-3-Amino-2-hydroxy-4-phenyl-b...)
Show SMILES C[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CSCN1C(=O)[C@@H](O)[C@H](N)Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C22H31N5O5S/c1-13(19(24)29)25-20(30)16-8-5-9-26(16)21(31)17-11-33-12-27(17)22(32)18(28)15(23)10-14-6-3-2-4-7-14/h2-4,6-7,13,15-18,28H,5,8-12,23H2,1H3,(H2,24,29)(H,25,30)/t13-,15+,16-,17-,18-/m0/s1
KEGG

UniProtKB/TrEMBL

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

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AffyNet 
Article
PubMed
n/an/a 9.20E+3n/an/an/an/an/an/a



Pharmacia and Upjohn

Curated by ChEMBL


Assay Description
Activity against membrane bound rat aminopeptidase P


Citation and Details
More data for this
Ligand-Target Pair
Xaa-Pro aminopeptidase 2


(Rattus norvegicus)
BDBM50078392
PNG
((S)-1-((2R,3R)-3-Amino-2-hydroxy-5-methyl-hexanoyl...)
Show SMILES CC(C)C[C@@H](N)[C@@H](O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(N)=O
Show InChI InChI=1S/C15H28N4O4/c1-8(2)7-10(16)12(20)15(23)19-6-4-5-11(19)14(22)18-9(3)13(17)21/h8-12,20H,4-7,16H2,1-3H3,(H2,17,21)(H,18,22)/t9-,10+,11-,12+/m0/s1
KEGG

UniProtKB/TrEMBL

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

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AffyNet 
Article
PubMed
n/an/a 1.90E+4n/an/an/an/an/an/a



Pharmacia and Upjohn

Curated by ChEMBL


Assay Description
Activity against membrane bound rat aminopeptidase P


Citation and Details
More data for this
Ligand-Target Pair
Xaa-Pro aminopeptidase 2


(Rattus norvegicus)
BDBM50078395
PNG
((S)-1-(2-Hydroxycarbamoyl-cyclohexanecarbonyl)-pyr...)
Show SMILES C[C@H](NC(=O)[C@@H]1CCCN1C(=O)C1CCCCC1C(=O)NO)C(N)=O
Show InChI InChI=1S/C16H26N4O5/c1-9(13(17)21)18-15(23)12-7-4-8-20(12)16(24)11-6-3-2-5-10(11)14(22)19-25/h9-12,25H,2-8H2,1H3,(H2,17,21)(H,18,23)(H,19,22)/t9-,10?,11?,12-/m0/s1
KEGG

UniProtKB/TrEMBL

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 3.70E+4n/an/an/an/an/an/a



Pharmacia and Upjohn

Curated by ChEMBL


Assay Description
Activity against membrane bound rat aminopeptidase P


Citation and Details
More data for this
Ligand-Target Pair
Xaa-Pro aminopeptidase 2


(Rattus norvegicus)
BDBM50078390
PNG
((S)-1-((2S,3S)-3-Amino-2-hydroxy-5-methyl-hexanoyl...)
Show SMILES CC(C)C[C@H](N)[C@H](O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(N)=O
Show InChI InChI=1S/C15H28N4O4/c1-8(2)7-10(16)12(20)15(23)19-6-4-5-11(19)14(22)18-9(3)13(17)21/h8-12,20H,4-7,16H2,1-3H3,(H2,17,21)(H,18,22)/t9-,10-,11-,12-/m0/s1
KEGG

UniProtKB/TrEMBL

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 1.00E+5n/an/an/an/an/an/a



Pharmacia and Upjohn

Curated by ChEMBL


Assay Description
Activity against membrane bound rat aminopeptidase P


Citation and Details
More data for this
Ligand-Target Pair
Xaa-Pro aminopeptidase 2


(Rattus norvegicus)
BDBM50078396
PNG
((S)-1-(2-Mercapto-cyclopentanecarbonyl)-pyrrolidin...)
Show SMILES C[C@H](NC(=O)[C@@H]1CCCN1C(=O)C1CCCC1S)C(N)=O
Show InChI InChI=1S/C14H23N3O3S/c1-8(12(15)18)16-13(19)10-5-3-7-17(10)14(20)9-4-2-6-11(9)21/h8-11,21H,2-7H2,1H3,(H2,15,18)(H,16,19)/t8-,9?,10-,11?/m0/s1
KEGG

UniProtKB/TrEMBL

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
AffyNet 
Article
PubMed
n/an/a 1.50E+5n/an/an/an/an/an/a



Pharmacia and Upjohn

Curated by ChEMBL


Assay Description
Activity against membrane bound rat aminopeptidase P


Citation and Details
More data for this
Ligand-Target Pair
Xaa-Pro aminopeptidase 2


(Rattus norvegicus)
BDBM50078394
PNG
((S)-1-[(S)-1-((2S,3R)-3-Amino-2-hydroxy-4-phenyl-b...)
Show SMILES N[C@H](Cc1ccccc1)[C@H](O)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(N)=O
Show InChI InChI=1S/C20H28N4O4/c21-14(12-13-6-2-1-3-7-13)17(25)20(28)24-11-5-9-16(24)19(27)23-10-4-8-15(23)18(22)26/h1-3,6-7,14-17,25H,4-5,8-12,21H2,(H2,22,26)/t14-,15+,16+,17+/m1/s1
KEGG

UniProtKB/TrEMBL

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 3.90E+5n/an/an/an/an/an/a



Pharmacia and Upjohn

Curated by ChEMBL


Assay Description
Activity against membrane bound rat aminopeptidase P


Citation and Details
More data for this
Ligand-Target Pair
Xaa-Pro aminopeptidase 2


(Rattus norvegicus)
BDBM50078395
PNG
((S)-1-(2-Hydroxycarbamoyl-cyclohexanecarbonyl)-pyr...)
Show SMILES C[C@H](NC(=O)[C@@H]1CCCN1C(=O)C1CCCCC1C(=O)NO)C(N)=O
Show InChI InChI=1S/C16H26N4O5/c1-9(13(17)21)18-15(23)12-7-4-8-20(12)16(24)11-6-3-2-5-10(11)14(22)19-25/h9-12,25H,2-8H2,1H3,(H2,17,21)(H,18,23)(H,19,22)/t9-,10?,11?,12-/m0/s1
KEGG

UniProtKB/TrEMBL

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a>5.00E+5n/an/an/an/an/an/a



Pharmacia and Upjohn

Curated by ChEMBL


Assay Description
Activity against membrane bound rat aminopeptidase P


Citation and Details
More data for this
Ligand-Target Pair
Xaa-Pro aminopeptidase 2


(Rattus norvegicus)
BDBM50078399
PNG
((S)-1-((3R,4S)-4-Amino-3-hydroxy-6-methyl-heptanoy...)
Show SMILES CC(C)C[C@H](N)[C@H](O)CC(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(N)=O
Show InChI InChI=1S/C16H30N4O4/c1-9(2)7-11(17)13(21)8-14(22)20-6-4-5-12(20)16(24)19-10(3)15(18)23/h9-13,21H,4-8,17H2,1-3H3,(H2,18,23)(H,19,24)/t10-,11-,12-,13+/m0/s1
KEGG

UniProtKB/TrEMBL

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 1.20E+6n/an/an/an/an/an/a



Pharmacia and Upjohn

Curated by ChEMBL


Assay Description
Activity against membrane bound rat aminopeptidase P


Citation and Details
More data for this
Ligand-Target Pair
Xaa-Pro aminopeptidase 2


(Rattus norvegicus)
BDBM50078400
PNG
(1-[1-(3-Amino-2-hydroxy-4-phenyl-butyryl)-4-hydrox...)
Show SMILES C[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CC(O)CN1C(=O)[C@@H](O)[C@H](N)Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C23H33N5O6/c1-13(20(25)31)26-21(32)17-8-5-9-27(17)22(33)18-11-15(29)12-28(18)23(34)19(30)16(24)10-14-6-3-2-4-7-14/h2-4,6-7,13,15-19,29-30H,5,8-12,24H2,1H3,(H2,25,31)(H,26,32)/t13-,15?,16+,17-,18-,19-/m0/s1
KEGG

UniProtKB/TrEMBL

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 1.70E+6n/an/an/an/an/an/a



Pharmacia and Upjohn

Curated by ChEMBL


Assay Description
Activity against membrane bound rat aminopeptidase P


Citation and Details
More data for this
Ligand-Target Pair
Xaa-Pro aminopeptidase 2


(Rattus norvegicus)
BDBM50078395
PNG
((S)-1-(2-Hydroxycarbamoyl-cyclohexanecarbonyl)-pyr...)
Show SMILES C[C@H](NC(=O)[C@@H]1CCCN1C(=O)C1CCCCC1C(=O)NO)C(N)=O
Show InChI InChI=1S/C16H26N4O5/c1-9(13(17)21)18-15(23)12-7-4-8-20(12)16(24)11-6-3-2-5-10(11)14(22)19-25/h9-12,25H,2-8H2,1H3,(H2,17,21)(H,18,23)(H,19,22)/t9-,10?,11?,12-/m0/s1
KEGG

UniProtKB/TrEMBL

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a>5.00E+6n/an/an/an/an/an/a



Pharmacia and Upjohn

Curated by ChEMBL


Assay Description
Activity against membrane bound rat aminopeptidase P


Citation and Details
More data for this
Ligand-Target Pair